Publications by authors named "Yoichi Shinkai"

121 Publications

The fibronectin type-III (FNIII) domain of ATF7IP contributes to efficient transcriptional silencing mediated by the SETDB1 complex.

Epigenetics Chromatin 2020 11 30;13(1):52. Epub 2020 Nov 30.

Cellular Memory Laboratory, RIKEN Cluster for Pioneering Research, Wako, 351-0198, Japan.

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November 2020

H3K9 Demethylases JMJD1A and JMJD1B Control Prospermatogonia to Spermatogonia Transition in Mouse Germline.

Stem Cell Reports 2020 08 16;15(2):424-438. Epub 2020 Jul 16.

Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan; Institute of Advanced Medical Sciences, Tokushima University, 3-18-15 Kuramoto-cho, Tokushima, Tokushima 770-8503, Japan. Electronic address:

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August 2020

SETDB1-Mediated Silencing of Retroelements.

Viruses 2020 05 30;12(6). Epub 2020 May 30.

Cellular Memory Laboratory, RIKEN Cluster for Pioneering Research, RIKEN, Wako 351-0198, Japan.

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May 2020

G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development.

Bone 2020 08 25;137:115332. Epub 2020 Apr 25.

Department of Pharmacology, Tsurumi University School of Dental Medicine, Kanagawa 230-8501, Japan; Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan. Electronic address:

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August 2020

ATF7IP regulates SETDB1 nuclear localization and increases its ubiquitination.

EMBO Rep 2019 12 2;20(12):e48297. Epub 2019 Oct 2.

Cellular Memory Laboratory, Cluster for Pioneering Research, RIKEN, Wako, Japan.

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December 2019

Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection.

Cell Rep 2019 04;27(1):282-293.e4

Division of Epigenomics and Development, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan. Electronic address:

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April 2019

Histone H1 quantity determines the efficiency of chromatin condensation in both apoptotic and live cells.

Biochem Biophys Res Commun 2019 04 14;512(2):202-207. Epub 2019 Mar 14.

Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, 278-0022, Japan. Electronic address:

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April 2019

G9a-dependent histone methylation can be induced in G1 phase of cell cycle.

Sci Rep 2019 01 30;9(1):956. Epub 2019 Jan 30.

Cellular Memory Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.

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January 2019

Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation.

Structure 2019 03 10;27(3):485-496.e7. Epub 2019 Jan 10.

Graduate School of Medical Life Science, Yokohama City University, Yokohama 230-0045, Japan; JST, PRESTO, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan. Electronic address:

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March 2019

Intestinal F-box protein regulates quick avoidance behavior of Caenorhabditis elegans to the pathogenic bacterium Pseudomonas aeruginosa.

Genes Cells 2019 Mar 28;24(3):192-201. Epub 2019 Jan 28.

Molecular Neurobiology Research Group and DAILAB, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.

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March 2019

Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8.

Epigenetics Chromatin 2018 10 4;11(1):56. Epub 2018 Oct 4.

Cellular Memory Laboratory, RIKEN Cluster for Pioneering Research, Wako, 351-0198, Japan.

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October 2018

The Fab fragment of anti-IgE Cε2 domain prevents allergic reactions through interacting with IgE-FcεRIα complex on rat mast cells.

Sci Rep 2018 09 24;8(1):14237. Epub 2018 Sep 24.

Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan.

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September 2018

EOR-1 mediates non-cell autonomous regulation of abts-1 gene expression in HSNs​.

MicroPubl Biol 2018 Jul 12;2018. Epub 2018 Jul 12.

Molecular Neurobiology Research Group and DAILAB, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 6, 1-1-1, Higashi, Tsukuba, Ibaraki, 305-8566, Japan.

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July 2018

Regulation of chromatin states and gene expression during HSN neuronal maturation is mediated by EOR-1/PLZF, MAU-2/cohesin loader, and SWI/SNF complex.

Sci Rep 2018 05 21;8(1):7942. Epub 2018 May 21.

Molecular Neurobiology Research Group and DAI-Lab, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1, Higashi, Tsukuba, Ibaraki, 305-8566, Japan.

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May 2018

A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells.

Genome Res 2018 06 4;28(6):846-858. Epub 2018 May 4.

Cellular Memory Laboratory, Cluster for Pioneering Research, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.

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June 2018

A Simple Method for Visualization of Locus-Specific H4K20me1 Modifications in Living Single Cells.

G3 (Bethesda) 2018 07 2;8(7):2249-2255. Epub 2018 Jul 2.

Molecular Neurobiology Research Group and DAI-Lab, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1, Higashi, Tsukuba, Ibaraki, 305-8566, Japan

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July 2018

Cutting Edge: The Histone Methyltransferase G9a Is Required for Silencing of Helper T Lineage-Associated Genes in Proliferating CD8 T Cells.

J Immunol 2018 06 2;200(12):3891-3896. Epub 2018 May 2.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110; and

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June 2018

A somatic role for the histone methyltransferase Setdb1 in endogenous retrovirus silencing.

Nat Commun 2018 04 27;9(1):1683. Epub 2018 Apr 27.

Cellular Memory Laboratory, Cluster for Pioneering Research, RIKEN, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.

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April 2018

Combined Loss of JMJD1A and JMJD1B Reveals Critical Roles for H3K9 Demethylation in the Maintenance of Embryonic Stem Cells and Early Embryogenesis.

Stem Cell Reports 2018 04 8;10(4):1340-1354. Epub 2018 Mar 8.

Institute of Advanced Medical Sciences, Tokushima University, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan; Experimental Research Center for Infectious Diseases, Institute for Virus Research, Kyoto University, 53 Shogoin, Kawara-cho, Sakyo-ku, Kyoto 606-8597, Japan. Electronic address:

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April 2018

Biochemical validation of EHMT1 missense mutations in Kleefstra syndrome.

J Hum Genet 2018 May 19;63(5):555-562. Epub 2018 Feb 19.

Cellular Memory Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.

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May 2018

Histone H3 Methylated at Arginine 17 Is Essential for Reprogramming the Paternal Genome in Zygotes.

Cell Rep 2017 Sep;20(12):2756-2765

RIKEN BioResource Center, Ibaraki 305-0074, Japan; Graduate School of Life and Environmental Sciences, University of Tsukuba, Ibaraki 305-8572, Japan; Center for Disease Biology and Integrative Medicine, Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan. Electronic address:

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September 2017