Yi-An Ko

Yi-An Ko

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Yi-An Ko

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Genomic Mismatch at Locus and Kidney Allograft Rejection.

N Engl J Med 2019 05;380(20):1918-1928

From the Department of Medicine, Division of Nephrology (N.J.S., Y.L., J.A.D., C.F., L.L., K.X., Y.-J.N., Y.D.N., J.Y.Z., R.S., O.B., D.B., N.O., F.O., S.G., K.M., J.W., S.M., J.R., D.J.C., J.B., A.G.G., K.K.), the Department of Surgery (L.E.R.), and the Department of Pathology and Cell Biology (E.-R.M.V., G.V., V.D.), Vagelos College of Physicians and Surgeons, and the Departments of Epidemiology (S.M.) and Biostatistics (I.I.-L.), Mailman School of Public Health, Columbia University, New York; Immunogenetics and Biology of Transplantation, Città della Salute e della Scienza, University Hospital of Turin, and Medical Genetics, Department of Medical Sciences, University of Turin, Turin (Z.D., S.D., A.A.), and the Division of Nephrology, Azienda Ospedaliera Spedali Civili of Brescia, Montichiari Hospital, University of Brescia, Brescia (F.S.) - all in Italy; the Department of Pathology, M.D. Anderson Cancer Center, Houston (F.Z.J.); the Division of Genetics and Genomics, Boston Children's Hospital, and the Department of Medical Oncology, Dana-Farber Cancer Institute, Boston (M.R.); the Department of Pediatrics, Division of Pediatric Nephrology, University of Michigan School of Medicine, Ann Arbor (C.E.G., M.G.S.); the Department of Medicine, Renal, Electrolyte, and Hypertension Division, University of Pennsylvania, Philadelphia (Y.-A.K., K.S.); the Division of Nephrology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey (Y.C.); the Nephrology Research Group, Queen's University of Belfast, Belfast, United Kingdom (A.E.C., A.P.M., A.J.M.); and the Department of Internal Medicine, Division of Nephrology (S.J.L.B., M.H.B.), and the Department of Epidemiology, Unit of Genetic Epidemiology and Bioinformatics (H.S.), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1056/NEJMoa1803731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589355PMC
May 2019

The Influence of Multidirectional Shear Stress on Plaque Progression and Composition Changes in Human Coronary Arteries.

EuroIntervention 2019 Mar 12. Epub 2019 Mar 12.

Department of Cardiology, Biomedical Engineering, Erasmus MC, Rotterdam, the Netherlands.

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http://dx.doi.org/10.4244/EIJ-D-18-00529DOI Listing
March 2019

Corrigendum to: "Urinary phthalate metabolite and bisphenol A associations with ultrasound and delivery indices of fetal growth" [Environment International 94 (2016) 531-537].

Environ Int 2019 01;122:416

Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2018.11.062DOI Listing
January 2019

Understanding preferences regarding consent for pragmatic trials in acute care.

Clin Trials 2018 12 3;15(6):567-578. Epub 2018 Oct 3.

2 Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

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http://journals.sagepub.com/doi/10.1177/1740774518801007
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http://dx.doi.org/10.1177/1740774518801007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218277PMC
December 2018

Oestrogen fuels the growth of endometrial hyperplastic lesions initiated by overactive Wnt/β-catenin signalling.

Carcinogenesis 2018 09;39(9):1105-1116

Gynaecology Oncology Group, School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales Australia.

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http://dx.doi.org/10.1093/carcin/bgy079DOI Listing
September 2018

Circulating Progenitor Cells and Racial Differences.

Circ Res 2018 Aug;123(4):467-476

From the Division of Cardiology, Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine (A.S.T., M.H., H.M.K., J.H.K., P.B.S., A.A., B.K., M.M.G., M.T., S.S.H., W.T.O., M.O., I.H., V.V., A.A.Q.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.31328
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http://dx.doi.org/10.1161/CIRCRESAHA.118.313282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202175PMC
August 2018

Extracellular matrix (ECM) activates β-catenin signaling in uterine fibroids.

Reproduction 2018 01 24;155(1):61-71. Epub 2017 Oct 24.

School of Biomedical Sciences and PharmacyUniversity of Newcastle, Callaghan, New South Wales, Australia

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http://dx.doi.org/10.1530/REP-17-0339DOI Listing
January 2018

Increasing hip and knee flexion during a drop-jump task reduces tibiofemoral shear and compressive forces: implications for ACL injury prevention training.

J Sports Sci 2017 Dec 23;35(24):2405-2411. Epub 2016 Dec 23.

d Division of Biokinesiology and Physical Therapy , University of Southern California , Los Angeles , CA , USA.

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https://www.tandfonline.com/doi/full/10.1080/02640414.2016.1
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http://dx.doi.org/10.1080/02640414.2016.1271138DOI Listing
December 2017

Association between oxidative stress and atrial fibrillation.

Heart Rhythm 2017 12 27;14(12):1849-1855. Epub 2017 Jul 27.

Division of Cardiology, Emory University School of Medicine, Emory Clinical Cardiovascular Research Institute, Atlanta, Georgia. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2017.07.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817893PMC
December 2017

Assessment of Commonly Used Frailty Markers for High- and Extreme-Risk Patients Undergoing Transcatheter Aortic Valve Replacement.

Ann Thorac Surg 2017 Dec 21;104(6):1939-1946. Epub 2017 Sep 21.

Structural Heart and Valve Center, Division of Cardiothoracic Surgery, Joseph B. Whitehead Department of Surgery, Emory University School of Medicine, Atlanta, Georgia. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2017.05.067DOI Listing
December 2017

Marital Status and Outcomes in Patients With Cardiovascular Disease.

J Am Heart Assoc 2017 Dec 20;6(12). Epub 2017 Dec 20.

Division of Cardiology, Department of Medicine, Emory Clinical Cardiovascular Research Institute Emory University School of Medicine, Atlanta, GA

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http://dx.doi.org/10.1161/JAHA.117.005890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778993PMC
December 2017

Cohort profile: the Emory Cardiovascular Biobank (EmCAB).

BMJ Open 2017 12 29;7(12):e018753. Epub 2017 Dec 29.

Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1136/bmjopen-2017-018753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778297PMC
December 2017

Human Kidney Tubule-Specific Gene Expression Based Dissection of Chronic Kidney Disease Traits.

EBioMedicine 2017 Oct 18;24:267-276. Epub 2017 Sep 18.

Department Genetics and Medicine, Renal-Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652292PMC
October 2017

Sex Differences in Circulating Progenitor Cells.

J Am Heart Assoc 2017 Oct 3;6(10). Epub 2017 Oct 3.

Division of Cardiology, Emory University School of Medicine, Atlanta, GA

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http://dx.doi.org/10.1161/JAHA.117.006245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721840PMC
October 2017

Association Between Living in Food Deserts and Cardiovascular Risk.

Circ Cardiovasc Qual Outcomes 2017 Sep;10(9)

From the Emory Clinical Cardiovascular Research Institute (H.M.K., M.H., H.A., M.T., A.S.-T., M.A., K.P., K.M., L.S.S., V.V., A.A.Q.), Rollins School of Public Health, Emory University School of Medicine (Y.-A.K., V.V., T.L.), and Predictive Health Institute (G.M.), Emory University, Atlanta, GA; Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, GA (P.P., H.T.); and National Heart, Lung, and Blood Institute, Bethesda, MD (G.H.G.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.116.003532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810926PMC
September 2017

Statin therapy improves survival in patients with severe pulmonary hypertension: a propensity score matching study.

Heart Vessels 2017 Aug 16;32(8):969-976. Epub 2017 Mar 16.

Division of Cardiology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.1007/s00380-017-0957-8DOI Listing
August 2017

Progenitor Cells and Clinical Outcomes in Patients With Heart Failure.

Circ Heart Fail 2017 Aug 8;10(8). Epub 2017 Aug 8.

From the Division of Cardiology, Emory University School of Medicine, Atlanta, GA (A.S.T., M.H., P.B.S., S.S.H., A.P.K., A.A., H.M.-K., M.T., N.G., K.C., H.A., I.H., J.H.K., P.W., L.S., V.V., A.A.Q.); and Department of Biostatistics and Bioinformatics (Y.-A.K., E.M.) and Department of Hematology and Oncology, Winship Cancer Institute (E.K.W.), Emory University, Atlanta, GA.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.117.004106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809135PMC
August 2017

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

Authors:
Stephen Zewinger Marcus E Kleber Vinicius Tragante Raymond O McCubrey Amand F Schmidt Kenan Direk Ulrich Laufs Christian Werner Wolfgang Koenig Dietrich Rothenbacher Ute Mons Lutz P Breitling Herrmann Brenner Richard T Jennings Ioannis Petrakis Sarah Triem Mira Klug Alexandra Filips Stefan Blankenberg Christoph Waldeyer Christoph Sinning Renate B Schnabel Karl J Lackner Efthymia Vlachopoulou Ottar Nygård Gard Frodahl Tveitevåg Svingen Eva Ringdal Pedersen Grethe S Tell Juha Sinisalo Markku S Nieminen Reijo Laaksonen Stella Trompet Roelof A J Smit Naveed Sattar J Wouter Jukema Heinrich V Groesdonk Graciela Delgado Tatjana Stojakovic Anna P Pilbrow Vicky A Cameron A Mark Richards Robert N Doughty Yan Gong Rhonda Cooper-DeHoff Julie Johnson Markus Scholz Frank Beutner Joachim Thiery J Gustav Smith Ragnar O Vilmundarson Ruth McPherson Alexandre F R Stewart Sharon Cresci Petra A Lenzini John A Spertus Oliviero Olivieri Domenico Girelli Nicola I Martinelli Andreas Leiherer Christoph H Saely Heinz Drexel Axel Mündlein Peter S Braund Christopher P Nelson Nilesh J Samani Daniel Kofink Imo E Hoefer Gerard Pasterkamp Arshed A Quyyumi Yi-An Ko Jaana A Hartiala Hooman Allayee W H Wilson Tang Stanley L Hazen Niclas Eriksson Claes Held Emil Hagström Lars Wallentin Axel Åkerblom Agneta Siegbahn Igor Karp Christopher Labos Louise Pilote James C Engert James M Brophy George Thanassoulis Peter Bogaty Wojciech Szczeklik Marcin Kaczor Marek Sanak Salim S Virani Christie M Ballantyne Vei-Vei Lee Eric Boerwinkle Michael V Holmes Benjamin D Horne Aroon Hingorani Folkert W Asselbergs Riyaz S Patel Bernhard K Krämer Hubert Scharnagl Danilo Fliser Winfried März Thimoteus Speer

Lancet Diabetes Endocrinol 2017 07 26;5(7):534-543. Epub 2017 May 26.

Department of Internal Medicine IV, Saarland University Hospital, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/S2213-8587(17)30096-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651679PMC
July 2017

Data on the mRNA expression by in situ hybridization of Wnt signaling pathway members in the mouse uterus.

Data Brief 2017 Jun 8;12:208-212. Epub 2017 Apr 8.

School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales 2308, Australia.

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http://dx.doi.org/10.1016/j.dib.2017.03.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393313PMC
June 2017

Genetic-Variation-Driven Gene-Expression Changes Highlight Genes with Important Functions for Kidney Disease.

Am J Hum Genet 2017 Jun;100(6):940-953

Renal-Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473735PMC
June 2017

Precision Medicine Approaches to Diabetic Kidney Disease: Tissue as an Issue.

Curr Diab Rep 2017 05;17(5):30

Renal-Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 415 Curie Blvd, 415 Clinical Research Building, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s11892-017-0854-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772762PMC
May 2017

Validation Study of Maternal Recall on Breastfeeding Duration 6 Years After Childbirth.

J Hum Lact 2017 May 23;33(2):390-400. Epub 2017 Mar 23.

2 Division of Nutrition, Physical Activity and Obesity, Centers for Disease Control and Prevention, Atlanta, GA, USA.

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http://dx.doi.org/10.1177/0890334417691506DOI Listing
May 2017

Telomere Shortening, Regenerative Capacity, and Cardiovascular Outcomes.

Circ Res 2017 Mar 12;120(7):1130-1138. Epub 2016 Dec 12.

From the Division of Cardiology, Department of Medicine (M.H., I.A.M., K.W., R.R., N.A., A.A., M.O., H.M.K., A.S., K.H.M., A.A.Q., V.V.) and Department of Psychiatry and Behavioral Sciences (J.D.B.), Emory University School of Medicine, Atlanta, GA; Department of Epidemiology, Rollins School of Public Health (P.M.P., O.L., A.S., Y.V.S., B.P., V.V.), Department of Biostatistics and Bioinformatics, Rollins School of Public Health (Y.V.S., M.K., Q.L., L.W., Y.-A.K.), and Department of Hematology and Oncology, Winship Cancer Institute (J.K., E.K.W.), Emory University, Atlanta, GA; Department of Biochemistry and Biophysics, University of California, San Francisco (J.L.); Department of Epidemiology, Tulane University School of Public Health, New Orleans, LA (J.Z.); Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada (P.R.); and Department of Epidemiology, University of Florida, Gainesville (D.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.309421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376244PMC
March 2017

Depression and chest pain in patients with coronary artery disease.

Int J Cardiol 2017 Mar 23;230:420-426. Epub 2016 Dec 23.

Division of Cardiology, Emory University School of Medicine, Atlanta, GA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.12.091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881400PMC
March 2017

Differential Wnt signaling activity limits epithelial gland development to the anti-mesometrial side of the mouse uterus.

Dev Biol 2017 03 30;423(2):138-151. Epub 2017 Jan 30.

School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales 2308, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2017.01.015DOI Listing
March 2017

Pathway-Specific Aggregate Biomarker Risk Score Is Associated With Burden of Coronary Artery Disease and Predicts Near-Term Risk of Myocardial Infarction and Death.

Circ Cardiovasc Qual Outcomes 2017 03;10(3)

From the Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA (N.G., S.S.H., D.J.E., R.S.P., P.M., H.A.K., M.K., E.V., A.M.Z., S.L., L.S., V.V., A.A.Q.); Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA (Y.-A.K.); Institute of Cardiovascular Science, University College London, United Kingdom (R.S.P.); Division of Cardiology, Atlanta VA Medical Center, GA (A.M.Z.); Department of Biostatistics, Florida International University, Miami (E.V.); Department of Cardiology, University of Athens School of Medicine, Greece (D.K.); Clinical Research Centre, Copenhagen University Hospital, Denmark (C.W.T., T.P.); Stemedica Cell Technologies, Inc., San Diego, CA (S.S.); Department of Epidemiology, Emory University, Atlanta, GA (V.V.); and MedStar Heart and Vascular Institute, MedStar Washington Hospital Center, Washington, DC (S.E.E.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.115.001493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874795PMC
March 2017

The impact of moderate distance recreational running and ageing on cardiac physiology.

Heart 2017 02 16;103(3):219-226. Epub 2016 Aug 16.

Cardiovascular Performance Program, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/heartjnl-2016-310059DOI Listing
February 2017

Intravenous Allogeneic Mesenchymal Stem Cells for Nonischemic Cardiomyopathy: Safety and Efficacy Results of a Phase II-A Randomized Trial.

Circ Res 2017 Jan 16;120(2):332-340. Epub 2016 Nov 16.

From the Division of Cardiology, Department of Medicine, Stony Brook University, NY (J.B., H.A.S.); MedStar Heart and Vascular Institute, MedStar Washington Hospital Center, Washington, DC (S.E.E., M.J.L.); Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC (S.J.G., R.J.K.); Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA (A.A.Q., R.T.C.); CardioCell LLC, San Diego, CA (S.S.); Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (A.S.A., J.E.W.); Stemedica Cell Technologies Inc, San Diego, CA (N.I.T.); Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA (Y.-A.K.); Division of Cardiology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia (K.B.M.); and Center for Cardiovascular Innovation, Northwestern University Feinberg School of Medicine, Chicago, IL (M.G.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.309717DOI Listing
January 2017

Classification and Clustering Methods for Multiple Environmental Factors in Gene-Environment Interaction: Application to the Multi-Ethnic Study of Atherosclerosis.

Epidemiology 2016 11;27(6):870-8

From the aDepartment of Biostatistics and Bioinformatics, Emory University, Atlanta, GA; bDepartment of Biostatistics, University of Michigan, Ann Arbor, MI; cDepartment of Epidemiology, University of Michigan, Ann Arbor, MI; dDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, CA; and eDepartment of Epidemiology and Biostatistics, Dornsife School of Public Health at Drexel University, Philadelphia, PA.

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http://dx.doi.org/10.1097/EDE.0000000000000548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039086PMC
November 2016

Effects of a Health-Partner Intervention on Cardiovascular Risk.

J Am Heart Assoc 2016 10 11;5(10). Epub 2016 Oct 11.

Emory Clinical Cardiovascular Research Institute, Emory University, Atlanta, GA Center for the Study of Human Health, Emory University, Atlanta, GA Predictive Health Institute, Emory University, Atlanta, GA

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http://dx.doi.org/10.1161/JAHA.116.004217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121518PMC
October 2016

Age and Human Regenerative Capacity Impact of Cardiovascular Risk Factors.

Circ Res 2016 Sep 19;119(7):801-9. Epub 2016 Jul 19.

From the Division of Cardiology, Emory Clinical Cardiovascular Research Institute, Emory-Georgia Tech, Predictive Health Institute, Atlanta, GA.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026592PMC
September 2016

Platelets confound the measurement of extracellular miRNA in archived plasma.

Sci Rep 2016 09 13;6:32651. Epub 2016 Sep 13.

Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1038/srep32651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020735PMC
September 2016

Circulating Progenitor Cells Identify Peripheral Arterial Disease in Patients With Coronary Artery Disease.

Circ Res 2016 Aug 6;119(4):564-71. Epub 2016 Jun 6.

From the Division of Cardiology (S.S.H., M.A., A.Y., S.H., I.H., H.A., B.G., S.S.S., N.G., R.P., A.A.Q.) and Department of Internal Medicine, Emory University School of Medicine, Atlanta, GA (J.M., A.S.T.); and Department of Biostatistics and Bioinformatics (Y.-A.K.) and Department of Hematology and Oncology, Winship Cancer Institute (J.K., E.K.W.), Emory University, Atlanta, GA.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975640PMC
August 2016

Cardiac Structure and Function in Elite Para-cyclists with Spinal Cord Injury.

Med Sci Sports Exerc 2016 08;48(8):1431-7

1Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA; 2University of South Carolina School of Medicine Greenville, Greenville, SC; 3Department of Medicine, Greenville Health System, Greenville, SC; and 4Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA.

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http://dx.doi.org/10.1249/MSS.0000000000000921DOI Listing
August 2016

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.

Authors:
Alexander Teumer Adrienne Tin Rossella Sorice Mathias Gorski Nan Cher Yeo Audrey Y Chu Man Li Yong Li Vladan Mijatovic Yi-An Ko Daniel Taliun Alessandro Luciani Ming-Huei Chen Qiong Yang Meredith C Foster Matthias Olden Linda T Hiraki Bamidele O Tayo Christian Fuchsberger Aida Karina Dieffenbach Alan R Shuldiner Albert V Smith Allison M Zappa Antonio Lupo Barbara Kollerits Belen Ponte Bénédicte Stengel Bernhard K Krämer Bernhard Paulweber Braxton D Mitchell Caroline Hayward Catherine Helmer Christa Meisinger Christian Gieger Christian M Shaffer Christian Müller Claudia Langenberg Daniel Ackermann David Siscovick Eric Boerwinkle Florian Kronenberg Georg B Ehret Georg Homuth Gerard Waeber Gerjan Navis Giovanni Gambaro Giovanni Malerba Gudny Eiriksdottir Guo Li H Erich Wichmann Harald Grallert Henri Wallaschofski Henry Völzke Herrmann Brenner Holly Kramer I Mateo Leach Igor Rudan Hans L Hillege Jacques S Beckmann Jean Charles Lambert Jian'an Luan Jing Hua Zhao John Chalmers Josef Coresh Joshua C Denny Katja Butterbach Lenore J Launer Luigi Ferrucci Lyudmyla Kedenko Margot Haun Marie Metzger Mark Woodward Matthew J Hoffman Matthias Nauck Melanie Waldenberger Menno Pruijm Murielle Bochud Myriam Rheinberger Niek Verweij Nicholas J Wareham Nicole Endlich Nicole Soranzo Ozren Polasek Pim van der Harst Peter Paul Pramstaller Peter Vollenweider Philipp S Wild Ron T Gansevoort Rainer Rettig Reiner Biffar Robert J Carroll Ronit Katz Ruth J F Loos Shih-Jen Hwang Stefan Coassin Sven Bergmann Sylvia E Rosas Sylvia Stracke Tamara B Harris Tanguy Corre Tanja Zeller Thomas Illig Thor Aspelund Toshiko Tanaka Uwe Lendeckel Uwe Völker Vilmundur Gudnason Vincent Chouraki Wolfgang Koenig Zoltan Kutalik Jeffrey R O'Connell Afshin Parsa Iris M Heid Andrew D Paterson Ian H de Boer Olivier Devuyst Jozef Lazar Karlhans Endlich Katalin Susztak Johanne Tremblay Pavel Hamet Howard J Jacob Carsten A Böger Caroline S Fox Cristian Pattaro Anna Köttgen

Diabetes 2016 Mar 2;65(3):803-17. Epub 2015 Dec 2.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD Renal Division, Medical Center, University of Freiburg, Freiburg, Germany

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http://diabetes.diabetesjournals.org/content/early/2015/11/2
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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db15
Publisher Site
http://dx.doi.org/10.2337/db15-1313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764151PMC
March 2016

Novel Biomarker of Oxidative Stress Is Associated With Risk of Death in Patients With Coronary Artery Disease.

Circulation 2016 Jan 16;133(4):361-9. Epub 2015 Dec 16.

From Department of Medicine, Emory University School of Medicine, Atlanta, GA (R.S.P., N.G., D.J.E., S.S., S.A., H.S., A.M.Z., L.S., V.V., D.P.J., A.A.Q.); Institute of Cardiovascular Science, University College London, United Kingdom (R.S.P.); Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Atlanta, GA (Y.K.); Department of Medicine, Baptist Health South Florida, Miami, FL (E.V.); Department of Epidemiology, Rollins School of Public Health, Atlanta, GA (E.V., V.V.); and Department of Medicine, Atlanta Veterans Affairs Medical Center, Decatur, GA (A.M.Z.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722941PMC
January 2016

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.

Authors:
Cristian Pattaro Alexander Teumer Mathias Gorski Audrey Y Chu Man Li Vladan Mijatovic Maija Garnaas Adrienne Tin Rossella Sorice Yong Li Daniel Taliun Matthias Olden Meredith Foster Qiong Yang Ming-Huei Chen Tune H Pers Andrew D Johnson Yi-An Ko Christian Fuchsberger Bamidele Tayo Michael Nalls Mary F Feitosa Aaron Isaacs Abbas Dehghan Pio d'Adamo Adebowale Adeyemo Aida Karina Dieffenbach Alan B Zonderman Ilja M Nolte Peter J van der Most Alan F Wright Alan R Shuldiner Alanna C Morrison Albert Hofman Albert V Smith Albert W Dreisbach Andre Franke Andre G Uitterlinden Andres Metspalu Anke Tonjes Antonio Lupo Antonietta Robino Åsa Johansson Ayse Demirkan Barbara Kollerits Barry I Freedman Belen Ponte Ben A Oostra Bernhard Paulweber Bernhard K Krämer Braxton D Mitchell Brendan M Buckley Carmen A Peralta Caroline Hayward Catherine Helmer Charles N Rotimi Christian M Shaffer Christian Müller Cinzia Sala Cornelia M van Duijn Aude Saint-Pierre Daniel Ackermann Daniel Shriner Daniela Ruggiero Daniela Toniolo Yingchang Lu Daniele Cusi Darina Czamara David Ellinghaus David S Siscovick Douglas Ruderfer Christian Gieger Harald Grallert Elena Rochtchina Elizabeth J Atkinson Elizabeth G Holliday Eric Boerwinkle Erika Salvi Erwin P Bottinger Federico Murgia Fernando Rivadeneira Florian Ernst Florian Kronenberg Frank B Hu Gerjan J Navis Gary C Curhan George B Ehret Georg Homuth Stefan Coassin Gian-Andri Thun Giorgio Pistis Giovanni Gambaro Giovanni Malerba Grant W Montgomery Gudny Eiriksdottir Gunnar Jacobs Guo Li H-Erich Wichmann Harry Campbell Helena Schmidt Henri Wallaschofski Henry Völzke Hermann Brenner Heyo K Kroemer Holly Kramer Honghuang Lin I Mateo Leach Ian Ford Idris Guessous Igor Rudan Inga Prokopenko Ingrid Borecki Iris M Heid Ivana Kolcic Ivana Persico J Wouter Jukema James F Wilson Janine F Felix Jasmin Divers Jean-Charles Lambert Jeanette M Stafford Jean-Michel Gaspoz Jennifer A Smith Jessica D Faul Jie Jin Wang Jingzhong Ding Joel N Hirschhorn John Attia John B Whitfield John Chalmers Jorma Viikari Josef Coresh Joshua C Denny Juha Karjalainen Jyotika K Fernandes Karlhans Endlich Katja Butterbach Keith L Keene Kurt Lohman Laura Portas Lenore J Launer Leo-Pekka Lyytikäinen Loic Yengo Lude Franke Luigi Ferrucci Lynda M Rose Lyudmyla Kedenko Madhumathi Rao Maksim Struchalin Marcus E Kleber Margherita Cavalieri Margot Haun Marilyn C Cornelis Marina Ciullo Mario Pirastu Mariza de Andrade Mark A McEvoy Mark Woodward Martin Adam Massimiliano Cocca Matthias Nauck Medea Imboden Melanie Waldenberger Menno Pruijm Marie Metzger Michael Stumvoll Michele K Evans Michele M Sale Mika Kähönen Mladen Boban Murielle Bochud Myriam Rheinberger Niek Verweij Nabila Bouatia-Naji Nicholas G Martin Nick Hastie Nicole Probst-Hensch Nicole Soranzo Olivier Devuyst Olli Raitakari Omri Gottesman Oscar H Franco Ozren Polasek Paolo Gasparini Patricia B Munroe Paul M Ridker Paul Mitchell Paul Muntner Christa Meisinger Johannes H Smit Peter Kovacs Philipp S Wild Philippe Froguel Rainer Rettig Reedik Mägi Reiner Biffar Reinhold Schmidt Rita P S Middelberg Robert J Carroll Brenda W Penninx Rodney J Scott Ronit Katz Sanaz Sedaghat Sarah H Wild Sharon L R Kardia Sheila Ulivi Shih-Jen Hwang Stefan Enroth Stefan Kloiber Stella Trompet Benedicte Stengel Stephen J Hancock Stephen T Turner Sylvia E Rosas Sylvia Stracke Tamara B Harris Tanja Zeller Tatijana Zemunik Terho Lehtimäki Thomas Illig Thor Aspelund Tiit Nikopensius Tonu Esko Toshiko Tanaka Ulf Gyllensten Uwe Völker Valur Emilsson Veronique Vitart Ville Aalto Vilmundur Gudnason Vincent Chouraki Wei-Min Chen Wilmar Igl Winfried März Wolfgang Koenig Wolfgang Lieb Ruth J F Loos Yongmei Liu Harold Snieder Peter P Pramstaller Afshin Parsa Jeffrey R O'Connell Katalin Susztak Pavel Hamet Johanne Tremblay Ian H de Boer Carsten A Böger Wolfram Goessling Daniel I Chasman Anna Köttgen W H Linda Kao Caroline S Fox

Nat Commun 2016 Jan 21;7:10023. Epub 2016 Jan 21.

NHLBI's Framingham Heart Study and the Center for Population Studies, 73 Mt Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA.

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http://dx.doi.org/10.1038/ncomms10023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735748PMC
January 2016

Soluble Urokinase Receptor and Chronic Kidney Disease.

N Engl J Med 2015 Nov 5;373(20):1916-25. Epub 2015 Nov 5.

From the Division of Cardiology, Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine (S.S.H., Y.-A.K., M.A., L.S.S., S.L., A.A.Q.), and the Department of Biostatistics and Bioinformatics, Emory University (Y.-A.K.) - both in Atlanta; the Department of Medicine, Harvard Medical School, Boston, and Division of Nephrology, Massachusetts General Hospital, Charlestown - both in Massachusetts (S.S.); the Department of Pediatrics, NYU Langone Medical Center, New York (H.T.); and the Department of Medicine, Rush University Medical Center (S.W., M.M.A., C.W., A.L.F., J.R.), and the Women's Interagency HIV Study/CORE Center of Cook County (A.L.H., A.L.F.) - both in Chicago.

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http://dx.doi.org/10.1056/NEJMoa1506362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701036PMC
November 2015

Functional genomic annotation of genetic risk loci highlights inflammation and epithelial biology networks in CKD.

J Am Soc Nephrol 2015 Mar 17;26(3):692-714. Epub 2014 Sep 17.

Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

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http://dx.doi.org/10.1681/ASN.2014010028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341476PMC
March 2015

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development.

Nat Med 2015 Jan 1;21(1):37-46. Epub 2014 Dec 1.

Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/nm.3762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444078PMC
January 2015

Epigenetics: a new way to look at kidney diseases.

Nephrol Dial Transplant 2014 Oct 27;29(10):1821-7. Epub 2014 Mar 27.

Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/ndt/gfu026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173816PMC
October 2014

Declines with age in childhood asthma symptoms and health care use: an adjustment for evaluations.

Health Educ Behav 2014 Oct;41(5):539-49

Center for Managing Chronic Disease, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1177/1090198114547513DOI Listing
October 2014

Variability in urinary phthalate metabolite levels across pregnancy and sensitive windows of exposure for the risk of preterm birth.

Environ Int 2014 Sep 13;70:118-24. Epub 2014 Jun 13.

Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2014.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104181PMC
September 2014

Interaction of fatty acid genotype and diet on changes in colonic fatty acids in a Mediterranean diet intervention study.

Cancer Prev Res (Phila) 2013 Nov 10;6(11):1212-21. Epub 2013 Sep 10.

University of Michigan, 1500 E. Medical Center Drive, Room 2150 Cancer Center, Ann Arbor, MI 48109-5930.

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http://dx.doi.org/10.1158/1940-6207.CAPR-13-0131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840911PMC
November 2013

Novel likelihood ratio tests for screening gene-gene and gene-environment interactions with unbalanced repeated-measures data.

Genet Epidemiol 2013 Sep 24;37(6):581-91. Epub 2013 Jun 24.

Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109-2029, USA.

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http://dx.doi.org/10.1002/gepi.21744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009698PMC
September 2013

NF-κB activation in myeloid cells mediates ventilator-induced lung injury.

Respir Res 2013 Jul 3;14:69. Epub 2013 Jul 3.

Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung 804, Taiwan.

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http://dx.doi.org/10.1186/1465-9921-14-69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708752PMC
July 2013

Epigenomics: the science of no-longer-junk DNA. Why study it in chronic kidney disease?

Semin Nephrol 2013 Jul;33(4):354-62

Renal, Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.semnephrol.2013.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815533PMC
July 2013

The relationship of season of birth to asthma and allergy in urban African American children from 10 to 13 years of age.

J Asthma 2012 Dec;49(10):1037-43

Center for Managing Chronic Disease, University of Michigan, Ann Arbor, MI 48109-2029, USA.

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http://dx.doi.org/10.3109/02770903.2012.739239DOI Listing
December 2012

Principal interactions analysis for repeated measures data: application to gene-gene and gene-environment interactions.

Stat Med 2012 Sep 13;31(22):2531-51. Epub 2012 Mar 13.

Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1002/sim.5315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046647PMC
September 2012

Outcomes associated with a negotiated asthma treatment plan.

Chron Respir Dis 2012 Aug;9(3):175-82

Center for Managing Chronic Disease, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1177/1479972312452437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699195PMC
August 2012

An all-statistics, high-speed algorithm for the analysis of copy number variation in genomes.

Nucleic Acids Res 2011 Jul 16;39(13):e89. Epub 2011 May 16.

Graduate Institute of Systems Biology and Bioinformatics, National Central University, Chungli, Taiwan 32001.

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http://dx.doi.org/10.1093/nar/gkr137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141250PMC
July 2011

Biomaterials for the feeder-free culture of human embryonic stem cells and induced pluripotent stem cells.

Chem Rev 2011 May 23;111(5):3021-35. Epub 2011 Feb 23.

Department of Chemical and Materials Engineering, National Central University, Jhongli, Taoyuan, 32001 Taiwan.

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http://pubs.acs.org/doi/abs/10.1021/cr1003612
Publisher Site
http://dx.doi.org/10.1021/cr1003612DOI Listing
May 2011