Yingyan Yu

Yingyan Yu

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Expression pattern of CDK12 protein in gastric cancer and its positive correlation with CD8 cell density and CCL12 expression.

Authors:
Jun Ji Chenfei Zhou Junwei Wu Qu Cai Min Shi Huan Zhang Yingyan Yu Zhenggang Zhu Jun Zhang

Int J Med Sci 2019 6;16(8):1142-1148. Epub 2019 Aug 6.

Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin er Road, Shanghai, 200025, China.

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http://www.medsci.org/v16p1142.htm
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http://dx.doi.org/10.7150/ijms.34541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743279PMC
August 2019

A positive feedback between IDO1 metabolite and COL12A1 via MAPK pathway to promote gastric cancer metastasis.

Authors:
Zhen Xiang Jun Li Shuzheng Song Jiexuan Wang Wei Cai Wenjun Hu Jun Ji Zhenggang Zhu Lu Zang Ranlin Yan Yingyan Yu

J Exp Clin Cancer Res 2019 Jul 17;38(1):314. Epub 2019 Jul 17.

Department of Surgery of Ruijin Hospital, and Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1186/s13046-019-1318-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637527PMC
July 2019

HUPAN: a pan-genome analysis pipeline for human genomes.

Authors:
Zhongqu Duan Yuyang Qiao Jinyuan Lu Huimin Lu Wenmin Zhang Fazhe Yan Chen Sun Zhiqiang Hu Zhen Zhang Guichao Li Hongzhuan Chen Zhen Xiang Zhenggang Zhu Hongyu Zhao Yingyan Yu Chaochun Wei

Genome Biol 2019 07 31;20(1):149. Epub 2019 Jul 31.

School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China.

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https://genomebiology.biomedcentral.com/articles/10.1186/s13
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http://dx.doi.org/10.1186/s13059-019-1751-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670167PMC
July 2019

Identification of discrepancy between CTLA4 expression and CTLA4 activation in gastric cancer.

Authors:
Zhen Xiang Wei Chen Jun Zhang Shuzheng Song Guang-Kai Xia Xin-Yu Huang Juan Xie Yingyan Yu Qing-Yuan Zhang

Immunopharmacol Immunotoxicol 2019 Jun 13;41(3):386-393. Epub 2018 Nov 13.

e Department of Gastrointestinal Surgery , The General Hospital of Ningxia Medical University , Yinchuan , China.

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https://www.tandfonline.com/doi/full/10.1080/08923973.2018.1
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http://dx.doi.org/10.1080/08923973.2018.1533968DOI Listing
June 2019

Whole-genome sequencing reveals novel tandem-duplication hotspots and a prognostic mutational signature in gastric cancer.

Authors:
Rui Xing Yong Zhou Jun Yu Yingyan Yu Yongzhan Nie Wen Luo Chao Yang Teng Xiong William K K Wu Zhongwu Li Yang Bing Shuye Lin Yaping Zhang Yingqi Hu Lin Li Lijuan Han Chen Yang Shaogang Huang Suiping Huang Rui Zhou Jing Li Kaichun Wu Daiming Fan Guangbo Tang Jianhua Dou Zhenggang Zhu Jiafu Ji Xiaodong Fang Youyong Lu

Nat Commun 2019 05 2;10(1):2037. Epub 2019 May 2.

Laboratory of Molecular Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, 100142, Beijing, China.

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http://dx.doi.org/10.1038/s41467-019-09644-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497673PMC
May 2019

A Novel Citrullinated Modification of Histone 3 and Its Regulatory Mechanisms Related to IPO-38 Antibody-Labeled Protein.

Authors:
Shuzheng Song Zhen Xiang Jun Li Jun Ji Ranlin Yan Zhenggang Zhu Yingyan Yu

Front Oncol 2019 18;9:304. Epub 2019 Apr 18.

Department of Surgery, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai, China.

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http://dx.doi.org/10.3389/fonc.2019.00304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482251PMC
April 2019

Screening responsive or resistant biomarkers of immune checkpoint inhibitors based on online databases.

Authors:
Zhen Xiang Yingyan Yu

Front Med 2019 Feb 18;13(1):24-31. Epub 2019 Jan 18.

Department of Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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http://dx.doi.org/10.1007/s11684-019-0679-7DOI Listing
February 2019

LncRNAs GIHCG and SPINT1-AS1 Are Crucial Factors for Pan-Cancer Cells Sensitivity to Lapatinib.

Authors:
Zhen Xiang Shuzheng Song Zhenggang Zhu Wenhong Sun Jaron E Gifts Sam Sun Qiushi Shauna Li Yingyan Yu Keqin Kathy Li

Front Genet 2019 19;10:25. Epub 2019 Feb 19.

Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA, United States.

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http://dx.doi.org/10.3389/fgene.2019.00025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391897PMC
February 2019

Progression on Citrullination of Proteins in Gastrointestinal Cancers.

Authors:
Shuzheng Song Yingyan Yu

Front Oncol 2019 23;9:15. Epub 2019 Jan 23.

Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai, China.

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http://dx.doi.org/10.3389/fonc.2019.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357933PMC
January 2019

Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer.

Authors:
Xinyu Liu Jun Zhang Lei Liu Yannan Jiang Jun Ji Ranlin Yan Zhenggang Zhu Yingyan Yu

Biochim Biophys Acta Mol Basis Dis 2018 09 23;1864(9 Pt B):2835-2844. Epub 2018 May 23.

Department of Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439183018
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http://dx.doi.org/10.1016/j.bbadis.2018.05.015DOI Listing
September 2018

Difference of molecular alterations in HER2-positive and HER2-negative gastric cancers by whole-genome sequencing analysis.

Authors:
Chenfei Zhou Xiaojing Feng Fei Yuan Jun Ji Min Shi Yingyan Yu Zhenggang Zhu Jun Zhang

Cancer Manag Res 2018 26;10:3945-3954. Epub 2018 Sep 26.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China,

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http://dx.doi.org/10.2147/CMAR.S172710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165778PMC
September 2018

HGF derived from cancer‑associated fibroblasts promotes vascularization in gastric cancer via PI3K/AKT and ERK1/2 signaling.

Authors:
Xusheng Ding Wenqi Xi Jun Ji Qu Cai Jinling Jiang Min Shi Yingyan Yu Zhenggang Zhu Jun Zhang

Oncol Rep 2018 Aug 18;40(2):1185-1195. Epub 2018 Jun 18.

Department of Oncology, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China.

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http://dx.doi.org/10.3892/or.2018.6500DOI Listing
August 2018

UBE2C Is a Potential Biomarker of Intestinal-Type Gastric Cancer With Chromosomal Instability.

Authors:
Jun Zhang Xinyu Liu Guanzhen Yu Lei Liu Jiejun Wang Xiaoyu Chen Yuhai Bian Yuan Ji Xiaoyan Zhou Yinan Chen Jun Ji Zhen Xiang Lei Guo Jingyuan Fang Yihong Sun Hui Cao Zhenggang Zhu Yingyan Yu

Front Pharmacol 2018 2;9:847. Epub 2018 Aug 2.

Department of Surgery, Ruijin Hospital, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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https://www.frontiersin.org/article/10.3389/fphar.2018.00847
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http://dx.doi.org/10.3389/fphar.2018.00847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082955PMC
August 2018

Cross-Database Analysis Reveals Sensitive Biomarkers for Combined Therapy for ERBB2+ Gastric Cancer.

Authors:
Zhen Xiang Xia Huang Jiexuan Wang Jun Zhang Jun Ji Ranlin Yan Zhenggang Zhu Wei Cai Yingyan Yu

Front Pharmacol 2018 3;9:861. Epub 2018 Aug 3.

Department of Surgery, Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai, China.

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https://www.frontiersin.org/article/10.3389/fphar.2018.00861
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http://dx.doi.org/10.3389/fphar.2018.00861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085474PMC
August 2018

HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis.

Authors:
Xusheng Ding Jun Ji Jinling Jiang Qu Cai Chao Wang Min Shi Yingyan Yu Zhenggang Zhu Jun Zhang

Cell Death Dis 2018 08 29;9(9):867. Epub 2018 Aug 29.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, China.

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http://dx.doi.org/10.1038/s41419-018-0922-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115420PMC
August 2018

Molecular classification and precision therapy of cancer: immune checkpoint inhibitors.

Authors:
Yingyan Yu

Front Med 2018 Apr 5;12(2):229-235. Epub 2017 Dec 5.

Department of Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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http://dx.doi.org/10.1007/s11684-017-0581-0DOI Listing
April 2018

Metronomic chemotherapy remodel cancer-associated fibroblasts to decrease chemoresistance of gastric cancer in nude mice.

Authors:
Chao Wang Wenqi Xi Jinling Jiang Jun Ji Yingyan Yu Zhenggang Zhu Jun Zhang

Oncol Lett 2017 Dec 16;14(6):7903-7909. Epub 2017 Oct 16.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China.

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http://dx.doi.org/10.3892/ol.2017.7197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755147PMC
December 2017

Pulmonary CCR2CD4 T cells are immune regulatory and attenuate lung fibrosis development.

Authors:
Katrin Milger Yingyan Yu Eva Brudy Martin Irmler Alla Skapenko Michael Mayinger Mareike Lehmann Johannes Beckers Frank Reichenberger Jürgen Behr Oliver Eickelberg Melanie Königshoff Susanne Krauss-Etschmann

Thorax 2017 11 5;72(11):1007-1020. Epub 2017 Aug 5.

Comprehensive Pneumology Center, Helmholtz Center Munich Germany, Member of the German Center for Lung Research (DZL), Munich, Germany.

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http://dx.doi.org/10.1136/thoraxjnl-2016-208423DOI Listing
November 2017

EGFR High Expression, but not KRAS Status, Predicts Sensitivity of Pancreatic Cancer Cells to Nimotuzumab Treatment In Vivo.

Authors:
Chenfei Zhou Liangjun Zhu Jun Ji Fangmi Ding Chao Wang Qu Cai Yingyan Yu Zhenggang Zhu Jun Zhang

Curr Cancer Drug Targets 2017 ;17(1):89-97

Department of Oncology, RuiJin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijiner Road, Shanghai 200025, China.

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http://dx.doi.org/10.2174/1568009616666161013101657DOI Listing
October 2017

MiR-148a Functions as a Tumor Suppressor by Targeting CCK-BR via Inactivating STAT3 and Akt in Human Gastric Cancer.

Authors:
Beiqin Yu Xin Lv Liping Su Jianfang Li Yingyan Yu Qinlong Gu Min Yan Zhenggang Zhu Bingya Liu

PLoS One 2016 12;11(8):e0158961. Epub 2016 Aug 12.

Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158961PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982598PMC
July 2017

A hydrophobic residue in the TALE homeodomain of PBX1 promotes epithelial-to-mesenchymal transition of gastric carcinoma.

Authors:
Changyu He Zhenqiang Wang Li Zhang Liyun Yang Jianfang Li Xuehua Chen Jun Zhang Qing Chang Yingyan Yu Bingya Liu Zhenggang Zhu

Oncotarget 2017 Jul;8(29):46818-46833

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.17473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564525PMC
July 2017

PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer.

Authors:
Chao Wang Jinling Jiang Jun Ji Qu Cai Xuehua Chen Yingyan Yu Zhenggang Zhu Jun Zhang

Sci Rep 2017 06 6;7(1):2886. Epub 2017 Jun 6.

Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, China.

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http://dx.doi.org/10.1038/s41598-017-03031-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460252PMC
June 2017

Fbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNU-induced gastric carcinogenesis.

Authors:
Yannan Jiang Xinming Qi Xinyu Liu Jun Zhang Jun Ji Zhenggang Zhu Jin Ren Yingyan Yu

Oncotarget 2017 May;8(20):33444-33456

Department of Surgery of Shanghai Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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http://dx.doi.org/10.18632/oncotarget.16800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464881PMC
May 2017

Deubiquitinating enzyme USP20 is a positive regulator of Claspin and suppresses the malignant characteristics of gastric cancer cells.

Authors:
Chao Wang Chen Yang Jun Ji Jinling Jiang Min Shi Qu Cai Yingyan Yu Zhenggang Zhu Jun Zhang

Int J Oncol 2017 Mar 8. Epub 2017 Mar 8.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China.

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http://dx.doi.org/10.3892/ijo.2017.3904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363881PMC
March 2017

Transgenic and gene knockout mice in gastric cancer research.

Authors:
Yannan Jiang Yingyan Yu

Oncotarget 2017 Jan;8(2):3696-3710

Department of Surgery of Ruijin Hospital and Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.12467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356912PMC
January 2017

A characteristic biosignature for discrimination of gastric cancer from healthy population by high throughput GC-MS analysis.

Authors:
Yinan Chen Jun Zhang Lei Guo Lei Liu Jingran Wen Lu Xu Min Yan Zuofeng Li Xiaoyan Zhang Peng Nan Jinling Jiang Jun Ji Jianian Zhang Wei Cai Huisheng Zhuang Yan Wang Zhenggang Zhu Yingyan Yu

Oncotarget 2016 Dec;7(52):87496-87510

Department of Surgery of Ruijin Hospital, and Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.11754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350005PMC
December 2016

DBGC: A Database of Human Gastric Cancer.

Authors:
Chao Wang Jun Zhang Mingdeng Cai Zhenggang Zhu Wenjie Gu Yingyan Yu Xiaoyan Zhang

PLoS One 2015 13;10(11):e0142591. Epub 2015 Nov 13.

School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0142591PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643992PMC
July 2016

Mitochondrial aldehyde dehydrogenase 2 protects gastric mucosa cells against DNA damage caused by oxidative stress.

Authors:
Yantao Duan Yaohui Gao Jun Zhang Yinan Chen Yannan Jiang Jun Ji Jianian Zhang Xuehua Chen Qiumeng Yang Liping Su Jun Zhang Bingya Liu Zhenggang Zhu Lishun Wang Yingyan Yu

Free Radic Biol Med 2016 Apr 5;93:165-76. Epub 2016 Feb 5.

Department of Surgery, Ruijin Hospital, Shanghai Institute of Digestive Surgery and Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin er Road, Shanghai 200025, People's Republic of China; Collaborative Innovation Center of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200025, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.02.001DOI Listing
April 2016

Stomach virtual non-enhanced CT with second-generation, dual-energy CT: a preliminary study.

Authors:
Lei Shi Fuhua Yan Zilai Pan Bo Liu Huanhuan Liu Baisong Wang Huan Zhang Yingyan Yu

PLoS One 2014 13;9(11):e112295. Epub 2014 Nov 13.

Shanghai Institute of Digestive Surgery, Shanghai Jiaotong University School of Medicine, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112295PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231030PMC
January 2016

Silencing NKD2 by promoter region hypermethylation promotes gastric cancer invasion and metastasis by up-regulating SOX18 in human gastric cancer.

Authors:
Yan Jia Baoping Cao Yunsheng Yang Enqiang Linghu Qimin Zhan Youyong Lu Yingyan Yu James G Herman Mingzhou Guo

Oncotarget 2015 Oct;6(32):33470-85

Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, Beijing 100853, China.

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http://www.oncotarget.com/fulltext/5272
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http://dx.doi.org/10.18632/oncotarget.5272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741779PMC
October 2015

Cetuximab inhibits gastric cancer growth in vivo, independent of KRAS status.

Authors:
Min Shi Hailong Shi Jun Ji Qu Cai Xuehua Chen Yingyan Yu Bingya Liu Zhenggang Zhu Jun Zhang

Curr Cancer Drug Targets 2014 ;14(2):217-24

Departments of Surgery and Clinical Oncology, Shanghai Institute of Digestive Surgery, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China.

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http://dx.doi.org/10.2174/1570163811666140127145031DOI Listing
June 2015

KRAS and DAXX/ATRX gene mutations are correlated with the clinicopathological features, advanced diseases, and poor prognosis in Chinese patients with pancreatic neuroendocrine tumors.

Authors:
Fei Yuan Min Shi Jun Ji Hailong Shi Chenfei Zhou Yingyan Yu Bingya Liu Zhenggang Zhu Jun Zhang

Int J Biol Sci 2014 30;10(9):957-65. Epub 2014 Aug 30.

1. Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China; ; 2. Department of Clinical Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China;

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http://dx.doi.org/10.7150/ijbs.9773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159686PMC
May 2015

MTA2 enhances colony formation and tumor growth of gastric cancer cells through IL-11.

Authors:
Chenfei Zhou Jun Ji Qu Cai Min Shi Xuehua Chen Yingyan Yu Zhenggang Zhu Jun Zhang

BMC Cancer 2015 May 2;15:343. Epub 2015 May 2.

Department of Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin er Road, Shanghai, 200025, China.

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http://bmccancer.biomedcentral.com/articles/10.1186/s12885-0
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http://dx.doi.org/10.1186/s12885-015-1366-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419442PMC
May 2015

Capecitabine metronomic chemotherapy inhibits the proliferation of gastric cancer cells through anti-angiogenesis.

Authors:
Fei Yuan Hailong Shi Jun Ji Qu Cai Xuehua Chen Yingyan Yu Bingya Liu Zhenggang Zhu Jun Zhang

Oncol Rep 2015 Apr 29;33(4):1753-62. Epub 2015 Jan 29.

Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China.

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http://dx.doi.org/10.3892/or.2015.3765DOI Listing
April 2015

Pin1 is overexpressed and correlates with poor prognosis in gastric cancer.

Authors:
Min Shi Lingxiang Chen Jun Ji Qu Cai Yingyan Yu Bingya Liu Zhenggang Zhu Jun Zhang

Cell Biochem Biophys 2015 Mar;71(2):857-64

Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin er Road, Shanghai, 200025, China.

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http://dx.doi.org/10.1007/s12013-014-0274-0DOI Listing
March 2015

Rac1 is correlated with aggressiveness and a potential therapeutic target for gastric cancer.

Authors:
Jun Ji Xiaojing Feng Min Shi Qu Cai Yingyan Yu Zhenggang Zhu Jun Zhang

Int J Oncol 2015 Mar 13;46(3):1343-53. Epub 2015 Jan 13.

Department of Clinical Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China.

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http://dx.doi.org/10.3892/ijo.2015.2836DOI Listing
March 2015

The important molecular markers on chromosome 17 and their clinical impact in breast cancer.

Authors:
Wei Zhang Yingyan Yu

Int J Mol Sci 2011 5;12(9):5672-83. Epub 2011 Sep 5.

Department of Surgery, School of Medicine, The Ninth People's Hospital of Shanghai Jiao Tong University, Shanghai 200011, China.

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http://dx.doi.org/10.3390/ijms12095672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189742PMC
February 2015

Reactivation of HIC-1 gene by saRNA inhibits clonogenicity and invasiveness in breast cancer cells.

Authors:
Feng Zhao Shengli Pan Yan Gu Shanyu Guo Qiancheng Dai Yingyan Yu Wei Zhang

Oncol Lett 2015 Jan 24;9(1):159-164. Epub 2014 Oct 24.

Department of Surgery, The Ninth People's Hospital of Shanghai Jiao Tong University, School of Medicine, Shanghai 200011, P.R. China.

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http://dx.doi.org/10.3892/ol.2014.2633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246611PMC
January 2015

Claudin-1 enhances tumor proliferation and metastasis by regulating cell anoikis in gastric cancer.

Authors:
Jie Huang Li Zhang Changyu He Ying Qu Jianfang Li Jianian Zhang Tao Du Xuehua Chen Yingyan Yu Bingya Liu Zhenggang Zhu

Oncotarget 2015 Jan;6(3):1652-65

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359322PMC
http://dx.doi.org/10.18632/oncotarget.2936DOI Listing
January 2015

[Bioinformatics of tumor molecular targets from big data].

Authors:
Jinyan Huang Yingyan Yu

Zhonghua Wei Chang Wai Ke Za Zhi 2015 Jan;18(1):9-12

Shanghai Institute of Digestive Surgery, Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

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January 2015

Small activating RNA restores the activity of the tumor suppressor HIC-1 on breast cancer.

Authors:
Feng Zhao Shengli Pan Yan Gu Shanyu Guo Qiancheng Dai Yingyan Yu Wei Zhang

PLoS One 2014 28;9(1):e86486. Epub 2014 Jan 28.

Department of Surgery, The Ninth People's Hospital of Shanghai Jiao Tong University, School of Medicine, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086486PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904905PMC
December 2014

Identification of differentially-expressed genes in intestinal gastric cancer by microarray analysis.

Authors:
Shizhu Zang Ruifang Guo Rui Xing Liang Zhang Wenmei Li Min Zhao Jingyuan Fang Fulian Hu Bin Kang Yonghong Ren Yonglong Zhuang Siqi Liu Rong Wang Xianghong Li Yingyan Yu Jing Cheng Youyong Lu

Genomics Proteomics Bioinformatics 2014 Dec 11;12(6):276-83. Epub 2014 Dec 11.

Laboratory of Molecular Oncology, MOE Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Beijing 100142, China. Electronic address:

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http://dx.doi.org/10.1016/j.gpb.2014.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411479PMC
December 2014

DACT2 is frequently methylated in human gastric cancer and methylation of DACT2 activated Wnt signaling.

Authors:
Yuanzi Yu Wenji Yan Xuefeng Liu Yan Jia Baoping Cao Yingyan Yu Youyong Lv Malcolm V Brock Jame G Herman Julien Licchesi Yunsheng Yang Mingzhou Guo

Am J Cancer Res 2014 19;4(6):710-24. Epub 2014 Nov 19.

Department of Gastroenterology and Hepatology, Chinese PLA General Hospital #28 Fuxing Road, Beijing 100853, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266706PMC
December 2014

Suberoylanilide hydroxamic acid enhances the antitumor activity of oxaliplatin by reversing the oxaliplatin‑induced Src activation in gastric cancer cells.

Authors:
Chenfei Zhou Jun Ji Min Shi Liu Yang Yingyan Yu Bingya Liu Zhenggang Zhu Jun Zhang

Mol Med Rep 2014 Nov 9;10(5):2729-35. Epub 2014 Sep 9.

Department of Surgery, Shanghai Institute of Digestive Surgery, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China.

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http://dx.doi.org/10.3892/mmr.2014.2548DOI Listing
November 2014

Novel methodologies in analysis of small molecule biomarkers and living cells.

Authors:
Yinan Chen Zhenggang Zhu Yingyan Yu

Tumour Biol 2014 Oct 14;35(10):9469-77. Epub 2014 Aug 14.

Department of Surgery, Shanghai Institute of Digestive Surgery, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Ruijin er Road, No. 197, 200025, Shanghai, China.

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http://link.springer.com/10.1007/s13277-014-2439-2
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October 2014

Anti-angiogenesis participates in antitumor effects of metronomic capecitabine on colon cancer.

Authors:
Hailong Shi Jinling Jiang Jun Ji Min Shi Qu Cai Xuehua Chen Yingyan Yu Bingya Liu Zhenggang Zhu Jun Zhang

Cancer Lett 2014 Jul 16;349(2):128-35. Epub 2014 Apr 16.

Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China; Department of Clinical Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.04.002DOI Listing
July 2014

Tumor suppressor miR-24 restrains gastric cancer progression by downregulating RegIV.

Authors:
Yantao Duan Lei Hu Bing Liu Beiqin Yu Jianfang Li Min Yan Yingyan Yu Chen Li Liping Su Zhenggang Zhu Ming Xiang Bingya Liu Qiumeng Yang

Mol Cancer 2014 May 28;13:127. Epub 2014 May 28.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No 197 Ruijin er Road, Shanghai 200025, People's Republic of China.

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http://dx.doi.org/10.1186/1476-4598-13-127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041902PMC
May 2014

[Application of genetically engineered mice model in the research of gastrointestinal tumor].

Authors:
Yannan Jiang Yingyan Yu

Zhonghua Wei Chang Wai Ke Za Zhi 2014 Apr;17(4):407-10

Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

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April 2014

Decrease of miR-202-3p expression, a novel tumor suppressor, in gastric cancer.

Authors:
Yu Zhao Chenglong Li Ming Wang Liping Su Ying Qu Jianfang Li Beiqin Yu Min Yan Yingyan Yu Bingya Liu Zhenggang Zhu

PLoS One 2013 25;8(7):e69756. Epub 2013 Jul 25.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069756PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723650PMC
March 2014

Epigenetic silencing of miR-338-3p contributes to tumorigenicity in gastric cancer by targeting SSX2IP.

Authors:
Pu Li Xuehua Chen Liping Su Chenglong Li Qiaoming Zhi Beiqin Yu Hong Sheng Junqing Wang Runhua Feng Qu Cai Jianfang Li Yingyan Yu Min Yan Bingya Liu Zhenggang Zhu

PLoS One 2013 24;8(6):e66782. Epub 2013 Jun 24.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066782PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691322PMC
January 2014

Integrity of the LXXLL motif in Stat6 is required for the inhibition of breast cancer cell growth and enhancement of differentiation in the context of progesterone.

Authors:
Min Wei Qi He Zhongyin Yang Zhiwei Wang Qing Zhang Bingya Liu Qinlong Gu Liping Su Yingyan Yu Zhenggang Zhu Guofeng Zhang

BMC Cancer 2014 Jan 8;14:10. Epub 2014 Jan 8.

Breast Department, International Peace Maternity and Child Health Hospital, Shanghai Jiaotong University, Shanghai 200030, People's Republic of China.

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http://dx.doi.org/10.1186/1471-2407-14-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021501PMC
January 2014

MiR-133b is frequently decreased in gastric cancer and its overexpression reduces the metastatic potential of gastric cancer cells.

Authors:
Yu Zhao Jie Huang Li Zhang Ying Qu Jianfang Li Beiqin Yu Min Yan Yingyan Yu Bingya Liu Zhenggang Zhu

BMC Cancer 2014 Jan 21;14:34. Epub 2014 Jan 21.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Rui Jin Road, Shanghai 200025, People's Republic of China.

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http://dx.doi.org/10.1186/1471-2407-14-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925791PMC
January 2014

[Evaluation of traditional pathological classification at molecular classification era for gastric cancer].

Authors:
Yingyan Yu

Zhonghua Wei Chang Wai Ke Za Zhi 2014 Jan;17(1):18-20

Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

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January 2014

CRKL promotes cell proliferation in gastric cancer and is negatively regulated by miR-126.

Authors:
Junqing Wang Xuehua Chen Pu Li Liping Su Beiqin Yu Qu Cai Jianfang Li Yingyan Yu Bingya Liu Zhenggang Zhu

Chem Biol Interact 2013 Nov 18;206(2):230-8. Epub 2013 Sep 18.

Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, 197 Rui Jin Er Road, Shanghai 20025, People's Republic of China; Shanghai Key Laboratory of Gastric Neoplasms, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, 197 Rui Jin Er Road, Shanghai 20025, People's Republic of China; Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, 197 Rui Jin Er Road, Shanghai 20025, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2013.09.003DOI Listing
November 2013

Overexpressed miR-301a promotes cell proliferation and invasion by targeting RUNX3 in gastric cancer.

Authors:
Ming Wang Chenglong Li Beiqin Yu Liping Su Jianfang Li Jingfang Ju Yingyan Yu Qinlong Gu Zhenggang Zhu Bingya Liu

J Gastroenterol 2013 Sep 22;48(9):1023-33. Epub 2013 Jan 22.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, 197# Ruijin Er Road, Shanghai, 200025, People's Republic of China.

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http://link.springer.com/10.1007/s00535-012-0733-6
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September 2013

Inactivation of tumor suppressor gene HIC1 in gastric cancer is reversed via small activating RNAs.

Authors:
Shengli Pan Zhiwei Wang Yinan Chen Xuehua Chen Jun Ji Jianian Zhang Jianfang Li Qu Cai Bingya Liu Zhenggang Zhu Yingyan Yu

Gene 2013 Sep 12;527(1):102-8. Epub 2013 Jun 12.

Department of Surgery, Shanghai Institute of Digestive Surgery, Shanghai Ruijin Hospital, Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University, School of Medicine, Ruijin er Road, No. 197, 200025 Shanghai, China.

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http://dx.doi.org/10.1016/j.gene.2013.05.034DOI Listing
September 2013

MTA2 promotes gastric cancer cells invasion and is transcriptionally regulated by Sp1.

Authors:
Chenfei Zhou Jun Ji Qu Cai Min Shi Xuehua Chen Yingyan Yu Bingya Liu Zhenggang Zhu Jun Zhang

Mol Cancer 2013 Sep 8;12(1):102. Epub 2013 Sep 8.

Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No, 197 Ruijin er Road, Shanghai 200025, P,R, China.

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http://dx.doi.org/10.1186/1476-4598-12-102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851872PMC
September 2013

Hepatocyte growth factor activates tumor stromal fibroblasts to promote tumorigenesis in gastric cancer.

Authors:
Xiongyan Wu Xuehua Chen Quan Zhou Pu Li Beiqin Yu Jianfang Li Ying Qu Jun Yan Yingyan Yu Min Yan Zhenggang Zhu Bingya Liu Liping Su

Cancer Lett 2013 Jul 9;335(1):128-35. Epub 2013 Feb 9.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, PR China.

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https://linkinghub.elsevier.com/retrieve/pii/S03043835130011
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http://dx.doi.org/10.1016/j.canlet.2013.02.002DOI Listing
July 2013

Synergistic antitumor effects of dasatinib and oxaliplatin in gastric cancer cells.

Authors:
Min Shi Bingxiang Lou Jun Ji Hailong Shi Chenfei Zhou Yingyan Yu Bingya Liu Zhenggang Zhu Jun Zhang

Cancer Chemother Pharmacol 2013 Jul 28;72(1):35-44. Epub 2013 May 28.

Department of Surgery, Shanghai Institute of Digestive Surgery, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin er Road, Shanghai, 200025, People's Republic of China.

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http://dx.doi.org/10.1007/s00280-013-2166-1DOI Listing
July 2013

Osteopontin splice variants differentially exert clinicopathological features and biological functions in gastric cancer.

Authors:
Xiaojian Tang Jianfang Li Beiqin Yu Liping Su Yingyan Yu Min Yan Bingya Liu Zhenggang Zhu

Int J Biol Sci 2013 20;9(1):55-66. Epub 2012 Dec 20.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Rui Jin Er Road, Shanghai 200025, People's Republic of China.

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http://dx.doi.org/10.7150/ijbs.5280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535534PMC
June 2013

A unique feature of iron loss via close adhesion of Helicobacter pylori to host erythrocytes.

Authors:
Zhiwei Wang Lijuan Zhang Zhi Guo Lei Liu Jun Ji Jianian Zhang Xuehua Chen Bingya Liu Jun Zhang Qiulan Ding Xuefeng Wang Wei Zhao Zhenggang Zhu Yingyan Yu

PLoS One 2012 21;7(11):e50314. Epub 2012 Nov 21.

Shanghai Institute of Digestive Surgery and Department of Surgery, Shanghai Ruijin Hospital, Shanghai Key Laboratory for Gastric Neoplasia, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050314PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503993PMC
May 2013

Stromal fibroblasts in the microenvironment of gastric carcinomas promote tumor metastasis via upregulating TAGLN expression.

Authors:
Beiqin Yu Xuehua Chen Jianfang Li Ying Qu Liping Su Yibing Peng Jian Huang Jun Yan Yingyan Yu Qinlong Gu Zhenggang Zhu Bingya Liu

BMC Cell Biol 2013 Mar 19;14:17. Epub 2013 Mar 19.

Key Laboratory of Shanghai Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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http://dx.doi.org/10.1186/1471-2121-14-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610155PMC
March 2013

Oncogenic miR-544 is an important molecular target in gastric cancer.

Authors:
Qiaoming Zhi Xiaobo Guo Lei Guo Rongjuan Zhang Jinling Jiang Jun Ji Jianian Zhang Jun Zhang Xuehua Chen Qu Cai Jianfang Li Bingya Liu Zhenggang Zhu Yingyan Yu

Anticancer Agents Med Chem 2013 Feb;13(2):270-5

Department of Surgery of Ruijin Hospital, Shanghai Key Laboratory for Gastric Neoplasia, Affiliated to Shanghai Jiao Tong University, School of Medicine, Ruijin er Road, No. 197, 200025, Shanghai, China.

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http://dx.doi.org/10.2174/1871520611313020013DOI Listing
February 2013

A sample selection strategy to boost the statistical power of signature detection in cancer expression profile studies.

Authors:
Zhenyu Jia Yipeng Wang Yuanjie Hu Christine McLaren Yingyan Yu Kai Ye Xiao-Qin Xia James A Koziol Waldemar Lernhardt Michael McClelland Dan Mercola

Anticancer Agents Med Chem 2013 Feb;13(2):203-11

Department of Pathology and Laboratory Medicine, University of California, Irvine, CA 92697, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786411PMC
http://dx.doi.org/10.2174/1871520611313020004DOI Listing
February 2013

Editorial: translational medicine is promoting cross-talk of inter discipline.

Authors:
Yingyan Yu

Anticancer Agents Med Chem 2013 Feb;13(2):193-4

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http://dx.doi.org/10.2174/1871520611313020001DOI Listing
February 2013

Stat6 cooperates with Sp1 in controlling breast cancer cell proliferation by modulating the expression of p21(Cip1/WAF1) and p27 (Kip1).

Authors:
Min Wei Bingya Liu Qinlong Gu Liping Su Yingyan Yu Zhenggang Zhu

Cell Oncol (Dordr) 2013 Feb 27;36(1):79-93. Epub 2012 Nov 27.

Breast Department, International Peace Maternity and Child Health Hospital, Shanghai Jiaotong University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1007/s13402-012-0115-3DOI Listing
February 2013

ABO blood group system and gastric cancer: a case-control study and meta-analysis.

Authors:
Zhiwei Wang Lei Liu Jun Ji Jianian Zhang Min Yan Jun Zhang Bingya Liu Zhenggang Zhu Yingyan Yu

Int J Mol Sci 2012 Oct 17;13(10):13308-21. Epub 2012 Oct 17.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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http://dx.doi.org/10.3390/ijms131013308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497328PMC
October 2012

MicroRNA-409-3p regulates cell proliferation and apoptosis by targeting PHF10 in gastric cancer.

Authors:
Chenglong Li Hui Nie Ming Wang Liping Su Jianfang Li Beiqin Yu Min Wei Jingfang Ju Yingyan Yu Min Yan Qinlong Gu Zhenggang Zhu Bingya Liu

Cancer Lett 2012 Jul 1;320(2):189-97. Epub 2012 Mar 1.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

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https://linkinghub.elsevier.com/retrieve/pii/S03043835120014
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http://dx.doi.org/10.1016/j.canlet.2012.02.030DOI Listing
July 2012

Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK.

Authors:
Ming Wang Chenglong Li Hui Nie Xin Lv Ying Qu Beiqin Yu Liping Su Jianfang Li Xuehua Chen Jingfang Ju Yingyan Yu Min Yan Qinlong Gu Zhenggang Zhu Bingya Liu

FEBS Lett 2012 Jul 4;586(16):2382-8. Epub 2012 Jun 4.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197# Ruijin Er Road, Shanghai 200025, People's Republic of China.

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http://dx.doi.org/10.1016/j.febslet.2012.05.050DOI Listing
July 2012

Hypermethylated FAM5C and MYLK in serum as diagnosis and pre-warning markers for gastric cancer.

Authors:
Lu Chen Liping Su Jianfang Li Yanan Zheng Beiqin Yu Yingyan Yu Min Yan Qinlong Gu Zhenggang Zhu Bingya Liu

Dis Markers 2012 ;32(3):195-202

Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.3233/DMA-2011-0877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826591PMC
June 2012

Hypermethylated DNA as potential biomarkers for gastric cancer diagnosis.

Authors:
Yanan Zheng Lu Chen Jianfang Li Beiqin Yu Liping Su Xuehua Chen Yingyan Yu Min Yan Bingya Liu Zhenggang Zhu

Clin Biochem 2011 Dec 16;44(17-18):1405-11. Epub 2011 Sep 16.

Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, People's Republic of China.

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http://dx.doi.org/10.1016/j.clinbiochem.2011.09.006DOI Listing
December 2011

P27(Kip1), regulated by glycogen synthase kinase-3β, results in HMBA-induced differentiation of human gastric cancer cells.

Authors:
Min Wei Zhiwei Wang Hongliang Yao Zhongyin Yang Qing Zhang Bingya Liu Yingyan Yu Liping Su Zhenggang Zhu Qinlong Gu

BMC Cancer 2011 Mar 27;11:109. Epub 2011 Mar 27.

Key Laboratory of Shanghai Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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http://dx.doi.org/10.1186/1471-2407-11-109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078896PMC
March 2011

miR-126 functions as a tumour suppressor in human gastric cancer.

Authors:
Runhua Feng Xuehua Chen Yingyan Yu Liping Su Beiqin Yu Jianfang Li Qu Cai Min Yan Bingya Liu Zhenggang Zhu

Cancer Lett 2010 Dec 8;298(1):50-63. Epub 2010 Jul 8.

Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Rui Jin Er Road, Shanghai 20025, People's Republic of China.

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http://dx.doi.org/10.1016/j.canlet.2010.06.004DOI Listing
December 2010

Possible involvements of nuclear factor-kappa B and activator protein-1 in the tumor necrosis factor-alpha-induced upregulation of matrix metalloproteinase-12 in human alveolar epithelial A549 cell line.

Authors:
Yingyan Yu Yoshihiko Chiba Hiroyasu Sakai Miwa Misawa

J Pharmacol Sci 2010 6;112(1):83-8. Epub 2010 Jan 6.

Department of Pharmacology, School of Pharmacy, Hoshi University, Japan.

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http://dx.doi.org/10.1254/jphs.09268fpDOI Listing
September 2010

miRNA-331-3p directly targets E2F1 and induces growth arrest in human gastric cancer.

Authors:
Xiaobo Guo Lei Guo Jun Ji Jianian Zhang Jun Zhang Xuehua Chen Qu Cai Jianfang Li Qinlong Gu Bingya Liu Zhenggang Zhu Yingyan Yu

Biochem Biophys Res Commun 2010 Jul 16;398(1):1-6. Epub 2010 May 16.

Department of Surgery, Shanghai Ruijin Hospital, Shanghai Institute of Digestive Surgery, Shanghai Jiao Tong University School of Medicine, 200025 Shanghai, China.

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http://dx.doi.org/10.1016/j.bbrc.2010.05.082DOI Listing
July 2010

Effect of a matrix metalloproteinase-12 inhibitor, S-1, on allergic airway disease phenotypes in mice.

Authors:
Yingyan Yu Yoshihiko Chiba Hiroyasu Sakai Miwa Misawa

Inflamm Res 2010 Jun 12;59(6):419-28. Epub 2010 Jan 12.

Department of Pharmacology, School of Pharmacy, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.

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http://dx.doi.org/10.1007/s00011-009-0153-0DOI Listing
June 2010

A novel plant homeodomain finger 10-mediated antiapoptotic mechanism involving repression of caspase-3 in gastric cancer cells.

Authors:
Min Wei Bingya Liu Liping Su Jianfang Li Jun Zhang Yingyan Yu Min Yan Zhongyin Yang Xuehua Chen Jiayun Liu Xin Lv Hui Nie Qing Zhang Zhong Zheng Beiqin Yu Jun Ji Jianian Zhang Zhenggang Zhu Qinlong Gu

Mol Cancer Ther 2010 Jun 8;9(6):1764-74. Epub 2010 Jun 8.

Department of General Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1158/1535-7163.MCT-09-1162DOI Listing
June 2010

International network of cancer genome projects.

Authors:
Thomas J Hudson Warwick Anderson Axel Artez Anna D Barker Cindy Bell Rosa R Bernabé M K Bhan Fabien Calvo Iiro Eerola Daniela S Gerhard Alan Guttmacher Mark Guyer Fiona M Hemsley Jennifer L Jennings David Kerr Peter Klatt Patrik Kolar Jun Kusada David P Lane Frank Laplace Lu Youyong Gerd Nettekoven Brad Ozenberger Jane Peterson T S Rao Jacques Remacle Alan J Schafer Tatsuhiro Shibata Michael R Stratton Joseph G Vockley Koichi Watanabe Huanming Yang Matthew M F Yuen Bartha M Knoppers Martin Bobrow Anne Cambon-Thomsen Lynn G Dressler Stephanie O M Dyke Yann Joly Kazuto Kato Karen L Kennedy Pilar Nicolás Michael J Parker Emmanuelle Rial-Sebbag Carlos M Romeo-Casabona Kenna M Shaw Susan Wallace Georgia L Wiesner Nikolajs Zeps Peter Lichter Andrew V Biankin Christian Chabannon Lynda Chin Bruno Clément Enrique de Alava Françoise Degos Martin L Ferguson Peter Geary D Neil Hayes Thomas J Hudson Amber L Johns Arek Kasprzyk Hidewaki Nakagawa Robert Penny Miguel A Piris Rajiv Sarin Aldo Scarpa Tatsuhiro Shibata Marc van de Vijver P Andrew Futreal Hiroyuki Aburatani Mónica Bayés David D L Botwell Peter J Campbell Xavier Estivill Daniela S Gerhard Sean M Grimmond Ivo Gut Martin Hirst Carlos López-Otín Partha Majumder Marco Marra John D McPherson Hidewaki Nakagawa Zemin Ning Xose S Puente Yijun Ruan Tatsuhiro Shibata Michael R Stratton Hendrik G Stunnenberg Harold Swerdlow Victor E Velculescu Richard K Wilson Hong H Xue Liu Yang Paul T Spellman Gary D Bader Paul C Boutros Peter J Campbell Paul Flicek Gad Getz Roderic Guigó Guangwu Guo David Haussler Simon Heath Tim J Hubbard Tao Jiang Steven M Jones Qibin Li Nuria López-Bigas Ruibang Luo Lakshmi Muthuswamy B F Francis Ouellette John V Pearson Xose S Puente Victor Quesada Benjamin J Raphael Chris Sander Tatsuhiro Shibata Terence P Speed Lincoln D Stein Joshua M Stuart Jon W Teague Yasushi Totoki Tatsuhiko Tsunoda Alfonso Valencia David A Wheeler Honglong Wu Shancen Zhao Guangyu Zhou Lincoln D Stein Roderic Guigó Tim J Hubbard Yann Joly Steven M Jones Arek Kasprzyk Mark Lathrop Nuria López-Bigas B F Francis Ouellette Paul T Spellman Jon W Teague Gilles Thomas Alfonso Valencia Teruhiko Yoshida Karen L Kennedy Myles Axton Stephanie O M Dyke P Andrew Futreal Daniela S Gerhard Chris Gunter Mark Guyer Thomas J Hudson John D McPherson Linda J Miller Brad Ozenberger Kenna M Shaw Arek Kasprzyk Lincoln D Stein Junjun Zhang Syed A Haider Jianxin Wang Christina K Yung Anthony Cros Anthony Cross Yong Liang Saravanamuttu Gnaneshan Jonathan Guberman Jack Hsu Martin Bobrow Don R C Chalmers Karl W Hasel Yann Joly Terry S H Kaan Karen L Kennedy Bartha M Knoppers William W Lowrance Tohru Masui Pilar Nicolás Emmanuelle Rial-Sebbag Laura Lyman Rodriguez Catherine Vergely Teruhiko Yoshida Sean M Grimmond Andrew V Biankin David D L Bowtell Nicole Cloonan Anna deFazio James R Eshleman Dariush Etemadmoghadam Brooke B Gardiner Brooke A Gardiner James G Kench Aldo Scarpa Robert L Sutherland Margaret A Tempero Nicola J Waddell Peter J Wilson John D McPherson Steve Gallinger Ming-Sound Tsao Patricia A Shaw Gloria M Petersen Debabrata Mukhopadhyay Lynda Chin Ronald A DePinho Sarah Thayer Lakshmi Muthuswamy Kamran Shazand Timothy Beck Michelle Sam Lee Timms Vanessa Ballin Youyong Lu Jiafu Ji Xiuqing Zhang Feng Chen Xueda Hu Guangyu Zhou Qi Yang Geng Tian Lianhai Zhang Xiaofang Xing Xianghong Li Zhenggang Zhu Yingyan Yu Jun Yu Huanming Yang Mark Lathrop Jörg Tost Paul Brennan Ivana Holcatova David Zaridze Alvis Brazma Lars Egevard Egor Prokhortchouk Rosamonde Elizabeth Banks Mathias Uhlén Anne Cambon-Thomsen Juris Viksna Fredrik Ponten Konstantin Skryabin Michael R Stratton P Andrew Futreal Ewan Birney Ake Borg Anne-Lise Børresen-Dale Carlos Caldas John A Foekens Sancha Martin Jorge S Reis-Filho Andrea L Richardson Christos Sotiriou Hendrik G Stunnenberg Giles Thoms Marc van de Vijver Laura van't Veer Fabien Calvo Daniel Birnbaum Hélène Blanche Pascal Boucher Sandrine Boyault Christian Chabannon Ivo Gut Jocelyne D Masson-Jacquemier Mark Lathrop Iris Pauporté Xavier Pivot Anne Vincent-Salomon Eric Tabone Charles Theillet Gilles Thomas Jörg Tost Isabelle Treilleux Fabien Calvo Paulette Bioulac-Sage Bruno Clément Thomas Decaens Françoise Degos Dominique Franco Ivo Gut Marta Gut Simon Heath Mark Lathrop Didier Samuel Gilles Thomas Jessica Zucman-Rossi Peter Lichter Roland Eils Benedikt Brors Jan O Korbel Andrey Korshunov Pablo Landgraf Hans Lehrach Stefan Pfister Bernhard Radlwimmer Guido Reifenberger Michael D Taylor Christof von Kalle Partha P Majumder Rajiv Sarin T S Rao M K Bhan Aldo Scarpa Paolo Pederzoli Rita A Lawlor Massimo Delledonne Alberto Bardelli Andrew V Biankin Sean M Grimmond Thomas Gress David Klimstra Giuseppe Zamboni Tatsuhiro Shibata Yusuke Nakamura Hidewaki Nakagawa Jun Kusada Tatsuhiko Tsunoda Satoru Miyano Hiroyuki Aburatani Kazuto Kato Akihiro Fujimoto Teruhiko Yoshida Elias Campo Carlos López-Otín Xavier Estivill Roderic Guigó Silvia de Sanjosé Miguel A Piris Emili 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