Yok-Ai Que

Yok-Ai Que

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Yok-Ai Que

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Associations between clinical characteristics and the development of multiple organ failure after severe burns in adult patients.

Burns 2019 Dec 2;45(8):1775-1782. Epub 2019 Nov 2.

Department of Surgery, Massachusetts General Hospital and Harvard Medical School, 340 Thier Research Building, 50 Blossom Street, Boston MA 02114, USA; Shriners Hospitals for Children, 51 Blossom St., Boston, MA 02114, USA; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Ave. Louis Pasteur, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.burns.2019.02.014DOI Listing
December 2019

Bacteriophages Improve Outcomes in Experimental Ventilator-associated Pneumonia.

Am J Respir Crit Care Med 2019 Nov;200(9):1126-1133

Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1164/rccm.201812-2372OCDOI Listing
November 2019

Draft Genome Sequence of Methicillin-Resistant Staphylococcus aureus Strain AW7, Isolated from a Patient with Bacteremia.

Microbiol Resour Announc 2019 Oct 3;8(40). Epub 2019 Oct 3.

Department of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1128/MRA.00806-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776766PMC
October 2019

Efficacy of newly isolated and highly potent bacteriophages in a mouse model of extensively drug-resistant Acinetobacter baumannii bacteraemia.

J Glob Antimicrob Resist 2019 May 14;19:255-261. Epub 2019 May 14.

Department of Fundamental Microbiology, University of Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jgar.2019.05.005DOI Listing
May 2019

Transcriptome Analysis of Cultured in Human Burn Wound Exudates.

Front Cell Infect Microbiol 2018 27;8:39. Epub 2018 Feb 27.

Microbiology Unit, Department of Botany and Plant Biology, Sciences III, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.3389/fcimb.2018.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835353PMC
February 2019

Measurement of pancreatic stone protein in the identification and management of sepsis.

Biomark Med 2019 02 23;13(2):135-145. Epub 2019 Jan 23.

Abionic SA, Route de la Corniche 5, 1066 Epalinges, Switzerland.

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http://dx.doi.org/10.2217/bmm-2018-0194DOI Listing
February 2019

Computational prediction of inter-species relationships through omics data analysis and machine learning.

BMC Bioinformatics 2018 Nov 20;19(Suppl 14):420. Epub 2018 Nov 20.

School of Business and Engineering Vaud (HEIG-VD), University of Applied Sciences Western Switzerland (HES-SO), Route. de Cheseaux 1, Yverdon-Les-Bains, 1400, Switzerland.

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http://dx.doi.org/10.1186/s12859-018-2388-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245486PMC
November 2018

Population Pharmacokinetic Study of Amoxicillin-Treated Burn Patients Hospitalized at a Swiss Tertiary-Care Center.

Antimicrob Agents Chemother 2018 09 27;62(9). Epub 2018 Aug 27.

Division of Clinical Pharmacology, Service of Biomedecine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

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http://dx.doi.org/10.1128/AAC.00505-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125536PMC
September 2018

Phage Therapy: A New Horizon in the Antibacterial Treatment of Oral Pathogens.

Curr Top Med Chem 2017 ;17(10):1199-1211

Department of Prosthodontics, Hebrew University-Hadassah School of Dental Medicine, Jerusalem, Israel.

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http://www.eurekaselect.com/openurl/content.php?genre=articl
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http://dx.doi.org/10.2174/1568026616666160930145649DOI Listing
April 2017

TNF-α/IL-10 Ratio Correlates with Burn Severity and May Serve as a Risk Predictor of Increased Susceptibility to Infections.

Front Public Health 2016 5;4:216. Epub 2016 Oct 5.

Department of Surgery, Massachusetts General Hospital, Boston, MA, USA; Department of Microbiology and Immunology, Harvard Medical School, Boston, MA, USA; Shriners Hospitals for Children-Boston®, Boston, MA, USA.

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http://dx.doi.org/10.3389/fpubh.2016.00216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050217PMC
October 2016

Effect of Human Burn Wound Exudate on Pseudomonas aeruginosa Virulence.

mSphere 2016 Mar-Apr;1(2). Epub 2016 Apr 27.

Microbiology Unit, Department of Botany and Plant Biology, Sciences III, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1128/mSphere.00111-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894682PMC
June 2016

Auto Poisoning of the Respiratory Chain by a Quorum-Sensing-Regulated Molecule Favors Biofilm Formation and Antibiotic Tolerance.

Curr Biol 2016 Jan 14;26(2):195-206. Epub 2016 Jan 14.

Department of Surgery and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA; Department of Surgery, Center for Surgery, Innovation and Bioengineering, Massachusetts General Hospital, Boston, MA 02114, USA; Shriners Hospitals for Children Boston, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.11.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729643PMC
January 2016

Effective treatment of invasive Aspergillus fumigatus infection using combinations of topical and systemic antifungals in a severely burned patient.

J Burn Care Res 2015 Mar-Apr;36(2):e85-9

From the *Service of Pharmacy, ‡Service of Intensive Care Medicine, §Service of Plastic and Reconstructive Surgery, ‖Institute of Microbiology, ¶Service of Infectious Diseases, and #Service of Pathology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Switzerland; **Centre des Brûlés, Centre Hospitalier St. Joseph et St Luc, Lyon, France; and †School of Pharmaceutical Sciences, University of Geneva, University of Lausanne.

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http://dx.doi.org/10.1097/BCR.0000000000000143DOI Listing
November 2015

Prognostication of Mortality in Critically Ill Patients With Severe Infections.

Chest 2015 Sep;148(3):674-682

Department of Adult Intensive Care Medicine, University Hospital Medical Center and University of Lausanne, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1378/chest.15-0123DOI Listing
September 2015

Impact of the introduction of real-time therapeutic drug monitoring on empirical doses of carbapenems in critically ill burn patients.

Burns 2015 Aug 10;41(5):956-68. Epub 2015 Feb 10.

Service of Intensive Care Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.burns.2015.01.001DOI Listing
August 2015

Reply to Eisen and McBryde.

J Infect Dis 2015 Aug 9;212(4):674-5. Epub 2015 Mar 9.

Department of Fundamental Microbiology, University of Lausanne.

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http://dx.doi.org/10.1093/infdis/jiv133DOI Listing
August 2015

Do standard burn mortality formulae work on a population of severely burned children and adults?

Burns 2015 Aug 25;41(5):935-45. Epub 2015 Apr 25.

Department of Surgery, Massachusetts General Hospital, Bigelow 1302, 55 Fruit Street, Boston, MA 02114, USA; Shriners Hospitals for Children-Boston®, 51 Blossom St., Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.burns.2015.03.017DOI Listing
August 2015

Vaccination against Staphylococcus aureus experimental endocarditis using recombinant Lactococcus lactis expressing ClfA or FnbpA.

Vaccine 2015 Jul 3;33(30):3512-7. Epub 2015 Jun 3.

Department of Fundamental Microbiology, University of Lausanne, CH-1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.05.060DOI Listing
July 2015

Prediction of multiple infections after severe burn trauma: a prospective cohort study.

Ann Surg 2015 Apr;261(4):781-92

*Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA †Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA ‡Shriners Hospitals for Children Boston, Boston, MA §Department of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland ¶Department of Biochemistry and Stanford Genome Technology Center, Stanford University School of Medicine, Palo Alto, CA ‖Department of Biomedical Engineering, Worcester Polytechnic Institute, Worchester, MA **Program in Bioinformatics and Computational Biology, Worcester Polytechnic Institute, Worchester, MA.

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http://dx.doi.org/10.1097/SLA.0000000000000759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284150PMC
April 2015

Preventing invasive candida infections. Where could we do better?

J Hosp Infect 2015 Apr 16;89(4):302-8. Epub 2014 Dec 16.

Adult Critical Care Medicine and Burn Unit, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.jhin.2014.11.006DOI Listing
April 2015

Targeting Enterococcus faecalis biofilms with phage therapy.

Appl Environ Microbiol 2015 Apr 6;81(8):2696-705. Epub 2015 Feb 6.

Faculty of Dental Sciences, Hebrew University-Hadassah School of Dental Medicine, Jerusalem, Israel The Israeli Institute for Advanced Research, Rehovot, Israel

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http://aem.asm.org/content/early/2015/02/02/AEM.00096-15.ful
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http://aem.asm.org/content/81/8/2696.full.pdf
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http://dx.doi.org/10.1128/AEM.00096-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375334PMC
April 2015

Low C-reactive protein values at admission predict mortality in patients with severe community-acquired pneumonia caused by Streptococcus pneumoniae that require intensive care management.

Infection 2015 Apr 3;43(2):193-9. Epub 2015 Mar 3.

Department of Intensive Care Medicine, Centre Hospitalier Universitaire Vaudois (CHUV), University of Lausanne, Rue du Bugnon 46, 1011, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s15010-015-0755-0DOI Listing
April 2015

Assessing Pseudomonas aeruginosa Persister/antibiotic tolerant cells.

Methods Mol Biol 2014 ;1149:699-707

Department of Surgery, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-1-4939-0473-0_54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538066PMC
March 2015

Sputum containing zinc enhances carbapenem resistance, biofilm formation and virulence of Pseudomonas aeruginosa.

Microb Pathog 2014 Dec 22;77:36-41. Epub 2014 Oct 22.

Microbiology Unit, Department of Botany and Plant Biology, Sciences III, University of Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.micpath.2014.10.011DOI Listing
December 2014

A quorum sensing small volatile molecule promotes antibiotic tolerance in bacteria.

PLoS One 2013 19;8(12):e80140. Epub 2013 Dec 19.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America ; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America ; Shriners Hospitals for Children Boston, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080140PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868577PMC
October 2014

Carnitine deficiency in chronic critical illness.

Curr Opin Clin Nutr Metab Care 2014 Mar;17(2):200-9

aCenter for Molecular Diseases, Lausanne University Hospital bAdult Intensive Care & Burns, Lausanne University Hospital, Lausanne, Switzerland cDivision of Endocrinology, Diabetes, and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1097/MCO.0000000000000037DOI Listing
March 2014

[Continuous renal replacement therapy for acute kidney injury].

Rev Med Suisse 2013 Dec;9(410):2324, 2326-9

Service de médecine intensive adulte, CHUV 1011, Lausanne.

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December 2013

The quorum sensing volatile molecule 2-amino acetophenon modulates host immune responses in a manner that promotes life with unwanted guests.

PLoS Pathog 2012 15;8(11):e1003024. Epub 2012 Nov 15.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1003024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499575PMC
April 2013

Production of Pseudomonas aeruginosa Intercellular Small Signaling Molecules in Human Burn Wounds.

J Pathog 2011 17;2011:549302. Epub 2011 Mar 17.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA ; Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.4061/2011/549302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594954PMC
March 2013

A method for high throughput determination of viable bacteria cell counts in 96-well plates.

BMC Microbiol 2012 Nov 13;12:259. Epub 2012 Nov 13.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1186/1471-2180-12-259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534621PMC
November 2012

Infective endocarditis.

Nat Rev Cardiol 2011 Jun 12;8(6):322-36. Epub 2011 Apr 12.

Department of Intensive Care Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Rue du Bugnon 46, Lausanne, Switzerland.

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http://www.nature.com/articles/nrcardio.2011.43
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http://dx.doi.org/10.1038/nrcardio.2011.43DOI Listing
June 2011

Bioinformatics assistance of metabolic and nutrition management in the ICU.

Curr Opin Clin Nutr Metab Care 2011 Mar;14(2):202-8

Service de Médecine Intensive Adulte et Centre des Brûlés, University Hospital, Rue du Bugnon 46, Lausanne, Switzerland.

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http://dx.doi.org/10.1097/MCO.0b013e328341ed77DOI Listing
March 2011

Contribution of (sub)domains of Staphylococcus aureus fibronectin-binding protein to the proinflammatory and procoagulant response of human vascular endothelial cells.

Thromb Haemost 2009 Mar;101(3):495-504

Leiden University Medical Center, Department of Infectious Diseases, room C5-38, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.

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March 2009

Fibronectin-binding proteins and clumping factor A in Staphylococcus aureus experimental endocarditis: FnBPA is sufficient to activate human endothelial cells.

Thromb Haemost 2007 Apr;97(4):617-26

Department of Paediatric Cardiology, University Children's Hospital, Duesseldorf, Germany.

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April 2007

Images in cardiovascular medicine. Rapid resolution of massive lung abscesses complicating tricuspid-valve endocarditis.

Circulation 2006 Oct;114(14):e523-4

Department of Intensive Care Medicine, University Hospital, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.626317DOI Listing
October 2006

New concepts in the pathophysiology of infective endocarditis.

Curr Infect Dis Rep 2006 Jun;8(4):271-9

Department of Fundamental Microbiology, University of Lausanne, Biophore building, CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s11908-006-0071-zDOI Listing
June 2006

[Infective endocarditis: update].

Rev Med Suisse Romande 2004 Jun;124(6):341-6

Division des soins intensifs de médecine, Département de Médecine interne, CHUV Lausanne.

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June 2004

Infective endocarditis.

Lancet 2004 Jan;363(9403):139-49

Institute of Fundamental Microbiology, Centre Hospitalier Universitaire, University of Lausanne, Switzerland.

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http://dx.doi.org/10.1016/S0140-6736(03)15266-XDOI Listing
January 2004