Yiyun Cheng

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Stimuli-Responsive Hydrogels with Antibacterial Activity Assembled from Guanosine, Aminoglycoside, and a Bifunctional Anchor.

Adv Healthc Mater 2020 Jan 9;9(2):e1901329. Epub 2019 Dec 9.

Department of Orthopaedics, Fengxian Hospital Affiliated to Anhui University of Science and Technology, Shanghai, 201499, China.

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http://dx.doi.org/10.1002/adhm.201901329DOI Listing
January 2020

A Coordinative Dendrimer Achieves Excellent Efficiency in Cytosolic Protein and Peptide Delivery.

Angew Chem Int Ed Engl 2019 Dec 21. Epub 2019 Dec 21.

South China University of Technology, Molecular Science and Engineering, Wushan Road 381, 510640, Guangzhou, CHINA.

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http://dx.doi.org/10.1002/anie.201914970DOI Listing
December 2019

Polymers for cytosolic protein delivery.

Biomaterials 2019 Oct 15;218:119358. Epub 2019 Jul 15.

South China Advanced Institute for Soft Matter Science and Technology, School of Molecular Science and Engineering, South China University of Technology, Guangzhou, 510640, China; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.119358DOI Listing
October 2019

Off-on switching of enzyme activity by near-infrared light-induced photothermal phase transition of nanohybrids.

Sci Adv 2019 08 21;5(8):eaaw4252. Epub 2019 Aug 21.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China.

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http://dx.doi.org/10.1126/sciadv.aaw4252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703869PMC
August 2019

Nanovaccine based on a protein-delivering dendrimer for effective antigen cross-presentation and cancer immunotherapy.

Biomaterials 2019 Jul 25;207:1-9. Epub 2019 Mar 25.

Institute of Institute of Functional Nano & Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu, 215123, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.03.037DOI Listing
July 2019

Fluorinated Polymer Mediated Transmucosal Peptide Delivery for Intravesical Instillation Therapy of Bladder Cancer.

Small 2019 Jun 10;15(25):e1900936. Epub 2019 May 10.

Department of Urology, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, 518000, China.

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http://dx.doi.org/10.1002/smll.201900936DOI Listing
June 2019

A boronic acid-rich dendrimer with robust and unprecedented efficiency for cytosolic protein delivery and CRISPR-Cas9 gene editing.

Sci Adv 2019 06 12;5(6):eaaw8922. Epub 2019 Jun 12.

Shanghai Key Laboratory of Regulatory Biology, East China Normal University, Shanghai 200241, China.

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http://dx.doi.org/10.1126/sciadv.aaw8922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561739PMC
June 2019

Melanin-like nanoparticles decorated with an autophagy-inducing peptide for efficient targeted photothermal therapy.

Biomaterials 2019 May 1;203:63-72. Epub 2019 Mar 1.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612193012
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http://dx.doi.org/10.1016/j.biomaterials.2019.02.023DOI Listing
May 2019

Silencing MicroRNA-155 Attenuates Kainic Acid-Induced Seizure by Inhibiting Microglia Activation.

Neuroimmunomodulation 2019 29;26(2):67-76. Epub 2019 Mar 29.

Fujian Provincial Key Laboratory of Neurodegenerative Diseases and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China,

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http://dx.doi.org/10.1159/000496344DOI Listing
March 2019

A Guanidinium-Rich Polymer for Efficient Cytosolic Delivery of Native Proteins.

Bioconjug Chem 2019 02 6;30(2):413-417. Epub 2018 Nov 6.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences , East China Normal University , Shanghai 200241 , P. R. China.

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http://pubs.acs.org/doi/10.1021/acs.bioconjchem.8b00753
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http://dx.doi.org/10.1021/acs.bioconjchem.8b00753DOI Listing
February 2019

One stone with two birds: Phytic acid-capped platinum nanoparticles for targeted combination therapy of bone tumors.

Biomaterials 2019 02 21;194:130-138. Epub 2018 Dec 21.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612183085
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http://dx.doi.org/10.1016/j.biomaterials.2018.12.024DOI Listing
February 2019

A pH-responsive hydrogel with potent antibacterial activity against both aerobic and anaerobic pathogens.

Biomater Sci 2019 Jan;7(2):581-584

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, P.R. China.

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http://dx.doi.org/10.1039/c8bm01211cDOI Listing
January 2019

A Carboxyl-Terminated Dendrimer Enables Osteolytic Lesion Targeting and Photothermal Ablation of Malignant Bone Tumors.

ACS Appl Mater Interfaces 2019 Jan 19;11(1):160-168. Epub 2018 Dec 19.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences , East China Normal University , Shanghai 200241 , P. R. China.

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http://dx.doi.org/10.1021/acsami.8b15827DOI Listing
January 2019

Fluoropolymers for intracellular and in vivo protein delivery.

Biomaterials 2018 11 9;182:167-175. Epub 2018 Aug 9.

South China Advanced Institute for Soft Matter Science and Technology, South China University of Technology, Guangzhou, 510640, PR China; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2018.08.023DOI Listing
November 2018

Multifunctional melanin-like nanoparticles for bone-targeted chemo-photothermal therapy of malignant bone tumors and osteolysis.

Biomaterials 2018 11 18;183:10-19. Epub 2018 Aug 18.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612183058
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http://dx.doi.org/10.1016/j.biomaterials.2018.08.033DOI Listing
November 2018

Foe to Friend: Supramolecular Nanomedicines Consisting of Natural Polyphenols and Bortezomib.

Nano Lett 2018 11 1;18(11):7045-7051. Epub 2018 Oct 1.

South China Advanced Institute for Soft Matter Science and Technology , South China University of Technology , Guangzhou 510640 , P.R. China.

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http://pubs.acs.org/doi/10.1021/acs.nanolett.8b03015
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http://dx.doi.org/10.1021/acs.nanolett.8b03015DOI Listing
November 2018

Green Tea Catechin Dramatically Promotes RNAi Mediated by Low-Molecular-Weight Polymers.

ACS Cent Sci 2018 Oct 19;4(10):1326-1333. Epub 2018 Sep 19.

Shanghai Key Laboratory of Regulatory Biology, East China Normal University, Shanghai 200241, China.

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http://pubs.acs.org/doi/10.1021/acscentsci.8b00363
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http://dx.doi.org/10.1021/acscentsci.8b00363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202644PMC
October 2018

Protective Role of L-3--Butylphthalide in Cognitive Function and Dysthymic Disorders in Mouse With Chronic Epilepsy.

Front Pharmacol 2018 11;9:734. Epub 2018 Jul 11.

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.3389/fphar.2018.00734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051017PMC
July 2018

A Self-Assembled Coumarin-Anchored Dendrimer for Efficient Gene Delivery and Light-Responsive Drug Delivery.

Biomacromolecules 2018 06 30;19(6):2194-2201. Epub 2018 Apr 30.

Shanghai Key Laboratory of Regulatory Biology , East China Normal University , Shanghai , 200241 , P. R. China.

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http://dx.doi.org/10.1021/acs.biomac.8b00246DOI Listing
June 2018

A Nanocomposite Hydrogel with Potent and Broad-Spectrum Antibacterial Activity.

ACS Appl Mater Interfaces 2018 May 23;10(17):15163-15173. Epub 2018 Apr 23.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences , East China Normal University , Shanghai 200241 , P. R. China.

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http://pubs.acs.org/doi/10.1021/acsami.8b02527
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http://dx.doi.org/10.1021/acsami.8b02527DOI Listing
May 2018

The fluorination effect of fluoroamphiphiles in cytosolic protein delivery.

Nat Commun 2018 04 10;9(1):1377. Epub 2018 Apr 10.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, China.

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http://dx.doi.org/10.1038/s41467-018-03779-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893556PMC
April 2018

Autophagy inhibition enabled efficient photothermal therapy at a mild temperature.

Biomaterials 2017 Oct 27;141:116-124. Epub 2017 Jun 27.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.06.030DOI Listing
October 2017

A Combination of Guanidyl and Phenyl Groups on a Dendrimer Enables Efficient siRNA and DNA Delivery.

Biomacromolecules 2017 Aug 17;18(8):2371-2378. Epub 2017 Jul 17.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University , Shanghai, 200241, P. R. China.

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http://dx.doi.org/10.1021/acs.biomac.7b00567DOI Listing
August 2017

Dynamic Softening or Stiffening a Supramolecular Hydrogel by Ultraviolet or Near-Infrared Light.

ACS Appl Mater Interfaces 2017 Jul 14;9(29):24511-24517. Epub 2017 Jul 14.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University , Shanghai 200241, P. R. China.

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http://dx.doi.org/10.1021/acsami.7b07204DOI Listing
July 2017

Dynamic Modulation of Enzyme Activity by Near-Infrared Light.

Angew Chem Int Ed Engl 2017 06 8;56(24):6767-6772. Epub 2017 May 8.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, China.

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http://dx.doi.org/10.1002/anie.201700968DOI Listing
June 2017

Fabrication of Low-Generation Dendrimers into Nanostructures for Efficient and Nontoxic Gene Delivery.

Top Curr Chem (Cham) 2017 Jun 29;375(3):62. Epub 2017 May 29.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, People's Republic of China.

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http://dx.doi.org/10.1007/s41061-017-0151-6DOI Listing
June 2017

Rational Design of a Polymer with Robust Efficacy for Intracellular Protein and Peptide Delivery.

Nano Lett 2017 03 20;17(3):1678-1684. Epub 2017 Feb 20.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University , Shanghai 200241, P. R. China.

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http://dx.doi.org/10.1021/acs.nanolett.6b04955DOI Listing
March 2017

A smart aminoglycoside hydrogel with tunable gel degradation, on-demand drug release, and high antibacterial activity.

J Control Release 2017 02 7;247:145-152. Epub 2017 Jan 7.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2017.01.003DOI Listing
February 2017

A thermo-degradable hydrogel with light-tunable degradation and drug release.

Biomaterials 2017 01 11;112:133-140. Epub 2016 Oct 11.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.10.015DOI Listing
January 2017

Osteotropic peptide-mediated bone targeting for photothermal treatment of bone tumors.

Biomaterials 2017 01 9;114:97-105. Epub 2016 Nov 9.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612163061
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http://dx.doi.org/10.1016/j.biomaterials.2016.11.010DOI Listing
January 2017

Structure-activity relationships of fluorinated dendrimers in DNA and siRNA delivery.

Acta Biomater 2016 12 20;46:204-210. Epub 2016 Sep 20.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2016.09.023DOI Listing
December 2016

How can we use dendrimer-templated ultrasmall and multifunctional nanoparticles in photothermal cancer therapy?

Nanomedicine (Lond) 2016 12 15;11(24):3181-3183. Epub 2016 Nov 15.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China.

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http://dx.doi.org/10.2217/nnm-2016-0359DOI Listing
December 2016

Injectable and responsively degradable hydrogel for personalized photothermal therapy.

Biomaterials 2016 10 12;104:129-37. Epub 2016 Jul 12.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.07.013DOI Listing
October 2016

Bone and metal targeted polymeric nanoparticles (US20150125391 A1): a patent evaluation.

Expert Opin Ther Pat 2016 Sep 25;26(9):987-91. Epub 2016 Jul 25.

b Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences , East China Normal University , Shanghai , P.R. China.

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http://dx.doi.org/10.1080/13543776.2016.1212840DOI Listing
September 2016

Transdermal delivery of therapeutic agents using dendrimers (US20140018435A1): a patent evaluation.

Expert Opin Ther Pat 2015 6;25(10):1209-14. Epub 2015 Jul 6.

a East China Normal University, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences , Shanghai, 200241, PR China

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http://dx.doi.org/10.1517/13543776.2015.1044974DOI Listing
May 2016

Tailoring the dendrimer core for efficient gene delivery.

Acta Biomater 2016 Apr 23;35:1-11. Epub 2016 Feb 23.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2016.02.031DOI Listing
April 2016

Dendrimer-Templated Ultrasmall and Multifunctional Photothermal Agents for Efficient Tumor Ablation.

ACS Nano 2016 04 11;10(4):4863-72. Epub 2016 Apr 11.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University , Shanghai 200241, People's Republic of China.

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http://dx.doi.org/10.1021/acsnano.6b02058DOI Listing
April 2016

Screening of efficient siRNA carriers in a library of surface-engineered dendrimers.

Sci Rep 2016 04 28;6:25069. Epub 2016 Apr 28.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, P. R. China.

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http://dx.doi.org/10.1038/srep25069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848513PMC
April 2016

Multi-responsive photothermal-chemotherapy with drug-loaded melanin-like nanoparticles for synergetic tumor ablation.

Biomaterials 2016 Mar 12;81:114-124. Epub 2015 Dec 12.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.11.037DOI Listing
March 2016

Temperature-Responsive Gene Silencing by a Smart Polymer.

Bioconjug Chem 2016 Mar 26;27(3):495-9. Epub 2016 Jan 26.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University , Shanghai, 200241, P.R. China.

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http://dx.doi.org/10.1021/acs.bioconjchem.5b00666DOI Listing
March 2016

Clustering Small Dendrimers into Nanoaggregates for Efficient DNA and siRNA Delivery with Minimal Toxicity.

Adv Healthc Mater 2016 Mar 20;5(5):584-92. Epub 2016 Jan 20.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, P. R. China.

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http://dx.doi.org/10.1002/adhm.201500679DOI Listing
March 2016

Stimuli-responsive dendrimers in drug delivery.

Biomater Sci 2016 Mar;4(3):375-90

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China.

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http://xlink.rsc.org/?DOI=C5BM00532A
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http://dx.doi.org/10.1039/c5bm00532aDOI Listing
March 2016

Being Two Is Better than Being One: A Facile Strategy to Fabricate Multicomponent Nanoparticles for Efficient Gene Delivery.

Bioconjug Chem 2016 Mar 5;27(3):638-46. Epub 2016 Feb 5.

Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University , Shanghai 200241, China.

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http://dx.doi.org/10.1021/acs.bioconjchem.5b00643DOI Listing
March 2016

A Facile Strategy to Prepare Dendrimer-stabilized Gold Nanorods with Sub-10-nm Size for Efficient Photothermal Cancer Therapy.

Sci Rep 2016 Mar 9;6:22764. Epub 2016 Mar 9.

Shanghai Key Laboratory of Regulatory Biology, School of Life sciences, East China Normal University, Shanghai, 200241, P.R. China.

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http://dx.doi.org/10.1038/srep22764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783698PMC
March 2016

Structure-activity relationship of dendrimers engineered with twenty common amino acids in gene delivery.

Acta Biomater 2016 Jan 23;29:94-102. Epub 2015 Oct 23.

Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2015.10.034DOI Listing
January 2016

Near infrared light-responsive and injectable supramolecular hydrogels for on-demand drug delivery.

Chem Commun (Camb) 2016 Jan;52(5):978-81

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, P. R. China.

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http://dx.doi.org/10.1039/c5cc08391eDOI Listing
January 2016

Nucleobase-modified dendrimers as nonviral vectors for efficient and low cytotoxic gene delivery.

Colloids Surf B Biointerfaces 2015 Dec 21;136:1148-55. Epub 2015 Nov 21.

Department of Orthopedic Oncology, Changzheng Hospital, The Second Military Medical University, Shanghai, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.colsurfb.2015.11.015DOI Listing
December 2015

A fluorinated dendrimer achieves excellent gene transfection efficacy at extremely low nitrogen to phosphorus ratios.

Nat Commun 2014 ;5:3053

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China.

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http://www.nature.com/articles/ncomms4053
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http://dx.doi.org/10.1038/ncomms4053DOI Listing
November 2015

Self-Assembled Fluorodendrimers Combine the Features of Lipid and Polymeric Vectors in Gene Delivery.

Angew Chem Int Ed Engl 2015 Sep 10;54(40):11647-51. Epub 2015 Aug 10.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai (China).

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http://dx.doi.org/10.1002/anie.201501461DOI Listing
September 2015

Triggered release of anticancer drugs from PEGylated polydopamine nanospheres by near-infrared light.

J Control Release 2015 Sep 19;213:e122. Epub 2015 Aug 19.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2015.05.205DOI Listing
September 2015

Self-assembled fluorodendrimers allow efficient transfection with ultra-low DNA dose.

J Control Release 2015 Sep 19;213:e42. Epub 2015 Aug 19.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2015.05.068DOI Listing
September 2015

Catechol-grafted dendrimer with a neutral shell allows pH-triggered "off-on" release of bortezomib.

J Control Release 2015 Sep 19;213:e78-9. Epub 2015 Aug 19.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2015.05.130DOI Listing
September 2015

Improving gene transfection efficacy of low generation dendrimers through specific hydrogen-bond recognition.

J Control Release 2015 Sep 19;213:e82-3. Epub 2015 Aug 19.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2015.05.137DOI Listing
September 2015

Polymers modified with double-tailed fluorous compounds for efficient DNA and siRNA delivery.

Acta Biomater 2015 Aug 1;22:111-9. Epub 2015 May 1.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2015.04.037DOI Listing
August 2015

Surface-engineered dendrimers in gene delivery.

Chem Rev 2015 Jun 6;115(11):5274-300. Epub 2015 May 6.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, P. R. China.

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http://dx.doi.org/10.1021/cr500542tDOI Listing
June 2015

A supramolecular approach to improve the gene transfection efficacy of dendrimers.

Chem Commun (Camb) 2015 Jun;51(47):9741-3

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, P. R. China.

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http://dx.doi.org/10.1039/c5cc02300aDOI Listing
June 2015

Trifolium-like Platinum Nanoparticle-Mediated Photothermal Therapy Inhibits Tumor Growth and Osteolysis in a Bone Metastasis Model.

Small 2015 May 8;11(17):2080-6. Epub 2015 Jan 8.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200062, P. R. China.

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http://dx.doi.org/10.1002/smll.201403315DOI Listing
May 2015

Triazine-modified dendrimer for efficient TRAIL gene therapy in osteosarcoma.

Acta Biomater 2015 Apr 14;17:115-24. Epub 2015 Jan 14.

Department of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S17427061150000
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http://dx.doi.org/10.1016/j.actbio.2015.01.007DOI Listing
April 2015

Tumor extracellular acidity activated "off-on" release of bortezomib from a biocompatible dendrimer.

Biomater Sci 2015 Mar 18;3(3):480-9. Epub 2014 Dec 18.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, P. R. China.

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http://xlink.rsc.org/?DOI=C4BM00365A
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http://dx.doi.org/10.1039/c4bm00365aDOI Listing
March 2015

Hydrogen-bonding dramatically modulates the gene transfection efficacy of surface-engineered dendrimers.

Biomater Sci 2015 Mar 22;3(3):500-8. Epub 2014 Dec 22.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, P.R. China.

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http://dx.doi.org/10.1039/c4bm00335gDOI Listing
March 2015

Evidence of guest encapsulation within G8 and G10 dendrimers using NMR techniques.

Soft Matter 2014 Dec;10(45):9153-8

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, P.R. China.

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http://dx.doi.org/10.1039/c4sm01381fDOI Listing
December 2014

Synergistic effect of amino acids modified on dendrimer surface in gene delivery.

Biomaterials 2014 Nov 8;35(33):9187-98. Epub 2014 Aug 8.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.07.027DOI Listing
November 2014

The effect of fluorination on the transfection efficacy of surface-engineered dendrimers.

Biomaterials 2014 Aug 10;35(24):6603-13. Epub 2014 May 10.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.04.065DOI Listing
August 2014

Fluorinated poly(propylenimine) dendrimers as gene vectors.

Biomaterials 2014 Jul 6;35(20):5407-5413. Epub 2014 Apr 6.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.03.040DOI Listing
July 2014

Dendrimer-surfactant interactions.

Soft Matter 2014 Apr;10(16):2714-27

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, People's Republic of China.

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http://dx.doi.org/10.1039/c3sm53180eDOI Listing
April 2014

Poly(amidoamine) and poly(propyleneimine) dendrimers show distinct binding behaviors with sodium dodecyl sulfate: insights from SAXS and NMR analysis.

J Phys Chem B 2014 Mar 7;118(11):3074-84. Epub 2014 Mar 7.

China Institute of Atomic Energy, Beijing 102413, People's Republic of China.

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http://pubs.acs.org/doi/10.1021/jp412660p
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March 2014

Paramagnetic NMR investigation of dendrimer-based host-guest interactions.

PLoS One 2013 10;8(6):e64722. Epub 2013 Jun 10.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064722PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677888PMC
February 2014

Surface-engineered dendrimers with a diaminododecane core achieve efficient gene transfection and low cytotoxicity.

Bioconjug Chem 2014 Feb 21;25(2):342-50. Epub 2014 Jan 21.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University , Shanghai, 200241, P.R. China.

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http://dx.doi.org/10.1021/bc400496uDOI Listing
February 2014

Glutathione-triggered "off-on" release of anticancer drugs from dendrimer-encapsulated gold nanoparticles.

J Am Chem Soc 2013 Jul 21;135(26):9805-10. Epub 2013 Jun 21.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200062, P.R. China.

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http://dx.doi.org/10.1021/ja402903hDOI Listing
July 2013

Dendrimer and cancer: a patent review (2006-present).

Expert Opin Ther Pat 2013 Apr 23;23(4):515-29. Epub 2013 Jan 23.

East China Normal University, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Shanghai, PR China.

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http://dx.doi.org/10.1517/13543776.2013.761207DOI Listing
April 2013

Generation 9 polyamidoamine dendrimer encapsulated platinum nanoparticle mimics catalase size, shape, and catalytic activity.

Langmuir 2013 Apr 15;29(17):5262-70. Epub 2013 Apr 15.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200062, People's Republic of China.

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http://dx.doi.org/10.1021/la3046077DOI Listing
April 2013

Polyamidoamine dendronized hollow fiber membranes in the recovery of heavy metal ions.

ACS Appl Mater Interfaces 2013 Mar 8;5(6):1907-12. Epub 2013 Mar 8.

CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui, 230026, People's Republic of China.

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http://dx.doi.org/10.1021/am400155bDOI Listing
March 2013

Reducing cytotoxicity while improving anti-cancer drug loading capacity of polypropylenimine dendrimers by surface acetylation.

Acta Biomater 2012 Dec 27;8(12):4304-13. Epub 2012 Jul 27.

Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China.

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http://dx.doi.org/10.1016/j.actbio.2012.07.031DOI Listing
December 2012

Disulfide cross-linked low generation dendrimers with high gene transfection efficacy, low cytotoxicity, and low cost.

J Am Chem Soc 2012 Oct 10;134(42):17680-7. Epub 2012 Oct 10.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China.

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http://dx.doi.org/10.1021/ja307290jDOI Listing
October 2012

Host-guest chemistry of dendrimer-cyclodextrin conjugates: selective encapsulations of guests within dendrimer or cyclodextrin cavities revealed by NOE NMR techniques.

J Phys Chem B 2012 Sep 30;116(36):11217-24. Epub 2012 Aug 30.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China.

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http://dx.doi.org/10.1021/jp3062916DOI Listing
September 2012

NMR insights into dendrimer-based host-guest systems.

Chem Rev 2012 Jul 9;112(7):3856-91. Epub 2012 Apr 9.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, People's Republic of China.

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http://pubs.acs.org/doi/10.1021/cr200333h
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July 2012

Interactions between dendrimers and ionic liquids revealed by pulsed field gradient and nuclear Overhauser effect NMR studies.

J Phys Chem B 2012 Jun 31;116(24):7203-12. Epub 2012 May 31.

CAS Key Laboratory of Soft Matter Chemistry, School of Chemistry and Material Science, University of Science and Technology of China, Hefei, Anhui 230026, People’s Republic of China.

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http://dx.doi.org/10.1021/jp303391cDOI Listing
June 2012

Fast screening of dendrimer-binding compounds by diffusion NMR techniques.

J Phys Chem B 2012 May 2;116(18):5398-405. Epub 2012 May 2.

Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, PR China.

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http://dx.doi.org/10.1021/jp302731uDOI Listing
May 2012

Poly(amidoamine) dendronized hollow fiber membranes: synthesis, characterization, and preliminary applications as drug delivery devices.

Acta Biomater 2012 Mar 2;8(3):1316-22. Epub 2011 Dec 2.

Laboratory of Functional Membranes, Department of Chemistry, University of Science and Technology of China, Hefei 230026, Anhui, People's Republic of China.

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http://dx.doi.org/10.1016/j.actbio.2011.11.027DOI Listing
March 2012

Host-guest chemistry of dendrimer-drug complexes: 7. Formation of stable inclusions between acetylated dendrimers and drugs bearing multiple charges.

J Phys Chem B 2012 Mar 1;116(10):3075-82. Epub 2012 Mar 1.

CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, People's Republic of China.

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http://dx.doi.org/10.1021/jp211384pDOI Listing
March 2012

Design of interior-functionalized fully acetylated dendrimers for anticancer drug delivery.

Biomaterials 2011 Dec 22;32(36):9950-9. Epub 2011 Sep 22.

Department of Chemistry, University of Science and Technology of China, Hefei 230026, PR China.

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http://dx.doi.org/10.1016/j.biomaterials.2011.09.016DOI Listing
December 2011

Understanding the binding interactions between dendrimer and 18 common amino acids by NMR techniques.

J Phys Chem B 2011 Nov 7;115(44):12728-35. Epub 2011 Oct 7.

School of Life Sciences, East China Normal University, Shanghai, PR China.

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http://dx.doi.org/10.1021/jp207817fDOI Listing
November 2011

Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives.

Chem Soc Rev 2011 May 1;40(5):2673-703. Epub 2011 Feb 1.

School of Life Sciences, East China Normal University, Shanghai, 200062, People's Republic of China.

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http://dx.doi.org/10.1039/c0cs00097cDOI Listing
May 2011

Organic-inorganic hybrid anion exchange hollow fiber membranes: a novel device for drug delivery.

Int J Pharm 2011 Apr 1;408(1-2):39-49. Epub 2011 Feb 1.

CAS Key Laboratory of Soft Matter Chemistry, Lab of Functional Membranes, School of Chemistry and Material Science, University of Science and Technology of China, Hefei 230026, PR China.

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http://dx.doi.org/10.1016/j.ijpharm.2011.01.046DOI Listing
April 2011

Stimuli response of cystamine-core dendrimer revealed by diffusion and NOE NMR studies.

J Phys Chem B 2011 Apr 18;115(14):3777-83. Epub 2011 Mar 18.

CAS Key Laboratory of Soft Matter Chemistry, School of Chemistry and Material Science, University of Science and Technology of China, Hefei, Anhui, 230026, People's Republic of China.

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http://dx.doi.org/10.1021/jp2003613DOI Listing
April 2011

Host-guest chemistry of dendrimer-drug complexes. 6. Fully acetylated dendrimers as biocompatible drug vehicles using dexamethasone 21-phosphate as a model drug.

J Phys Chem B 2011 Mar 22;115(10):2185-95. Epub 2011 Feb 22.

CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, People’s Republic of China.

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http://dx.doi.org/10.1021/jp111044kDOI Listing
March 2011

Host-guest chemistry of dendrimer-drug complexes. 5. Insights into the design of formulations for noninvasive delivery of heparin revealed by isothermal titration calorimetry and NMR studies.

J Phys Chem B 2010 Sep;114(34):11017-26

CAS Key Laboratory of Soft Matter Chemistry, School of Chemistry and Material Science, University of Science and Technology of China, Hefei, Anhui, 230026, People's Republic of China.

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http://dx.doi.org/10.1021/jp105958jDOI Listing
September 2010

High-throughput screening of dendrimer-binding drugs.

J Am Chem Soc 2010 Sep;132(38):13182-4

CAS Key Laboratory of Soft Matter Chemistry, School of Chemistry and Material Science, University of Science and Technology of China, Hefei, Anhui 230026, People's Republic of China.

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http://pubs.acs.org/doi/abs/10.1021/ja106128u
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September 2010

Host-guest chemistry of dendrimer-drug complexes. 4. An in-depth look into the binding/encapsulation of guanosine monophosphate by dendrimers.

J Phys Chem B 2010 Jun;114(21):7148-57

CAS Key Laboratory of Soft Matter Chemistry, School of Chemistry and Material Science, University of Science and Technology of China, Hefei, Anhui, 230026, People's Republic of China.

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http://dx.doi.org/10.1021/jp1007889DOI Listing
June 2010

Insights into the interactions between dendrimers and multiple surfactants: 5. Formation of miscellaneous mixed micelles revealed by a combination of 1H NMR, diffusion, and NOE analysis.

J Phys Chem B 2010 Jun;114(21):7265-73

CAS Key Laboratory of Soft Matter Chemistry, School of Chemistry and Material Science, University of Science and Technology of China, Hefei, Anhui, 230026, People's Republic of China.

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http://pubs.acs.org/doi/abs/10.1021/jp1026493
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June 2010

New insights into interactions between dendrimers and surfactants. 4. Fast-exchange/slow-exchange transitions in the structure of dendrimer-surfactant aggregates.

J Phys Chem B 2010 May;114(18):6048-55

CAS Key Laboratory of Soft Matter Chemistry, School of Chemistry and Material Science, University of Science and Technology of China, Hefei, Anhui, 230026, People's Republic of China.

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http://dx.doi.org/10.1021/jp100805uDOI Listing
May 2010

Insights into the interactions between dendrimers and bioactive surfactants: 3. Size-dependent and hydrophobic property-dependent encapsulation of bile salts.

J Phys Chem B 2009 Oct;113(39):12934-43

Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, PR China.

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http://pubs.acs.org/doi/abs/10.1021/jp906661z
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October 2009

Host-guest chemistry of dendrimer-drug complexes. 3. Competitive binding of multiple drugs by a single dendrimer for combination therapy.

J Phys Chem B 2009 Oct;113(43):14172-9

Laboratory of Functional Membranes, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, PR China.

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http://dx.doi.org/10.1021/jp907437eDOI Listing
October 2009

Host-guest chemistry of dendrimer-drug complexes. 2. Effects of molecular properties of guests and surface functionalities of dendrimers.

J Phys Chem B 2009 Aug;113(31):10650-9

Laboratory of Functional Membranes, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P.R. China.

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http://pubs.acs.org/doi/abs/10.1021/jp9047055
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August 2009

New insights into the interactions between dendrimers and surfactants: 2. Design of new drug formulations based on dendrimer-surfactant aggregates.

J Phys Chem B 2009 Jun;113(24):8339-46

Laboratory of Functional Membranes, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, People's Republic of China.

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http://dx.doi.org/10.1021/jp9021618DOI Listing
June 2009

Host-guest chemistry and physicochemical properties of the dendrimer-mycophenolic acid complex.

J Phys Chem B 2009 Jan;113(1):64-74

Department of Chemistry, University of Science and Technology of China, Hefei, 230026, Anhui, People's Republic of China.

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http://dx.doi.org/10.1021/jp8078919DOI Listing
January 2009