Dr. You-Lin Tain, MD, PhD - Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital - Professor

Dr. You-Lin Tain

MD, PhD

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital

Professor

Kaohsiung | Taiwan

Additional Specialties: Pediatric Nephrology

ORCID logohttps://orcid.org/0000-0002-7059-6407


Top Author

Dr. You-Lin Tain, MD, PhD - Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital - Professor

Dr. You-Lin Tain

MD, PhD

Introduction

Primary Affiliation: Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital - Kaohsiung , Taiwan

Additional Specialties:

Research Interests:


View Dr. You-Lin Tain’s Resume / CV

Education

Jan 2004 - Dec 2007
University of Florida
PhD
Physiology and Functional genomics
Sep 1999 - Dec 2002
Chang Gung University
Master of science
Graduate Institute of Clinical Medicine
Sep 1985 - Jun 1992
China Medical University
MD
Medicine

Experience

Jul 2017
Department of Medical Research and development, Kaohsiung Chang Gung Memorial Hospital
Director
Jan 2015
Kaohsiung Chang Gung Memorial Hospital
Professor
Pediatrics
Jan 2015
Chang Gung University, College of Medicine
Professor
Pediatrics

Publications

362Publications

4162Reads

30Profile Views

800PubMed Central Citations

Maternal high fructose-induced hippocampal neuroinflammation in the adult female offspring via PPARγ-NF-κB signaling.

J Nutr Biochem 2020 Jul 21;81:108378. Epub 2020 Mar 21.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 83301, Taiwan, ROC; Department of Senior Citizen Services, National Tainan Institute of Nursing, Tainan, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2020.108378DOI Listing
July 2020
3.794 Impact Factor

Anomalous AMPK-regulated angiotensin ATR expression and SIRT1-mediated mitochondrial biogenesis at RVLM in hypertension programming of offspring to maternal high fructose exposure.

J Biomed Sci 2020 May 23;27(1):68. Epub 2020 May 23.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 83301, Taiwan.

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http://dx.doi.org/10.1186/s12929-020-00660-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245869PMC
May 2020
2.736 Impact Factor

Early-Life Programming and Reprogramming of Adult Kidney Disease and Hypertension: The Interplay between Maternal Nutrition and Oxidative Stress.

Int J Mol Sci 2020 May 18;21(10). Epub 2020 May 18.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms21103572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278949PMC
May 2020
2.862 Impact Factor

Long term N-acetylcysteine administration rescues liver steatosis via endoplasmic reticulum stress with unfolded protein response in mice.

Lipids Health Dis 2020 May 25;19(1):105. Epub 2020 May 25.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung City, Taiwan.

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http://dx.doi.org/10.1186/s12944-020-01274-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249367PMC
May 2020
2.219 Impact Factor

Effects of Maternal Resveratrol on Maternal High-Fat Diet/Obesity with or without Postnatal High-Fat Diet.

Int J Mol Sci 2020 May 12;21(10). Epub 2020 May 12.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms21103428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279178PMC
May 2020
2.862 Impact Factor

Maternal Resveratrol Treatment Re-Programs and Maternal High-Fat Diet-Induced Retroperitoneal Adiposity in Male Offspring.

Int J Environ Res Public Health 2020 04 17;17(8). Epub 2020 Apr 17.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijerph17082780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215689PMC
April 2020
2.063 Impact Factor

Light and Circadian Signaling Pathway in Pregnancy: Programming of Adult Health and Disease.

Int J Mol Sci 2020 Mar 23;21(6). Epub 2020 Mar 23.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms21062232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139376PMC
March 2020
2.862 Impact Factor

Rats with prenatal dexamethasone exposure and postnatal high-fat diet exhibited insulin resistance, and spatial learning and memory impairment: effects of enriched environment.

Neuroreport 2020 02;31(3):265-273

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung.

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http://dx.doi.org/10.1097/WNR.0000000000001406DOI Listing
February 2020
1.644 Impact Factor

Whether AICAR in Pregnancy or Lactation Prevents Hypertension Programmed by High Saturated Fat Diet: A Pilot Study.

Nutrients 2020 Feb 11;12(2). Epub 2020 Feb 11.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/nu12020448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071394PMC
February 2020
3.148 Impact Factor

Rats with prenatal dexamethasone exposure and postnatal high-fat diet exhibited insulin resistance, and spatial learning and memory impairment: effects of enriched environment.

Neuroreport 2020 Feb 18. Epub 2020 Feb 18.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung.

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http://dx.doi.org/10.1097/WNR.0000000000001406DOI Listing
February 2020
1.644 Impact Factor

Resveratrol treatment improves the altered metabolism and related dysbiosis of gut programed by prenatal high-fat diet and postnatal high-fat diet exposure.

J Nutr Biochem 2020 01 27;75:108260. Epub 2019 Oct 27.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2019.108260DOI Listing
January 2020
3.794 Impact Factor

Association of Trimethylamine, Trimethylamine N-oxide, and Dimethylamine with Cardiovascular Risk in Children with Chronic Kidney Disease.

J Clin Med 2020 Jan 25;9(2). Epub 2020 Jan 25.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/jcm9020336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074377PMC
January 2020

Hypertension Programmed by Perinatal High-Fat Diet: Effect of Maternal Gut Microbiota-Targeted Therapy.

Nutrients 2019 Dec 2;11(12). Epub 2019 Dec 2.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/nu11122908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950030PMC
December 2019
3.148 Impact Factor

Young rats with increased circulatory asymmetric dimethylarginine exhibited spatial deficit and alterations in dorsal hippocampus brain-derived neurotrophic factor and asymmetric dimethylarginine: Effects of melatonin.

Int J Dev Neurosci 2019 Nov 21;78:83-89. Epub 2019 Sep 21.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, 833, Taiwan.

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http://dx.doi.org/10.1016/j.ijdevneu.2019.09.003DOI Listing
November 2019
2 Reads
2.580 Impact Factor

Ba-Wei-Die-Huang-Wan (Hachimi-jio-gan) can ameliorate ketamine-induced cystitis by modulating neuroreceptors, inflammatory mediators, and fibrogenesis in a rat model.

Neurourol Urodyn 2019 11 20;38(8):2159-2169. Epub 2019 Sep 20.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC.

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http://dx.doi.org/10.1002/nau.24165DOI Listing
November 2019
2 Reads
2.873 Impact Factor

The Association between Nitric Oxide Pathway, Blood Pressure Abnormalities, and Cardiovascular Risk Profile in Pediatric Chronic Kidney Disease.

Int J Mol Sci 2019 Oct 24;20(21). Epub 2019 Oct 24.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms20215301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862290PMC
October 2019
2.862 Impact Factor

Targeting on Gut Microbial Metabolite Trimethylamine-N-Oxide and Short-Chain Fatty Acid to Prevent Maternal High-Fructose-Diet-Induced Developmental Programming of Hypertension in Adult Male Offspring.

Mol Nutr Food Res 2019 09 24;63(18):e1900073. Epub 2019 Jul 24.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, 833, Taiwan.

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http://dx.doi.org/10.1002/mnfr.201900073DOI Listing
September 2019
5 Reads
4.603 Impact Factor

Maternal Exposure to Bisphenol A Combined with High-Fat Diet-Induced Programmed Hypertension in Adult Male Rat Offspring: Effects of Resveratrol.

Int J Mol Sci 2019 Sep 6;20(18). Epub 2019 Sep 6.

Departments of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms20184382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770559PMC
September 2019
2 Reads
2.862 Impact Factor

Protection of Male Rat Offspring against Hypertension Programmed by Prenatal Dexamethasone Administration and Postnatal High-Fat Diet with the Nrf2 Activator Dimethyl Fumarate during Pregnancy.

Int J Mol Sci 2019 Aug 14;20(16). Epub 2019 Aug 14.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms20163957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719242PMC
August 2019
1 Read
2.862 Impact Factor

Resveratrol prevents combined prenatal N-nitro-L-arginine-methyl ester (L-NAME) treatment plus postnatal high-fat diet induced programmed hypertension in adult rat offspring: interplay between nutrient-sensing signals, oxidative stress and gut microbiota.

J Nutr Biochem 2019 08 24;70:28-37. Epub 2019 Apr 24.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2019.04.002DOI Listing
August 2019
18 Reads
3.794 Impact Factor

Blood Pressure Abnormalities Associated with Gut Microbiota-Derived Short Chain Fatty Acids in Children with Congenital Anomalies of the Kidney and Urinary Tract.

J Clin Med 2019 Jul 24;8(8). Epub 2019 Jul 24.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/jcm8081090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722976PMC
July 2019
2 Reads

High fructose diet induces early mortality via autophagy factors accumulation in the rostral ventrolateral medulla as ameliorated by pioglitazone.

J Nutr Biochem 2019 07 8;69:87-97. Epub 2019 Apr 8.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 83301, Taiwan, ROC; National Tainan Institute of Nursing, Tainan 700, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2019.03.014DOI Listing
July 2019
3 Reads
3.794 Impact Factor

Impact of Arginine Nutrition and Metabolism during Pregnancy on Offspring Outcomes.

Nutrients 2019 Jun 27;11(7). Epub 2019 Jun 27.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/nu11071452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682918PMC
June 2019
1 Read
3.148 Impact Factor

The Impact of Maternal Fructose Exposure on Angiogenic Activity of Endothelial Progenitor Cells and Blood Flow Recovery After Critical Limb Ischemia in Rat Offspring.

Int J Mol Sci 2019 May 16;20(10). Epub 2019 May 16.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms20102429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566409PMC
May 2019
7 Reads
2.862 Impact Factor

Resveratrol Treatment Ameliorates Leptin Resistance and Adiposity Programed by the Combined Effect of Maternal and Post-Weaning High-Fat Diet.

Mol Nutr Food Res 2019 Apr 20:e1801385. Epub 2019 Apr 20.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, College of Medicine, Chang Gung University,, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1002/mnfr.201801385DOI Listing
April 2019
4 Reads
4.603 Impact Factor

The Good, the Bad, and the Ugly of Pregnancy Nutrients and Developmental Programming of Adult Disease.

Nutrients 2019 Apr 20;11(4). Epub 2019 Apr 20.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/nu11040894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520975PMC
April 2019
2 Reads
3.148 Impact Factor

Pioglitazone reversed the fructose-programmed astrocytic glycolysis and oxidative phosphorylation of female rat offspring.

Am J Physiol Endocrinol Metab 2019 04 22;316(4):E622-E634. Epub 2019 Jan 22.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, Republic of China.

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http://dx.doi.org/10.1152/ajpendo.00408.2018DOI Listing
April 2019
6 Reads
3.785 Impact Factor

Maternal high-fat diet sex-specifically alters placental morphology and transcriptome in rats: Assessment by next-generation sequencing.

Placenta 2019 03 12;78:44-53. Epub 2019 Mar 12.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.placenta.2019.03.004DOI Listing
March 2019
2 Reads
2.710 Impact Factor

Regulation of Nitric Oxide Production in the Developmental Programming of Hypertension and Kidney Disease.

Int J Mol Sci 2019 Feb 5;20(3). Epub 2019 Feb 5.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms20030681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386843PMC
February 2019
3 Reads
2.862 Impact Factor

Utility of human leukocyte antigen-B*58: 01 genotyping and patient outcomes.

Pharmacogenet Genomics 2019 01;29(1):1-8

School of Pharmacy.

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http://dx.doi.org/10.1097/FPC.0000000000000359DOI Listing
January 2019
4 Reads
3.481 Impact Factor

Additional file 2: of Prenatal dexamethasone and postnatal high-fat diet have a synergistic effect of elevating blood pressure through a distinct programming mechanism of systemic and adipose renin–angiotensin systems

Figshare

Figure S1. The mRNA expressions of indicated reference genes in rat adipose tissue. Two micrograms cDNA was used for each sample and PCR was performed for CYC, GAPDH, RPL17, B2M, and β-actin. Among the five reference genes, GAPDH had the smallest coefficient of variance (CV). N = 3/group. Abbreviations: CYC, cyclophilin A; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; RPL17, Ribosomal protein L17; B2M, β2 microglobulin. (TIFF 590 kb)

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2018
14 Reads

The Double-Edged Sword Effects of Maternal Nutrition in the Developmental Programming of Hypertension.

Nutrients 2018 Dec 4;10(12). Epub 2018 Dec 4.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/nu10121917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316180PMC
December 2018
3 Reads
3.148 Impact Factor

Regulation of Leptin Methylation Not via Apoptosis by Melatonin in the Rescue of Chronic Programming Liver Steatosis.

Int J Mol Sci 2018 Nov 12;19(11). Epub 2018 Nov 12.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, Kaohsiung 83301, Taiwan.

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http://www.mdpi.com/1422-0067/19/11/3565
Publisher Site
http://dx.doi.org/10.3390/ijms19113565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274685PMC
November 2018
7 Reads
2.862 Impact Factor

Mortality Risks among Various Primary Renal Diseases in Children and Adolescents on Chronic Dialysis.

J Clin Med 2018 Nov 5;7(11). Epub 2018 Nov 5.

Clinical Immunological Center, China Medical University Medical College and Hospital, Taichung 404, Taiwan.

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http://www.mdpi.com/2077-0383/7/11/414
Publisher Site
http://dx.doi.org/10.3390/jcm7110414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262556PMC
November 2018
53 Reads

Gut Microbiota-Dependent Trimethylamine -Oxide Pathway Associated with Cardiovascular Risk in Children with Early-Stage Chronic Kidney Disease.

Int J Mol Sci 2018 Nov 22;19(12). Epub 2018 Nov 22.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Kaohsiung, 833, Taiwan.

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http://dx.doi.org/10.3390/ijms19123699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320870PMC
November 2018
5 Reads
2.862 Impact Factor

Maternal Melatonin Therapy Attenuates Methyl-Donor Diet-Induced Programmed Hypertension in Male Adult Rat Offspring.

Nutrients 2018 Oct 2;10(10). Epub 2018 Oct 2.

Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.

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http://www.mdpi.com/2072-6643/10/10/1407
Publisher Site
http://dx.doi.org/10.3390/nu10101407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213858PMC
October 2018
4 Reads
3.150 Impact Factor

Maternal Administration of Probiotic or Prebiotic Prevents Male Adult Rat Offspring against Developmental Programming of Hypertension Induced by High Fructose Consumption in Pregnancy and Lactation.

Nutrients 2018 Sep 4;10(9). Epub 2018 Sep 4.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://www.mdpi.com/2072-6643/10/9/1229
Publisher Site
http://dx.doi.org/10.3390/nu10091229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163452PMC
September 2018
7 Reads
3.150 Impact Factor

Early Postweaning Treatment with Dimethyl Fumarate Prevents Prenatal Dexamethasone- and Postnatal High-Fat Diet-Induced Programmed Hypertension in Male Rat Offspring.

Oxid Med Cell Longev 2018 15;2018:5343462. Epub 2018 Feb 15.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1155/2018/5343462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832129PMC
September 2018
31 Reads
2 Citations

Developmental Programming of the Metabolic Syndrome: Can We Reprogram with Resveratrol?

Int J Mol Sci 2018 Aug 31;19(9). Epub 2018 Aug 31.

Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.

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http://www.mdpi.com/1422-0067/19/9/2584
Publisher Site
http://dx.doi.org/10.3390/ijms19092584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164855PMC
August 2018
26 Reads
1 Citation
2.862 Impact Factor

Melatonin alleviates liver steatosis induced by prenatal dexamethasone exposure and postnatal high-fat diet.

Exp Ther Med 2018 Aug 6;16(2):917-924. Epub 2018 Jun 6.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung 83301, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/etm.2018.6256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090450PMC
August 2018
45 Reads
0.941 Impact Factor

Maternal Resveratrol Therapy Protects Male Rat Offspring against Programmed Hypertension Induced by TCDD and Dexamethasone Exposures: Is It Relevant to Aryl Hydrocarbon Receptor?

Int J Mol Sci 2018 Aug 20;19(8). Epub 2018 Aug 20.

Departments of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms19082459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121911PMC
August 2018
14 Reads
2.862 Impact Factor

Resveratrol ameliorates maternal and post-weaning high-fat diet-induced nonalcoholic fatty liver disease via renin-angiotensin system.

Lipids Health Dis 2018 Jul 28;17(1):178. Epub 2018 Jul 28.

Department of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, 123 Ta-Pei Road, Niao Sung, Kaohsiung, 83301, Taiwan, Republic of China.

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http://dx.doi.org/10.1186/s12944-018-0824-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064630PMC
July 2018
7 Reads
2.220 Impact Factor

Biochemical basis for pharmacological intervention as a reprogramming strategy against hypertension and kidney disease of developmental origin.

Biochem Pharmacol 2018 07 6;153:82-90. Epub 2018 Jan 6.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2018.01.014DOI Listing
July 2018
14 Reads
6 Citations
5.010 Impact Factor

Postnatal high-fat diet sex-specifically exacerbates prenatal dexamethasone-induced hypertension: Mass spectrometry-based quantitative proteomic approach.

J Nutr Biochem 2018 07 22;57:268-275. Epub 2018 Apr 22.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2018.04.006DOI Listing
July 2018
23 Reads
3.794 Impact Factor

AMP-Activated Protein Kinase as a Reprogramming Strategy for Hypertension and Kidney Disease of Developmental Origin.

Int J Mol Sci 2018 Jun 12;19(6). Epub 2018 Jun 12.

Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms19061744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032132PMC
June 2018
10 Reads
3 Citations
2.862 Impact Factor

EQ-5D-Y for the assessment of health-related quality of life among Taiwanese youth with mild-to-moderate chronic kidney disease.

Int J Qual Health Care 2018 May;30(4):298-305

Department of Pediatrics, Division of Pediatric Nephrology, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, 123 Dabi Road, Niausung, Kaohsiung 83301, Taiwan.

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http://dx.doi.org/10.1093/intqhc/mzy011DOI Listing
May 2018
12 Reads
1.584 Impact Factor

Hydrogen Sulfide in Hypertension and Kidney Disease of Developmental Origins.

Int J Mol Sci 2018 May 11;19(5). Epub 2018 May 11.

Departments of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms19051438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983690PMC
May 2018
10 Reads
2.862 Impact Factor

Maternal Melatonin Therapy Attenuated Maternal High-Fructose Combined with Post-Weaning High-Salt Diets-Induced Hypertension in Adult Male Rat Offspring.

Molecules 2018 Apr 11;23(4). Epub 2018 Apr 11.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017187PMC
April 2018
30 Reads
2.420 Impact Factor

Translational insights on developmental origins of metabolic syndrome: Focus on fructose consumption.

Biomed J 2018 04;41(2):96-101

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.bj.2018.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138777PMC
April 2018
39 Reads
3 Citations

Combined maternal and postnatal high-fat diet leads to metabolic syndrome and is effectively reversed by resveratrol: a multiple-organ study.

Sci Rep 2018 04 4;8(1):5607. Epub 2018 Apr 4.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1038/s41598-018-24010-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884801PMC
April 2018
23 Reads
1 Citation
5.080 Impact Factor

Resveratrol Prevents the Development of Hypertension Programmed by Maternal Plus Post-Weaning High-Fructose Consumption through Modulation of Oxidative Stress, Nutrient-Sensing Signals, and Gut Microbiota.

Mol Nutr Food Res 2018 Apr 30:e1800066. Epub 2018 Apr 30.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, 833, Taiwan.

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http://dx.doi.org/10.1002/mnfr.201800066DOI Listing
April 2018
8 Reads
4 Citations
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Potential Orphan Drug Therapy of Intravesical Liposomal Onabotulinumtoxin-A for Ketamine-Induced Cystitis by Mucosal Protection and Anti-inflammation in a Rat Model.

Sci Rep 2018 04 11;8(1):5795. Epub 2018 Apr 11.

Division of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1038/s41598-018-24239-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895575PMC
April 2018
25 Reads
5.080 Impact Factor

Prenatal Metformin Therapy Attenuates Hypertension of Developmental Origin in Male Adult Offspring Exposed to Maternal High-Fructose and Post-Weaning High-Fat Diets.

Int J Mol Sci 2018 Apr 3;19(4). Epub 2018 Apr 3.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms19041066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979307PMC
April 2018
12 Reads
1 Citation
2.862 Impact Factor

Prenatal dexamethasone and postnatal high-fat diet have a synergistic effect of elevating blood pressure through a distinct programming mechanism of systemic and adipose renin-angiotensin systems.

Lipids Health Dis 2018 Mar 14;17(1):50. Epub 2018 Mar 14.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, #123, Ta-Pei Road, Niao-Sung District, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1186/s12944-018-0701-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853160PMC
March 2018
33 Reads
2.220 Impact Factor

Epidemiology and outcomes of community-acquired and hospital-acquired acute kidney injury in children and adolescents.

Pediatr Res 2018 03 3;83(3):622-629. Epub 2018 Jan 3.

Division of Pediatric Nephrology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1038/pr.2017.262DOI Listing
March 2018
21 Reads
1 Citation
2.314 Impact Factor

Prenatal Dexamethasone Exposure Programs the Development of the Pancreas and the Secretion of Insulin in Rats.

Pediatr Neonatol 2017 04 18;58(2):135-144. Epub 2016 Jun 18.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University, College of Medicine, Kaohsiung, Taiwan; Department of Traditional Chinese Medicine, Chang Gung University, Linkow, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.pedneo.2016.02.008DOI Listing
April 2017
39 Reads
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Effects of high fructose intake on the development of hypertension in the spontaneously hypertensive rats: the role of ATR/gp91 signaling in the rostral ventrolateral medulla.

J Nutr Biochem 2017 03 5;41:73-83. Epub 2016 Dec 5.

Department of Pharmacy, Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung County 90741, Taiwan, Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2016.11.013DOI Listing
March 2017
35 Reads
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3.794 Impact Factor

PPARs Link Early Life Nutritional Insults to Later Programmed Hypertension and Metabolic Syndrome.

Tain YL, Hsu CN, Chan JY, International journal of molecular sciences, 2016, vol. 17, no. 1, 2016

http://europepmc.org/abstract/med/26712739

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2016
13 Reads

Targeting arachidonic acid pathway to prevent programmed hypertension in maternal fructose-fed male adult rat offspring.

J Nutr Biochem 2016 12 7;38:86-92. Epub 2016 Sep 7.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan. Electronic address:

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December 2016
26 Reads
8 Citations
3.794 Impact Factor

Targeting on Asymmetric Dimethylarginine-Related Nitric Oxide-Reactive Oxygen Species Imbalance to Reprogram the Development of Hypertension.

Int J Mol Sci 2016 Dec 2;17(12). Epub 2016 Dec 2.

Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms17122020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187820PMC
December 2016
46 Reads
10 Citations
2.862 Impact Factor

Maternal melatonin or N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and renal transcriptome to prevent prenatal N-Nitro-L-arginine-methyl ester (L-NAME)-induced fetal programming of hypertension in adult male offspring.

Am J Obstet Gynecol 2016 Nov 22;215(5):636.e1-636.e72. Epub 2016 Jul 22.

Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan; School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2016.07.036DOI Listing
November 2016
72 Reads
7 Citations
4.704 Impact Factor

Maternal Fructose Intake Affects Transcriptome Changes and Programmed Hypertension in Offspring in Later Life.

Nutrients 2016 Nov 25;8(12). Epub 2016 Nov 25.

Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/nu8120757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5188412PMC
November 2016
46 Reads
8 Citations
3.150 Impact Factor

Sex differences in renal transcriptome and programmed hypertension in offspring exposed to prenatal dexamethasone.

Steroids 2016 11 10;115:40-46. Epub 2016 Aug 10.

Department of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1016/j.steroids.2016.08.006DOI Listing
November 2016
56 Reads
2 Citations
2.640 Impact Factor

Developmental programming of the metabolic syndrome: Next-generation sequencing analysis of transcriptome expression in a rat model of maternal high fructose intake.

Sheng Li Xue Bao 2016 Oct;68(5):557-567

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, Kaohsiung 83301.

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October 2016
22 Reads
3 Citations

Maternal Fructose Exposure Programs Metabolic Syndrome-Associated Bladder Overactivity in Young Adult Offspring.

Sci Rep 2016 10 5;6:34669. Epub 2016 Oct 5.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1038/srep34669DOI Listing
October 2016
42 Reads
2 Citations
5.080 Impact Factor

Etiology and pediatric chronic kidney disease progression: Taiwan Pediatric Renal Collaborative Study.

J Formos Med Assoc 2016 Sep 29;115(9):752-63. Epub 2015 Aug 29.

Department of Pediatrics, Ditmanson Medical Foundation Chiayi Christian Hospital, Chia-Yi City, Taiwan.

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http://dx.doi.org/10.1016/j.jfma.2015.07.019DOI Listing
September 2016
43 Reads
1.700 Impact Factor

Prenatal Dexamethasone and Postnatal High-Fat Diet Decrease Interferon Gamma Production through an Age-Dependent Histone Modification in Male Sprague-Dawley Rats.

Int J Mol Sci 2016 Sep 22;17(10). Epub 2016 Sep 22.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms17101610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085643PMC
September 2016
31 Reads
4 Citations
2.862 Impact Factor

Postnatal high-fat diet leads to spatial deficit, obesity, and central and peripheral inflammation in prenatal dexamethasone adult offspring rats.

Neuroreport 2016 08;27(11):818-25

aDepartment of Medical Administration, Pu-Li Christian Hospital bDepartment of Applied Chemistry, National Chi-Nan University, Nantou cDepartment of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung dDepartment of Traditional Medicine, Chang Gung University, Linkow, Taiwan.

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http://dx.doi.org/10.1097/WNR.0000000000000620DOI Listing
August 2016
26 Reads
1 Citation
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Melatonin Alleviates Liver Apoptosis in Bile Duct Ligation Young Rats.

Int J Mol Sci 2016 Aug 20;17(8). Epub 2016 Aug 20.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123 Ta-Pei Road, Niao Sung, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms17081365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000760PMC
August 2016
28 Reads
2 Citations
2.862 Impact Factor

Clinical characteristics and prevalence of complications of chronic kidney disease in children: the Taiwan Pediatric Renal Collaborative study.

Pediatr Nephrol 2016 07 5;31(7):1113-20. Epub 2016 Feb 5.

Division of Pediatric Nephrology, Department of Pediatrics, National Cheng Kung University Hospital, Tainan, Taiwan.

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http://dx.doi.org/10.1007/s00467-016-3325-5DOI Listing
July 2016
49 Reads
1 Citation
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N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers.

Biol Reprod 2016 07 1;95(1). Epub 2016 Jun 1.

Department of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1095/biolreprod.116.139766DOI Listing
July 2016
35 Reads
5 Citations
3.320 Impact Factor

Combined Intraperitoneal and Intrathecal Etanercept Reduce Increased Brain Tumor Necrosis Factor-Alpha and Asymmetric Dimethylarginine Levels and Rescues Spatial Deficits in Young Rats after Bile Duct Ligation.

Front Cell Neurosci 2016 23;10:167. Epub 2016 Jun 23.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung, Taiwan.

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http://dx.doi.org/10.3389/fncel.2016.00167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917524PMC
July 2016
29 Reads
5 Citations
4.290 Impact Factor

Early postnatal treatment with soluble epoxide hydrolase inhibitor or 15-deoxy-Δ(12,14)-prostagandin J2 prevents prenatal dexamethasone and postnatal high saturated fat diet induced programmed hypertension in adult rat offspring.

Prostaglandins Other Lipid Mediat 2016 07 19;124:1-8. Epub 2016 May 19.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.prostaglandins.2016.05.005DOI Listing
July 2016
35 Reads
5 Citations
2.380 Impact Factor

Homocysteine and Arginine-to-Asymmetric Dimethylarginine Ratio Associated With Blood Pressure Abnormalities in Children With Early Chronic Kidney Disease.

Circ J 2015 16;79(9):2031-7. Epub 2015 Jun 16.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine.

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http://dx.doi.org/10.1253/circj.CJ-15-0412DOI Listing
May 2016
19 Reads
2 Citations
3.940 Impact Factor

Incidence, Outcomes, and Risk Factors of Community-Acquired and Hospital-Acquired Acute Kidney Injury: A Retrospective Cohort Study.

Medicine (Baltimore) 2016 May;95(19):e3674

From the Department of Pharmacy (C-NH, C-HS, Y-CLW, H-LC), Division of Pediatric Surgery (J-HC) Nephrology, Department of Internal Medicine (C-TL), Department of Pediatric Surgery (J-HC), Division of Pediatric Nephrology, Department of Pediatrics (Y-LT), Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, and School of Pharmacy (C-NH), Kaohsiung Medical University, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1097/MD.0000000000003674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902543PMC
May 2016
59 Reads
4 Citations
5.723 Impact Factor

Ba-Wei-Die-Huang-Wan (Hachimi-jio-gan) can ameliorate cyclophosphamide-induced ongoing bladder overactivity and acidic adenosine triphosphate solution-induced hyperactivity on rats prestimulated bladder.

J Ethnopharmacol 2016 May 21;184:1-9. Epub 2015 Dec 21.

Division of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2015.12.026DOI Listing
May 2016
80 Reads
1 Citation
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Postnatal dexamethasone-induced programmed hypertension is related to the regulation of melatonin and its receptors.

Steroids 2016 Apr 24;108:1-6. Epub 2016 Feb 24.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.steroids.2016.02.017DOI Listing
April 2016
25 Reads
1 Citation
2.640 Impact Factor

Environmental stimulation rescues maternal high fructose intake-impaired learning and memory in female offspring: Its correlation with redistribution of histone deacetylase 4.

Neurobiol Learn Mem 2016 Apr 9;130:105-17. Epub 2016 Feb 9.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.nlm.2016.02.004DOI Listing
April 2016
62 Reads
2 Citations
3.652 Impact Factor

Programming Effects of Prenatal Glucocorticoid Exposure with a Postnatal High-Fat Diet in Diabetes Mellitus.

Int J Mol Sci 2016 Apr 8;17(4):533. Epub 2016 Apr 8.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University, College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms17040533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848989PMC
April 2016
32 Reads
5 Citations
2.862 Impact Factor

Early and late effects of prenatal corticosteroid treatment on the microRNA profiles of lung tissue in rats.

Yu HR, Li SC, Tseng WN, Tain YL, Chen CC, Sheen JM, Tiao MM, Kuo HC, Huang CC, Hsieh KS, Huang LT, Experimental and therapeutic medicine, 2016, vol. 11, no. 3, pp. 753-762, 2016

http://europepmc.org/abstract/med/26997989

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March 2016
13 Reads

Postnatal High-Fat Diet Increases Liver Steatosis and Apoptosis Threatened by Prenatal Dexamethasone through the Oxidative Effect.

Int J Mol Sci 2016 Mar 11;17(3):369. Epub 2016 Mar 11.

Department of Pediatrics, College of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, No. 123, Ta-Pei road, Niaohsung, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms17030369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813229PMC
March 2016
35 Reads
4 Citations
2.862 Impact Factor

Early and late effects of prenatal corticosteroid treatment on the microRNA profiles of lung tissue in rats.

Exp Ther Med 2016 Mar 13;11(3):753-762. Epub 2016 Jan 13.

Department of Pediatrics, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/etm.2016.2992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774352PMC
March 2016
30 Reads
1 Citation
0.941 Impact Factor

Compliance with risk management plan recommendations on laboratory monitoring of antitumor necrosis factor-α therapy in clinical practice.

J Formos Med Assoc 2016 Feb 23;115(2):83-93. Epub 2015 Oct 23.

School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jfma.2015.09.003DOI Listing
February 2016
24 Reads
1.700 Impact Factor

Maternal N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and prevents programmed hypertension in male offspring exposed to prenatal dexamethasone and postnatal high-fat diet.

Nitric Oxide 2016 Feb 29;53:6-12. Epub 2015 Dec 29.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan; Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.niox.2015.12.006DOI Listing
February 2016
40 Reads
9 Citations
3.521 Impact Factor

Low urinary citrulline/arginine ratio associated with blood pressure abnormalities and arterial stiffness in childhood chronic kidney disease.

J Am Soc Hypertens 2016 Feb 22;10(2):115-23. Epub 2015 Nov 22.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Kaohsiung, Taiwan; Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jash.2015.11.008DOI Listing
February 2016
45 Reads
2 Citations

Incidence and Risks of Congenital Anomalies of Kidney and Urinary Tract in Newborns: A Population-Based Case-Control Study in Taiwan.

Medicine (Baltimore) 2016 Feb;95(5):e2659

From the Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan (Y-LT); Department of Mathematical Sciences, Research Center for Mind, Brain, and Learning, National Chengchi University, Taipei, Taiwan (HL); Children's Hospital of China Medical University, Taichung, Taiwan (C-YL); Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan (C-NH); and School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan (C-NH).

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http://dx.doi.org/10.1097/MD.0000000000002659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748909PMC
February 2016
32 Reads
5 Citations
5.723 Impact Factor

Effects of melatonin on prenatal dexamethasone-induced epigenetic alterations in hippocampal morphology and reelin and glutamic acid decarboxylase 67 levels.

Dev Neurosci 2015 25;37(2):105-14. Epub 2015 Feb 25.

Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC.

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http://dx.doi.org/10.1159/000368768DOI Listing
January 2016
36 Reads
4 Citations
2.700 Impact Factor

Maternal Melatonin Therapy Rescues Prenatal Dexamethasone and Postnatal High-Fat Diet Induced Programmed Hypertension in Male Rat Offspring.

Front Physiol 2015 11;6:377. Epub 2015 Dec 11.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine Kaohsiung, Taiwan ; Department of Traditional Chinese Medicine, Chang Gung University Linkou, Taiwan.

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http://dx.doi.org/10.3389/fphys.2015.00377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675845PMC
December 2015
85 Reads
10 Citations

Cross-fostering increases TH1/TH2 expression in a prenatal dexamethasone exposure rat model.

PLoS One 2014 19;9(12):e115554. Epub 2014 Dec 19.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; Department of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115554PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272273PMC
December 2015
42 Reads
1 Citation
3.234 Impact Factor

PPARs Link Early Life Nutritional Insults to Later Programmed Hypertension and Metabolic Syndrome.

Int J Mol Sci 2015 Dec 24;17(1). Epub 2015 Dec 24.

Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms17010020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730267PMC
December 2015
24 Reads
15 Citations
2.862 Impact Factor

Reprogramming: A Preventive Strategy in Hypertension Focusing on the Kidney.

Int J Mol Sci 2015 Dec 25;17(1). Epub 2015 Dec 25.

Department of Nephrology and Hypertension, Laboratory of Renal and Vascular Biology, University Medical Center Utrecht, POB 85500, 3508 GA Utrecht, The Netherlands.

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http://dx.doi.org/10.3390/ijms17010023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730270PMC
December 2015
18 Reads
16 Citations
2.862 Impact Factor

Targeting redox balance to deprogramme obesity: are we starting early enough?

Authors:
You-Lin Tain

J Physiol 2015 Nov;593(21):4689-90

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1113/JP271450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626547PMC
November 2015
16 Reads
3 Citations
5.040 Impact Factor

Aliskiren in early postnatal life prevents hypertension and reduces asymmetric dimethylarginine in offspring exposed to maternal caloric restriction.

J Renin Angiotensin Aldosterone Syst 2015 Sep 15;16(3):506-13. Epub 2014 May 15.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taiwan Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, Taiwan

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http://dx.doi.org/10.1177/1470320313514123DOI Listing
September 2015
52 Reads
15 Citations
2.271 Impact Factor

Renal Transcriptome Analysis of Programmed Hypertension Induced by Maternal Nutritional Insults.

Int J Mol Sci 2015 Aug 3;16(8):17826-37. Epub 2015 Aug 3.

Departments of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.3390/ijms160817826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581224PMC
August 2015
54 Reads
13 Citations
2.862 Impact Factor

Prenatal dexamethasone-induced programmed hypertension and renal programming.

Life Sci 2015 Jul 25;132:41-8. Epub 2015 Apr 25.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung, Taiwan; Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2015.04.005DOI Listing
July 2015
46 Reads
10 Citations
2.702 Impact Factor

Maternal fructose-intake-induced renal programming in adult male offspring.

J Nutr Biochem 2015 Jun 26;26(6):642-50. Epub 2015 Feb 26.

Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan. Electronic address:

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June 2015
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Transcriptome analysis in rat kidneys: importance of genes involved in programmed hypertension.

Int J Mol Sci 2015 Mar 2;16(3):4744-58. Epub 2015 Mar 2.

Division of Nephrology, Departments of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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March 2015
33 Reads
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2.862 Impact Factor

Maternal citrulline supplementation prevents prenatal N(G)-nitro-L-arginine-methyl ester (L-NAME)-induced programmed hypertension in rats.

Biol Reprod 2015 Jan 13;92(1). Epub 2014 Nov 13.

Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Kaohsiung, Taiwan School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.

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January 2015
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Cross-fostering increases TH1/TH2 expression in a prenatal dexamethasone exposure rat model.

Kuo HC, Guo MM, Liu SF, Chen CC, Sheen JM, Yu HR, Tiao MM, Tain YL, Huang LT, PloS one, 2014, vol. 9, no. 12, pp. e115554, 2014

http://europepmc.org/abstract/med/25526616

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2014
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Metformin reduces asymmetric dimethylarginine and prevents hypertension in spontaneously hypertensive rats.

Transl Res 2014 Dec 7;164(6):452-9. Epub 2014 Aug 7.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; Chang Gung University, College of Medicine, Taoyuan, Taiwan; Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. Electronic address:

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December 2014
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Long-term effects of maternal citrulline supplementation on renal transcriptome prevention of nitric oxide depletion-related programmed hypertension: the impact of gene-nutrient interactions.

Int J Mol Sci 2014 Dec 15;15(12):23255-68. Epub 2014 Dec 15.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284764PMC
December 2014
27 Reads
7 Citations
2.862 Impact Factor

Melatonin therapy prevents programmed hypertension and nitric oxide deficiency in offspring exposed to maternal caloric restriction.

Oxid Med Cell Longev 2014 22;2014:283180. Epub 2014 Apr 22.

Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Kaohsiung 833, Taiwan.

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December 2014
16 Reads
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Prenatal dexamethasone exposure in rats results in long-term epigenetic histone modifications and tumour necrosis factor-α production decrease.

Immunology 2014 Dec;143(4):651-60

Department of Paediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Centre, Graduate Insititute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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December 2014
34 Reads
9 Citations
3.800 Impact Factor

Vascular endothelial growth factor-a in lactobacillus casei cell wall extract-induced coronary arteritis of a murine model.

Circ J 2014 14;78(3):752-62. Epub 2013 Dec 14.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine.

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December 2014
31 Reads
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Effects of AST-120 on blood concentrations of protein-bound uremic toxins and biomarkers of cardiovascular risk in chronic dialysis patients.

Blood Purif 2014 22;37(1):76-83. Epub 2014 Feb 22.

Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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November 2014
36 Reads
10 Citations
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Transcriptional regulation of programmed hypertension by melatonin: an epigenetic perspective.

Int J Mol Sci 2014 Oct 14;15(10):18484-95. Epub 2014 Oct 14.

Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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October 2014
18 Reads
10 Citations
2.862 Impact Factor

L-Arginine modulates neonatal lymphocyte proliferation through an interleukin-2 independent pathway.

Immunology 2014 Oct;143(2):184-92

Department of Paediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Centre, Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiug, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172135PMC
October 2014
52 Reads
4 Citations
3.800 Impact Factor

Melatonin prevents neonatal dexamethasone induced programmed hypertension: histone deacetylase inhibition.

J Steroid Biochem Mol Biol 2014 Oct 30;144 Pt B:253-9. Epub 2014 Jul 30.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan; Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.

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October 2014
24 Reads
11 Citations
3.630 Impact Factor

Melatonin prevents maternal fructose intake-induced programmed hypertension in the offspring: roles of nitric oxide and arachidonic acid metabolites.

J Pineal Res 2014 Aug 16;57(1):80-9. Epub 2014 Jun 16.

Department of Pediatrics, College of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, Kaohsiung, Taiwan; Center for Translational Research in Biomedical Sciences, College of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, Kaohsiung, Taiwan.

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August 2014
47 Reads
24 Citations
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Sonographic finding of persistent renal pelvic wall thickening in children.

Pediatr Neonatol 2014 Aug 25;55(4):269-74. Epub 2013 Dec 25.

Division of Pediatric Nephrology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan. Electronic address:

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August 2014
15 Reads
2 Citations
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Asymmetric and symmetric dimethylarginine are associated with coronary artery lesions in Kawasaki disease.

J Pediatr 2014 Aug 27;165(2):295-9. Epub 2014 May 27.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2014.04.031DOI Listing
August 2014
34 Reads
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N-acetylcysteine prevents hypertension via regulation of the ADMA-DDAH pathway in young spontaneously hypertensive rats.

Biomed Res Int 2013 17;2013:696317. Epub 2013 Dec 17.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123 Dabi Road, Niausung, Kaohsiung 833, Taiwan ; Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.

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July 2014
40 Reads
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Restoration of asymmetric dimethylarginine-nitric oxide balance to prevent the development of hypertension.

Int J Mol Sci 2014 Jul 2;15(7):11773-82. Epub 2014 Jul 2.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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July 2014
18 Reads
10 Citations
2.862 Impact Factor

Renoprotective effects of melatonin in young spontaneously hypertensive rats with L-NAME.

Pediatr Neonatol 2014 Jun 20;55(3):189-95. Epub 2013 Nov 20.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan; Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. Electronic address:

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June 2014
18 Reads
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Maternal citrulline supplementation prevents prenatal dexamethasone-induced programmed hypertension.

Free Radic Res 2014 May 17;48(5):580-6. Epub 2014 Mar 17.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine , Kaohsiung , Taiwan.

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May 2014
10 Reads
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Common carotid artery intima-media thickness is useful for diagnosis of the acute stage of Kawasaki disease.

BMC Pediatr 2014 Apr 10;14:98. Epub 2014 Apr 10.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, 123 Ta-Pei Road, Niaosung, Kaohsiung, Taiwan.

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April 2014
45 Reads
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Melatonin attenuates prenatal dexamethasone-induced blood pressure increase in a rat model.

J Am Soc Hypertens 2014 Apr 6;8(4):216-26. Epub 2014 Feb 6.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan; Department of Traditional Chinese Medicine, Chang Gung University, Linkow, Taiwan. Electronic address:

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April 2014
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Increased circulatory asymmetric dimethylarginine and multiple organ failure: bile duct ligation in rat as a model.

Int J Mol Sci 2014 Mar 5;15(3):3989-4006. Epub 2014 Mar 5.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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March 2014
19 Reads
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2.862 Impact Factor

Two different approaches to restore renal nitric oxide and prevent hypertension in young spontaneously hypertensive rats: l-citrulline and nitrate.

Transl Res 2014 Jan 8;163(1):43-52. Epub 2013 Oct 8.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan; Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan. Electronic address:

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January 2014
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RNA silencing targeting PIN (protein inhibitor of neuronal nitric oxide synthase) attenuates the development of hypertension in young spontaneously hypertensive rats.

J Am Soc Hypertens 2014 Jan 12;8(1):5-13. Epub 2013 Sep 12.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan; Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan. Electronic address:

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January 2014
32 Reads
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Asymmetric dimethylarginine is associated with developmental programming of adult kidney disease and hypertension in offspring of streptozotocin-treated mothers.

PLoS One 2013 7;8(2):e55420. Epub 2013 Feb 7.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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September 2013
10 Reads
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Renin angiotensin system blockade ameliorates lead nephropathy.

Biochem Biophys Res Commun 2013 Aug 26;438(2):359-63. Epub 2013 Jul 26.

Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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August 2013
93 Reads
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High citrulline-to-arginine ratio associated with blood pressure abnormalities in children with early chronic kidney disease.

Circ J 2013 20;77(1):181-7. Epub 2012 Sep 20.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.

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June 2013
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Urinary arginine methylation index associated with ambulatory blood pressure abnormalities in children with chronic kidney disease.

J Am Soc Hypertens 2012 Nov-Dec;6(6):385-92. Epub 2012 Oct 26.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Taiwan.

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May 2013
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Sex differences of oxidative stress to cholestatic liver and kidney injury in young rats.

Pediatr Neonatol 2013 Apr 8;54(2):95-101. Epub 2013 Jan 8.

Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.

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April 2013
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Melatonin regulates L-arginine transport and NADPH oxidase in young rats with bile duct ligation: role of protein kinase C.

Pediatr Res 2013 Apr 7;73(4 Pt 1):395-401. Epub 2013 Jan 7.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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April 2013
35 Reads
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Roles of melatonin in fetal programming in compromised pregnancies.

Int J Mol Sci 2013 Mar 6;14(3):5380-401. Epub 2013 Mar 6.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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March 2013
33 Reads
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Sensory dysfunction of bladder mucosa and bladder oversensitivity in a rat model of metabolic syndrome.

PLoS One 2012 19;7(9):e45578. Epub 2012 Sep 19.

Division of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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March 2013
23 Reads
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Fish omega-3 fatty acids induce liver fibrosis in the treatment of bile duct-ligated rats.

Dig Dis Sci 2013 Feb 1;58(2):440-7. Epub 2012 Dec 1.

Pediatrics Department, Kaohsiung Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, 123 Ta-Pei Road, Niao Song, Kaohsiung, 833, Taiwan.

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February 2013
31 Reads
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Roles of nitric oxide and asymmetric dimethylarginine in pregnancy and fetal programming.

Int J Mol Sci 2012 Nov 9;13(11):14606-22. Epub 2012 Nov 9.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 800, Taiwan.

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November 2012
8 Reads
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Alterations in NADPH oxidase expression and blood-brain barrier in bile duct ligation-treated young rats: effects of melatonin.

Neurochem Int 2012 Jun 4;60(8):751-8. Epub 2012 Apr 4.

Department of Pediatrics, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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June 2012
16 Reads
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Neonatal seizures: dialogues between clinic and bench.

J Formos Med Assoc 2012 May 7;111(5):239-44. Epub 2012 Apr 7.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, 123 Ta-Pei Road, Niao Sung, Kaohsiung 833, Taiwan.

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May 2012
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Arginine and asymmetric dimethylarginine in puromycin aminonucleoside-induced chronic kidney disease in the rat.

Am J Nephrol 2012 15;35(1):40-8. Epub 2011 Dec 15.

Department of Physiology and Functional Genomics, University of Florida, Gainesville, USA.

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May 2012
15 Reads
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Endotoxemia exacerbates kidney injury and increases asymmetric dimethylarginine in young bile duct-ligated rats.

Shock 2012 Apr;37(4):441-8

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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April 2012
38 Reads
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The combined ratios of L-arginine and asymmetric and symmetric dimethylarginine as biomarkers in spontaneously hypertensive rats.

Transl Res 2012 Feb 29;159(2):90-8. Epub 2011 Sep 29.

Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, 123 Dabi Rd., Niausung, Kaohsiung 833, Taiwan.

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February 2012
46 Reads
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Melatonin utility in neonates and children.

J Formos Med Assoc 2012 Feb 15;111(2):57-66. Epub 2012 Feb 15.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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February 2012
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Apocynin attenuates oxidative stress and hypertension in young spontaneously hypertensive rats independent of ADMA/NO pathway.

Free Radic Res 2012 Jan 29;46(1):68-76. Epub 2011 Nov 29.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.

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http://dx.doi.org/10.3109/10715762.2011.639069DOI Listing
January 2012
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Aliskiren prevents hypertension and reduces asymmetric dimethylarginine in young spontaneously hypertensive rats.

Eur J Pharmacol 2011 Nov 21;670(2-3):561-5. Epub 2011 Sep 21.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1016/j.ejphar.2011.09.005DOI Listing
November 2011
22 Reads
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Identification of immunodeficient molecules in neonatal mononuclear cells by proteomic differential displays.

Proteomics 2011 Sep 4;11(17):3491-500. Epub 2011 Aug 4.

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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September 2011
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Glyceraldehyde-3-phosphate dehydrogenase is a reliable internal control in Western blot analysis of leukocyte subpopulations from children.

Anal Biochem 2011 Jun 1;413(1):24-9. Epub 2011 Feb 1.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.1016/j.ab.2011.01.037DOI Listing
June 2011
15 Reads
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Reciprocal changes of renal neuronal nitric oxide synthase-α and -β associated with renal progression in a neonatal 5/6 nephrectomized rat model.

Pediatr Neonatol 2011 Apr 16;52(2):66-72. Epub 2011 Mar 16.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University, College of Medicine, Taiwan.

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April 2011
14 Reads
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Ectopic pelvic kidney with urinary tract infection presenting as lower abdominal pain in a child.

Pediatr Neonatol 2011 Apr 29;52(2):117-20. Epub 2011 Mar 29.

Department of Pediatrics, Fooyin University Hospital, Kaohsiung, Taiwan.

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April 2011
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Chronic nitric oxide deficiency and progression of kidney disease after renal mass reduction in the C57Bl6 mouse.

Am J Nephrol 2010 11;32(6):575-80. Epub 2010 Nov 11.

Department of Pulmonology, Semmelweis University, Budapest, Hungary.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992651PMC
April 2011
24 Reads
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Carbon dioxide pneumoperitoneum induces anti-inflammatory response and hepatic oxidative stress in young rats with bacterial peritonitis.

Pediatr Surg Int 2011 Mar 26;27(3):289-94. Epub 2010 Nov 26.

Department of Pediatric Surgery, Pingtung Christian Hospital, Pingtung, Taiwan.

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http://dx.doi.org/10.1007/s00383-010-2801-4DOI Listing
March 2011
22 Reads
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Asymmetric dimethylarginine: clinical applications in pediatric medicine.

J Formos Med Assoc 2011 Feb;110(2):70-7

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, College of Medicine, Chang Gung University, 123 Dabi Road, Kaohsiung, Taiwan.

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February 2011
10 Reads
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Urachal catheter provides new choice for long-term urinary diversion in prune belly syndrome.

Urology 2011 Feb 30;77(2):466-8. Epub 2010 Aug 30.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1016/j.urology.2010.05.028DOI Listing
February 2011
14 Reads
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Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats.

J Pineal Res 2010 Nov 9;49(4):390-8. Epub 2010 Sep 9.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University, College of Medicine, Taiwan.

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http://dx.doi.org/10.1111/j.1600-079X.2010.00806.xDOI Listing
November 2010
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Reduced brain content of arachidonic acid and docosahexaenoic acid is related to the severity of liver fibrosis.

Dig Dis Sci 2010 Oct 26;55(10):2831-7. Epub 2010 Jan 26.

Pediatrics Department, Chang-Gung Memorial Hospital-Kaohsiung Medical Center, Chang-Gung University College of Medicine, Niao Song, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1007/s10620-009-1120-xDOI Listing
October 2010
24 Reads
2 Citations
2.550 Impact Factor

Melatonin blocks oxidative stress-induced increased asymmetric dimethylarginine.

Free Radic Biol Med 2010 Sep 1;49(6):1088-98. Epub 2010 Jul 1.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.1016/j.freeradbiomed.2010.06.029DOI Listing
September 2010
38 Reads
17 Citations
5.740 Impact Factor

Bile duct ligation in developing rats: temporal progression of liver, kidney, and brain damage.

J Pediatr Surg 2010 Aug;45(8):1650-8

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University, College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.1016/j.jpedsurg.2009.12.019DOI Listing
August 2010
50 Reads
10 Citations
1.310 Impact Factor

Effects of maternal L-citrulline supplementation on renal function and blood pressure in offspring exposed to maternal caloric restriction: the impact of nitric oxide pathway.

Nitric Oxide 2010 Aug 4;23(1):34-41. Epub 2010 Apr 4.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University, College of Medicine, Taiwan.

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http://dx.doi.org/10.1016/j.niox.2010.03.005DOI Listing
August 2010
13 Reads
18 Citations
3.520 Impact Factor

Melatonin prevents increased asymmetric dimethylarginine in young rats with bile duct ligation.

J Pineal Res 2010 Apr 23;48(3):212-21. Epub 2010 Feb 23.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University, Taiwan.

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http://dx.doi.org/10.1111/j.1600-079X.2010.00745.xDOI Listing
April 2010
24 Reads
12 Citations
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The interaction between high ammonia diet and bile duct ligation in developing rats: assessment by spatial memory and asymmetric dimethylarginine.

Int J Dev Neurosci 2010 Apr 24;28(2):169-74. Epub 2009 Nov 24.

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.1016/j.ijdevneu.2009.11.006DOI Listing
April 2010
14 Reads
11 Citations
2.580 Impact Factor

Splice variants of neuronal nitric oxide synthase are present in the rat kidney.

Smith C, Merchant M, Fekete A, Nyugen HL, Oh P, Tain YL, Klein JB, Baylis C, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, vol. 24, no. 5, pp. 1422-1428, 2009

http://europepmc.org/abstract/med/19073653

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May 2009
11 Reads

Splice variants of neuronal nitric oxide synthase are present in the rat kidney.

Nephrol Dial Transplant 2009 May 10;24(5):1422-8. Epub 2008 Dec 10.

Department of Physiology and Functional Genomics, University of Florida, POB 100274, Gainesville, FL 36210, USA.

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http://dx.doi.org/10.1093/ndt/gfn676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721461PMC
May 2009
17 Reads
25 Citations
3.580 Impact Factor

Melatonin ameliorates bile duct ligation-induced systemic oxidative stress and spatial memory deficits in developing rats.

Pediatr Res 2009 Feb;65(2):176-80

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

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http://dx.doi.org/10.1203/PDR.0b013e31818d5bc7DOI Listing
February 2009
56 Reads
11 Citations
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Sex differences in response to cyclosporine immunosuppression in experimental kidney transplantation.

Muller V, Szabo AJ, Erdely A, Tain YL, Baylis C, Clinical and experimental pharmacology & physiology, 2008, vol. 35, no. 5-6, pp. 574-579, 2008

http://europepmc.org/abstract/med/18070141

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May 2008
10 Reads

Sex differences in response to cyclosporine immunosuppression in experimental kidney transplantation.

Clin Exp Pharmacol Physiol 2008 May 7;35(5-6):574-9. Epub 2007 Dec 7.

Department of Pulmonology, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1111/j.1440-1681.2007.04841.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757285PMC
May 2008
35 Reads
3 Citations

Endothelial dysfunction links cardiovascular disease to pediatric chronic kidney disease: the role of nitric oxide deficiency.

Authors:
You-Lin Tain

Acta Paediatr Taiwan 2007 Sep-Oct;48(5):246-50

Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University, College of Medicine, Niausung,Taoyuan, Taiwan.

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February 2008
20 Reads

Renal cortex neuronal nitric oxide synthase in response to rapamycin in kidney transplantation.

Nitric Oxide 2008 Feb 12;18(1):80-6. Epub 2007 Oct 12.

Department of Physiology and Functional Genomics, 1600 SW Archer Road, Room M544, University of Florida, POB 100274, Gainesville, FI 32667, USA.

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http://dx.doi.org/10.1016/j.niox.2007.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247710PMC
February 2008
17 Reads
10 Citations

Determination of dimethylarginine dimethylaminohydrolase activity in the kidney.

Authors:
Tain YL Baylis C

Tain YL, Baylis C, Kidney international, 2007, vol. 72, no. 7, pp. 886-889, 2007

http://europepmc.org/abstract/med/17653133

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October 2007
12 Reads

Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat.

Am J Physiol Renal Physiol 2007 May 2;292(5):F1404-10. Epub 2007 Jan 2.

Department of Physiology and Functional Genomics, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1152/ajprenal.00260.2006DOI Listing
May 2007
16 Reads
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DOCA/NaCl-induced chronic kidney disease: a comparison of renal nitric oxide production in resistant and susceptible rat strains.

Am J Physiol Renal Physiol 2007 Jan 8;292(1):F192-6. Epub 2006 Aug 8.

Department of Physiology and Pharmacology, West Virginia University, USA.

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http://dx.doi.org/10.1152/ajprenal.00146.2006DOI Listing
January 2007
19 Reads
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Lack of long-term protective effect of antioxidant/anti-inflammatory therapy in transplant-induced ischemia/reperfusion injury.

Am J Nephrol 2006 24;26(3):213-7. Epub 2006 May 24.

Department of Physiology and Functional Genomics, University of Florida, Gainesville, FL 32611, USA.

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http://dx.doi.org/10.1159/000093587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756816PMC
November 2006
32 Reads
4 Citations

Dissecting the causes of oxidative stress in an in vivo model of hypertension.

Hypertension 2006 Nov 2;48(5):828-9. Epub 2006 Oct 2.

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http://dx.doi.org/10.1161/01.HYP.0000242927.24428.25DOI Listing
November 2006
15 Reads
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Diffuse xanthogranulomatous pyelonephritis and staghorn calculus: report of one case.

Acta Paediatr Taiwan 2004 Jan-Feb;45(1):45-7

Department of Pediatrics, Chang Gung Memorial Hospital at Kaohsiung, Taiwan.

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August 2004
17 Reads
1 Citation

Implication of serum IgE in childhood nephrotic syndrome.

Pediatr Nephrol 2003 Dec 31;18(12):1211-5. Epub 2003 Oct 31.

Division of Pediatric Nephrology, Chang Gung Children's Hospital, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1007/s00467-003-1269-zDOI Listing
December 2003
8 Reads
4 Citations

Renal pelvic wall thickening in childhood urinary tract infections--evidence of acute pyelitis or vesicoureteral reflux?

Authors:
You-Lin Tain

Scand J Urol Nephrol 2003 ;37(1):28-30

Division of Pediatric Nephrology, Chang Gung Memorial Hospital at Kaohsiung, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1080/00365590310008640DOI Listing
June 2003
13 Reads
1 Citation

Implications of serum TNF-beta and IL-13 in the treatment response of childhood nephrotic syndrome.

Cytokine 2003 Feb;21(3):155-9

Division of Pediatric Nephrology, Department of Pediatrics, Chang Gung Children's Hospital, Kaohsiung, Taiwan, ROC

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http://dx.doi.org/10.1016/s1043-4666(03)00017-6DOI Listing
February 2003
17 Reads
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Implications of blood soluble and cell surface tumor necrosis factor receptors in childhood nephrotic syndrome.

Pediatr Nephrol 2002 Nov 29;17(11):926-32. Epub 2002 Oct 29.

Division of Pediatric Nephrology, Chang Gung Children's Hospital, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1007/s00467-002-0994-zDOI Listing
November 2002
12 Reads

Thalamic stroke secondary to straight sinus thrombosis in a nephrotic child.

Pediatr Nephrol 2002 Mar;17(3):184-6

Department of Pediatrics, Division of Pediatric Nephrology, Chang Gung Memorial Hospital at Kaohsiung, 123 Ta-Pei Road, Niao-Sung Hsiang, Kaohsiung Hsien, Taiwan, Republic of China.

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http://dx.doi.org/10.1007/s00467-001-0785-yDOI Listing
March 2002
19 Reads
1 Citation