Yin Gu

Yin Gu

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Yin Gu

Yin Gu

Publications by authors named "Yin Gu"

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A Fully Integrated In Vitro Diagnostic Microsystem for Pathogen Detection Developed Using a "3D Extensible" Microfluidic Design Paradigm.

Micromachines (Basel) 2019 Dec 12;10(12). Epub 2019 Dec 12.

Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.3390/mi10120873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953088PMC
December 2019

How Lifestyle Factors Affect Cognitive and Executive Function and the Ability to Learn in Children.

Nutrients 2019 Aug 20;11(8). Epub 2019 Aug 20.

Department of Kinesiology, Curry School of Education and Human Development, University of Virginia, Charlottesville, VA 22903, USA.

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http://dx.doi.org/10.3390/nu11081953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723730PMC
August 2019

Modular-Based Integrated Microsystem with Multiple Sample Preparation Modules for Automated Forensic DNA Typing from Reference to Challenging Samples.

Anal Chem 2019 Jun 14;91(11):7435-7443. Epub 2019 May 14.

Department of Biomedical Engineering, School of Medicine, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases , Tsinghua University , Beijing , 100084 , China.

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http://dx.doi.org/10.1021/acs.analchem.9b01560DOI Listing
June 2019

Multiplex sample-to-answer detection of bacteria using a pipette-actuated capillary array comb with integrated DNA extraction, isothermal amplification, and smartphone detection.

Lab Chip 2018 09;18(18):2854-2864

Department of Biomedical Engineering, School of Medicine, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University, Beijing, 100084, China.

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http://dx.doi.org/10.1039/c8lc00543eDOI Listing
September 2018

Integrated Graphene Oxide Purification-Lateral Flow Test Strips (iGOP-LFTS) for Direct Detection of PCR Products with Enhanced Sensitivity and Specificity.

Anal Chem 2017 11 7;89(22):12137-12144. Epub 2017 Nov 7.

Department of Biomedical Engineering, School of Medicine, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University , Beijing, 100084, China.

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http://pubs.acs.org/doi/10.1021/acs.analchem.7b02769
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http://dx.doi.org/10.1021/acs.analchem.7b02769DOI Listing
November 2017

Intravenous vs Oral Acetaminophen as an Adjunct to Multimodal Analgesia After Total Knee Arthroplasty: A Prospective, Randomized, Double-Blind Clinical Trial.

J Arthroplasty 2017 10 18;32(10):3029-3033. Epub 2017 May 18.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.arth.2017.05.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605416PMC
October 2017

Chitosan-Modified Filter Paper for Nucleic Acid Extraction and "in Situ PCR" on a Thermoplastic Microchip.

Anal Chem 2017 03 8;89(6):3568-3575. Epub 2017 Mar 8.

Department of Biomedical Engineering, School of Medicine, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University , Beijing 100084, China.

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http://dx.doi.org/10.1021/acs.analchem.6b04882DOI Listing
March 2017

Association of gene polymorphisms of FV, FII, MTHFR, SERPINE1, CTLA4, IL10, and TNFalpha with pre-eclampsia in Chinese women.

Inflamm Res 2016 Sep 27;65(9):717-24. Epub 2016 May 27.

Department of Obstetrics and Gynecology, Maternal and Children's Hospital of Shenzhen City, Southern Medical University, Shenzhen, 518000, China.

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http://dx.doi.org/10.1007/s00011-016-0953-yDOI Listing
September 2016

Anesthesia management for cesarean section 10 years after heart transplantation: a case report.

Springerplus 2016 7;5(1):993. Epub 2016 Jul 7.

Department of Anesthesiology, Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, 518028 Guangdong China.

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http://dx.doi.org/10.1186/s40064-016-2701-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937040PMC
July 2016

Survival benefit of traditional Chinese herbal medicine (a herbal formula for invigorating spleen) for patients with advanced gastric cancer.

Integr Cancer Ther 2013 Sep 9;12(5):414-22. Epub 2012 Jul 9.

Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

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http://dx.doi.org/10.1177/1534735412450512DOI Listing
September 2013

Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors.

Bioorg Med Chem Lett 2010 Jul 25;20(14):4060-4. Epub 2010 May 25.

Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2010.05.086DOI Listing
July 2010

Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements.

Bioorg Med Chem Lett 2009 Nov 10;19(21):6131-4. Epub 2009 Sep 10.

Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2009.09.014DOI Listing
November 2009

Pyrazole-based arylalkyne cathepsin S inhibitors. Part II: optimization of cellular potency.

Bioorg Med Chem Lett 2009 Nov 10;19(21):6135-9. Epub 2009 Sep 10.

Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2009.09.013DOI Listing
November 2009

Pyrazole-based cathepsin S inhibitors with improved cellular potency.

Bioorg Med Chem Lett 2007 Oct 22;17(20):5525-8. Epub 2007 Aug 22.

Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2007.08.038DOI Listing
October 2007

Anti-inflammatory activity in vitro and in vivo of the protein farnesyltransferase inhibitor tipifarnib.

J Pharmacol Exp Ther 2006 Apr 13;317(1):53-60. Epub 2005 Dec 13.

Alza/Johnson & Johnson Pharmaceutical Research & Development-La Jolla, San Diego, California, USA.

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http://dx.doi.org/10.1124/jpet.105.095976DOI Listing
April 2006

The SAR of 4-substituted (6,6-bicyclic) piperidine cathepsin S inhibitors.

Bioorg Med Chem Lett 2006 Apr 3;16(8):2209-12. Epub 2006 Feb 3.

Johnson and Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2006.01.038DOI Listing
April 2006

Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors.

Bioorg Med Chem Lett 2005 Mar;15(6):1687-91

Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2005.01.045DOI Listing
March 2005

Identification of a potent and selective noncovalent cathepsin S inhibitor.

J Pharmacol Exp Ther 2004 Jan 17;308(1):268-76. Epub 2003 Oct 17.

Johnson & Johnson Pharmaceutical Research & Development L.L.C., San Diego, California, USA.

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http://dx.doi.org/10.1124/jpet.103.056879DOI Listing
January 2004