Yoongho Lim

Yoongho Lim

UNVERIFIED PROFILE

Are you Yoongho Lim?   Register this Author

Register author
Yoongho Lim

Yoongho Lim

Publications by authors named "Yoongho Lim"

Are you Yoongho Lim?   Register this Author

100Publications

1495Reads

48Profile Views

Overcoming multidrug resistance by activating unfolded protein response of the endoplasmic reticulum in cisplatin-resistant A2780/CisR ovarian cancer cells.

BMB Rep 2019 Aug 12. Epub 2019 Aug 12.

Department of Biological Sciences, Sanghuh College of Life Sciences, Konkuk University, Seoul 05029; Cancer and Metabolism Institute, Konkuk University, Seoul 05029, Korea.

View Article

Download full-text PDF

Source
August 2019

The EGR1-STAT3 Transcription Factor Axis Regulates α-Melanocyte-Stimulating Hormone-Induced Tyrosinase Gene Transcription in Melanocytes.

J Invest Dermatol 2019 Jul 14;139(7):1616-1619. Epub 2019 Jan 14.

Department of Biological Sciences, Sanghuh College of Life Sciences, Konkuk University, Seoul, Republic of Korea; Cancer and Metabolism Institute, Konkuk University, Seoul, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jid.2018.12.020DOI Listing
July 2019

Inhibition of TNFα-induced interleukin-6 gene expression by barley (Hordeum vulgare) ethanol extract in BV-2 microglia.

Genes Genomics 2019 05 22;41(5):557-566. Epub 2019 Feb 22.

Department of Biological Sciences, Sanghuh College of Life Sciences, Konkuk University, Seoul, 05029, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13258-018-00781-8DOI Listing
May 2019

Byakangelicin as a modulator for improved distribution and bioactivity of natural compounds and synthetic drugs in the brain.

Phytomedicine 2019 May 17;62:152963. Epub 2019 May 17.

Department of Bioscience and Biotechnology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phymed.2019.152963DOI Listing
May 2019

Synthetic Diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates Induce Apoptosis.

Med Chem 2018 ;14(8):851-862

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 05029, Korea.

View Article

Download full-text PDF

Source
http://www.eurekaselect.com/161376/article
Publisher Site
http://dx.doi.org/10.2174/1573406414666180418143048DOI Listing
March 2019

Gomisin G Suppresses the Growth of Colon Cancer Cells by Attenuation of AKT Phosphorylation and Arrest of Cell Cycle Progression.

Biomol Ther (Seoul) 2019 Mar;27(2):210-215

Center for Medical Science Research, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4062/biomolther.2018.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430222PMC
March 2019

Design, synthesis, and biological activities of 1-aryl-(3-(2-styryl)phenyl)prop-2-en-1-ones.

Bioorg Chem 2019 03 10;83:438-449. Epub 2018 Nov 10.

Division of Bioscience and Biotechnology, BBRC, Konkuk University, Seoul 05029, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00452068183088
Publisher Site
http://dx.doi.org/10.1016/j.bioorg.2018.11.005DOI Listing
March 2019

A synthetic chalcone derivative, 2-hydroxy-3',5,5'-trimethoxychalcone (DK-139), triggers reactive oxygen species-induced apoptosis independently of p53 in A549 lung cancer cells.

Chem Biol Interact 2019 Jan 5;298:72-79. Epub 2018 Nov 5.

Department of Biological Sciences, Sanghuh College of Life Sciences, Seoul, 05029, Republic of Korea; Cancer and Metabolism Institute, Konkuk University, Seoul, 05029, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cbi.2018.11.003DOI Listing
January 2019

H and C NMR spectral assignments of 25 ethyl 2-oxocyclohex-3-enecarboxylates.

Magn Reson Chem 2018 12 19;56(12):1188-1200. Epub 2018 Jul 19.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.4778DOI Listing
December 2018

Inhibitory Effect of Synthetic Flavone Derivatives on Pan-Aurora Kinases: Induction of G2/M Cell-Cycle Arrest and Apoptosis in HCT116 Human Colon Cancer Cells.

Int J Mol Sci 2018 Dec 17;19(12). Epub 2018 Dec 17.

Department of Biological Sciences, Sanghuh College of Life Science s, Konkuk University, Seoul 05029, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms19124086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320900PMC
December 2018

The synthetic chalcone derivative 2-hydroxy-3',5,5'-trimethoxychalcone induces unfolded protein response-mediated apoptosis in A549 lung cancer cells.

Bioorg Med Chem Lett 2018 09 4;28(17):2969-2975. Epub 2018 Jul 4.

Department of Biological Sciences, Sanghuh College of Life Sciences, Konkuk University, Seoul 05029, Republic of Korea; Cancer and Metabolism Institute, Konkuk University, Seoul 05029, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2018.07.003DOI Listing
September 2018

Inhibitory Effect of Ethanolic Extract on NF-κB-Dependent CXCR3 and CXCL10 Expression in TNFα-Exposed MDA-MB-231 Breast Cancer Cells.

Int J Mol Sci 2018 Sep 3;19(9). Epub 2018 Sep 3.

Department of Biological Sciences, Sanghuh College of Life Sciences, Konkuk University, Seoul 05029, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms19092607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165157PMC
September 2018

H and C NMR characterization of 1,3,4-oxadiazole derivatives.

Magn Reson Chem 2018 08 28;56(8):782-791. Epub 2018 Feb 28.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 05029, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.4718DOI Listing
August 2018

Agerarin inhibits α-MSH-induced TYR gene transcription via STAT3 suppression independent of CREB-MITF pathway.

J Dermatol Sci 2018 Jul 30;91(1):107-110. Epub 2018 Mar 30.

Department of Biological Sciences, Sanghuh College of Life Sciences, Konkuk University, Seoul, Republic of Korea; Cancer and Metabolism Institute, Konkuk University, Seoul, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09231811183015
Publisher Site
http://dx.doi.org/10.1016/j.jdermsci.2018.03.014DOI Listing
July 2018

2,4‑Di‑tert‑butylphenol, a potential HDAC6 inhibitor, induces senescence and mitotic catastrophe in human gastric adenocarcinoma AGS cells.

Biochim Biophys Acta Mol Cell Res 2018 May 8;1865(5):675-683. Epub 2018 Feb 8.

Subtropical/Tropical Organism Gene Bank, Jeju National University, Jeju 63243, Republic of Korea; Faculty of Biotechnology, College of Applied Life Sciences, Jeju National University, SARI, Jeju 63243, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2018.02.003DOI Listing
May 2018

A Novel Synthetic Material, BMM, Accelerates Wound Repair by Stimulating Re-Epithelialization and Fibroblast Activation.

Int J Mol Sci 2018 Apr 11;19(4). Epub 2018 Apr 11.

Department of Biochemistry, School of Medicine, Jeju National University, Jeju 690-756, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms19041164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979586PMC
April 2018

A Computational-Based Approach to Identify Estrogen Receptor / Heterodimer Selective Ligands.

Mol Pharmacol 2018 03 2;93(3):197-207. Epub 2018 Jan 2.

Molecular & Environmental Toxicology Center, Department of Oncology (C.G.C., W.X.), Department of Oncology (C.G.C., F.L., C.K.S., Y.W., W.X.), and Wisconsin Clinical Sciences Center, Department of Biostatistics and Medical Informatics (M.L., M.Y.), University of Wisconsin-Madison, Madison, Wisconsin; and Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, Republic of Korea (Y.L.)

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/mol.117.108696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801554PMC
March 2018

Aurora kinase A inhibitor TCS7010 demonstrates pro-apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells.

Oncol Lett 2017 Dec 22;14(6):6571-6577. Epub 2017 Sep 22.

Department of Biological Sciences, College of Biological Science and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.

View Article

Download full-text PDF

Source
http://www.spandidos-publications.com/10.3892/ol.2017.7023
Publisher Site
http://dx.doi.org/10.3892/ol.2017.7023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686436PMC
December 2017

C-C motif chemokine receptor 1 (CCR1) is a target of the EGF-AKT-mTOR-STAT3 signaling axis in breast cancer cells.

Oncotarget 2017 Nov 10;8(55):94591-94605. Epub 2017 Oct 10.

Department of Biological Sciences, Sanghuh College of Life Sciences, Konkuk University, Seoul, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.21813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706898PMC
November 2017

Biological evaluation of 2-pyrazolinyl-1-carbothioamide derivatives against HCT116 human colorectal cancer cell lines and elucidation on QSAR and molecular binding modes.

Bioorg Med Chem 2017 10 4;25(20):5423-5432. Epub 2017 Aug 4.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 05029, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09680896173087
Publisher Site
http://dx.doi.org/10.1016/j.bmc.2017.07.062DOI Listing
October 2017

H and C NMR spectral assignments for 24 novel naphthalenylphenylpyrazolines.

Magn Reson Chem 2017 09 1;55(9):856-863. Epub 2017 Jun 1.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 05029, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.4603DOI Listing
September 2017

Synthesis and structure elucidation of polyphenols containing the N'-methyleneformohydrazide scaffold as aurora kinase inhibitors.

Magn Reson Chem 2017 09 3;55(9):864-876. Epub 2017 Jul 3.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 143-701, South Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.4611DOI Listing
September 2017

γ-Oryzanol-Rich Black Rice Bran Extract Enhances the Innate Immune Response.

J Med Food 2017 Sep 7;20(9):855-863. Epub 2017 Jul 7.

1 Department of Biological Sciences, Sanghuh College of Life Sciences, Konkuk University , Seoul, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/jmf.2017.3966DOI Listing
September 2017

γ-Oryzanol suppresses COX-2 expression by inhibiting reactive oxygen species-mediated Erk1/2 and Egr-1 signaling in LPS-stimulated RAW264.7 macrophages.

Biochem Biophys Res Commun 2017 09 18;491(2):486-492. Epub 2017 Jul 18.

Department of Biological Sciences, Sanghuh College of Life Sciences, Konkuk University, Seoul 05029, Republic of Korea; Cancer and Metabolism Institute, Konkuk University, Seoul 05029, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2017.07.016DOI Listing
September 2017

Benzoflavonoids Structure Hinders Human Colon Cancer Clonogenicity.

Med Chem 2017 ;13(2):168-175

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573406412666160525120433DOI Listing
August 2017

H and C NMR spectral assignments of flavone derivatives.

Magn Reson Chem 2017 04 23;55(4):359-366. Epub 2016 Oct 23.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, Korea.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/mrc.4535
Publisher Site
http://dx.doi.org/10.1002/mrc.4535DOI Listing
April 2017

Synthesis and biological evaluation of hesperetin derivatives as agents inducing apoptosis.

Bioorg Med Chem 2017 01 4;25(1):397-407. Epub 2016 Nov 4.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2016.11.006DOI Listing
January 2017

H and C NMR spectral assignments of naphthalenyl chalcone derivatives.

Magn Reson Chem 2016 Oct 13;54(10):842-851. Epub 2016 Jun 13.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.4458DOI Listing
October 2016

Anticancer and structure-activity relationship evaluation of 3-(naphthalen-2-yl)-N,5-diphenyl-pyrazoline-1-carbothioamide analogs of chalcone.

Bioorg Chem 2016 10 5;68:166-76. Epub 2016 Aug 5.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bioorg.2016.08.003DOI Listing
October 2016

p53-dependent and -independent mechanisms are involved in (E)-1-(2-hydroxyphenyl)-3-(2-methoxynaphthalen-1-yl)prop-2-en-1-one (HMP)-induced apoptosis in HCT116 colon cancer cells.

Biochem Biophys Res Commun 2016 Oct 15;479(4):913-919. Epub 2016 Sep 15.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 05029, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0006291X163152
Publisher Site
http://dx.doi.org/10.1016/j.bbrc.2016.09.067DOI Listing
October 2016

Euphorbia humifusa Willd exerts inhibition of breast cancer cell invasion and metastasis through inhibition of TNFα-induced MMP-9 expression.

BMC Complement Altern Med 2016 Oct 24;16(1):413. Epub 2016 Oct 24.

Department of Biological Sciences, College of Biological Science and Biotechnology, Konkuk University, Seoul, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12906-016-1404-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078950PMC
October 2016

Inhibition of PDGF-induced migration and TNF-α-induced ICAM-1 expression by maltotetraose from bamboo stem extract (BSE) in mouse vascular smooth muscle cells.

Mol Nutr Food Res 2016 09 25;60(9):2086-97. Epub 2016 May 25.

Department of Biological Sciences, College of Biological Science and Biotechnology, Konkuk University, Seoul, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mnfr.201500601DOI Listing
September 2016

Colorectal anticancer activities of polymethoxylated 3-naphthyl-5-phenylpyrazoline-carbothioamides.

Bioorg Med Chem Lett 2016 09 19;26(17):4301-9. Epub 2016 Jul 19.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2016.07.037DOI Listing
September 2016

The UPR inducer DPP23 inhibits the metastatic potential of MDA-MB-231 human breast cancer cells by targeting the Akt-IKK-NF-κB-MMP-9 axis.

Sci Rep 2016 Sep 23;6:34134. Epub 2016 Sep 23.

Department of Biological Sciences, College of Biological Science and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep34134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034246PMC
September 2016

(1) H and (13) C NMR spectral assignments of novel flavonoids bearing benzothiazepine.

Magn Reson Chem 2016 May 23;54(5):382-90. Epub 2015 Nov 23.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.4388DOI Listing
May 2016

(1) H and (13) C NMR spectral assignments of 30 novel n-methoxylated polyphenols containing thiourea skeletons.

Magn Reson Chem 2016 May 18;54(5):403-13. Epub 2016 Feb 18.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 143-701, Korea.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/mrc.4405
Publisher Site
http://dx.doi.org/10.1002/mrc.4405DOI Listing
May 2016

A synthetic isoflavone, DCMF, promotes human keratinocyte migration by activating Src/FAK signaling pathway.

Biochem Biophys Res Commun 2016 Apr 26;472(2):332-8. Epub 2016 Feb 26.

Department of Biochemistry, School of Medicine, Jeju National University, Republic of Korea; Jeju Regional Cancer Center, Jeju National University Hospital, Republic of Korea; Institute of Medical Science, Jeju National University, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2016.02.106DOI Listing
April 2016

(1) H and (13) C NMR spectral assignments of 19 novel polymethoxylated diphenylnaphthylpyrazolinylcarbothioamides.

Magn Reson Chem 2016 Mar 14;54(3):246-51. Epub 2015 Oct 14.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.4367DOI Listing
March 2016

(1) H and (13) C NMR spectral assignments of novel naphthalenylphenylpyrazolines.

Magn Reson Chem 2016 Mar 19;54(3):252-9. Epub 2015 Oct 19.

College of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 05029, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.4368DOI Listing
March 2016

A synthetic chalcone, 2'-hydroxy-2,3,5'-trimethoxychalcone triggers unfolded protein response-mediated apoptosis in breast cancer cells.

Cancer Lett 2016 03 29;372(1):1-9. Epub 2015 Dec 29.

Department of Biological Sciences, College of Biological Science and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea; Cancer and Metabolism Institute, Konkuk University, Seoul 05029, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2015.12.017DOI Listing
March 2016

A synthetic chalcone derivative, 2-hydroxy-3',5,5'-trimethoxychalcone (DK-139), suppresses the TNFα-induced invasive capability of MDA-MB-231 human breast cancer cells by inhibiting NF-κB-mediated GROα expression.

Bioorg Med Chem Lett 2016 01 30;26(1):203-8. Epub 2015 Oct 30.

Department of Biological Sciences, College of Biological Science and Biotechnology, Konkuk University, 120 Neundong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea; Cancer and Metabolism Institute, Konkuk University, Seoul 143-701, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2015.10.094DOI Listing
January 2016

Crystal structure of 2-(2,3-di-meth-oxy-naphthalen-1-yl)-3-hy-droxy-6-meth-oxy-4H-chromen-4-one.

Acta Crystallogr E Crystallogr Commun 2015 Nov 14;71(Pt 11):o842-3. Epub 2015 Oct 14.

Department of Applied Chemistry, Dongduk Women's University, Seoul 136-714, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1107/S2056989015018861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645031PMC
November 2015

Quantitative Relationships Between the Cytotoxicity of Flavonoids on the Human Breast Cancer Stem-Like Cells MCF7-SC and Their Structural Properties.

Chem Biol Drug Des 2015 Oct 31;86(4):496-508. Epub 2015 Jan 31.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cbdd.12512DOI Listing
October 2015

Crystal structure of (E)-4,6-dimeth-oxy-2-(4-meth-oxy-styr-yl)-3-methyl-benzaldehyde.

Acta Crystallogr E Crystallogr Commun 2015 Oct 26;71(Pt 10):o771. Epub 2015 Sep 26.

Department of Applied Chemistry, Dongduk Women's University, Seoul 136-714, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1107/S2056989015017363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647390PMC
October 2015

Plant-derived flavones as inhibitors of aurora B kinase and their quantitative structure-activity relationships.

Chem Biol Drug Des 2015 May 28;85(5):574-85. Epub 2014 Oct 28.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cbdd.12445DOI Listing
May 2015

Soy Isoflavone Glycitin (4'-Hydroxy-6-Methoxyisoflavone-7-D-Glucoside) Promotes Human Dermal Fibroblast Cell Proliferation and Migration via TGF-β Signaling.

Phytother Res 2015 May 11;29(5):757-69. Epub 2015 Mar 11.

Department of Medicine, School of Medicine, Jeju National University, Jeju, Korea, 690-756.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ptr.5313DOI Listing
May 2015

1H and 13C NMR spectral assignments of 18 novel polymethoxylated hydroxynaphthopyrazolylchalconoids.

Magn Reson Chem 2015 May 8;53(5):391-7. Epub 2015 Apr 8.

Division of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Seoul, 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.4225DOI Listing
May 2015

1H and 13C NMR spectral assignments of 18 novel polymethoxylated naphthochalcones bearing pyrazoline-1-carbothioamide groups.

Magn Reson Chem 2015 May;53(5):383-90

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.4217DOI Listing
May 2015

Synthesis and biological evaluation of phenyl-1H-1,2,3-triazole derivatives as anti-inflammatory agents.

Bioorg Chem 2015 Apr 20;59:1-11. Epub 2015 Jan 20.

Department of Biochemical Engineering, Gangneung-Wonju National University, Gangwon 210-702, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bioorg.2015.01.003DOI Listing
April 2015

2-Hydroxy-3,4-naphthochalcone (2H-NC) inhibits TNFα-induced tumor invasion through the downregulation of NF-κB-mediated MMP-9 gene expression.

Bioorg Med Chem Lett 2015 Jan 1;25(1):128-32. Epub 2014 Nov 1.

Department of Biological Sciences, Konkuk University, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2014.10.086DOI Listing
January 2015

Mechanism of 2',3'-dimethoxyflavanone-induced apoptosis in breast cancer stem cells: role of ubiquitination of caspase-8 and LC3.

Arch Biochem Biophys 2014 Nov 14;562:92-102. Epub 2014 Aug 14.

Faculty of Biotechnology, College of Applied Life Sciences, SARI, Jeju National University, Jeju 690-756, Republic of Korea; Subtropical Horticulture Research Institute, Jeju National University, Jeju 690-756, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.abb.2014.08.001DOI Listing
November 2014

A new synthetic 2'-hydroxy-2,4,6-trimethoxy-5',6'-naphthochalcone induces G2/M cell cycle arrest and apoptosis by disrupting the microtubular network of human colon cancer cells.

Cancer Lett 2014 Nov 1;354(2):348-54. Epub 2014 Sep 1.

Department of Biological Sciences, College of Biological Science and Biotechnology, Cancer and Metabolism Institute, Konkuk University, Seoul 143-701, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2014.08.041DOI Listing
November 2014

Crystal structure of 2-(3,4-di-meth-oxy-phen-yl)-3-hy-droxy-4H-chromen-4-one.

Acta Crystallogr Sect E Struct Rep Online 2014 Sep 13;70(Pt 9):o999-o1000. Epub 2014 Aug 13.

Department of Applied Chemistry, Dongduk Women's University, Seoul 136-714, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1107/S1600536814018212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186158PMC
September 2014

Targeting cancer cells via the reactive oxygen species-mediated unfolded protein response with a novel synthetic polyphenol conjugate.

Clin Cancer Res 2014 Aug 17;20(16):4302-13. Epub 2014 Jun 17.

Department of Biological Sciences, College of Biological Science and Biotechnology, and Cancer and Metabolism Institute, Konkuk University, Seoul, Republic of Korea.

View Article

Download full-text PDF

Source
http://clincancerres.aacrjournals.org/content/early/2014/07/
Web Search
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-14-0424DOI Listing
August 2014

3-Meth-oxy-2-[5-(naphthalen-2-yl)-4,5-di-hydro-1H-pyrazol-3-yl]phenol.

Acta Crystallogr Sect E Struct Rep Online 2014 Apr 22;70(Pt 4):o464. Epub 2014 Mar 22.

Department of Chemistry, University of Toronto, Toronto, Ontario, M5S 3H6, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1107/S1600536814005972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998579PMC
April 2014

Flavonoids promoting HaCaT migration: I. Hologram quantitative structure-activity relationships.

Phytomedicine 2014 Mar 16;21(4):560-9. Epub 2013 Nov 16.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phymed.2013.10.006DOI Listing
March 2014

Flavonoids promoting HaCaT migration: II. Molecular mechanism of 4',6,7-trimethoxyisoflavone via NOX2 activation.

Phytomedicine 2014 Mar 30;21(4):570-7. Epub 2013 Dec 30.

Department of Biochemistry School of Medicine, Jeju National University, Jeju 690-756, Republic of Korea; Institute of Medical Science, Jeju National University, Jeju 690-756, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phymed.2013.10.010DOI Listing
March 2014

Polyphenols bearing cinnamaldehyde scaffold showing cell growth inhibitory effects on the cisplatin-resistant A2780/Cis ovarian cancer cells.

Bioorg Med Chem 2014 Mar 10;22(6):1809-20. Epub 2014 Feb 10.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Hwayang-Dong 1, Kwangjin-Gu, Seoul 143-701, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09680896140009
Publisher Site
http://dx.doi.org/10.1016/j.bmc.2014.01.058DOI Listing
March 2014

Chromenylchalcones with inhibitory effects on monoamine oxidase B.

Bioorg Med Chem 2013 Dec 16;21(24):7890-7. Epub 2013 Oct 16.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Hwayang-Dong 1, Kwangjin-Ku, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2013.10.004DOI Listing
December 2013

Novel antimitotic activity of 2-hydroxy-4-methoxy-2',3'-benzochalcone (HymnPro) through the inhibition of tubulin polymerization.

J Agric Food Chem 2013 Dec 12;61(51):12588-97. Epub 2013 Dec 12.

Department of Biological Sciences, College of Biological Science and Biotechnology, Cancer and Metabolism Institute, Konkuk University , Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jf4034688DOI Listing
December 2013

Benzochalcones bearing pyrazoline moieties show anti-colorectal cancer activities and selective inhibitory effects on aurora kinases.

Bioorg Med Chem 2013 Nov 18;21(22):7018-24. Epub 2013 Sep 18.

Department of Biological Sciences, Konkuk University, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2013.09.014DOI Listing
November 2013

Transcriptional regulation of the growth-regulated oncogene α gene by early growth response protein-1 in response to tumor necrosis factor α stimulation.

Biochim Biophys Acta 2013 Oct 18;1829(10):1066-74. Epub 2013 Jul 18.

Department of Biological Sciences, College of Biological Science and Biotechnology, Konkuk University, Seoul 143-701, Republic of Korea; Cancer and Metabolism Institute, Konkuk University, Seoul 143-701, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbagrm.2013.07.005DOI Listing
October 2013

The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells.

Carcinogenesis 2013 Sep 20;34(9):2080-9. Epub 2013 May 20.

Department of Biological Sciences, College of Biological Science and Biotechnology, Research Center for Transcription Control, Konkuk University, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgt169DOI Listing
September 2013

Complete assignments of 1H and 13C NMR data for 21 naphthalenyl-phenyl-pyrazoline derivatives.

Magn Reson Chem 2013 Sep 1;51(9):593-9. Epub 2013 Jul 1.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.3981DOI Listing
September 2013

1H and 13C NMR spectral assignments of chalcones bearing pyrazoline-carbothioamide groups.

Magn Reson Chem 2013 Aug 19;51(8):500-8. Epub 2013 Jun 19.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.3971DOI Listing
August 2013

Chromenylchalcones showing cytotoxicity on human colon cancer cell lines and in silico docking with aurora kinases.

Bioorg Med Chem 2013 Jul 15;21(14):4250-8. Epub 2013 May 15.

Department of Biological Sciences, College of Biological Science and Biotechnology, Konkuk University, Seoul 143-701, South Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2013.04.086DOI Listing
July 2013

1H and 13C NMR spectral assignments of 2'-hydroxychalcones.

Magn Reson Chem 2013 Jun 17;51(6):364-70. Epub 2013 Apr 17.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.3949DOI Listing
June 2013

(E)-1-(3,5-Di-meth-oxy-phen-yl)-3-(3-meth-oxy-phen-yl)prop-2-en-1-one.

Acta Crystallogr Sect E Struct Rep Online 2013 May 5;69(Pt 5):o666. Epub 2013 Apr 5.

Department of Applied Chemistry, Dongduk Women's University, Seoul 136-714, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1107/S1600536813008982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647862PMC
May 2013

(E)-3-(3,5-Dimeth-oxy-phen-yl)-1-(2-meth-oxy-phen-yl)prop-2-en-1-one.

Acta Crystallogr Sect E Struct Rep Online 2013 Apr 9;69(Pt 4):o514. Epub 2013 Mar 9.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1107/S1600536813006302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629573PMC
April 2013

Effects of flavone derivatives on antigen-stimulated degranulation in RBL-2H3 cells.

Chem Biol Drug Des 2013 Feb 19;81(2):228-37. Epub 2012 Nov 19.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Korea National Institute of Animal Science, Rural Development Administration, Suwon 441-706, Korea Cell Activation Research Institute, Gyeonggi-do 464-870, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cbdd.12067DOI Listing
February 2013

Design, synthesis and inhibitory activities of naringenin derivatives on human colon cancer cells.

Bioorg Med Chem Lett 2013 Jan 5;23(1):232-8. Epub 2012 Nov 5.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2012.10.130DOI Listing
January 2013

Transcriptional regulation of the interleukin-11 gene by oncogenic Ras.

Carcinogenesis 2012 Dec 1;33(12):2467-76. Epub 2012 Oct 1.

Department of Biomedical Science and Technology, SMART Institute of Advanced Biomedical Science, Research Center for Transcription Control, Konkuk University, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgs297DOI Listing
December 2012

(E)-3-(3,5-Dimeth-oxy-phen-yl)-1-(1-hy-droxy-naphthalen-2-yl)prop-2-en-1-one.

Acta Crystallogr Sect E Struct Rep Online 2012 Dec 24;68(Pt 12):o3403. Epub 2012 Nov 24.

Jeonju Center, Korea Basic Science Center (KBSI), Jeonju 561-765, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1107/S1600536812046715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588993PMC
December 2012

1H and 13C NMR spectral assignments of novel chromenylchalcones.

Magn Reson Chem 2012 Nov 7;50(11):759-64. Epub 2012 Sep 7.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, South Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.3873DOI Listing
November 2012

Production of a novel quercetin glycoside through metabolic engineering of Escherichia coli.

Appl Environ Microbiol 2012 Jun 6;78(12):4256-62. Epub 2012 Apr 6.

Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Seoul, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AEM.00275-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370505PMC
June 2012

2'-Hydroxyflavanone induces apoptosis through Egr-1 involving expression of Bax, p21, and NAG-1 in colon cancer cells.

Mol Nutr Food Res 2012 May;56(5):761-74

SMART Institute of Advanced Biomedical Science, Konkuk University, Seoul, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mnfr.201100651DOI Listing
May 2012

Inhibitory effect of the antidepressant imipramine on NF-κB-dependent CXCL1 expression in TNFα-exposed astrocytes.

Int Immunopharmacol 2012 Apr 8;12(4):547-55. Epub 2012 Feb 8.

Department of Biomedical Science and Technology, Research Center for Transcription Control, SMART Institute of Advanced Biomedical Science, Konkuk University, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15675769120003
Publisher Site
http://dx.doi.org/10.1016/j.intimp.2012.01.011DOI Listing
April 2012

Isoflavones inhibit the clonogenicity of human colon cancer cells.

Bioorg Med Chem Lett 2012 Apr 13;22(8):2664-9. Epub 2012 Mar 13.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2012.03.027DOI Listing
April 2012

Flavanones inhibit the clonogenicity of HCT116 cololectal cancer cells.

Int J Mol Med 2012 Mar 12;29(3):403-8. Epub 2011 Dec 12.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, MoleNBio, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ijmm.2011.857DOI Listing
March 2012

TNF-α increases lipogenesis via JNK and PI3K/Akt pathways in SZ95 human sebocytes.

J Dermatol Sci 2012 Mar 20;65(3):179-88. Epub 2011 Nov 20.

Laboratory of Pathology, College of Oriental Medicine, Daejeon University, Daejeon 300-716, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdermsci.2011.11.005DOI Listing
March 2012

Synthesis of methoxybenzoflavones and assignments of their NMR data.

Magn Reson Chem 2012 Jan 8;50(1):62-7. Epub 2012 Feb 8.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.3790DOI Listing
January 2012

3'-Chloro-5,7-dimethoxyisoflavone inhibits TNFα-induced CXCL10 gene transcription by suppressing the NF-κB pathway in HCT116 human colon cancer cells.

Int Immunopharmacol 2011 Dec 22;11(12):2104-11. Epub 2011 Sep 22.

Department of Biomedical Science and Technology, Konkuk University Medical Center, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.intimp.2011.09.003DOI Listing
December 2011

Identification and structure elucidation of a p-phenoxybenzaldehyde in bamboo shoots by HPLC-ESI/MS/MS and NMR.

J Agric Food Chem 2011 Nov 14;59(21):11579-84. Epub 2011 Oct 14.

Gyeong-In Regional Korea Food and Drug Administration, Juan-Dong 120, Nam-Gu, Incheon 402-835, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jf2025727DOI Listing
November 2011

A compound isolated from Schisandra chinensis induces apoptosis.

Bioorg Med Chem Lett 2011 Oct 22;21(20):6054-7. Epub 2011 Aug 22.

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2011.08.065DOI Listing
October 2011

Relationship between the structures of flavonoids and their NF-κB-dependent transcriptional activities.

Bioorg Med Chem Lett 2011 Oct 22;21(20):6036-41. Epub 2011 Aug 22.

Department of Biomedical Science and Technology, SMART-Institute of Advanced Biomedical Science, RCTC, Konkuk University, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0960894X1101176
Publisher Site
http://dx.doi.org/10.1016/j.bmcl.2011.08.077DOI Listing
October 2011

In silico study of the ion channel formed by tolaasin I produced by Pseudomonas tolaasii.

J Microbiol Biotechnol 2011 Oct;21(10):1097-100

Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4014/jmb.1103.03026DOI Listing
October 2011

The tricyclic antidepressant imipramine induces autophagic cell death in U-87MG glioma cells.

Biochem Biophys Res Commun 2011 Sep 26;413(2):311-7. Epub 2011 Aug 26.

Department of Biomedical Science and Technology, Research Center for Transcription Control, SMART Institute of Advanced Biomedical Science, Konkuk University, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2011.08.093DOI Listing
September 2011

A Tcf/Lef element within the enhancer region of the human NANOG gene plays a role in promoter activation.

Biochem Biophys Res Commun 2011 Jul 13;410(3):637-42. Epub 2011 Jun 13.

Department of Biomedical Science and Technology, Research Center for Transcription Control, Konkuk University, Seoul 143-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2011.06.044DOI Listing
July 2011

Estrogen receptor beta stimulates Egr-1 transcription via MEK1/Erk/Elk-1 cascade in C6 glioma cells.

BMB Rep 2011 Jul;44(7):452-7

Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Ansan, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5483/BMBRep.2011.44.7.452DOI Listing
July 2011