Yoshinori Iwatani

Yoshinori Iwatani

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Yoshinori Iwatani

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Association of IFNG gene methylation in peripheral blood cells with the development and prognosis of autoimmune thyroid diseases.

Cytokine 2019 Nov 3;123:154770. Epub 2019 Jul 3.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Yamadaoka 1-7, Suita, Osaka 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2019.154770DOI Listing
November 2019

Increases of CD80 and CD86 Expression on Peripheral Blood Cells and their Gene Polymorphisms in Autoimmune Thyroid Disease.

Immunol Invest 2019 Nov 22:1-13. Epub 2019 Nov 22.

Department of Biomedical Informatics Division of Health Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1080/08820139.2019.1688343DOI Listing
November 2019

Association of Polymorphisms and its Protein Expression with the Development and Prognosis of Autoimmune Thyroid Diseases.

Immunol Invest 2019 Sep 11:1-14. Epub 2019 Sep 11.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka , Japan.

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http://dx.doi.org/10.1080/08820139.2019.1659811DOI Listing
September 2019

Association of gene methylation in peripheral blood cells with the development and prognosis of autoimmune thyroid diseases.

Autoimmunity 2019 Nov - Dec;52(7-8):251-255. Epub 2019 Sep 25.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Suita, Japan.

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http://dx.doi.org/10.1080/08916934.2019.1669568DOI Listing
September 2019

Autoantibodies detected in patients with vitiligo vulgaris but not in those with rhododendrol-induced leukoderma.

J Dermatol Sci 2019 08 2;95(2):80-83. Epub 2019 Jul 2.

Department of Dermatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 Japan; Department of Pigmentation Research and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, 545-8585 Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2019.06.009DOI Listing
August 2019

Polymorphisms in Th17-related genes and the pathogenesis of autoimmune thyroid disease.

Autoimmunity 2018 Nov 24:1-10. Epub 2018 Nov 24.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Osaka , Japan.

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https://www.tandfonline.com/doi/full/10.1080/08916934.2018.1
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http://dx.doi.org/10.1080/08916934.2018.1534963DOI Listing
November 2018

Association of the polymorphisms in Th2 chemotaxis-related genes with the development and prognosis of autoimmune thyroid diseases.

Endocr J 2018 Aug 30;65(8):815-826. Epub 2018 May 30.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

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https://www.jstage.jst.go.jp/article/endocrj/65/8/65_EJ18-00
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http://dx.doi.org/10.1507/endocrj.EJ18-0050DOI Listing
August 2018

Functional Polymorphisms of the Type 1 and Type 2 Iodothyronine Deiodinase Genes in Autoimmune Thyroid Diseases.

Immunol Invest 2018 Jul 12;47(5):534-542. Epub 2018 Apr 12.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Osaka , Japan.

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http://dx.doi.org/10.1080/08820139.2018.1458861DOI Listing
July 2018

Methylation levels of the TNFA gene are different between Graves' and Hashimoto's diseases and influenced by the TNFA polymorphism.

Autoimmunity 2018 05 11;51(3):118-125. Epub 2018 Mar 11.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.

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http://dx.doi.org/10.1080/08916934.2018.1448078DOI Listing
May 2018

Mean platelet component and mean platelet volume as useful screening markers for myelodysplastic syndrome.

Health Sci Rep 2018 May 2;1(5):e50. Epub 2018 May 2.

Department of Central Clinical Laboratory Osaka Medical College Hospital Takatsuki Osaka Japan.

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http://dx.doi.org/10.1002/hsr2.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266360PMC
May 2018

Polymorphisms and expression of genes encoding Argonautes 1 and 2 in autoimmune thyroid diseases.

Autoimmunity 2018 02 19;51(1):35-42. Epub 2017 Dec 19.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.

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http://dx.doi.org/10.1080/08916934.2017.1416468DOI Listing
February 2018

Genotype-based epigenetic differences in monozygotic twins discordant for positive anti-thyroglobulin autoantibodies.

Thyroid 2017 11 4. Epub 2017 Nov 4.

Osaka University Graduate School of Medicine, Division of Health Sciences, Department of Biomedical Informatics, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/thy.2017.0273DOI Listing
November 2017

The polymorphisms in the thyroid peroxidase gene were associated with the development of autoimmune thyroid disease and the serum levels of anti-thyroid peroxidase antibody.

Endocr J 2017 Oct 25;64(10):1025-1032. Epub 2017 Aug 25.

Department of Biomedical Informatics Division of Health Sciences Osaka University Graduate School of Medicine, Suita 565-0871, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ17-0191DOI Listing
October 2017

Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts.

Authors:
Karri Silventoinen Aline Jelenkovic Antti Latvala Reijo Sund Yoshie Yokoyama Vilhelmina Ullemar Catarina Almqvist Catherine A Derom Robert F Vlietinck Ruth J F Loos Christian Kandler Chika Honda Fujio Inui Yoshinori Iwatani Mikio Watanabe Esther Rebato Maria A Stazi Corrado Fagnani Sonia Brescianini Yoon-Mi Hur Hoe-Uk Jeong Tessa L Cutler John L Hopper Andreas Busjahn Kimberly J Saudino Fuling Ji Feng Ning Zengchang Pang Richard J Rose Markku Koskenvuo Kauko Heikkilä Wendy Cozen Amie E Hwang Thomas M Mack Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Fruhling Rijsdijk Joohon Sung Jina Kim Jooyeon Lee Sooji Lee Tracy L Nelson Keith E Whitfield Qihua Tan Dongfeng Zhang Clare H Llewellyn Abigail Fisher S Alexandra Burt Kelly L Klump Ariel Knafo-Noam David Mankuta Lior Abramson Sarah E Medland Nicholas G Martin Grant W Montgomery Patrik K E Magnusson Nancy L Pedersen Anna K Dahl Aslan Robin P Corley Brooke M Huibregtse Sevgi Y Öncel Fazil Aliev Robert F Krueger Matt McGue Shandell Pahlen Gonneke Willemsen Meike Bartels Catharina E M van Beijsterveldt Judy L Silberg Lindon J Eaves Hermine H Maes Jennifer R Harris Ingunn Brandt Thomas S Nilsen Finn Rasmussen Per Tynelius Laura A Baker Catherine Tuvblad Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde Margaret Gatz David A Butler Paul Lichtenstein Jack H Goldberg K Paige Harden Elliot M Tucker-Drob Glen E Duncan Dedra Buchwald Adam D Tarnoki David L Tarnoki Carol E Franz William S Kremen Michael J Lyons José A Maia Duarte L Freitas Eric Turkheimer Thorkild I A Sørensen Dorret I Boomsma Jaakko Kaprio

Twin Res Hum Genet 2017 10;20(5):395-405

Institute for Molecular Medicine FIMM,Helsinki,Finland.

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http://dx.doi.org/10.1017/thg.2017.49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969906PMC
October 2017

Association of the polymorphisms in the gene encoding thyroglobulin with the development and prognosis of autoimmune thyroid disease.

Autoimmunity 2017 Sep 4;50(6):386-392. Epub 2017 Jul 4.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Osaka , Japan.

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http://dx.doi.org/10.1080/08916934.2017.1344971DOI Listing
September 2017

Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts.

Authors:
Karri Silventoinen Aline Jelenkovic Reijo Sund Yoshie Yokoyama Yoon-Mi Hur Wendy Cozen Amie E Hwang Thomas M Mack Chika Honda Fujio Inui Yoshinori Iwatani Mikio Watanabe Rie Tomizawa Kirsi H Pietiläinen Aila Rissanen Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Fruhling Rijsdijk Qihua Tan Dongfeng Zhang Zengchang Pang Maarit Piirtola Sari Aaltonen Sevgi Y Öncel Fazil Aliev Esther Rebato Jacob B Hjelmborg Kaare Christensen Axel Skytthe Kirsten O Kyvik Judy L Silberg Lindon J Eaves Tessa L Cutler Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde Yun-Mi Song Sarah Yang Kayoung Lee Carol E Franz William S Kremen Michael J Lyons Andreas Busjahn Tracy L Nelson Keith E Whitfield Christian Kandler Kerry L Jang Margaret Gatz David A Butler Maria A Stazi Corrado Fagnani Cristina D'Ippolito Glen E Duncan Dedra Buchwald Nicholas G Martin Sarah E Medland Grant W Montgomery Hoe-Uk Jeong Gary E Swan Ruth Krasnow Patrik Ke Magnusson Nancy L Pedersen Anna K Dahl Aslan Tom A McAdams Thalia C Eley Alice M Gregory Per Tynelius Laura A Baker Catherine Tuvblad Gombojav Bayasgalan Danshiitsoodol Narandalai Timothy D Spector Massimo Mangino Genevieve Lachance S Alexandra Burt Kelly L Klump Jennifer R Harris Ingunn Brandt Thomas S Nilsen Robert F Krueger Matt McGue Shandell Pahlen Robin P Corley Brooke M Huibregtse Meike Bartels Catharina Em van Beijsterveldt Gonneke Willemsen Jack H Goldberg Finn Rasmussen Adam D Tarnoki David L Tarnoki Catherine A Derom Robert F Vlietinck Ruth Jf Loos John L Hopper Joohon Sung Hermine H Maes Eric Turkheimer Dorret I Boomsma Thorkild Ia Sørensen Jaakko Kaprio

Am J Clin Nutr 2017 Aug 5;106(2):457-466. Epub 2017 Jul 5.

Public Health, and.

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http://dx.doi.org/10.3945/ajcn.117.153643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525120PMC
August 2017

Association of IL-10-Regulating MicroRNAs in Peripheral Blood Mononuclear Cells with the Pathogenesis of Autoimmune Thyroid Disease.

Immunol Invest 2017 Aug 25;46(6):590-602. Epub 2017 Jul 25.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.

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http://dx.doi.org/10.1080/08820139.2017.1322975DOI Listing
August 2017

Functional polymorphisms affecting Th1 differentiation are associated with the severity of autoimmune thyroid diseases.

Endocr J 2017 Jul 16;64(7):695-703. Epub 2017 May 16.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ16-0551DOI Listing
July 2017

Polymorphisms and expression of toll-like receptors in autoimmune thyroid diseases.

Autoimmunity 2017 May 26;50(3):182-191. Epub 2016 Dec 26.

a Department of Biomedical Informatics , Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka , Japan and.

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http://dx.doi.org/10.1080/08916934.2016.1261835DOI Listing
May 2017

Intraindividual variation of microRNA expression levels in plasma and peripheral blood mononuclear cells and the associations of these levels with the pathogenesis of autoimmune thyroid diseases.

Clin Chem Lab Med 2017 May;55(5):626-635

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Yamadaoka 1-7 Suita, Osaka 565-0871.

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http://dx.doi.org/10.1515/cclm-2016-0449DOI Listing
May 2017

TSHR Gene Polymorphisms in the Enhancer Regions Are Most Strongly Associated with the Development of Graves' Disease, Especially Intractable Disease, and of Hashimoto's Disease.

Thyroid 2017 01 18;27(1):111-119. Epub 2016 Nov 18.

1 Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka, Japan .

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http://dx.doi.org/10.1089/thy.2016.0345DOI Listing
January 2017

DICER and DROSHA gene expression and polymorphisms in autoimmune thyroid diseases.

Autoimmunity 2016 12 3;49(8):514-522. Epub 2016 Nov 3.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Osaka , Japan and.

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http://dx.doi.org/10.1080/08916934.2016.1230846DOI Listing
December 2016

Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994.

Authors:
Aline Jelenkovic Yoon-Mi Hur Reijo Sund Yoshie Yokoyama Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Fruhling Rijsdijk Qihua Tan Dongfeng Zhang Zengchang Pang Sari Aaltonen Kauko Heikkilä Sevgi Y Öncel Fazil Aliev Esther Rebato Adam D Tarnoki David L Tarnoki Kaare Christensen Axel Skytthe Kirsten O Kyvik Judy L Silberg Lindon J Eaves Hermine H Maes Tessa L Cutler John L Hopper Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde Wendy Cozen Amie E Hwang Thomas M Mack Joohon Sung Yun-Mi Song Sarah Yang Kayoung Lee Carol E Franz William S Kremen Michael J Lyons Andreas Busjahn Tracy L Nelson Keith E Whitfield Christian Kandler Kerry L Jang Margaret Gatz David A Butler Maria A Stazi Corrado Fagnani Cristina D'Ippolito Glen E Duncan Dedra Buchwald Catherine A Derom Robert F Vlietinck Ruth Jf Loos Nicholas G Martin Sarah E Medland Grant W Montgomery Hoe-Uk Jeong Gary E Swan Ruth Krasnow Patrik Ke Magnusson Nancy L Pedersen Anna K Dahl-Aslan Tom A McAdams Thalia C Eley Alice M Gregory Per Tynelius Laura A Baker Catherine Tuvblad Gombojav Bayasgalan Danshiitsoodol Narandalai Paul Lichtenstein Timothy D Spector Massimo Mangino Genevieve Lachance Meike Bartels Toos Cem van Beijsterveldt Gonneke Willemsen S Alexandra Burt Kelly L Klump Jennifer R Harris Ingunn Brandt Thomas Sevenius Nilsen Robert F Krueger Matt McGue Shandell Pahlen Robin P Corley Jacob V B Hjelmborg Jack H Goldberg Yoshinori Iwatani Mikio Watanabe Chika Honda Fujio Inui Finn Rasmussen Brooke M Huibregtse Dorret I Boomsma Thorkild I A Sørensen Jaakko Kaprio Karri Silventoinen

Elife 2016 12 14;5. Epub 2016 Dec 14.

Department of Social Research, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.7554/eLife.20320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156525PMC
December 2016

Optimization of Recovery and Analysis of RNA in Sorted Cells in mRNA Quantification After Fluorescence-activated Cell Sorting.

Ann Clin Lab Sci 2016 Dec;46(6):571-577

Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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December 2016

Association of polymorphisms in the ICOS and ICOSL genes with the pathogenesis of autoimmune thyroid diseases.

Endocr J 2016 12;63(1):61-8. Epub 2015 Nov 12.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ15-0435DOI Listing
November 2016

Involvement of genes encoding apoptosis regulatory factors (FAS, FASL, TRAIL, BCL2, TNFR1 and TNFR2) in the pathogenesis of autoimmune thyroid diseases.

Hum Immunol 2016 Oct 22;77(10):944-951. Epub 2016 Jul 22.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University, Graduate School of Medicine, 1-7 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.humimm.2016.07.232DOI Listing
October 2016

Association between functional SIRT1 polymorphisms and the clinical characteristics of patients with autoimmune thyroid disease.

Autoimmunity 2016 08 31;49(5):329-37. Epub 2016 May 31.

a Department of Biomedical Informatics , Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka , Japan and.

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http://dx.doi.org/10.3109/08916934.2015.1134506DOI Listing
August 2016

Association of the polymorphisms of chemokine genes (IL8, RANTES, MIG, IP10, MCP1 and IL16) with the pathogenesis of autoimmune thyroid diseases.

Autoimmunity 2016 08 31;49(5):312-9. Epub 2016 May 31.

a Department of Biomedical Informatics , Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka , Japan and.

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http://dx.doi.org/10.3109/08916934.2015.1134507DOI Listing
August 2016

Increases of microRNA let-7e in peripheral blood mononuclear cells in Hashimoto's disease.

Endocr J 2016 Apr 28;63(4):375-80. Epub 2016 Jan 28.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ15-0577DOI Listing
April 2016

Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project.

Authors:
Aline Jelenkovic Yoshie Yokoyama Reijo Sund Chika Honda Leonie H Bogl Sari Aaltonen Fuling Ji Feng Ning Zengchang Pang Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde S Alexandra Burt Kelly L Klump Sarah E Medland Grant W Montgomery Christian Kandler Tom A McAdams Thalia C Eley Alice M Gregory Kimberly J Saudino Lise Dubois Michel Boivin Adam D Tarnoki David L Tarnoki Claire M A Haworth Robert Plomin Sevgi Y Öncel Fazil Aliev Maria A Stazi Corrado Fagnani Cristina D'Ippolito Jeffrey M Craig Richard Saffery Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Fruhling Rijsdijk Timothy Spector Massimo Mangino Genevieve Lachance Margaret Gatz David A Butler Gombojav Bayasgalan Danshiitsoodol Narandalai Duarte L Freitas José Antonio Maia K Paige Harden Elliot M Tucker-Drob Bia Kim Youngsook Chong Changhee Hong Hyun Jung Shin Kaare Christensen Axel Skytthe Kirsten O Kyvik Catherine A Derom Robert F Vlietinck Ruth J F Loos Wendy Cozen Amie E Hwang Thomas M Mack Mingguang He Xiaohu Ding Billy Chang Judy L Silberg Lindon J Eaves Hermine H Maes Tessa L Cutler John L Hopper Kelly Aujard Patrik K E Magnusson Nancy L Pedersen Anna K Dahl Aslan Yun-Mi Song Sarah Yang Kayoung Lee Laura A Baker Catherine Tuvblad Morten Bjerregaard-Andersen Henning Beck-Nielsen Morten Sodemann Kauko Heikkilä Qihua Tan Dongfeng Zhang Gary E Swan Ruth Krasnow Kerry L Jang Ariel Knafo-Noam David Mankuta Lior Abramson Paul Lichtenstein Robert F Krueger Matt McGue Shandell Pahlen Per Tynelius Glen E Duncan Dedra Buchwald Robin P Corley Brooke M Huibregtse Tracy L Nelson Keith E Whitfield Carol E Franz William S Kremen Michael J Lyons Syuichi Ooki Ingunn Brandt Thomas Sevenius Nilsen Fujio Inui Mikio Watanabe Meike Bartels Toos C E M van Beijsterveldt Jane Wardle Clare H Llewellyn Abigail Fisher Esther Rebato Nicholas G Martin Yoshinori Iwatani Kazuo Hayakawa Joohon Sung Jennifer R Harris Gonneke Willemsen Andreas Busjahn Jack H Goldberg Finn Rasmussen Yoon-Mi Hur Dorret I Boomsma Thorkild I A Sørensen Jaakko Kaprio Karri Silventoinen

Twin Res Hum Genet 2015 Oct 4;18(5):557-70. Epub 2015 Sep 4.

Department of Social Research,University of Helsinki,Helsinki,Finland.

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http://dx.doi.org/10.1017/thg.2015.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605819PMC
October 2015

The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits.

Authors:
Karri Silventoinen Aline Jelenkovic Reijo Sund Chika Honda Sari Aaltonen Yoshie Yokoyama Adam D Tarnoki David L Tarnoki Feng Ning Fuling Ji Zengchang Pang Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde S Alexandra Burt Kelly L Klump Sarah E Medland Grant W Montgomery Christian Kandler Tom A McAdams Thalia C Eley Alice M Gregory Kimberly J Saudino Lise Dubois Michel Boivin Claire M A Haworth Robert Plomin Sevgi Y Öncel Fazil Aliev Maria A Stazi Corrado Fagnani Cristina D'Ippolito Jeffrey M Craig Richard Saffery Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Timothy Spector Massimo Mangino Genevieve Lachance Margaret Gatz David A Butler Gombojav Bayasgalan Danshiitsoodol Narandalai Duarte L Freitas José Antonio Maia K Paige Harden Elliot M Tucker-Drob Kaare Christensen Axel Skytthe Kirsten O Kyvik Changhee Hong Youngsook Chong Catherine A Derom Robert F Vlietinck Ruth J F Loos Wendy Cozen Amie E Hwang Thomas M Mack Mingguang He Xiaohu Ding Billy Chang Judy L Silberg Lindon J Eaves Hermine H Maes Tessa L Cutler John L Hopper Kelly Aujard Patrik K E Magnusson Nancy L Pedersen Anna K Dahl Aslan Yun-Mi Song Sarah Yang Kayoung Lee Laura A Baker Catherine Tuvblad Morten Bjerregaard-Andersen Henning Beck-Nielsen Morten Sodemann Kauko Heikkilä Qihua Tan Dongfeng Zhang Gary E Swan Ruth Krasnow Kerry L Jang Ariel Knafo-Noam David Mankuta Lior Abramson Paul Lichtenstein Robert F Krueger Matt McGue Shandell Pahlen Per Tynelius Glen E Duncan Dedra Buchwald Robin P Corley Brooke M Huibregtse Tracy L Nelson Keith E Whitfield Carol E Franz William S Kremen Michael J Lyons Syuichi Ooki Ingunn Brandt Thomas Sevenius Nilsen Fujio Inui Mikio Watanabe Meike Bartels Toos C E M van Beijsterveldt Jane Wardle Clare H Llewellyn Abigail Fisher Esther Rebato Nicholas G Martin Yoshinori Iwatani Kazuo Hayakawa Finn Rasmussen Joohon Sung Jennifer R Harris Gonneke Willemsen Andreas Busjahn Jack H Goldberg Dorret I Boomsma Yoon-Mi Hur Thorkild I A Sørensen Jaakko Kaprio

Twin Res Hum Genet 2015 Aug 27;18(4):348-60. Epub 2015 May 27.

Department of Public Health,University of Helsinki,Helsinki,Finland.

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http://www.journals.cambridge.org/abstract_S1832427415000298
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http://dx.doi.org/10.1017/thg.2015.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696543PMC
August 2015

The relationship between skewed X chromosome inactivation and the prognosis of Graves' and Hashimoto's diseases.

Thyroid 2015 Feb 10;25(2):256-61. Epub 2014 Dec 10.

1 Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka, Japan .

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http://dx.doi.org/10.1089/thy.2014.0318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322037PMC
February 2015

Clinical usefulness of the PAXgene™ bone marrow RNA system for stabilizing total RNA.

J Clin Lab Anal 2015 Jan 28;29(1):61-7. Epub 2014 Mar 28.

Department of Clinical Laboratory Science, Faculty of Health Care, Tenri Health Care University, Tenri, Japan; Department of Biomedical Informatics, Division of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.

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http://dx.doi.org/10.1002/jcla.21729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807000PMC
January 2015

In vitro evaluations of topical agents to treat Acanthamoeba keratitis.

Ophthalmology 2014 Oct 29;121(10):2059-65. Epub 2014 May 29.

Department of Ophthalmology, Ehime University School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1016/j.ophtha.2014.04.013DOI Listing
October 2014

The GG genotype of the -1125G/T polymorphism in the EPO gene protects against the development of Graves' disease.

Immunol Lett 2013 Nov-Dec;156(1-2):156-8. Epub 2013 Oct 28.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Yamadaoka 1-7, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.imlet.2013.10.006DOI Listing
July 2014

An improved protocol for mRNA quantification after fluorescence-activated cell sorting with an increased signal to noise ratio in flow cytometry.

Mol Biotechnol 2014 Jul;56(7):591-8

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, D2, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

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http://dx.doi.org/10.1007/s12033-014-9733-5DOI Listing
July 2014

IL-10 -592A/C polymorphism is associated with severity of Hashimoto's disease.

Cytokine 2013 Oct 10;64(1):370-4. Epub 2013 Jun 10.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Yamadaoka 1-7, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.cyto.2013.05.014DOI Listing
October 2013

Ezetimibe increases hepatic iron levels in mice fed a high-fat diet.

J Pharmacol Exp Ther 2013 Jun 28;345(3):483-91. Epub 2013 Mar 28.

Department of Clinical Laboratory Medicine, Kinki University Faculty of Medicine, 377-2, Ohnohigashi, Osakasayama 589-8511, Japan.

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http://dx.doi.org/10.1124/jpet.113.203448DOI Listing
June 2013

Preparation of thyroid follicular cells for mRNA quantification after fluorescence-activated cell sorting.

Scand J Clin Lab Invest 2013 Apr 2;73(3):245-52. Epub 2013 Apr 2.

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.3109/00365513.2013.769624DOI Listing
April 2013

Genes that characterize T3-predominant Graves' thyroid tissues.

Eur J Endocrinol 2013 Feb 17;168(2):137-44. Epub 2013 Jan 17.

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, D2, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1530/EJE-12-0507DOI Listing
February 2013

Interference by pralidoxime (PAM) salts in clinical laboratory tests.

Clin Chim Acta 2013 Feb 27;416:72-9. Epub 2012 Nov 27.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00098981120055
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http://dx.doi.org/10.1016/j.cca.2012.11.017DOI Listing
February 2013

An overview of multidisciplinary research resources at the Osaka University Center for Twin Research.

Twin Res Hum Genet 2013 Feb 8;16(1):217-20. Epub 2013 Jan 8.

Center for Twin Research, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1017/thg.2012.141DOI Listing
February 2013

Measurement of TFF3 mRNA in aspirates from thyroid nodules using mesh filtration: the first clinical trial in 130 cases.

Endocr J 2012 26;59(7):621-30. Epub 2012 May 26.

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.

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http://dx.doi.org/10.1507/endocrj.ej12-0077DOI Listing
January 2013

Associations between autoimmune thyroid disease prognosis and functional polymorphisms of susceptibility genes, CTLA4, PTPN22, CD40, FCRL3, and ZFAT, previously revealed in genome-wide association studies.

J Clin Immunol 2012 Dec 17;32(6):1243-52. Epub 2012 Jun 17.

Department of Biomedical Informatics, Division of Health Sciences, Graduate School of Medicine, Osaka University, Yamadaoka 1-7, Suita, Osaka, Japan.

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http://dx.doi.org/10.1007/s10875-012-9721-0DOI Listing
December 2012

[FACS-mQ as a powerful clinical test in the cancer stem cell era].

Rinsho Byori 2012 Aug;60(8):748-52

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.

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August 2012

Functional polymorphisms in TBX21 and HLX are associated with development and prognosis of Graves' disease.

Autoimmunity 2012 Mar 21;45(2):129-36. Epub 2011 Oct 21.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.3109/08916934.2011.622013DOI Listing
March 2012

A solution for distinguishing Le(a-b-) sera in CA19-9 assays using SphereLight 180 and Architect i2000 assays.

Clin Chim Acta 2012 Jan 14;413(1-2):278-81. Epub 2011 Sep 14.

Division of Laboratory for Clinical Investigation, Department of Medical Technology, Osaka University Hospital, Suita, Osaka, Japan.

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http://dx.doi.org/10.1016/j.cca.2011.09.009DOI Listing
January 2012

mRNA quantification after fluorescence activated cell sorting using locked nucleic acid probes.

Mol Biotechnol 2011 Sep;49(1):42-7

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, D2, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

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http://link.springer.com/10.1007/s12033-011-9375-9
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http://dx.doi.org/10.1007/s12033-011-9375-9DOI Listing
September 2011

Transcriptional activity of the 5'-flanking region of the thyroid transcription factor-1 gene in human thyroid cell lines.

Genet Mol Biol 2011 Jan 1;34(1):6-10. Epub 2011 Mar 1.

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1590/S1415-47572010005000109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085375PMC
January 2011

Messenger RNA quantification after fluorescence-activated cell sorting using in situ hybridization.

Cytometry A 2010 Nov;77(11):1032-7

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

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http://doi.wiley.com/10.1002/cyto.a.20973
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http://dx.doi.org/10.1002/cyto.a.20973DOI Listing
November 2010

Messenger RNA quantification after fluorescence activated cell sorting using intracellular antigens.

Biochem Biophys Res Commun 2010 Jul 27;397(3):425-8. Epub 2010 May 27.

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2010.05.112DOI Listing
July 2010

Increases in urinary creatinine and blood pressure during early pregnancy in pre-eclampsia.

Ann Clin Biochem 2010 Jul 28;47(Pt 4):336-42. Epub 2010 May 28.

Department of Biomedical Informatics, Division of Health Sciences, Graduate School of Medicine, Osaka University, Japan.

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http://dx.doi.org/10.1258/acb.2010.090290DOI Listing
July 2010

Postpartum increase of serum thioredoxin concentrations and the relation to CD8 lymphocytes.

Ann Clin Biochem 2010 Jan 25;47(Pt 1):62-6. Epub 2009 Nov 25.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1258/acb.2009.009120DOI Listing
January 2010

Expression of nestin mRNA is a differentiation marker in thyroid tumors.

Cancer Lett 2009 Jul 5;280(1):61-4. Epub 2009 Mar 5.

Department of Laboratory Medicine, Osaka University Medical School, 2-2 D2, Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.canlet.2009.02.006DOI Listing
July 2009

Acquired activated protein C resistance is associated with IgG antibodies to protein S in patients with systemic lupus erythematosus.

Thromb Res 2009 May 7;124(1):127-31. Epub 2009 Jan 7.

Department of Laboratory Science, Faculty of Health Science, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, Japan.

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http://www.clinchem.org/content/51/3/545.full.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S004938480800538
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http://dx.doi.org/10.1016/j.thromres.2008.11.006DOI Listing
May 2009

Increases of the Th1/Th2 cell ratio in severe Hashimoto's disease and in the proportion of Th17 cells in intractable Graves' disease.

Thyroid 2009 May;19(5):495-501

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Yamadaoka 1-7, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/thy.2008.0423DOI Listing
May 2009

In vitro antifungal combination effects of micafungin with fluconazole, voriconazole, amphotericin B, and flucytosine against clinical isolates of Candida species.

J Infect Chemother 2009 Feb 12;15(1):1-5. Epub 2009 Mar 12.

Laboratory for Clinical Investigation, Osaka University Hospital, 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1007/s10156-008-0653-9DOI Listing
February 2009

[Analysis of the causal relations between serum ferritin elevation and latent pathologic factors by structural equation modeling].

Rinsho Byori 2009 Jan;57(1):17-23

Division of Laboratory for Clinical Investigation, Department of Medical Technology, Osaka University Hospital, Suita 565-0871, Japan.

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January 2009

[The medical technologist as a key professional in medical care in the 21st century].

Rinsho Byori 2008 Oct;56(10):915-23

Department of Biomedical Informatics, Area of Medical Technology and Science, Division of Health Sciences, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.

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October 2008

Decrease of intrathyroidal CD161+Valpha24+Vbeta11+ NKT cells in Graves' disease.

Endocr J 2008 Mar 4;55(1):199-203. Epub 2008 Feb 4.

Department of Biomedical Informatics, Division of Health Science, Osaka University Graduate School of Medicine, Suita, Japan.

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http://dx.doi.org/10.1507/endocrj.k07e-006DOI Listing
March 2008

Evaluation of a chemiluminescent microparticle immunoassay for determination of Treponema pallidum antibodies.

Clin Lab 2007 ;53(9-12):597-603

The Laboratory for Clinical Investigation, Osaka University Hospital, Suita, Japan.

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March 2008

Tissue factor expression on monocytes induced by anti-phospholipid antibodies as a strong risk factor for thromboembolic complications in SLE patients.

Biochem Biophys Res Commun 2008 Jan 5;365(1):195-200. Epub 2007 Nov 5.

Laboratory for Clinical Investigation, Osaka University Hospital, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2007.10.173DOI Listing
January 2008

Ratio of serum IgG3 to total IgG concentration and goiter size are independent factors in intractability of Graves' disease.

Endocr J 2007 Dec 12;54(6):887-94. Epub 2007 Nov 12.

Department of Biomedical Informatics, Division of Health Science, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1507/endocrj.k07-005DOI Listing
December 2007

[Peritoneal lavage diagnosis with TRC (transcription reverse transcription concerted reaction) system for prediction of peritoneal recurrence in gastric cancer].

Rinsho Byori 2007 Nov;55(11):1002-7

Division of Laboratory for Clinical Investigation, Department of Medical Technology, Osaka University Hospital, Suita.

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November 2007

Characteristic changes in platelet-large cell ratio, lactate dehydrogenase and C-reactive protein in thrombocytosis-related diseases.

Acta Haematol 2007 10;118(2):84-7. Epub 2007 Jul 10.

Central Laboratory for Clinical Investigation, Osaka University Hospital, Suita, Osaka, Japan.

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http://dx.doi.org/10.1159/000105167DOI Listing
October 2007

Genetic association of a polymorphism of the cAMP-responsive element binding protein-binding protein with steroid-induced osteonecrosis after kidney transplantation.

J Bone Miner Metab 2007 25;25(5):320-5. Epub 2007 Aug 25.

Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2-D5 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1007/s00774-007-0770-zDOI Listing
October 2007

Evaluation of a model of latent pathologic factors in relation to serum ferritin elevation.

Clin Biochem 2007 Mar 5;40(5-6):359-64. Epub 2007 Jan 5.

Laboratory for Clinical Investigation, Osaka University Hospital, 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.clinbiochem.2006.11.022DOI Listing
March 2007

Apoptosis-induced decrease of intrathyroidal CD4(+)CD25(+) regulatory T cells in autoimmune thyroid diseases.

Thyroid 2007 Jan;17(1):25-31

Division of Biomedical Informatics, Course of Health Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/thy.2006.0231DOI Listing
January 2007

Penicillin susceptibility of non-serotypeable Streptococcus pneumoniae from ophthalmic specimens.

Microb Drug Resist 2006 ;12(3):199-202

Infectious Diseases Laboratory, Department of Health Sciences, School of Medicine, Kyushu University, Fukuoka, 812-8582, Japan.

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http://dx.doi.org/10.1089/mdr.2006.12.199DOI Listing
November 2006

Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-gamma gene.

Endocr J 2006 Aug 5;53(4):473-8. Epub 2006 Jul 5.

Department of Biomedical Informatics, Division of Health Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1507/endocrj.k06-015DOI Listing
August 2006

Urine flow cytometer quantification of leukocytes in samples containing a large proportion of lymphocytes.

Clin Biochem 2006 Aug 26;39(8):857-9. Epub 2006 May 26.

Laboratory for Clinical Investigation, Osaka University Hospital, 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.clinbiochem.2006.05.003DOI Listing
August 2006

The presence of anti-phosphatidylserine/prothrombin antibodies as risk factor for both arterial and venous thrombosis in patients with systemic lupus erythematosus.

Haematologica 2006 May 19;91(5):699-702. Epub 2006 Apr 19.

Laboratory for Clinical Investigation, Osaka University Hospital, Suita, Osaka 565-0871, Japan.

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May 2006

[T3 toxicosis].

Nihon Rinsho 2006 May;Suppl 1:276-8

Department of Biomedical Informatics, Division of Health Science, Osaka University Graduate School of Medicine.

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May 2006

A useful new classification of dysmorphic urinary erythrocytes.

Clin Exp Nephrol 2005 Dec;9(4):304-309

Division of Internal Medicine, Nagoya University Graduate School of Medicine, Aichi, Japan.

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http://dx.doi.org/10.1007/s10157-005-0380-9DOI Listing
December 2005

Multiple SNPs in intron 7 of thyrotropin receptor are associated with Graves' disease.

J Clin Endocrinol Metab 2005 May 1;90(5):2898-903. Epub 2005 Mar 1.

Department of Experimental Therapeutics, Translational Research Center, Kyoto University Hospital, Kyoto University School of Medicine, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1210/jc.2004-2148DOI Listing
May 2005

Inflammation markers and liver dysfunction.

Ann Hematol 2005 Feb 29;84(2):136. Epub 2004 Oct 29.

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http://dx.doi.org/10.1007/s00277-004-0967-3DOI Listing
February 2005

Intrathyroidal CD4+ T lymphocytes express high levels of Fas and CD4+ CD8+ macrophages/dendritic cells express Fas ligand in autoimmune thyroid disease.

Thyroid 2004 Oct;14(10):819-24

Division of Biomedical Informatics, Course of Health Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/thy.2004.14.819DOI Listing
October 2004

[Current topics on immunological laboratory tests-thyroid diseases].

Rinsho Byori 2004 Sep;52(9):751-8

Osaka University Graduate School of Medicine, Course of Health Science, Division of Biomedical Informatics, Suita.

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September 2004

Increased intensities of fas expression on peripheral T-cell subsets in severe autoimmune thyroid disease.

Thyroid 2004 Jun;14(6):417-23

Division of Biomedical Informatics, Course of Health Sciences, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/105072504323150723DOI Listing
June 2004

Increase of serum interleukin-10 in intractable Graves' disease.

Thyroid 2004 Mar;14(3):201-5

Division of Biomedical Informatics, Course of Health Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/105072504773297876DOI Listing
March 2004

A new quality control method based on a moving average of "latent reference values" selected from patients' daily test results.

Rinsho Byori 2004 Mar;52(3):204-11

Laboratory for Clinical Investigation, Osaka University Hospital, Division of Biomedical Informatics, Osaka University, Graduate School of Medicine, Suita 565-0871.

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March 2004

Quantitation of hepatitis B surface antigen by an automated chemiluminescent microparticle immunoassay.

J Virol Methods 2004 Feb;115(2):217-22

The Laboratory for Clinical Investigation, Osaka University Hospital, 2-15 Yamadaoka, Suita-shi, 565-0871, Osaka, Japan.

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http://dx.doi.org/10.1016/j.jviromet.2003.10.002DOI Listing
February 2004

Physiological changes of Fas expression in peripheral lymphocyte subsets during the menstrual cycle.

J Reprod Immunol 2003 Dec;60(2):159-68

Department of Clinical Laboratory Science, School of Allied Health Science, Osaka University, 1-7 Yamada-oka, Suita, 565-0871 Osaka, Japan.

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http://dx.doi.org/10.1016/s0165-0378(03)00107-4DOI Listing
December 2003

[Clinical evaluation of polymerase chain reaction (PCR) method for the detection of hepatitis B virus (HBV)-DNA].

Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi 2003 ;13(2):121-8

Laboratory for Clinical Investigation, Osaka University Hospital, 2-15, Yamadaoka, Suita-shi, Osaka 565-0871, Japan.

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October 2003

Marked decreases of total and immature reticulocytes in myelodysplastic syndrome among patients with pancytopenia.

Acta Haematol 2003 ;109(4):212-3

Central Laboratory for Clinical Investigation, Osaka University Hospital, Suita, Japan.

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http://dx.doi.org/10.1159/000070975DOI Listing
August 2003

Evaluation of MicroScan ESBL confirmation panel for Enterobacteriaceae-producing, extended-spectrum beta-lactamases isolated in Japan.

Diagn Microbiol Infect Dis 2003 Jun;46(2):125-30

Division of Clinical Microbiology, Department of Clinical Pathology, Tenri Hospital, Nara, Japan.

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http://dx.doi.org/10.1016/s0732-8893(03)00041-5DOI Listing
June 2003