Yotis A Senis

Yotis A Senis

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Yotis A Senis

Yotis A Senis

Publications by authors named "Yotis A Senis"

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Collagen type I degradation fragments act through the collagen receptor LAIR-1 to provide a negative feedback for osteoclast formation.

Bone 2018 12 12;117:23-30. Epub 2018 Sep 12.

Faculty of Dentistry, McGill University, Montreal, Quebec, Canada; Shriners Hospital for Children-Canada, Montreal, Quebec H3G 1A6, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S87563282183034
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http://dx.doi.org/10.1016/j.bone.2018.09.006DOI Listing
December 2018

TLT-1: please release me, let me go.

Authors:
Yotis A Senis

Blood 2018 12;132(23):2427-2429

University of Birmingham.

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http://dx.doi.org/10.1182/blood-2018-10-879676DOI Listing
December 2018

Signalling through Src family kinase isoforms is not redundant in models of thrombo-inflammatory vascular disease.

J Cell Mol Med 2018 09 4;22(9):4317-4327. Epub 2018 Jul 4.

Institute of Cardiovascular Sciences, College of Medical and Dental Science, The Medical School, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1111/jcmm.13721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111872PMC
September 2018

TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice.

Blood Adv 2018 08;2(16):2072-2078

Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1182/bloodadvances.2018017756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113608PMC
August 2018

Targeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?

Molecules 2018 Mar 2;23(3). Epub 2018 Mar 2.

Department of Biomedical Science, Faculty of Science and Technology, University of Westminster, London W1W 6UW, UK.

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http://dx.doi.org/10.3390/molecules23030569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017057PMC
March 2018

ITIM receptors: more than just inhibitors of platelet activation.

Blood 2017 06 2;129(26):3407-3418. Epub 2017 May 2.

Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1182/blood-2016-12-720185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562394PMC
June 2017

Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets.

Arterioscler Thromb Vasc Biol 2017 05 23;37(5):823-835. Epub 2017 Mar 23.

From the Institute of Cardiovascular Sciences, College of Medical and Dental Sciences (C.W.S., S.G.T., Z.R., P.P., M.B., M.L., Y.A.S., S.P.W., A.M.), and Institute of Applied Health Research, College of Medical and Dental Sciences (D.B.), University of Birmingham, United Kingdom; and Laboratory of Translational Immunology, Department of Immunology, University Medical Center Utrecht, the Netherlands (L.M.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309253DOI Listing
May 2017

Ups and downs of the ADP phosphoproteome.

Blood 2017 01;129(2):135-136

UNIVERSITY OF BIRMINGHAM.

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http://dx.doi.org/10.1182/blood-2016-11-751917DOI Listing
January 2017

Cross talk between serine/threonine and tyrosine kinases regulates ADP-induced thromboxane generation in platelets.

Thromb Haemost 2015 Aug 7;114(3):558-68. Epub 2015 May 7.

Satya P. Kunapuli PhD, Department of Physiology and Sol Sherry Thrombosis Center,, Temple University School of Medicine,, 3420 North Broad street, MRB 414, Philadelphia PA, 19140, USA, Tel.: +1 215 707 4615, Fax: +1 215 707 6944, E-mail:

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http://dx.doi.org/10.1160/TH14-09-0775DOI Listing
August 2015

Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy.

Bioorg Med Chem 2015 Jun 4;23(12):2786-97. Epub 2015 Apr 4.

Immunology and Infectious Diseases Unit, GIGA-Signal Transduction, University of Liège, Liège, Belgium.

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http://dx.doi.org/10.1016/j.bmc.2015.03.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451376PMC
June 2015

Proplatelets slip slidin' away.

Blood 2015 Jan;125(5):747-8

UNIVERSITY OF BIRMINGHAM.

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http://dx.doi.org/10.1182/blood-2014-12-614131DOI Listing
January 2015

Src family kinases: at the forefront of platelet activation.

Blood 2014 Sep 12;124(13):2013-24. Epub 2014 Aug 12.

Centre for Cardiovascular Sciences, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

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http://www.bloodjournal.org/content/124/13/2013.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-01-45
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http://dx.doi.org/10.1182/blood-2014-01-453134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186533PMC
September 2014

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function.

Blood 2013 May 18;121(20):4205-20. Epub 2013 Mar 18.

Centre for Cardiovascular Sciences, School of Clinical and Experimental Medicine, Institute of Biomedical Research, University of Birmingham, United Kingdom.

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http://dx.doi.org/10.1182/blood-2012-08-449272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656453PMC
May 2013

Dominant role of the protein-tyrosine phosphatase CD148 in regulating platelet activation relative to protein-tyrosine phosphatase-1B.

Arterioscler Thromb Vasc Biol 2012 Dec 11;32(12):2956-65. Epub 2012 Oct 11.

Centre for Cardiovascular Sciences, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1161/ATVBAHA.112.300447DOI Listing
December 2012

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function.

Sci Signal 2012 Oct 30;5(248):ra78. Epub 2012 Oct 30.

Centre of Cardiovascular Sciences, Institute of Biomedical Research, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1126/scisignal.2002936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973664PMC
October 2012

Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling.

J Biol Chem 2011 Feb 22;286(6):4107-16. Epub 2010 Nov 22.

Centre for Cardiovascular Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M110.167502
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http://dx.doi.org/10.1074/jbc.M110.167502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039337PMC
February 2011

G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2.

J Biol Chem 2008 Dec 27;283(51):35419-27. Epub 2008 Oct 27.

Centre for Cardiovascular Sciences, Institute of Biomedical Research, University of Birmingham, B15 2TT, UK.

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http://dx.doi.org/10.1074/jbc.M806895200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602894PMC
December 2008

Minimal regulation of platelet activity by PECAM-1.

Platelets 2007 Feb;18(1):56-67

Centre for Cardiovascular Sciences, Institute of Biomedical Research, Division of Medical Sciences, The Medical School, University of Birmingham, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1080/09537100600881396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828610PMC
February 2007

Isolation and characterization of cotiaractivase, a novel low molecular weight prothrombin activator from the venom of Bothrops cotiara.

Biochim Biophys Acta 2006 May 7;1764(5):863-71. Epub 2006 Apr 7.

Centre for Cardiovascular Sciences, Institute of Biomedical Research, University of Birmingham, Wolfson Drive, Edgbaston, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1016/j.bbapap.2006.03.004DOI Listing
May 2006

Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets.

Platelets 2005 May-Jun;16(3-4):191-202

Centre for Cardiovascular Sciences, Division of Medical Sciences, Institute of Biomedical Research, Wolfson Drive, The Medical School, University of Birmingham, Edgbaston, Birmingham, UK.

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http://dx.doi.org/10.1080/09537100400016711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868960PMC
October 2005

Adhesion of human and mouse platelets to collagen under shear: a unifying model.

FASEB J 2005 May 9;19(7):825-7. Epub 2005 Mar 9.

Centre for Cardiovascular Sciences, Division of Medical Sciences, Institute of Biomedical Research, The Medical School, University of Birmingham, Edgbaston, Birmingham, UK.

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http://dx.doi.org/10.1096/fj.04-1940fjeDOI Listing
May 2005

Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen.

J Biol Chem 2004 Dec 27;279(52):53955-62. Epub 2004 Sep 27.

Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.

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http://dx.doi.org/10.1074/jbc.M410355200DOI Listing
December 2004

GPVI levels in platelets: relationship to platelet function at high shear.

Blood 2003 Oct 26;102(8):2811-8. Epub 2003 Jun 26.

Department of Pharmacology, Oxford University, Mansfield Rd, Oxford, OX1 3QT, United Kingdom.

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http://dx.doi.org/10.1182/blood-2003-01-0231DOI Listing
October 2003

Fps/Fes and Fer protein-tyrosinekinases play redundant roles in regulating hematopoiesis.

Exp Hematol 2003 Aug;31(8):673-81

Department of Pathology, Queen's University, Kingston, Ontario, Canada.

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August 2003

Absence of Fer protein-tyrosine kinase exacerbates leukocyte recruitment in response to endotoxin.

J Immunol 2002 May;168(10):4930-5

Immunology Research Group, Department of Medical Physiology, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.

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http://dx.doi.org/10.4049/jimmunol.168.10.4930DOI Listing
May 2002