Publications by authors named "Yoichiro Iwakura"

503 Publications

TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens.

Nat Commun 2021 01 4;12(1):94. Epub 2021 Jan 4.

Center for Animal Disease Models, Research Institute for Biomedical Sciences (RIBS), Tokyo University of Science, Noda, Chiba, 278-0022, Japan.

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January 2021

Psoriasis-like skin disorder in transgenic mice expressing a RIG-I Singleton-Merten syndrome variant.

Int Immunol 2020 Oct 29. Epub 2020 Oct 29.

Laboratory of Regulatory Information, Institute for Frontier Life and Medical Science, Kyoto University, Japan.

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October 2020

Distinct Roles for Dectin-1 and Dectin-2 in Skin Wound Healing and Neutrophilic Inflammatory Responses.

J Invest Dermatol 2021 Jan 5;141(1):164-176.e8. Epub 2020 Jun 5.

Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan; Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

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January 2021

Innate Immune Functions of Astrocytes are Dependent Upon Tumor Necrosis Factor-Alpha.

Sci Rep 2020 04 27;10(1):7047. Epub 2020 Apr 27.

Department of Medicine, Geisel School of Medicine at Dartmouth, Dartmouth College, One Medical Center Drive, Lebanon, NH, 03756, USA.

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April 2020

IL-17A promotes fatty acid uptake through the IL-17A/IL-17RA/p-STAT3/FABP4 axis to fuel ovarian cancer growth in an adipocyte-rich microenvironment.

Cancer Immunol Immunother 2020 Jan 4;69(1):115-126. Epub 2019 Dec 4.

Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Medical University, No. 22 Qixiangtai Road, Heping District, Tianjin, 300070, China.

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January 2020

IFN-γ and IL-17A regulate intestinal crypt production of CXCL10 in the healthy and inflamed colon.

Am J Physiol Gastrointest Liver Physiol 2020 03 2;318(3):G479-G489. Epub 2019 Dec 2.

Department of Immunology and Microbial Disease, Albany Medical College, Albany, New York.

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March 2020

Cutaneous p38 mitogen-activated protein kinase activation triggers psoriatic dermatitis.

J Allergy Clin Immunol 2019 10 1;144(4):1036-1049. Epub 2019 Aug 1.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Skin Research Institute of Singapore (SRIS), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore. Electronic address:

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October 2019

Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis.

J Clin Invest 2019 06 6;129(9):3610-3624. Epub 2019 Jun 6.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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June 2019

Large Scale Calcium Imaging of the Cerebellar Vermis During Sensory Stimulus Unravels Two Response's Components That Differ in Their Spatiotemporal Properties.

Front Syst Neurosci 2019 8;13:18. Epub 2019 May 8.

Department of Neurobiology, Silberman Institute of Life Sciences and Edmond & Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem, Israel.

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May 2019

CARD9 microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment.

Nat Immunol 2019 05 17;20(5):559-570. Epub 2019 Apr 17.

Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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May 2019

Uncoupling the Senescence-Associated Secretory Phenotype from Cell Cycle Exit via Interleukin-1 Inactivation Unveils Its Protumorigenic Role.

Mol Cell Biol 2019 06 28;39(12). Epub 2019 May 28.

Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, USA

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June 2019

Myeloid C-type lectin receptors in skin/mucoepithelial diseases and tumors.

J Leukoc Biol 2019 10 9;106(4):903-917. Epub 2019 Apr 9.

Center for Animal Disease Models, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Japan.

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October 2019

IL-1β Plays an Important Role in Pressure Overload-Induced Atrial Fibrillation in Mice.

Biol Pharm Bull 2019 ;42(4):543-546

Division of Molecular and Cellular Pharmacology, Department of Pathophysiology and Pharmacology, School of Pharmaceutical Sciences, Iwate Medical University.

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August 2019

Epidermal loss of phospholipase Cδ1 attenuates irritant contact dermatitis.

Biochem Biophys Res Commun 2019 04 18;511(2):330-335. Epub 2019 Feb 18.

Laboratory of Genome and Biosignals, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan; AMED-CREST, Japan Agency for Medical Research and Development, Tokyo, Japan. Electronic address:

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April 2019

Dectin-1 Contributes to Myocardial Ischemia/Reperfusion Injury by Regulating Macrophage Polarization and Neutrophil Infiltration.

Circulation 2019 01;139(5):663-678

Departments of Cardiology (Q.F., R.T., H.Z., H.X., L.L., J.H., Q.Z., W.S., R.Z., X.Y.), Shanghai Jiaotong University School of Medicine, PR China.

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January 2019

IL-36α is involved in hapten-specific T-cell induction, but not local inflammation, during contact hypersensitivity.

Biochem Biophys Res Commun 2018 11 22;506(3):429-436. Epub 2018 Oct 22.

Laboratory of Systems Biology, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan. Electronic address:

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November 2018

A dendritic cell-based systemic vaccine induces long-lived lung-resident memory Th17 cells and ameliorates pulmonary mycosis.

Mucosal Immunol 2019 01 2;12(1):265-276. Epub 2018 Oct 2.

Department of Chemotherapy and Mycoses, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan.

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January 2019

The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception.

iScience 2018 Aug 15;6:306-318. Epub 2018 Aug 15.

Thermal Biology group, Exploratory Research Center on Life and Living Systems National Institutes of Natural Sciences, Okazaki Aichi 444-8787, Japan; Division of Cell Signaling, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki, Aichi 444-8787, Japan; Department of Physiological Sciences, the Graduate University for Advanced Studies, Aichi 444-8787, Japan; Institute for Environmental and Gender Specific Medicine, Juntendo University, 2-1-1 Tomioka, Urayasu, Chiba 279-0021, Japan. Electronic address:

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August 2018