Yiying Zhang

Yiying Zhang

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Yiying Zhang

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Induction of an MLKL mediated non-canonical necroptosis through reactive oxygen species by tanshinol A in lung cancer cells.

Biochem Pharmacol 2019 Nov 1;171:113684. Epub 2019 Nov 1.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, China. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2019.113684DOI Listing
November 2019

Synthesis and Properties of Energetic Hydrazinium 5-Nitro-3-dinitromethyl-2-pyrazole by Unexpected Isomerization of -Nitropyrazole.

ACS Omega 2019 Nov 7;4(21):19011-19017. Epub 2019 Nov 7.

School of Materials Science & Engineering, Beijing Institute of Technology, Beijing 100081, China.

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http://dx.doi.org/10.1021/acsomega.9b01910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868590PMC
November 2019

MiR-32-5p influences high glucose-induced cardiac fibroblast proliferation and phenotypic alteration by inhibiting DUSP1.

BMC Mol Biol 2019 08 22;20(1):21. Epub 2019 Aug 22.

Department of Cardiology, Children's Hospital, Zhejiang University School of Medicine, No. 3333 Binsheng Road, Binjiang District, Hangzhou, 310051, Zhejiang, China.

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http://dx.doi.org/10.1186/s12867-019-0135-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704591PMC
August 2019

Acute Fasting Does Not Induce Cognitive Impairment in Mice.

Front Neurosci 2019 26;13:896. Epub 2019 Aug 26.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, United States.

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https://www.frontiersin.org/article/10.3389/fnins.2019.00896
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http://dx.doi.org/10.3389/fnins.2019.00896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718131PMC
August 2019

MiR-150-5p retards the progression of myocardial fibrosis by targeting .

Cell Cycle 2019 Jun 23;18(12):1335-1348. Epub 2019 May 23.

a Department of Cardiology , Children's Hospital, Zhejiang University School of Medicine , Hangzhou , Zhejiang , PR China.

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http://dx.doi.org/10.1080/15384101.2019.1617614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592234PMC
June 2019

Development of a monoclonal antibody against swine leukocyte antigen (SLA)-DR α chain and evaluation of SLA-DR expression in bone marrow-derived dendritic cells after PRRSV infection.

Vet Immunol Immunopathol 2019 May 11;211:19-24. Epub 2019 Apr 11.

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, 712100, China; Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, Yangling, Shaanxi, 712100, China. Electronic address:

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http://dx.doi.org/10.1016/j.vetimm.2019.04.001DOI Listing
May 2019

Sevoflurane induces cognitive impairment in young mice via autophagy.

PLoS One 2019 20;14(5):e0216372. Epub 2019 May 20.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0216372PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527218PMC
May 2019

A new scoring system to predict Kawasaki disease with coronary artery lesions.

Clin Rheumatol 2019 Apr 6;38(4):1099-1107. Epub 2018 Dec 6.

Department of Cardiology, Children's Hospital, Zhejiang University School of Medicine, No. 3333, Binsheng Road, Hangzhou, 310052, People's Republic of China.

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http://dx.doi.org/10.1007/s10067-018-4393-7DOI Listing
April 2019

Inhibition of endogenous hydrogen sulfide production improves viral elimination in CVB3-infected myocardium in mice.

Pediatr Res 2019 03 16;85(4):533-538. Epub 2019 Jan 16.

Children's Hospital, Zhejiang University School of Medicine, No. 3333, Binsheng Road, 310052, Hangzhou, China.

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http://dx.doi.org/10.1038/s41390-019-0281-3DOI Listing
March 2019

Geographical variation in lung cancer risk associated with road traffics in Jiading District, Shanghai.

Sci Total Environ 2019 Feb 22;652:729-735. Epub 2018 Oct 22.

Fudan University School of Public Health, Building 8, 130 Dong'an Road, Xuhui District, Shanghai 200032, China; Key Laboratory of Public Health Safety, Fudan University, Ministry of Education, Building 8, 130 Dong An Road, Xuhui District, Shanghai 200032, China; Fudan University Center for Tropical Disease Research, Building 8, 130 Dong'an Road, Xuhui District, Shanghai 200032, China. Electronic address:

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http://dx.doi.org/10.1016/j.scitotenv.2018.10.266DOI Listing
February 2019

Energetic C-trinitromethyl-substituted pyrazoles: synthesis and characterization.

Dalton Trans 2019 Jan;48(4):1524-1529

Xi'an Modern Chemistry Research Institute, Xi'an 710065, China.

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http://dx.doi.org/10.1039/c8dt04712jDOI Listing
January 2019

ILDR2 has a negligible role in hepatic steatosis.

PLoS One 2018 30;13(5):e0197548. Epub 2018 May 30.

Naomi Berrie Diabetes Center and Division of Molecular Genetics, Department of Pediatrics, Columbia University, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197548PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976177PMC
December 2018

Weight Cycling Increases Longevity Compared with Sustained Obesity in Mice.

Obesity (Silver Spring) 2018 11;26(11):1733-1739

Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1002/oby.22290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221135PMC
November 2018

Folate, Vitamin B6 and Vitamin B12 Intake in Relation to Hyperuricemia.

J Clin Med 2018 Aug 11;7(8). Epub 2018 Aug 11.

School of Public Health, Jiamusi University, Jiamusi 154007, China.

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http://dx.doi.org/10.3390/jcm7080210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111262PMC
August 2018

Anesthetic Isoflurane or Desflurane Plus Surgery Differently Affects Cognitive Function in Alzheimer's Disease Transgenic Mice.

Mol Neurobiol 2018 Jul 6;55(7):5623-5638. Epub 2017 Oct 6.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Room 4310, Charlestown, MA, 02129-2060, USA.

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http://dx.doi.org/10.1007/s12035-017-0787-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889364PMC
July 2018

The role of Rpgrip1l, a component of the primary cilium, in adipocyte development and function.

FASEB J 2018 07 21;32(7):3946-3956. Epub 2018 Feb 21.

Naomi Berrie Diabetes Center, Columbia University Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1096/fj.201701216RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998974PMC
July 2018

Association between Dietary Zinc Intake and Hyperuricemia among Adults in the United States.

Nutrients 2018 May 5;10(5). Epub 2018 May 5.

School of Public Health, Jiamusi University, Jiamusi 154007, China.

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http://dx.doi.org/10.3390/nu10050568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986448PMC
May 2018

Dietary Magnesium Intake and Hyperuricemia among US Adults.

Nutrients 2018 Mar 2;10(3). Epub 2018 Mar 2.

Department of Epidemiology, School of Public Health, Harbin Medical University, Harbin 150081, China.

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http://dx.doi.org/10.3390/nu10030296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872714PMC
March 2018

Anesthesia/Surgery Induces Cognitive Impairment in Female Alzheimer's Disease Transgenic Mice.

J Alzheimers Dis 2017 ;57(2):505-518

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.

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http://dx.doi.org/10.3233/JAD-161268DOI Listing
February 2018

Sevoflurane Acts on Ubiquitination-Proteasome Pathway to Reduce Postsynaptic Density 95 Protein Levels in Young Mice.

Anesthesiology 2017 12;127(6):961-975

From the Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (H.L., B.Y.); Department of Anesthesia, Critical Care and Medicine (H.L., N.L., Y.D., G.X., Y.Z., L.S., Z.X.) and Massachusetts General Hospital Biostatistics Center (H.Z.), Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China (N.L.); First Affiliated Hospital, Anhui Medical University, Hefei, China (G.X.); School of Medicine and Health Sciences, George Washington University, Washington, D.C. (L.S.); and Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts (S.G.S.).

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http://dx.doi.org/10.1097/ALN.0000000000001889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685882PMC
December 2017

Energetic Di- and Trinitromethylpyridines: Synthesis and Characterization.

Molecules 2017 Dec 21;23(1). Epub 2017 Dec 21.

School of Material Science & Engineering, Beijing Institute of Technology, Beijing 100081, China.

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http://dx.doi.org/10.3390/molecules23010002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943950PMC
December 2017

Leptin Function and Regulation.

Compr Physiol 2017 12 12;8(1):351-369. Epub 2017 Dec 12.

Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, New York, USA.

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http://dx.doi.org/10.1002/cphy.c160041DOI Listing
December 2017

A new model to predict intravenous immunoglobin-resistant Kawasaki disease.

Oncotarget 2017 Oct 19;8(46):80722-80729. Epub 2017 Sep 19.

Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, PR China.

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http://dx.doi.org/10.18632/oncotarget.21083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655234PMC
October 2017

Anesthesia and Surgery Impair Blood-Brain Barrier and Cognitive Function in Mice.

Front Immunol 2017 9;8:902. Epub 2017 Aug 9.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United States.

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http://dx.doi.org/10.3389/fimmu.2017.00902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552714PMC
August 2017

Anesthetic Isoflurane Induces DNA Damage Through Oxidative Stress and p53 Pathway.

Mol Neurobiol 2017 07 19;54(5):3591-3605. Epub 2016 May 19.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 149 13th St., Room 4310, Charlestown, MA, 02129, USA.

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http://dx.doi.org/10.1007/s12035-016-9937-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736399PMC
July 2017

Anesthetic Sevoflurane Causes Rho-Dependent Filopodial Shortening in Mouse Neurons.

PLoS One 2016 21;11(7):e0159637. Epub 2016 Jul 21.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159637PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956198PMC
July 2017

Notch4 signaling pathway in a Kawasaki disease mouse model induced by cell wall extract.

Exp Ther Med 2017 Jun 5;13(6):3438-3442. Epub 2017 May 5.

Department of Cardiology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, P.R. China.

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http://dx.doi.org/10.3892/etm.2017.4434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450570PMC
June 2017

Notch4 Signaling Pathway of Endothelial Progenitor Cells in a Kawasaki Disease Model Induced by Lactobacillus casei Cell Wall Extract.

J Vasc Res 2016 24;53(5-6):340-348. Epub 2016 Dec 24.

The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, PR China.

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http://dx.doi.org/10.1159/000449061DOI Listing
May 2017

Predictors for intravenous immunoglobulin resistance and coronary artery lesions in Kawasaki disease.

Pediatr Rheumatol Online J 2017 Mar 21;15(1):17. Epub 2017 Mar 21.

Children's Hospital, Zhejiang University School of Medicine, No.57, Zhugan Lane, Hangzhou, 310003, People's Republic of China.

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http://dx.doi.org/10.1186/s12969-017-0149-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359815PMC
March 2017

Neurodegeneration: Etiologies and New Therapies 2016.

Biomed Res Int 2016 3;2016:8363179. Epub 2016 Nov 3.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1155/2016/8363179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112315PMC
February 2017

Mild Hypothermia Attenuates the Anesthetic Isoflurane-Induced Cytotoxicity.

Front Cell Neurosci 2017 8;11:15. Epub 2017 Feb 8.

Shanghai Tenth People's Hospital, Tongji University School of MedicineShanghai, China; Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical SchoolCharlestown, MA, USA.

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http://dx.doi.org/10.3389/fncel.2017.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296297PMC
February 2017

Gel-spinning of mimetic collagen and collagen/nano-carbon fibers: Understanding multi-scale influences on molecular ordering and fibril alignment.

J Mech Behav Biomed Mater 2017 01 30;65:552-564. Epub 2016 Aug 30.

Northeastern University, Department of Mechanical and Industrial Engineering, 360 Huntington Avenue, Boston, MA 02115-5000, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmbbm.2016.08.022DOI Listing
January 2017

Peripheral surgical wounding may induce cognitive impairment through interlukin-6-dependent mechanisms in aged mice.

Med Gas Res 2016 Oct-Dec;6(4):180-186. Epub 2016 Dec 30.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.

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http://dx.doi.org/10.4103/2045-9912.196899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223308PMC
December 2016

Hepatitis B patients exhibiting mild alanine aminotransferase elevation: A comparative analysis of treatment with and without Bicyclol tablets.

Biomed Rep 2016 Nov 29;5(5):595-600. Epub 2016 Sep 29.

Center of Computer Management, Navy General Hospital of PLA, Beijing 100048, P.R. China.

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http://dx.doi.org/10.3892/br.2016.765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103681PMC
November 2016

Direct Tracking of Amyloid and Tu Dynamics in Neuroblastoma Cells Using Nanoplasmonic Fiber Tip Probes.

Nano Lett 2016 07 14;16(7):3989-94. Epub 2016 Jun 14.

Rowland Institute at Harvard University , Cambridge, Massachusetts 02142, United States.

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http://dx.doi.org/10.1021/acs.nanolett.6b00320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145310PMC
July 2016

Battery of behavioral tests in mice to study postoperative delirium.

Sci Rep 2016 07 20;6:29874. Epub 2016 Jul 20.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129-2060, USA.

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http://dx.doi.org/10.1038/srep29874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951688PMC
July 2016

Anesthetic sevoflurane reduces levels of hippocalcin and postsynaptic density protein 95.

Mol Neurobiol 2015 29;51(3):853-63. Epub 2014 May 29.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 149 13th St., Room 4310, Charlestown, MA, 02129-2060, USA.

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http://dx.doi.org/10.1007/s12035-014-8746-1DOI Listing
March 2016

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.

Authors:
Tuomas O Kilpeläinen Jayne F Martin Carli Alicja A Skowronski Qi Sun Jennifer Kriebel Mary F Feitosa Åsa K Hedman Alexander W Drong James E Hayes Jinghua Zhao Tune H Pers Ursula Schick Niels Grarup Zoltán Kutalik Stella Trompet Massimo Mangino Kati Kristiansson Marian Beekman Leo-Pekka Lyytikäinen Joel Eriksson Peter Henneman Jari Lahti Toshiko Tanaka Jian'an Luan Fabiola Del Greco M Dorota Pasko Frida Renström Sara M Willems Anubha Mahajan Lynda M Rose Xiuqing Guo Yongmei Liu Marcus E Kleber Louis Pérusse Tom Gaunt Tarunveer S Ahluwalia Yun Ju Sung Yolande F Ramos Najaf Amin Antoinette Amuzu Inês Barroso Claire Bellis John Blangero Brendan M Buckley Stefan Böhringer Yii-Der I Chen Anton J N de Craen David R Crosslin Caroline E Dale Zari Dastani Felix R Day Joris Deelen Graciela E Delgado Ayse Demirkan Francis M Finucane Ian Ford Melissa E Garcia Christian Gieger Stefan Gustafsson Göran Hallmans Susan E Hankinson Aki S Havulinna Christian Herder Dena Hernandez Andrew A Hicks David J Hunter Thomas Illig Erik Ingelsson Andreea Ioan-Facsinay John-Olov Jansson Nancy S Jenny Marit E Jørgensen Torben Jørgensen Magnus Karlsson Wolfgang Koenig Peter Kraft Joanneke Kwekkeboom Tiina Laatikainen Karl-Heinz Ladwig Charles A LeDuc Gordon Lowe Yingchang Lu Pedro Marques-Vidal Christa Meisinger Cristina Menni Andrew P Morris Richard H Myers Satu Männistö Mike A Nalls Lavinia Paternoster Annette Peters Aruna D Pradhan Tuomo Rankinen Laura J Rasmussen-Torvik Wolfgang Rathmann Treva K Rice J Brent Richards Paul M Ridker Naveed Sattar David B Savage Stefan Söderberg Nicholas J Timpson Liesbeth Vandenput Diana van Heemst Hae-Won Uh Marie-Claude Vohl Mark Walker Heinz-Erich Wichmann Elisabeth Widén Andrew R Wood Jie Yao Tanja Zeller Yiying Zhang Ingrid Meulenbelt Margreet Kloppenburg Arne Astrup Thorkild I A Sørensen Mark A Sarzynski D C Rao Pekka Jousilahti Erkki Vartiainen Albert Hofman Fernando Rivadeneira André G Uitterlinden Eero Kajantie Clive Osmond Aarno Palotie Johan G Eriksson Markku Heliövaara Paul B Knekt Seppo Koskinen Antti Jula Markus Perola Risto K Huupponen Jorma S Viikari Mika Kähönen Terho Lehtimäki Olli T Raitakari Dan Mellström Mattias Lorentzon Juan P Casas Stefanie Bandinelli Winfried März Aaron Isaacs Ko W van Dijk Cornelia M van Duijn Tamara B Harris Claude Bouchard Matthew A Allison Daniel I Chasman Claes Ohlsson Lars Lind Robert A Scott Claudia Langenberg Nicholas J Wareham Luigi Ferrucci Timothy M Frayling Peter P Pramstaller Ingrid B Borecki Dawn M Waterworth Sven Bergmann Gérard Waeber Peter Vollenweider Henrik Vestergaard Torben Hansen Oluf Pedersen Frank B Hu P Eline Slagboom Harald Grallert Tim D Spector J W Jukema Robert J Klein Erik E Schadt Paul W Franks Cecilia M Lindgren Rudolph L Leibel Ruth J F Loos

Nat Commun 2016 Feb 1;7:10494. Epub 2016 Feb 1.

MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1038/ncomms10494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740377PMC
February 2016

The application of fluorescence in situ hybridization in different ploidy levels cross-breeding of lily.

PLoS One 2015 26;10(5):e0126899. Epub 2015 May 26.

College of Landscape Architecture, Beijing Forestry University, Beijing, 100083, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126899PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444012PMC
January 2016

Vitamin C Attenuates Isoflurane-Induced Caspase-3 Activation and Cognitive Impairment.

Mol Neurobiol 2015 Dec 4;52(3):1580-1589. Epub 2014 Nov 4.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 149 13th St., Room 4310, Charlestown, MA, 02129-2060, USA.

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http://dx.doi.org/10.1007/s12035-014-8959-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418956PMC
December 2015

Neurodegeneration: etiologies and new therapies.

Biomed Res Int 2015 3;2015:272630. Epub 2015 Feb 3.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1155/2015/272630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320920PMC
November 2015

Surgery plus anesthesia induces loss of attention in mice.

Front Cell Neurosci 2015 8;9:346. Epub 2015 Sep 8.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School Charlestown, MA, USA.

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http://dx.doi.org/10.3389/fncel.2015.00346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561675PMC
October 2015

Direct reprogramming of induced neural progenitors: a new promising strategy for AD treatment.

Transl Neurodegener 2015 18;4. Epub 2015 Apr 18.

Tenth People's Hospital affiliated to Tongji University School of Medicine, Shanghai, 200072 China.

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http://dx.doi.org/10.1186/s40035-015-0028-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422611PMC
May 2015

Chronic treatment with anesthetic propofol improves cognitive function and attenuates caspase activation in both aged and Alzheimer's disease transgenic mice.

J Alzheimers Dis 2014 ;41(2):499-513

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.

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http://dx.doi.org/10.3233/JAD-132792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071129PMC
February 2015

2-deoxy-D-glucose enhances anesthetic effects in mice.

Anesth Analg 2015 Feb;120(2):312-9

From the *Department of Anesthesia, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China; †Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts; and ‡Anesthesia and Operation Center, Chinese PLA General Hospital, Beijing, China.

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http://pdfs.journals.lww.com/anesthesia-analgesia/2016/04000
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http://dx.doi.org/10.1213/ANE.0000000000000520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301982PMC
February 2015

Peripheral surgical wounding and age-dependent neuroinflammation in mice.

PLoS One 2014 5;9(5):e96752. Epub 2014 May 5.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096752PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010504PMC
January 2015

Lab-on-a-Tip (LOT): Where Nanotechnology Can Revolutionize Fibre Optics.

Nanobiomedicine (Rij) 2015 Jan-Dec;2. Epub 2015 Jan 1.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.

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http://dx.doi.org/10.5772/60518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997371PMC
January 2015

Glucose may attenuate isoflurane-induced caspase-3 activation in H4 human neuroglioma cells.

Anesth Analg 2014 Dec;119(6):1373-80

From the *Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts; and †Department of Anesthesia, Beijing Tongren Hospital, Capital Medical University, Beijing, P.R. China.

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http://dx.doi.org/10.1213/ANE.0000000000000383DOI Listing
December 2014

Sevoflurane induces tau phosphorylation and glycogen synthase kinase 3β activation in young mice.

Anesthesiology 2014 Sep;121(3):510-27

From the Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, and Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China (G.T.); Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, and Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R China (J.Z.); Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, and Department of Anesthesiology, East Hospital, Tongji University School of Medicine, Shanghai, P. R. China (L.Z.); Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts (Y.D., Y.Z., Z.X.); Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China (B.Y.); and Department of Anesthesia, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts (G.C., D.J.C.).

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http://dx.doi.org/10.1097/ALN.0000000000000278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165789PMC
September 2014

Inflammatory pain may induce cognitive impairment through an interlukin-6-dependent and postsynaptic density-95-associated mechanism.

Anesth Analg 2014 Aug;119(2):471-80

From the Department of Anaesthesia, Critical Care and Pain Medicine, Geriatric Anaesthesia Research Unit, Massachusetts General Hospital of Harvard Medical School, Charlestown, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000000279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107025PMC
August 2014

Nanotube dispersion and polymer conformational confinement in a nanocomposite fiber: a joint computational experimental study.

J Phys Chem B 2014 Aug 23;118(31):9476-85. Epub 2014 Jul 23.

Department of Mechanical and Industrial Engineering and ‡Department of Civil and Environmental Engineering, Northeastern University , Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/jp504726wDOI Listing
August 2014

Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease.

Neurobiol Dis 2014 May 14;65:188-92. Epub 2014 Jan 14.

The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians & Surgeons, New York, NY, USA; Department of Neurology, Columbia University, College of Physicians & Surgeons, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2013.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235335PMC
May 2014

Preoperative cerebrospinal fluid β-Amyloid/Tau ratio and postoperative delirium.

Ann Clin Transl Neurol 2014 May;1(5):319-328

Divisions of General Medicine and Primary Care and Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215.

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http://dx.doi.org/10.1002/acn3.58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029597PMC
May 2014

Chronic treatment with anesthetic propofol attenuates β-amyloid protein levels in brain tissues of aged mice.

Transl Neurodegener 2014 Apr 11;3(1). Epub 2014 Apr 11.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 149 13th St., Room 4310, Charlestown, MA 02129-2060, USA.

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http://dx.doi.org/10.1186/2047-9158-3-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989795PMC
April 2014

Time-Dependent Effects of Anesthetic Isoflurane on Reactive Oxygen Species Levels in HEK-293 Cells.

Brain Sci 2014 Apr 22;4(2):311-20. Epub 2014 Apr 22.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 149 13th St., 4310H, Charlestown, MA 02129, USA.

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http://www.mdpi.com/2076-3425/4/2/311
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http://dx.doi.org/10.3390/brainsci4020311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101479PMC
April 2014

Fat cell size and adipokine expression in relation to gender, depot, and metabolic risk factors in morbidly obese adolescents.

Obesity (Silver Spring) 2014 Mar 2;22(3):691-7. Epub 2013 Dec 2.

Division of Molecular Genetics, Department of Pediatrics, Columbia University, College of Physicians and Surgeons, New York, USA; Naomi Berrie Diabetes Center, Columbia University, College of Physicians and Surgeons, New York, USA.

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http://dx.doi.org/10.1002/oby.20528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823663PMC
March 2014

The potential dual effects of sevoflurane on AKT/GSK3β signaling pathway.

Med Gas Res 2014 Mar 3;4(1). Epub 2014 Mar 3.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 149 13th St,, Room 4310, Charlestown, MA 02129-2060, USA.

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http://dx.doi.org/10.1186/2045-9912-4-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996018PMC
March 2014

Different effects of anesthetic isoflurane on caspase-3 activation and cytosol cytochrome c levels between mice neural progenitor cells and neurons.

Front Cell Neurosci 2014 30;8:14. Epub 2014 Jan 30.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School Charlestown, MA, USA.

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http://dx.doi.org/10.3389/fncel.2014.00014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906516PMC
February 2014

Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice.

Sci Rep 2014 Jan 20;4:3766. Epub 2014 Jan 20.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129-2060.

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http://dx.doi.org/10.1038/srep03766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895908PMC
January 2014

Surgical incision-induced nociception causes cognitive impairment and reduction in synaptic NMDA receptor 2B in mice.

J Neurosci 2013 Nov;33(45):17737-48

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, 02129-2060, Department of Anesthesia, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, P.R. China, Department of Anesthesia, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, P.R. China, and Massachusetts General Hospital Center for Translational Pain Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129-2060.

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http://dx.doi.org/10.1523/JNEUROSCI.2049-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818549PMC
November 2013

Cerebrospinal fluid aβ to tau ratio and postoperative cognitive change.

Ann Surg 2013 Aug;258(2):364-9

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1097/SLA.0b013e318298b077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880113PMC
August 2013

Structural Polymer-Based Carbon Nanotube Composite Fibers: Understanding the Processing-Structure-Performance Relationship.

Materials (Basel) 2013 Jun 20;6(6):2543-2577. Epub 2013 Jun 20.

Department of Mechanical and Industrial Engineering, Northeastern University, 334 Snell Engineering Center, 360 Huntington Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.3390/ma6062543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458960PMC
June 2013

Sevoflurane anesthesia in pregnant mice induces neurotoxicity in fetal and offspring mice.

Anesthesiology 2013 Mar;118(3):516-26

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA.

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http://pdfs.journals.lww.com/obstetricanesthesia/2014/06000/
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http://anesthesiology.pubs.asahq.org/Article.aspx?doi=10.109
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http://dx.doi.org/10.1097/ALN.0b013e3182834d5dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580035PMC
March 2013

Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment.

Anesthesiology 2013 Mar;118(3):502-15

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129-2060, USA.

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http://dx.doi.org/10.1097/ALN.0b013e3182834d77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580002PMC
March 2013

Tailoring polyacrylonitrile interfacial morphological structure by crystallization in the presence of single-wall carbon nanotubes.

ACS Appl Mater Interfaces 2013 Feb 22;5(3):807-14. Epub 2013 Jan 22.

Northeastern University, Department of Mechanical and Industrial Engineering, College of Engineering, 360 Huntington Avenue, 334 Snell Engineering Center, Boston, Massachusetts 02115-5000, United States.

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http://dx.doi.org/10.1021/am302382mDOI Listing
February 2013

Sleep disturbance induces neuroinflammation and impairment of learning and memory.

Neurobiol Dis 2012 Dec 7;48(3):348-55. Epub 2012 Jul 7.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129-2060, USA.

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http://dx.doi.org/10.1016/j.nbd.2012.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461115PMC
December 2012

TNF-α up-regulates protein level and cell surface expression of the leptin receptor by stimulating its export via a PKC-dependent mechanism.

Endocrinology 2012 Dec 15;153(12):5821-33. Epub 2012 Oct 15.

Division of Molecular Genetics, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.1210/en.2012-1510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512064PMC
December 2012

Anesthetic isoflurane increases phosphorylated tau levels mediated by caspase activation and Aβ generation.

PLoS One 2012 20;7(6):e39386. Epub 2012 Jun 20.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039386PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379981PMC
November 2012

Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ.

Cell 2012 Aug;150(3):620-32

Naomi Berrie Diabetes Center, Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00928674120078
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http://dx.doi.org/10.1016/j.cell.2012.06.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413172PMC
August 2012

Propofol and magnesium attenuate isoflurane-induced caspase-3 activation via inhibiting mitochondrial permeability transition pore.

Med Gas Res 2012 Aug 17;2(1):20. Epub 2012 Aug 17.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 149 13th St, Room 4310, Charlestown, MA, 02129-2060, USA.

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http://dx.doi.org/10.1186/2045-9912-2-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489514PMC
August 2012

The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-α, IL-6, and IL-1β.

Neurobiol Aging 2012 Jul 28;33(7):1364-78. Epub 2010 Dec 28.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129-2060, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2010.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117127PMC
July 2012

Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory.

Ann Neurol 2012 May 24;71(5):687-98. Epub 2012 Feb 24.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, USA.

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http://dx.doi.org/10.1002/ana.23536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942786PMC
May 2012

Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aβ oligomerization.

PLoS One 2011 1;6(11):e27019. Epub 2011 Nov 1.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0027019PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206055PMC
March 2012

2-Deoxy-D-glucose attenuates isoflurane-induced cytotoxicity in an in vitro cell culture model of H4 human neuroglioma cells.

Anesth Analg 2011 Dec 29;113(6):1468-75. Epub 2011 Sep 29.

Geriatric Anesthesia Research Unit, Massachusetts General Hospital and Harvard Medical School, 149 13th St., Room 4310, Charlestown, MA 02129-2060, USA.

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http://dx.doi.org/10.1213/ANE.0b013e31822e913cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224184PMC
December 2011

The potential dual effects of anesthetic isoflurane on Aβ-induced apoptosis.

Curr Alzheimer Res 2011 Nov;8(7):741-52

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129-2060, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973025PMC
http://dx.doi.org/10.2174/156720511797633223DOI Listing
November 2011

The potential dual effects of anesthetic isoflurane on hypoxia-induced caspase-3 activation and increases in β-site amyloid precursor protein-cleaving enzyme levels.

Anesth Analg 2011 Jul 25;113(1):145-52. Epub 2011 Apr 25.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 149 13th St., Room 4310, Charlestown, MA 02129-2060, USA.

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http://dx.doi.org/10.1213/ANE.0b013e3182185feeDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123429PMC
July 2011

RNA interference-mediated silencing of BACE and APP attenuates the isoflurane-induced caspase activation.

Med Gas Res 2011 Apr 28;1(1). Epub 2011 Apr 28.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129-2060; USA.

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http://dx.doi.org/10.1186/2045-9912-1-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191487PMC
April 2011

Chronic leucine supplementation improves glycemic control in etiologically distinct mouse models of obesity and diabetes mellitus.

Nutr Metab (Lond) 2010 Jul 12;7:57. Epub 2010 Jul 12.

Department of Pediatrics, Division of Molecular Genetics, Columbia University, New York, USA.

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http://dx.doi.org/10.1186/1743-7075-7-57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914079PMC
July 2010

Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice.

Anesthesiology 2010 Jun;112(6):1404-16

Geriatric Anesthesia Research Unit, Departmentof Anesthesia, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129-2060, USA.

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http://anesthesiology.pubs.asahq.org/Article.aspx?doi=10.109
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http://dx.doi.org/10.1097/ALN.0b013e3181d94de1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877754PMC
June 2010

Utility of transplantation in studying adipocyte biogenesis and function.

Authors:
Yiying Zhang

Mol Cell Endocrinol 2010 Apr 4;318(1-2):15-23. Epub 2009 Sep 4.

Division of Molecular Genetics, Department of Pediatrics, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.mce.2009.08.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826534PMC
April 2010

The mitochondrial pathway of anesthetic isoflurane-induced apoptosis.

J Biol Chem 2010 Feb 10;285(6):4025-37. Epub 2009 Dec 10.

Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129-2060, USA.

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http://dx.doi.org/10.1074/jbc.M109.065664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823544PMC
February 2010

Paradoxical coupling of triglyceride synthesis and fatty acid oxidation in skeletal muscle overexpressing DGAT1.

Diabetes 2009 Nov 12;58(11):2516-24. Epub 2009 Aug 12.

Department of Medicine, Preventive Medicine and Nutrition, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.2337/db08-1096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768165PMC
November 2009

Nitrous oxide plus isoflurane induces apoptosis and increases beta-amyloid protein levels.

Anesthesiology 2009 Oct;111(4):741-52

Department of Anesthesia, Critical Care and Pain Medicine, Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital and Harvard Medical School, 114 16th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1097/ALN.0b013e3181b27fd4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797570PMC
October 2009

Preadipocyte transplantation: an in vivo study of direct leptin signaling on adipocyte morphogenesis and cell size.

Am J Physiol Regul Integr Comp Physiol 2009 May 4;296(5):R1339-47. Epub 2009 Feb 4.

Division of Molecular Genetics, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1152/ajpregu.90691.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689822PMC
May 2009

Specificity rule discovery in HIV-1 protease cleavage site analysis.

Comput Biol Chem 2008 Feb 29;32(1):71-8. Epub 2007 Sep 29.

Department of Computer Science Education, Korea University, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.compbiolchem.2007.09.006DOI Listing
February 2008

Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalities.

Endocrinology 2007 Aug 10;148(8):3987-97. Epub 2007 May 10.

Division of Molecular Genetics, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1210/en.2007-0261DOI Listing
August 2007

Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms.

Diabetes 2007 Jun 14;56(6):1647-54. Epub 2007 Mar 14.

Department of Pediatrics, Division of Molecular Genetics, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.2337/db07-0123DOI Listing
June 2007

Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance.

J Clin Invest 2007 Jun 17;117(6):1679-89. Epub 2007 May 17.

Department of Medicine, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1172/JCI30565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866250PMC
June 2007

Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes.

J Clin Invest 2005 Dec 10;115(12):3484-93. Epub 2005 Nov 10.

Department of Medicine, Division of Preventative Medicine, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1172/JCI24059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280964PMC
December 2005

Whole-body insulin resistance in the absence of obesity in FVB mice with overexpression of Dgat1 in adipose tissue.

Diabetes 2005 Dec;54(12):3379-86

Department of Medicine, Columbia University College of Physicians and Surgeons, 630 West 168th St., PH 10-305J, New York, New York 10032, USA.

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http://dx.doi.org/10.2337/diabetes.54.12.3379DOI Listing
December 2005

Effects of obesity on the relationship of leptin mRNA expression and adipocyte size in anatomically distinct fat depots in mice.

Am J Physiol Regul Integr Comp Physiol 2004 Jul 4;287(1):R112-9. Epub 2004 Mar 4.

Division of Molecular Genetics, Columbia Univ., College of Physicians and Surgeons, Russ Berrie Pavilion, 1150 St. Nicholas Ave., New York, NY 10032, USA.

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http://dx.doi.org/10.1152/ajpregu.00028.2004DOI Listing
July 2004

Posttranscriptional control of the expression and function of diacylglycerol acyltransferase-1 in mouse adipocytes.

J Biol Chem 2002 Dec 28;277(52):50876-84. Epub 2002 Oct 28.

Department of Medicine, Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1074/jbc.M207353200DOI Listing
December 2002

Determinants of leptin gene expression in fat depots of lean mice.

Am J Physiol Regul Integr Comp Physiol 2002 Jan;282(1):R226-34

Division of Molecular Genetics, Department of Pediatrics, and the Naomi Berrie Diabetes Center, Columbia University College of Physicians and Surgeons, New York 10032, USA.

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http://dx.doi.org/10.1152/ajpregu.00392.2001DOI Listing
January 2002