Publications by authors named "Yong-Kook Kang"

51Publications

Dnmt1 binds and represses genomic retroelements via DNA methylation in mouse early embryos.

Nucleic Acids Res 2020 09;48(15):8431-8444

Development and Differentiation Research Center, Korea Research Institute of Bioscience Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, South Korea.

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http://dx.doi.org/10.1093/nar/gkaa584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470951PMC
September 2020

Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism.

Front Cell Dev Biol 2019 8;7:273. Epub 2019 Nov 8.

Development and Differentiation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, South Korea.

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http://dx.doi.org/10.3389/fcell.2019.00273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857330PMC
November 2019

Demethylation and derepression of genomic retroelements in the skeletal muscles of aged mice.

Aging Cell 2019 12 27;18(6):e13042. Epub 2019 Sep 27.

Development and Differentiation Research Center, Korea Research Institute of Bioscience Biotechnology (KRIBB), Daejeon, Korea.

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http://dx.doi.org/10.1111/acel.13042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826136PMC
December 2019

K120R mutation inactivates p53 by creating an aberrant splice site leading to nonsense-mediated mRNA decay.

Oncogene 2019 03 22;38(10):1597-1610. Epub 2018 Oct 22.

Division of Clinical Medicine, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea.

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http://www.nature.com/articles/s41388-018-0542-3
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http://dx.doi.org/10.1038/s41388-018-0542-3DOI Listing
March 2019

Surveillance of Retroelement Expression and Nucleic-Acid Immunity by Histone Methyltransferase SETDB1.

Authors:
Yong-Kook Kang

Bioessays 2018 09 13;40(9):e1800058. Epub 2018 Jun 13.

Development and Differentiation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Department of Functional Genomics, University of Science and Technology (UST), Yuseong-gu, Daejeon, 34141, South Korea.

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http://dx.doi.org/10.1002/bies.201800058DOI Listing
September 2018

Determination of Oocyte-Manipulation, Zygote-Manipulation, and Genome-Reprogramming Effects on the Transcriptomes of Bovine Blastocysts.

Front Genet 2018 24;9:143. Epub 2018 Apr 24.

Development and Differentiation Research Center, Korea Research Institute of Bioscience Biotechnology, Daejeon, South Korea.

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http://journal.frontiersin.org/article/10.3389/fgene.2018.00
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http://dx.doi.org/10.3389/fgene.2018.00143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928200PMC
April 2018

Age-associated bimodal transcriptional drift reduces intergenic disparities in transcription.

Aging (Albany NY) 2018 04;10(4):789-807

Development and Differentiation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Yuseong-gu, Daejeon 34141, South Korea.

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http://dx.doi.org/10.18632/aging.101428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940109PMC
April 2018

Simultaneous Methylation-Level Assessment of Hundreds of CpG Sites by Targeted Bisulfite PCR Sequencing (TBPseq).

Front Genet 2017 13;8:97. Epub 2017 Jul 13.

Development and Differentiation Research CenterKorea Research Institute of Bioscience & Biotechnology, Daejeon, South Korea.

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http://dx.doi.org/10.3389/fgene.2017.00097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507944PMC
July 2017

Characterization of X-Chromosome Gene Expression in Bovine Blastocysts Derived by Fertilization and Somatic Cell Nuclear Transfer.

Front Genet 2017 10;8:42. Epub 2017 Apr 10.

Development and Differentiation Research Center, Korea Research Institute of Bioscience BiotechnologyDaejeon, South Korea.

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http://dx.doi.org/10.3389/fgene.2017.00042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385346PMC
April 2017

Age-associated chromatin relaxation is enhanced in Huntington's disease mice.

Aging (Albany NY) 2017 03;9(3):803-822

Development and Differentiation Research Center, KRIBB, Yuseong-gu, Daejeon, 305-806, South Korea.

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http://dx.doi.org/10.18632/aging.101193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391233PMC
March 2017

The HIST1 Locus Escapes Reprogramming in Cloned Bovine Embryos.

G3 (Bethesda) 2016 05 3;6(5):1365-71. Epub 2016 May 3.

Development and Differentiation Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 305-806, South Korea Department of Functional Genomics, University of Science and Technology, Daejeon, 305-350, South Korea

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http://dx.doi.org/10.1534/g3.115.026666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856087PMC
May 2016

Transcriptomic Features of Bovine Blastocysts Derived by Somatic Cell Nuclear Transfer.

G3 (Bethesda) 2015 Sep 3;5(12):2527-38. Epub 2015 Sep 3.

Development and Differentiation Research Center, KRIBB, 125 Gwahak-ro, Yuseong-gu, Daejeon, 305-806, South Korea Department of Functional Genomics, University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon, 305-350, South Korea

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http://dx.doi.org/10.1534/g3.115.020016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683625PMC
September 2015

Rapid generation of secondary fibroblasts through teratoma formation.

Biotechniques 2015 Jul 1;59(1):34-41. Epub 2015 Jul 1.

Development and Differentiation Research Center, KRIBB, South Korea.

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http://dx.doi.org/10.2144/000114309DOI Listing
July 2015

SiNG-PCRseq: Accurate inter-sequence quantification achieved by spiking-in a neighbor genome for competitive PCR amplicon sequencing.

Sci Rep 2015 Jul 6;5:11879. Epub 2015 Jul 6.

Medical Research Division, Korea Institute of Oriental Medicine (KIOM), Daejeon 305-811, Korea.

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http://dx.doi.org/10.1038/srep11879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491706PMC
July 2015

Quantifying difference in gene expression profile between bovine blastocysts derived by in vitro fertilization and somatic cell nuclear transfer.

Gene Expr Patterns 2015 Sep-Nov;19(1-2):14-20. Epub 2015 Jun 21.

Development and Differentiation Research Center, KRIBB, 111 Gwahang-ro, Yuseong-gu, Daejeon 305-806, South Korea; Department of Functional Genomics, University of Science and Technology (UST), 113 Gwahang-ro, Yuseong-gu, 305-333 Daejeon, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.gep.2015.05.005DOI Listing
September 2016

An important role for peroxiredoxin II in survival of A549 lung cancer cells resistant to gefitinib.

Exp Mol Med 2015 May 29;47:e165. Epub 2015 May 29.

Disease Model Research Laboratory, Aging Intervention Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea.

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http://www.nature.com/articles/emm201524
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http://dx.doi.org/10.1038/emm.2015.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454996PMC
May 2015

Differences in the gene expression profiles of slow- and fast-forming preinduced pluripotent stem cell colonies.

Stem Cells Int 2015 7;2015:195928. Epub 2015 Apr 7.

Development and Differentiation Research Center, KRIBB, 111 Gwahak-ro, Yuseong-gu, Daejeon 305-806, Republic of Korea ; Department of Functional Genomics, University of Science and Technology (UST), 113 Gwahang-ro, Yuseong-gu, Daejeon 305-333, Republic of Korea.

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http://dx.doi.org/10.1155/2015/195928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405011PMC
May 2015

Assessment of difference in gene expression profile between embryos of different derivations.

Cell Reprogram 2015 Feb 30;17(1):49-58. Epub 2014 Dec 30.

1 Epigenetics Research Center , KRIBB, Daejeon, 305-806, Korea.

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http://dx.doi.org/10.1089/cell.2014.0057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312879PMC
February 2015

AGO2 and SETDB1 cooperate in promoter-targeted transcriptional silencing of the androgen receptor gene.

Nucleic Acids Res 2014 Dec 2;42(22):13545-56. Epub 2014 Sep 2.

Development and Differentiation Research Center, KRIBB, 111 Gwahangno, Yuseong-gu, Daejeon 305-806, South Korea Department of Functional Genomics, University of Science and Technology (UST), 113 Gwahangno, Yuseong-gu, 305-333 Daejeon, South Korea

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http://dx.doi.org/10.1093/nar/gku788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267665PMC
December 2014

SETDB1 in Early Embryos and Embryonic Stem Cells.

Authors:
Yong-Kook Kang

Curr Issues Mol Biol 2015 4;17:1-10. Epub 2014 Apr 4.

Development and Differentiation Research Center, KRIBB, 111 Gwahang-ro, Yuseong-gu, Daejeon 305-806, South Korea.

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June 2016

Regulated nuclear entry of over-expressed Setdb1.

Genes Cells 2013 Aug 20;18(8):694-703. Epub 2013 Jun 20.

Development and Differentiation Research Center, KRIBB, 111 Gwahangno, Yuseong-gu, Daejeon 305-806, South Korea.

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http://dx.doi.org/10.1111/gtc.12068DOI Listing
August 2013

Identifying MicroRNA and mRNA expression profiles in embryonic stem cells derived from parthenogenetic, androgenetic and fertilized blastocysts.

J Genet Genomics 2013 Apr 21;40(4):189-200. Epub 2013 Mar 21.

Department of Animal Science, Chungbuk National University, Gaeshin-dong, Cheongju, Chungbuk 361-763, South Korea.

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http://dx.doi.org/10.1016/j.jgg.2013.03.006DOI Listing
April 2013

Cardioprotective molecules are enriched in beating cardiomyocytes derived from human embryonic stem cells.

Int J Cardiol 2013 May 13;165(2):341-54. Epub 2012 Nov 13.

Department of Oral Pharmacology, School of Dentistry and Institute of Oral Bioscience, BK21 Project, Chonbuk National University, Jeonju, Republic of Korea.

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http://dx.doi.org/10.1016/j.ijcard.2012.07.013DOI Listing
May 2013

Involvement of microRNA-335-5p in cytoskeleton dynamics in mouse oocytes.

Reprod Fertil Dev 2013 ;25(4):691-9

Department of Animal Sciences, Chungbuk National University, Cheongju 361-763, Korea.

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http://www.publish.csiro.au/?paper=RD12138
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http://dx.doi.org/10.1071/RD12138DOI Listing
November 2013

Dynamics of Setdb1 expression in early mouse development.

Gene Expr Patterns 2012 May-Jun;12(5-6):213-8. Epub 2012 Apr 5.

Development and Differentiation Research Center, KRIBB, 111 Gwahangno, Yuseong-gu, Daejeon 305-806, South Korea.

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http://dx.doi.org/10.1016/j.gep.2012.03.005DOI Listing
August 2012

Dual functions of histone-lysine N-methyltransferase Setdb1 protein at promyelocytic leukemia-nuclear body (PML-NB): maintaining PML-NB structure and regulating the expression of its associated genes.

J Biol Chem 2011 Nov 14;286(47):41115-24. Epub 2011 Sep 14.

Development and Differentiation Research Center, Korea Research Institute of Bioscience and Biotechnology, University of Science and Technology, 113 Gwahangno, Yuseong-gu, 305-806 Daejeon, South Korea.

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http://dx.doi.org/10.1074/jbc.M111.248534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220519PMC
November 2011

Reprogramming fibroblasts into induced pluripotent stem cells with Bmi1.

Cell Res 2011 Sep 28;21(9):1305-15. Epub 2011 Jun 28.

Laboratory of Cell Function Regulation, College of Life Sciences and Biotechnology, Korea University, Seoul 136-701, Republic of Korea.

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http://dx.doi.org/10.1038/cr.2011.107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193470PMC
September 2011

JHDM3A module as an effector molecule in guide-directed modification of target chromatin.

J Biol Chem 2011 Feb 10;286(6):4461-70. Epub 2010 Dec 10.

Development and Differentiation Research Center, KRIBB, 111 Gwahangno, Yuseong-gu, Daejeon 305-806, South Korea.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M110.176040
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http://dx.doi.org/10.1074/jbc.M110.176040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039326PMC
February 2011

Active loss of DNA methylation in two-cell stage goat embryos.

Int J Dev Biol 2010 ;54(8-9):1323-8

Development and Differentiation Research Center, KRIBB, Daejon, South Korea.

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http://dx.doi.org/10.1387/ijdb.092973jpDOI Listing
March 2011

Phosphorylation of serine-10 of histone H3 shields modified lysine-9 selectively during mitosis.

Genes Cells 2010 Mar 13;15(3):181-92. Epub 2010 Jan 13.

Development and Differentiation Research Center, KRIBB, 111 Gwahangno, Yuseong-gu, Daejeon 305-806, KoreaDivision of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Korea.

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http://dx.doi.org/10.1111/j.1365-2443.2009.01375.xDOI Listing
March 2010

Cytoplasmic localization of oocyte-specific variant of porcine DNA methyltransferase-1 during early development.

Dev Dyn 2009 Jul;238(7):1666-73

Development and Differentiation Research Center, KRIBB, Yuseong-gu, Daejeon, Korea.

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http://dx.doi.org/10.1002/dvdy.21975DOI Listing
July 2009

Cytoskeleton-associated proteins are enriched in human embryonic-stem cell-derived neuroectodermal spheres.

Proteomics 2009 Mar;9(5):1128-41

Development and Differentiation Research Center, KRIBB, Yuseong-gu, Daejeon, South Korea.

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http://dx.doi.org/10.1002/pmic.200800234DOI Listing
March 2009

Expression profiles of protein tyrosine kinase genes in human embryonic stem cells.

Reproduction 2008 Oct 26;136(4):423-32. Epub 2008 Jun 26.

Korea Research Institute of Bioscience and Biotechnology (KRIBB), Center for Regenerative Medicine, Yuseong-Gu, Daejeon 305-806, South Korea.

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http://dx.doi.org/10.1530/REP-08-0080DOI Listing
October 2008

dSETDB1 and SU(VAR)3-9 sequentially function during germline-stem cell differentiation in Drosophila melanogaster.

PLoS One 2008 May 21;3(5):e2234. Epub 2008 May 21.

Center for Regenerative Medicine, Korean Research Institute of Bioscience and Biotechnology, Daejeon, Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002234PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377335PMC
May 2008

DNA methylation state is preserved in the sperm-derived pronucleus of the pig zygote.

Int J Dev Biol 2007 ;51(8):707-14

Center for Regenerative Medicine, KRIBB, 52 Oun-dong, Yuseong-gu, Daejon, South Korea.

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http://dx.doi.org/10.1387/ijdb.072450yjDOI Listing
January 2008

Dynamic DNA methylation reprogramming: active demethylation and immediate remethylation in the male pronucleus of bovine zygotes.

Dev Dyn 2007 Sep;236(9):2523-33

Center for Development and Differentiation, KRIBB, Daejon, South Korea.

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http://dx.doi.org/10.1002/dvdy.21278DOI Listing
September 2007

Characterization of DNA methylation change in stem cell marker genes during differentiation of human embryonic stem cells.

Biochem Biophys Res Commun 2007 Aug 25;359(3):536-42. Epub 2007 May 25.

Center for Regenerative Medicine, KRIBB, Eoeun-Dong, Yuseong-Gu, Daejeon 305-333, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2007.05.120DOI Listing
August 2007

Gradual development of a genome-wide H3-K9 trimethylation pattern in paternally derived pig pronucleus.

Dev Dyn 2007 Jun;236(6):1509-16

Center for Development and Differentiation, KRIBB, Yuseong-gu, Daejon, South Korea.

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http://dx.doi.org/10.1002/dvdy.21150DOI Listing
June 2007

Analysis of DNA methylation profiles in preimplantation embryos using bisulfite mutagenesis.

Methods Mol Biol 2006 ;325:251-60

Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology, Daejeon.

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http://dx.doi.org/10.1385/1-59745-005-7:251DOI Listing
July 2006

Methylation changes of lysine 9 of histone H3 during preimplantation mouse development.

Mol Cells 2005 Dec;20(3):423-8

Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-333, Korea.

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December 2005

Inheritable histone H4 acetylation of somatic chromatins in cloned embryos.

J Biol Chem 2006 Mar 21;281(9):6048-57. Epub 2005 Dec 21.

Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 52 Eoeun-dong, Yuseong, Daejeon 305-806, Korea.

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http://dx.doi.org/10.1074/jbc.M511340200DOI Listing
March 2006

Varied patterns of DNA methylation change between different satellite regions in bovine preimplantation development.

Mol Reprod Dev 2005 May;71(1):29-35

Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Yuseong, Daejeon, Korea.

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http://dx.doi.org/10.1002/mrd.20249DOI Listing
May 2005

Differential DNA methylation reprogramming of various repetitive sequences in mouse preimplantation embryos.

Biochem Biophys Res Commun 2004 Nov;324(1):58-63

Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology (KRIBB), P.O. Box 115, Yuseong, Daejeon 305-600, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2004.09.023DOI Listing
November 2004

A paucity of structural integrity in cloned porcine blastocysts produced in vitro.

Theriogenology 2004 Sep;62(5):779-89

Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology, 52 Eoeun-dong, Yuseong, Daejeon 305-806, Republic of Korea.

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http://dx.doi.org/10.1016/j.theriogenology.2003.12.027DOI Listing
September 2004

Histone H3-K9 methyltransferase ESET is essential for early development.

Mol Cell Biol 2004 Mar;24(6):2478-86

Cutaneous Biology Research Center and Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://mcb.asm.org/content/24/6/2478.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC355869PMC
http://dx.doi.org/10.1128/mcb.24.6.2478-2486.2004DOI Listing
March 2004

Precise recapitulation of methylation change in early cloned embryos.

Mol Reprod Dev 2003 Sep;66(1):32-7

Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology, Daejeon, South Korea.

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http://dx.doi.org/10.1002/mrd.10330DOI Listing
September 2003

Reprogramming DNA methylation in the preimplantation stage: peeping with Dolly's eyes.

Curr Opin Cell Biol 2003 Jun;15(3):290-5

Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology, Oun-dong 52, Yusong, 305-333, Daejeon, Korea.

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http://dx.doi.org/10.1016/s0955-0674(03)00031-0DOI Listing
June 2003

Aberrant allocations of inner cell mass and trophectoderm cells in bovine nuclear transfer blastocysts.

Biol Reprod 2002 Aug;67(2):487-92

Animal Developmental Biotechnology Laboratory, Korea Research Institute of Bioscience and Biotechnology, Yusong, Daejeon 305-600, Korea.

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http://dx.doi.org/10.1095/biolreprod67.2.487DOI Listing
August 2002

Limited demethylation leaves mosaic-type methylation states in cloned bovine pre-implantation embryos.

EMBO J 2002 Mar;21(5):1092-100

Animal Developmental Biotechnology Laboratory, Korea Research Institute of Bioscience and Biotechnology, PO Box 115, Yusong, Taejon 305-600, South Korea.

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http://emboj.embopress.org/cgi/doi/10.1093/emboj/21.5.1092
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http://dx.doi.org/10.1093/emboj/21.5.1092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125883PMC
March 2002