Yiping Fan

Yiping Fan

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Yiping Fan

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ChIPseqSpikeInFree: A ChIP-seq normalization approach to reveal global changes in histone modifications without spike-in.

Bioinformatics 2019 Sep 30. Epub 2019 Sep 30.

Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1093/bioinformatics/btz720DOI Listing
September 2019

Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across populations.

Genome Res 2019 08 27;29(8):1262-1276. Epub 2019 Jun 27.

Division of Developmental Biology, Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1101/gr.246884.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673717PMC
August 2019

Adipocyte-specific disruption of ATPase copper transporting α in mice accelerates lipoatrophy.

Diabetologia 2019 Aug 8. Epub 2019 Aug 8.

State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China, 100193.

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http://dx.doi.org/10.1007/s00125-019-4966-2DOI Listing
August 2019

Transcriptional Response of Subcutaneous White Adipose Tissue to Acute Cold Exposure in Mice.

Int J Mol Sci 2019 Aug 15;20(16). Epub 2019 Aug 15.

State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, 100193 Beijing, China.

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http://dx.doi.org/10.3390/ijms20163968DOI Listing
August 2019

A Key Role for the Ubiquitin Ligase UBR4 in Myofiber Hypertrophy in Drosophila and Mice.

Cell Rep 2019 Jul;28(5):1268-1281.e6

Division of Developmental Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.06.094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697171PMC
July 2019

Tissue-specific alteration of gene expression and function by RU486 and the GeneSwitch system.

NPJ Aging Mech Dis 2019 21;5. Epub 2019 May 21.

1Division of Developmental Biology, Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105 USA.

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http://dx.doi.org/10.1038/s41514-019-0036-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529481PMC
May 2019

Differentiation of human pluripotent stem cells into neurons or cortical organoids requires transcriptional co-regulation by UTX and 53BP1.

Nat Neurosci 2019 03 4;22(3):362-373. Epub 2019 Feb 4.

Department of Developmental Neurobiology and Division of Developmental Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1038/s41593-018-0328-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511450PMC
March 2019

A novel gas-solids separator scheme of coupling cyclone with circulating granular bed filter (C-CGBF).

J Hazard Mater 2019 Jan 19;362:403-411. Epub 2018 Jul 19.

State Key Laboratory of Heavy Oil Processing, College of Chemical Engineering, China University of Petroleum, Beijing, 102249, China. Electronic address:

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http://dx.doi.org/10.1016/j.jhazmat.2018.07.065DOI Listing
January 2019

The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number.

Dev Cell 2018 12 25;47(5):576-591.e8. Epub 2018 Oct 25.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2018.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296252PMC
December 2018

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.

Cancer Cell 2018 09 23;34(3):411-426.e19. Epub 2018 Aug 23.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, MS 323, Memphis, TN 38105-3678, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158019PMC
September 2018

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.

Cell 2017 Jun 22;170(1):142-157.e19. Epub 2017 Jun 22.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568784PMC
June 2017

Zika Virus Infects Human Fetal Brain Microglia and Induces Inflammation.

Clin Infect Dis 2017 Apr;64(7):914-920

Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR).

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https://academic.oup.com/cid/article/3041121/Zika
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http://dx.doi.org/10.1093/cid/ciw878DOI Listing
April 2017

Binding of estrogen receptors to switch sites and regulatory elements in the immunoglobulin heavy chain locus of activated B cells suggests a direct influence of estrogen on antibody expression.

Mol Immunol 2016 09 3;77:97-102. Epub 2016 Aug 3.

Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2016.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010968PMC
September 2016

c-Fos Repression by Piwi Regulates Drosophila Ovarian Germline Formation and Tissue Morphogenesis.

PLoS Genet 2016 09 13;12(9):e1006281. Epub 2016 Sep 13.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021354PMC
September 2016

Msh2 deficiency leads to dysmyelination of the corpus callosum, impaired locomotion, and altered sensory function in mice.

Sci Rep 2016 08 1;6:30757. Epub 2016 Aug 1.

Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, 38105, USA.

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http://dx.doi.org/10.1038/srep30757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967871PMC
August 2016

Evaluation of artemisinins for the treatment of acute myeloid leukemia.

Cancer Chemother Pharmacol 2016 06 28;77(6):1231-43. Epub 2016 Apr 28.

Division of Pharmaceutics, College of Pharmacy, The Ohio State University, 500 W. 12th St., Columbus, OH, 43210, USA.

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http://dx.doi.org/10.1007/s00280-016-3038-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918815PMC
June 2016

The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling.

Genes Dev 2015 Dec 19;29(23):2475-89. Epub 2015 Nov 19.

Department of Developmental Neurobiology, Division of Developmental Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA;

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http://dx.doi.org/10.1101/gad.267419.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691951PMC
December 2015

The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles.

Drug Metab Dispos 2015 Aug 28;43(8):1226-35. Epub 2015 May 28.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee (A.S.C., E.G.S.); Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington (B.P., Y.S., A.F., K.E.T.); Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee (D.F., Y.F., S.W., G.W.); Department of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska Institutet, Stockholm, Sweden (E.A.); and Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (S.C.S.)

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http://dmd.aspetjournals.org/cgi/doi/10.1124/dmd.115.064428
Publisher Site
http://dx.doi.org/10.1124/dmd.115.064428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518065PMC
August 2015

Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors.

Cell Stem Cell 2015 Jul;17(1):101-15

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547539PMC
July 2015

Regionally-specified second trimester fetal neural stem cells reveals differential neurogenic programming.

PLoS One 2014 2;9(9):e105985. Epub 2014 Sep 2.

Department of Reproductive Medicine, KK Women's and Children's Hospital, Singapore, Singapore; Experimental Fetal Medicine Group, Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University Health System, Singapore, Singapore; Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, Singapore, Singapore.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105985PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152177PMC
May 2015

Survival analysis of infected mice reveals pathogenic variations in the genome of avian H1N1 viruses.

Sci Rep 2014 Dec 12;4:7455. Epub 2014 Dec 12.

Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, 38105, United States.

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http://dx.doi.org/10.1038/srep07455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264002PMC
December 2014

Genetic variation in aldo-keto reductase 1D1 (AKR1D1) affects the expression and activity of multiple cytochrome P450s.

Drug Metab Dispos 2013 Aug 23;41(8):1538-47. Epub 2013 May 23.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1124/dmd.113.051672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162005PMC
August 2013

ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity.

J Biol Chem 2012 Apr 31;287(16):12679-90. Epub 2012 Jan 31.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1074/jbc.M111.336180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339991PMC
April 2012

Unravelling the mystery of stem/progenitor cells in human breast milk.

PLoS One 2010 Dec 28;5(12):e14421. Epub 2010 Dec 28.

Experimental Fetal Medicine Group, Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University Health System, Singapore, Singapore.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014421PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010984PMC
December 2010

Identification of nestin-positive putative mammary stem cells in human breastmilk.

Cell Tissue Res 2007 Jul 18;329(1):129-36. Epub 2007 Apr 18.

School of Biomedical, Biomolecular and Chemical Sciences, Faculty of Life and Physical Sciences, M310, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.

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http://dx.doi.org/10.1007/s00441-007-0390-xDOI Listing
July 2007

A high-resolution map of Arabidopsis recombinant inbred lines by whole-genome exon array hybridization.

PLoS Genet 2006 Sep 27;2(9):e144. Epub 2006 Jul 27.

Torrey Mesa Research Institute, Syngenta Research and Technology, San Diego, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.0020144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564425PMC
September 2006

Large-scale sequence analysis of avian influenza isolates.

Science 2006 Mar 26;311(5767):1576-80. Epub 2006 Jan 26.

Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1126/science.1121586DOI Listing
March 2006