Yoshinori Iwatani

Yoshinori Iwatani

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Yoshinori Iwatani

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Association of IFNG gene methylation in peripheral blood cells with the development and prognosis of autoimmune thyroid diseases.

Authors:
Hidemi Hashimoto Mikio Watanabe Naoya Inoue Nachi Hirai Emi Haga Riku Kinoshita Yoh Hidaka Yoshinori Iwatani

Cytokine 2019 Nov 3;123:154770. Epub 2019 Jul 3.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Yamadaoka 1-7, Suita, Osaka 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2019.154770DOI Listing
November 2019

Increases of CD80 and CD86 Expression on Peripheral Blood Cells and their Gene Polymorphisms in Autoimmune Thyroid Disease.

Authors:
Ayano Watanabe Naoya Inoue Mikio Watanabe Mayu Yamamoto Haruka Ozaki Yoh Hidaka Yoshinori Iwatani

Immunol Invest 2019 Nov 22:1-13. Epub 2019 Nov 22.

Department of Biomedical Informatics Division of Health Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1080/08820139.2019.1688343DOI Listing
November 2019

Association of Polymorphisms and its Protein Expression with the Development and Prognosis of Autoimmune Thyroid Diseases.

Authors:
Mayu Yamamoto Mikio Watanabe Naoya Inoue Ayano Watanabe Haruka Ozaki Mizuki Ohsaki Yoh Hidaka Yoshinori Iwatani

Immunol Invest 2019 Sep 11:1-14. Epub 2019 Sep 11.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka , Japan.

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http://dx.doi.org/10.1080/08820139.2019.1659811DOI Listing
September 2019

Association of gene methylation in peripheral blood cells with the development and prognosis of autoimmune thyroid diseases.

Authors:
Nachi Hirai Mikio Watanabe Naoya Inoue Riku Kinoshita Hiroki Ohtani Yoh Hidaka Yoshinori Iwatani

Autoimmunity 2019 Nov - Dec;52(7-8):251-255. Epub 2019 Sep 25.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Suita, Japan.

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http://dx.doi.org/10.1080/08916934.2019.1669568DOI Listing
September 2019

Autoantibodies detected in patients with vitiligo vulgaris but not in those with rhododendrol-induced leukoderma.

Authors:
Noriko Arase Atsushi Tanemura Hui Jin Megumi Nishioka Yumi Aoyama Naoki Oiso Kayoko Matsunaga Tamio Suzuki Chikako Nishigori Tatsuyoshi Kawamura Tadamichi Shimizu Akiko Ito Kazuyoshi Fukai Yuko Abe Lingli Yang Daisuke Tsuruta Keiko Takeoka Yoshinori Iwatani Yoh Hidaka Makoto Nishida Keiko Yamauchi-Takihara Hisashi Arase Manabu Fujimoto Ichiro Katayama

J Dermatol Sci 2019 08 2;95(2):80-83. Epub 2019 Jul 2.

Department of Dermatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 Japan; Department of Pigmentation Research and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, 545-8585 Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2019.06.009DOI Listing
August 2019

Association of current and former smoking with body mass index: A study of smoking discordant twin pairs from 21 twin cohorts.

Authors:
Maarit Piirtola Aline Jelenkovic Antti Latvala Reijo Sund Chika Honda Fujio Inui Mikio Watanabe Rie Tomizawa Yoshinori Iwatani Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde Adam D Tarnoki David L Tarnoki Nicholas G Martin Grant W Montgomery Sarah E Medland Finn Rasmussen Per Tynelius Qihua Tan Dongfeng Zhang Zengchang Pang Esther Rebato Maria A Stazi Corrado Fagnani Sonia Brescianini Andreas Busjahn Jennifer R Harris Ingunn Brandt Thomas Sevenius Nilsen Tessa L Cutler John L Hopper Robin P Corley Brooke M Huibregtse Joohon Sung Jina Kim Jooyeon Lee Sooji Lee Margaret Gatz David A Butler Carol E Franz William S Kremen Michael J Lyons Patrik K E Magnusson Nancy L Pedersen Anna K Dahl Aslan Sevgi Y Öncel Fazil Aliev Catherine A Derom Robert F Vlietinck Ruth J F Loos Judy L Silberg Hermine H Maes Dorret I Boomsma Thorkild I A Sørensen Tellervo Korhonen Jaakko Kaprio Karri Silventoinen

PLoS One 2018 12;13(7):e0200140. Epub 2018 Jul 12.

Department of Social Research, University of Helsinki, Helsinki, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200140PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042712PMC
January 2019

Toll-like receptor 4 promoter polymorphisms in a familial mediterranean fever patient with asymptomatic bacteriuria.

Authors:
Shinichiro Kawamoto Ryota Masutani Keiji Kurata Etsuko Shima Yoshinori Iwatani Takayuki Takubo

Clin Case Rep 2019 Jan 25;7(1):155-159. Epub 2018 Nov 25.

Japanese Red Cross Society Osaka Japan.

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http://doi.wiley.com/10.1002/ccr3.1941
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http://dx.doi.org/10.1002/ccr3.1941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333084PMC
January 2019

Polymorphisms in Th17-related genes and the pathogenesis of autoimmune thyroid disease.

Authors:
Takayuki Kunisato Mikio Watanabe Naoya Inoue Azusa Okada Takashi Nanba Wataru Kobayashi Yuka Inoue Yuka Katsumata Naoki Omori Takayuki Nobuhara Kazuya Takemura Yoh Hidaka Yoshinori Iwatani

Autoimmunity 2018 Nov 24:1-10. Epub 2018 Nov 24.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Osaka , Japan.

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https://www.tandfonline.com/doi/full/10.1080/08916934.2018.1
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http://dx.doi.org/10.1080/08916934.2018.1534963DOI Listing
November 2018

Association of the polymorphisms in Th2 chemotaxis-related genes with the development and prognosis of autoimmune thyroid diseases.

Authors:
Naoki Omori Mikio Watanabe Naoya Inoue Junpei Taniguchi Yoh Hidaka Yoshinori Iwatani

Endocr J 2018 Aug 30;65(8):815-826. Epub 2018 May 30.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

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https://www.jstage.jst.go.jp/article/endocrj/65/8/65_EJ18-00
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http://dx.doi.org/10.1507/endocrj.EJ18-0050DOI Listing
August 2018

Functional Polymorphisms of the Type 1 and Type 2 Iodothyronine Deiodinase Genes in Autoimmune Thyroid Diseases.

Authors:
Naoya Inoue Mikio Watanabe Yuka Katsumata Naoko Ishido Yoh Hidaka Yoshinori Iwatani

Immunol Invest 2018 Jul 12;47(5):534-542. Epub 2018 Apr 12.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Osaka , Japan.

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http://dx.doi.org/10.1080/08820139.2018.1458861DOI Listing
July 2018

Methylation levels of the TNFA gene are different between Graves' and Hashimoto's diseases and influenced by the TNFA polymorphism.

Authors:
Emi Morita Mikio Watanabe Naoya Inoue Hidemi Hashimoto Emi Haga Yoh Hidaka Yoshinori Iwatani

Autoimmunity 2018 05 11;51(3):118-125. Epub 2018 Mar 11.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.

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http://dx.doi.org/10.1080/08916934.2018.1448078DOI Listing
May 2018

Mean platelet component and mean platelet volume as useful screening markers for myelodysplastic syndrome.

Authors:
Ryota Masutani Toshiyuki Ikemoto Ayako Maki Hiroko Tanada Yoshinori Iwatani Mikio Watanabe Takayuki Takubo Yoshikatsu Okada

Health Sci Rep 2018 May 2;1(5):e50. Epub 2018 May 2.

Department of Central Clinical Laboratory Osaka Medical College Hospital Takatsuki Osaka Japan.

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http://dx.doi.org/10.1002/hsr2.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266360PMC
May 2018

Polymorphisms and expression of genes encoding Argonautes 1 and 2 in autoimmune thyroid diseases.

Authors:
Ena Tokiyoshi Mikio Watanabe Naoya Inoue Yoh Hidaka Yoshinori Iwatani

Autoimmunity 2018 02 19;51(1):35-42. Epub 2017 Dec 19.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.

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http://dx.doi.org/10.1080/08916934.2017.1416468DOI Listing
February 2018

Establishment and characterization of a novel Hodgkin lymphoma cell line, AM-HLH, carrying the Epstein-Barr virus genome integrated into the host chromosome.

Authors:
Masahiko Hayashida Masanori Daibata Erika Tagami Takahiro Taguchi Fumiyo Maekawa Kayo Takeoka Katsuhiro Fukutsuka Daiki Shimomura Takamasa Hayashi Yoshinori Iwatani Hitoshi Ohno

Hematol Oncol 2017 Dec 4;35(4):567-575. Epub 2016 Nov 4.

Tenri Institute of Medical Research, Tenri, Japan.

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http://dx.doi.org/10.1002/hon.2369DOI Listing
December 2017

Frequency-specific genetic influence on inferior parietal lobule activation commonly observed during action observation and execution.

Authors:
Toshihiko Araki Mai Onishi Takufumi Yanagisawa Masayuki Hirata Yoshiyuki Watanabe Soshiro Ogata Kazuo Hayakawa Chika Honda Mikio Watanabe Yoshinori Iwatani Shiro Yorifuji

Sci Rep 2017 12 15;7(1):17660. Epub 2017 Dec 15.

Division of Functional Diagnostic Science, Graduate School of Medicine, Osaka University, Osaka, 565-0871, Japan.

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http://dx.doi.org/10.1038/s41598-017-17662-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732255PMC
December 2017

Genotype-based epigenetic differences in monozygotic twins discordant for positive anti-thyroglobulin autoantibodies.

Authors:
Mikio Watanabe Yoichi Takenaka Chika Honda Yoshinori Iwatani

Thyroid 2017 11 4. Epub 2017 Nov 4.

Osaka University Graduate School of Medicine, Division of Health Sciences, Department of Biomedical Informatics, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/thy.2017.0273DOI Listing
November 2017

The polymorphisms in the thyroid peroxidase gene were associated with the development of autoimmune thyroid disease and the serum levels of anti-thyroid peroxidase antibody.

Authors:
Saki Tomari Mikio Watanabe Naoya Inoue Tomoyo Mizuma Chika Yamanaka Yoh Hidaka Yoshinori Iwatani

Endocr J 2017 Oct 25;64(10):1025-1032. Epub 2017 Aug 25.

Department of Biomedical Informatics Division of Health Sciences Osaka University Graduate School of Medicine, Suita 565-0871, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ17-0191DOI Listing
October 2017

Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts.

Authors:
Karri Silventoinen Aline Jelenkovic Antti Latvala Reijo Sund Yoshie Yokoyama Vilhelmina Ullemar Catarina Almqvist Catherine A Derom Robert F Vlietinck Ruth J F Loos Christian Kandler Chika Honda Fujio Inui Yoshinori Iwatani Mikio Watanabe Esther Rebato Maria A Stazi Corrado Fagnani Sonia Brescianini Yoon-Mi Hur Hoe-Uk Jeong Tessa L Cutler John L Hopper Andreas Busjahn Kimberly J Saudino Fuling Ji Feng Ning Zengchang Pang Richard J Rose Markku Koskenvuo Kauko Heikkilä Wendy Cozen Amie E Hwang Thomas M Mack Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Fruhling Rijsdijk Joohon Sung Jina Kim Jooyeon Lee Sooji Lee Tracy L Nelson Keith E Whitfield Qihua Tan Dongfeng Zhang Clare H Llewellyn Abigail Fisher S Alexandra Burt Kelly L Klump Ariel Knafo-Noam David Mankuta Lior Abramson Sarah E Medland Nicholas G Martin Grant W Montgomery Patrik K E Magnusson Nancy L Pedersen Anna K Dahl Aslan Robin P Corley Brooke M Huibregtse Sevgi Y Öncel Fazil Aliev Robert F Krueger Matt McGue Shandell Pahlen Gonneke Willemsen Meike Bartels Catharina E M van Beijsterveldt Judy L Silberg Lindon J Eaves Hermine H Maes Jennifer R Harris Ingunn Brandt Thomas S Nilsen Finn Rasmussen Per Tynelius Laura A Baker Catherine Tuvblad Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde Margaret Gatz David A Butler Paul Lichtenstein Jack H Goldberg K Paige Harden Elliot M Tucker-Drob Glen E Duncan Dedra Buchwald Adam D Tarnoki David L Tarnoki Carol E Franz William S Kremen Michael J Lyons José A Maia Duarte L Freitas Eric Turkheimer Thorkild I A Sørensen Dorret I Boomsma Jaakko Kaprio

Twin Res Hum Genet 2017 10;20(5):395-405

Institute for Molecular Medicine FIMM,Helsinki,Finland.

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http://dx.doi.org/10.1017/thg.2017.49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969906PMC
October 2017

Association of the polymorphisms in the gene encoding thyroglobulin with the development and prognosis of autoimmune thyroid disease.

Authors:
Tomoyo Mizuma Mikio Watanabe Naoya Inoue Yuya Arakawa Saki Tomari Yoh Hidaka Yoshinori Iwatani

Autoimmunity 2017 Sep 4;50(6):386-392. Epub 2017 Jul 4.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Osaka , Japan.

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http://dx.doi.org/10.1080/08916934.2017.1344971DOI Listing
September 2017

Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts.

Authors:
Karri Silventoinen Aline Jelenkovic Reijo Sund Yoshie Yokoyama Yoon-Mi Hur Wendy Cozen Amie E Hwang Thomas M Mack Chika Honda Fujio Inui Yoshinori Iwatani Mikio Watanabe Rie Tomizawa Kirsi H Pietiläinen Aila Rissanen Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Fruhling Rijsdijk Qihua Tan Dongfeng Zhang Zengchang Pang Maarit Piirtola Sari Aaltonen Sevgi Y Öncel Fazil Aliev Esther Rebato Jacob B Hjelmborg Kaare Christensen Axel Skytthe Kirsten O Kyvik Judy L Silberg Lindon J Eaves Tessa L Cutler Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde Yun-Mi Song Sarah Yang Kayoung Lee Carol E Franz William S Kremen Michael J Lyons Andreas Busjahn Tracy L Nelson Keith E Whitfield Christian Kandler Kerry L Jang Margaret Gatz David A Butler Maria A Stazi Corrado Fagnani Cristina D'Ippolito Glen E Duncan Dedra Buchwald Nicholas G Martin Sarah E Medland Grant W Montgomery Hoe-Uk Jeong Gary E Swan Ruth Krasnow Patrik Ke Magnusson Nancy L Pedersen Anna K Dahl Aslan Tom A McAdams Thalia C Eley Alice M Gregory Per Tynelius Laura A Baker Catherine Tuvblad Gombojav Bayasgalan Danshiitsoodol Narandalai Timothy D Spector Massimo Mangino Genevieve Lachance S Alexandra Burt Kelly L Klump Jennifer R Harris Ingunn Brandt Thomas S Nilsen Robert F Krueger Matt McGue Shandell Pahlen Robin P Corley Brooke M Huibregtse Meike Bartels Catharina Em van Beijsterveldt Gonneke Willemsen Jack H Goldberg Finn Rasmussen Adam D Tarnoki David L Tarnoki Catherine A Derom Robert F Vlietinck Ruth Jf Loos John L Hopper Joohon Sung Hermine H Maes Eric Turkheimer Dorret I Boomsma Thorkild Ia Sørensen Jaakko Kaprio

Am J Clin Nutr 2017 Aug 5;106(2):457-466. Epub 2017 Jul 5.

Public Health, and.

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http://dx.doi.org/10.3945/ajcn.117.153643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525120PMC
August 2017

Association of IL-10-Regulating MicroRNAs in Peripheral Blood Mononuclear Cells with the Pathogenesis of Autoimmune Thyroid Disease.

Authors:
Yukina Takuse Mikio Watanabe Naoya Inoue Ritsuko Ozaki Hiroshi Ohtsu Minori Saeki Yuka Katsumata Yoh Hidaka Yoshinori Iwatani

Immunol Invest 2017 Aug 25;46(6):590-602. Epub 2017 Jul 25.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Suita , Osaka , Japan.

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http://dx.doi.org/10.1080/08820139.2017.1322975DOI Listing
August 2017

Functional polymorphisms affecting Th1 differentiation are associated with the severity of autoimmune thyroid diseases.

Authors:
Naoya Inoue Mikio Watanabe Azusa Nakaguchi Daishi Ueda Hayaka Kawaguti Yoh Hidaka Yoshinori Iwatani

Endocr J 2017 Jul 16;64(7):695-703. Epub 2017 May 16.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ16-0551DOI Listing
July 2017

Polymorphisms and expression of toll-like receptors in autoimmune thyroid diseases.

Authors:
Naoya Inoue Yuka Katsumata Mikio Watanabe Naoko Ishido Yu Manabe Ayano Watanabe Ryota Masutani Yoh Hidaka Yoshinori Iwatani

Autoimmunity 2017 May 26;50(3):182-191. Epub 2016 Dec 26.

a Department of Biomedical Informatics , Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka , Japan and.

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http://dx.doi.org/10.1080/08916934.2016.1261835DOI Listing
May 2017

Intraindividual variation of microRNA expression levels in plasma and peripheral blood mononuclear cells and the associations of these levels with the pathogenesis of autoimmune thyroid diseases.

Authors:
Hiroshi Otsu Mikio Watanabe Naoya Inoue Ryota Masutani Yoshinori Iwatani

Clin Chem Lab Med 2017 May;55(5):626-635

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Yamadaoka 1-7 Suita, Osaka 565-0871.

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http://dx.doi.org/10.1515/cclm-2016-0449DOI Listing
May 2017

TSHR Gene Polymorphisms in the Enhancer Regions Are Most Strongly Associated with the Development of Graves' Disease, Especially Intractable Disease, and of Hashimoto's Disease.

Authors:
Asami Fujii Naoya Inoue Mikio Watanabe Chisa Kawakami Yoh Hidaka Yoshihide Hayashizaki Yoshinori Iwatani

Thyroid 2017 01 18;27(1):111-119. Epub 2016 Nov 18.

1 Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka, Japan .

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http://dx.doi.org/10.1089/thy.2016.0345DOI Listing
January 2017

DICER and DROSHA gene expression and polymorphisms in autoimmune thyroid diseases.

Authors:
Minori Saeki Mikio Watanabe Naoya Inoue Ena Tokiyoshi Yukina Takuse Yuya Arakawa Yoh Hidaka Yoshinori Iwatani

Autoimmunity 2016 12 3;49(8):514-522. Epub 2016 Nov 3.

a Department of Biomedical Informatics, Division of Health Sciences , Osaka University Graduate School of Medicine , Osaka , Japan and.

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http://dx.doi.org/10.1080/08916934.2016.1230846DOI Listing
December 2016

Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994.

Authors:
Aline Jelenkovic Yoon-Mi Hur Reijo Sund Yoshie Yokoyama Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Fruhling Rijsdijk Qihua Tan Dongfeng Zhang Zengchang Pang Sari Aaltonen Kauko Heikkilä Sevgi Y Öncel Fazil Aliev Esther Rebato Adam D Tarnoki David L Tarnoki Kaare Christensen Axel Skytthe Kirsten O Kyvik Judy L Silberg Lindon J Eaves Hermine H Maes Tessa L Cutler John L Hopper Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde Wendy Cozen Amie E Hwang Thomas M Mack Joohon Sung Yun-Mi Song Sarah Yang Kayoung Lee Carol E Franz William S Kremen Michael J Lyons Andreas Busjahn Tracy L Nelson Keith E Whitfield Christian Kandler Kerry L Jang Margaret Gatz David A Butler Maria A Stazi Corrado Fagnani Cristina D'Ippolito Glen E Duncan Dedra Buchwald Catherine A Derom Robert F Vlietinck Ruth Jf Loos Nicholas G Martin Sarah E Medland Grant W Montgomery Hoe-Uk Jeong Gary E Swan Ruth Krasnow Patrik Ke Magnusson Nancy L Pedersen Anna K Dahl-Aslan Tom A McAdams Thalia C Eley Alice M Gregory Per Tynelius Laura A Baker Catherine Tuvblad Gombojav Bayasgalan Danshiitsoodol Narandalai Paul Lichtenstein Timothy D Spector Massimo Mangino Genevieve Lachance Meike Bartels Toos Cem van Beijsterveldt Gonneke Willemsen S Alexandra Burt Kelly L Klump Jennifer R Harris Ingunn Brandt Thomas Sevenius Nilsen Robert F Krueger Matt McGue Shandell Pahlen Robin P Corley Jacob V B Hjelmborg Jack H Goldberg Yoshinori Iwatani Mikio Watanabe Chika Honda Fujio Inui Finn Rasmussen Brooke M Huibregtse Dorret I Boomsma Thorkild I A Sørensen Jaakko Kaprio Karri Silventoinen

Elife 2016 12 14;5. Epub 2016 Dec 14.

Department of Social Research, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.7554/eLife.20320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156525PMC
December 2016

Optimization of Recovery and Analysis of RNA in Sorted Cells in mRNA Quantification After Fluorescence-activated Cell Sorting.

Authors:
Tomoko Maeda Arisa Date Mikio Watanabe Yoh Hidaka Yoshinori Iwatani Toru Takano

Ann Clin Lab Sci 2016 Dec;46(6):571-577

Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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December 2016

Association of polymorphisms in the ICOS and ICOSL genes with the pathogenesis of autoimmune thyroid diseases.

Authors:
Namiki Yoshie Mikio Watanabe Naoya Inoue Hayaka Kawaguchi Yoh Hidaka Yoshinori Iwatani

Endocr J 2016 12;63(1):61-8. Epub 2015 Nov 12.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ15-0435DOI Listing
November 2016

Involvement of genes encoding apoptosis regulatory factors (FAS, FASL, TRAIL, BCL2, TNFR1 and TNFR2) in the pathogenesis of autoimmune thyroid diseases.

Authors:
Naoya Inoue Mikio Watanabe Naoko Ishido Arisa Kodu Hayato Maruoka Yuka Katsumata Yoh Hidaka Yoshinori Iwatani

Hum Immunol 2016 Oct 22;77(10):944-951. Epub 2016 Jul 22.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University, Graduate School of Medicine, 1-7 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.humimm.2016.07.232DOI Listing
October 2016

Association between functional SIRT1 polymorphisms and the clinical characteristics of patients with autoimmune thyroid disease.

Authors:
Mika Sarumaru Mikio Watanabe Naoya Inoue Yuko Hisamoto Emi Morita Yuya Arakawa Yoh Hidaka Yoshinori Iwatani

Autoimmunity 2016 08 31;49(5):329-37. Epub 2016 May 31.

a Department of Biomedical Informatics , Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka , Japan and.

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http://dx.doi.org/10.3109/08916934.2015.1134506DOI Listing
August 2016

Association of the polymorphisms of chemokine genes (IL8, RANTES, MIG, IP10, MCP1 and IL16) with the pathogenesis of autoimmune thyroid diseases.

Authors:
Maiko Akahane Mikio Watanabe Naoya Inoue Yumi Miyahara Yuya Arakawa Yuka Inoue Yuka Katsumata Yoh Hidaka Yoshinori Iwatani

Autoimmunity 2016 08 31;49(5):312-9. Epub 2016 May 31.

a Department of Biomedical Informatics , Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka , Japan and.

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http://dx.doi.org/10.3109/08916934.2015.1134507DOI Listing
August 2016

Within-pair differences of DNA methylation levels between monozygotic twins are different between male and female pairs.

Authors:
Mikio Watanabe Chika Honda Yoshinori Iwatani Shiro Yorifuji Hiroyasu Iso Kei Kamide Jun Hatazawa Shinji Kihara Norio Sakai Hiroko Watanabe Kiyoko Makimoto Mikio Watanabe Chika Honda Yoshinori Iwatani

BMC Med Genomics 2016 08 26;9(1):55. Epub 2016 Aug 26.

Department of Biomedical Informatics, Osaka University Graduate School of Medicine, Yamadaoka 1-7, Suita, Osaka, 565-0871, Japan.

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http://dx.doi.org/10.1186/s12920-016-0217-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000519PMC
August 2016

Increases of microRNA let-7e in peripheral blood mononuclear cells in Hashimoto's disease.

Authors:
Tomoya Kagawa Mikio Watanabe Naoya Inoue Hiroshi Otsu Minori Saeki Yuka Katsumata Yukina Takuse Yoshinori Iwatani

Endocr J 2016 Apr 28;63(4):375-80. Epub 2016 Jan 28.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ15-0577DOI Listing
April 2016

Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project.

Authors:
Aline Jelenkovic Yoshie Yokoyama Reijo Sund Chika Honda Leonie H Bogl Sari Aaltonen Fuling Ji Feng Ning Zengchang Pang Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde S Alexandra Burt Kelly L Klump Sarah E Medland Grant W Montgomery Christian Kandler Tom A McAdams Thalia C Eley Alice M Gregory Kimberly J Saudino Lise Dubois Michel Boivin Adam D Tarnoki David L Tarnoki Claire M A Haworth Robert Plomin Sevgi Y Öncel Fazil Aliev Maria A Stazi Corrado Fagnani Cristina D'Ippolito Jeffrey M Craig Richard Saffery Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Fruhling Rijsdijk Timothy Spector Massimo Mangino Genevieve Lachance Margaret Gatz David A Butler Gombojav Bayasgalan Danshiitsoodol Narandalai Duarte L Freitas José Antonio Maia K Paige Harden Elliot M Tucker-Drob Bia Kim Youngsook Chong Changhee Hong Hyun Jung Shin Kaare Christensen Axel Skytthe Kirsten O Kyvik Catherine A Derom Robert F Vlietinck Ruth J F Loos Wendy Cozen Amie E Hwang Thomas M Mack Mingguang He Xiaohu Ding Billy Chang Judy L Silberg Lindon J Eaves Hermine H Maes Tessa L Cutler John L Hopper Kelly Aujard Patrik K E Magnusson Nancy L Pedersen Anna K Dahl Aslan Yun-Mi Song Sarah Yang Kayoung Lee Laura A Baker Catherine Tuvblad Morten Bjerregaard-Andersen Henning Beck-Nielsen Morten Sodemann Kauko Heikkilä Qihua Tan Dongfeng Zhang Gary E Swan Ruth Krasnow Kerry L Jang Ariel Knafo-Noam David Mankuta Lior Abramson Paul Lichtenstein Robert F Krueger Matt McGue Shandell Pahlen Per Tynelius Glen E Duncan Dedra Buchwald Robin P Corley Brooke M Huibregtse Tracy L Nelson Keith E Whitfield Carol E Franz William S Kremen Michael J Lyons Syuichi Ooki Ingunn Brandt Thomas Sevenius Nilsen Fujio Inui Mikio Watanabe Meike Bartels Toos C E M van Beijsterveldt Jane Wardle Clare H Llewellyn Abigail Fisher Esther Rebato Nicholas G Martin Yoshinori Iwatani Kazuo Hayakawa Joohon Sung Jennifer R Harris Gonneke Willemsen Andreas Busjahn Jack H Goldberg Finn Rasmussen Yoon-Mi Hur Dorret I Boomsma Thorkild I A Sørensen Jaakko Kaprio Karri Silventoinen

Twin Res Hum Genet 2015 Oct 4;18(5):557-70. Epub 2015 Sep 4.

Department of Social Research,University of Helsinki,Helsinki,Finland.

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http://dx.doi.org/10.1017/thg.2015.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605819PMC
October 2015

The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits.

Authors:
Karri Silventoinen Aline Jelenkovic Reijo Sund Chika Honda Sari Aaltonen Yoshie Yokoyama Adam D Tarnoki David L Tarnoki Feng Ning Fuling Ji Zengchang Pang Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde S Alexandra Burt Kelly L Klump Sarah E Medland Grant W Montgomery Christian Kandler Tom A McAdams Thalia C Eley Alice M Gregory Kimberly J Saudino Lise Dubois Michel Boivin Claire M A Haworth Robert Plomin Sevgi Y Öncel Fazil Aliev Maria A Stazi Corrado Fagnani Cristina D'Ippolito Jeffrey M Craig Richard Saffery Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Timothy Spector Massimo Mangino Genevieve Lachance Margaret Gatz David A Butler Gombojav Bayasgalan Danshiitsoodol Narandalai Duarte L Freitas José Antonio Maia K Paige Harden Elliot M Tucker-Drob Kaare Christensen Axel Skytthe Kirsten O Kyvik Changhee Hong Youngsook Chong Catherine A Derom Robert F Vlietinck Ruth J F Loos Wendy Cozen Amie E Hwang Thomas M Mack Mingguang He Xiaohu Ding Billy Chang Judy L Silberg Lindon J Eaves Hermine H Maes Tessa L Cutler John L Hopper Kelly Aujard Patrik K E Magnusson Nancy L Pedersen Anna K Dahl Aslan Yun-Mi Song Sarah Yang Kayoung Lee Laura A Baker Catherine Tuvblad Morten Bjerregaard-Andersen Henning Beck-Nielsen Morten Sodemann Kauko Heikkilä Qihua Tan Dongfeng Zhang Gary E Swan Ruth Krasnow Kerry L Jang Ariel Knafo-Noam David Mankuta Lior Abramson Paul Lichtenstein Robert F Krueger Matt McGue Shandell Pahlen Per Tynelius Glen E Duncan Dedra Buchwald Robin P Corley Brooke M Huibregtse Tracy L Nelson Keith E Whitfield Carol E Franz William S Kremen Michael J Lyons Syuichi Ooki Ingunn Brandt Thomas Sevenius Nilsen Fujio Inui Mikio Watanabe Meike Bartels Toos C E M van Beijsterveldt Jane Wardle Clare H Llewellyn Abigail Fisher Esther Rebato Nicholas G Martin Yoshinori Iwatani Kazuo Hayakawa Finn Rasmussen Joohon Sung Jennifer R Harris Gonneke Willemsen Andreas Busjahn Jack H Goldberg Dorret I Boomsma Yoon-Mi Hur Thorkild I A Sørensen Jaakko Kaprio

Twin Res Hum Genet 2015 Aug 27;18(4):348-60. Epub 2015 May 27.

Department of Public Health,University of Helsinki,Helsinki,Finland.

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http://www.journals.cambridge.org/abstract_S1832427415000298
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http://dx.doi.org/10.1017/thg.2015.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696543PMC
August 2015

Performance evaluation of four dominant anti-hepatitis B core antigen (HBcAb) kits in Japan for preventing de novo hepatitis B virus (HBV) infection.

Authors:
Eiji Kobayashi Matsuo Deguchi Masanori Kagita Nori Yoshioka Mifumi Kita Seishi Asari Etsuji Suehisa Yoh Hidaka Yoshinori Iwatani

Clin Lab 2015 ;61(1-2):77-85

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http://dx.doi.org/10.7754/Clin.Lab.2014.140504DOI Listing
April 2015

The relationship between skewed X chromosome inactivation and the prognosis of Graves' and Hashimoto's diseases.

Authors:
Naoko Ishido Naoya Inoue Mikio Watanabe Yoh Hidaka Yoshinori Iwatani

Thyroid 2015 Feb 10;25(2):256-61. Epub 2014 Dec 10.

1 Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine , Osaka, Japan .

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http://dx.doi.org/10.1089/thy.2014.0318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322037PMC
February 2015

Clinical usefulness of the PAXgene™ bone marrow RNA system for stabilizing total RNA.

Authors:
Mayu Takeda Tadao Funato Masaki Ikemoto Toru Nanmoku Yoshimasa Urasaki Yoshinori Iwatani

J Clin Lab Anal 2015 Jan 28;29(1):61-7. Epub 2014 Mar 28.

Department of Clinical Laboratory Science, Faculty of Health Care, Tenri Health Care University, Tenri, Japan; Department of Biomedical Informatics, Division of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.

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http://dx.doi.org/10.1002/jcla.21729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807000PMC
January 2015

In vitro evaluations of topical agents to treat Acanthamoeba keratitis.

Authors:
Atsuko Sunada Keigo Kimura Isao Nishi Masahiro Toyokawa Akiko Ueda Tomomi Sakata Takashi Suzuki Yoshitsugu Inoue Yuichi Ohashi Seishi Asari Yoshinori Iwatani

Ophthalmology 2014 Oct 29;121(10):2059-65. Epub 2014 May 29.

Department of Ophthalmology, Ehime University School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1016/j.ophtha.2014.04.013DOI Listing
October 2014

The GG genotype of the -1125G/T polymorphism in the EPO gene protects against the development of Graves' disease.

Authors:
Naoya Inoue Mikio Watanabe Takayuki Nobuhara Yoh Hidaka Yoshinori Iwatani

Immunol Lett 2013 Nov-Dec;156(1-2):156-8. Epub 2013 Oct 28.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Yamadaoka 1-7, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.imlet.2013.10.006DOI Listing
July 2014

An improved protocol for mRNA quantification after fluorescence-activated cell sorting with an increased signal to noise ratio in flow cytometry.

Authors:
Arisa Date Tomoko Maeda Mikio Watanabe Yoh Hidaka Yoshinori Iwatani Toru Takano

Mol Biotechnol 2014 Jul;56(7):591-8

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, D2, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

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http://dx.doi.org/10.1007/s12033-014-9733-5DOI Listing
July 2014

[Relationship between serum hCG and urinary hCG in cases of pregnancy, abortion, and hydatidiform mole].

Authors:
Yoshizumi Kishino Yuji Tanaka Kenichi Nakae Yoshinori Iwatani Toshinori Kamisako

Rinsho Byori 2014 Jan;62(1):38-44

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January 2014

IL-10 -592A/C polymorphism is associated with severity of Hashimoto's disease.

Authors:
Naoya Inoue Mikio Watanabe Megumi Wada Mami Morita Yoh Hidaka Yoshinori Iwatani

Cytokine 2013 Oct 10;64(1):370-4. Epub 2013 Jun 10.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Yamadaoka 1-7, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.cyto.2013.05.014DOI Listing
October 2013

Ezetimibe increases hepatic iron levels in mice fed a high-fat diet.

Authors:
Yoshizumi Kishino Yuji Tanaka Takanori Ikeda Kazuo Yamamoto Hiroshi Ogawa Yoshinori Iwatani Toshinori Kamisako

J Pharmacol Exp Ther 2013 Jun 28;345(3):483-91. Epub 2013 Mar 28.

Department of Clinical Laboratory Medicine, Kinki University Faculty of Medicine, 377-2, Ohnohigashi, Osakasayama 589-8511, Japan.

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http://dx.doi.org/10.1124/jpet.113.203448DOI Listing
June 2013

Preparation of thyroid follicular cells for mRNA quantification after fluorescence-activated cell sorting.

Authors:
Chisa Matsumoto Mitsuru Ito Hiroya Yamada Hiroshi Yoshida Mikio Watanabe Yoh Hidaka Yoshinori Iwatani Akira Miyauch Toru Takano

Scand J Clin Lab Invest 2013 Apr 2;73(3):245-52. Epub 2013 Apr 2.

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.3109/00365513.2013.769624DOI Listing
April 2013

Genes that characterize T3-predominant Graves' thyroid tissues.

Authors:
Chisa Matsumoto Mitsuru Ito Hiroya Yamada Noriko Yamakawa Hiroshi Yoshida Arisa Date Mikio Watanabe Yoh Hidaka Yoshinori Iwatani Akira Miyauchi Toru Takano

Eur J Endocrinol 2013 Feb 17;168(2):137-44. Epub 2013 Jan 17.

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, D2, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1530/EJE-12-0507DOI Listing
February 2013

Interference by pralidoxime (PAM) salts in clinical laboratory tests.

Authors:
Sumika Nagase Katsunori Kohguchi Kaoru Tohyama Mikio Watanabe Yoshinori Iwatani

Clin Chim Acta 2013 Feb 27;416:72-9. Epub 2012 Nov 27.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00098981120055
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http://dx.doi.org/10.1016/j.cca.2012.11.017DOI Listing
February 2013

An overview of multidisciplinary research resources at the Osaka University Center for Twin Research.

Authors:
Kazuo Hayakawa Yoshinori Iwatani

Twin Res Hum Genet 2013 Feb 8;16(1):217-20. Epub 2013 Jan 8.

Center for Twin Research, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1017/thg.2012.141DOI Listing
February 2013

Measurement of TFF3 mRNA in aspirates from thyroid nodules using mesh filtration: the first clinical trial in 130 cases.

Authors:
Hiroya Yamada Toru Takano Minoru Kihara Mitsuyoshi Hirokawa Hiroshi Yoshida Mikio Watanabe Yoshinori Iwatani Yoh Hidaka Akira Miyauchi

Endocr J 2012 26;59(7):621-30. Epub 2012 May 26.

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.

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http://dx.doi.org/10.1507/endocrj.ej12-0077DOI Listing
January 2013

Associations between autoimmune thyroid disease prognosis and functional polymorphisms of susceptibility genes, CTLA4, PTPN22, CD40, FCRL3, and ZFAT, previously revealed in genome-wide association studies.

Authors:
Naoya Inoue Mikio Watanabe Hiroya Yamada Kazuya Takemura Fumiaki Hayashi Noriko Yamakawa Maiko Akahane Yu Shimizuishi Yoh Hidaka Yoshinori Iwatani

J Clin Immunol 2012 Dec 17;32(6):1243-52. Epub 2012 Jun 17.

Department of Biomedical Informatics, Division of Health Sciences, Graduate School of Medicine, Osaka University, Yamadaoka 1-7, Suita, Osaka, Japan.

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http://dx.doi.org/10.1007/s10875-012-9721-0DOI Listing
December 2012

[FACS-mQ as a powerful clinical test in the cancer stem cell era].

Authors:
Toru Takano Yoh Hidaka Yoshinori Iwatani

Rinsho Byori 2012 Aug;60(8):748-52

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.

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August 2012

Functional polymorphisms in TBX21 and HLX are associated with development and prognosis of Graves' disease.

Authors:
Mami Morita Mikio Watanabe Naoya Inoue Chisa Inaoka Takashi Akamizu Ke-Ita Tatsumi Yoh Hidaka Yoshinori Iwatani

Autoimmunity 2012 Mar 21;45(2):129-36. Epub 2011 Oct 21.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.3109/08916934.2011.622013DOI Listing
March 2012

A solution for distinguishing Le(a-b-) sera in CA19-9 assays using SphereLight 180 and Architect i2000 assays.

Authors:
Hiroyuki Hanada Satomi Mugii Keiko Takeoka Ikuhiro Maeda Mikio Watanabe Yoh Hidaka Yoshinori Iwatani

Clin Chim Acta 2012 Jan 14;413(1-2):278-81. Epub 2011 Sep 14.

Division of Laboratory for Clinical Investigation, Department of Medical Technology, Osaka University Hospital, Suita, Osaka, Japan.

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http://dx.doi.org/10.1016/j.cca.2011.09.009DOI Listing
January 2012

mRNA quantification after fluorescence activated cell sorting using locked nucleic acid probes.

Authors:
Rie Maruo Hiroya Yamada Mikio Watanabe Yoh Hidaka Yoshinori Iwatani Toru Takano

Mol Biotechnol 2011 Sep;49(1):42-7

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, D2, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

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http://link.springer.com/10.1007/s12033-011-9375-9
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http://dx.doi.org/10.1007/s12033-011-9375-9DOI Listing
September 2011

Transcriptional activity of the 5'-flanking region of the thyroid transcription factor-1 gene in human thyroid cell lines.

Authors:
Hiroya Yamada Toru Takano Fumio Matsuzuka Mikio Watanabe Akira Miyauchi Yoshinori Iwatani

Genet Mol Biol 2011 Jan 1;34(1):6-10. Epub 2011 Mar 1.

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1590/S1415-47572010005000109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085375PMC
January 2011

Messenger RNA quantification after fluorescence-activated cell sorting using in situ hybridization.

Authors:
Hiroya Yamada Rie Maruo Mikio Watanabe Yoh Hidaka Yoshinori Iwatani Toru Takano

Cytometry A 2010 Nov;77(11):1032-7

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

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http://doi.wiley.com/10.1002/cyto.a.20973
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http://dx.doi.org/10.1002/cyto.a.20973DOI Listing
November 2010

Messenger RNA quantification after fluorescence activated cell sorting using intracellular antigens.

Authors:
Hiroya Yamada Rie Maruo Mikio Watanabe Yoh Hidaka Yoshinori Iwatani Toru Takano

Biochem Biophys Res Commun 2010 Jul 27;397(3):425-8. Epub 2010 May 27.

Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2010.05.112DOI Listing
July 2010

Increases in urinary creatinine and blood pressure during early pregnancy in pre-eclampsia.

Authors:
Koichi Kuromoto Mikio Watanabe Kazushige Adachi Kazutomo Ohashi Yoshinori Iwatani

Ann Clin Biochem 2010 Jul 28;47(Pt 4):336-42. Epub 2010 May 28.

Department of Biomedical Informatics, Division of Health Sciences, Graduate School of Medicine, Osaka University, Japan.

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http://dx.doi.org/10.1258/acb.2010.090290DOI Listing
July 2010

Postpartum increase of serum thioredoxin concentrations and the relation to CD8 lymphocytes.

Authors:
Shoko Kuroda Mikio Watanabe Tomoko Santo Yu Shimizuishi Toru Takano Yoh Hidaka Tadashi Kimura Yoshinori Iwatani

Ann Clin Biochem 2010 Jan 25;47(Pt 1):62-6. Epub 2009 Nov 25.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1258/acb.2009.009120DOI Listing
January 2010

Expression of nestin mRNA is a differentiation marker in thyroid tumors.

Authors:
Hiroya Yamada Toru Takano Yasuhiro Ito Fumio Matsuzuka Akihiro Miya Kaoru Kobayashi Hiroshi Yoshida Mikio Watanabe Yoshinori Iwatani Akira Miyauchi

Cancer Lett 2009 Jul 5;280(1):61-4. Epub 2009 Mar 5.

Department of Laboratory Medicine, Osaka University Medical School, 2-2 D2, Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.canlet.2009.02.006DOI Listing
July 2009

Acquired activated protein C resistance is associated with IgG antibodies to protein S in patients with systemic lupus erythematosus.

Authors:
Junzo Nojima Yoshinori Iwatani Kiyoshi Ichihara Hidehiro Tsuneoka Toshizo Ishikawa Masashi Yanagihara Toru Takano Yoh Hidaka

Thromb Res 2009 May 7;124(1):127-31. Epub 2009 Jan 7.

Department of Laboratory Science, Faculty of Health Science, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, Japan.

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http://www.clinchem.org/content/51/3/545.full.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S004938480800538
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http://dx.doi.org/10.1016/j.thromres.2008.11.006DOI Listing
May 2009

Increases of the Th1/Th2 cell ratio in severe Hashimoto's disease and in the proportion of Th17 cells in intractable Graves' disease.

Authors:
Takashi Nanba Mikio Watanabe Naoya Inoue Yoshinori Iwatani

Thyroid 2009 May;19(5):495-501

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Yamadaoka 1-7, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/thy.2008.0423DOI Listing
May 2009

Clinical utility and characteristics of nine anti-HCV antibody screening reagents used in Japan.

Authors:
Mifumi Kita Matsuo Deguchi Masanori Kagita Nori Yoshioka Eiji Kobayashi Mikio Watanabe Seishi Asari Kiyoharu Yamanaka Yoshinori Iwatani

Clin Lab 2009 ;55(1-2):9-22

Department of Clinical Laboratory, Otemae Hospital, Osaka, Japan.

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April 2009

In vitro antifungal combination effects of micafungin with fluconazole, voriconazole, amphotericin B, and flucytosine against clinical isolates of Candida species.

Authors:
Isao Nishi Atsuko Sunada Masahiro Toyokawa Seishi Asari Yoshinori Iwatani

J Infect Chemother 2009 Feb 12;15(1):1-5. Epub 2009 Mar 12.

Laboratory for Clinical Investigation, Osaka University Hospital, 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1007/s10156-008-0653-9DOI Listing
February 2009

[Analysis of the causal relations between serum ferritin elevation and latent pathologic factors by structural equation modeling].

Authors:
Hachiro Yamanishi Masaki Hotta Sadao Hayashi Yoh Hidaka Yoshinori Iwatani

Rinsho Byori 2009 Jan;57(1):17-23

Division of Laboratory for Clinical Investigation, Department of Medical Technology, Osaka University Hospital, Suita 565-0871, Japan.

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January 2009

[The medical technologist as a key professional in medical care in the 21st century].

Authors:
Yoshinori Iwatani

Rinsho Byori 2008 Oct;56(10):915-23

Department of Biomedical Informatics, Area of Medical Technology and Science, Division of Health Sciences, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.

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October 2008

Decrease of intrathyroidal CD161+Valpha24+Vbeta11+ NKT cells in Graves' disease.

Authors:
Mikio Watanabe Yukiyo Nakamura Fumio Matsuzuka Yuuki Takamura Akira Miyauchi Yoshinori Iwatani

Endocr J 2008 Mar 4;55(1):199-203. Epub 2008 Feb 4.

Department of Biomedical Informatics, Division of Health Science, Osaka University Graduate School of Medicine, Suita, Japan.

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http://dx.doi.org/10.1507/endocrj.k07e-006DOI Listing
March 2008

Evaluation of a chemiluminescent microparticle immunoassay for determination of Treponema pallidum antibodies.

Authors:
Nori Yoshioka Matsuo Deguchi Masanori Kagita Mifumi Kita Mikio Watanabe Seishi Asari Yoshinori Iwatani

Clin Lab 2007 ;53(9-12):597-603

The Laboratory for Clinical Investigation, Osaka University Hospital, Suita, Japan.

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March 2008

The -590CC genotype in the IL4 gene as a strong predictive factor for the development of hypothyroidism in Hashimoto disease.

Authors:
Takashi Nanba Mikio Watanabe Takashi Akamizu Yoshinori Iwatani

Clin Chem 2008 Mar;54(3):621-3

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http://dx.doi.org/10.1373/clinchem.2007.099739DOI Listing
March 2008

Tissue factor expression on monocytes induced by anti-phospholipid antibodies as a strong risk factor for thromboembolic complications in SLE patients.

Authors:
Junzo Nojima Yumiko Masuda Yoshinori Iwatani Etsuji Suehisa Yoshiaki Futsukaichi Hirohiko Kuratsune Yasuyoshi Watanabe Toru Takano Yoh Hidaka Yuzuru Kanakura

Biochem Biophys Res Commun 2008 Jan 5;365(1):195-200. Epub 2007 Nov 5.

Laboratory for Clinical Investigation, Osaka University Hospital, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2007.10.173DOI Listing
January 2008

Determination of leukocyte counts in cerebrospinal fluid with a disposable plastic hemocytometer.

Authors:
Hachiro Yamanishi Nobuko Imai Etsuji Suehisa Yuzuru Kanakura Yoshinori Iwatani

J Clin Lab Anal 2007 ;21(5):282-5

Laboratory for Clinical Investigation, Osaka University Hospital, Osaka, Japan.

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http://doi.wiley.com/10.1002/jcla.20184
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http://dx.doi.org/10.1002/jcla.20184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649038PMC
December 2007

Ratio of serum IgG3 to total IgG concentration and goiter size are independent factors in intractability of Graves' disease.

Authors:
Tomoko Santoh Mikio Watanabe Shoko Kuroda Daishi Ueda Yoshinori Iwatani

Endocr J 2007 Dec 12;54(6):887-94. Epub 2007 Nov 12.

Department of Biomedical Informatics, Division of Health Science, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1507/endocrj.k07-005DOI Listing
December 2007

[Peritoneal lavage diagnosis with TRC (transcription reverse transcription concerted reaction) system for prediction of peritoneal recurrence in gastric cancer].

Authors:
Hiroyuki Hanada Yoshiyuki Fujiwara Itsuroh Sohma Yurika Nakamura Keiko Takeoka Yoshinori Iwatani Yoh Hidaka

Rinsho Byori 2007 Nov;55(11):1002-7

Division of Laboratory for Clinical Investigation, Department of Medical Technology, Osaka University Hospital, Suita.

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November 2007

Characteristic changes in platelet-large cell ratio, lactate dehydrogenase and C-reactive protein in thrombocytosis-related diseases.

Authors:
Osamu Kabutomori Yuzuru Kanakura Yoshinori Iwatani

Acta Haematol 2007 10;118(2):84-7. Epub 2007 Jul 10.

Central Laboratory for Clinical Investigation, Osaka University Hospital, Suita, Osaka, Japan.

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http://dx.doi.org/10.1159/000105167DOI Listing
October 2007

Genetic association of a polymorphism of the cAMP-responsive element binding protein-binding protein with steroid-induced osteonecrosis after kidney transplantation.

Authors:
Kyoko Tamura Shigeo Nakajima Yoshio Hirota Kenji A Takahashi Mikihiro Fujioka Toshikazu Kubo Yoshinori Iwatani Keiichi Ozono

J Bone Miner Metab 2007 25;25(5):320-5. Epub 2007 Aug 25.

Department of Pediatrics, Osaka University Graduate School of Medicine, 2-2-D5 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1007/s00774-007-0770-zDOI Listing
October 2007

Evaluation of a model of latent pathologic factors in relation to serum ferritin elevation.

Authors:
Hachiro Yamanishi Shigeki Kimura Nobuaki Hata Shigeru Iyama Yuzuru Kanakura Yoshinori Iwatani

Clin Biochem 2007 Mar 5;40(5-6):359-64. Epub 2007 Jan 5.

Laboratory for Clinical Investigation, Osaka University Hospital, 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.clinbiochem.2006.11.022DOI Listing
March 2007

Apoptosis-induced decrease of intrathyroidal CD4(+)CD25(+) regulatory T cells in autoimmune thyroid diseases.

Authors:
Aiko Nakano Mikio Watanabe Takao Iida Shoko Kuroda Fumio Matsuzuka Akira Miyauchi Yoshinori Iwatani

Thyroid 2007 Jan;17(1):25-31

Division of Biomedical Informatics, Course of Health Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/thy.2006.0231DOI Listing
January 2007

Penicillin susceptibility of non-serotypeable Streptococcus pneumoniae from ophthalmic specimens.

Authors:
Fumiko Kojima Yoshiko Nakagami Koichi Takemori Yoshinori Iwatani Shuji Fujimoto

Microb Drug Resist 2006 ;12(3):199-202

Infectious Diseases Laboratory, Department of Health Sciences, School of Medicine, Kyushu University, Fukuoka, 812-8582, Japan.

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http://dx.doi.org/10.1089/mdr.2006.12.199DOI Listing
November 2006

Insufficient filling of vacuum tubes as a cause of microhemolysis and elevated serum lactate dehydrogenase levels. Use of a data-mining technique in evaluation of questionable laboratory test results.

Authors:
Yoshie Tamechika Yoshinori Iwatani Kaoru Tohyama Kiyoshi Ichihara

Clin Chem Lab Med 2006 ;44(5):657-61

Department of Clinical Laboratory, Kawasaki Medical School Hospital, Kurashiki, Japan.

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http://dx.doi.org/10.1515/CCLM.2006.109DOI Listing
August 2006

Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-gamma gene.

Authors:
Chisato Ito Mikio Watanabe Noriko Okuda Chikami Watanabe Yoshinori Iwatani

Endocr J 2006 Aug 5;53(4):473-8. Epub 2006 Jul 5.

Department of Biomedical Informatics, Division of Health Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1507/endocrj.k06-015DOI Listing
August 2006

Urine flow cytometer quantification of leukocytes in samples containing a large proportion of lymphocytes.

Authors:
Hachiro Yamanishi Nobuko Imai Toshinari Ohmine Miho Nishiyama Etsuji Suehisa Yuzuru Kanakura Yoshinori Iwatani

Clin Biochem 2006 Aug 26;39(8):857-9. Epub 2006 May 26.

Laboratory for Clinical Investigation, Osaka University Hospital, 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.clinbiochem.2006.05.003DOI Listing
August 2006

The presence of anti-phosphatidylserine/prothrombin antibodies as risk factor for both arterial and venous thrombosis in patients with systemic lupus erythematosus.

Authors:
Junzo Nojima Yoshinori Iwatani Etsuji Suehisa Hirohiko Kuratsune Yuzuru Kanakura

Haematologica 2006 May 19;91(5):699-702. Epub 2006 Apr 19.

Laboratory for Clinical Investigation, Osaka University Hospital, Suita, Osaka 565-0871, Japan.

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May 2006

[T3 toxicosis].

Authors:
Yoshinori Iwatani

Nihon Rinsho 2006 May;Suppl 1:276-8

Department of Biomedical Informatics, Division of Health Science, Osaka University Graduate School of Medicine.

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May 2006

A useful new classification of dysmorphic urinary erythrocytes.

Authors:
Daisuke Nagahama Kenichi Yoshiko Mikio Watanabe Yoshiki Morita Yoshinori Iwatani Seiichi Matsuo

Clin Exp Nephrol 2005 Dec;9(4):304-309

Division of Internal Medicine, Nagoya University Graduate School of Medicine, Aichi, Japan.

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http://dx.doi.org/10.1007/s10157-005-0380-9DOI Listing
December 2005

Multiple SNPs in intron 7 of thyrotropin receptor are associated with Graves' disease.

Authors:
Hitomi Hiratani Donald W Bowden Satoshi Ikegami Senji Shirasawa Akira Shimizu Yoshinori Iwatani Takashi Akamizu

J Clin Endocrinol Metab 2005 May 1;90(5):2898-903. Epub 2005 Mar 1.

Department of Experimental Therapeutics, Translational Research Center, Kyoto University Hospital, Kyoto University School of Medicine, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1210/jc.2004-2148DOI Listing
May 2005

Acquired activated protein C resistance associated with IgG antibodies against beta2-glycoprotein I and prothrombin as a strong risk factor for venous thromboembolism.

Authors:
Junzo Nojima Hirohiko Kuratsune Etsuji Suehisa Yoshinori Iwatani Yuzuru Kanakura

Clin Chem 2005 Mar 6;51(3):545-52. Epub 2005 Jan 6.

Laboratory for Clinical Investigation, Osaka University Hospital, Osaka, Japan.

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http://dx.doi.org/10.1373/clinchem.2004.043414DOI Listing
March 2005

Inflammation markers and liver dysfunction.

Authors:
Osamu Kabutomori Yuzuru Kanakura Yoshinori Iwatani

Ann Hematol 2005 Feb 29;84(2):136. Epub 2004 Oct 29.

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http://dx.doi.org/10.1007/s00277-004-0967-3DOI Listing
February 2005

[Evaluation of seven immunological assay reagents for hepatitis B virus surface antigen (HBsAg) in the sensitivity and the detection of HBsAg mutants].

Authors:
Matsuo Deguchi Masanori Kagita Seishi Asari Yoshinori Iwatani Takahiko Tuchida Kazushige Iinuma Mark Sanborn

Kansenshogaku Zasshi 2005 Feb;79(2):138-42

Laboratory for Clinical Investigation, Osaka University Hospital.

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http://dx.doi.org/10.11150/kansenshogakuzasshi1970.79.138DOI Listing
February 2005

Intrathyroidal CD4+ T lymphocytes express high levels of Fas and CD4+ CD8+ macrophages/dendritic cells express Fas ligand in autoimmune thyroid disease.

Authors:
Yukiyo Nakamura Mikio Watanabe Fumio Matsuzuka Hayato Maruoka Akira Miyauchi Yoshinori Iwatani

Thyroid 2004 Oct;14(10):819-24

Division of Biomedical Informatics, Course of Health Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/thy.2004.14.819DOI Listing
October 2004

[Current topics on immunological laboratory tests-thyroid diseases].

Authors:
Yoshinori Iwatani

Rinsho Byori 2004 Sep;52(9):751-8

Osaka University Graduate School of Medicine, Course of Health Science, Division of Biomedical Informatics, Suita.

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September 2004

Increased intensities of fas expression on peripheral T-cell subsets in severe autoimmune thyroid disease.

Authors:
Hayato Maruoka Mikio Watanabe Fumio Matsuzuka Tadashi Takimoto Akira Miyauchi Yoshinori Iwatani

Thyroid 2004 Jun;14(6):417-23

Division of Biomedical Informatics, Course of Health Sciences, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/105072504323150723DOI Listing
June 2004

Strong correlation between the prevalence of cerebral infarction and the presence of anti-cardiolipin/beta2-glycoprotein I and anti-phosphatidylserine/prothrombin antibodies--Co-existence of these antibodies enhances ADP-induced platelet activation in vitro.

Authors:
Junzo Nojima Hirohiko Kuratsune Etsuji Suehisa Teruo Kitani Yoshinori Iwatani Yuzuru Kanakura

Thromb Haemost 2004 May;91(5):967-76

Laboratory for Clinical Investigation, Osaka University Hospital, 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1160/TH03-10-0608DOI Listing
May 2004

Increase of serum interleukin-10 in intractable Graves' disease.

Authors:
Keiko Takeoka Mikio Watanabe Fumio Matsuzuka Akira Miyauchi Yoshinori Iwatani

Thyroid 2004 Mar;14(3):201-5

Division of Biomedical Informatics, Course of Health Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/105072504773297876DOI Listing
March 2004

A new quality control method based on a moving average of "latent reference values" selected from patients' daily test results.

Authors:
Sadao Hayashi Kiyoshi Ichihara Yuzuru Kanakura Yoshinori Iwatani

Rinsho Byori 2004 Mar;52(3):204-11

Laboratory for Clinical Investigation, Osaka University Hospital, Division of Biomedical Informatics, Osaka University, Graduate School of Medicine, Suita 565-0871.

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March 2004

Quantitation of hepatitis B surface antigen by an automated chemiluminescent microparticle immunoassay.

Authors:
Matsuo Deguchi Naoko Yamashita Masanori Kagita Seishi Asari Yoshinori Iwatani Takahiko Tsuchida Kazushige Iinuma Isa K Mushahwar

J Virol Methods 2004 Feb;115(2):217-22

The Laboratory for Clinical Investigation, Osaka University Hospital, 2-15 Yamadaoka, Suita-shi, 565-0871, Osaka, Japan.

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http://dx.doi.org/10.1016/j.jviromet.2003.10.002DOI Listing
February 2004

Physiological changes of Fas expression in peripheral lymphocyte subsets during the menstrual cycle.

Authors:
Rie Shinoda Mikio Watanabe Yukiyo Nakamura Hayato Maruoka Yukari Kimura Yoshinori Iwatani

J Reprod Immunol 2003 Dec;60(2):159-68

Department of Clinical Laboratory Science, School of Allied Health Science, Osaka University, 1-7 Yamada-oka, Suita, 565-0871 Osaka, Japan.

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http://dx.doi.org/10.1016/s0165-0378(03)00107-4DOI Listing
December 2003

[Clinical evaluation of polymerase chain reaction (PCR) method for the detection of hepatitis B virus (HBV)-DNA].

Authors:
Kazuko Tahara Matsuo Deguchi Masanori Kagita Takashi Nakano Kaori Ichigo Yuko Sasahara Seishi Asari Yuzuru Kanakura Yoshinori Iwatani

Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi 2003 ;13(2):121-8

Laboratory for Clinical Investigation, Osaka University Hospital, 2-15, Yamadaoka, Suita-shi, Osaka 565-0871, Japan.

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October 2003

Marked decreases of total and immature reticulocytes in myelodysplastic syndrome among patients with pancytopenia.

Authors:
Osamu Kabutomori Yuzuru Kanakura Yoshinori Iwatani

Acta Haematol 2003 ;109(4):212-3

Central Laboratory for Clinical Investigation, Osaka University Hospital, Suita, Japan.

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http://dx.doi.org/10.1159/000070975DOI Listing
August 2003

Evaluation of MicroScan ESBL confirmation panel for Enterobacteriaceae-producing, extended-spectrum beta-lactamases isolated in Japan.

Authors:
Masaru Komatsu Masanori Aihara Kouichi Shimakawa Mizuho Iwasaki Yoko Nagasaka Saori Fukuda Shuji Matsuo Yoshinori Iwatani

Diagn Microbiol Infect Dis 2003 Jun;46(2):125-30

Division of Clinical Microbiology, Department of Clinical Pathology, Tenri Hospital, Nara, Japan.

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http://dx.doi.org/10.1016/s0732-8893(03)00041-5DOI Listing
June 2003