Publications

Degradation of human Lipin-1 by BTRC E3 ubiquitin ligase.
Biochem Biophys Res Commun 2017 Jun 5;488(1):159-164. Epub 2017 May 5.
Laboratory of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address:

Angubindin-1, a novel paracellular absorption enhancer acting at the tricellular tight junction.
J Control Release 2017 May 18;260:1-11. Epub 2017 May 18.
Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan. Electronic address:

Establishment of a reference material for standardization of the anti-complementary activity test in intravenous immunoglobulin products used in Japan: A collaborative study.
Biologicals 2017 Mar 3;46:68-73. Epub 2017 Feb 3.
Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Musashimurayama, Tokyo 208-0011, Japan. Electronic address:

Adenovirus vector-based incorporation of a photo-cross-linkable amino acid into proteins in human primary cells and cancerous cell lines.
Sci Rep 2016 Nov 11;6:36946. Epub 2016 Nov 11.
Laboratory of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.



Generation and characterization of a human-mouse chimeric antibody against the extracellular domain of claudin-1 for cancer therapy using a mouse model.
Biochem Biophys Res Commun 2016 Aug 8;477(1):91-5. Epub 2016 Jun 8.
Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan. Electronic address:


Expression of the Robo4 receptor in endothelial cells is regulated by two AP-1 protein complexes.
Biochem Biophys Res Commun 2015 Nov 14;467(4):987-91. Epub 2015 Oct 14.
Center for Vascular Biology Research and Division of Molecular and Vascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Endothelial cell-specific expression of roundabout 4 is regulated by differential DNA methylation of the proximal promoter.
Arterioscler Thromb Vasc Biol 2014 Jul 22;34(7):1531-8. Epub 2014 May 22.
From the Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan (Y.O., N.F., T.T., Y.N., K.S., Y.K., H.N., A.S., M.S., J.Z., K.I., N.H., M.K., Y.M., S.N., T.D.); Center for Vascular Biology Research and Division of Molecular and Vascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (L.Y., W.C.A.); Department of Pathology, Center for Excellence in Vascular Biology, Harvard Medical School, Boston, MA (A.S.T., G.G.-C.); Department of Material Sciences, Massachusetts Institute of Technology, Boston (A.S.T.); and Stem Cell Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan (K.K.).


An induced pluripotent stem cell-mediated and integration-free factor VIII expression system.
Biochem Biophys Res Commun 2013 Feb 3;431(2):336-41. Epub 2013 Jan 3.
Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Tottori, Japan.

Highly regio- and stereoselective synthesis of multialkylated olefins through carbozirconation of alkynylboronates and sequential Negishi and Suzuki-Miyaura coupling reactions.
Angew Chem Int Ed Engl 2011 Sep 9;50(37):8660-4. Epub 2011 Aug 9.
Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushimanaka, Kita-ku, Okayama 700-8530, Japan.


Differential roles for ETS, CREB, and EGR binding sites in mediating VEGF receptor 1 expression in vivo.
Blood 2009 Dec 12;114(27):5557-66. Epub 2009 Oct 12.
The Center for Vascular Biology Research and Division of Molecular and Vascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.


Elevated levels of placental growth factor represent an adaptive host response in sepsis.
J Exp Med 2008 Oct 13;205(11):2623-31. Epub 2008 Oct 13.
The Center for Vascular Biology Research and Division of Molecular and Vascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo.
Blood 2008 Sep 2;112(6):2336-9. Epub 2008 Jun 2.
Center for Vascular Biology Research and Division of Molecular and Vascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

Ligand-independent assembly of purified soluble magic roundabout (Robo4), a tumor-specific endothelial marker.
Protein Expr Purif 2008 Sep 21;61(1):78-82. Epub 2008 May 21.
Department of Biotechnology and Therapeutics, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.


A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium.
Circ Res 2007 Jun 10;100(12):1712-22. Epub 2007 May 10.
Center for Vascular Biology Research and Division of Molecular and Vascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression.
J Biol Chem 2006 Nov 15;281(46):35544-53. Epub 2006 Sep 15.
Center for Vascular Biology Research, Department of Medicine, the Division of Molecular, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA.

Medium (DMEM/F12)-containing chitosan hydrogel as adhesive and dressing in autologous skin grafts and accelerator in the healing process.
J Biomed Mater Res B Appl Biomater 2006 Oct;79(1):129-36
Department of Traumatology and Critical Care Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.


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