Publications by authors named "Yoshinobu Ichimura"

35Publications

Activation of p62/SQSTM1-Keap1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in Cancer.

Front Oncol 2018 7;8:210. Epub 2018 Jun 7.

Department of Biochemistry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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https://www.frontiersin.org/article/10.3389/fonc.2018.00210/
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http://dx.doi.org/10.3389/fonc.2018.00210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999793PMC
June 2018

Negative Regulation of the Keap1-Nrf2 Pathway by a p62/Sqstm1 Splicing Variant.

Mol Cell Biol 2018 04 15;38(7). Epub 2018 Mar 15.

Department of Biochemistry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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http://dx.doi.org/10.1128/MCB.00642-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854834PMC
April 2018

Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor.

Bioorg Med Chem Lett 2017 11 6;27(22):5006-5009. Epub 2017 Oct 6.

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.10.008DOI Listing
November 2017

Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity.

Bioorg Med Chem Lett 2016 12 27;26(24):5956-5959. Epub 2016 Oct 27.

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.10.083DOI Listing
December 2016

p62/SQSTM1 functions as a signaling hub and an autophagy adaptor.

FEBS J 2015 Dec 16;282(24):4672-8. Epub 2015 Oct 16.

Department of Biochemistry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1111/febs.13540DOI Listing
December 2015

LC3B is indispensable for selective autophagy of p62 but not basal autophagy.

Biochem Biophys Res Commun 2014 Mar 28;446(1):309-15. Epub 2014 Feb 28.

Protein Metabolism Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.02.093DOI Listing
March 2014

[Involvement of ubiquitin system in mammalian autophagy].

Seikagaku 2012 Jun;84(6):472-8

Protein Metabolism Project, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo 156-8506, Japan.

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June 2012

p62/SQSTM1/A170: physiology and pathology.

Pharmacol Res 2012 Dec 25;66(6):457-62. Epub 2012 Jul 25.

Protein Metabolism Project, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo 156-8506, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S10436618120014
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http://dx.doi.org/10.1016/j.phrs.2012.07.004DOI Listing
December 2012

Pathophysiological role of autophagy: lesson from autophagy-deficient mouse models.

Exp Anim 2011 ;60(4):329-45

Protein Metabolism Project, Tokyo Metropolitan Institute of Medical ScienceSetagaya-ku, Tokyo 156-8501, Japan.

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http://dx.doi.org/10.1538/expanim.60.329DOI Listing
November 2011

Crucial role for autophagy in degranulation of mast cells.

J Allergy Clin Immunol 2011 May 18;127(5):1267-76.e6. Epub 2011 Feb 18.

Atopy (Allergy) Research Center, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jaci.2010.12.1078DOI Listing
May 2011

Selective degradation of p62 by autophagy.

Semin Immunopathol 2010 Dec 3;32(4):431-6. Epub 2010 Sep 3.

Protein Metabolism Project, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo 156-8506, Japan.

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http://dx.doi.org/10.1007/s00281-010-0220-1DOI Listing
December 2010

Selective autophagy regulates various cellular functions.

Genes Cells 2010 Sep 28;15(9):923-33. Epub 2010 Jul 28.

Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Japan.

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http://doi.wiley.com/10.1111/j.1365-2443.2010.01433.x
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http://dx.doi.org/10.1111/j.1365-2443.2010.01433.xDOI Listing
September 2010

Physiological significance of selective degradation of p62 by autophagy.

FEBS Lett 2010 Apr 12;584(7):1374-8. Epub 2010 Feb 12.

Laboratory of Frontier Science, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.febslet.2010.02.017DOI Listing
April 2010

Anti-proliferative and apoptosis-inducible activity of Sarcodonin G from Sarcodon scabrosus in HeLa cells.

Int J Oncol 2009 Jan;34(1):201-7

Department of Medicinal Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang 050017, P.R. China.

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January 2009

[Neuronal autophagy, its defects and neurodegenerative diseases].

Tanpakushitsu Kakusan Koso 2008 Dec;53(16 Suppl):2175-81

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December 2008

Selective turnover of p62/A170/SQSTM1 by autophagy.

Autophagy 2008 Nov 20;4(8):1063-6. Epub 2008 Nov 20.

Department of Biochemistry, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan.

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http://dx.doi.org/10.4161/auto.6826DOI Listing
November 2008

Structural basis for sorting mechanism of p62 in selective autophagy.

J Biol Chem 2008 Aug 4;283(33):22847-57. Epub 2008 Jun 4.

Department of Biochemistry, Juntendo University School of Medicine, Tokyo 113-8421.

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http://dx.doi.org/10.1074/jbc.M802182200DOI Listing
August 2008

Annexin II, a novel HSP27-interacted protein, is involved in resistance to UVC-induced cell death in human APr-1 cells.

Photochem Photobiol 2008 Nov-Dec;84(6):1455-61. Epub 2008 May 20.

Department of Environmental Biochemistry, Graduate School of Medicine, Chiba University, Chiba, Japan.

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http://doi.wiley.com/10.1111/j.1751-1097.2008.00365.x
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http://dx.doi.org/10.1111/j.1751-1097.2008.00365.xDOI Listing
February 2009

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.

J Biol Chem 2007 Dec 6;282(52):37298-302. Epub 2007 Nov 6.

Division of Molecular Cell Biology, National Institute for Basic Biology, Myodaiji, Okazaki, Japan.

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http://dx.doi.org/10.1074/jbc.C700195200DOI Listing
December 2007

Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion.

Cell 2007 Jul;130(1):165-78

Department of Cell Biology, National Institute for Basic Biology, Okazaki 444-8585, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00928674070065
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http://dx.doi.org/10.1016/j.cell.2007.05.021DOI Listing
July 2007

The crystal structure of Atg3, an autophagy-related ubiquitin carrier protein (E2) enzyme that mediates Atg8 lipidation.

J Biol Chem 2007 Mar 16;282(11):8036-43. Epub 2007 Jan 16.

Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Hokkaido University, N-12, W-6, Kita-ku, Sapporo 060-0812, Japan.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M611473200
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http://dx.doi.org/10.1074/jbc.M611473200DOI Listing
March 2007

Crystallization and preliminary X-ray analysis of Atg3.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 Oct 30;62(Pt 10):1016-7. Epub 2006 Sep 30.

Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Hokkaido University, N-12, W-6, Kita-ku, Sapporo 060-0812, Japan.

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http://scripts.iucr.org/cgi-bin/paper?S1744309106036098
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http://dx.doi.org/10.1107/S1744309106036098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225171PMC
October 2006

Two newly identified sites in the ubiquitin-like protein Atg8 are essential for autophagy.

EMBO Rep 2006 Jun 5;7(6):635-42. Epub 2006 May 5.

Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1038/sj.embor.7400698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479593PMC
June 2006

In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy.

J Biol Chem 2004 Sep 23;279(39):40584-92. Epub 2004 Jul 23.

Department of Cell Biology, National Institute for Basic Biology, 38 Nishigonaka, Myodaiji, Okazaki, 444-8585, Japan.

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http://dx.doi.org/10.1074/jbc.M405860200DOI Listing
September 2004