Youdong Wang

Youdong Wang

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Youdong Wang

Youdong Wang

Publications by authors named "Youdong Wang"

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Protocol development for discovery of angiogenesis inhibitors via automated methods using zebrafish.

PLoS One 2019 15;14(11):e0221796. Epub 2019 Nov 15.

Zebrafish Centre for Advanced Drug Discovery, Keenan Research Center, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221796PLOS
November 2019

Glutaminase Deficiency Caused by Short Tandem Repeat Expansion in .

N Engl J Med 2019 04;380(15):1433-1441

From Amsterdam University Medical Centers, University of Amsterdam, Departments of Clinical Chemistry, Pediatrics, and Clinical Genetics, Emma Children's Hospital, Amsterdam Gastroenterology and Metabolism (A.B.P.K., R.L., J.K., J. Meijer, L.A.T., M.T., M.W., R.J.A.W., H.R.W., C.D.M.K.), and United for Metabolic Diseases (A.B.P.K., R.J.A.W., H.R.W., C.D.M.K.), Amsterdam, and the Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht (J.J.F.A.V., J.H.V.), and the Project MinE ALS Sequencing Consortium (J.J.F.A.V., J.H.V.), Utrecht - all in the Netherlands; the Departments of Biochemistry and Molecular Biology and Medical Genetics, Cumming School of Medicine, and Alberta Children's Hospital Research Institute, University of Calgary, Calgary (M.T.-G.), Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute (P.A.R., M.J.J., M.S.K., J. MacIsaac, W.W.W., C.D.M.K.), the Faculty of Pharmaceutical Sciences (B.I.D., G.E.B.W., C.J.R.), and the Departments of Medical Genetics (C.M., I.-S.R.-B., W.W.W.) and Pediatrics (C.D.M.K.), University of British Columbia, Vancouver, the Zebrafish Centre for Advanced Drug Discovery, St. Michael's Hospital and University of Toronto (K.B.-A., F.K., M.L., Y.W., X.-Y.W.), the Centre for Applied Genomics, Genetics and Genome Biology, the Hospital for Sick Children (C.N., S.W.S., B.T., R.K.C.Y.), and the Department of Molecular Genetics (C.N., S.W.S., R.K.C.Y.), the McLaughlin Centre (S.W.S.), and the Departments of Medicine, Physiology, and Laboratory Medicine and Pathobiology, Institute of Medical Science (X.-Y.W.), University of Toronto, Toronto, and the Division of Medical Genetics, Department of Pediatrics, Children's Hospital Eastern Ontario, University of Ottawa, Ottawa (J.S.W., M.T.G.) - all in Canada; the Departments of Medicine and Physiology, National University of Singapore (M.A.P.), and the Translational Laboratory in Genetic Medicine, Agency for Science, Technology, and Research (M.A.P., B.S., X.X., J.Z.) - both in Singapore; Uppsala University, Department of Chemistry-Biomedical Center, Uppsala, Sweden (D.D.); Illumina, San Diego, CA (E.D., M.A.E.); Gene Structure and Disease Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD (B.H., D.K., K.U.); and the Department of Clinical Inherited Metabolic Disorders, Birmingham Children's Hospital, Birmingham, United Kingdom (S.S.).

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http://dx.doi.org/10.1056/NEJMoa1806627DOI Listing
April 2019

Development of a zebrafish sepsis model for high-throughput drug discovery.

Mol Med 2017 07 7;23:134-148. Epub 2017 Jun 7.

Zebrafish Centre for Advanced Drug Discovery, St. Michael's Hospital, 209 Victoria St, Toronto, Ontario, Canada M5B 1T8.

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http://dx.doi.org/10.2119/molmed.2016.00188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522968PMC
July 2017

A Model of Excitotoxic Brain Injury in Larval Zebrafish: Potential Application for High-Throughput Drug Evaluation to Treat Traumatic Brain Injury.

Zebrafish 2016 06 30;13(3):161-9. Epub 2016 Mar 30.

1 Institute of Medical Sciences, University of Toronto , Toronto, Ontario, Canada .

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http://dx.doi.org/10.1089/zeb.2015.1188DOI Listing
June 2016

Chromosome Condensation 1-Like (Chc1L) Is a Novel Tumor Suppressor Involved in Development of Histiocyte-Rich Neoplasms.

PLoS One 2015 20;10(8):e0135755. Epub 2015 Aug 20.

Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada; Department of Medicine & Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135755PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546397PMC
May 2016

Knockdown of ZNF403 inhibits cell proliferation and induces G2/M arrest by modulating cell-cycle mediators.

Mol Cell Biochem 2012 Jun 19;365(1-2):211-22. Epub 2012 Feb 19.

Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital and Cancer Research Institute, Central South University, Changsha 410008, Hunan Province, China.

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http://dx.doi.org/10.1007/s11010-012-1262-6DOI Listing
June 2012

Expression and characterization of recombinant Rhizopus oryzae lipase for enzymatic biodiesel production.

Bioresour Technol 2011 Oct 24;102(20):9810-3. Epub 2011 Jul 24.

College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.

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http://dx.doi.org/10.1016/j.biortech.2011.07.070DOI Listing
October 2011

Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer.

Eur Urol 2010 Sep 22;58(3):418-26. Epub 2010 May 22.

Keenan Research Center, Li Ka Shing Knowledge Institute, St. Michael's Hospital and Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.eururo.2010.05.024DOI Listing
September 2010

Characterisation and biological activities of proanthocyanidins from the barks of Pinus massonian and Acacia mearnsii.

Nat Prod Res 2010 Apr;24(6):590-8

College of Chemical Engineering, Nanjing Forestry University, Nanjing, China.

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http://dx.doi.org/10.1080/14786410903194472DOI Listing
April 2010

Enhanced adaptive immunity in mice lacking the immunoinhibitory adaptor Hacs1.

FASEB J 2010 Mar 18;24(3):947-56. Epub 2009 Nov 18.

St. Michael's Hospital, 30 Bond St., Queen Wing, Rm 8-019, Toronto, ON, Canada M5B 1W8.

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http://dx.doi.org/10.1096/fj.09-140806DOI Listing
March 2010

Effect of digital problem-based learning cases on student learning outcomes in ophthalmology courses.

Arch Ophthalmol 2009 Sep;127(9):1211-4

Department of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Heping District, Shenyang City 110005, China.

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http://dx.doi.org/10.1001/archophthalmol.2009.110DOI Listing
September 2009

Identification of a novel isoform of Murr1 transcript, U2mu, which is transcribed from the portions of two closely located but oppositely oriented genes.

Genes Genet Syst 2002 Oct;77(5):377-81

Department of Biomolecular Sciences, Saga Medical School, Japan.

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http://dx.doi.org/10.1266/ggs.77.377DOI Listing
October 2002