Publications by authors named "Yilu He"

5 Publications

  • Page 1 of 1

Spontaneous bleeding from an unusual renal mass: A case of gestational choriocarcinoma related to previous pregnancy over a decade earlier.

Urol Case Rep 2021 Jul 17;37:101614. Epub 2021 Mar 17.

Nepean Urology Research Group, Nepean Hospital, Kingswood, NSW, Australia.

Gestational choriocarcinoma is an uncommon trophoblastic malignancy, occurring in females after pregnancy, which is rarely encountered by urologists. It can be rapidly progressive, however metastases to other organs can occur after a prolonged latency period. We describe a rare case of solitary metastatic gestational choriocarcinoma presenting with spontaneous bleeding from a renal mass, over a decade after the associated pregnancy with a presumed sub-clinical primary tumour. This case demonstrates the importance of recognising gestational choriocarcinoma as a potential differential diagnosis of spontaneous bleeding renal mass in females of child-bearing age as a urologist given the often-aggressive nature of the disease.
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http://dx.doi.org/10.1016/j.eucr.2021.101614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020421PMC
July 2021

A Systematic Review and Meta-Analysis of the Significance of Body Mass Index on Kidney Cancer Outcomes.

J Urol 2021 02 18;205(2):346-355. Epub 2020 Sep 18.

Department of Urology, Westmead Hospital, Westmead, New South Wales, Australia.

Purpose: Obesity is a well-known risk factor for kidney cancer incidence. However, a number of studies have demonstrated more favorable kidney cancer prognosis in patients with elevated body mass index conferring a survival advantage, termed the "obesity paradox." We aimed to evaluate the association between body mass index and kidney cancer outcomes (progression-free survival, cancer specific survival and overall survival).

Materials And Methods: A computerized systematic search of Medline®, Embase®, ProQuest®, PubMed® and Google Scholar™ for literature published in English was performed between its inception and December 2018, and Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were used for reporting.

Results: Overall, 34 publications comprising a total of 50,717 patients were included in the analysis. The majority assessed the association between body mass index and cancer specific survival. Overweight and obese patients were associated with improved cancer specific survival compared to patients with normal body mass index (HR 0.85, 95% CI 0.79-0.93). A similar trend was demonstrated for progression-free survival (HR 0.68, 95% CI 0.59-0.78) and overall survival (HR 0.66, 95% CI 0.55-0.79). On the contrary, the underweight group was associated with inferior cancer specific survival (HR 2.16, 95% CI 1.15-4.04). Main drawbacks limiting the interpretation were the retrospective design in the majority of studies, heterogeneity in study population, body mass index classification and covariates in multivariate analysis.

Conclusions: This is the largest systematic review evaluating the potential phenomenon of the obesity paradox in kidney cancer outcomes. It demonstrated a favorable effect of body mass index on kidney cancer outcomes. However, due to significant heterogeneity of studies, multicenter prospective studies and further research on the fundamental biological mechanisms are warranted to confirm the significance of body mass index on kidney cancer prognosis.
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http://dx.doi.org/10.1097/JU.0000000000001377DOI Listing
February 2021

Case of intermittent testicular torsion and de-torsion captured on scrotal ultrasound.

ANZ J Surg 2021 03 6;91(3):E135-E136. Epub 2020 Aug 6.

Nepean Urology Research Group, Nepean Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/ans.16161DOI Listing
March 2021

Metachronous ureteral metastasis of clear cell renal cell carcinoma in a duplex collecting system 1 year after nephrectomy.

Urol Case Rep 2020 Sep 16;32:101214. Epub 2020 Apr 16.

Nepean Urology Research Group, Nepean Hospital, PO Box 63, Penrith, NSW, 2751, Australia.

While renal cell carcinoma is known to metastasise in an unpredictable pattern, even after resection of a primary tumour, delayed ureteric metastasis is a very rarely reported phenomenon. In this case report, we describe a case of ipsilateral metachronous ureteric metastasis in a patient with a complete duplex collecting system. This case demonstrates some useful strategies in the diagnosis and treatment of renal cell carcinoma in this context. To our knowledge, this is the first case report of delayed ureteric metastasis of a renal clear cell carcinoma in a patient with a duplex collecting system.
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http://dx.doi.org/10.1016/j.eucr.2020.101214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184155PMC
September 2020

A Rare Case of Extensive Unilateral Ureteritis Cystica.

Urology 2020 Apr 22;138:e3-e4. Epub 2020 Jan 22.

Department of Urology, Canberra Hospital, Garran, Canberra, Australia.

Ureteritis cystica is rare, benign entity that associates with chronic urothelial irritation such as recurrent urinary tract infection or nephrolithiasis. It is often diagnosed incidentally on routine imaging or ureteroscopy in asymptomatic individuals. In this case report, we present the retrograde pyelogram and ureteroscopy images of a rare case of extensive unilateral ureteritis cystica in a 78-year-old female presenting for elective stone surgery.
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http://dx.doi.org/10.1016/j.urology.2020.01.017DOI Listing
April 2020