Publications by authors named "Yi E Sun"

51Publications

Graded and pan-neural disease phenotypes of Rett Syndrome linked with dosage of functional MeCP2.

Protein Cell 2020 Aug 27. Epub 2020 Aug 27.

Shanghai Institute of Stem Cell Research and Clinical Translation, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.

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http://dx.doi.org/10.1007/s13238-020-00773-zDOI Listing
August 2020

Tet2-mediated epigenetic drive for astrocyte differentiation from embryonic neural stem cells.

Cell Death Discov 2020 29;6:30. Epub 2020 Apr 29.

1Shanghai Institute of Stem Cell Research and Clinical Translation, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200092 China.

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http://dx.doi.org/10.1038/s41420-020-0264-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190615PMC
April 2020

TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson's disease.

Proc Natl Acad Sci U S A 2017 10 18;114(40):10773-10778. Epub 2017 Sep 18.

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322;

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http://dx.doi.org/10.1073/pnas.1713969114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635931PMC
October 2017

MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life.

Proc Natl Acad Sci U S A 2017 08 8;114(34):9188-9193. Epub 2017 Aug 8.

Stem Cell Translational Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China 200092;

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http://dx.doi.org/10.1073/pnas.1706069114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576812PMC
August 2017

α-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation.

Proc Natl Acad Sci U S A 2017 01 17;114(5):1183-1188. Epub 2017 Jan 17.

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322;

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http://dx.doi.org/10.1073/pnas.1618627114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293033PMC
January 2017

Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease.

Nat Commun 2015 Nov 9;6:8762. Epub 2015 Nov 9.

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1038/ncomms9762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659940PMC
November 2015

Transcriptome analyses reveal molecular mechanisms underlying functional recovery after spinal cord injury.

Proc Natl Acad Sci U S A 2015 Oct 12;112(43):13360-5. Epub 2015 Oct 12.

Department of Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China; Department of Neurobiology, School of Basic Medical Sciences, Captial Medical University, Beijing 100069, China

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http://dx.doi.org/10.1073/pnas.1510176112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629389PMC
October 2015

NT3-chitosan elicits robust endogenous neurogenesis to enable functional recovery after spinal cord injury.

Proc Natl Acad Sci U S A 2015 Oct 12;112(43):13354-9. Epub 2015 Oct 12.

Department of Neurobiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China; Department of Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China;

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http://dx.doi.org/10.1073/pnas.1510194112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629318PMC
October 2015

Circadian rhythm disruption in a mouse model of Rett syndrome circadian disruption in RTT.

Neurobiol Dis 2015 May 14;77:155-64. Epub 2015 Mar 14.

Laboratory of Circadian and Sleep Medicine, Department of Psychiatry, University of California, Los Angeles, 760 Westwood Plaza, Los Angeles 90095-1759, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2015.03.009DOI Listing
May 2015

Spatiotemporally different origins of NG2 progenitors produce cortical interneurons versus glia in the mammalian forebrain.

Proc Natl Acad Sci U S A 2014 May 5;111(20):7444-9. Epub 2014 May 5.

Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, University of California, Los Angeles, CA 90095; andTranslational Stem Cell Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai 200092, China

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http://dx.doi.org/10.1073/pnas.1400422111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034245PMC
May 2014

Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward.

Nat Neurosci 2014 Feb 12;17(2):254-61. Epub 2014 Jan 12.

1] Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, California, USA. [2] Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California, USA. [3] Brain Research Institute, University of California, Los Angeles, Los Angeles, California, USA. [4] David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nn.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008330PMC
February 2014

Genetic modification of mesenchymal stem cells in spinal cord injury repair strategies.

Biosci Trends 2013 Oct;7(5):202-8

Translational Center for Stem Cell Research, Tongji Hospital, Department of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China.

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October 2013

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing.

Nature 2013 Aug 28;500(7464):593-7. Epub 2013 Jul 28.

Translational Center for Stem Cell Research, Tongji Hospital, Department of Regenerative Medicine, Tongji University School of Medicine, Shanghai 200065, China.

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http://dx.doi.org/10.1038/nature12364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950944PMC
August 2013

Epigenetic regulation of stem cells differentiating along the neural lineage.

Curr Opin Neurobiol 2012 Oct 24;22(5):762-7. Epub 2012 Jul 24.

Intellectual and Developmental Disabilities Research Center, Departments of Psychiatry & Behavioral Sciences and Molecular & Medical Pharmacology, Semel Institute for Neuroscience, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095, United States.

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http://dx.doi.org/10.1016/j.conb.2012.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489177PMC
October 2012

Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging.

J Neurosci 2011 Dec;31(49):17800-10

Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California 90024, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3878-11.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278324PMC
December 2011

The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory.

Nat Neurosci 2011 Aug 14;14(9):1115-7. Epub 2011 Aug 14.

Intellectual Development and Disabilities Research Center, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nn.2891DOI Listing
August 2011

Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration.

J Neurosci 2011 Jun;31(22):8306-19

Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0567-11.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500097PMC
June 2011

Genome-wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndrome.

Proc Natl Acad Sci U S A 2010 Oct 4;107(42):18161-6. Epub 2010 Oct 4.

Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1073/pnas.1005595107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964235PMC
October 2010

Quantification of O-glycosylation stoichiometry and dynamics using resolvable mass tags.

Nat Chem Biol 2010 Sep 25;6(9):645-51. Epub 2010 Jul 25.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, USA.

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http://dx.doi.org/10.1038/nchembio.412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924450PMC
September 2010

A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone.

Proc Natl Acad Sci U S A 2010 Feb 25;107(6):2687-92. Epub 2010 Jan 25.

Department of Pathology, Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1073/pnas.0913572107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823863PMC
February 2010

How the epigenome contributes to the development of psychiatric disorders.

Dev Psychobiol 2010 May;52(4):331-42

Queensland Brain Institute, University of Queensland, Brisbane, QC 4072, Australia.

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http://dx.doi.org/10.1002/dev.20424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946415PMC
May 2010

Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors.

PLoS One 2009 Sep 28;4(9):e7192. Epub 2009 Sep 28.

Rutgers Stem Cell Research Center, Rutgers University, Piscataway, New Jersey, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007192PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745660PMC
September 2009

Transcriptional regulation of neuronal differentiation: the epigenetic layer of complexity.

Biochim Biophys Acta 2008 Aug 28;1779(8):432-7. Epub 2008 Jul 28.

Mental Retardation Research Center, David Geffen School of Medicine, University of California Los Angeles, USA.

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http://dx.doi.org/10.1016/j.bbagrm.2008.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211633PMC
August 2008

CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain.

Proc Natl Acad Sci U S A 2008 Jan 14;105(3):1026-31. Epub 2008 Jan 14.

Mental Retardation Research Center and Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1073/pnas.0710000105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242680PMC
January 2008

Neurons or glia? Can SHP2 know it all?

Sci STKE 2007 Oct 30;2007(410):pe58. Epub 2007 Oct 30.

Mental Retardation Research Center, Department of Molecular and Medical Pharmacology, Neuropsychiatric Institute, David Geffen School of Medicine, University of California Los Angeles, 635 Charles E. Young Drive South, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1126/stke.4102007pe58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211625PMC
October 2007

A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation.

Chem Biol 2007 Sep;14(9):1019-30

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S107455210700285
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http://dx.doi.org/10.1016/j.chembiol.2007.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758915PMC
September 2007

Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines.

Proc Natl Acad Sci U S A 2007 Aug 10;104(34):13821-6. Epub 2007 Aug 10.

Mental Retardation Research Center, David Geffen School of Medicine at University of California, Los Angeles, Neuroscience Research Building Room 351, 635 Charles E. Young Drive South, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1073/pnas.0706199104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959466PMC
August 2007

Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear.

Learn Mem 2007 Apr 6;14(4):268-76. Epub 2007 Apr 6.

Department of Psychiatry and Biobehavioral Sciences, Brain Research Institute, Semel Institute for Neuroscience and Human Behavior, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1101/lm.500907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2216532PMC
April 2007

Probing the dynamics of O-GlcNAc glycosylation in the brain using quantitative proteomics.

Nat Chem Biol 2007 Jun 13;3(6):339-48. Epub 2007 May 13.

Division of Chemistry and Chemical Engineering and Howard Hughes Medical Institute, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1038/nchembio881DOI Listing
June 2007

Prokineticin 2 is a target gene of proneural basic helix-loop-helix factors for olfactory bulb neurogenesis.

J Biol Chem 2007 Mar 26;282(10):6917-21. Epub 2007 Jan 26.

Department of Pharmacology, University of California, Irvine, California 92697, USA.

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http://dx.doi.org/10.1074/jbc.C600290200DOI Listing
March 2007

Glial cells more than support cells?

Authors:
Fei He Yi E Sun

Int J Biochem Cell Biol 2007 2;39(4):661-5. Epub 2006 Nov 2.

Department of Molecular & Medical Pharmacology, David Geffen School of Medicine at University of California, Los Angeles, USA.

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http://dx.doi.org/10.1016/j.biocel.2006.10.022DOI Listing
June 2007

Neural progenitors populate the cerebrospinal fluid of preterm patients with hydrocephalus.

J Pediatr 2006 Mar;148(3):337-340

Ahmanson Pediactric Center, Division of Neonatology, Cedars-Sinai Medical Center, The David Geffen School of Medicine at UCLA, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1016/j.jpeds.2005.09.035DOI Listing
March 2006

The ups and downs of BDNF in Rett syndrome.

Authors:
Yi E Sun Hao Wu

Neuron 2006 Feb;49(3):321-3

Department of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute, University of California, Los Angeles, 635 Charles E. Young Drive South, Los Angeles, California 91301, USA.

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http://dx.doi.org/10.1016/j.neuron.2006.01.014DOI Listing
February 2006

Coupling of cell migration with neurogenesis by proneural bHLH factors.

Proc Natl Acad Sci U S A 2006 Jan 23;103(5):1319-24. Epub 2006 Jan 23.

Mental Retardation Research Center, Dept. of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute, David Geffen School of Medicine, University of California-Los Angeles, 635 Charles E. Young Drive South, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1073/pnas.0510419103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1345712PMC
January 2006

Decatenation checkpoint deficiency in stem and progenitor cells.

Cancer Cell 2005 Dec;8(6):479-84

Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1016/j.ccr.2005.11.004DOI Listing
December 2005

The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands.

J Cell Biol 2005 Sep 6;170(6):983-92. Epub 2005 Sep 6.

Department of Biological Chemistry, Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1083/jcb.200503113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171428PMC
September 2005

DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling.

Development 2005 Aug;132(15):3345-56

Department of Human Genetics, University of California at Los Angeles, 695 Charles Young Drive South, Los Angeles, CA 90095, USA.

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http://dev.biologists.org/cgi/doi/10.1242/dev.01912
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http://dx.doi.org/10.1242/dev.01912DOI Listing
August 2005

A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis.

Nat Neurosci 2005 May 24;8(5):616-25. Epub 2005 Apr 24.

Department of Molecular & Medical Pharmacology, Neuropsychiatric Institute, University of California Los Angeles, Los Angeles, California 90024, USA.

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http://dx.doi.org/10.1038/nn1440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222251PMC
May 2005

To learn better, keep the HAT on.

Neuron 2004 Jun;42(6):879-81

Department of Psychiatry and Beiobehavioral Sciences, Neuropsychiatric Institute, University of California, Los Angeles 90095, USA.

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http://dx.doi.org/10.1016/j.neuron.2004.06.007DOI Listing
June 2004

DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation.

Science 2003 Oct;302(5646):890-3

Neuroscience Interdepartmental Program, UCLA School of Medicine, 760 Westwood Plaza, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1126/science.1090842DOI Listing
October 2003