Publications by authors named "Yinyin Yan"

2 Publications

  • Page 1 of 1

One-Step Preparation of Robust Superhydrophobic Foam for Oil/Water Separation by Pulse Electrodeposition.

Langmuir 2021 Jun 3;37(23):7043-7054. Epub 2021 Jun 3.

College of Mechanical and Electrical Engineering, Central South University, Changsha 410083, China.

Frequent leakage and pollution of oily wastewater seriously affect the world's ecosystem safety and economic development, which prompts us to urgently develop a highly effective, low-cost, wear-resistant, chemically stable, and environmentally friendly new functional material for oil/water separation. In this paper, a robust superhydrophobic material was successfully electrodeposited on the porous copper foam substrates in myristic acid (CH(CH)COOH) and lanthanum chloride (LaCl·6HO) electrodeposition solution under a continuous pumping circulation and rotation condition. Moreover, SEM, EDS, XRD, FTIR, and XPS technologies were utilized to characterize the surface morphology and chemical composition information. The superhydrophobic property was evaluated by optical contact angle instrument and high-speed camera. It turned out that the micro/nanostructures were mainly composed of lanthanum myristate, and static CA of superhydrophobic copper foam (SCF) was up to 165.2° with SA ≈ 2°. Besides, the SCF exhibited a better performance with good anticorrosion, excellent chemical stability, and outstanding mechanical stability. Furthermore, the SCF can achieve up to 98.6% oil/water separation efficiency. More importantly, by employing this novel processing method, it can effectively save time and provide a promising potential way to make denser and thicker foams for continuous oil/water separation and may be easily applied to other conductive metal matrix materials.
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June 2021

antitumor effects of carboxymethyl chitosan-conjugated triptolide after oral administration.

Drug Deliv 2020 Dec;27(1):848-854

Academy of Chinese Medicine Sciences, Henan University of Chinese Medicine, Zhengzhou, China.

The purpose of this study is to evaluate antitumor efficacy and subacute toxicity of triptolide (TP) prodrug, a conjugate between TP and carboxymethyl chitosan (CC). The CCTP conjugate contained 4∼ wt % TP and displayed excellent aqueous solubility (5 mg/mL) as compared to the native TP (17 μg/mL). cytotoxicity of CCTP conjugate was evaluated by CCK8 assay against human pancreatic cancer (PC) cell lines, showing comparable the half maximal inhibitory concentration (IC) values to the parent TP. In a mouse model of PC (BxPC-3), the CCTP conjugate administered orally (at dose levels as low as 0.2 mg TP equivalent/kg) showed comparable efficacy in reducing or eliminating xenograft tumor to the same dose of TP, but exhibited much lower subacute toxicity as seen in body weight loss and hematological toxicity.
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December 2020