Publications by authors named "Yixin Zeng"

53Publications

A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo.

Signal Transduct Target Ther 2020 Aug 19;5(1):152. Epub 2020 Aug 19.

State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.

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August 2020

Analysis of 47 Non-MHC Ankylosing Spondylitis Susceptibility Loci Regarding Associated Variants across Whites and Han Chinese.

J Rheumatol 2020 05 15;47(5):674-681. Epub 2019 Sep 15.

From the Department of Rheumatology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore; The Jackson Laboratory, Farmington, Connecticut, USA; the Singapore Eye Research Institute (SERI); the Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), the Health Systems and Services Research, Duke-National University of Singapore (NUS) Medical School; Departments of Ophthalmology and Pediatrics, Yong Loo Lin School of Medicine; the Khoo Teck Puat-National University Children's Medical Institute; the Saw Swee Hock School of Public Health, National University of Singapore, Singapore; the division of Cancer Control and Population Sciences, University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou; Shandong Provincial Institute of Dermatology and Venereology and Hospital for Skin Diseases, Shandong First Medical University and Shandong Academy of Medical Sciences; National Clinical Key Project of Dermatology and Venereology, Jinan, Shandong; Institute of Dermatology and Department of Dermatology, Huashan Hospital of Fudan University, Guangzhou; Institute of Dermatology and Department of Dermatology, No. 1 Hospital, Anhui Medical University; Key Laboratory of Dermatology, Ministry of Education (Anhui Medical University), Hefei; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing, China.

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May 2020

The c-Myc-regulated miR-17-92 cluster mediates ATRA-induced APL cell differentiation.

Asia Pac J Clin Oncol 2019 Dec 1;15(6):364-370. Epub 2019 Jul 1.

Department of Experimental Research, Sun Yat-sen University Cancer Center, State Key Laboratory Oncology in South China, Guangzhou, China.

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December 2019

Changes in Expression of Multiple Checkpoint Molecules and Infiltration of Tumor Immune Cells after Neoadjuvant Chemotherapy in Gastric Cancer.

J Cancer 2019 2;10(12):2754-2763. Epub 2019 Jun 2.

State Key Laboratory of Molecular Oncology, National Cancer Center /National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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June 2019

The novel non-immunological role and underlying mechanisms of B7-H3 in tumorigenesis.

J Cell Physiol 2019 12 21;234(12):21785-21795. Epub 2019 Jun 21.

Department of Radiotherapy of the First Affiliated Hospital, University of South China, Hengyang, China.

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December 2019

Outcome of chemotherapy with or without targeted agents in metastatic colorectal cancer patients with deficient DNA mismatch repair: A single center, cohort study.

Asia Pac J Clin Oncol 2019 Jun 29;15(3):128-135. Epub 2019 Jan 29.

Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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June 2019

Immunization With Fc-Based Recombinant Epstein-Barr Virus gp350 Elicits Potent Neutralizing Humoral Immune Response in a BALB/c Mice Model.

Front Immunol 2018 1;9:932. Epub 2018 May 1.

Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Department of Experimental Research, Sun Yat-Sen University Cancer Center, Guangzhou, China.

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July 2019

Successful treatment with pazopanib plus PD-1 inhibitor and RAK cells for advanced primary hepatic angiosarcoma: a case report.

BMC Cancer 2018 02 21;18(1):212. Epub 2018 Feb 21.

Department of Geriatric, Beijing Hospital, National Center of Gerontology, Beijing, 100730, People's Republic of China.

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February 2018

Nasopharyngeal carcinoma super-enhancer-driven ETV6 correlates with prognosis.

Proc Natl Acad Sci U S A 2017 09 22;114(36):9683-9688. Epub 2017 Aug 22.

Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115;

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September 2017

Estimation of heritability for nine common cancers using data from genome-wide association studies in Chinese population.

Int J Cancer 2017 Jan 11;140(2):329-336. Epub 2016 Oct 11.

Department of Epidemiology and Biostatistics, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China.

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January 2017

Comprehensive profiling of EBV gene expression in nasopharyngeal carcinoma through paired-end transcriptome sequencing.

Front Med 2016 Mar 11;10(1):61-75. Epub 2016 Mar 11.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.

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March 2016

In vitro thermosensitivity of rat lateral parabrachial neurons.

Neurosci Lett 2016 Apr 2;619:15-20. Epub 2016 Mar 2.

Department of Physiology, Chengdu Medical College, Chengdu, Sichuan 610500, PR China; Key Laboratory of Thermoregulation and Inflammation of Sichuan Higher Education Institutes, Chengdu Medical College, Chengdu, Sichuan 610500, PR China. Electronic address:

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April 2016

Common variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populations.

Oncotarget 2016 Jan;7(1):759-70

State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing, China.

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January 2016

TERT Polymorphism rs2736100-C Is Associated with EGFR Mutation-Positive Non-Small Cell Lung Cancer.

Clin Cancer Res 2015 Nov 6;21(22):5173-5180. Epub 2015 Jul 6.

Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, IN, USA.

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November 2015

BIRC6-ALK, a Novel Fusion Gene in ALK Break-Apart FISH-Negative Lung Adenocarcinoma, Responds to Crizotinib.

J Thorac Oncol 2015 Jun;10(6):e37-9

Departments of *Pathology, †Medical Oncology, ‡Diagnostic Imaging, §Laboratory of Cell and Molecular Biology and State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; ‖MyGenostics Inc., Baltimore, MD, USA; ¶Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College; #Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, China; and **State Key Laboratory of Oncology in Southern China, Guangzhou, China.

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June 2015

Tumor growth and metastasis can be inhibited by maintaining genomic stability in cancer cells.

Front Med 2015 Mar 7;9(1):57-62. Epub 2015 Feb 7.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.

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March 2015

Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients.

Blood 2014 Oct 29;124(16):2544-53. Epub 2014 Aug 29.

Clinical Immunology, Department of Laboratory Medicine, Karolinska Institutet at Karolinska University Hospital, Huddinge, Sweden; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, and Collaborative Innovation Center of Cancer Medicine, Guangzhou, China; and Guangzhou Institute of Respiratory Disease and China State Key Laboratory of Respiratory Disease, Guangzhou, China.

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October 2014

Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations.

Authors:
Chen Wu Zhaoming Wang Xin Song Xiao-Shan Feng Christian C Abnet Jie He Nan Hu Xian-Bo Zuo Wen Tan Qimin Zhan Zhibin Hu Zhonghu He Weihua Jia Yifeng Zhou Kai Yu Xiao-Ou Shu Jian-Min Yuan Wei Zheng Xue-Ke Zhao She-Gan Gao Zhi-Qing Yuan Fu-You Zhou Zong-Min Fan Ji-Li Cui Hong-Li Lin Xue-Na Han Bei Li Xi Chen Sanford M Dawsey Linda Liao Maxwell P Lee Ti Ding You-Lin Qiao Zhihua Liu Yu Liu Dianke Yu Jiang Chang Lixuan Wei Yu-Tang Gao Woon-Puay Koh Yong-Bing Xiang Ze-Zhong Tang Jin-Hu Fan Jing-Jing Han Sheng-Li Zhou Peng Zhang Dong-Yun Zhang Yuan Yuan Ying Huang Chunling Liu Kan Zhai Yan Qiao Guangfu Jin Chuanhai Guo Jianhua Fu Xiaoping Miao Changdong Lu Haijun Yang Chaoyu Wang William A Wheeler Mitchell Gail Meredith Yeager Jeff Yuenger Er-Tao Guo Ai-Li Li Wei Zhang Xue-Min Li Liang-Dan Sun Bao-Gen Ma Yan Li Sa Tang Xiu-Qing Peng Jing Liu Amy Hutchinson Kevin Jacobs Carol Giffen Laurie Burdette Joseph F Fraumeni Hongbing Shen Yang Ke Yixin Zeng Tangchun Wu Peter Kraft Charles C Chung Margaret A Tucker Zhi-Chao Hou Ya-Li Liu Yan-Long Hu Yu Liu Li Wang Guo Yuan Li-Sha Chen Xiao Liu Teng Ma Hui Meng Li Sun Xin-Min Li Xiu-Min Li Jian-Wei Ku Ying-Fa Zhou Liu-Qin Yang Zhou Wang Yin Li Qirenwang Qige Wen-Jun Yang Guang-Yan Lei Long-Qi Chen En-Min Li Ling Yuan Wen-Bin Yue Ran Wang Lu-Wen Wang Xue-Ping Fan Fang-Heng Zhu Wei-Xing Zhao Yi-Min Mao Mei Zhang Guo-Lan Xing Ji-Lin Li Min Han Jing-Li Ren Bin Liu Shu-Wei Ren Qing-Peng Kong Feng Li Ilyar Sheyhidin Wu Wei Yan-Rui Zhang Chang-Wei Feng Jin Wang Yu-Hua Yang Hong-Zhang Hao Qi-De Bao Bao-Chi Liu Ai-Qun Wu Dong Xie Wan-Cai Yang Liang Wang Xiao-Hang Zhao Shu-Qing Chen Jun-Yan Hong Xue-Jun Zhang Neal D Freedman Alisa M Goldstein Dongxin Lin Philip R Taylor Li-Dong Wang Stephen J Chanock

Nat Genet 2014 Sep 17;46(9):1001-1006. Epub 2014 Aug 17.

Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), National Institutes of Health, Bethesda, Maryland, USA.

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September 2014

Expression of variant isoforms of the tyrosine kinase SYK determines the prognosis of hepatocellular carcinoma.

Cancer Res 2014 Mar 29;74(6):1845-56. Epub 2014 Jan 29.

Authors' Affiliations: State Key Laboratory of Oncology in South China; Department of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center; Department of Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; and Division of Pharmacy, The University of Texas M.D. Anderson Cancer Center, Houston, Texas.

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March 2014

α4 contributes to bladder urothelial carcinoma cell invasion and/or metastasis via regulation of E-cadherin and is a predictor of outcome in bladder urothelial carcinoma patients.

Eur J Cancer 2014 Mar 2;50(4):840-51. Epub 2014 Jan 2.

State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangdong, Guangzhou 510060, China; Department of Pathology, Sun Yat-Sen University Cancer Center, Guangdong, Guangzhou 510060, China. Electronic address:

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March 2014

High expression of H3K27me3 is an independent predictor of worse outcome in patients with urothelial carcinoma of bladder treated with radical cystectomy.

Biomed Res Int 2013 4;2013:390482. Epub 2013 Sep 4.

State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, China ; Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, China.

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June 2014

Scavenger receptor B1 is a potential biomarker of human nasopharyngeal carcinoma and its growth is inhibited by HDL-mimetic nanoparticles.

Theranostics 2013 25;3(7):477-86. Epub 2013 Jun 25.

Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology, Wuhan 430074, China.

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February 2014

Rapid health transition in China, 1990-2010: findings from the Global Burden of Disease Study 2010.

Lancet 2013 Jun;381(9882):1987-2015

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing, China.

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June 2013

Policy dialogue on China's changing burden of disease.

Lancet 2013 Jun;381(9882):1961-2

Harvard School of Public Health, Boston, MA 02115, USA.

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June 2013

[Bacterial diversity within different sections of summer sea-ice samples from the Prydz Bay, Antarctica].

Wei Sheng Wu Xue Bao 2013 Feb;53(2):185-96

SOA Key Laboratory for Polar Science, Polar Research Institute of China, Shanghai 200136, China.

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February 2013

The case-only test for gene-environment interaction is not uniformly powerful: an empirical example.

Genet Epidemiol 2013 May 13;37(4):402-7. Epub 2013 Mar 13.

Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, MA, USA.

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May 2013

Risk prediction of esophageal squamous-cell carcinoma with common genetic variants and lifestyle factors in Chinese population.

Carcinogenesis 2013 Aug 27;34(8):1782-6. Epub 2013 Mar 27.

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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August 2013

Targeted and personalized therapy for cancer: theory and practice in China.

Sci China Life Sci 2011 Dec 7;54(12):1081-4. Epub 2012 Jan 7.

State Key Laboratory of Oncology in South China, Guangzhou 510060, China.

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December 2011

Static pressure accelerates ox-LDL-induced cholesterol accumulation via SREBP-1-mediated caveolin-1 downregulation in cultured vascular smooth muscle cells.

Biochem Biophys Res Commun 2010 Dec 29;403(1):52-8. Epub 2010 Oct 29.

Department of Pharmacology, School of Pharmaceutics, Central South University, Changsha 410083, Hunan, China.

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December 2010

14-3-3 mediates apelin-13-induced enhancement of adhesion of monocytes to human umbilical vein endothelial cells.

Acta Biochim Biophys Sin (Shanghai) 2010 Jun;42(6):403-9

Institute of Pharmacy and Pharmacology, University of South China, Hengyang, China.

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June 2010

Synergism of BARF1 with Ras induces malignant transformation in primary primate epithelial cells and human nasopharyngeal epithelial cells.

Neoplasia 2009 Sep;11(9):964-73

Department of Thoracic Oncology, Tianjin Lung Cancer Center, Tianjin Cancer Institute & Hospital, Tianjin Medical University, Tianjin 300060, China.

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September 2009

A major EBNA1 variant from Asian EBV isolates shows enhanced transcriptional activity compared to prototype B95.8.

Virus Res 2008 Mar 21;132(1-2):15-24. Epub 2007 Dec 21.

Department of Microbiology, Tumor and Cell Biology , Karolinska Institutet, S-171 77 Stockholm, Sweden.

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March 2008

Minicircle-IFNgamma induces antiproliferative and antitumoral effects in human nasopharyngeal carcinoma.

Clin Cancer Res 2006 Aug;12(15):4702-13

State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-sen University, Guangzhou, PR China.

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August 2006

Oncogenic transformation by SEI-1 is associated with chromosomal instability.

Cancer Res 2005 Aug;65(15):6504-8

Department of Clinical Oncology, The University of Hong Kong Medical Center, Hong Kong SAR, China.

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August 2005

A rare polymorphism of the COX7B2 gene in a Cantonese family with nasopharyngeal carcinoma.

Sci China C Life Sci 2004 Oct;47(5):449-53

Cancer Center, Sun Yat-sen University, Guangzhou 510060, China.

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October 2004

[Differentially expressed gene in nasopharyngeal carcinoma cell lines with various metastatic potentialities].

Zhonghua Zhong Liu Za Zhi 2002 Sep;24(5):430-4

Cancer Center, Sun Yat-sen University, Guangzhou 510060, China.

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September 2002

Rapid tissue microarray assay of p16 protein expression for different stage nasopharyngeal carcinoma.

Zhonghua Bing Li Xue Za Zhi 2002 Apr;31(2):132-4

Department of Etiology, Cancer Institute, Cancer Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060. China (Email:

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April 2002