Ying-Ta Wu

Ying-Ta Wu

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Ying-Ta Wu

Ying-Ta Wu

Publications by authors named "Ying-Ta Wu"

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27Publications

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Structure-based design of bacterial transglycosylase inhibitors incorporating biphenyl, amine linker and 2-alkoxy-3-phosphorylpropanoate moieties.

Eur J Med Chem 2018 Apr 15;150:729-741. Epub 2018 Mar 15.

Department of Chemistry, National Taiwan University, Taipei, 106, Taiwan, ROC; The Genomics Research Center, Academia Sinica, Taipei, 115, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.03.034DOI Listing
April 2018

Residues Comprising the Enhanced Aromatic Sequon Influence Protein N-Glycosylation Efficiency.

J Am Chem Soc 2017 09 6;139(37):12947-12955. Epub 2017 Sep 6.

Genomics Research Center Academia Sinica , Taipei 115, Taiwan.

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http://dx.doi.org/10.1021/jacs.7b03868DOI Listing
September 2017

An Effective Bacterial Fucosidase for Glycoprotein Remodeling.

ACS Chem Biol 2017 01 18;12(1):63-72. Epub 2016 Nov 18.

Genomics Research Center, Academia Sinica , No. 128, Section 2, Academia Road, Taipei 115, Taiwan.

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http://dx.doi.org/10.1021/acschembio.6b00821DOI Listing
January 2017

An Automatic Quality Control Pipeline for High-Throughput Screening Hit Identification.

J Biomol Screen 2016 Sep 16;21(8):832-41. Epub 2016 Jun 16.

Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA

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http://dx.doi.org/10.1177/1087057116654274DOI Listing
September 2016

Structural Investigation of Park's Nucleotide on Bacterial Translocase MraY: Discovery of Unexpected MraY Inhibitors.

Sci Rep 2016 08 17;6:31579. Epub 2016 Aug 17.

Genomics Research Center, Academia Sinica, No. 128 Academia Road, Section 2, Nankang District, Taipei, 11529, Taiwan.

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http://dx.doi.org/10.1038/srep31579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987650PMC
August 2016

Glycosylation-dependent interaction between CD69 and S100A8/S100A9 complex is required for regulatory T-cell differentiation.

FASEB J 2015 Dec 21;29(12):5006-17. Epub 2015 Aug 21.

*Institute of Biochemical Sciences, College of Life Science, National Taiwan University, Taipei, Taiwan; and Institute of Biological Chemistry and Genomics Research Center, Academia Sinica, Taipei, Taiwan

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http://dx.doi.org/10.1096/fj.15-273987DOI Listing
December 2015

Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase.

Biochemistry 2013 Dec 26;52(51):9375-84. Epub 2013 Nov 26.

Department of Microbiology and Immunology and ‡Department of Pharmacology, Weill Cornell Medical College , New York, New York 10065, United States.

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http://dx.doi.org/10.1021/bi401077fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894633PMC
December 2013

In vitro evaluation of novel inhibitors against the NS2B-NS3 protease of dengue fever virus type 4.

Molecules 2013 Dec 13;18(12):15600-12. Epub 2013 Dec 13.

Department of Biotechnology and Bioengineering, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 500-757, Korea.

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http://dx.doi.org/10.3390/molecules181215600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269914PMC
December 2013

From natural product-inspired pyrrolidine scaffolds to the development of new human Golgi α-mannosidase II inhibitors.

Chem Asian J 2013 Nov 13;8(11):2600-4. Epub 2013 Aug 13.

Genomics Research Center, Academia Sinica, 128 Academia Road, Sec. 2, Taipei 115 (Taiwan).

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http://dx.doi.org/10.1002/asia.201300680DOI Listing
November 2013

HotLig: a molecular surface-directed approach to scoring protein-ligand interactions.

J Chem Inf Model 2013 Aug 1;53(8):2181-95. Epub 2013 Aug 1.

Institute of Cellular and Organismic Biology, 128 Academia Road, Section 2, Nankang, Taipei 115, Taiwan.

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http://dx.doi.org/10.1021/ci400302dDOI Listing
August 2013

Engineering transaldolase in Pichia stipitis to improve bioethanol production.

ACS Chem Biol 2012 Mar 22;7(3):481-6. Epub 2011 Dec 22.

Genomics Research Center, Academia Sinica, Taipei, Taiwan.

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http://dx.doi.org/10.1021/cb200396bDOI Listing
March 2012

E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors.

Proc Natl Acad Sci U S A 2011 Oct 19;108(40):16515-20. Epub 2011 Sep 19.

Institute of Biological Chemistry and Genomics Research Center, Academia Sinica, Taipei 115, Taiwan.

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http://dx.doi.org/10.1073/pnas.1113107108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189076PMC
October 2011

High-throughput identification of antibacterials against methicillin-resistant Staphylococcus aureus (MRSA) and the transglycosylase.

Bioorg Med Chem 2010 Dec 21;18(24):8512-29. Epub 2010 Oct 21.

Genomics Research Center, Academia Sinica, 128 Sec 2 Academia Road, Nankang, Taipei 115, Taiwan. Genomics Research Center, Academia Sinica, 128 Sec 2 Academia Road, Nankang, Taipei 115, Taiwan.

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http://dx.doi.org/10.1016/j.bmc.2010.10.036DOI Listing
December 2010

HA-pseudotyped retroviral vectors for influenza antagonist screening.

J Biomol Screen 2009 Mar 11;14(3):294-302. Epub 2009 Feb 11.

Genomics Research Center, Academia Sinica, Taipei, Taiwan, Republic of China.

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http://dx.doi.org/10.1177/1087057108330786DOI Listing
March 2009

The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif.

Nat Struct Mol Biol 2008 Apr 12;15(4):419-21. Epub 2008 Feb 12.

Department of Chemistry, Ohio State University, 100 West 18th Ave., Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1038/nsmb.1400DOI Listing
April 2008

Synthesis and biological evaluation of substituted 6-alkynyl-4-anilinoquinazoline derivatives as potent EGFR inhibitors.

Bioorg Med Chem Lett 2007 Nov 28;17(22):6373-7. Epub 2007 Aug 28.

Development Center for Biotechnology, 102 Lane 169 Kang Ning Street, Xi Zhi, Taipei, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.bmcl.2007.08.061DOI Listing
November 2007

Grid-enabled high-throughput in silico screening against influenza A neuraminidase.

IEEE Trans Nanobioscience 2006 Dec;5(4):288-95

Academia Sinica, Taipei 115, Taiwan, ROC.

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December 2006

Discovery of different types of inhibition between the human and thermotoga maritima alpha-fucosidases by fuconojirimycin-based derivatives.

Biochemistry 2006 May;45(18):5695-702

Institute of Biological Chemistry and Genomics Research Center, Academia Sinica, No. 128, Academia Road Section 2, Nan-Kang, Taipei 11529, Taiwan.

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http://dx.doi.org/10.1021/bi052559nDOI Listing
May 2006

Stable benzotriazole esters as mechanism-based inactivators of the severe acute respiratory syndrome 3CL protease.

Chem Biol 2006 Mar;13(3):261-8

The Genomics Research Center and Institute of Biological Chemistry, Academia Sinica No. 128, Academia Road Section 2, Nan-Kang, Taipei, 115, Taiwan.

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http://linkinghub.elsevier.com/retrieve/pii/S107455210600007
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http://dx.doi.org/10.1016/j.chembiol.2005.12.008DOI Listing
March 2006

Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis.

Chembiochem 2006 Jan;7(1):165-73

The Genomics Research Center and Institute of Biomedical Sciences, Academia Sinica, No. 128, Academia Road Sec. 2, Nankang District, Taipei, 11529, Taiwan.

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http://dx.doi.org/10.1002/cbic.200500321DOI Listing
January 2006

Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors.

Bioorg Med Chem Lett 2005 Jun;15(12):3058-62

Development Center for Biotechnology, 102, Lane 169, Kang Ning St., Xi Zhi 221, Taipei, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.bmcl.2005.04.027DOI Listing
June 2005