Publications by authors named "Yoshinori Murakami"

100Publications

The Polygenic and Monogenic Basis of Blood Traits and Diseases.

Authors:
Dragana Vuckovic Erik L Bao Parsa Akbari Caleb A Lareau Abdou Mousas Tao Jiang Ming-Huei Chen Laura M Raffield Manuel Tardaguila Jennifer E Huffman Scott C Ritchie Karyn Megy Hannes Ponstingl Christopher J Penkett Patrick K Albers Emilie M Wigdor Saori Sakaue Arden Moscati Regina Manansala Ken Sin Lo Huijun Qian Masato Akiyama Traci M Bartz Yoav Ben-Shlomo Andrew Beswick Jette Bork-Jensen Erwin P Bottinger Jennifer A Brody Frank J A van Rooij Kumaraswamy N Chitrala Peter W F Wilson Hélène Choquet John Danesh Emanuele Di Angelantonio Niki Dimou Jingzhong Ding Paul Elliott Tõnu Esko Michele K Evans Stephan B Felix James S Floyd Linda Broer Niels Grarup Michael H Guo Qi Guo Andreas Greinacher Jeff Haessler Torben Hansen Joanna M M Howson Wei Huang Eric Jorgenson Tim Kacprowski Mika Kähönen Yoichiro Kamatani Masahiro Kanai Savita Karthikeyan Fotios Koskeridis Leslie A Lange Terho Lehtimäki Allan Linneberg Yongmei Liu Leo-Pekka Lyytikäinen Ani Manichaikul Koichi Matsuda Karen L Mohlke Nina Mononen Yoshinori Murakami Girish N Nadkarni Kjell Nikus Nathan Pankratz Oluf Pedersen Michael Preuss Bruce M Psaty Olli T Raitakari Stephen S Rich Benjamin A T Rodriguez Jonathan D Rosen Jerome I Rotter Petra Schubert Cassandra N Spracklen Praveen Surendran Hua Tang Jean-Claude Tardif Mohsen Ghanbari Uwe Völker Henry Völzke Nicholas A Watkins Stefan Weiss Na Cai Kousik Kundu Stephen B Watt Klaudia Walter Alan B Zonderman Kelly Cho Yun Li Ruth J F Loos Julian C Knight Michel Georges Oliver Stegle Evangelos Evangelou Yukinori Okada David J Roberts Michael Inouye Andrew D Johnson Paul L Auer William J Astle Alexander P Reiner Adam S Butterworth Willem H Ouwehand Guillaume Lettre Vijay G Sankaran Nicole Soranzo

Cell 2020 Sep;182(5):1214-1231.e11

Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK; National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK; Department of Haematology, University of Cambridge, Cambridge, CB2 0PT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.08.008DOI Listing
September 2020

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

Authors:
Ming-Huei Chen Laura M Raffield Abdou Mousas Saori Sakaue Jennifer E Huffman Arden Moscati Bhavi Trivedi Tao Jiang Parsa Akbari Dragana Vuckovic Erik L Bao Xue Zhong Regina Manansala Véronique Laplante Minhui Chen Ken Sin Lo Huijun Qian Caleb A Lareau Mélissa Beaudoin Karen A Hunt Masato Akiyama Traci M Bartz Yoav Ben-Shlomo Andrew Beswick Jette Bork-Jensen Erwin P Bottinger Jennifer A Brody Frank J A van Rooij Kumaraswamynaidu Chitrala Kelly Cho Hélène Choquet Adolfo Correa John Danesh Emanuele Di Angelantonio Niki Dimou Jingzhong Ding Paul Elliott Tõnu Esko Michele K Evans James S Floyd Linda Broer Niels Grarup Michael H Guo Andreas Greinacher Jeff Haessler Torben Hansen Joanna M M Howson Qin Qin Huang Wei Huang Eric Jorgenson Tim Kacprowski Mika Kähönen Yoichiro Kamatani Masahiro Kanai Savita Karthikeyan Fotis Koskeridis Leslie A Lange Terho Lehtimäki Markus M Lerch Allan Linneberg Yongmei Liu Leo-Pekka Lyytikäinen Ani Manichaikul Hilary C Martin Koichi Matsuda Karen L Mohlke Nina Mononen Yoshinori Murakami Girish N Nadkarni Matthias Nauck Kjell Nikus Willem H Ouwehand Nathan Pankratz Oluf Pedersen Michael Preuss Bruce M Psaty Olli T Raitakari David J Roberts Stephen S Rich Benjamin A T Rodriguez Jonathan D Rosen Jerome I Rotter Petra Schubert Cassandra N Spracklen Praveen Surendran Hua Tang Jean-Claude Tardif Richard C Trembath Mohsen Ghanbari Uwe Völker Henry Völzke Nicholas A Watkins Alan B Zonderman Peter W F Wilson Yun Li Adam S Butterworth Jean-François Gauchat Charleston W K Chiang Bingshan Li Ruth J F Loos William J Astle Evangelos Evangelou David A van Heel Vijay G Sankaran Yukinori Okada Nicole Soranzo Andrew D Johnson Alexander P Reiner Paul L Auer Guillaume Lettre

Cell 2020 Sep;182(5):1198-1213.e14

Montreal Heart Institute, Montreal, QC H1T 1C8, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480402PMC
September 2020

Short somatic alterations at the site of copy number variation in breast cancer.

Cancer Sci 2020 Aug 29. Epub 2020 Aug 29.

Division of Molecular Pathology, The Institute of Medical Science, The University of Tokyo.

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http://dx.doi.org/10.1111/cas.14630DOI Listing
August 2020

Mint3 depletion restricts tumor malignancy of pancreatic cancer cells by decreasing SKP2 expression via HIF-1.

Oncogene 2020 Sep 21;39(39):6218-6230. Epub 2020 Aug 21.

Department of System Biology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Takaramachi, Kanazawa, Ishikawa, Japan.

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http://dx.doi.org/10.1038/s41388-020-01423-8DOI Listing
September 2020

CADM1 suppresses c-Src activation by binding with Cbp on membrane lipid rafts and intervenes colon carcinogenesis.

Biochem Biophys Res Commun 2020 Aug 29;529(3):854-860. Epub 2020 Jun 29.

Division of Molecular Pathology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.05.103DOI Listing
August 2020

Chromosomal alterations among age-related haematopoietic clones in Japan.

Nature 2020 08 24;584(7819):130-135. Epub 2020 Jun 24.

Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

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http://dx.doi.org/10.1038/s41586-020-2426-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489641PMC
August 2020

Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer.

Nat Commun 2020 06 24;11(1):3175. Epub 2020 Jun 24.

Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, 464-8681, Japan.

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http://dx.doi.org/10.1038/s41467-020-16711-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314803PMC
June 2020

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.

Nat Genet 2020 07 8;52(7):669-679. Epub 2020 Jun 8.

Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

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http://dx.doi.org/10.1038/s41588-020-0640-3DOI Listing
July 2020

Genetic and phenotypic landscape of the mitochondrial genome in the Japanese population.

Commun Biol 2020 Mar 5;3(1):104. Epub 2020 Mar 5.

Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.

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http://dx.doi.org/10.1038/s42003-020-0812-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058612PMC
March 2020

Associations of autozygosity with a broad range of human phenotypes.

Authors:
David W Clark Yukinori Okada Kristjan H S Moore Dan Mason Nicola Pirastu Ilaria Gandin Hannele Mattsson Catriona L K Barnes Kuang Lin Jing Hua Zhao Patrick Deelen Rebecca Rohde Claudia Schurmann Xiuqing Guo Franco Giulianini Weihua Zhang Carolina Medina-Gomez Robert Karlsson Yanchun Bao Traci M Bartz Clemens Baumbach Ginevra Biino Matthew J Bixley Marco Brumat Jin-Fang Chai Tanguy Corre Diana L Cousminer Annelot M Dekker David A Eccles Kristel R van Eijk Christian Fuchsberger He Gao Marine Germain Scott D Gordon Hugoline G de Haan Sarah E Harris Edith Hofer Alicia Huerta-Chagoya Catherine Igartua Iris E Jansen Yucheng Jia Tim Kacprowski Torgny Karlsson Marcus E Kleber Shengchao Alfred Li Ruifang Li-Gao Anubha Mahajan Koichi Matsuda Karina Meidtner Weihua Meng May E Montasser Peter J van der Most Matthias Munz Teresa Nutile Teemu Palviainen Gauri Prasad Rashmi B Prasad Tallapragada Divya Sri Priyanka Federica Rizzi Erika Salvi Bishwa R Sapkota Daniel Shriner Line Skotte Melissa C Smart Albert Vernon Smith Ashley van der Spek Cassandra N Spracklen Rona J Strawbridge Salman M Tajuddin Stella Trompet Constance Turman Niek Verweij Clara Viberti Lihua Wang Helen R Warren Robyn E Wootton Lisa R Yanek Jie Yao Noha A Yousri Wei Zhao Adebowale A Adeyemo Saima Afaq Carlos Alberto Aguilar-Salinas Masato Akiyama Matthew L Albert Matthew A Allison Maris Alver Tin Aung Fereidoun Azizi Amy R Bentley Heiner Boeing Eric Boerwinkle Judith B Borja Gert J de Borst Erwin P Bottinger Linda Broer Harry Campbell Stephen Chanock Miao-Li Chee Guanjie Chen Yii-Der I Chen Zhengming Chen Yen-Feng Chiu Massimiliano Cocca Francis S Collins Maria Pina Concas Janie Corley Giovanni Cugliari Rob M van Dam Anna Damulina Maryam S Daneshpour Felix R Day Graciela E Delgado Klodian Dhana Alexander S F Doney Marcus Dörr Ayo P Doumatey Nduna Dzimiri S Sunna Ebenesersdóttir Joshua Elliott Paul Elliott Ralf Ewert Janine F Felix Krista Fischer Barry I Freedman Giorgia Girotto Anuj Goel Martin Gögele Mark O Goodarzi Mariaelisa Graff Einat Granot-Hershkovitz Francine Grodstein Simonetta Guarrera Daniel F Gudbjartsson Kamran Guity Bjarni Gunnarsson Yu Guo Saskia P Hagenaars Christopher A Haiman Avner Halevy Tamara B Harris Mehdi Hedayati David A van Heel Makoto Hirata Imo Höfer Chao Agnes Hsiung Jinyan Huang Yi-Jen Hung M Arfan Ikram Anuradha Jagadeesan Pekka Jousilahti Yoichiro Kamatani Masahiro Kanai Nicola D Kerrison Thorsten Kessler Kay-Tee Khaw Chiea Chuen Khor Dominique P V de Kleijn Woon-Puay Koh Ivana Kolcic Peter Kraft Bernhard K Krämer Zoltán Kutalik Johanna Kuusisto Claudia Langenberg Lenore J Launer Deborah A Lawlor I-Te Lee Wen-Jane Lee Markus M Lerch Liming Li Jianjun Liu Marie Loh Stephanie J London Stephanie Loomis Yingchang Lu Jian'an Luan Reedik Mägi Ani W Manichaikul Paolo Manunta Gísli Másson Nana Matoba Xue W Mei Christa Meisinger Thomas Meitinger Massimo Mezzavilla Lili Milani Iona Y Millwood Yukihide Momozawa Amy Moore Pierre-Emmanuel Morange Hortensia Moreno-Macías Trevor A Mori Alanna C Morrison Taulant Muka Yoshinori Murakami Alison D Murray Renée de Mutsert Josyf C Mychaleckyj Mike A Nalls Matthias Nauck Matt J Neville Ilja M Nolte Ken K Ong Lorena Orozco Sandosh Padmanabhan Gunnar Pálsson James S Pankow Cristian Pattaro Alison Pattie Ozren Polasek Neil Poulter Peter P Pramstaller Lluis Quintana-Murci Katri Räikkönen Sarju Ralhan Dabeeru C Rao Wouter van Rheenen Stephen S Rich Paul M Ridker Cornelius A Rietveld Antonietta Robino Frank J A van Rooij Daniela Ruggiero Yasaman Saba Charumathi Sabanayagam Maria Sabater-Lleal Cinzia Felicita Sala Veikko Salomaa Kevin Sandow Helena Schmidt Laura J Scott William R Scott Bahareh Sedaghati-Khayat Bengt Sennblad Jessica van Setten Peter J Sever Wayne H-H Sheu Yuan Shi Smeeta Shrestha Sharvari Rahul Shukla Jon K Sigurdsson Timo Tonis Sikka Jai Rup Singh Blair H Smith Alena Stančáková Alice Stanton John M Starr Lilja Stefansdottir Leon Straker Patrick Sulem Gardar Sveinbjornsson Morris A Swertz Adele M Taylor Kent D Taylor Natalie Terzikhan Yih-Chung Tham Gudmar Thorleifsson Unnur Thorsteinsdottir Annika Tillander Russell P Tracy Teresa Tusié-Luna Ioanna Tzoulaki Simona Vaccargiu Jagadish Vangipurapu Jan H Veldink Veronique Vitart Uwe Völker Eero Vuoksimaa Salma M Wakil Melanie Waldenberger Gurpreet S Wander Ya Xing Wang Nicholas J Wareham Sarah Wild Chittaranjan S Yajnik Jian-Min Yuan Lingyao Zeng Liang Zhang Jie Zhou Najaf Amin Folkert W Asselbergs Stephan J L Bakker Diane M Becker Benjamin Lehne David A Bennett Leonard H van den Berg Sonja I Berndt Dwaipayan Bharadwaj Lawrence F Bielak Murielle Bochud Mike Boehnke Claude Bouchard Jonathan P Bradfield Jennifer A Brody Archie Campbell Shai Carmi Mark J Caulfield David Cesarini John C Chambers Giriraj Ratan Chandak Ching-Yu Cheng Marina Ciullo Marilyn Cornelis Daniele Cusi George Davey Smith Ian J Deary Rajkumar Dorajoo Cornelia M van Duijn David Ellinghaus Jeanette Erdmann Johan G Eriksson Evangelos Evangelou Michele K Evans Jessica D Faul Bjarke Feenstra Mary Feitosa Sylvain Foisy Andre Franke Yechiel Friedlander Paolo Gasparini Christian Gieger Clicerio Gonzalez Philippe Goyette Struan F A Grant Lyn R Griffiths Leif Groop Vilmundur Gudnason Ulf Gyllensten Hakon Hakonarson Anders Hamsten Pim van der Harst Chew-Kiat Heng Andrew A Hicks Hagit Hochner Heikki Huikuri Steven C Hunt Vincent W V Jaddoe Philip L De Jager Magnus Johannesson Åsa Johansson Jost B Jonas J Wouter Jukema Juhani Junttila Jaakko Kaprio Sharon L R Kardia Fredrik Karpe Meena Kumari Markku Laakso Sander W van der Laan Jari Lahti Matthias Laudes Rodney A Lea Wolfgang Lieb Thomas Lumley Nicholas G Martin Winfried März Giuseppe Matullo Mark I McCarthy Sarah E Medland Tony R Merriman Andres Metspalu Brian F Meyer Karen L Mohlke Grant W Montgomery Dennis Mook-Kanamori Patricia B Munroe Kari E North Dale R Nyholt Jeffery R O'connell Carole Ober Albertine J Oldehinkel Walter Palmas Colin Palmer Gerard G Pasterkamp Etienne Patin Craig E Pennell Louis Perusse Patricia A Peyser Mario Pirastu Tinca J C Polderman David J Porteous Danielle Posthuma Bruce M Psaty John D Rioux Fernando Rivadeneira Charles Rotimi Jerome I Rotter Igor Rudan Hester M Den Ruijter Dharambir K Sanghera Naveed Sattar Reinhold Schmidt Matthias B Schulze Heribert Schunkert Robert A Scott Alan R Shuldiner Xueling Sim Neil Small Jennifer A Smith Nona Sotoodehnia E-Shyong Tai Alexander Teumer Nicholas J Timpson Daniela Toniolo David-Alexandre Tregouet Tiinamaija Tuomi Peter Vollenweider Carol A Wang David R Weir John B Whitfield Cisca Wijmenga Tien-Yin Wong John Wright Jingyun Yang Lei Yu Babette S Zemel Alan B Zonderman Markus Perola Patrik K E Magnusson André G Uitterlinden Jaspal S Kooner Daniel I Chasman Ruth J F Loos Nora Franceschini Lude Franke Chris S Haley Caroline Hayward Robin G Walters John R B Perry Tōnu Esko Agnar Helgason Kari Stefansson Peter K Joshi Michiaki Kubo James F Wilson

Nat Commun 2019 10 31;10(1):4957. Epub 2019 Oct 31.

Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland.

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http://dx.doi.org/10.1038/s41467-019-12283-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823371PMC
October 2019

Comparison of effects of UGT1A1*6 and UGT1A1*28 on irinotecan-induced adverse reactions in the Japanese population: analysis of the Biobank Japan Project.

J Hum Genet 2019 Dec 4;64(12):1195-1202. Epub 2019 Oct 4.

Laboratory for Pharmacogenomics, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.

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http://dx.doi.org/10.1038/s10038-019-0677-2DOI Listing
December 2019

Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population.

Eur J Hum Genet 2020 Mar 26;28(3):378-382. Epub 2019 Sep 26.

Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.

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http://dx.doi.org/10.1038/s41431-019-0518-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028931PMC
March 2020

GWAS of five gynecologic diseases and cross-trait analysis in Japanese.

Eur J Hum Genet 2020 01 5;28(1):95-107. Epub 2019 Sep 5.

Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.

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http://dx.doi.org/10.1038/s41431-019-0495-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906293PMC
January 2020

A case of an elderly patient with high-grade colorectal cancer in poor general condition who showed near complete response to chemotherapy and achieved long-term survival.

Int J Surg Case Rep 2019 22;58:186-189. Epub 2019 Mar 22.

Division of Molecular Pathology, The Institute of Medical Science, The University of Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ijscr.2019.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503123PMC
March 2019

Mathematical analysis of gefitinib resistance of lung adenocarcinoma caused by MET amplification.

Biochem Biophys Res Commun 2019 04 26;511(3):544-550. Epub 2019 Feb 26.

Division of Molecular Pathology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.02.086DOI Listing
April 2019

Expression profile of CADM1 and CADM4 in triple negative breast cancer with primary systemic therapy.

Oncol Lett 2019 Jan 19;17(1):921-926. Epub 2018 Nov 19.

Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima, Fukushima 960-1295, Japan.

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http://dx.doi.org/10.3892/ol.2018.9727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313031PMC
January 2019

Decreased expression of CADM1 and CADM4 are associated with advanced stage breast cancer.

Oncol Lett 2018 Feb 6;15(2):2401-2406. Epub 2017 Dec 6.

Department of Organ Regulatory Surgery, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan.

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http://dx.doi.org/10.3892/ol.2017.7536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777359PMC
February 2018

Characterization of KIF11 as a novel prognostic biomarker and therapeutic target for oral cancer.

Int J Oncol 2018 Jan 31;52(1):155-165. Epub 2017 Oct 31.

Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science Hospital, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.3892/ijo.2017.4181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743338PMC
January 2018

Mint3 in bone marrow-derived cells promotes lung metastasis in breast cancer model mice.

Biochem Biophys Res Commun 2017 08 19;490(3):688-692. Epub 2017 Jun 19.

Division of Cancer Cell Research, Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, 108-8639 Tokyo, Japan; Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, 108-8639 Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.06.102DOI Listing
August 2017

A One-Pot Three-Component Double-Click Method for Synthesis of [Cu]-Labeled Biomolecular Radiotherapeutics.

Sci Rep 2017 05 15;7(1):1912. Epub 2017 May 15.

Biofunctional Synthetic Chemistry Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.

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http://dx.doi.org/10.1038/s41598-017-02123-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432496PMC
May 2017

Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes.

Proc Natl Acad Sci U S A 2017 05 15;114(22):E4416-E4424. Epub 2017 May 15.

Division of Cancer Cell Research, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan;

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http://dx.doi.org/10.1073/pnas.1703171114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465932PMC
May 2017

Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation.

Sci Rep 2017 04 10;7:46174. Epub 2017 Apr 10.

Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.

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http://dx.doi.org/10.1038/srep46174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385562PMC
April 2017

Overview of BioBank Japan follow-up data in 32 diseases.

J Epidemiol 2017 Mar 10;27(3S):S22-S28. Epub 2017 Feb 10.

Laboratory of Molecular Medicine, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Laboratory of Clinical Genome Sequencing, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.je.2016.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363789PMC
March 2017

Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases.

J Epidemiol 2017 Mar 9;27(3S):S9-S21. Epub 2017 Feb 9.

Laboratory of Molecular Medicine, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Laboratory of Clinical Genome Sequencing, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.je.2016.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363792PMC
March 2017

Mint3/Apba3 depletion ameliorates severe murine influenza pneumonia and macrophage cytokine production in response to the influenza virus.

Sci Rep 2016 11 24;6:37815. Epub 2016 Nov 24.

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.

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http://dx.doi.org/10.1038/srep37815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121658PMC
November 2016

Cell division cycle associated 1 as a novel prognostic biomarker and therapeutic target for oral cancer.

Int J Oncol 2016 Oct 5;49(4):1385-93. Epub 2016 Aug 5.

Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.3892/ijo.2016.3649DOI Listing
October 2016

The ERK signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux.

Cell Discov 2016 26;2:16019. Epub 2016 Jul 26.

Division of Cancer Cell Research, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/celldisc.2016.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960523PMC
July 2016

NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells.

Sci Rep 2016 Mar 7;6:22784. Epub 2016 Mar 7.

Division of Cancer Cell Research, Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.

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http://dx.doi.org/10.1038/srep22784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780031PMC
March 2016

Xanthohumol inhibits STAT3 activation pathway leading to growth suppression and apoptosis induction in human cholangiocarcinoma cells.

Oncol Rep 2016 Apr 21;35(4):2065-72. Epub 2016 Jan 21.

Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.

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http://dx.doi.org/10.3892/or.2016.4584DOI Listing
April 2016

CRTAM determines the CD4+ cytotoxic T lymphocyte lineage.

J Exp Med 2016 Jan 22;213(1):123-38. Epub 2015 Dec 22.

Laboratory for Cell Signaling, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan

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http://www.jem.org/lookup/doi/10.1084/jem.20150519
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http://dx.doi.org/10.1084/jem.20150519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710199PMC
January 2016

Influence of Microbubbles on Free Radical Generation by Ultrasound in Aqueous Solution: Dependence of Ultrasound Frequency.

J Phys Chem B 2015 Oct 28;119(40):12887-93. Epub 2015 Sep 28.

Department of Materials Engineering, Nagaoka National College of Technology , Nishi-Katakai, Nagaoka, 940-2188, Japan.

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http://dx.doi.org/10.1021/acs.jpcb.5b05707DOI Listing
October 2015

A measles virus selectively blind to signaling lymphocytic activation molecule shows anti-tumor activity against lung cancer cells.

Oncotarget 2015 Sep;6(28):24895-903

Laboratory Animal Research Center, The Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://www.oncotarget.com/fulltext/4366
Publisher Site
http://dx.doi.org/10.18632/oncotarget.4366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694801PMC
September 2015

Dynamic regulation of a cell adhesion protein complex including CADM1 by combinatorial analysis of FRAP with exponential curve-fitting.

PLoS One 2015 17;10(3):e0116637. Epub 2015 Mar 17.

Division of Molecular Pathology, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan; Japan Science and Technology Agency, CREST, 4-5-3, Yonbancho, Chiyoda-ku, Tokyo, 102-8666, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116637PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364555PMC
February 2016

Immunohistochemical analysis of the expression of E-cadherin and ZEB1 in non-small cell lung cancer.

Pathol Int 2014 Nov 27;64(11):560-8. Epub 2014 Oct 27.

Molecular Pathology Laboratory, Institute of Medical Science, University of Tokyo, Tokyo, Japan; Department of Integrative Pathology, Jichi Medical University, Tochigi, Japan.

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http://dx.doi.org/10.1111/pin.12214DOI Listing
November 2014

STATs profiling reveals predominantly-activated STAT3 in cholangiocarcinoma genesis and progression.

J Hepatobiliary Pancreat Sci 2014 Oct 16;21(10):767-76. Epub 2014 Jul 16.

Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand; Liver Fluke and Cholangiocarcinoma Research Center, Khon Kaen University, Khon Kaen, Thailand.

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http://dx.doi.org/10.1002/jhbp.131DOI Listing
October 2014

Highlights of topic "Biochemical and molecular pathological aspects of cholangiocarcinoma".

J Hepatobiliary Pancreat Sci 2014 Jun;21(6):359-61

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1002/jhbp.91DOI Listing
June 2014

Expression of PRMT5 in lung adenocarcinoma and its significance in epithelial-mesenchymal transition.

Hum Pathol 2014 Jul 28;45(7):1397-405. Epub 2014 Feb 28.

Molecular Pathology Laboratory, Institute of Medical Science, the University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.humpath.2014.02.013DOI Listing
July 2014

Highlights of topic "Etiology and epidemiology of cholangiocarcinoma".

J Hepatobiliary Pancreat Sci 2014 May;21(5):299-300

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1002/jhbp.90DOI Listing
May 2014

Preface to topic "International collaboration to control cholangiocarcinoma".

J Hepatobiliary Pancreat Sci 2014 May;21(5):297-8

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1002/jhbp.89DOI Listing
May 2014

CRTAM controls residency of gut CD4+CD8+ T cells in the steady state and maintenance of gut CD4+ Th17 during parasitic infection.

J Exp Med 2014 Apr 31;211(4):623-33. Epub 2014 Mar 31.

Department of Pathology and Immunology, 2 Department of Internal Medicine, 3 Department of Molecular Microbiology, and 4 Howard Hughes Medical Institute, Washington University School of Medicine, St. Louis, MO 63110.

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http://www.jem.org/lookup/doi/10.1084/jem.20130904
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http://dx.doi.org/10.1084/jem.20130904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978276PMC
April 2014

Genomic and transcriptional alterations of cholangiocarcinoma.

J Hepatobiliary Pancreat Sci 2014 Jun 13;21(6):380-7. Epub 2014 Feb 13.

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1002/jhbp.67DOI Listing
June 2014

Trans-homophilic interaction of CADM1 activates PI3K by forming a complex with MAGuK-family proteins MPP3 and Dlg.

PLoS One 2014 4;9(2):e82894. Epub 2014 Feb 4.

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082894PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913574PMC
December 2014

Increased ectodomain shedding of lung epithelial cell adhesion molecule 1 as a cause of increased alveolar cell apoptosis in emphysema.

Thorax 2014 Mar 2;69(3):223-31. Epub 2013 Oct 2.

Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Graduate School of Biomedical Sciences, Hiroshima University, , Hiroshima, Japan.

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http://dx.doi.org/10.1136/thoraxjnl-2013-203867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933066PMC
March 2014

[Pharmacological and clinical profile of golimumab (Simponi®)].

Nihon Yakurigaku Zasshi 2013 May;141(5):275-85

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http://dx.doi.org/10.1254/fpj.141.275DOI Listing
May 2013

Identification of CCDC6-RET fusion in the human lung adenocarcinoma cell line, LC-2/ad.

J Thorac Oncol 2012 Dec;7(12):1872-1876

Department of Pathology, Division of Integrative Pathology, Jichi Medical University, Shimotsuke, Tochigi, Japan. Electronic address:

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http://dx.doi.org/10.1097/JTO.0b013e3182721ed1DOI Listing
December 2012

Cell adhesion molecule 1 is a new osteoblastic cell adhesion molecule and a diagnostic marker for osteosarcoma.

Life Sci 2013 Jan 7;92(1):91-9. Epub 2012 Nov 7.

Department of Pathology, Faculty of Medicine, Kinki University, Osaka 589-8511, Japan.

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http://dx.doi.org/10.1016/j.lfs.2012.10.021DOI Listing
January 2013

Adhesion molecule CADM1 contributes to gap junctional communication among pancreatic islet α-cells and prevents their excessive secretion of glucagon.

Islets 2012 Jan-Feb;4(1):49-55. Epub 2012 Jan 1.

Division of Molecular Pathology; Institute of Medical Science; University of Tokyo; Tokyo, Japan.

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http://dx.doi.org/10.4161/isl.18675DOI Listing
January 2015

Compensatory upregulation of myelin protein zero-like 2 expression in spermatogenic cells in cell adhesion molecule-1-deficient mice.

Acta Histochem Cytochem 2012 Feb 24;45(1):47-56. Epub 2012 Jan 24.

Department of Histology and Embryology, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, Japan.

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http://dx.doi.org/10.1267/ahc.11057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317495PMC
February 2012

Expression of a splicing variant of the CADM1 specific to small cell lung cancer.

Cancer Sci 2012 Jun 15;103(6):1051-7. Epub 2012 May 15.

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2012.02277.xDOI Listing
June 2012

Upregulation of notch2 and six1 is associated with progression of early-stage lung adenocarcinoma and a more aggressive phenotype at advanced stages.

Clin Cancer Res 2012 Feb 21;18(4):945-55. Epub 2011 Dec 21.

Surgical Oncology, Division of Genome Radiobiology and Medicine, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1946DOI Listing
February 2012

Transcriptional regulation of the CADM1 gene by retinoic acid during the neural differentiation of murine embryonal carcinoma P19 cells.

Genes Cells 2011 Jul 15;16(7):791-802. Epub 2011 Jun 15.

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2011.01525.xDOI Listing
July 2011

Aberrations of a cell adhesion molecule CADM4 in renal clear cell carcinoma.

Int J Cancer 2012 Mar 21;130(6):1329-37. Epub 2011 Jul 21.

Division of Molecular Pathology, Institute of Medical Science, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1002/ijc.26160DOI Listing
March 2012

Aberrant expression of tumor suppressors CADM1 and 4.1B in invasive lesions of primary breast cancer.

Breast Cancer 2012 Jul 28;19(3):242-52. Epub 2011 Apr 28.

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, 108-8639, Tokyo, Japan.

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http://dx.doi.org/10.1007/s12282-011-0272-7DOI Listing
July 2012

Enhanced nerve-mast cell interaction by a neuronal short isoform of cell adhesion molecule-1.

J Immunol 2011 May 11;186(10):5983-92. Epub 2011 Apr 11.

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.4049/jimmunol.1002244DOI Listing
May 2011

Steroid receptor expression in thymomas and thymic carcinomas.

Cancer 2011 Oct 22;117(19):4396-405. Epub 2011 Mar 22.

Pathology and Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1002/cncr.26061DOI Listing
October 2011

Noncontact estimation of intercellular breaking force using a femtosecond laser impulse quantified by atomic force microscopy.

Proc Natl Acad Sci U S A 2011 Feb 18;108(5):1777-82. Epub 2011 Jan 18.

Graduate School of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara, Japan.

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http://dx.doi.org/10.1073/pnas.1006847108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033285PMC
February 2011

[Genomic analysis of hepatocellular carcinoma and its application to diagnosis].

Nihon Rinsho 2010 Aug;68 Suppl 8:458-61

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo.

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August 2010

[Neurophysiological effect of flavor and caffeine added to toothpaste].

Sangyo Eiseigaku Zasshi 2010 28;52(4):172-81. Epub 2010 Apr 28.

Tokyo Laboratory, Kao Corporation, Tokyo 131-8501, Japan.

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http://dx.doi.org/10.1539/sangyoeisei.b10002DOI Listing
December 2010

Application of tooth brushing behavior to active rest.

Sangyo Eiseigaku Zasshi 2010 17;52(2):67. Epub 2010 Feb 17.

Tokyo Laboratory, Kao Corporation, Japan.

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http://dx.doi.org/10.1539/sangyoeisei.b9009DOI Listing
July 2010

Tumor suppressor CADM1 is involved in epithelial cell structure.

Biochem Biophys Res Commun 2009 Dec 23;390(3):977-82. Epub 2009 Oct 23.

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2009.10.088DOI Listing
December 2009

Density functional study of the high-temperature oxidation of o-, m- and p-xylyl radicals.

J Phys Chem A 2009 Oct;113(40):10652-66

Department of Materials Engineering, Nagaoka National College of Technology, Nishikatagai, Nagaoka, 940-8532 Japan.

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http://dx.doi.org/10.1021/jp902204aDOI Listing
October 2009

[Advances in genome analysis of solid tumors].

Nihon Rinsho 2009 Jun;67(6):1115-9

Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo.

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June 2009

Expression of a soluble isoform of cell adhesion molecule 1 in the brain and its involvement in directional neurite outgrowth.

Am J Pathol 2009 Jun 12;174(6):2278-89. Epub 2009 May 12.

Division of Molecular Pathology, Department of Cancer Biology, Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S000294401061086
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http://dx.doi.org/10.2353/ajpath.2009.080743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684192PMC
June 2009

Identification of SMURF1 as a possible target for 7q21.3-22.1 amplification detected in a pancreatic cancer cell line by in-house array-based comparative genomic hybridization.

Cancer Sci 2008 May;99(5):986-94

Department of Molecular Cytogenetics, Medical Research Institute and School of Biomedical Science, Tokyo Medical and Dental University, 1-5-45 Yushima Bunkyo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2008.00779.xDOI Listing
May 2008