Yong-Jie Lu

Yong-Jie Lu

UNVERIFIED PROFILE

Are you Yong-Jie Lu?   Register this Author

Register author
Yong-Jie Lu

Yong-Jie Lu

Publications by authors named "Yong-Jie Lu"

Are you Yong-Jie Lu?   Register this Author

73Publications

2250Reads

31Profile Views

Bladder cancer, a unique model to understand cancer immunity and develop immunotherapy approaches.

J Pathol 2019 May 18. Epub 2019 May 18.

Department of Urology, The First Affiliated Hospital and Academy of Medical Sciences, Zhengzhou University, Zhengzhou, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/path.5306DOI Listing
May 2019

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.

Authors:
Fredrick R Schumacher Ali Amin Al Olama Sonja I Berndt Sara Benlloch Mahbubl Ahmed Edward J Saunders Tokhir Dadaev Daniel Leongamornlert Ezequiel Anokian Clara Cieza-Borrella Chee Goh Mark N Brook Xin Sheng Laura Fachal Joe Dennis Jonathan Tyrer Kenneth Muir Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis J Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail P Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Håkansson Catharine M L West Alison M Dunning Neil Burnet Lorelei A Mucci Edward Giovannucci Gerald L Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry S Rosenstein Sarah L Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weischer Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Sandeep Singhal Chavdar Slavov Vanio Mitev Matthew Parliament Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Zuxi Cui Peter Kraft Christopher I Amos David V Conti Douglas F Easton Fredrik Wiklund Stephen J Chanock Brian E Henderson Zsofia Kote-Jarai Christopher A Haiman Rosalind A Eeles

Nat Genet 2019 02;51(2):363

Institute of Cancer Research, London, UK.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41588-018-0330-6
Publisher Site
http://dx.doi.org/10.1038/s41588-018-0330-6DOI Listing
February 2019

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study.

Cancer Epidemiol Biomarkers Prev 2019 Jan 23;28(1):208-216. Epub 2018 Oct 23.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.

View Article

Download full-text PDF

Source
http://cebp.aacrjournals.org/lookup/doi/10.1158/1055-9965.EP
Publisher Site
http://dx.doi.org/10.1158/1055-9965.EPI-18-0079DOI Listing
January 2019

Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry.

Nat Commun 2019 01 17;10(1):382. Epub 2019 Jan 17.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, CA, 90033, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-08293-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336778PMC
January 2019

PIK3CA copy number aberration and activation of the PI3K-AKT-mTOR pathway in varied disease states of penile cancer.

PLoS One 2018 14;13(6):e0198905. Epub 2018 Jun 14.

Barts Cancer Institute, Centre for Molecular Oncology, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198905PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002057PMC
December 2018

Germline variation at 8q24 and prostate cancer risk in men of European ancestry.

Nat Commun 2018 11 5;9(1):4616. Epub 2018 Nov 5.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, CA, 90033, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41467-018-06863-1
Publisher Site
http://dx.doi.org/10.1038/s41467-018-06863-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218483PMC
November 2018

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.

Authors:
Fredrick R Schumacher Ali Amin Al Olama Sonja I Berndt Sara Benlloch Mahbubl Ahmed Edward J Saunders Tokhir Dadaev Daniel Leongamornlert Ezequiel Anokian Clara Cieza-Borrella Chee Goh Mark N Brook Xin Sheng Laura Fachal Joe Dennis Jonathan Tyrer Kenneth Muir Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis J Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail P Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Håkansson Catharine M L West Alison M Dunning Neil Burnet Lorelei A Mucci Edward Giovannucci Gerald L Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry S Rosenstein Sarah L Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weischer Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Sandeep Singhal Chavdar Slavov Vanio Mitev Matthew Parliament Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Zuxi Cui Peter Kraft Christopher I Amos David V Conti Douglas F Easton Fredrik Wiklund Stephen J Chanock Brian E Henderson Zsofia Kote-Jarai Christopher A Haiman Rosalind A Eeles

Nat Genet 2018 07 11;50(7):928-936. Epub 2018 Jun 11.

Institute of Cancer Research, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-018-0142-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568012PMC
July 2018

The Prognostic Value of PIK3CA Copy Number Gain in Penile Cancer.

Urology 2018 Jul 19. Epub 2018 Jul 19.

Barts Cancer Institute, Centre for Molecular Oncology, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urology.2018.03.056DOI Listing
July 2018

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

Authors:
Tokhir Dadaev Edward J Saunders Paul J Newcombe Ezequiel Anokian Daniel A Leongamornlert Mark N Brook Clara Cieza-Borrella Martina Mijuskovic Sarah Wakerell Ali Amin Al Olama Fredrick R Schumacher Sonja I Berndt Sara Benlloch Mahbubl Ahmed Chee Goh Xin Sheng Zhuo Zhang Kenneth Muir Koveela Govindasami Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Hakansson Catharine West Alison M Dunning Neil Burnet Lorelei Mucci Edward Giovannucci Gerald Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry Rosenstein Sarah Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Laura Fachal Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weisher Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Chavdar Slavov Vanio Mitev Matthew Parliament Sandeep Singhal Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Andrzej Kierzek Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Peter Kraft Matthew Freedman Fredrik Wiklund Stephen Chanock Brian E Henderson Douglas F Easton Christopher A Haiman Rosalind A Eeles David V Conti Zsofia Kote-Jarai

Nat Commun 2018 06 11;9(1):2256. Epub 2018 Jun 11.

The Institute of Cancer Research, London, SW7 3RP, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-04109-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995836PMC
June 2018

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.

Nat Genet 2018 05 16;50(5):682-692. Epub 2018 Apr 16.

The Institute of Cancer Research, London, UK.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41588-018-0086-z
Publisher Site
http://dx.doi.org/10.1038/s41588-018-0086-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372064PMC
May 2018

Analysis of the PI3K-AKT-mTOR pathway in penile cancer: evaluation of a therapeutically targetable pathway.

Oncotarget 2018 Mar 23;9(22):16074-16086. Epub 2018 Mar 23.

Centre for Molecular Oncology, Bart's Cancer Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://www.oncotarget.com/fulltext/24688
Publisher Site
http://dx.doi.org/10.18632/oncotarget.24688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882318PMC
March 2018

The Novel Association of Circulating Tumor Cells and Circulating Megakaryocytes with Prostate Cancer Prognosis.

Clin Cancer Res 2017 Sep 14;23(17):5112-5122. Epub 2017 Jun 14.

Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-16-3081DOI Listing
September 2017

Postchemotherapy changes in testicular germ cell tumours: biology and morphology.

Histopathology 2017 Jan;70(1):26-39

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine and Indiana Pathology Institute, Indianapolis, IN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/his.13078DOI Listing
January 2017

NKAIN2 functions as a novel tumor suppressor in prostate cancer.

Oncotarget 2016 Sep;7(39):63793-63803

Centre for Molecular Oncology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.11690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325404PMC
September 2016

The structure and function of NKAIN2-a candidate tumor suppressor.

Int J Clin Exp Med 2015 15;8(10):17072-9. Epub 2015 Oct 15.

Molecular Oncology, Barts Cancer Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London London, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694199PMC
January 2016

High frequency of the SDK1:AMACR fusion transcript in Chinese prostate cancer.

Int J Clin Exp Med 2015 15;8(9):15127-36. Epub 2015 Sep 15.

Department of Pathology, The First Affiliated Hospital, Zhejiang University Medical College Hangzhou, China.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658885PMC
December 2015

Protein S-palmitoylation and cancer.

Biochim Biophys Acta 2015 Aug 22;1856(1):107-20. Epub 2015 Jun 22.

Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbcan.2015.06.004DOI Listing
August 2015

Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci.

Cancer Epidemiol Biomarkers Prev 2015 Jul 2;24(7):1121-9. Epub 2015 Apr 2.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1055-9965.EPI-14-0317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491026PMC
July 2015

Gonorrhea and Prostate Cancer Incidence: An Updated Meta-Analysis of 21 Epidemiologic Studies.

Med Sci Monit 2015 Jul 1;21:1902-10. Epub 2015 Jul 1.

Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China (mainland).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12659/MSM.893579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502545PMC
July 2015

AGE/RAGE/Akt pathway contributes to prostate cancer cell proliferation by promoting Rb phosphorylation and degradation.

Am J Cancer Res 2015 15;5(5):1741-50. Epub 2015 Apr 15.

Key Laboratory of Proteomics of Guangdong Province and Key Laboratory of Transcriptomics and Proteomics of Human Diseases Supported by The Ministry of Education of China, Southern Medical University Guangzhou 510515, China.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497440PMC
July 2015

DNA replication-dependent induction of gene proximity by androgen.

Hum Mol Genet 2015 Feb 3;24(4):963-71. Epub 2014 Oct 3.

Centre for Molecular Oncology,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddu508DOI Listing
February 2015

Involvement of different mechanisms for the association of CAG repeat length polymorphism in androgen receptor gene with prostate cancer.

Am J Cancer Res 2014 19;4(6):886-96. Epub 2014 Nov 19.

Centre for Molecular Oncology, Barts Cancer Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London London, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266720PMC
December 2014

Transcription-mediated chimeric RNAs in prostate cancer: time to revisit old hypothesis?

OMICS 2014 Oct 4;18(10):615-24. Epub 2014 Sep 4.

1 Department of Pathology, The First Affiliated Hospital, Zhejiang University Medical College , Hangzhou, China .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/omi.2014.0042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175977PMC
October 2014

Co-expression of RAGE and HMGB1 is associated with cancer progression and poor patient outcome of prostate cancer.

Am J Cancer Res 2014 16;4(4):369-77. Epub 2014 Jul 16.

Department of Urology and Medical Center for Overseas Patients, Nanfang Hospital, Southern Medical University Guangzhou, China.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106654PMC
July 2014

Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging.

Cancer Res 2014 Feb 27;74(3):896-907. Epub 2013 Nov 27.

Authors' Affiliations: Barts Cancer Institute-a Cancer Research UK Center of Excellence, John Vane Science Center, Queen Mary University of London; Department of Medicine, Imperial College, Charing Cross Campus; St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London; Wellcome Trust Center for Human Genetics, Oxford; Cancer Research UK Cambridge Research Institute, Li Ka Shing Center; Hutchison/MRC Research Center, University of Cambridge, Medical Research Council Cancer Unit; Pharmacometrics Ltd., Cambridge; Dundee Cancer Center, University of Dundee, Ninewells Hospital, Dundee, United Kingdom; Laboratory of Cancer Genetics and Translational Oncology, S Croce General Hospital, Cuneo, Italy; Department of Structural Biology, Medical University of Lodz, Lodz, Poland; Polaris Group, San Diego, California; Department of Pathology, Chi-Mei Medical Center; Department of Biotechnology, Southern Taiwan University of Science and Technology, Tainan, Taiwan; and National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-13-1702DOI Listing
February 2014

The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer.

Clin Cancer Res 2013 Dec 15;19(24):6924-34. Epub 2013 Oct 15.

Authors' Affiliations: Barts Cancer Institute, Queen Mary University of London; Experimental Cancer Medicine Centre, University College; The Institute of Cancer Research; Guys and St Thomas' Hospital; The Royal Free Hospital London, London; Edinburgh Urological Cancer Group, University of Edinburgh, Edinburgh; Astra Zeneca, Manchester; School of Medicine, University of St Andrews, Fife, United Kingdom; National Cancer Institute, Amsterdam, the Netherlands; and University of Ghent, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-1631DOI Listing
December 2013

Ethnical disparities of prostate cancer predisposition: genetic polymorphisms in androgen-related genes.

Am J Cancer Res 2013 3;3(2):127-51. Epub 2013 Apr 3.

Department of Urology, the First Affiliated Hospital of Chongqing Medical University China ; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, Barts and The London School of Medicine and Dentistry London UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623834PMC
April 2013

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.

Authors:
Ali Amin Al Olama Zsofia Kote-Jarai Fredrick R Schumacher Fredrik Wiklund Sonja I Berndt Sara Benlloch Graham G Giles Gianluca Severi David E Neal Freddie C Hamdy Jenny L Donovan David J Hunter Brian E Henderson Michael J Thun Michael Gaziano Edward L Giovannucci Afshan Siddiq Ruth C Travis David G Cox Federico Canzian Elio Riboli Timothy J Key Gerald Andriole Demetrius Albanes Richard B Hayes Johanna Schleutker Anssi Auvinen Teuvo L J Tammela Maren Weischer Janet L Stanford Elaine A Ostrander Cezary Cybulski Jan Lubinski Stephen N Thibodeau Daniel J Schaid Karina D Sorensen Jyotsna Batra Judith A Clements Suzanne Chambers Joanne Aitken Robert A Gardiner Christiane Maier Walther Vogel Thilo Dörk Hermann Brenner Tomonori Habuchi Sue Ingles Esther M John Joanne L Dickinson Lisa Cannon-Albright Manuel R Teixeira Radka Kaneva Hong-Wei Zhang Yong-Jie Lu Jong Y Park Kathleen A Cooney Kenneth R Muir Daniel A Leongamornlert Edward Saunders Malgorzata Tymrakiewicz Nadiya Mahmud Michelle Guy Koveela Govindasami Lynne T O'Brien Rosemary A Wilkinson Amanda L Hall Emma J Sawyer Tokhir Dadaev Jonathan Morrison David P Dearnaley Alan Horwich Robert A Huddart Vincent S Khoo Christopher C Parker Nicholas Van As Christopher J Woodhouse Alan Thompson Tim Dudderidge Chris Ogden Colin S Cooper Artitaya Lophatonanon Melissa C Southey John L Hopper Dallas English Jarmo Virtamo Loic Le Marchand Daniele Campa Rudolf Kaaks Sara Lindstrom W Ryan Diver Susan Gapstur Meredith Yeager Angela Cox Mariana C Stern Roman Corral Markus Aly William Isaacs Jan Adolfsson Jianfeng Xu S Lilly Zheng Tiina Wahlfors Kimmo Taari Paula Kujala Peter Klarskov Børge G Nordestgaard M Andreas Røder Ruth Frikke-Schmidt Stig E Bojesen Liesel M FitzGerald Suzanne Kolb Erika M Kwon Danielle M Karyadi Torben Falck Orntoft Michael Borre Antje Rinckleb Manuel Luedeke Kathleen Herkommer Andreas Meyer Jürgen Serth James R Marthick Briony Patterson Dominika Wokolorczyk Amanda Spurdle Felicity Lose Shannon K McDonnell Amit D Joshi Ahva Shahabi Pedro Pinto Joana Santos Ana Ray Thomas A Sellers Hui-Yi Lin Robert A Stephenson Craig Teerlink Heiko Muller Dietrich Rothenbacher Norihiko Tsuchiya Shintaro Narita Guang-Wen Cao Chavdar Slavov Vanio Mitev Stephen Chanock Henrik Gronberg Christopher A Haiman Peter Kraft Douglas F Easton Rosalind A Eeles

Hum Mol Genet 2013 Jan 12;22(2):408-15. Epub 2012 Oct 12.

Strangeways Laboratory, Centre for Cancer Genetic Epidemiology, Worts Causeway, Cambridge CB1 8RN, UK.

View Article

Download full-text PDF

Source
http://hmg.oxfordjournals.org/content/22/2/408.full.pdf
Web Search
http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/dds425
Publisher Site
http://dx.doi.org/10.1093/hmg/dds425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526158PMC
January 2013

Chinese and Western prostate cancers show alternate pathogenetic pathways in association with ERG status.

Am J Cancer Res 2012 20;2(6):736-44. Epub 2012 Nov 20.

Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London UK ; Department of Pathology, Cancer Hospital (Institute), Peking Union Medical College, Chinese Academy of Medical Sciences Beijing, China.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512186PMC
December 2012

Identification of frequent BRAF copy number gain and alterations of RAF genes in Chinese prostate cancer.

Genes Chromosomes Cancer 2012 Nov 25;51(11):1014-23. Epub 2012 Jul 25.

Department of Pathology, The First Affiliated Hospital, Zhejiang University Medical College, Hangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.21984DOI Listing
November 2012

The complexity of prostate cancer: genomic alterations and heterogeneity.

Nat Rev Urol 2012 Nov;9(11):652-64

Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, John Vane Science Centre, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrurol.2012.185DOI Listing
November 2012

High-resolution genome-wide copy-number analysis suggests a monoclonal origin of multifocal prostate cancer.

Genes Chromosomes Cancer 2012 Jun 15;51(6):579-89. Epub 2012 Feb 15.

Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.21944DOI Listing
June 2012

Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing.

Dis Markers 2011 ;30(4):151-61

Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Barts & the London School of Dentistry and Medicine, Queen Mary University of London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/DMA-2011-0790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825083PMC
September 2011

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study.

Authors:
Zsofia Kote-Jarai Ali Amin Al Olama Graham G Giles Gianluca Severi Johanna Schleutker Maren Weischer Daniele Campa Elio Riboli Tim Key Henrik Gronberg David J Hunter Peter Kraft Michael J Thun Sue Ingles Stephen Chanock Demetrius Albanes Richard B Hayes David E Neal Freddie C Hamdy Jenny L Donovan Paul Pharoah Fredrick Schumacher Brian E Henderson Janet L Stanford Elaine A Ostrander Karina Dalsgaard Sorensen Thilo Dörk Gerald Andriole Joanne L Dickinson Cezary Cybulski Jan Lubinski Amanda Spurdle Judith A Clements Suzanne Chambers Joanne Aitken R A Frank Gardiner Stephen N Thibodeau Dan Schaid Esther M John Christiane Maier Walther Vogel Kathleen A Cooney Jong Y Park Lisa Cannon-Albright Hermann Brenner Tomonori Habuchi Hong-Wei Zhang Yong-Jie Lu Radka Kaneva Ken Muir Sara Benlloch Daniel A Leongamornlert Edward J Saunders Malgorzata Tymrakiewicz Nadiya Mahmud Michelle Guy Lynne T O'Brien Rosemary A Wilkinson Amanda L Hall Emma J Sawyer Tokhir Dadaev Jonathan Morrison David P Dearnaley Alan Horwich Robert A Huddart Vincent S Khoo Christopher C Parker Nicholas Van As Christopher J Woodhouse Alan Thompson Tim Christmas Chris Ogden Colin S Cooper Aritaya Lophatonanon Melissa C Southey John L Hopper Dallas R English Tiina Wahlfors Teuvo L J Tammela Peter Klarskov Børge G Nordestgaard M Andreas Røder Anne Tybjærg-Hansen Stig E Bojesen Ruth Travis Federico Canzian Rudolf Kaaks Fredrik Wiklund Markus Aly Sara Lindstrom W Ryan Diver Susan Gapstur Mariana C Stern Roman Corral Jarmo Virtamo Angela Cox Christopher A Haiman Loic Le Marchand Liesel Fitzgerald Suzanne Kolb Erika M Kwon Danielle M Karyadi Torben Falck Orntoft Michael Borre Andreas Meyer Jürgen Serth Meredith Yeager Sonja I Berndt James R Marthick Briony Patterson Dominika Wokolorczyk Jyotsna Batra Felicity Lose Shannon K McDonnell Amit D Joshi Ahva Shahabi Antje E Rinckleb Ana Ray Thomas A Sellers Hui-Yi Lin Robert A Stephenson James Farnham Heiko Muller Dietrich Rothenbacher Norihiko Tsuchiya Shintaro Narita Guang-Wen Cao Chavdar Slavov Vanio Mitev Douglas F Easton Rosalind A Eeles

Nat Genet 2011 Jul 10;43(8):785-91. Epub 2011 Jul 10.

The Institute of Cancer Research, Sutton, Surrey, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396006PMC
July 2011

Alternative HER/PTEN/Akt pathway activation in HPV positive and negative penile carcinomas.

PLoS One 2011 Mar 2;6(3):e17517. Epub 2011 Mar 2.

Centre for Molecular Oncology and Imaging, Institute of Cancer, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017517PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047574PMC
March 2011

Androgen-induced TMPRSS2:ERG fusion in nonmalignant prostate epithelial cells.

Cancer Res 2010 Dec 14;70(23):9544-8. Epub 2010 Oct 14.

Centre of Molecular Oncology & Imaging, Institute of Cancer, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-10-1638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000385PMC
December 2010

Distinct genomic alterations in prostate cancers in Chinese and Western populations suggest alternative pathways of prostate carcinogenesis.

Cancer Res 2010 Jul 1;70(13):5207-12. Epub 2010 Jun 1.

Molecular Oncology & Imaging Centre, Medical Oncology Centre, Institute of Cancer, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-09-4074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896548PMC
July 2010

The association of CCND1 overexpression and cisplatin resistance in testicular germ cell tumors and other cancers.

Am J Pathol 2010 Jun 15;176(6):2607-15. Epub 2010 Apr 15.

Medical Oncology Centre, Cancer Institute, Barts and London School of Medicine and Dentistry, Queen Mary, University of London, Charterhouse Square, London EC1M 6BQ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2353/ajpath.2010.090780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877824PMC
June 2010

The relative activity of cisplatin, oxaliplatin and satraplatin in testicular germ cell tumour sensitive and resistant cell lines.

Cancer Chemother Pharmacol 2009 Oct 5;64(5):925-33. Epub 2009 Mar 5.

Orchid Cancer Pharmacology Group, Centre for Experimental Cancer Medicine, Institute of Cancer, St Bartholomew's Hospital, West Smithfield, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00280-009-0944-6DOI Listing
October 2009

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.

Authors:
Rosalind A Eeles Zsofia Kote-Jarai Ali Amin Al Olama Graham G Giles Michelle Guy Gianluca Severi Kenneth Muir John L Hopper Brian E Henderson Christopher A Haiman Johanna Schleutker Freddie C Hamdy David E Neal Jenny L Donovan Janet L Stanford Elaine A Ostrander Sue A Ingles Esther M John Stephen N Thibodeau Daniel Schaid Jong Y Park Amanda Spurdle Judith Clements Joanne L Dickinson Christiane Maier Walther Vogel Thilo Dörk Timothy R Rebbeck Kathleen A Cooney Lisa Cannon-Albright Pierre O Chappuis Pierre Hutter Maurice Zeegers Radka Kaneva Hong-Wei Zhang Yong-Jie Lu William D Foulkes Dallas R English Daniel A Leongamornlert Malgorzata Tymrakiewicz Jonathan Morrison Audrey T Ardern-Jones Amanda L Hall Lynne T O'Brien Rosemary A Wilkinson Edward J Saunders Elizabeth C Page Emma J Sawyer Stephen M Edwards David P Dearnaley Alan Horwich Robert A Huddart Vincent S Khoo Christopher C Parker Nicholas Van As Christopher J Woodhouse Alan Thompson Tim Christmas Chris Ogden Colin S Cooper Melissa C Southey Artitaya Lophatananon Jo-Fen Liu Laurence N Kolonel Loic Le Marchand Tiina Wahlfors Teuvo L Tammela Anssi Auvinen Sarah J Lewis Angela Cox Liesel M FitzGerald Joseph S Koopmeiners Danielle M Karyadi Erika M Kwon Mariana C Stern Roman Corral Amit D Joshi Ahva Shahabi Shannon K McDonnell Thomas A Sellers Julio Pow-Sang Suzanne Chambers Joanne Aitken R A Frank Gardiner Jyotsna Batra Mary Anne Kedda Felicity Lose Andrea Polanowski Briony Patterson Jürgen Serth Andreas Meyer Manuel Luedeke Klara Stefflova Anna M Ray Ethan M Lange Jim Farnham Humera Khan Chavdar Slavov Atanaska Mitkova Guangwen Cao Douglas F Easton

Nat Genet 2009 Oct 20;41(10):1116-21. Epub 2009 Sep 20.

The Institute of Cancer Research, Sutton, Surrey, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846760PMC
October 2009

Metastatic potential of lung squamous cell carcinoma associated with HSPC300 through its interaction with WAVE2.

Lung Cancer 2009 Sep 2;65(3):299-305. Epub 2009 Jul 2.

State Key Laboratory of Molecular Oncology, Cancer Institute (Hospital), Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lungcan.2009.06.001DOI Listing
September 2009

Use of SNPs in cancer predisposition analysis, diagnosis and prognosis: tools and prospects.

Expert Opin Med Diagn 2009 May 8;3(3):313-26. Epub 2009 Apr 8.

Queen Mary University of London, Barts and the London School of Medicine and Dentistry, Institute of Cancer, Centre for Molecular Oncology and Imaging, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK +44 20 7882 6140 ; +44 20 7014 0431 ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/17530050902828325DOI Listing
May 2009

Subtle genomic alterations and genomic instability revealed in diploid cancer cell lines.

Cancer Lett 2008 Aug 14;267(1):49-54. Epub 2008 Apr 14.

Centre of Medical Oncology, Institute of Cancer, Barts and London School of Medicine and Dentistry, Queen Mary, University of London, Charterhouse Square, London EC1M 6BQ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2008.03.003DOI Listing
August 2008

Identification of genomic changes associated with cisplatin resistance in testicular germ cell tumor cell lines.

Genes Chromosomes Cancer 2008 Jul;47(7):604-13

Medical Oncology Centre, Institute of Cancer, Barts and London School of Medicine and Dentistry, Queen Mary, University of London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.20564DOI Listing
July 2008

Detection of TMPRSS2:ERG fusion gene in circulating prostate cancer cells.

Asian J Androl 2008 May;10(3):467-73

Medical Oncology Centre, Cancer Institute, Department of Histopathology and Morbid Anatomy, Barts and London School of Medicine and Dentistry, Queen Mary, University of London, Charterhouse Square, London EC1M 6BQ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1745-7262.2008.00401.xDOI Listing
May 2008

Rapid high-resolution karyotyping with precise identification of chromosome breakpoints.

Genes Chromosomes Cancer 2007 Jul;46(7):675-83

Medical Oncology Center, Cancer Institute, Barts and London School of Medicine and Dentistry, Queen Mary, University of London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.20452DOI Listing
July 2007

The pattern of genomic gains in salivary gland MALT lymphomas.

Haematologica 2007 Jul;92(7):921-7

Division of Molecular Histopathology, Department of Pathology University of Cambridge, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.10191DOI Listing
July 2007

The application of single nucleotide polymorphism microarrays in cancer research.

Curr Genomics 2007 Jun;8(4):219-28

Medical Oncology Centre, Cancer Institute, Barts and London School of Medicine and Dentistry, Queen Mary, University of London, Charterhouse Square, London, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430687PMC
June 2007

Identification of a recurrent t(4;6) chromosomal translocation in prostate cancer.

J Urol 2007 May;177(5):1907-12

Department of Medical Oncology, St. Bartholomew's Hospital, Queen Mary Wesfield School of Medicine, Queen Mary University, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.juro.2007.01.001DOI Listing
May 2007

Role for amplification and expression of glypican-5 in rhabdomyosarcoma.

Cancer Res 2007 Jan;67(1):57-65

Molecular Cytogenetics Team, Paediatric Oncology, Cancer Research UK Centre for Cancer Therapeutics, The Institute of Cancer Research, Sutton, Surrey, United Kingdom.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-06-1650DOI Listing
January 2007

Nascent pre-rRNA overexpression correlates with an adverse prognosis in alveolar rhabdomyosarcoma.

Genes Chromosomes Cancer 2006 Sep;45(9):839-45

Molecular Cytogenetics, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.20347DOI Listing
September 2006

Overexpression of genes on 16q associated with cisplatin resistance of testicular germ cell tumor cell lines.

Genes Chromosomes Cancer 2005 Jun;43(2):211-6

Department of Medical Oncology, Barts and London School of Medicine and Dentistry, Queen Mary, University of London, Charterhouse Square, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.20173DOI Listing
June 2005

A combination of molecular cytogenetic analyses reveals complex genetic alterations in conventional renal cell carcinoma.

Cancer Genet Cytogenet 2005 May;159(1):1-9

Cancer Research UK Medical Oncology Unit, Queen Mary University of London, Charterhouse Square, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cancergencyto.2004.09.020DOI Listing
May 2005

Expression profiling targeting chromosomes for tumor classification and prediction of clinical behavior.

Genes Chromosomes Cancer 2003 Nov;38(3):207-14

Molecular Cytogenetics, Section of Molecular Carcinogenesis, Institute of Cancer Research, Sutton, Surrey, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.10276DOI Listing
November 2003

Loss of 13q14-q21 and gain of 5p14-pter in the progression of leiomyosarcoma.

Mod Pathol 2003 Aug;16(8):778-85

Molecular Cytogenetics, Section of Molecular Carcinogenesis, Institute of Cancer Research, Sutton, Surrey, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.MP.0000083648.45923.2BDOI Listing
August 2003

Chromosome 1q expression profiling and relapse in Wilms' tumour.

Lancet 2002 Aug;360(9330):385-6

Section of Paediatrics, Institute of Cancer Research and Royal Marsden Hospital NHS Trust, Sutton, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(02)09596-XDOI Listing
August 2002

Hypothesis: a novel route for immortalization of epithelial cells by Epstein-Barr virus.

Oncogene 2002 Jan;21(5):825-35

Viral Oncology Unit, Department of Medicine, Imperial College of Science, Technology and Medicine, Norfolk Place, London W2 1PG, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.onc.1205130DOI Listing
January 2002