Publications by authors named "YongWon Choi"

100Publications

Regulation of T cell-associated tissues and T cell activation by RANKL-RANK-OPG.

J Bone Miner Metab 2021 Jan 12. Epub 2021 Jan 12.

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

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January 2021

Protocadherin-7 contributes to maintenance of bone homeostasis through regulation of osteoclast multinucleation.

BMB Rep 2020 Sep;53(9):472-477

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

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September 2020

Mice Lacking the Purinergic Receptor P2X5 Exhibit Defective Inflammasome Activation and Early Susceptibility to .

J Immunol 2020 Aug 15;205(3):760-766. Epub 2020 Jun 15.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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August 2020

CD44 Can Compensate for IgSF11 Deficiency by Associating with the Scaffold Protein PSD-95 during Osteoclast Differentiation.

Int J Mol Sci 2020 Apr 10;21(7). Epub 2020 Apr 10.

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

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April 2020

IgSF11 regulates osteoclast differentiation through association with the scaffold protein PSD-95.

Bone Res 2020 10;8. Epub 2020 Feb 10.

1Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104 USA.

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February 2020

Methylosome protein 50 associates with the purinergic receptor P2X5 and is involved in osteoclast maturation.

FEBS Lett 2020 01 31;594(1):144-152. Epub 2019 Aug 31.

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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January 2020

Flrt2 is involved in fine-tuning of osteoclast multinucleation.

BMB Rep 2019 Aug;52(8):514-519

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

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August 2019

The purinergic receptor P2X5 contributes to bone loss in experimental periodontitis.

BMB Rep 2018 Sep;51(9):468-473

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

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September 2018

Actin-binding LIM protein 1 regulates receptor activator of NF-κB ligand-mediated osteoclast differentiation and motility.

BMB Rep 2018 Jul;51(7):356-361

Center for Metabolic Function Regulation (CMFR), Wonkwang University School of Medicine, Iksan 54538, Korea; Department of Oral Microbiology and Immunology, Wonkwang University, Iksan 54538, Korea; Institute of BiomaterialsㆍImplant, College of Dentistry, Wonkwang University, Iksan 54538, Korea.

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July 2018

TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis.

Cell Rep 2018 01;22(5):1250-1262

Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. Electronic address:

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January 2018

Updating osteoimmunology: regulation of bone cells by innate and adaptive immunity.

Nat Rev Rheumatol 2018 03 11;14(3):146-156. Epub 2018 Jan 11.

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, 421 Curie Boulevard, Philadelphia, Pennsylvania 19104, USA.

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March 2018

Ablation of Gsα signaling in osteoclast progenitor cells adversely affects skeletal bone maintenance.

Bone 2018 04 26;109:86-90. Epub 2017 Nov 26.

Department of Orthopaedic Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Center for Research in FOP and Related Disorders, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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April 2018

TNF superfamily receptor OX40 triggers invariant NKT cell pyroptosis and liver injury.

J Clin Invest 2017 Jun 24;127(6):2222-2234. Epub 2017 Apr 24.

Immunobiology and Transplant Science Center, Houston Methodist Research Institute, and.

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June 2017

Acidification of uterine epithelium during embryo implantation in mice.

Biol Reprod 2017 01;96(1):232-243

Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.

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January 2017

Dendritic cell expression of the signaling molecule TRAF6 is required for immune tolerance in the lung.

Int Immunol 2017 02;29(2):71-78

Academy of Immunology and Microbiology, Institute for Basic Science, Pohang 37666, Republic of Korea.

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February 2017

Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways.

Sci Rep 2017 03 24;7:45140. Epub 2017 Mar 24.

Department of Orthopaedic Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

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March 2017

The purinergic receptor P2X5 regulates inflammasome activity and hyper-multinucleation of murine osteoclasts.

Sci Rep 2017 03 15;7(1):196. Epub 2017 Mar 15.

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

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March 2017

Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus.

Nat Commun 2016 Feb 29;7:10562. Epub 2016 Feb 29.

Molecular Pathogenesis Program, Kimmel Center for Biology and Medicine at the Skirball Institute, New York University School of Medicine, 540 First Avenue, New York, New York 10016, USA.

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February 2016

Involvement of Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-induced Incomplete Cytokinesis in the Polyploidization of Osteoclasts.

J Biol Chem 2016 Feb 15;291(7):3439-54. Epub 2015 Dec 15.

the Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104,

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February 2016

Acetyl CoA Carboxylase 2 Is Dispensable for CD8+ T Cell Responses.

PLoS One 2015 14;10(9):e0137776. Epub 2015 Sep 14.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States of America; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States of America.

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May 2016

Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system.

Immunol Rev 2015 Jul;266(1):72-92

Institute for Immunology and Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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July 2015

The scaffold protein RACK1 mediates the RANKL-dependent activation of p38 MAPK in osteoclast precursors.

Sci Signal 2015 Jun 2;8(379):ra54. Epub 2015 Jun 2.

Department of Life Science, Ewha Womans University, Seoul 120-750, South Korea. Research Center for Cellular Homeostasis, Ewha Womans University, Seoul 120-750, South Korea.

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June 2015

Transmembrane protein 64 reciprocally regulates osteoblast and adipocyte differentiation by modulating Wnt/β-catenin signaling.

Bone 2015 Sep 13;78:165-73. Epub 2015 May 13.

University of Pennsylvania Perelman School of Medicine, Department of Pathology and Laboratory Medicine, Philadelphia, PA 19104, USA. Electronic address:

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September 2015

Glycogen synthase kinase 3β ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production.

Nat Commun 2015 Apr 1;6:6765. Epub 2015 Apr 1.

Department of Life Science and the Research Center for Cellular Homeostasis, Ewha Womans University, Seoul 120-750, South Korea.

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April 2015

FOXO1 regulates dendritic cell activity through ICAM-1 and CCR7.

J Immunol 2015 Apr 18;194(8):3745-55. Epub 2015 Mar 18.

Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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April 2015

FOXO1 mediates RANKL-induced osteoclast formation and activity.

J Immunol 2015 Mar 18;194(6):2878-87. Epub 2015 Feb 18.

Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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March 2015

Microbiota-Independent Ameliorative Effects of Antibiotics on Spontaneous Th2-Associated Pathology of the Small Intestine.

PLoS One 2015 17;10(2):e0118795. Epub 2015 Feb 17.

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, 19104, United States of America.

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January 2016

Changes in the BDNF-immunopositive cell population of neocortical layers I and II/III after focal cerebral ischemia in rats.

Brain Res 2015 Apr 12;1605:76-82. Epub 2015 Feb 12.

Department of Occupational Therapy, Inje University, Gimhae 621-749, Republic of Korea; U-Healthcare & Anti-aging Research Center, Inje University, Gimhae 621-749, Republic of Korea. Electronic address:

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April 2015

Skeletal consequences of RANKL-blocking antibody (IK22-5) injections during growth: mouse strain disparities and synergic effect with zoledronic acid.

Bone 2015 Apr 20;73:51-9. Epub 2014 Dec 20.

INSERM, UMR-957, Equipe Ligue Nationale Contre le Cancer 2012, Nantes F-44035, France; Université de Nantes, Faculté de Médecine, Laboratoire de physiopathologie de la résorption osseuse et thérapie des tumeurs osseuses primitives, Nantes F-44035, France.

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April 2015

Biology of the RANKL-RANK-OPG System in Immunity, Bone, and Beyond.

Front Immunol 2014 20;5:511. Epub 2014 Oct 20.

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA , USA.

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November 2014

IL-18 synergizes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals.

J Immunol 2014 Oct 8;193(8):3992-4001. Epub 2014 Sep 8.

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104; and

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October 2014

Kruppel-like factor 4 attenuates osteoblast formation, function, and cross talk with osteoclasts.

J Cell Biol 2014 Mar 10;204(6):1063-74. Epub 2014 Mar 10.

Department of Pharmacology, Medical Research Center for Gene Regulation and BK21 plus, Chonnam National University Medical School, Gwangju 501-746, Korea.

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March 2014

Regulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity.

J Immunol 2014 Apr 24;192(7):3190-9. Epub 2014 Feb 24.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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April 2014

Identification of novel thymic epithelial cell subsets whose differentiation is regulated by RANKL and Traf6.

PLoS One 2014 21;9(1):e86129. Epub 2014 Jan 21.

Department of Medicine, Division of Clinical Immunology, The Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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October 2014

Distinct roles of TRAF6 at early and late stages of muscle pathology in the mdx model of Duchenne muscular dystrophy.

Hum Mol Genet 2014 Mar 24;23(6):1492-505. Epub 2013 Oct 24.

Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, KY 40202, USA and.

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March 2014

Medullary thymic epithelial cell depletion leads to autoimmune hepatitis.

J Clin Invest 2013 Aug 15;123(8):3510-24. Epub 2013 Jul 15.

Department of Medicine/Clinical Immunology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

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August 2013

Tmem64 modulates calcium signaling during RANKL-mediated osteoclast differentiation.

Cell Metab 2013 Feb;17(2):249-60

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

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February 2013

Tumor necrosis factor receptor-associated factor 1 influences KRN/I-Ag7 mouse arthritis autoantibody production.

J Clin Immunol 2013 May 26;33(4):759-66. Epub 2013 Jan 26.

Department of Rheumatology, First Affiliated Hospital of Soochow University, Soochow, People's Republic of China.

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May 2013

Reciprocal interaction between TRAF6 and notch signaling regulates adult myofiber regeneration upon injury.

Mol Cell Biol 2012 Dec 1;32(23):4833-45. Epub 2012 Oct 1.

Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky, USA.

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December 2012

OX40 signaling favors the induction of T(H)9 cells and airway inflammation.

Nat Immunol 2012 Oct 29;13(10):981-90. Epub 2012 Jul 29.

Transplant Research Center, Brigham and Women's Hospital and Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA.

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October 2012

Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging.

Aging Cell 2012 Aug 11;11(4):704-13. Epub 2012 Jun 11.

Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.

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August 2012

IL-17 mediates estrogen-deficient osteoporosis in an Act1-dependent manner.

J Cell Biochem 2012 Sep;113(9):2895-902

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.

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September 2012

The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms.

Mol Cell Biol 2012 Apr 30;32(7):1248-59. Epub 2012 Jan 30.

Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky, USA.

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April 2012

RANKL induces organized lymph node growth by stromal cell proliferation.

J Immunol 2012 Feb 30;188(3):1245-54. Epub 2011 Dec 30.

Centre National de la Recherche Scientifique, Laboratoire d'Immunopathologie et Chimie Thérapeutique, Unité Propre de Recherche 9021, Institut de Biologie Moléculaire et Cellulaire, Université de Strasbourg, 67084 Strasbourg, France.

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February 2012

Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit.

Proc Natl Acad Sci U S A 2011 Mar 14;108(13):5342-7. Epub 2011 Mar 14.

Centre National de la Recherche Scientifique, Laboratory of Therapeutic Immunology and Chemistry, Unité Propre de Recherche 9021, Institut de Biologie Moléculaire et Cellulaire, University of Strasbourg, 67084 Strasbourg, France.

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March 2011

Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice.

J Cell Biol 2010 Dec;191(7):1395-411

Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.

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December 2010

ATP6v0d2 deficiency increases bone mass, but does not influence ovariectomy-induced bone loss.

Biochem Biophys Res Commun 2010 Dec 30;403(1):73-8. Epub 2010 Oct 30.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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December 2010

EGR-2 is not required for in vivo CD4 T cell mediated immune responses.

PLoS One 2010 Sep 23;5(9):e12904. Epub 2010 Sep 23.

Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America.

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September 2010

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

Blood 2010 Jun 29;115(23):4750-7. Epub 2010 Mar 29.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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June 2010

Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland.

Proc Natl Acad Sci U S A 2010 Feb 28;107(7):2989-94. Epub 2010 Jan 28.

Ecole Polytechnique Fédérale de Lausanne, Swiss Institute for Experimental Cancer Research (ISREC), NCCR Molecular Oncology, CH-1015 Lausanne, Switzerland.

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February 2010

Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1.

J Biol Chem 2010 Feb 26;285(8):5224-31. Epub 2009 Dec 26.

National Research Laboratory for Regulation of Bone Metabolism and Disease, Medical Research Center for Gene Regulation, Research Institute of Medical Sciences, Brain Korea 21, Chonnam National University Medical School, Gwangju 501-746, Korea.

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February 2010

TRAF-mediated TNFR-family signaling.

Curr Protoc Immunol 2009 Nov;Chapter 11:Unit11.9D

University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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November 2009

Adrm1 interacts with Atp6v0d2 and regulates osteoclast differentiation.

Biochem Biophys Res Commun 2009 Dec 8;390(3):585-90. Epub 2009 Oct 8.

Departments of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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December 2009

Promising bone-related therapeutic targets for rheumatoid arthritis.

Nat Rev Rheumatol 2009 Oct;5(10):543-8

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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October 2009

Enhancing CD8 T-cell memory by modulating fatty acid metabolism.

Nature 2009 Jul 3;460(7251):103-7. Epub 2009 Jun 3.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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July 2009

Immunomodulation by blockade of the TRANCE co-stimulatory pathway in murine allogeneic islet transplantation.

Transpl Int 2009 Sep 15;22(9):931-9. Epub 2009 May 15.

Cell Isolation and Transplantation Center, University of Geneva School of Medicine, Geneva, Switzerland.

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September 2009

Identification of LRRc17 as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation.

J Biol Chem 2009 May 31;284(22):15308-16. Epub 2009 Mar 31.

Department of Pathology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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May 2009

Selective inhibition of RANK blocks osteoclast maturation and function and prevents bone loss in mice.

J Clin Invest 2009 Apr 2;119(4):813-25. Epub 2009 Mar 2.

Division of Life and Pharmaceutical Sciences, Center for Cell Signaling and Drug Discovery Research, Department of Life Science, College of Natural Sciences, Ewha Womans University, Seoul, Republic of Korea.

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April 2009

Breaking into bone biology: target practice.

Nat Med 2009 Feb;15(2):144-5

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 421 Curie Boulevard, Philadelphia, Pennsylvania 19104, USA.

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February 2009

TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL.

PLoS One 2008 29;3(12):e4064. Epub 2008 Dec 29.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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March 2009

TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway.

J Biol Chem 2008 Dec 4;283(52):36211-20. Epub 2008 Nov 4.

Division of Molecular and Cellular Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.

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December 2008

Osteoimmunology: cytokines and the skeletal system.

BMB Rep 2008 Jul;41(7):495-510

The Department of Pathology and Laboratory Medicine, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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July 2008

Osteoimmunology: interactions of the bone and immune system.

Endocr Rev 2008 Jun 1;29(4):403-40. Epub 2008 May 1.

Department of Medicine, The University of Connecticut Health Center, N4054, MC5456, 263 Farmington Avenue, Farmington, Connecticut 06030-5456, USA.

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June 2008

TRAF-mediated TNFR-family signaling.

Curr Protoc Immunol 2002 Nov;Chapter 11:Unit 11.9D

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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November 2002

The tec family tyrosine kinase Btk Regulates RANKL-induced osteoclast maturation.

J Biol Chem 2008 Apr 14;283(17):11526-34. Epub 2008 Feb 14.

Department of Pathology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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April 2008

NHE10, an osteoclast-specific member of the Na+/H+ exchanger family, regulates osteoclast differentiation and survival [corrected].

Biochem Biophys Res Commun 2008 May 11;369(2):320-6. Epub 2008 Feb 11.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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May 2008

Cutting edge: requirement for TRAF6 in the induction of T cell anergy.

J Immunol 2008 Jan;180(1):34-8

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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January 2008

Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis.

Aging Cell 2008 Jan 20;7(1):23-31. Epub 2007 Nov 20.

Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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January 2008

The negative role of IdS in osteoclastogenesis.

Adv Exp Med Biol 2007 ;602:23-31

Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju, Korea.

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December 2007

Early embryonic lethality caused by targeted disruption of the TRAF-interacting protein (TRIP) gene.

Biochem Biophys Res Commun 2007 Nov 2;363(4):971-7. Epub 2007 Oct 2.

Department of Microbiology and BK21 BioBC, Chungnam National University, Daejeon 305-764, Republic of Korea.

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November 2007

NFATc1 induces osteoclast fusion via up-regulation of Atp6v0d2 and the dendritic cell-specific transmembrane protein (DC-STAMP).

Mol Endocrinol 2008 Jan 20;22(1):176-85. Epub 2007 Sep 20.

National Research Laboratory for Regulation of Bone Metabolism and Disease, Medical Research Center for Gene Regulation, Chonnam National University Medical School, Gwangju 501-746, Korea.

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January 2008

TRAF1 and its biological functions.

Adv Exp Med Biol 2007 ;597:25-31

Division of Molecular Life Sciences and Center for Cell Signaling Research, Ewha Womans University, Seoul, Korea.

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August 2007

Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

Nat Immunol 2007 Mar 4;8(3):304-11. Epub 2007 Feb 4.

Department of Immunology and Cell Biology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.

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March 2007

Vacuolar-type H+-ATPase-mediated acidosis promotes in vitro osteoclastogenesis via modulation of cell migration.

Int J Mol Med 2007 Mar;19(3):393-400

Department of Oral Biochemistry and Craniomaxillofacial Reconstructive Science, Seoul National University School of Dentistry, Seoul 110-749, Korea.

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March 2007

Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells.

Blood 2007 May 16;109(9):3706-12. Epub 2007 Jan 16.

Department of Medicine, Division of Hematology-Oncology, University of Pennsylvania School of Medicine, 3600 Spruce Street, Philadelphia, PA 19104, USA.

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May 2007

v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation.

Nat Med 2006 Dec 26;12(12):1403-9. Epub 2006 Nov 26.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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December 2006

The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation.

Immunity 2006 Nov 19;25(5):783-93. Epub 2006 Oct 19.

Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19010, USA.

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November 2006

T lymphocyte-deficient mice lose trabecular bone mass with ovariectomy.

J Bone Miner Res 2006 Nov;21(11):1704-12

Division of Endocrinology, Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut 06030-5456, USA.

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November 2006