Publications by authors named "Yoshinori Yamanishi"

39 Publications

Skin-infiltrating basophils promote atopic dermatitis-like inflammation via IL-4 production in mice.

Allergy 2020 10 26;75(10):2613-2622. Epub 2020 May 26.

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

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October 2020

Pivotal role of STIM2, but not STIM1, in IL-4 production by IL-3-stimulated murine basophils.

Sci Signal 2019 04 9;12(576). Epub 2019 Apr 9.

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.

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April 2019

Basophils trigger emphysema development in a murine model of COPD through IL-4-mediated generation of MMP-12-producing macrophages.

Proc Natl Acad Sci U S A 2018 12 3;115(51):13057-13062. Epub 2018 Dec 3.

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan;

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December 2018

Aggregation makes a protein allergenic at the challenge phase of basophil-mediated allergy in mice.

Int Immunol 2019 02;31(1):41-49

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, Japan.

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February 2019

How do basophils contribute to Th2 cell differentiation and allergic responses?

Int Immunol 2018 08;30(9):391-396

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan.

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August 2018

Multifaceted roles of basophils in health and disease.

J Allergy Clin Immunol 2018 08 14;142(2):370-380. Epub 2017 Dec 14.

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

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August 2018

Differential usage of COX-1 and COX-2 in prostaglandin production by mast cells and basophils.

Biochem Biophys Rep 2017 Jul 15;10:82-87. Epub 2017 Mar 15.

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan.

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July 2017

Recent advances in understanding basophil-mediated Th2 immune responses.

Immunol Rev 2017 07;278(1):237-245

Department of Immune Regulation, Tokyo Medical and Dental University (TMDU), Graduate School of Medical and Dental Sciences, Tokyo, Japan.

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July 2017

Trogocytosis of peptide-MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils.

Proc Natl Acad Sci U S A 2017 01 17;114(5):1111-1116. Epub 2017 Jan 17.

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan

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January 2017

The Basophil-specific Protease mMCP-8 Provokes an Inflammatory Response in the Skin with Microvascular Hyperpermeability and Leukocyte Infiltration.

J Biol Chem 2017 01 8;292(3):1061-1067. Epub 2016 Dec 8.

From the Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8519, Japan.

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January 2017

Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands of inhibitory receptor CD200R.

Sci Rep 2016 11 7;6:36457. Epub 2016 Nov 7.

Department of Immune Regulation, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

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November 2016

Basophil tryptase mMCP-11 plays a crucial role in IgE-mediated, delayed-onset allergic inflammation in mice.

Blood 2016 12 27;128(25):2909-2918. Epub 2016 Oct 27.

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

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December 2016

Real-time imaging of mast cell degranulation in vitro and in vivo.

Biochem Biophys Res Commun 2016 Oct 21;479(3):517-522. Epub 2016 Sep 21.

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.

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October 2016

Basophils and mast cells in immunity and inflammation.

Semin Immunopathol 2016 09 12;38(5):535-7. Epub 2016 Jul 12.

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.

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September 2016

Basophil-derived IL-4 plays versatile roles in immunity.

Semin Immunopathol 2016 09 10;38(5):615-22. Epub 2016 May 10.

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.

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September 2016

MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice.

Blood 2016 05 22;127(21):2607-17. Epub 2016 Mar 22.

Division of Molecular Bioregulation, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan;

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May 2016

Large particulate allergens can elicit mast cell-mediated anaphylaxis without exit from blood vessels as efficiently as do small soluble allergens.

Biochem Biophys Res Commun 2015 Nov 26;467(1):70-5. Epub 2015 Sep 26.

Department of Immune Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan. Electronic address:

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November 2015

Ceramide-CD300f binding suppresses experimental colitis by inhibiting ATP-mediated mast cell activation.

Gut 2016 May 11;65(5):777-87. Epub 2015 Feb 11.

Division of Cellular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan Atopy Research Center, Juntendo University School of Medicine, Tokyo, Japan.

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May 2016

Basophils have emerged as a key player in immunity.

Curr Opin Immunol 2014 Dec 5;31:1-7. Epub 2014 Aug 5.

Department of Immune Regulation, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Tokyo 113-8519, Japan.

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December 2014

Sphingomyelin and ceramide are physiological ligands for human LMIR3/CD300f, inhibiting FcεRI-mediated mast cell activation.

J Allergy Clin Immunol 2014 Jan 12;133(1):270-3.e1-7. Epub 2013 Sep 12.

Division of Cellular Therapy, The Institute of Medical Science, University of Tokyo, Tokyo, Japan. Electronic address:

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January 2014