Yosef Shiloh

Yosef Shiloh

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Yosef Shiloh

Yosef Shiloh

Publications by authors named "Yosef Shiloh"

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83Publications

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The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair.

Mol Cell 2018 Mar;69(5):866-878.e7

The David and Inez Myers Laboratory for Cancer Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

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March 2018

Monitoring the ATM-Mediated DNA Damage Response in the Cerebellum Using Organotypic Cultures.

Methods Mol Biol 2017 ;1599:419-430

The David and Inez Myers Laboratory for Cancer Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.

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February 2018

Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair.

Nucleic Acids Res 2018 Jan;46(2):730-747

Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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January 2018

Genome instability: Linking ageing and brain degeneration.

Mech Ageing Dev 2017 01 31;161(Pt A):4-18. Epub 2016 Mar 31.

Department of Human Molecular genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address:

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January 2017

Ataxia-telangiectasia (A-T): An emerging dimension of premature ageing.

Ageing Res Rev 2017 Jan 12;33:76-88. Epub 2016 May 12.

Division of Pediatric Allergy and Immunology, The Johns Hopkins Medical Institutions, 600 N. Wolfe Street, Baltimore, MD 21287, USA.

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January 2017

Systemic DNA damage responses in aging and diseases.

Semin Cancer Biol 2016 06 7;37-38:26-35. Epub 2016 Jan 7.

Institute for Genome Stability in Ageing and Disease, Cologne Cluster of Excellence in Cellular Stress Responses in Aging-associated Diseases (CECAD) Research Center, Center for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany. Electronic address:

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June 2016

The COP9 signalosome is vital for timely repair of DNA double-strand breaks.

Nucleic Acids Res 2015 May 8;43(9):4517-30. Epub 2015 Apr 8.

The David and Inez Myers Laboratory for Cancer Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, George S. Wise Faculty of Life sciences, Tel Aviv University, Tel Aviv, 69978 Israel

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May 2015

ATM: expanding roles as a chief guardian of genome stability.

Authors:
Yosef Shiloh

Exp Cell Res 2014 Nov 8;329(1):154-61. Epub 2014 Sep 8.

The David and Inez Myers Laboratory for Cancer Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address:

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November 2014

Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation.

Sci Signal 2014 May 13;7(325):rs3. Epub 2014 May 13.

The David and Inez Myers Laboratory for Cancer Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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May 2014

Studying the cerebellar DNA damage response in the tissue culture dish.

Mech Ageing Dev 2013 Oct 9;134(10):496-505. Epub 2013 Apr 9.

The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Tel Aviv 69978, Israel.

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October 2013

DNA damage response, bioenergetics, and neurological disease: the challenge of maintaining brain health in an aging human population.

Mech Ageing Dev 2013 Oct 10;134(10):427-33. Epub 2013 May 10.

Center for Healthy Aging, Faculty of Health Sciences, University of Copenhagen, Denmark.

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October 2013

The ATM protein kinase: regulating the cellular response to genotoxic stress, and more.

Nat Rev Mol Cell Biol 2013 Apr 13;14(4):197-210. Epub 2013 Mar 13.

The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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April 2013

The ATM protein kinase: regulating the cellular response to genotoxic stress, and more.

Nat Rev Mol Cell Biol 2013 Apr;14(4):197-210

The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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April 2013

The ATM protein: the importance of being active.

J Cell Biol 2012 Aug;198(3):273-5

The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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August 2012

Malfunctioning DNA damage response (DDR) leads to the degeneration of nigro-striatal pathway in mouse brain.

J Mol Neurosci 2012 Mar 16;46(3):554-68. Epub 2011 Sep 16.

Department of Neurobiology, George S. Wise, Faculty of Life Sciences, Tel Aviv University, Tel Aviv, 69978, Israel.

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March 2012

Matrin 3 binds and stabilizes mRNA.

PLoS One 2011 17;6(8):e23882. Epub 2011 Aug 17.

The David and Inez Myers Laboratory for Cancer Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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February 2012

Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks.

Cell Cycle 2011 Dec 15;10(24):4300-10. Epub 2011 Dec 15.

The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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December 2011

Astrocyte dysfunction associated with cerebellar attrition in a Nijmegen breakage syndrome animal model.

J Mol Neurosci 2011 Oct 29;45(2):202-11. Epub 2011 Jan 29.

Department of Neurobiology, George S. Wise, Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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October 2011

A role for vascular deficiency in retinal pathology in a mouse model of ataxia-telangiectasia.

Am J Pathol 2011 Sep 19;179(3):1533-41. Epub 2011 Jul 19.

Department of Neurobiology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.

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September 2011

RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response.

FEBS Lett 2011 Sep 4;585(18):2795-802. Epub 2011 Aug 4.

The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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September 2011

Transcriptional modulation induced by ionizing radiation: p53 remains a central player.

Mol Oncol 2011 Aug 7;5(4):336-48. Epub 2011 Jul 7.

The David and Inez Myers Laboratory for Genetic Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Room 1022, Tel Aviv 69978, Israel.

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August 2011

ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair.

EMBO Rep 2011 Jul 1;12(7):713-9. Epub 2011 Jul 1.

The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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July 2011

Beyond ATM: the protein kinase landscape of the DNA damage response.

FEBS Lett 2011 Jun 8;585(11):1625-39. Epub 2011 May 8.

Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland.

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June 2011

Investigation of the functional link between ATM and NBS1 in the DNA damage response in the mouse cerebellum.

J Biol Chem 2011 Apr 7;286(17):15361-76. Epub 2011 Feb 7.

Department of Neurobiology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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April 2011

SPIKE: a database of highly curated human signaling pathways.

Nucleic Acids Res 2011 Jan 19;39(Database issue):D793-9. Epub 2010 Nov 19.

Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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January 2011

KAP1 depletion increases PML nuclear body number in concert with ultrastructural changes in chromatin.

Cell Cycle 2011 Jan 15;10(2):308-22. Epub 2011 Jan 15.

Department of Pathology, Dalhousie University, Halifax, NS, Canada.

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January 2011

ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage.

Sci Signal 2010 Dec 7;3(151):rs3. Epub 2010 Dec 7.

David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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December 2010

3rd US-EU workshop: systems level understanding of DNA damage responses.

Mutat Res 2010 Oct 19;692(1-2):53-60. Epub 2010 Aug 19.

University at Albany, SUNY, Rensselaer, New York, NY 12144-3456, USA.

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October 2010

Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response.

Cell Cycle 2010 Apr 15;9(8):1568-76. Epub 2010 Apr 15.

Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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April 2010

Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks.

Proc Natl Acad Sci U S A 2010 Feb 25;107(5):2207-12. Epub 2010 Jan 25.

The Goldyne Savad Institute of Gene Therapy, Magnetic Resonance Imaging/Magnetic Resonance Spectroscopy Laboratory, Hadassah Hebrew University Medical Center, Jerusalem, Israel.

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February 2010

Expander: from expression microarrays to networks and functions.

Nat Protoc 2010 Feb 28;5(2):303-22. Epub 2010 Jan 28.

Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel.

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February 2010

USP10: friend and foe.

Cell 2010 Feb;140(3):308-10

Department of Molecular Cell Biology, Leiden University Medical Center, 2300RC Leiden, The Netherlands.

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February 2010

Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK.

EMBO J 2009 Dec 22;28(23):3667-80. Epub 2009 Oct 22.

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4255, USA.

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December 2009

Simultaneous identification and quantification of proteins by differential (16)O/(18)O labeling and UPLC-MS/MS applied to mouse cerebellar phosphoproteome following irradiation.

Anticancer Res 2009 Dec;29(12):4949-58

Molecular Structure Analysis (W160), German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

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December 2009

FBXO31: a new player in the ever-expanding DNA damage response orchestra.

Authors:
Yosef Shiloh

Sci Signal 2009 Nov 10;2(96):pe73. Epub 2009 Nov 10.

The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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November 2009

Analysis of the relationships between ATM and the Rad54 paralogs involved in homologous recombination repair.

DNA Repair (Amst) 2009 Feb 30;8(2):253-61. Epub 2008 Dec 30.

Department of Neurobiology, George S. Wise, Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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February 2009

Citrate boosts the performance of phosphopeptide analysis by UPLC-ESI-MS/MS.

J Proteome Res 2009 Jan;8(1):418-24

Molecular Structure Analysis, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

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January 2009

Activation of ATM depends on chromatin interactions occurring before induction of DNA damage.

Nat Cell Biol 2009 Jan 14;11(1):92-6. Epub 2008 Dec 14.

Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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January 2009

WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks.

Mol Biol Cell 2008 Sep 2;19(9):3923-33. Epub 2008 Jul 2.

Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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September 2008

The neurological phenotype of ataxia-telangiectasia: solving a persistent puzzle.

DNA Repair (Amst) 2008 Jul 5;7(7):1028-38. Epub 2008 May 5.

Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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July 2008

The role of the DNA damage response in neuronal development, organization and maintenance.

DNA Repair (Amst) 2008 Jul 23;7(7):1010-27. Epub 2008 May 23.

Department of Neurobiology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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July 2008

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin.

Mol Cell 2008 Jul;31(2):167-77

Genome Damage and Stability Centre, University of Sussex, East Sussex BN1 9RQ, UK.

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July 2008

SPIKE--a database, visualization and analysis tool of cellular signaling pathways.

BMC Bioinformatics 2008 Feb 20;9:110. Epub 2008 Feb 20.

The David and Inez Myers Laboratory for Genetic Research, Department of Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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February 2008

MRI evidence of white matter damage in a mouse model of Nijmegen breakage syndrome.

Exp Neurol 2008 Jan 2;209(1):181-91. Epub 2007 Oct 2.

Department of Neurobiochemistry, George S Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.

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January 2008

Functional genomic delineation of TLR-induced transcriptional networks.

BMC Genomics 2007 Oct 29;8:394. Epub 2007 Oct 29.

The David and Inez Myers Laboratory for Genetic Research, Department of Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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October 2007

Ataxia-telangiectasia: mild neurological presentation despite null ATM mutation and severe cellular phenotype.

Am J Med Genet A 2007 Aug;143A(16):1827-34

The David and Inez Myers Laboratory for Genetic Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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August 2007

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Science 2007 May;316(5828):1160-6

Department of Genetics and Center for Genetics and Genomics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

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May 2007

Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.

J Biol Chem 2007 Mar 21;282(9):6582-7. Epub 2006 Dec 21.

Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA.

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March 2007

Programs for cell death: apoptosis is only one way to go.

Cell Cycle 2007 Mar 7;6(6):686-95. Epub 2007 Mar 7.

The David and Inez Myers Laboratory for Genetic Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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March 2007

ATM-mediated response to DNA double strand breaks in human neurons derived from stem cells.

DNA Repair (Amst) 2007 Jan 18;6(1):128-34. Epub 2006 Dec 18.

David and Inez Myers Laboratory for Genetic Research, Department of Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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January 2007

Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage.

Mol Cell Biol 2006 Sep;26(18):6819-31

Department of Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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September 2006

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway.

Nat Cell Biol 2006 Aug 23;8(8):870-6. Epub 2006 Jul 23.

The David and Inez Myers Laboratory for Genetic Research, Department of Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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August 2006

The ATM-mediated DNA-damage response: taking shape.

Authors:
Yosef Shiloh

Trends Biochem Sci 2006 Jul 13;31(7):402-10. Epub 2006 Jun 13.

The David and Inez Myers Laboratory for Genetic Research, Department of Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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July 2006

Condensin I recruitment and uneven chromatin condensation precede mitotic cell death in response to DNA damage.

J Cell Biol 2006 Jul;174(2):195-206

The David and Inez Myers Laboratory for Genetic Research, Department of Molecular Genetics and Biochemistry, and Interdepartmental Core Facility, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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July 2006

Analysis of the ataxia telangiectasia mutated-mediated DNA damage response in murine cerebellar neurons.

J Neurosci 2006 Jul;26(29):7767-74

Department of Neurobiochemistry, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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July 2006

Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells.

J Biol Chem 2006 Jun 20;281(25):17482-91. Epub 2006 Apr 20.

The David and Inez Myers Laboratory for Genetic Research, Department of Molecular Genetics and Biochemistry, Tel Aviv University, Tel Aviv 69978, Israel.

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June 2006

Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis.

Genome Biol 2005 13;6(5):R43. Epub 2005 Apr 13.

The David and Inez Myers Laboratory for Genetic Research, Department of Human Genetics, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.

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May 2006

Deciphering transcriptional regulatory elements that encode specific cell cycle phasing by comparative genomics analysis.

Cell Cycle 2005 Dec 13;4(12):1788-97. Epub 2005 Dec 13.

School of Computer Science, Tel Aviv University, Tel Aviv, Israel.

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December 2005

ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation.

Cell Cycle 2005 Sep 29;4(9):1166-70. Epub 2005 Sep 29.

Department of Molecular and Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.

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September 2005

EXPANDER--an integrative program suite for microarray data analysis.

BMC Bioinformatics 2005 Sep 21;6:232. Epub 2005 Sep 21.

School of Computer Science, Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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September 2005

ATM-dependent phosphorylation of ATF2 is required for the DNA damage response.

Mol Cell 2005 May;18(5):577-87

Signal Transduction Program, The Burnham Institute, La Jolla, California 92037, USA.

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May 2005

Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.

Proc Natl Acad Sci U S A 2005 Apr 23;102(14):5056-61. Epub 2005 Mar 23.

The David and Inez Myers Laboratory for Genetic Research, Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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April 2005

Maintaining integrity.

Nat Cell Biol 2004 Oct;6(10):923-8

The David and Inez Myers Laboratory for Genetic Research, Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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October 2004

In silico identification of transcriptional regulators associated with c-Myc.

Nucleic Acids Res 2004 23;32(17):4955-61. Epub 2004 Sep 23.

The David and Inez Myers Laboratory for Genetic Research, Department of Human Genetics, Sackler School of Medicine, Tel Aviv University, Israel.

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September 2004

In search of drug treatment for genetic defects in the DNA damage response: the example of ataxia-telangiectasia.

Semin Cancer Biol 2004 Aug;14(4):295-305

Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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August 2004

ATM: ready, set, go.

Authors:
Yosef Shiloh

Cell Cycle 2003 Mar-Apr;2(2):116-7

The Dovid and Inez Myers Laboratory lor Genetic Research, Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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April 2004

PIVOT: protein interacions visualizatiOn tool.

Bioinformatics 2004 Feb 22;20(3):424-5. Epub 2004 Jan 22.

Department of Human Genetics, Faculty of Medicine, Tel Aviv University, Israel.

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February 2004

Requirement of the MRN complex for ATM activation by DNA damage.

EMBO J 2003 Oct;22(20):5612-21

The David and Inez Myers Laboratory for Genetic Research, Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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October 2003

Genome-wide in silico identification of transcriptional regulators controlling the cell cycle in human cells.

Genome Res 2003 May;13(5):773-80

The David and Inez Myers Laboratory for Genetic Research, Department of Human Genetics, Sackler School of Medicine, and School of Computer Science, Tel Aviv University, Tel Aviv 69978, Israel.

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May 2003

ATM and related protein kinases: safeguarding genome integrity.

Authors:
Yosef Shiloh

Nat Rev Cancer 2003 Mar;3(3):155-68

The David and Inez Myers Laboratory for Genetic Research, Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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March 2003

Contribution of the Atm protein to maintaining cellular homeostasis evidenced by continuous activation of the AP-1 pathway in Atm-deficient brains.

J Biol Chem 2003 Feb 19;278(9):6741-7. Epub 2002 Dec 19.

Department of Neurobiochemistry, George S. Wise Faculty of Life Sciences, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978 Israel.

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February 2003

Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.

Biochem J 2002 Dec;368(Pt 2):507-16

MRC Protein Phosphorylation Unit, MSI/WTB Complex, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, U.K.

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December 2002

Ubiquitination capabilities in response to neocarzinostatin and H(2)O(2) stress in cell lines from patients with ataxia-telangiectasia.

Oncogene 2002 Jun;21(28):4363-73

JM USDA Human Nutrition Research Center on Aging at Tufts University, Laboratory for Nutrition and Vision Research, 711 Washington Street, Boston, Massachusetts 02111, USA.

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June 2002

Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice.

J Biol Chem 2002 Jan 25;277(1):602-8. Epub 2001 Oct 25.

Department of Neurobiochemistry, George S. Wise Faculty of Life Sciences, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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January 2002

ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage.

Oncogene 2002 Jan;21(5):849-55

The David and Inez Myers Laboratory for Genetic Research, Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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January 2002

ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage.

DNA Repair (Amst) 2002 Jan;1(1):3-25

Department of Neurobiochemistry, George S. Wise Faculty of Life Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.

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January 2002