Publications by authors named "Yinon Ben-Neriah"

55Publications

The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic.

Nature 2020 10 29;586(7827):133-138. Epub 2020 Jul 29.

The Lautenberg Center for Immunology and Cancer Research, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

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October 2020

β-TrCP upregulates HIF-1 in prostate cancer cells.

Prostate 2019 03 28;79(4):403-413. Epub 2018 Nov 28.

Prostate Cancer Research Laboratory, Department of Urology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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March 2019

Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.

EMBO J 2017 10 28;36(20):3046-3061. Epub 2017 Sep 28.

The Lautenberg Center for Immunology, Institute of Medical Research, Hebrew University-Hadassah Medical School, Jerusalem, Israel

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October 2017

CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.

Proc Natl Acad Sci U S A 2017 09 6;114(38):E8035-E8044. Epub 2017 Sep 6.

The Lautenberg Center for Immunology and Cancer Research, Institute for Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel

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September 2017

Cancer Cell-Autonomous Parainflammation Mimics Immune Cell Infiltration.

Cancer Res 2017 07 30;77(14):3740-3744. Epub 2017 Jun 30.

The Lautenberg Center for Immunology and Cancer Research, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

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July 2017

p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression.

Oncotarget 2016 Aug;7(33):52643-52660

Department of Hematology, Hebrew University Faculty of Medicine and Hadassah University Hospital, Jerusalem, Israel.

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August 2016

Widespread parainflammation in human cancer.

Genome Biol 2016 07 8;17(1):145. Epub 2016 Jul 8.

The Lautenberg Center for Immunology and Cancer Research, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, 91120, Israel.

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July 2016

Inflammatory networks underlying colorectal cancer.

Nat Immunol 2016 Mar;17(3):230-40

The Lautenberg Center for Immunology and Cancer Research, Institute for Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

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March 2016

Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.

Mol Cell Biol 2016 Jan 25;36(7):1124-35. Epub 2016 Jan 25.

Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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January 2016

A Systematic Approach to Defining the microRNA Landscape in Metastasis.

Cancer Res 2015 Aug 11;75(15):3010-9. Epub 2015 Jun 11.

Department of Experimental Surgery, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. Centre for Biomedicine and Medical Technology Mannheim, Mannheim, Germany.

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August 2015

Senescence-associated inflammatory responses: aging and cancer perspectives.

Trends Immunol 2015 Apr 21;36(4):217-28. Epub 2015 Mar 21.

The Lautenberg Center for Immunology and Cancer Research, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel. Electronic address:

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April 2015

Animal model studies indicate a candidate biomarker for sorafenib treatment of hepatocellular carcinoma.

Mol Cell Oncol 2015 Jan-Mar;2(1):e968028. Epub 2014 Oct 30.

The Lautenberg Center for Immunology; IMRIC, Hebrew University - Hadassah Medical School; Jerusalem, Israel; Department of Pathology; Hadassah-Hebrew University Medical Center; Jerusalem, Israel.

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June 2016

Acquisition of an immunosuppressive protumorigenic macrophage phenotype depending on c-Jun phosphorylation.

Proc Natl Acad Sci U S A 2014 Dec 24;111(49):17582-7. Epub 2014 Nov 24.

Department of Immunology and Cancer Research, Institute for Medical Research Israel Canada (IMRIC), Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel; Department of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel;

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December 2014

Prox1 promotes expansion of the colorectal cancer stem cell population to fuel tumor growth and ischemia resistance.

Cell Rep 2014 Sep 18;8(6):1943-1956. Epub 2014 Sep 18.

Translational Cancer Biology Program, University of Helsinki, Biomedicum Helsinki, 00014 Helsinki, Finland; Wihuri Research Institute, Biomedicum Helsinki, 00014 Helsinki, Finland. Electronic address:

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September 2014

Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β.

Proc Natl Acad Sci U S A 2014 May 13;111(21):E2229-36. Epub 2014 May 13.

Translational Cancer Biology Program andWihuri Research Institute, Biomedicum Helsinki, University of Helsinki, FI-00014, Helsinki, Finland;

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May 2014

Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment.

Cancer Discov 2014 Jun 31;4(6):730-43. Epub 2014 Mar 31.

Authors' Affiliations:The Lautenberg Center for Immunology; Department of Developmental Biology and Cancer Research, IMRIC, Hadassah Medical School, Hebrew University;Department of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem; Liver Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Institute of Pathology, University Hospital Basel, Basel, Switzerland; Division of Signal Transduction and Growth Control (A100), Division of Molecular Genetics (B060), and Junior Group Molecular Mechanisms of Head and Neck Tumors (A102), German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance; Institute of Pathology, University Hospital Heidelberg; Departments of Otolaryngology, Head and Neck Surgery and Internal Medicine, University Hospital Heidelberg, Heidelberg; and Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, GermanyAuthors' Affiliations:The Lautenberg Center for Immunology; Department of Developmental Biology and Cancer Research, IMRIC, Hadassah Medical School, Hebrew University;Department of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem; Liver Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Institute of Pathology, University Hospital Basel, Basel, Switzerland; Division of Signal Transduction and Growth Control (A100), Division of Molecular Genetics (B060), and Junior Group Molecular Mechanisms of Head and Neck Tumors (A102), German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance; Institute of Pathology, University Hospital Heidelberg; Departments of Otolaryngology, Head and Neck Surgery and Internal Medicine, University Hospital Heidelberg, Heidelberg; and Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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June 2014

Critical role for IL-1β in DNA damage-induced mucositis.

Proc Natl Acad Sci U S A 2014 Feb 27;111(6):E702-11. Epub 2014 Jan 27.

Lautenberg Centre for Immunology and Cancer Research, Institute for Medical Research Israel-Canada, Hebrew University Hadassah Medical School, Jerusalem 91120, Israel.

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February 2014

Genome-wide analysis of androgen receptor targets reveals COUP-TF1 as a novel player in human prostate cancer.

PLoS One 2012 4;7(10):e46467. Epub 2012 Oct 4.

Department of Pathology and Lautenberg center for immunology, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.

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June 2013

Regulation of NF-κB by ubiquitination and degradation of the IκBs.

Immunol Rev 2012 Mar;246(1):77-94

Lautenberg Centre for Immunology and Cancer Research, Institute for Medical Research Israel-Canada, The Hebrew University, Hadassah Medical School, Jerusalem, Israel.

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March 2012

mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR.

Mol Cell 2011 Oct;44(2):317-24

Department of Pathology, NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA.

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October 2011

Inflammation meets cancer, with NF-κB as the matchmaker.

Nat Immunol 2011 Jul 19;12(8):715-23. Epub 2011 Jul 19.

Lautenberg Center for Immunology, Institute for Medical Research-Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

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July 2011

Metalloprotease type III effectors that specifically cleave JNK and NF-κB.

EMBO J 2011 Jan 26;30(1):221-31. Epub 2010 Nov 26.

Department of Microbiology and Molecular Genetics, IMRIC, The Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, Israel.

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January 2011

Ubiquitination and degradation of the inhibitors of NF-kappaB.

Cold Spring Harb Perspect Biol 2010 Feb;2(2):a000166

Department of Immunology and Genetics and Biotechnology, Hebrew University-Hadassah Medical School, Institute of Medical Research Israel-Canada, Jerusalem, 91120, Israel.

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February 2010

beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor.

PLoS One 2010 Feb 5;5(2):e9060. Epub 2010 Feb 5.

Department of Pathology and the Lautenberg Center for Immunology, Hebrew University Hadassah Medical School, Jerusalem, Israel.

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February 2010

The type III secretion effector NleE inhibits NF-kappaB activation.

PLoS Pathog 2010 Jan 29;6(1):e1000743. Epub 2010 Jan 29.

Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel.

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January 2010

Design and synthesis of backbone cyclic phosphopeptides: the IkappaB model.

Adv Exp Med Biol 2009 ;611:139-40

Department of Organic Chemistry, The Hebrew University ofJerusalem, Jerusalem 91904, Israel.

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June 2009

Design and synthesis of backbone cyclic phosphorylated peptides: The IkappaB model.

Biopolymers 2009 Feb;91(2):157-68

Department of Organic Chemistry, Institute of Chemistry, The Hebrew University of Jerusalem, Israel.

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February 2009

Contradictory functions of NF-kappaB in liver physiology and cancer.

Cancer Lett 2008 Aug 13;267(2):182-8. Epub 2008 May 13.

Department of Pathology, Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.

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August 2008

Incensole acetate, a novel anti-inflammatory compound isolated from Boswellia resin, inhibits nuclear factor-kappa B activation.

Mol Pharmacol 2007 Dec 25;72(6):1657-64. Epub 2007 Sep 25.

Department of Medicinal Chemistry and Natural Products, Medical Faculty, Hebrew University, Jerusalem 91120, Israel.

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December 2007

Enhanced heat shock protein 70 expression alters proteasomal degradation of IkappaB kinase in experimental acute respiratory distress syndrome.

Crit Care Med 2007 Sep;35(9):2128-38

Department of Anesthesiology and Critical Care Medicine and the Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University School of Medicine, Jerusalem, Israel.

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September 2007

NF-kappaB inhibition: a double-edged sword in cancer?

Eur J Cancer 2006 Apr 10;42(6):779-84. Epub 2006 Mar 10.

Department of Pathology, Hebrew University Hadassah Medical School, Ein Kerem Campus, Kiryat Hadassah, Jerusalem 91120, Israel.

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April 2006

Inflammation and cancer: is the link as simple as we think?

J Invest Dermatol 2005 Jun;124(6):x-xiv

Oncology Institute, Cardinal Bernadin Cancer Center, Loyola University Chicago Medical Center, Chicago, Illinois, USA.

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June 2005

NFkappaB: Bench to Bedside - Keystone Symposium. 25 February - 3 March 2002, Keystone, CO, USA.

IDrugs 2002 Apr;5(4):331-5

The Lautenberg Center for Immunology, Hebrew University of Jerusalem Hadassah Medical School, Jerusalem 91120, Israel.

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April 2002

NF-kappaB functions as a tumour promoter in inflammation-associated cancer.

Nature 2004 Sep 25;431(7007):461-6. Epub 2004 Aug 25.

Department of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel.

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September 2004

Of mice and men.

EMBO Rep 2004 Jul 25;5(7):668-73. Epub 2004 Jun 25.

The Lautenberg Center for Immunology, Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.

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July 2004

Behind the scenes of anergy: a tale of three E3s.

Nat Immunol 2004 Mar;5(3):238-40

Lautenberg Center for Immunology, Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.

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March 2004

Pinning NF-kappaB to the nucleus.

Authors:
Yinon Ben-Neriah

Mol Cell 2003 Dec;12(6):1344-5

The Lautenberg Center for Immunology, Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.

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December 2003

Nuclear factor-kappaB protects the liver against genotoxic stress and functions independently of p53.

Cancer Res 2003 Jan;63(1):25-30

The Lautenberg Center for Immunology, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.

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January 2003

NF-kappaB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach.

Semin Cancer Biol 2003 Feb;13(1):15-28

The Lautenberg Center for Immunology, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.

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February 2003

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway.

Genes Dev 2002 May;16(9):1066-76

The Lautenberg Center for Immunology, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.

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May 2002

Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U.

Genes Dev 2002 Feb;16(4):439-51

The Lautenberg Center for Immunology, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.

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February 2002

Regulatory functions of ubiquitination in the immune system.

Authors:
Yinon Ben-Neriah

Nat Immunol 2002 Jan;3(1):20-6

The Lautenberg Center for Immunology, The Hebrew University-Hadassah Medical School, Jerusalem, 91120, Israel.

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January 2002