Yen Ying Lim

Yen Ying Lim

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Yen Ying Lim

Publications by authors named "Yen Ying Lim"

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Use of an experimental language acquisition paradigm for standardized neuropsychological assessment of learning: A pilot study in young and older adults.

J Clin Exp Neuropsychol 2020 Feb 13;42(1):55-65. Epub 2019 Sep 13.

Melbourne Dementia Research Centre, The Florey Institute of Neuroscience and Mental Health, Parkville, Australia.

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http://dx.doi.org/10.1080/13803395.2019.1665626DOI Listing
February 2020

The Volunteer Dementia and Delirium Care (VDDC) program: An exploration of perceived barriers and enablers to implementation in an acute and subacute metropolitan hospital.

Australas J Ageing 2019 Nov 6. Epub 2019 Nov 6.

Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/ajag.12726DOI Listing
November 2019

The Volunteer Dementia and Delirium Care (VDDC)©: A pre-implementation study exploring perceived acceptability to implementing the program in an acute and subacute metropolitan hospital.

Australas J Ageing 2019 Oct 15. Epub 2019 Oct 15.

Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/ajag.12725DOI Listing
October 2019

Sensitivity of a Preclinical Alzheimer's Cognitive Composite (PACC) to amyloid β load in preclinical Alzheimer's disease.

J Clin Exp Neuropsychol 2019 Aug 29;41(6):591-600. Epub 2019 Mar 29.

a The Florey Institute of Neuroscience and Mental Health , The University of Melbourne , Melbourne , VIC , Australia.

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http://dx.doi.org/10.1080/13803395.2019.1593949DOI Listing
August 2019

Determining clinically meaningful decline in preclinical Alzheimer disease.

Neurology 2019 07 9;93(4):e322-e333. Epub 2019 Jul 9.

From the Center for Imaging of Neurodegenerative Diseases (M.W., R.S.M.), Department of Veterans Affairs Medical Center; Departments of Radiology and Biomedical Imaging (P.S.I., M.W.) and Psychiatry (P.S.I., R.S.M.), University of California, San Francisco; Clinical Memory Research Unit, Faculty of Medicine (P.S.I., E.S., S.P., O.H., N.M.), Memory Clinic (E.S., S.P., O.H.) and Department of Neurology (N.M.), Skåne University Hospital, and Wallenberg Center for Molecular Medicine (N.M.), Lund University, Sweden; Department of Neurology and Neurological Sciences (E.M.), Stanford University, CA; The Florey Institute (Y.Y.L., C.L.M., P.T.M.), The University of Melbourne; and CogState (P.T.M.), Melbourne, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000007831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669933PMC
July 2019

Klotho allele status is not associated with Aβ and APOE ε4-related cognitive decline in preclinical Alzheimer's disease.

Neurobiol Aging 2019 04 6;76:162-165. Epub 2019 Jan 6.

Collaborative Genomics Group, Centre of Excellence for Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia; Cooperative Research Centre for Mental Health, Carlton South, Victoria, Australia; School of Pharmacy and Biomedical Sciences, Faculty of Health Sciences, Curtin Health Innovation Research Institute, Curtin University, Bentley, Western Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.12.014DOI Listing
April 2019

The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.

Mol Psychiatry 2019 Mar 21. Epub 2019 Mar 21.

Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.

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http://dx.doi.org/10.1038/s41380-019-0404-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754794PMC
March 2019

The Healthy Brain Project: An Online Platform for the Recruitment, Assessment, and Monitoring of Middle-Aged Adults at Risk of Developing Alzheimer's Disease.

J Alzheimers Dis 2019 ;68(3):1211-1228

Melbourne Dementia Research Centre, The Florey Institute of Neuroscience and Mental Health and The University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.3233/JAD-181139DOI Listing
January 2019

Estimates of age-related memory decline are inflated by unrecognized Alzheimer's disease.

Neurobiol Aging 2018 10 11;70:170-179. Epub 2018 Jun 11.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia; CogState Ltd., Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.06.005DOI Listing
October 2018

Amyloid burden and incident depressive symptoms in preclinical Alzheimer's disease.

J Affect Disord 2018 03 3;229:269-274. Epub 2018 Jan 3.

Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia; CogState Ltd., Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jad.2017.12.101DOI Listing
March 2018

genotype and early β-amyloid accumulation in older adults without dementia.

Neurology 2017 Sep 9;89(10):1028-1034. Epub 2017 Aug 9.

From the Florey Institute of Neuroscience and Mental Health (Y.Y.L.), The University of Melbourne, Parkville, Australia; and the Department of Neurology and Neurological Sciences (E.C.M.), Stanford University, CA.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000004336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589795PMC
September 2017

Using Robust Normative Data to Investigate the Neuropsychology of Cognitive Aging.

Arch Clin Neuropsychol 2017 Mar;32(2):142-154

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.1093/arclin/acw106DOI Listing
March 2017

Plasma Cortisol, Brain Amyloid-β, and Cognitive Decline in Preclinical Alzheimer's Disease: A 6-Year Prospective Cohort Study.

Biol Psychiatry Cogn Neurosci Neuroimaging 2017 01 7;2(1):45-52. Epub 2016 Sep 7.

The Florey Institute, The University of Melbourne, Parkville, Victoria; Department of Medicine, Austin Health, The University of Melbourne, Heidelberg; Cogstate Ltd., Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.bpsc.2016.08.006DOI Listing
January 2017

β-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and Men.

Am J Geriatr Psychiatry 2016 12 17;24(12):1191-1195. Epub 2016 Aug 17.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT; U.S. Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, CT.

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http://dx.doi.org/10.1016/j.jagp.2016.08.007DOI Listing
December 2016

Performance on the Cogstate Brief Battery Is Related to Amyloid Levels and Hippocampal Volume in Very Mild Dementia.

J Mol Neurosci 2016 Nov 1;60(3):362-370. Epub 2016 Sep 1.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 155 Oak Street, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1007/s12031-016-0822-8DOI Listing
November 2016

Cognitive impairment and decline in cognitively normal older adults with high amyloid-β: A meta-analysis.

Alzheimers Dement (Amst) 2017 18;6:108-121. Epub 2016 Oct 18.

The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia; CRC for Mental Health, Carlton South, Victoria, Australia; Cogstate Ltd., Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.dadm.2016.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315443PMC
October 2016

Disclosure of positron emission tomography amyloid imaging results: A preliminary study of safety and tolerability.

Alzheimers Dement 2016 Apr 30;12(4):454-8. Epub 2015 Dec 30.

Department of Neurology, Warren Alpert Medical School of Brown University, Providence, RI, USA; Lifespan Clinical Research Center, Rhode Island Hospital, Providence, RI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2015.09.005DOI Listing
April 2016

Aβ-related memory decline in APOE ε4 noncarriers: Implications for Alzheimer disease.

Neurology 2016 04 30;86(17):1635-42. Epub 2016 Mar 30.

From The Florey Institute of Neuroscience and Mental Health (Y.Y.L., V.L.V., C.F., C.L.M., P.M.), The University of Melbourne, Parkville; Centre of Excellence for Alzheimer's Disease Research and Care (S.M.L., T.P., S.R.-S., R.N.M.), Edith Cowan University, Joondalup, Australia; Department of Psychiatry (R.H.P.), Yale University School of Medicine, New Haven, CT; Academic Unit for Psychiatry of Old Age (D.A.), St. Vincent's Health, The University of Melbourne, Kew; National Ageing Research Institute (D.A.), Parkville, Australia; Department of Neurology (P.J.S.), Warren Alpert Medical School of Brown University, Providence, RI; Commonwealth Scientific Industrial Research Organization (CSIRO) Preventative Health National Research Flagship (O.S., P.B.), Australian e-Health Research Centre-BiaMedIA, Brisbane; Departments of Nuclear Medicine and Centre for PET (V.L.V., C.C.R.) and Medicine (V.L.V., C.C.R.), Austin Health, Heidelberg; Sir James McCusker Alzheimer's Disease Research Unit (S.M.L., T.P.), Hollywood Private Hospital, Perth; Co-operative Research Centre for Mental Health (S.M.L., T.P.), Carlton South; and CogState Ltd. (P.M.), Melbourne, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000002604DOI Listing
April 2016

Disruption of cholinergic neurotransmission exacerbates Aβ-related cognitive impairment in preclinical Alzheimer's disease.

Neurobiol Aging 2015 Oct 10;36(10):2709-15. Epub 2015 Jul 10.

Department of Neurology, Warren Alpert Medical School of Brown University, Providence, RI, USA; Interdisciplinary Neuroscience Program, University of Rhode Island, Kingston, RI, USA; Lifespan Clinical Research Center, Rhode Island Hospital, Providence, RI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.07.009DOI Listing
October 2015

Anxiety symptoms, cerebral amyloid burden and memory decline in healthy older adults without dementia: 3-year prospective cohort study.

Br J Psychiatry 2014 13;204:400-1. Epub 2014 Feb 13.

Robert H. Pietrzak, PhD, MPH, J. Cobb Scott, PhD, United States Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven and Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA; Alexander Neumeister, MD, Departments of Psychiatry and Radiology, New York University School of Medicine, New York, USA; Yen Ying Lim, PhD, The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia; David Ames, MD, Academic Unit for Psychiatry of Old Age, St Vincent's Health, Department of Psychiatry, The University of Melbourne, Kew and National Ageing Research Institute, Parkville, Victoria, Australia; Kathryn A. Ellis, PhD, The Florey Institute of Neuroscience and Mental Health, Parkville, Academic Unit for Psychiatry of Old Age, St Vincent's Health, Department of Psychiatry, The University of Melbourne, Kew and National Ageing Research Institute, Parkville, Victoria, Australia; Karra Harrington, BA, The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia; Nicola T. Lautenschlager, MD, Academic Unit for Psychiatry of Old Age, St Vincent's Health, Department of Psychiatry, The University of Melbourne, Kew, Victoria and School of Psychiatry and Clinical Neurosciences and WA Centre for Health & Ageing, The University of Western Australia, Perth, Australia; Cassandra Szoeke, MD, National Ageing Research Institute, Parkville, Mental Health Research Institute, The University of Melbourne, Parkville and CSIRO Preventative Health Flagship, Parkville, Victoria, Australia; Ralph N. Martins, PhD, Centre of Excellence for Alzheimer's Disease Research and Care, School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Perth, Western Australia, Australia; Colin L. Masters, MD, The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia; Victor L. Villemagne, MD, The Flor

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http://bjp.rcpsych.org/content/bjprcpsych/204/5/400.full.pdf
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http://bjp.rcpsych.org/cgi/doi/10.1192/bjp.bp.113.134239
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http://dx.doi.org/10.1192/bjp.bp.113.134239DOI Listing
September 2015

Amyloid-β related memory decline is not associated with subjective or informant rated cognitive impairment in healthy adults.

J Alzheimers Dis 2015 ;43(2):677-86

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia Cogstate Ltd., Melbourne, VIC, Australia.

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http://dx.doi.org/10.3233/JAD-140678DOI Listing
July 2015

APOE ε4 moderates amyloid-related memory decline in preclinical Alzheimer's disease.

Neurobiol Aging 2015 Mar 11;36(3):1239-44. Epub 2014 Dec 11.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia; Cogstate Ltd., Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.008DOI Listing
March 2015

Trajectories of memory decline in preclinical Alzheimer's disease: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of ageing.

Neurobiol Aging 2015 Mar 20;36(3):1231-8. Epub 2014 Dec 20.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia; Cogstate Ltd, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.015DOI Listing
March 2015

Amyloid-β, anxiety, and cognitive decline in preclinical Alzheimer disease: a multicenter, prospective cohort study.

JAMA Psychiatry 2015 Mar;72(3):284-91

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia11Cogstate Ltd, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1001/jamapsychiatry.2014.2476DOI Listing
March 2015

Relationships between performance on the Cogstate Brief Battery, neurodegeneration, and Aβ accumulation in cognitively normal older adults and adults with MCI.

Arch Clin Neuropsychol 2015 Feb 2;30(1):49-58. Epub 2014 Dec 2.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia Cogstate Ltd., Melbourne, VIC, Australia.

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http://dx.doi.org/10.1093/arclin/acu068DOI Listing
February 2015

Amyloid-beta and depression in healthy older adults: a systematic review.

Aust N Z J Psychiatry 2015 Jan 20;49(1):36-46. Epub 2014 Nov 20.

Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia CogState Ltd., Melbourne, Victoria, Australia.

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http://journals.sagepub.com/doi/10.1177/0004867414557161
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http://dx.doi.org/10.1177/0004867414557161DOI Listing
January 2015

Aβ and cognitive change: examining the preclinical and prodromal stages of Alzheimer's disease.

Alzheimers Dement 2014 Nov 28;10(6):743-751.e1. Epub 2014 Feb 28.

Department of Nuclear Medicine and Centre for PET, Austin Health, Heidelberg, Victoria, Australia; Department of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jalz.2013.11.005DOI Listing
November 2014

Microdosing of scopolamine as a "cognitive stress test": rationale and test of a very low dose in an at-risk cohort of older adults.

Alzheimers Dement 2014 Mar;10(2):262-7

CogState, Ltd., Melbourne, Victoria, Australia; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jalz.2014.01.009DOI Listing
March 2014

The association of Aβ amyloid and composite cognitive measures in healthy older adults and MCI.

Int Psychogeriatr 2013 Oct 18;25(10):1667-77. Epub 2013 Jul 18.

Mental Health Research Institute, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1017/S1041610213001087DOI Listing
October 2013

Aβ amyloid, cognition, and APOE genotype in healthy older adults.

Alzheimers Dement 2013 Sep 14;9(5):538-45. Epub 2012 Nov 14.

Department of Psychiatry, University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1016/j.jalz.2012.07.004DOI Listing
September 2013

Short term stability of verbal memory impairment in mild cognitive impairment and Alzheimer's disease measured using the International Shopping List Test.

J Clin Exp Neuropsychol 2012 29;34(8):853-63. Epub 2012 May 29.

Department of Psychiatry, University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1080/13803395.2012.689815DOI Listing
February 2013

A process-based approach to characterizing the effect of acute alprazolam challenge on visual paired associate learning and memory in healthy older adults.

Hum Psychopharmacol 2012 Nov 2;27(6):549-58. Epub 2012 Oct 2.

National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, CT, USA.

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http://dx.doi.org/10.1002/hup.2263DOI Listing
November 2012

Preliminary data on the effect of culture on the assessment of Alzheimer's disease-related verbal memory impairment with the International Shopping List Test.

Arch Clin Neuropsychol 2012 Mar 23;27(2):136-47. Epub 2011 Dec 23.

Department of Psychiatry, University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1093/arclin/acr102DOI Listing
March 2012

A method for cross-cultural adaptation of a verbal memory assessment.

Behav Res Methods 2009 Nov;41(4):1190-200

RMIT University, Bundoora, Australia.

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http://dx.doi.org/10.3758/BRM.41.4.1190DOI Listing
November 2009