Yon Rojanasakul

Yon Rojanasakul

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Yon Rojanasakul

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The SOX9-Aldehyde Dehydrogenase Axis Determines Resistance to Chemotherapy in Non-Small-Cell Lung Cancer.

Mol Cell Biol 2020 Jan 3;40(2). Epub 2020 Jan 3.

West Virginia University Cancer Institute, West Virginia University, Morgantown, West Virginia, USA

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http://dx.doi.org/10.1128/MCB.00307-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944474PMC
January 2020

Iron Oxide Nanoparticle-Induced Neoplastic-Like Cell Transformation Is Reduced with a Protective Amorphous Silica Coating.

Chem Res Toxicol 2019 Dec 11;32(12):2382-2397. Epub 2019 Nov 11.

Department of Pharmaceutical and Pharmacological Sciences, School of Pharmacy , West Virginia University , Morgantown , West Virginia 26506 , United States.

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http://dx.doi.org/10.1021/acs.chemrestox.9b00118DOI Listing
December 2019

Impacts of Organomodified Nanoclays and Their Incinerated Byproducts on Bronchial Cell Monolayer Integrity.

Chem Res Toxicol 2019 Dec 19;32(12):2445-2458. Epub 2019 Nov 19.

Health Effects Laboratory Division , National Institute for Occupational Safety and Health , Morgantown , West Virginia 26505 , United States.

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http://dx.doi.org/10.1021/acs.chemrestox.9b00277DOI Listing
December 2019

Toxicity screening of two prevalent metal organic frameworks for therapeutic use in human lung epithelial cells.

Int J Nanomedicine 2019 17;14:7583-7591. Epub 2019 Sep 17.

Department of Chemical and Biomedical Engineering, Benjamin M. Statler College of Engineering and Mineral Resources, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.2147/IJN.S215950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756165PMC
November 2019

Substrate Stiffness-Dependent Carbon Nanotube-Induced Lung Fibrogenesis.

Nano Lett 2019 08 5;19(8):5443-5451. Epub 2019 Aug 5.

Department of Biomedical Engineering , University of North Texas , Denton , Texas 76207 , United States.

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http://dx.doi.org/10.1021/acs.nanolett.9b01943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724206PMC
August 2019

Acquisition of Cancer Stem Cell-like Properties in Human Small Airway Epithelial Cells after a Long-term Exposure to Carbon Nanomaterials.

Environ Sci Nano 2019 Jul 24;6(7):2152-2170. Epub 2019 May 24.

Department of Pharmaceutical Sciences and WVU Cancer Institute, West Virginia University, Morgantown, West Virginia, 26506, United States.

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http://dx.doi.org/10.1039/C9EN00183BDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675031PMC
July 2019

Reactive oxygen species mediate cancer stem-like cells and determine bortezomib sensitivity via Mcl-1 and Zeb-1 in mantle cell lymphoma.

Biochim Biophys Acta Mol Basis Dis 2018 11 11;1864(11):3739-3753. Epub 2018 Sep 11.

Siriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Bangkok Hematology Center, Wattanosoth Hospital, BDMS Center of Excellence for Cancer, Bangkok, Thailand.

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http://dx.doi.org/10.1016/j.bbadis.2018.09.010DOI Listing
November 2018

Theaflavin-3, 3'-digallate inhibits ovarian cancer stem cells via suppressing Wnt/β-Catenin signaling pathway.

J Funct Foods 2018 Nov 25;50:1-7. Epub 2018 Sep 25.

College of Science, Technology and Mathematics, Alderson Broaddus University, Philippi, WV , USA.

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http://dx.doi.org/10.1016/j.jff.2018.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456259PMC
November 2018

Predicting Nanotube Fibrogenicity through Stem Cell-Mediated Fibroblast Focus and Spheroid Formation.

Nano Lett 2018 10 19;18(10):6500-6508. Epub 2018 Sep 19.

Department of Pharmaceutical Sciences , West Virginia University , Morgantown , West Virginia 26506 , United States.

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http://dx.doi.org/10.1021/acs.nanolett.8b03032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298034PMC
October 2018

Incineration of Nanoclay Composites Leads to Byproducts with Reduced Cellular Reactivity.

Sci Rep 2018 Jul 16;8(1):10709. Epub 2018 Jul 16.

Department of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV, 26506, USA.

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http://dx.doi.org/10.1038/s41598-018-28884-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048035PMC
July 2018

Synergistic effect of black tea polyphenol, theaflavin-3,3'-digallate with cisplatin against cisplatin resistant human ovarian cancer cells.

J Funct Foods 2018 Jul 26;46:1-11. Epub 2018 Apr 26.

College of Science, Technology and Mathematics, Alderson Broaddus University, Philippi, WV, USA.

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http://dx.doi.org/10.1016/j.jff.2018.04.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197486PMC
July 2018

Inhibition of -GlcNAcase Sensitizes Apoptosis and Reverses Bortezomib Resistance in Mantle Cell Lymphoma through Modification of Truncated Bid.

Mol Cancer Ther 2018 02 22;17(2):484-496. Epub 2017 Nov 22.

Siriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805589PMC
February 2018

Carbon nanotubes physicochemical properties influence the overall cellular behavior and fate.

NanoImpact 2018 Jan 28;9:72-84. Epub 2017 Oct 28.

Department of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1016/j.impact.2017.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753956PMC
January 2018

Theaflavin-3,3'-Digallate Enhances the Inhibitory Effect of Cisplatin by Regulating the Copper Transporter 1 and Glutathione in Human Ovarian Cancer Cells.

Int J Mol Sci 2018 Jan 2;19(1). Epub 2018 Jan 2.

College of Science, Technology and Mathematics, Alderson Broaddus University, Philippi, WV 26416, USA.

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http://dx.doi.org/10.3390/ijms19010117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796066PMC
January 2018

Detachment-induced E-cadherin expression promotes 3D tumor spheroid formation but inhibits tumor formation and metastasis of lung cancer cells.

Am J Physiol Cell Physiol 2017 Nov 20;313(5):C556-C566. Epub 2017 Sep 20.

Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand;

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http://dx.doi.org/10.1152/ajpcell.00096.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792170PMC
November 2017

Inhibitory effect of black tea pigments, theaflavin‑3/3'-gallate against cisplatin-resistant ovarian cancer cells by inducing apoptosis and G1 cell cycle arrest.

Int J Oncol 2017 Nov 3;51(5):1508-1520. Epub 2017 Oct 3.

College of Science, Technology and Mathematics, Alderson Broaddus University, Philippi, WV, USA.

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http://dx.doi.org/10.3892/ijo.2017.4145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642389PMC
November 2017

Anti-Tumor Effects of Cardiac Glycosides on Human Lung Cancer Cells and Lung Tumorspheres.

J Cell Physiol 2017 Sep 10;232(9):2497-2507. Epub 2017 Apr 10.

Department of Pharmaceutical Sciences, Hampton University School of Pharmacy, Hampton, Virginia.

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http://dx.doi.org/10.1002/jcp.25611DOI Listing
September 2017

Early Assessment and Correlations of Nanoclay's Toxicity to Their Physical and Chemical Properties.

ACS Appl Mater Interfaces 2017 Sep 5;9(37):32323-32335. Epub 2017 Sep 5.

Department of Chemical and Biomedical Engineering, West Virginia University , Morgantown, West Virginia 26506, United States.

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http://dx.doi.org/10.1021/acsami.7b06657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390283PMC
September 2017

SOX9 Regulates Cancer Stem-Like Properties and Metastatic Potential of Single-Walled Carbon Nanotube-Exposed Cells.

Sci Rep 2017 09 14;7(1):11653. Epub 2017 Sep 14.

West Virginia University Cancer Institute, West Virginia University, Morgantown, WV, 26506, United States.

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http://dx.doi.org/10.1038/s41598-017-12037-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599589PMC
September 2017

Induction of Slug by Chronic Exposure to Single-Walled Carbon Nanotubes Promotes Tumor Formation and Metastasis.

Chem Res Toxicol 2017 07 20;30(7):1396-1405. Epub 2017 Jun 20.

Health Effects Laboratory Division, National Institute for Occupational Safety and Health , Morgantown, West Virginia 26505, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.7b00049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774007PMC
July 2017

3-Hydroxyterphenyllin, a natural fungal metabolite, induces apoptosis and S phase arrest in human ovarian carcinoma cells.

Int J Oncol 2017 Apr 2;50(4):1392-1402. Epub 2017 Mar 2.

College of Science, Technology and Mathematics, Alderson Broaddus University, Philippi, WV 26416, USA.

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http://dx.doi.org/10.3892/ijo.2017.3894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363874PMC
April 2017

Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells.

Mol Cancer 2017 03 14;16(1):63. Epub 2017 Mar 14.

Department of Pharmaceutical Sciences, West Virginia University, 1 Medical Center Drive, Morgantown, WV, 26506, USA.

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http://dx.doi.org/10.1186/s12943-017-0633-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348784PMC
March 2017

Carbon Nanotubes Induced Fibrogenesis on Nanostructured Substrates.

Environ Sci Nano 2017 Mar 30;4(3):689-699. Epub 2017 Jan 30.

Department of Chemical and Biomedical Engineering, West Virginia University, Morgantown, West Virginia, USA, 26506.

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http://dx.doi.org/10.1039/C6EN00402DDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608452PMC
March 2017

Effects of titanium dioxide nanoparticles on human keratinocytes.

Drug Chem Toxicol 2017 Jan 16;40(1):90-100. Epub 2016 Jun 16.

a Department of Pharmaceutical Sciences , Hampton University , Hampton , VA , USA.

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http://dx.doi.org/10.1080/01480545.2016.1185111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161738PMC
January 2017

Toxicity evaluations of nanoclays and thermally degraded byproducts through spectroscopical and microscopical approaches.

Biochim Biophys Acta Gen Subj 2017 Jan 7;1861(1 Pt A):3406-3415. Epub 2016 Sep 7.

Department of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV 26506, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2016.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148634PMC
January 2017

Induction of cancer-associated fibroblast-like cells by carbon nanotubes dictates its tumorigenicity.

Sci Rep 2016 12 20;6:39558. Epub 2016 Dec 20.

Pharmaceutical and Pharmacological Sciences Program, West Virginia University, WV 26506, USA.

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http://dx.doi.org/10.1038/srep39558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172236PMC
December 2016

Role of mesothelin in carbon nanotube-induced carcinogenic transformation of human bronchial epithelial cells.

Am J Physiol Lung Cell Mol Physiol 2016 09 15;311(3):L538-49. Epub 2016 Jul 15.

Department of Pharmaceutical Sciences, West Virginia University, Morgantown, West Virginia; WVU Cancer Institute, West Virginia University, Morgantown, West Virginia; and

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http://dx.doi.org/10.1152/ajplung.00139.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142212PMC
September 2016

Carcinogenic Potential of High Aspect Ratio Carbon Nanomaterials.

Environ Sci Nano 2016 Jun 6;3(3):483-493. Epub 2016 Apr 6.

Department of Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506, USA; Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1039/C5EN00238ADOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996468PMC
June 2016

Direct stimulation of human fibroblasts by nCeO2 in vitro is attenuated with an amorphous silica coating.

Part Fibre Toxicol 2016 05 4;13(1):23. Epub 2016 May 4.

National Institute for Occupational Safety and Health, Health Effects Laboratory Division, 1095 Willowdale Road, Morgantown, WV, 26505, USA.

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http://dx.doi.org/10.1186/s12989-016-0134-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855843PMC
May 2016

Autophagy-Induced Apoptosis in Lung Cancer Cells by a Novel Digitoxin Analog.

J Cell Physiol 2016 04;231(4):817-28

Department of Pharmaceutical Sciences, School of Pharmacy, Hampton University, Hampton, Virginia.

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http://dx.doi.org/10.1002/jcp.25129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751068PMC
April 2016

Nanotopographical Modulation of Cell Function through Nuclear Deformation.

ACS Appl Mater Interfaces 2016 Mar 16;8(8):5082-92. Epub 2016 Feb 16.

Department of Chemical Engineering, West Virginia University , Morgantown, West Virginia 26506, United States.

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http://dx.doi.org/10.1021/acsami.5b10531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804753PMC
March 2016

Gallic acid, a phenolic compound, exerts anti-angiogenic effects via the PTEN/AKT/HIF-1α/VEGF signaling pathway in ovarian cancer cells.

Oncol Rep 2016 Jan 27;35(1):291-7. Epub 2015 Oct 27.

Key Laboratory for Quality Improvement of Agricultural Products of Zhejiang Province, College of Agriculture and Food Science, Zhejiang A & F University, Lin'an, Zhejiang 311300, P.R. China.

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http://dx.doi.org/10.3892/or.2015.4354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699619PMC
January 2016

Myricetin inhibits proliferation of cisplatin-resistant cancer cells through a p53-dependent apoptotic pathway.

Int J Oncol 2015 Oct 25;47(4):1494-502. Epub 2015 Aug 25.

College of Science, Technology and Mathematics, Alderson Broaddus University, Philippi, WV 26416, USA.

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http://dx.doi.org/10.3892/ijo.2015.3133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583523PMC
October 2015

Identification of TGF-β receptor-1 as a key regulator of carbon nanotube-induced fibrogenesis.

Am J Physiol Lung Cell Mol Physiol 2015 Oct 21;309(8):L821-33. Epub 2015 Aug 21.

Health Effects Laboratory Division (HELD), National Institute for Occupational Safety and Health, Morgantown, West Virginia; and Department of Pharmaceutical Sciences, West Virginia University, Morgantown, West Virginia

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http://dx.doi.org/10.1152/ajplung.00002.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609943PMC
October 2015

Response to Comment on "Appalachian Mountaintop Mining Particulate Matter Induces Neoplastic Transformation of Human Bronchial Epithelial Cells and Promotes Tumor Formation".

Environ Sci Technol 2015 Aug 24;49(15):9385. Epub 2015 Jul 24.

†Department of Pharmaceutical Sciences, West Virginia University, Morgantown, West Virginia 26506, United States;

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http://dx.doi.org/10.1021/acs.est.5b02314DOI Listing
August 2015

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:
William H Goodson Leroy Lowe David O Carpenter Michael Gilbertson Abdul Manaf Ali Adela Lopez de Cerain Salsamendi Ahmed Lasfar Amancio Carnero Amaya Azqueta Amedeo Amedei Amelia K Charles Andrew R Collins Andrew Ward Anna C Salzberg Annamaria Colacci Ann-Karin Olsen Arthur Berg Barry J Barclay Binhua P Zhou Carmen Blanco-Aparicio Carolyn J Baglole Chenfang Dong Chiara Mondello Chia-Wen Hsu Christian C Naus Clement Yedjou Colleen S Curran Dale W Laird Daniel C Koch Danielle J Carlin Dean W Felsher Debasish Roy Dustin G Brown Edward Ratovitski Elizabeth P Ryan Emanuela Corsini Emilio Rojas Eun-Yi Moon Ezio Laconi Fabio Marongiu Fahd Al-Mulla Ferdinando Chiaradonna Firouz Darroudi Francis L Martin Frederik J Van Schooten Gary S Goldberg Gerard Wagemaker Gladys N Nangami Gloria M Calaf Graeme Williams Gregory T Wolf Gudrun Koppen Gunnar Brunborg H Kim Lyerly Harini Krishnan Hasiah Ab Hamid Hemad Yasaei Hideko Sone Hiroshi Kondoh Hosni K Salem Hsue-Yin Hsu Hyun Ho Park Igor Koturbash Isabelle R Miousse A Ivana Scovassi James E Klaunig Jan Vondráček Jayadev Raju Jesse Roman John Pierce Wise Jonathan R Whitfield Jordan Woodrick Joseph A Christopher Josiah Ochieng Juan Fernando Martinez-Leal Judith Weisz Julia Kravchenko Jun Sun Kalan R Prudhomme Kannan Badri Narayanan Karine A Cohen-Solal Kim Moorwood Laetitia Gonzalez Laura Soucek Le Jian Leandro S D'Abronzo Liang-Tzung Lin Lin Li Linda Gulliver Lisa J McCawley Lorenzo Memeo Louis Vermeulen Luc Leyns Luoping Zhang Mahara Valverde Mahin Khatami Maria Fiammetta Romano Marion Chapellier Marc A Williams Mark Wade Masoud H Manjili Matilde E Lleonart Menghang Xia Michael J Gonzalez Michalis V Karamouzis Micheline Kirsch-Volders Monica Vaccari Nancy B Kuemmerle Neetu Singh Nichola Cruickshanks Nicole Kleinstreuer Nik van Larebeke Nuzhat Ahmed Olugbemiga Ogunkua P K Krishnakumar Pankaj Vadgama Paola A Marignani Paramita M Ghosh Patricia Ostrosky-Wegman Patricia A Thompson Paul Dent Petr Heneberg Philippa Darbre Po Sing Leung Pratima Nangia-Makker Qiang Shawn Cheng R Brooks Robey Rabeah Al-Temaimi Rabindra Roy Rafaela Andrade-Vieira Ranjeet K Sinha Rekha Mehta Renza Vento Riccardo Di Fiore Richard Ponce-Cusi Rita Dornetshuber-Fleiss Rita Nahta Robert C Castellino Roberta Palorini Roslida Abd Hamid Sabine A S Langie Sakina E Eltom Samira A Brooks Sandra Ryeom Sandra S Wise Sarah N Bay Shelley A Harris Silvana Papagerakis Simona Romano Sofia Pavanello Staffan Eriksson Stefano Forte Stephanie C Casey Sudjit Luanpitpong Tae-Jin Lee Takemi Otsuki Tao Chen Thierry Massfelder Thomas Sanderson Tiziana Guarnieri Tove Hultman Valérian Dormoy Valerie Odero-Marah Venkata Sabbisetti Veronique Maguer-Satta W Kimryn Rathmell Wilhelm Engström William K Decker William H Bisson Yon Rojanasakul Yunus Luqmani Zhenbang Chen Zhiwei Hu

Carcinogenesis 2015 Jun;36 Suppl 1:S254-96

Department of Surgery, The Ohio State University College of Medicine, The James Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
Web Search
http://www.ilcambiamento.it/files/carcinogenesi.pdf
Web Search
http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
Publisher Site
http://dx.doi.org/10.1093/carcin/bgv039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480130PMC
June 2015

Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death.

Carcinogenesis 2015 Jun;36 Suppl 1:S89-110

Department of Chemistry and Biochemistry, Yeungnam University, Gyeongsan 712-749, South Korea, Sultan Zainal Abidin University, Malaysia, Plant Biotechnologies Inc, St. Albert AB, Canada, Computer Science Department, Southern Illinois University, Carbondale, IL 62901, USA, Department of Urology, University of California Davis, Sacramento, CA 95817, USA, Department of Pharmacology and Toxicology, University of Vienna, Austria, University of Puerto Rico, Medical Sciences Campus, School of Public Health, Nutrition Program, San Juan Puerto Rico 00936-5067, USA, Department of Anatomy, College of Medicine, Yeungnam University, Daegu, 705-717, South Korea, School of Biomedical Science, The Chinese University Of Hong Kong, Hong Kong, China, Siriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand, Department of Otolaryngology/Head and Neck Surgery, Head and Neck Cancer Research Division, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, Department of Pharmaceutical Sciences, Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA, Department of Molecular Medicine and Medical Biotechnology, Federico II University of Naples, 80131 Naples, Italy, Department of Molecular and Experimental Medicine, MEM 180, The Scripps Research Institute, La Jolla, CA 92037, USA, Department of Biology, Jackson State University, Jackson, MS 39217, USA, Department of Pathology, Kuwait University, Safat 13110, Kuwait, Department of Experimental and Clinical Medicine, University of Firenze, Firenze, 50134, Italy, Department of Environmental and Radiological Health Sciences, Colorado state University/ Colorado School of Public Health, Fort Collins, CO 80523-1680, USA, Center for Environmental Carcinogenesis and Risk Assessment, Environmental Protection and Health Prevention Agency, Bologna, 40126, Italy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Se

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http://dx.doi.org/10.1093/carcin/bgv032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565614PMC
June 2015

Microfluidic gradient device for studying mesothelial cell migration and the effect of chronic carbon nanotube exposure.

J Micromech Microeng 2015 Jun;25(7)

Lane Department of Computer Science and Electrical Engineering, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1088/0960-1317/25/7/075010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770811PMC
June 2015

Dietary compounds galangin and myricetin suppress ovarian cancer cell angiogenesis.

J Funct Foods 2015 May;15:464-475

College of Science, Technology & Mathematics, Alderson Broaddus University, Philippi, WV 26416, USA.

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http://dx.doi.org/10.1016/j.jff.2015.03.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476554PMC
May 2015

Gene expression profile of human lung epithelial cells chronically exposed to single-walled carbon nanotubes.

Nanoscale Res Lett 2015 27;10:12. Epub 2015 Jan 27.

Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26505 USA.

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http://dx.doi.org/10.1186/s11671-014-0707-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314466PMC
April 2015

Selecting bioactive phenolic compounds as potential agents to inhibit proliferation and VEGF expression in human ovarian cancer cells.

Oncol Lett 2015 Mar 22;9(3):1444-1450. Epub 2014 Dec 22.

Key Laboratory for Quality Improvement of Agricultural Products of Zhejiang Province, College of Agriculure and Food Science, Zhejiang A & F University, Lin'an, Zhejiang 311300, P.R. China ; College of Science, Technology and Mathematics, Alderson Broaddus University, Philippi, WV 26416, USA.

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http://dx.doi.org/10.3892/ol.2014.2818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314987PMC
March 2015

Carbon nanotubes induce apoptosis resistance of human lung epithelial cells through FLICE-inhibitory protein.

Toxicol Sci 2015 Feb 19;143(2):499-511. Epub 2014 Nov 19.

*Department of Pharmaceutical Sciences, West Virginia University, Morgantown, West Virginia 26506, Department of Pharmacology and Physiology, Chulalongkorn University, Bangkok, Thailand, Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, West Virginia 26506, Siriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, Allergy and Clinical Immunology Branch, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, and National Nanotechnology Center, Pathumthani, Thailand *Department of Pharmaceutical Sciences, West Virginia University, Morgantown, West Virginia 26506, Department of Pharmacology and Physiology, Chulalongkorn University, Bangkok, Thailand, Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, West Virginia 26506, Siriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, Allergy and Clinical Immunology Branch, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, and National Nanotechnology Center, Pathumthani, Thailand

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https://academic.oup.com/toxsci/article/1677819/Carbon
Publisher Site
http://dx.doi.org/10.1093/toxsci/kfu251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306727PMC
February 2015

S-nitrosylation of FLICE inhibitory protein determines its interaction with RIP1 and activation of NF-κB.

Cell Cycle 2014 24;13(12):1948-57. Epub 2014 Apr 24.

Department of Pharmaceutical Sciences; West Virginia University; Morgantown, WV USA; Mary Babb Randolph Cancer Center; West Virginia University; Morgantown, WV USA.

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http://dx.doi.org/10.4161/cc.28898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111758PMC
January 2015

Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cells.

Cancer Lett 2015 Jan 7;356(2 Pt B):418-33. Epub 2014 Oct 7.

College of Science, Technology and Mathematics, Alderson Broaddus University, Philippi, WV 26416, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.09.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351971PMC
January 2015

Nitric oxide induces cancer stem cell-like phenotypes in human lung cancer cells.

Am J Physiol Cell Physiol 2015 Jan 19;308(2):C89-100. Epub 2014 Nov 19.

Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand; Cell-Based Drug and Health Products Development Research Unit, Chulalongkorn University, Bangkok, Thailand;

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http://dx.doi.org/10.1152/ajpcell.00187.2014DOI Listing
January 2015

Protein nanoparticles as drug delivery carriers for cancer therapy.

Biomed Res Int 2014 20;2014:180549. Epub 2014 Mar 20.

Department of Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506, USA ; Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1155/2014/180549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977416PMC
December 2014

Luciferase reporter cells as a platform to detect SMAD-dependent collagen production.

J Biosci Bioeng 2014 Dec 25;118(6):732-5. Epub 2014 Jun 25.

Department of Pharmaceutical Sciences, West Virginia University, 1 Medical Center Drive, Morgantown, WV 26506, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jbiosc.2014.05.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253305PMC
December 2014

Towards Elucidating the Effects of Purified MWCNTs on Human Lung Epithelial cells.

Environ Sci Nano 2014 Dec;1(6):95-603

Department of Chemical Engineering, West Virginia University, Morgantown WV, 26506, USA.

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http://dx.doi.org/10.1039/C4EN00102HDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254708PMC
December 2014

Nitrosothiol signaling and protein nitrosation in cell death.

Nitric Oxide 2014 Nov 23;42:9-18. Epub 2014 Jul 23.

Department of Pharmaceutical Sciences, Hampton University, Hampton, VA 23668, USA.

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http://dx.doi.org/10.1016/j.niox.2014.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258442PMC
November 2014

Caveolin-1 regulates lung cancer stem-like cell induction and p53 inactivation in carbon nanotube-driven tumorigenesis.

Oncotarget 2014 Jun;5(11):3541-54

Pharmaceutical and Pharmacological Sciences Program; Mary Babb Randolph Cancer Center, West Virginia University, WV 26506, USA.

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http://dx.doi.org/10.18632/oncotarget.1956DOI Listing
June 2014

Role of H-Ras/ERK signaling in carbon nanotube-induced neoplastic-like transformation of human mesothelial cells.

Front Physiol 2014 12;5:222. Epub 2014 Jun 12.

Department of Pharmaceutical Sciences, West Virginia University Morgantown, WV, USA ; Department of Medicine, Mary Babb Randolph Cancer Center, West Virginia University Morgantown, WV, USA.

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http://journal.frontiersin.org/article/10.3389/fphys.2014.00
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http://dx.doi.org/10.3389/fphys.2014.00222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054652PMC
June 2014

Induction of stem-like cells with malignant properties by chronic exposure of human lung epithelial cells to single-walled carbon nanotubes.

Part Fibre Toxicol 2014 May 11;11:22. Epub 2014 May 11.

Pharmaceutical and Pharmacological Sciences Program, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1186/1743-8977-11-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040122PMC
May 2014

The effects of carbon nanotubes on lung and dermal cellular behaviors.

Nanomedicine (Lond) 2014 May;9(6):895-912

Pharmaceutical & Pharmacological Sciences Program, West Virginia University, WV 26506, USA.

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http://dx.doi.org/10.2217/nnm.14.42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710349PMC
May 2014

Mechanisms of nanoparticle-induced oxidative stress and toxicity.

Biomed Res Int 2013 20;2013:942916. Epub 2013 Aug 20.

Department of Pharmaceutical Sciences and Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1155/2013/942916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762079PMC
April 2014

Effect of fiber length on carbon nanotube-induced fibrogenesis.

Int J Mol Sci 2014 Apr 29;15(5):7444-61. Epub 2014 Apr 29.

Department of Pharmaceutical Sciences, West Virginia University, 1, Medical Center Drive, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.3390/ijms15057444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057682PMC
April 2014

Potential Occupational Risks Associated with Pulmonary Toxicity of Carbon Nanotubes.

Occup Med Health Aff 2014;2

Department of Pharmaceutical Sciences, West Virginia University, Morgantown, USA ; Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.4172/2329-6879.1000165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300531PMC
January 2014

The aryl hydrocarbon receptor interacts with nuclear factor erythroid 2-related factor 2 to mediate induction of NAD(P)H:quinoneoxidoreductase 1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Arch Biochem Biophys 2013 Sep 22;537(1):31-8. Epub 2013 Jun 22.

Department of Occupational and Environmental Health, School of Public Health, Wuhan University, China.

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http://dx.doi.org/10.1016/j.abb.2013.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597779PMC
September 2013

Chronic exposure to carbon nanotubes induces invasion of human mesothelial cells through matrix metalloproteinase-2.

ACS Nano 2013 Sep 12;7(9):7711-23. Epub 2013 Aug 12.

Department of Pharmaceutical Sciences and Mary Babb Randolph Cancer Center, ‡Department of Chemical Engineering, and §Department of Computer Science and Electrical Engineering, West Virginia University , Morgantown, West Virginia 26506, United States.

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http://pubs.acs.org/doi/10.1021/nn402241b
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875633PMC
September 2013

Exposure to carbon nanotubes leads to changes in the cellular biomechanics.

Adv Healthc Mater 2013 Jul 18;2(7):945-51. Epub 2013 Jan 18.

Department of Chemical Engineering, West Virginia University, Morgantown WV 26506, USA.

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http://dx.doi.org/10.1002/adhm.201200430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602160PMC
July 2013

Reactive oxygen species-mediated p38 MAPK regulates carbon nanotube-induced fibrogenic and angiogenic responses.

Nanotoxicology 2013 Mar 20;7(2):157-68. Epub 2012 Jan 20.

Department of Pharmaceutical Sciences, Hampton University, Hampton, VA 23668, USA.

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http://dx.doi.org/10.3109/17435390.2011.647929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089498PMC
March 2013

Pulmonary toxicity and fibrogenic response of carbon nanotubes.

Toxicol Mech Methods 2013 Mar 16;23(3):196-206. Epub 2013 Jan 16.

Department of Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.3109/15376516.2012.753967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593477PMC
March 2013

Regulation of apoptosis by Bcl-2 cysteine oxidation in human lung epithelial cells.

Mol Biol Cell 2013 Mar 30;24(6):858-69. Epub 2013 Jan 30.

Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1091/mbc.E12-10-0747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596255PMC
March 2013

Linking JNK-STAT3-Akt signaling axis to EZH2 phosphorylation: a novel pathway of carcinogenesis.

Authors:
Yon Rojanasakul

Cell Cycle 2013 Jan 15;12(2):202-3. Epub 2012 Jan 15.

Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV, USA.

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http://dx.doi.org/10.4161/cc.23419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575446PMC
January 2013

Glutathione conjugation of busulfan produces a hydroxyl radical-trapping dehydroalanine metabolite.

Xenobiotica 2012 Dec 22;42(12):1170-7. Epub 2012 Jun 22.

Department of Basic Pharmaceutical Sciences and Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.3109/00498254.2012.696740DOI Listing
December 2012

Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells.

Am J Physiol Cell Physiol 2012 May 25;302(9):C1284-92. Epub 2012 Jan 25.

Pharmaceutical Technology (International) Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.

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http://dx.doi.org/10.1152/ajpcell.00318.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774262PMC
May 2012

Digitoxin and its analogs as novel cancer therapeutics.

Exp Hematol Oncol 2012 Apr 5;1(1). Epub 2012 Apr 5.

Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV, USA.

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http://dx.doi.org/10.1186/2162-3619-1-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506989PMC
April 2012

AC927, a σ receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cells.

Mol Pharmacol 2012 Mar 18;81(3):299-308. Epub 2011 Nov 18.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University Health Sciences Center, Morgantown, West Virginia 26506, USA.

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http://dx.doi.org/10.1124/mol.111.074120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286303PMC
March 2012

An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages.

Immunity 2012 Mar 21;36(3):464-76. Epub 2012 Feb 21.

Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.immuni.2012.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315380PMC
March 2012

Digitoxin and a synthetic monosaccharide analog inhibit cell viability in lung cancer cells.

Toxicol Appl Pharmacol 2012 Jan 18;258(1):51-60. Epub 2011 Oct 18.

Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1016/j.taap.2011.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254807PMC
January 2012

Nitrosothiol Signaling in Anoikis Resistance and Cancer Metastasis.

For Immunopathol Dis Therap 2012 Jan;3(2):141-154

Department of Pharmaceutical Sciences, Hampton University, Hampton, Virginia.

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http://dx.doi.org/10.1615/ForumImmunDisTher.2012006115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593302PMC
January 2012

Arsenite induces cell transformation by reactive oxygen species, AKT, ERK1/2, and p70S6K1.

Biochem Biophys Res Commun 2011 Oct 24;414(3):533-8. Epub 2011 Sep 24.

Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, United States.

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http://dx.doi.org/10.1016/j.bbrc.2011.09.102DOI Listing
October 2011

Antioxidant c-FLIP inhibits Fas ligand-induced NF-kappaB activation in a phosphatidylinositol 3-kinase/Akt-dependent manner.

J Immunol 2011 Sep 19;187(6):3256-66. Epub 2011 Aug 19.

Department of Pharmaceutical Sciences, Hampton University, Hampton, VA 23668, USA.

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http://dx.doi.org/10.4049/jimmunol.1002915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169770PMC
September 2011

Nanomaterials in humans: identification, characteristics, and potential damage.

Toxicol Pathol 2011 Aug 18;39(5):841-9. Epub 2011 Jul 18.

Department of Occupational Medicine and Clinical Toxicology, Beijing Chaoyang Hospital, Capital University of Medical Sciences, Beijing, China.

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http://dx.doi.org/10.1177/0192623311413787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706159PMC
August 2011

Carbon nanotubes induce malignant transformation and tumorigenesis of human lung epithelial cells.

Nano Lett 2011 Jul 9;11(7):2796-803. Epub 2011 Jun 9.

Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States.

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http://dx.doi.org/10.1021/nl2011214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135732PMC
July 2011

C5'-Alkyl Substitution Effects on Digitoxigenin α-l-Glycoside Cancer Cytotoxicity.

ACS Med Chem Lett 2011 Apr;2(4):259-263

Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/ml100291nDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092485PMC
April 2011

Synthesis and Evaluation of the α-D-/α-L-Rhamnosyl and Amicetosyl Digitoxigenin Oligomers as Anti-tumor Agents.

ACS Med Chem Lett 2011 Apr;2(4):264-269

Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/ml100290dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108330PMC
April 2011

Hydrogen peroxide inhibits non-small cell lung cancer cell anoikis through the inhibition of caveolin-1 degradation.

Am J Physiol Cell Physiol 2011 Feb 9;300(2):C235-45. Epub 2010 Dec 9.

Dept. of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand 10330.

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http://www.physiology.org/doi/10.1152/ajpcell.00249.2010
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http://dx.doi.org/10.1152/ajpcell.00249.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043638PMC
February 2011