Publications










High-throughput detection of clinically relevant mutations in archived tumor samples by multiplexed PCR and next-generation sequencing.
Clin Cancer Res 2014 Apr 26;20(8):2080-91. Epub 2014 Feb 26.
Authors' Affiliations: Departments of Oncology Biomarker Development, Bioinformatics, Structural Biology, and Pathology, Genentech, Inc.; Fluidigm Inc., South San Francisco, California; and Expression Analysis, Durham, North Carolina.

Evaluation and clinical analyses of downstream targets of the Akt inhibitor GDC-0068.
Clin Cancer Res 2013 Dec 18;19(24):6976-86. Epub 2013 Oct 18.
Authors' Affiliations: Oncology Biomarker Development, Portfolio Management and Operations, Translational Oncology, Biostatistics, and Exploratory Clinical Development, Genentech Inc., DNA Way, South San Francisco, California; Experimental Therapeutics, Molecular Pathology, Breast Cancer and Melanoma, Gastrointestinal and Endocrine Tumors Groups, and Medical Oncology Service, Vall d'Hebron Institute of Oncology, Barcelona; Department of Hematology and Medical Oncology, Institute of Health Research INCLIVA, University of Valencia, Valencia, Spain; and Human Oncology and Pathogenesis Program and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.





Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice.
Proc Natl Acad Sci U S A 2005 Jul 30;102(28):9884-9. Epub 2005 Jun 30.
Pacific Vascular Research Laboratory, Division of Vascular Surgery, Department of Surgery and Department of Anatomy, University of California-San Francisco, San Francisco, CA 94143, USA.



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