Publications by authors named "Yelena Kemel"

22Publications

Targeting Germline- and Tumor-Associated Nucleotide Excision Repair Defects in Cancer.

Authors:
Sabine Topka Zoe Steinsnyder Vignesh Ravichandran Kaitlyn Tkachuk Yelena Kemel Chaitanya Bandlamudi Mogens Winkel Madsen Helena Furberg Ouathek Ouerfelli Charles M Rudin Gopa Iyer Steven M Lipkin Semanti Mukherjee David B Solit Michael F Berger Dean F Bajorin Jonathan E Rosenberg Barry S Taylor Elisa de Stanchina Joseph Vijai Kenneth Offit

Clin Cancer Res 2020 Nov 16. Epub 2020 Nov 16.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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November 2020

Pathogenic Loss-of-Function Germline Mutations in Patients With Solid Tumors.

Authors:
Michael F Walsh Rosalba Sacca Temima Wildman Kimberly Amoroso Jennifer Kennedy Liying Zhang Ozge Birsoy Diana Mandelker Zoe Steinsnyder Alicia Latham Maria I Carlo Karen Cadoo Yelena Kemel Mark Robson Zsofia K Stadler Kenneth Offit

JCO Precis Oncol 2019 23;3. Epub 2019 Oct 23.

Memorial Sloan Kettering Cancer Center, New York, NY.

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October 2019

Fumarate hydratase c.914T > C (p.Phe305Ser) is a pathogenic variant associated with hereditary leiomyomatosis and renal cell cancer syndrome.

Authors:
Kelsey E Breen Maria I Carlo Yelena Kemel Anna Maio Ying-Bei Chen Liying Zhang Ozge Ceyhan-Birsoy Diana Mandelker

Mol Genet Genomic Med 2020 08 28;8(8):e1293. Epub 2020 May 28.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.

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August 2020

11p15.5 epimutations in children with Wilms tumor and hepatoblastoma detected in peripheral blood.

Authors:
Elise M Fiala Michael V Ortiz Jennifer A Kennedy Dominik Glodzik Megan Harlan Fleischut Kelly A Duffy Evan R Hathaway Todd Heaton Justin T Gerstle Peter Steinherz Neerav Shukla Nicole McNeer Kaitlyn Tkachuk Nancy Bouvier Karen Cadoo Maria I Carlo Alicia Latham Marianne Dubard Gault Vijai Joseph Yelena Kemel Alex Kentsis Zsofia Stadler Michael La Quaglia Elli Papaemmanuil Danielle Friedman Arupa Ganguly Andrew Kung Kenneth Offit Jennifer M Kalish Michael F Walsh

Cancer 2020 Jul 22;126(13):3114-3121. Epub 2020 Apr 22.

Division of Clinical Genetics, Memorial Sloan Kettering Cancer Center, New York, New York.

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July 2020

Germline alterations in patients with biliary tract cancers: A spectrum of significant and previously underappreciated findings.

Authors:
Hannah Maynard Zsofia K Stadler Michael F Berger David B Solit Michele Ly Maeve A Lowery Diana Mandelker Liying Zhang Emmett Jordan Imane El Dika Yelena Kemel Marc Ladanyi Mark E Robson Eileen M O'Reilly Ghassan K Abou-Alfa

Cancer 2020 01 3;126(9):1995-2002. Epub 2020 Feb 3.

Memorial Sloan Kettering Cancer Center, New York, New York.

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January 2020

Cancer Susceptibility Mutations in Patients With Urothelial Malignancies.

Authors:
Maria I Carlo Vignesh Ravichandran Preethi Srinavasan Chaitanya Bandlamudi Yelena Kemel Ozge Ceyhan-Birsoy Semanti Mukherjee Diana Mandelker Joshua Chaim Andrea Knezevic Satshil Rana Zarina Fnu Kelsey Breen Angela G Arnold Aliya Khurram Kaitlyn Tkachuk Catharine K Cipolla Ashley Regazzi A Ari Hakimi Hikmat Al-Ahmadie Guido Dalbagni Karen A Cadoo Michael F Walsh Min-Yuen Teo Samuel A Funt Jonathan A Coleman Bernard H Bochner Gopa Iyer David B Solit Zsofia K Stadler Liying Zhang Jonathan E Rosenberg Barry S Taylor Mark E Robson Michael F Berger Joseph Vijai Dean F Bajorin Kenneth Offit

J Clin Oncol 2020 02 3;38(5):406-414. Epub 2019 Dec 3.

Memorial Sloan Kettering Cancer Center, New York, NY.

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February 2020

Fumarate hydratase FH c.1431_1433dupAAA (p.Lys477dup) variant is not associated with cancer including renal cell carcinoma.

Authors:
Liying Zhang Michael F Walsh Sowmya Jairam Diana Mandelker Yi Zhong Yelena Kemel Ying-Bei Chen David Musheyev Ahmet Zehir Gowtham Jayakumaran Edyta Brzostowski Ozge Birsoy Ciyu Yang Yirong Li Joshua Somar Deborah DeLair Nisha Pradhan Michael F Berger Karen Cadoo Maria I Carlo Mark E Robson Zsofia K Stadler Christine A Iacobuzio-Donahue Vijai Joseph Kenneth Offit

Hum Mutat 2020 01 3;41(1):103-109. Epub 2019 Sep 3.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, New York.

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January 2020

Correction: Toward automation of germline variant curation in clinical cancer genetics.

Authors:
Vignesh Ravichandran Zarina Shameer Yelena Kemel Michael Walsh Karen Cadoo Steven Lipkin Diana Mandelker Liying Zhang Zsofia Stadler Mark Robson Kenneth Offit Joseph Vijai

Genet Med 2019 Jul;21(7):1668

Niehaus Center For Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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July 2019

Toward automation of germline variant curation in clinical cancer genetics.

Authors:
Vignesh Ravichandran Zarina Shameer Yelena Kemel Michael Walsh Karen Cadoo Steven Lipkin Diana Mandelker Liying Zhang Zsofia Stadler Mark Robson Kenneth Offit Joseph Vijai

Genet Med 2019 09 21;21(9):2116-2125. Epub 2019 Feb 21.

Niehaus Center For Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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September 2019

Ampullary cancer: Evaluation of somatic and germline genetic alterations and association with clinical outcomes.

Authors:
Winston Wong Maeve A Lowery Michael F Berger Yelena Kemel Barry Taylor Ahmet Zehir Preethi Srinivasan Chaitanya Bandlamudi Joanne Chou Marinela Capanu Anna Varghese Kenneth H Yu Christine A Iacobuzio-Donahue Jinru Shia David S Klimstra William R Jarnagin Zsofia K Stadler Eileen M O'Reilly

Cancer 2019 05 8;125(9):1441-1448. Epub 2019 Jan 8.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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May 2019

Understanding inherited risk in unselected newly diagnosed patients with endometrial cancer.

Authors:
Karen A Cadoo Diana L Mandelker Semanti Mukherjee Carolyn Stewart Deborah DeLair Vignesh Ravichandran Preethi Srinivasan Daire Hurley Yelena Kemel Angela G Arnold Margaret Sheehan Nisha Pradhan Vijai Joseph Dennis S Chi Ginger J Gardner Elizabeth L Jewell Mario M Leitao Kara Long Roche Jennifer J Mueller Yukio Sonoda Oliver Zivanovic Michael Walsh Maria I Carlo Michael F Berger David Hyman Liying Zhang Mark E Robson Kenneth Offit Carol Aghajanian Nadeem R Abu Rustum Zsofia Stadler

JCO Precis Oncol 2019 25;3. Epub 2019 Apr 25.

Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Ave., New York, NY 10065.

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April 2019

Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer.

Authors:
Alicia Latham Preethi Srinivasan Yelena Kemel Jinru Shia Chaitanya Bandlamudi Diana Mandelker Sumit Middha Jaclyn Hechtman Ahmet Zehir Marianne Dubard-Gault Christina Tran Carolyn Stewart Margaret Sheehan Alexander Penson Deborah DeLair Rona Yaeger Joseph Vijai Semanti Mukherjee Jesse Galle Mark A Dickson Yelena Janjigian Eileen M O'Reilly Neil Segal Leonard B Saltz Diane Reidy-Lagunes Anna M Varghese Dean Bajorin Maria I Carlo Karen Cadoo Michael F Walsh Martin Weiser Julio Garcia Aguilar David S Klimstra Luis A Diaz Jose Baselga Liying Zhang Marc Ladanyi David M Hyman David B Solit Mark E Robson Barry S Taylor Kenneth Offit Michael F Berger Zsofia K Stadler

J Clin Oncol 2019 02 30;37(4):286-295. Epub 2018 Oct 30.

1 Memorial Sloan Kettering Cancer Center, New York, NY.

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February 2019

Integrating somatic variant data and biomarkers for germline variant classification in cancer predisposition genes.

Authors:
Michael F Walsh Deborah I Ritter Chimene Kesserwan Dmitriy Sonkin Debyani Chakravarty Elizabeth Chao Rajarshi Ghosh Yelena Kemel Gang Wu Kristy Lee Shashikant Kulkarni Dale Hedges Diana Mandelker Ozge Ceyhan-Birsoy Minjie Luo Michael Drazer Liying Zhang Kenneth Offit Sharon E Plon

Hum Mutat 2018 11;39(11):1542-1552

Baylor College of Medicine, Houston, Texas, USA.

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November 2018

Germline mutations in children and adults with cancer.

Authors:
Marianne Dubard Gault Diana Mandelker Deborah DeLair Carolyn R Stewart Yelena Kemel Margaret R Sheehan Beth Siegel Jennifer Kennedy Vanessa Marcell Angela Arnold Hikmat Al-Ahmadie Shakeel Modak Mark Robson Neerav Shukla Stephen Roberts Joseph Vijai Sabine Topka Alex Kentsis Karen Cadoo Maria Carlo Alicia Latham Schwark Ed Reznik Renzo Dinatale Jaclyn Hechtman Ester Borras Flores Sowmaya Jairam Ciyu Yang Yirong Li Erol Can Bayraktar Ozge Ceyhan-Birsoy Liying Zhang Wendy Kohlman Joshua Schiffman Zsofia Stadler Kivanc Birsoy Andrew Kung Kenneth Offit Michael F Walsh

Cold Spring Harb Mol Case Stud 2018 08 1;4(4). Epub 2018 Aug 1.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.

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August 2018

Prevalence of Germline Mutations in Cancer Susceptibility Genes in Patients With Advanced Renal Cell Carcinoma.

Authors:
Maria I Carlo Semanti Mukherjee Diana Mandelker Joseph Vijai Yelena Kemel Liying Zhang Andrea Knezevic Sujata Patil Ozge Ceyhan-Birsoy Kuo-Cheng Huang Almedina Redzematovic Devyn T Coskey Carolyn Stewart Nisha Pradhan Angela G Arnold A Ari Hakimi Ying-Bei Chen Jonathan A Coleman David M Hyman Marc Ladanyi Karen A Cadoo Michael F Walsh Zsofia K Stadler Chung-Han Lee Darren R Feldman Martin H Voss Mark Robson Robert J Motzer Kenneth Offit

JAMA Oncol 2018 09;4(9):1228-1235

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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September 2018

Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms.

Authors:
Maeve A Lowery Winston Wong Emmet J Jordan Jonathan W Lee Yelena Kemel Joseph Vijai Diana Mandelker Ahmet Zehir Marinela Capanu Erin Salo-Mullen Angela G Arnold Kenneth H Yu Anna M Varghese David P Kelsen Robin Brenner Erica Kaufmann Vignesh Ravichandran Semanti Mukherjee Michael F Berger David M Hyman David S Klimstra Ghassan K Abou-Alfa Catherine Tjan Christina Covington Hannah Maynard Peter J Allen Gokce Askan Steven D Leach Christine A Iacobuzio-Donahue Mark E Robson Kenneth Offit Zsofia K Stadler Eileen M O'Reilly

J Natl Cancer Inst 2018 10;110(10):1067-1074

Department of Medicine.

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October 2018

Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing.

Authors:
Diana Mandelker Liying Zhang Yelena Kemel Zsofia K Stadler Vijai Joseph Ahmet Zehir Nisha Pradhan Angela Arnold Michael F Walsh Yirong Li Anoop R Balakrishnan Aijazuddin Syed Meera Prasad Khedoudja Nafa Maria I Carlo Karen A Cadoo Meg Sheehan Megan H Fleischut Erin Salo-Mullen Magan Trottier Steven M Lipkin Anne Lincoln Semanti Mukherjee Vignesh Ravichandran Roy Cambria Jesse Galle Wassim Abida Marcia E Arcila Ryma Benayed Ronak Shah Kenneth Yu Dean F Bajorin Jonathan A Coleman Steven D Leach Maeve A Lowery Julio Garcia-Aguilar Philip W Kantoff Charles L Sawyers Maura N Dickler Leonard Saltz Robert J Motzer Eileen M O'Reilly Howard I Scher Jose Baselga David S Klimstra David B Solit David M Hyman Michael F Berger Marc Ladanyi Mark E Robson Kenneth Offit

JAMA 2017 09;318(9):825-835

Memorial Sloan Kettering Cancer Center, New York, New York.

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September 2017

Genomic Characterization of Renal Medullary Carcinoma and Treatment Outcomes.

Authors:
Maria I Carlo Joshua Chaim Sujata Patil Yelena Kemel Alison M Schram Kaitlin Woo Devyn Coskey Gouri J Nanjangud Martin H Voss Darren R Feldman James J Hsieh A Ari Hakimi Ying-Bei Chen Robert J Motzer Chung-Han Lee

Clin Genitourin Cancer 2017 12 26;15(6):e987-e994. Epub 2017 Apr 26.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address:

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December 2017

Incorporating information regarding preimplantation genetic diagnosis into discussions concerning testing and risk management for BRCA1/2 mutations: a qualitative study of patient preferences.

Authors:
Karen Hurley Lisa R Rubin Allison Werner-Lin Michal Sagi Yelena Kemel Rikki Stern Aliza Phillips Ina Cholst Noah Kauff Kenneth Offit

Cancer 2012 Dec 26;118(24):6270-7. Epub 2012 Jun 26.

Department of Psychiatry and Behavioral Science, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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December 2012

BRCA1 R71K missense mutation contributes to cancer predisposition by increasing alternative transcript levels.

Authors:
Liying Zhang Lishi Chen Ruben Bacares Jeanine M Ruggeri Joshua Somar Yelena Kemel Zsofia K Stadler Kenneth Offit

Breast Cancer Res Treat 2011 Dec 24;130(3):1051-6. Epub 2011 Aug 24.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, P O Box 36, New York, NY 10065, USA.

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December 2011