Publications by authors named "Ying Swan Ho"

19Publications

Maternal factor NELFA drives a 2C-like state in mouse embryonic stem cells.

Nat Cell Biol 2020 02 13;22(2):175-186. Epub 2020 Jan 13.

Chromatin Dynamics and Disease Epigenetics Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

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http://dx.doi.org/10.1038/s41556-019-0453-8DOI Listing
February 2020

von Hippel-Lindau Protein Maintains Metabolic Balance to Regulate the Survival of Naive B Lymphocytes.

iScience 2019 Jul 4;17:379-392. Epub 2019 Jul 4.

Bioprocessing Technology Institute, Agency for Science, Technology and Research, 20 Biopolis Way, #06-01 Centros, Singapore 138668, Singapore; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117559, Singapore; Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117559, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660606PMC
July 2019

Multi-omics profiling of CHO parental hosts reveals cell line-specific variations in bioprocessing traits.

Biotechnol Bioeng 2019 09 20;116(9):2117-2129. Epub 2019 May 20.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore.

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http://dx.doi.org/10.1002/bit.27014DOI Listing
September 2019

An LC-MS-based lipidomics pre-processing framework underpins rapid hypothesis generation towards CHO systems biotechnology.

Metabolomics 2018 07 9;14(7):98. Epub 2018 Jul 9.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, Singapore, 138668, Singapore.

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http://dx.doi.org/10.1007/s11306-018-1394-0DOI Listing
July 2018

MMSET I acts as an oncoprotein and regulates GLO1 expression in t(4;14) multiple myeloma cells.

Leukemia 2019 03 23;33(3):739-748. Epub 2018 Nov 23.

Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.

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http://dx.doi.org/10.1038/s41375-018-0300-0DOI Listing
March 2019

Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR-Cas9 Activation.

Chembiochem 2018 May 25. Epub 2018 May 25.

Metabolic Engineering Research Laboratory (MERL), Science and Engineering Institutes, Agency for Science, Technology, and Research (A*STAR), 31 Biopolis Way, Nanos #01-01, Singapore, 138669, Singapore.

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http://doi.wiley.com/10.1002/cbic.201800266
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http://dx.doi.org/10.1002/cbic.201800266DOI Listing
May 2018

Excessive interferon-α signaling in autoimmunity alters glycosphingolipid processing in B cells.

J Autoimmun 2018 05 27;89:53-62. Epub 2017 Nov 27.

Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore 138668, Singapore; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 11799, Singapore; Department of Microbiology, and Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore; Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08968411173060
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http://dx.doi.org/10.1016/j.jaut.2017.11.004DOI Listing
May 2018

Mammalian Systems Biotechnology Reveals Global Cellular Adaptations in a Recombinant CHO Cell Line.

Cell Syst 2017 05;4(5):530-542.e6

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A(∗)STAR), 20 Biopolis Way, #06-01 Centros, Singapore 138668, Singapore; Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117576, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2017.04.009DOI Listing
May 2017

Evaluation and use of disaccharides as energy source in protein-free mammalian cell cultures.

Sci Rep 2017 03 30;7:45216. Epub 2017 Mar 30.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore.

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http://www.nature.com/articles/srep45216
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http://dx.doi.org/10.1038/srep45216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372174PMC
March 2017

LC-MS-based metabolic characterization of high monoclonal antibody-producing Chinese hamster ovary cells.

Biotechnol Bioeng 2012 Dec 4;109(12):3103-11. Epub 2012 Jul 4.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore 138668, Singapore.

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http://doi.wiley.com/10.1002/bit.24580
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http://dx.doi.org/10.1002/bit.24580DOI Listing
December 2012

Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture.

Biotechnol Bioeng 2012 Jun 31;109(6):1415-29. Epub 2012 Jan 31.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, Centros, Singapore 138668, Singapore.

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http://doi.wiley.com/10.1002/bit.24445
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http://dx.doi.org/10.1002/bit.24445DOI Listing
June 2012

Metabolomics-based identification of apoptosis-inducing metabolites in recombinant fed-batch CHO culture media.

J Biotechnol 2011 Jan 16;151(2):218-24. Epub 2010 Dec 16.

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), 20 Biopolis Way, #06-01, Singapore 138668, Singapore. william

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http://dx.doi.org/10.1016/j.jbiotec.2010.12.010DOI Listing
January 2011

Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: overexpression of malate dehydrogenase II.

J Biotechnol 2010 May 2;147(2):116-21. Epub 2010 Apr 2.

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), 20 Biopolis Way, #06-01 Centros, Singapore 138668, Singapore.

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http://dx.doi.org/10.1016/j.jbiotec.2010.03.018DOI Listing
May 2010

Metabolomics profiling of extracellular metabolites in recombinant Chinese Hamster Ovary fed-batch culture.

Rapid Commun Mass Spectrom 2009 Dec;23(23):3763-71

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), 20 Biopolis Way, Centros #06-01, Singapore 138668.

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http://doi.wiley.com/10.1002/rcm.4328
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http://dx.doi.org/10.1002/rcm.4328DOI Listing
December 2009