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Center for Bioengineering and Tissue Regeneration, Department of Surgery, UCSF, San Francisco, CA, USA; Department of Anatomy, and Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF, San Francisco, CA, USA; UCSF Helen Diller Comprehensive Cancer Center, UCSF, San Francisco, CA, USA. Electronic address: