Publications by authors named "Yihai Cao"

100Publications

In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment.

Proc Natl Acad Sci U S A 2020 Nov 2;117(46):28667-28677. Epub 2020 Nov 2.

Center for Nanomedicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.2016268117DOI Listing
November 2020

A materials-science perspective on tackling COVID-19.

Nat Rev Mater 2020 Oct 14:1-14. Epub 2020 Oct 14.

Center for Nanomedicine and Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA USA.

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http://dx.doi.org/10.1038/s41578-020-00247-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556605PMC
October 2020

Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis.

Cell Rep 2020 Aug;32(5):107990

State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education) and Department of Physiology and Pathophysiology, Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University, Tianjin 300070, China; Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107990DOI Listing
August 2020

Mitochondrial DNA: A New Predictor of Diabetic Kidney Disease.

Int J Endocrinol 2020 15;2020:3650937. Epub 2020 Jul 15.

Department of Endocrinology, The Affiliated Hospital of Medical College of Qingdao University, Qingdao 266003, China.

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http://dx.doi.org/10.1155/2020/3650937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378596PMC
July 2020

NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma.

Mol Neurodegener 2020 04 15;15(1):26. Epub 2020 Apr 15.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.

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http://dx.doi.org/10.1186/s13024-020-00372-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161290PMC
April 2020

Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation.

Nat Commun 2020 03 5;11(1):1211. Epub 2020 Mar 5.

Department of Medical Oncology and cancer institute, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, 201203, Shanghai, China.

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http://dx.doi.org/10.1038/s41467-020-14869-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058049PMC
March 2020

Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload.

Proc Natl Acad Sci U S A 2019 09 5;116(39):19635-19645. Epub 2019 Sep 5.

Zhejiang Provincial Key Laboratory of Silkworm Bioreactor and Biomedicine, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, 310018 Hangzhou, China;

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http://dx.doi.org/10.1073/pnas.1908998116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765257PMC
September 2019

Endothelial life discontinues without Erk.

Authors:
Yihai Cao

J Exp Med 2019 08 18;216(8):1730-1732. Epub 2019 Jul 18.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden

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http://www.jem.org/lookup/doi/10.1084/jem.20191048
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http://dx.doi.org/10.1084/jem.20191048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683985PMC
August 2019

Adipocyte and lipid metabolism in cancer drug resistance.

Authors:
Yihai Cao

J Clin Invest 2019 07 2;129(8):3006-3017. Epub 2019 Jul 2.

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http://dx.doi.org/10.1172/JCI127201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668696PMC
July 2019

Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma.

Autophagy 2020 01 9;16(1):106-122. Epub 2019 Apr 9.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, P.R. China.

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http://dx.doi.org/10.1080/15548627.2019.1598752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984601PMC
January 2020

Synchronized tissue-scale vasculogenesis and ubiquitous lateral sprouting underlie the unique architecture of the choriocapillaris.

Dev Biol 2020 01 21;457(2):206-214. Epub 2019 Feb 21.

Division of Cardiovascular Medicine, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2019.02.002DOI Listing
January 2020

VEGF-B is a potent antioxidant.

Proc Natl Acad Sci U S A 2018 10 24;115(41):10351-10356. Epub 2018 Sep 24.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong, China;

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http://dx.doi.org/10.1073/pnas.1801379115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187152PMC
October 2018

Obesity Protects Cancer from Drugs Targeting Blood Vessels.

Authors:
Yihai Cao

Cell Metab 2018 06;27(6):1163-1165

Department of Microbiology, Tumor, and Cell Biology, Karolinska Institutet, 171 77 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.05.014DOI Listing
June 2018

Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance.

Cell Metab 2018 Jul 31;28(1):104-117.e5. Epub 2018 May 31.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm 171 77, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.05.005DOI Listing
July 2018

A novel mechanism of the M1-M2 methionine adenosyltransferase switch-mediated hepatocellular carcinoma metastasis.

Mol Carcinog 2018 09 27;57(9):1201-1212. Epub 2018 May 27.

Department of Interventional Oncology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, P.R. China.

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http://dx.doi.org/10.1002/mc.22836DOI Listing
September 2018

Ablation of endothelial VEGFR1 improves metabolic dysfunction by inducing adipose tissue browning.

J Exp Med 2018 02 5;215(2):611-626. Epub 2018 Jan 5.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden

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http://dx.doi.org/10.1084/jem.20171012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789413PMC
February 2018

Critical role of caveolin-1 in ocular neovascularization and multitargeted antiangiogenic effects of cavtratin via JNK.

Proc Natl Acad Sci U S A 2017 10 18;114(40):10737-10742. Epub 2017 Sep 18.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, People's Republic of China;

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http://dx.doi.org/10.1073/pnas.1706394114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635880PMC
October 2017

MicroRNA-26a and -26b inhibit lens fibrosis and cataract by negatively regulating Jagged-1/Notch signaling pathway.

Cell Death Differ 2017 08 16;24(8):1431-1442. Epub 2017 Jun 16.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54S Xianlie Road, Guangzhou 510060, People's Republic of China.

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http://dx.doi.org/10.1038/cdd.2016.152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520447PMC
August 2017

Maintenance of antiangiogenic and antitumor effects by orally active low-dose capecitabine for long-term cancer therapy.

Proc Natl Acad Sci U S A 2017 06 12;114(26):E5226-E5235. Epub 2017 Jun 12.

Central Research Laboratory, The Affiliated Hospital of Qingdao University, Qingdao 266071, China;

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http://dx.doi.org/10.1073/pnas.1705066114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495268PMC
June 2017

A Zebrafish Model Discovers a Novel Mechanism of Stromal Fibroblast-Mediated Cancer Metastasis.

Clin Cancer Res 2017 Aug 18;23(16):4769-4779. Epub 2017 Apr 18.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-0101DOI Listing
August 2017

Switching harmful visceral fat to beneficial energy combustion improves metabolic dysfunctions.

JCI Insight 2017 02 23;2(4):e89044. Epub 2017 Feb 23.

The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Shandong University Qilu Hospital, Jinan, Shandong, China.

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http://dx.doi.org/10.1172/jci.insight.89044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313060PMC
February 2017

Residential Proximity to Major Roadways and Risk of Type 2 Diabetes Mellitus: A Meta-Analysis.

Int J Environ Res Public Health 2016 12 22;14(1). Epub 2016 Dec 22.

Department of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao 266003, China.

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http://dx.doi.org/10.3390/ijerph14010003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295254PMC
December 2016

Co-option of pre-existing vascular beds in adipose tissue controls tumor growth rates and angiogenesis.

Oncotarget 2016 Jun;7(25):38282-38291

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.18632/oncotarget.9436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122389PMC
June 2016

Pericyte-fibroblast transition promotes tumor growth and metastasis.

Proc Natl Acad Sci U S A 2016 09 7;113(38):E5618-27. Epub 2016 Sep 7.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden; Key Laboratory of International Collaborations, Second People's Hospital of Shenzhen, First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE1 7RH, United Kingdom

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035870PMC
http://dx.doi.org/10.1073/pnas.1608384113DOI Listing
September 2016

Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism.

Cancer Res 2016 10 25;76(19):5634-5646. Epub 2016 Jul 25.

Department of Biosciences and Nutrition, Novum, Karolinska Institutet, Huddinge, Sweden.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2910DOI Listing
October 2016

Endocrine vasculatures are preferable targets of an antitumor ineffective low dose of anti-VEGF therapy.

Proc Natl Acad Sci U S A 2016 Apr 28;113(15):4158-63. Epub 2016 Mar 28.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden; Department of Cardiovascular Sciences, University of Leicester and National Institute of Health Research Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, United Kingdom; Department of Medicine, The Second Hospital of Wuxi, Wuxi, Jiangsu 214002, People's Republic of China; Department of Medicine and Health Sciences, Linköping University, 581 83 Linköping, Sweden

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http://dx.doi.org/10.1073/pnas.1601649113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839458PMC
April 2016

MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis.

Nat Commun 2016 Mar 1;7:10824. Epub 2016 Mar 1.

Shenzhen Institute of Research and Innovation, University of Hong Kong, Shenzhen 518057, China.

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http://dx.doi.org/10.1038/ncomms10824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773521PMC
March 2016

Future options of anti-angiogenic cancer therapy.

Authors:
Yihai Cao

Chin J Cancer 2016 Feb 15;35:21. Epub 2016 Feb 15.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s40880-016-0084-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753668PMC
February 2016

Resveratrol analogue 4,4'-dihydroxy-trans-stilbene potently inhibits cancer invasion and metastasis.

Sci Rep 2016 Feb 1;6:19973. Epub 2016 Feb 1.

Department of Molecular Medicine, Immunology and General Pathology Unit, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1038/srep19973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734289PMC
February 2016

PlGF-induced VEGFR1-dependent vascular remodeling determines opposing antitumor effects and drug resistance to Dll4-Notch inhibitors.

Sci Adv 2015 Apr 10;1(3):e1400244. Epub 2015 Apr 10.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden. ; Department of Medicine and Health Sciences, Linköping University, 581 83 Linköping, Sweden. ; Department of Cardiovascular Sciences, University of Leicester, and NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK.

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http://dx.doi.org/10.1126/sciadv.1400244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640632PMC
April 2015

Environmental changes in oxygen tension reveal ROS-dependent neurogenesis and regeneration in the adult newt brain.

Elife 2015 Oct 20;4. Epub 2015 Oct 20.

Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.7554/eLife.08422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635398PMC
October 2015

VEGF-B-Neuropilin-1 signaling is spatiotemporally indispensable for vascular and neuronal development in zebrafish.

Proc Natl Acad Sci U S A 2015 Nov 19;112(44):E5944-53. Epub 2015 Oct 19.

Department of Microbiology, Tumor, and Cell Biology, Karolinska Institutet, 171 77 Stockholm, Sweden; Unit of Cardiovascular Medicine, Department of Medical and Health Sciences, Linköping University, 581 83 Linköping, Sweden; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester, Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, United Kingdom

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http://www.pnas.org/lookup/doi/10.1073/pnas.1510245112
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http://dx.doi.org/10.1073/pnas.1510245112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640767PMC
November 2015

Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model.

Sci Rep 2015 Jul 14;5:10351. Epub 2015 Jul 14.

1] Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden [2] Department of Medicine and Health Sciences, Linköping University, 581 83. Linköping, Sweden [3] Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, LE3 9QP, UK.

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http://dx.doi.org/10.1038/srep10351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501005PMC
July 2015

VEGF-B promotes cancer metastasis through a VEGF-A-independent mechanism and serves as a marker of poor prognosis for cancer patients.

Proc Natl Acad Sci U S A 2015 Jun 19;112(22):E2900-9. Epub 2015 May 19.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden; Department of Medicine and Health Sciences, Linköping University, 581 83 Linköping, Sweden; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, United Kingdom; National Institute for Health Research Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, United Kingdom

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http://dx.doi.org/10.1073/pnas.1503500112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460438PMC
June 2015

Collaborative effects between the TNFα-TNFR1-macrophage axis and the VEGF-C-VEGFR3 signaling in lymphangiogenesis and metastasis.

Oncoimmunology 2015 Mar 22;4(3):e989777. Epub 2015 Jan 22.

Department of Microbiology; Tumor and Cell Biology; Karolinska Institute ; Stockholm, Sweden ; Department of Medicine and Health Sciences; Linköping University ; Linköping, Sweden ; Department of Cardiovascular Sciences; University of Leicester and NIHR Leicester Cardiovascular Biomedical Research Unit; Glenfield Hospital ; Leicester, UK.

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http://dx.doi.org/10.4161/2162402X.2014.989777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404838PMC
March 2015

CCL2 and CCL5 Are Novel Therapeutic Targets for Estrogen-Dependent Breast Cancer.

Clin Cancer Res 2015 Aug 21;21(16):3794-805. Epub 2015 Apr 21.

Department of Oncology and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0204DOI Listing
August 2015

Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development.

Cancer Res 2015 Jan 9;75(2):306-15. Epub 2014 Dec 9.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden. Department of Medicine and Health Sciences, Linköping University, Linköping, Sweden. Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, United Kingdom.

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http://cancerres.aacrjournals.org/content/early/2015/01/07/0
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http://cancerres.aacrjournals.org/content/early/2014/12/09/0
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-14-2819DOI Listing
January 2015

VEGFR2-mediated vascular dilation as a mechanism of VEGF-induced anemia and bone marrow cell mobilization.

Cell Rep 2014 Oct 9;9(2):569-80. Epub 2014 Oct 9.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden; Department of Medicine and Health Sciences, Linköping University, 581 83 Linköping, Sweden; Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(14)00771-2.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471400771
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http://dx.doi.org/10.1016/j.celrep.2014.09.003DOI Listing
October 2014

Modulation of age-related insulin sensitivity by VEGF-dependent vascular plasticity in adipose tissues.

Proc Natl Acad Sci U S A 2014 Oct 30;111(41):14906-11. Epub 2014 Sep 30.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden; Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, United Kingdom; and Department of Medicine and Health Sciences, Linköping University, 581 83 Linköping, Sweden

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http://www.pnas.org/cgi/doi/10.1073/pnas.1415825111
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http://dx.doi.org/10.1073/pnas.1415825111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205611PMC
October 2014

Vasoprotective effect of PDGF-CC mediated by HMOX1 rescues retinal degeneration.

Proc Natl Acad Sci U S A 2014 Oct 29;111(41):14806-11. Epub 2014 Sep 29.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, People's Republic of China;

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http://dx.doi.org/10.1073/pnas.1404140111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205610PMC
October 2014

TNFR1 mediates TNF-α-induced tumour lymphangiogenesis and metastasis by modulating VEGF-C-VEGFR3 signalling.

Nat Commun 2014 Sep 17;5:4944. Epub 2014 Sep 17.

1] Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden [2] Department of Medicine and Health Sciences, Linköping University, 581 83 Linköping, Sweden [3] Department of Cardiovascular Sciences, Glenfield Hospital, University of Leicester, Leicester LE3 9QP, UK.

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http://www.nature.com/articles/ncomms5944
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http://dx.doi.org/10.1038/ncomms5944DOI Listing
September 2014

VEGF-targeted cancer therapeutics-paradoxical effects in endocrine organs.

Authors:
Yihai Cao

Nat Rev Endocrinol 2014 Sep 22;10(9):530-9. Epub 2014 Jul 22.

Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet, Nobels vag 16, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.1038/nrendo.2014.114DOI Listing
September 2014

Genome-wide profiling of AP-1-regulated transcription provides insights into the invasiveness of triple-negative breast cancer.

Cancer Res 2014 Jul 15;74(14):3983-94. Epub 2014 May 15.

Authors' Affiliations: Department of Biosciences and Nutrition, Novum, Karolinska Institute, Huddinge; Science for Life Laboratory, Karolinska Institute, Solna, Sweden;

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3396DOI Listing
July 2014

Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response.

Proc Natl Acad Sci U S A 2014 Feb 3;111(7):2560-5. Epub 2014 Feb 3.

Department of Cell and Molecular Biology and Microbiology and Tumor Biology Center, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.1320815111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932879PMC
February 2014

Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1.

Proc Natl Acad Sci U S A 2013 Dec 25;110(50):20057-62. Epub 2013 Nov 25.

Department of Medical Biochemistry and Biophysics, Department of Molecular Tumor and Cell Biology, and Institute of Environmental Medicine, Karolinska Institutet, 17177, Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.1313753110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864331PMC
December 2013

Angiogenesis as a therapeutic target for obesity and metabolic diseases.

Authors:
Yihai Cao

Chem Immunol Allergy 2014 17;99:170-9. Epub 2013 Oct 17.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1159/000353254DOI Listing
July 2014

Angiogenesis and vascular functions in modulation of obesity, adipose metabolism, and insulin sensitivity.

Authors:
Yihai Cao

Cell Metab 2013 Oct 12;18(4):478-89. Epub 2013 Sep 12.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden; Department of Medicine and Health Sciences, Linköping University, 581 85 Linköping, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2013.08.008DOI Listing
October 2013

Vascular endothelial growth factor-dependent spatiotemporal dual roles of placental growth factor in modulation of angiogenesis and tumor growth.

Proc Natl Acad Sci U S A 2013 Aug 5;110(34):13932-7. Epub 2013 Aug 5.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.1309629110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752238PMC
August 2013

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.

Science 2013 Jul;341(6141):84-7

Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1126/science.1233606DOI Listing
July 2013

Cold exposure promotes atherosclerotic plaque growth and instability via UCP1-dependent lipolysis.

Cell Metab 2013 Jul;18(1):118-29

The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong 250012, People's Republic of China.

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http://www.cell.com/cell-metabolism/pdf/S1550-4131(13)00247-
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http://linkinghub.elsevier.com/retrieve/pii/S155041311300247
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http://dx.doi.org/10.1016/j.cmet.2013.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701322PMC
July 2013

Anti-VEGF- and anti-VEGF receptor-induced vascular alteration in mouse healthy tissues.

Proc Natl Acad Sci U S A 2013 Jul 1;110(29):12018-23. Epub 2013 Jul 1.

Department of Microbiology, Karolinska Institute, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.1301331110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718173PMC
July 2013

Multifarious functions of PDGFs and PDGFRs in tumor growth and metastasis.

Authors:
Yihai Cao

Trends Mol Med 2013 Aug 15;19(8):460-73. Epub 2013 Jun 15.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.molmed.2013.05.002DOI Listing
August 2013

Clock controls angiogenesis.

Cell Cycle 2013 Feb 16;12(3):405-8. Epub 2013 Jan 16.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.4161/cc.23596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587440PMC
February 2013

Tumor cell-derived placental growth factor sensitizes antiangiogenic and antitumor effects of anti-VEGF drugs.

Proc Natl Acad Sci U S A 2013 Jan 24;110(2):654-9. Epub 2012 Dec 24.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.1209310110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545771PMC
January 2013

Erythropoietin in cancer: a dilemma in risk therapy.

Authors:
Yihai Cao

Trends Endocrinol Metab 2013 Apr 5;24(4):190-9. Epub 2012 Dec 5.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.tem.2012.10.007DOI Listing
April 2013

Collaborative interplay between FGF-2 and VEGF-C promotes lymphangiogenesis and metastasis.

Proc Natl Acad Sci U S A 2012 Sep 11;109(39):15894-9. Epub 2012 Sep 11.

Department of Microbiology, Tumor, and Cell Biology, Karolinska Institute, Stockholm, Sweden.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1208324109
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465417PMC
September 2012

Targeting filamin A reduces K-RAS-induced lung adenocarcinomas and endothelial response to tumor growth in mice.

Mol Cancer 2012 Aug 2;11:50. Epub 2012 Aug 2.

Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Sahlgrenska Academy, SE-405 30, Göteborg, Sweden.

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http://dx.doi.org/10.1186/1476-4598-11-50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441416PMC
August 2012

When MT1-MMP meets ADAMs.

Cell Cycle 2012 Aug 1;11(15):2793-8. Epub 2012 Aug 1.

Shenzhen Institute of Research and Innovation, The University of Hong Kong, Shenzhen, China.

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http://dx.doi.org/10.4161/cc.20949DOI Listing
August 2012

MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis.

Dev Cell 2012 Jun 24;22(6):1176-90. Epub 2012 May 24.

Shenzhen Institute of Research and Innovation, The University of Hong Kong, Shenzhen, China.

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http://dx.doi.org/10.1016/j.devcel.2012.04.014DOI Listing
June 2012

Cold-induced activation of brown adipose tissue and adipose angiogenesis in mice.

Nat Protoc 2012 Mar 1;7(3):606-15. Epub 2012 Mar 1.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1038/nprot.2012.013DOI Listing
March 2012

Forty-year journey of angiogenesis translational research.

Sci Transl Med 2011 Dec;3(114):114rv3

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1126/scitranslmed.3003149DOI Listing
December 2011

PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells.

Nat Med 2011 Dec 4;18(1):100-10. Epub 2011 Dec 4.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1038/nm.2575DOI Listing
December 2011

Antiangiogenic cancer therapy: why do mouse and human patients respond in a different way to the same drug?

Authors:
Yihai Cao

Int J Dev Biol 2011 ;55(4-5):557-62

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1387/ijdb.103236ycDOI Listing
November 2011

Zebrafish models to study hypoxia-induced pathological angiogenesis in malignant and nonmalignant diseases.

Birth Defects Res C Embryo Today 2011 Jun;93(2):182-93

Deparment of Microbiology, Tumor and Cell biology, Karolinska Institutet, Stockholm, Sweden.

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http://doi.wiley.com/10.1002/bdrc.20203
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June 2011

Mouse corneal lymphangiogenesis model.

Nat Protoc 2011 Jun 19;6(6):817-26. Epub 2011 May 19.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/nprot.2011.359DOI Listing
June 2011

Antiangiogenic agents significantly improve survival in tumor-bearing mice by increasing tolerance to chemotherapy-induced toxicity.

Proc Natl Acad Sci U S A 2011 Mar 18;108(10):4117-22. Epub 2011 Feb 18.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77 Stockholm, Sweden.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1016220108
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053963PMC
March 2011

It's hard to keep all things angiogenic in one JAR!

Vasc Cell 2011 Jan 18;3(1). Epub 2011 Jan 18.

Columbia University Medical Centre, Columbia New York, USA.

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http://dx.doi.org/10.1186/2045-824X-3-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039830PMC
January 2011

Hypoxia-induced metastasis model in embryonic zebrafish.

Nat Protoc 2010 Dec 4;5(12):1911-8. Epub 2010 Nov 4.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/nprot.2010.150DOI Listing
December 2010

Hypoxia-induced retinopathy model in adult zebrafish.

Nat Protoc 2010 Dec 4;5(12):1903-10. Epub 2010 Nov 4.

Institute of Medicine and Health, Linkoping University, Linkoping, Sweden.

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http://dx.doi.org/10.1038/nprot.2010.149DOI Listing
December 2010