Publications by authors named "Yongjun Peng"

9 Publications

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Preparation of magnetic powdered carbon/nano-FeO composite for efficient adsorption and degradation of trichloropropyl phosphate from water.

J Hazard Mater 2021 08 27;416:125765. Epub 2021 Mar 27.

State Key Joint Laboratory of Environment Simulation and Pollution Control (SKLESPC), Beijing Key Laboratory for Emerging Organic Contaminants Control, School of Environment, Tsinghua University, Beijing 100084, China. Electronic address:

Trichloropropyl phosphate (TCPP) as a widely used typical chlorinated organophosphate flame retardant has received significant attention because of its widespread presence in water and negative effects on human health. In this study, a ball-milling method was used to prepare a magnetic powdered carbon adsorbent (PC/nano-FeO composite) for TCPP removal via adsorption and catalytic degradation. The effect of FeO content on TCPP adsorption and degradation performance by PC/nano-FeO composite was investigated. The PC/nano-FeO composite prepared by high FeO content (25%) was not favorable for TCPP adsorption and degradation. However, the PC/FeO containing low FeO content (10%) had insufficient magnetic separation ability from water. The synthesized PC/nano-FeO composite with a FeO/PC mass ratio of 1/5 exhibited a maximum adsorption capacity of 2682.1 μg/g as well as a complete TCPP degradation within 3 h in a Fenton-like system. Moreover, the possible break sites of TCPP and its degradation pathway were proposed based on theoretical calculation and experimental analysis. Regeneration studies showed that PC/nano-FeO composite had high reusability and adsorption capacity in six cycles, while its catalytic performance declined in the multiple reuse cycles. This strategy could be extended to prepare other magnetic powdered adsorbents for organic pollutant adsorption and degradation.
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http://dx.doi.org/10.1016/j.jhazmat.2021.125765DOI Listing
August 2021

Cortical myelin content mediates differences in affective temperaments.

J Affect Disord 2021 03 14;282:1263-1271. Epub 2021 Jan 14.

Key Laboratory of Brain, Cognition and Education Sciences (South China Normal University), Ministry of Education; School of Psychology, Center for Studies of Psychological Application; Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, Guangzhou, 510631, China. Electronic address:

Background: Affective temperaments are regarded as subclinical forms and precursors of mental disorders. It may serve as candidates to facilitate the diagnosis and prediction of mental disorders. Cortical myelination likely characterizes the neurodevelopment and the evolution of cognitive functions and reflects brain functional demand. However, little is known about the relationship between affective temperaments and myelin plasticity. This study aims to analyze the association between the affective temperaments and cortical myelin content (CMC) in human brain.

Methods: We measured affective temperaments using the Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire (TEMPS-A) on 106 healthy adults and used the ratio of T1- and T2-weighted images as the proxy for CMC. Using the unsupervised k-means clustering algorithm, we classified the cortical gray matter into heavily, intermediately, and lightly myelinated regions. The correlation between affective temperaments and CMC was calculated separately for different myelinated regions.

Results: Hyperthymic temperament correlated negatively with CMC in the heavily myelinated (right postcentral gyrus and bilateral precentral gyrus) and lightly myelinated (bilateral frontal and lateral temporal) regions. Cyclothymic temperament showed a downward parabola-like correlation with CMC across the heavily, intermediately, and lightly myel0inated areas of the bilateral parietal-temporal regions.

Limitations: The analysis was constrained to cortical regions. The results were obtained from healthy subjects and we did not acquired data from patients of affective disorder, which may compromise the generalizability of the present findings.

Conclusion: The findings suggest that hyperthymic and cyclothymic temperaments have a CMC basis in extensive brain regions.
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http://dx.doi.org/10.1016/j.jad.2021.01.038DOI Listing
March 2021

Bidirectional association between irritable bowel syndrome and restless legs syndrome: a systematic review and meta-analysis.

Sleep Med 2021 01 4;77:104-111. Epub 2020 Dec 4.

The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. Electronic address:

Background: Several observational studies have shown that patients with irritable bowel syndrome (IBS) may have a high risk of restless legs syndrome (RLS). This systematic review and meta-analysis aimed to comprehensively investigate the bidirectional association between IBS and RLS.

Methods: All conservational studies on IBS and RLS were searched in MEDLINE (assessed by PubMed), Embase, Web of Science, CINAHL, the Cochrane Library database and Google Scholar from inception to June 14, 2020. The Newcastle-Ottawa Scale and Agency for Healthcare Research and Quality were used to assess the methodological quality of the cohort and cross-sectional studies, respectively. The pooled odds ratio (OR) and 95% confidence interval (CI) were calculated using Reviewer Manager 5.3.

Result: A total of five cross-sectional studies of moderate methodological quality and one cohort study of high methodological quality were included in our review. Four cross-sectional studies and one cohort study involving 86 438 individuals met the criteria of IBS predicating the onset of RLS. Patients with IBS had a nearly three-fold increased odds of RLS compared with controls (OR = 2.60, 95%CI: 2.17-3.12, P < 0.00001; I = 48%, P = 0.11). Three sensitivity analyses confirmed the robustness of the pooled result. Two cross-sectional studies involving 3581 individuals met the criteria of RLS predicating the onset of IBS. RLS patients had a nearly four-fold increased odds of IBS compared with controls without RLS (OR = 3.87, 95%CI: 1.73-8.66, P = 0.0010; I = 77%, P = 0.04).

Conclusion: In this systematic review and meta-analysis, we found a substantial bidirectional association between IBS and RLS. More prospective, high-quality, population-based studies are warranted in the future.
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http://dx.doi.org/10.1016/j.sleep.2020.12.002DOI Listing
January 2021

Research Trends of Acupuncture Therapy on Cancer Over the Past Two Decades: A Bibliometric Analysis.

Integr Cancer Ther 2020 Jan-Dec;19:1534735420959442

The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

Purpose: Acupuncture has been used for managing cancer-related symptoms. However, there are still few studies concerning the overall trends in acupuncture therapy on cancer based on bibliometric analysis. This study aims to demonstrate the current status and trends in this field over the past 2 decades.

Methods: Articles were retrieved from the Web of Science from 2000 to 2019. CiteSpace was used for co-authorship network of countries/institutions, dual-map analysis, and detecting the keywords with citation bursts. VOSviewer was used to construct networks based on co-authorship and co-citation analysis of authors, and co-occurrence of keywords.

Results: A total of 927 articles and reviews were included in the final analysis. The number of publications has steadily increased with some fluctuations among years. The country and institution contributing most to this field are the USA and Memorial Sloan Kettering Cancer Center. Mao JJ was the most productive author and Molassiotis A ranked first in the cited authors. The co-occurrence analysis revealed 5 clusters (including "clinical trials," "clinical studies on chemotherapy/radiation-induced symptoms," "CAM therapy for cancer," "clinical studies on vasomotor symptoms," and "systematic reviews"). Most recent keyword bursts were "neuropathic pain," "arthralgia," "prevention," "supportive care," and "integrative medicine".

Conclusions: The annual publication output would increase rapidly in the next decade, which shows a promising future in this research field. Future research hotspots would focus on the role of acupuncture in neuropathic pain, arthralgia, prevention, supportive care, and integrative medicine.
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http://dx.doi.org/10.1177/1534735420959442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675915PMC
August 2021

Bamboo-Shaped Carbon Nanotubes on Coal Fly Ash Cenospheres for Pb(II) Adsorption.

J Nanosci Nanotechnol 2020 Aug;20(8):5089-5095

School of Material Science and Engineering, Xi'an University of Architecture and Technology, Xi'an 710054, Shaanxi Province, P. R. China.

The structural defects of bamboo-shaped carbon nanotubes (B-CNTs) provide abundant active sites for ion adsorption during wastewater treatment. However, a suitable supporting material for the growth of B-CNTs growth is less reported. In this paper, the catalytic growth of B-CNTs on the cenospheres (CSs) of coal fly ash was studied. The results showed that all CSs were covered by a layer of B-CNTs during the chemical vapor deposition (CVD) process, regardless of the fluctuation of the iron distribution from 0.52 to 2.09 wt%. B-CNTs with a diameter of 30-40 nm shared a similar morphology of compartment structures, which were uniformly scattered on the surfaces of the CSs and formed a 3D network structure. A high level of structural defects was present on the B-CNTs, which was denoted by an / value of 1.77 via Raman spectrum analysis. Adsorption experiments of the as-prepared [email protected] revealed an excellent adsorption capacity for lead ions of 37.32 mg/g (pH 7, initial concentration of 70 mg/L). By excluding the function of CSs, the adsorption capacity of the pure B-CNTs was estimated to be as high as 275.19 mg/g, which has not been previously reported.
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http://dx.doi.org/10.1166/jnn.2020.18480DOI Listing
August 2020

[Clinical observation of " needles therapy" in treating acute cerebral infarction and its effect on autophagy].

Zhongguo Zhen Jiu 2018 May;38(5):4573-61

The Affiliated Hospital of Nanjing University of CM, Nanjing 210029, Jiangsu Province, China.

Objective: To observe the difference of clinical efficacy between " needles therapy" and conventional acupuncture in patients with acute cerebral infarction (ACI) and its relationship with autophagy.

Methods: Sixty patients with ACI were randomly divided into an observation group (30 cases and 2 dropping) and a control group (30 cases and 3 dropping). Conventional drugs were applied in the two groups. In the observation group, acupuncture was applied at Dazhui (GV 14), Fengchi (GB 20), Qiangjian (GV 18), Baihui (GV 20), Shenting (GV 24), Yintang (GV 29), Shuigou (GV 26), Quchi (LI 11, affected side), Hegu (LI 4, affected side), Zusanli (ST 36, affected side), and EA was connected at Baihui (GV 20) and Yintang (GV 29). After 30 min, the EA and non-governor vessel acupoints were removed, and the governor vessel points were continued for 20 min. Twirling was used twice every 5 min, 1 min a time. In the control group, acupuncture was applied at Baihui (GV 20), Yintang (GV 29), Quchi (LI 11, affected side), Waiguan (TE 5, affected side), Shousanli (LI 10, affected side), Hegu (LI 4), Zusanli (ST 36), Sanyinjiao (SP 6, affected side), Taixi (KI 3, affected side), Taichong (LR 3, affected side). EA was connected at Zusanli (ST 36) and Hegu (LI 4). The treatment was given for 10 days, once every day with needle retained for 30 min. National Institute of Health stroke scale (NIHSS), mini-mental state examination (MMSE), modified Barthel index (MBI) scores were observed before and after treatment in the two groups. The clinical efficacy, the changes of contents of LC3-II and Beclin1 in peripheral serum were judged.

Results: After treatment, NIHSS score was lower than that before treatment, and MMSE score and MBI score were higher than those before treatment (all <0.01), and the result in the observation group was better than that in the control group (all <0.05). Contents of LC3-Ⅱ and Beclin1 in peripheral serum were higher than those before treatment in the two groups (both <0.01), and the result in the observation group was better than that in the control group (both <0.05). The total effective rate in the observation group was 92.9% (26/28), which was better than 70.4% (19/27) in the control group (both <0.05).

Conclusion: " needles therapy" have better effect to relieve the clinical symptoms of patients with acute cerebral infarction than conventional acupuncture, which may be related to the increasing number of autophagic bodies and autophagy activity.
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http://dx.doi.org/10.13703/j.0255-2930.2018.05.001DOI Listing
May 2018

Electro-acupuncture decreases 5-HT, CGRP and increases NPY in the brain-gut axis in two rat models of Diarrhea-predominant irritable bowel syndrome(D-IBS).

BMC Complement Altern Med 2015 Sep 29;15:340. Epub 2015 Sep 29.

Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu Province, China.

Background: To examine whether electro-acupuncture (EA) could decrease 5-hydroxytryptamine (5-HT) and calcitonin gene-related peptide (CGRP), and increase neuro-peptide Y (NPY) in the brain-gut axis (BGA) in D-IBS using rat models.

Methods: Rats were randomly exposed to unpredictable chronic stress for 3 weeks followed by 1-hour acute restraint stress (CAS) after 7 days of rest, or daily gavage of Senna decoction (6 g/kg) plus chronic restraint stress (for a duration of 2 h, starting from 1 h prior to the gavage) for 2 weeks (ISC). The content of 5-HT, CGRP and NPY in the distal colon, spinal cord, hypothalamus was examined at the end of the treatment.

Results: 1. The two rat models exhibited similar characteristics, e.g., increased number of fecal pellets expelled in 1 h, decreased sacchar-intake, decreased CRD, elevated 5-HT, CGRP content and decreased NPY in the distal colon, spinal cord, hypothalamus (P < 0.05 vs. that in healthy control rats). 2. A series of equations was developed based on correlation regression analysis. The analysis results demonstrated that 5-HT mediates the changes in hypothalamus, spinal cord and colon. 5-HT and CGRP in spinal cord was closely correlated with general behavior evaluation and other transmitters in BGA.

Conclusion: 1. In comparison to 5-HT, CGRP and NPY (particularly in the spinal cord) had closer relationship with the D-IBS symptoms induced by either stress factors or Senna decotion. 2. EA treatment could restore the brain-gut axis to balanced levels.
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http://dx.doi.org/10.1186/s12906-015-0863-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589130PMC
September 2015

Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury.

Neural Regen Res 2012 Dec;7(36):2901-6

Department of Acupuncture and Rehabilitation, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.

This study used electroacupuncture at Renzhong (DU26) and Baihui (DU20) in a rat model of cerebral ischemia/reperfusion injury. Neurological deficit scores, western blotting, and reverse transcription-PCR results demonstrated that electroacupuncture markedly reduced neurological deficits, decreased corpus striatum aquaporin-4 protein and mRNA expression, and relieved damage to the blood-brain barrier in a rat model of cerebral ischemia/reperfusion injury. These results suggest that electroacupuncture most likely protects the blood-brain barrier by regulating aquaporin-4 expression following cerebral ischemia/reperfusion injury.
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http://dx.doi.org/10.3969/j.issn.1673-5374.2012.36.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190948PMC
December 2012

Dissolution of fine and intermediate sized galena particles and their interactions with iron hydroxide colloids.

J Colloid Interface Sci 2010 Jul 15;347(1):127-31. Epub 2010 Mar 15.

School of Chemical Engineering, University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia.

Dissolution of fine (-10 microm) and intermediate (+10-53 microm) galena particles was studied in the presence and absence of iron hydroxide colloids at pH 9 with nitrogen and oxygen purging. X-ray photoelectron spectroscopy (XPS) measurements and ethylene diamine-tetra acid (EDTA) extraction of the galena particles after dissolution indicate that galena dissolution is strongly dependent on particle size. Fine galena particles produced a much higher amount of lead hydroxide species per surface area than intermediate galena particles. Gas purging only affected galena dissolution slightly. More iron hydroxide colloids adsorbed on fine particles. Zeta potential measurements indicate that galena dissolution enhances the adsorption of iron hydroxide colloids due to the electrostatic attraction between lead hydroxide products and iron hydroxide colloids at pH 9. This explains the stronger affinity of iron hydroxide colloids to fine galena particles than intermediate galena particles. This study has an important implication in sulfide flotation where iron hydroxide colloids play a dominant role in mineral depression.
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http://dx.doi.org/10.1016/j.jcis.2010.03.027DOI Listing
July 2010
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