Yataro Daigo

Yataro Daigo

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Yataro Daigo

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Clinical significance of PD-L1-positive cancer-associated fibroblasts in pN0M0 non-small cell lung cancer.

Lung Cancer 2019 Nov 16;137:56-63. Epub 2019 Sep 16.

Department of Medical Oncology and Cancer Center, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga 520-2192, Japan; Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga 520-2192, Japan; Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.09.013DOI Listing
November 2019

Prognostic value of IL-34 in colorectal cancer patients.

Immunol Med 2019 Nov 23:1-7. Epub 2019 Nov 23.

Division of Immunobiology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.

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http://dx.doi.org/10.1080/25785826.2019.1691429DOI Listing
November 2019

Detection of neoantigen-reactive T cell clones based on the clonal expansion using next-generation sequencing of T cell receptor β complementarity-determining region 3.

J Immunol Methods 2019 Oct 23:112679. Epub 2019 Oct 23.

Department of Medical Oncology and Cancer Center, and Center for Advanced Medicine against Cancer, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga 520-2192, Japan; Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2019.112679DOI Listing
October 2019

CD26 expression is attenuated by TGF-β and SDF-1 autocrine signaling on stromal myofibroblasts in human breast cancers.

Cancer Med 2019 Jul 29;8(8):3936-3948. Epub 2019 May 29.

Department of Molecular Pathogenesis, Graduate School of Medicine, Juntendo University, Tokyo, Japan.

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http://dx.doi.org/10.1002/cam4.2249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639198PMC
July 2019

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women.

Authors:
Jason Y Y Wong Han Zhang Chao A Hsiung Kouya Shiraishi Kai Yu Keitaro Matsuo Maria Pik Wong Yun-Chul Hong Jiucun Wang Wei Jie Seow Zhaoming Wang Minsun Song Hee Nam Kim I-Shou Chang Nilanjan Chatterjee Wei Hu Chen Wu Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Adeline Seow Neil E Caporaso Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Yang Yang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Qiuyin Cai Zhihua Yin Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda H Dean Hosgood Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Michiaki Kubo Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Jianxin Shi Lei Song Xing Hua Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Fusheng Wei Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Wu-Chou Su Yu-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Li-Hsin Chien Yong-Bing Xiang Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Kyoung-Mu Lee Batel Blechter Haixin Li Yu-Tang Gao Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Laurie Burdett Meredith Yeager Amy Hutchinson Sonja I Berndt Wei Wu Herbert Pang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu C H Kang Meng Zhu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Michael Hsin Ko-Yung Sit James Ho Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho Il Yoon Chien-Chung Lin In Kyu Park Ping Xu Yuzhuo Wang Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Tzu-Yu Chen Shih-Sheng Jiang Jie Liu Taiki Yamaji Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Ying Chen Kaiyun Yang Gening Jiang Ke Fei Guoping Wu Hsien-Chin Lin Hui-Ling Chen Yao-Huei Fang Fang-Yu Tsai Wan-Shan Hsieh Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Linda Rieswijk Ann Chao Pan-Chyr Yang Xiao-Ou Shu Tangchun Wu Y L Wu Dongxin Lin Kexin Chen Baosen Zhou Yun-Chao Huang Takashi Kohno Hongbing Shen Stephen J Chanock Nathaniel Rothman Qing Lan

Genomics 2019 Jul 12. Epub 2019 Jul 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ygeno.2019.07.008DOI Listing
July 2019

Characterization of KIF11 as a novel prognostic biomarker and therapeutic target for oral cancer.

Int J Oncol 2018 Jan 31;52(1):155-165. Epub 2017 Oct 31.

Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science Hospital, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.3892/ijo.2017.4181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743338PMC
January 2018

Prognostic value of EGFR mutations in surgically resected pathological stage I lung adenocarcinoma.

Asia Pac J Clin Oncol 2017 Oct 28;13(5):e204-e211. Epub 2016 Jun 28.

Department of Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

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http://dx.doi.org/10.1111/ajco.12512DOI Listing
October 2017

The mechanism of de novo expression of programmed cell death-ligand 1 in squamous cell carcinoma of the lung.

Oncol Rep 2017 Oct 3;38(4):2189-2196. Epub 2017 Aug 3.

Department of Medical Oncology, Shiga University of Medical Science, Otsu, Shiga 520-2192, Japan.

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http://dx.doi.org/10.3892/or.2017.5876DOI Listing
October 2017

Investigation of Optimal Time for Starting Betamethasone Using Fatigue Scores and Prognostic Nutritional Index in Terminally Ill Patients With Cancer-Related Fatigue.

Am J Hosp Palliat Care 2017 Jun 16;34(5):449-455. Epub 2016 Feb 16.

1 Education and Research Center for Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan.

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http://dx.doi.org/10.1177/1049909116632487DOI Listing
June 2017

RAS-Mitogen-Activated Protein Kinase Signal Is Required for Enhanced PD-L1 Expression in Human Lung Cancers.

PLoS One 2016 15;11(11):e0166626. Epub 2016 Nov 15.

Department of Medical Oncology and Cancer Center, Shiga University of Medical Science, Otsu, Shiga, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166626PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112979PMC
June 2017

Predictive biomarkers and effectiveness of MUC1-targeted dendritic-cell-based vaccine in patients with refractory non-small cell lung cancer.

Ther Adv Med Oncol 2017 Mar 24;9(3):147-157. Epub 2016 Nov 24.

Department of Respiratory, Breast and Endocrine Surgery, Kagawa University Faculty of Medicine, Kita-gun, Kagawa, Japan.

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http://dx.doi.org/10.1177/1758834016678375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349424PMC
March 2017

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.

Authors:
Wei Jie Seow Keitaro Matsuo Chao Agnes Hsiung Kouya Shiraishi Minsun Song Hee Nam Kim Maria Pik Wong Yun-Chul Hong H Dean Hosgood Zhaoming Wang I-Shou Chang Jiu-Cun Wang Nilanjan Chatterjee Margaret Tucker Hu Wei Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Baosen Zhou Neil E Caporaso Demetrius Albanes Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Xiao-Ou Shu Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Michiaki Kubo Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Hiroshi Nokihara Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Zhihua Yin Jianxin Shi Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Tangchun Wu Fusheng Wei Jason Y Y Wong Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Victor Ho Fun Lee Wu-Chou Su Yuh-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Pan-Chyr Yang Hsien-Chih Lin Yong-Bing Xiang Adeline Seow Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Haixin Li Yu-Tang Gao Chen Wu Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Charles Lawrence Laurie Burdett Meredith Yeager Kevin B Jacobs Amy Hutchinson Sonja I Berndt Xingzhou He Wei Wu Junwen Wang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu Chang Hyun Kang Lingmin Hu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Alan Dart Loon Sihoe Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho-Il Yoon Qiuyin Cai Chien-Chung Lin In Kyu Park Ping Xu Jing Dong Christopher Kim Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen John K C Chan Minjie Chu Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Yen-Li Lo Ying-Hsiang Chen Joseph F Fraumeni Jie Liu Taiki Yamaji Yang Yang Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Gening Jiang Ke Fei Guoping Wu Li-Hsin Chien Hui-Ling Chen Yu-Chun Su Fang-Yu Tsai Yi-Song Chen Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Dongxin Lin Kexin Chen Yi-Long Wu Maria Teresa Landi Hongbing Shen Nathaniel Rothman Takashi Kohno Stephen J Chanock Qing Lan

Hum Mol Genet 2017 01;26(2):454-465

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/hmg/ddw414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856088PMC
January 2017

Cell division cycle associated 1 as a novel prognostic biomarker and therapeutic target for oral cancer.

Int J Oncol 2016 Oct 5;49(4):1385-93. Epub 2016 Aug 5.

Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.3892/ijo.2016.3649DOI Listing
October 2016

Scoring of PD-L1 expression intensity on pulmonary adenocarcinomas and the correlations with clinicopathological factors.

ESMO Open 2016 26;1(4):e000083. Epub 2016 Aug 26.

Department of Medical Oncology, Shiga University of Medical Science, Otsu, Japan; Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1136/esmoopen-2016-000083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070269PMC
August 2016

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.

Authors:
Zhaoming Wang Wei Jie Seow Kouya Shiraishi Chao A Hsiung Keitaro Matsuo Jie Liu Kexin Chen Taiki Yamji Yang Yang I-Shou Chang Chen Wu Yun-Chul Hong Laurie Burdett Kathleen Wyatt Charles C Chung Shengchao A Li Meredith Yeager Amy Hutchinson Wei Hu Neil Caporaso Maria T Landi Nilanjan Chatterjee Minsun Song Joseph F Fraumeni Takashi Kohno Jun Yokota Hideo Kunitoh Kyota Ashikawa Yukihide Momozawa Yataro Daigo Tetsuya Mitsudomi Yasushi Yatabe Toyoaki Hida Zhibin Hu Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Zhihua Yin Xuelian Li Yangwu Ren Peng Guan Jiang Chang Wen Tan Chien-Jen Chen Gee-Chen Chang Ying-Huang Tsai Wu-Chou Su Kuan-Yu Chen Ming-Shyan Huang Yuh-Min Chen Hong Zheng Haixin Li Ping Cui Huan Guo Ping Xu Li Liu Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Gening Jiang Ke Fei Jae Yong Park Yeul Hong Kim Jae Sook Sung Kyong Hwa Park Young Tae Kim Yoo Jin Jung Chang Hyun Kang In Kyu Park Hee Nam Kim Hyo-Sung Jeon Jin Eun Choi Yi Young Choi Jin Hee Kim In-Jae Oh Young-Chul Kim Sook Whan Sung Jun Suk Kim Ho-Il Yoon Sun-Seog Kweon Min-Ho Shin Adeline Seow Ying Chen Wei-Yen Lim Jianjun Liu Maria Pik Wong Victor Ho Fun Lee Bryan A Bassig Margaret Tucker Sonja I Berndt Wong-Ho Chow Bu-Tian Ji Junwen Wang Jun Xu Alan Dart Loon Sihoe James C M Ho John K C Chan Jiu-Cun Wang Daru Lu Xueying Zhao Zhenhong Zhao Junjie Wu Hongyan Chen Li Jin Fusheng Wei Guoping Wu She-Juan An Xu-Chao Zhang Jian Su Yi-Long Wu Yu-Tang Gao Yong-Bing Xiang Xingzhou He Jihua Li Wei Zheng Xiao-Ou Shu Qiuyin Cai Robert Klein William Pao Charles Lawrence H Dean Hosgood Chin-Fu Hsiao Li-Hsin Chien Ying-Hsiang Chen Chung-Hsing Chen Wen-Chang Wang Chih-Yi Chen Chih-Liang Wang Chong-Jen Yu Hui-Ling Chen Yu-Chun Su Fang-Yu Tsai Yi-Song Chen Yao-Jen Li Tsung-Ying Yang Chien-Chung Lin Pan-Chyr Yang Tangchun Wu Dongxin Lin Baosen Zhou Jinming Yu Hongbing Shen Michiaki Kubo Stephen J Chanock Nathaniel Rothman Qing Lan

Hum Mol Genet 2016 Feb 4;25(3):620-9. Epub 2016 Jan 4.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.

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http://hmg.oxfordjournals.org/content/early/2016/01/06/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731021PMC
February 2016

Regulation of iron homeostasis by the p53-ISCU pathway.

Sci Rep 2015 Nov 12;5:16497. Epub 2015 Nov 12.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/srep16497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642350PMC
November 2015

Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.

J Med Chem 2015 Feb 10;58(4):1760-75. Epub 2015 Feb 10.

Medicinal Research Laboratories, ‡Drug Developmental Research Laboratories, and §Innovative Drug Discovery Research Laboratories, Shionogi Pharmaceutical Research Center , 1-1 Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan.

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http://dx.doi.org/10.1021/jm501599uDOI Listing
February 2015

[Assessment of anticancer drug-induced adverse event].

Nihon Rinsho 2015 Feb;73 Suppl 2:75-8

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February 2015

Quantitative T cell repertoire analysis by deep cDNA sequencing of T cell receptor α and β chains using next-generation sequencing (NGS).

Oncoimmunology 2014 Dec 7;3(12):e968467. Epub 2015 Jan 7.

Committee on Clinical Pharmacology and Pharmacogenomics; The University of Chicago ; Chicago, IL USA ; Section of Hematology/Oncology; Department of Medicine; The University of Chicago ; Chicago, IL USA ; Department of Surgery; The University of Chicago ; Chicago, IL USA ; Center for Personalized Therapeutics; The University of Chicago ; Chicago, IL, USA.

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http://dx.doi.org/10.4161/21624011.2014.968467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368121PMC
December 2014

Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.

Int J Oncol 2014 Jul 6;45(1):147-56. Epub 2014 May 6.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.3892/ijo.2014.2418DOI Listing
July 2014

Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition.

Cancer Lett 2013 Aug 18;336(1):76-84. Epub 2013 Apr 18.

Laboratory of Genome Technology, Human Genome Center, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1016/j.canlet.2013.04.009DOI Listing
August 2013

RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.

Mol Cancer Res 2013 Aug 16;11(8):937-51. Epub 2013 May 16.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-12-0685-TDOI Listing
August 2013

Reevaluation of a lectin antibody ELISA kit for measuring fucosylated haptoglobin in various conditions.

Clin Chim Acta 2013 Feb 21;417:48-53. Epub 2012 Dec 21.

Department of Molecular Biochemistry and Clinical Investigation, Osaka University Graduate School of Medicine 1-7, Yamada-oka, Suita 565-0871, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00098981120058
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http://dx.doi.org/10.1016/j.cca.2012.12.014DOI Listing
February 2013

[Cancer peptide vaccine therapy based on human genomics approach].

Authors:
Yataro Daigo

Nihon Rinsho 2012 Dec;70(12):2114-7

Department of Medical Oncology, Shiga University of Medical Science.

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December 2012

Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.

Int J Oncol 2012 Oct 10;41(4):1285-96. Epub 2012 Aug 10.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.3892/ijo.2012.1589DOI Listing
October 2012

Overexpression of CDC20 predicts poor prognosis in primary non-small cell lung cancer patients.

J Surg Oncol 2012 Sep 4;106(4):423-30. Epub 2012 Apr 4.

Department of Thoracic Surgery, Sapporo Minami-Sanjo Hospital, Sapporo, Japan.

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http://dx.doi.org/10.1002/jso.23109DOI Listing
September 2012

The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.

Int J Cancer 2012 Aug 21;131(3):E179-89. Epub 2011 Dec 21.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan.

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http://dx.doi.org/10.1002/ijc.26501DOI Listing
August 2012

Critical function for nuclear envelope protein TMEM209 in human pulmonary carcinogenesis.

Cancer Res 2012 Aug 19;72(16):4110-8. Epub 2012 Jun 19.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-12-0159DOI Listing
August 2012

Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.

Cancer Sci 2012 Mar 9;103(3):577-86. Epub 2012 Jan 9.

Laboratory of Molecular Medicine, Human Genome Center, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2011.02167.xDOI Listing
March 2012

Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.

Nat Commun 2012 Feb 14;3:676. Epub 2012 Feb 14.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 1088639, Japan.

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http://dx.doi.org/10.1038/ncomms1676DOI Listing
February 2012

Overexpression of KIAA0101 predicts poor prognosis in primary lung cancer patients.

Lung Cancer 2012 Jan;75(1):110-8

Department of Thoracic Surgery, Sapporo Minami-Sanjo Hospital, Sapporo 060-0063, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2011.05.024DOI Listing
January 2012

Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.

Clin Cancer Res 2011 Dec 20;17(24):7712-22. Epub 2011 Oct 20.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://clincancerres.aacrjournals.org/content/early/2011/12/
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http://clincancerres.aacrjournals.org/content/clincanres/ear
Web Search
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-11-0619DOI Listing
December 2011

Overexpression of MAD2 predicts clinical outcome in primary lung cancer patients.

Lung Cancer 2011 Oct 4;74(1):124-31. Epub 2011 Mar 4.

Department of Thoracic Surgery, Sapporo Minami-Sanjo Hospital, S3W6 Chuo-ku, Sapporo 060-0063, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2011.01.025DOI Listing
October 2011

Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer.

Clin Cancer Res 2011 Oct 17;17(19):6272-86. Epub 2011 Aug 17.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-0060DOI Listing
October 2011

Deglycosylation and label-free quantitative LC-MALDI MS applied to efficient serum biomarker discovery of lung cancer.

Proteome Sci 2011 Apr 8;9:18. Epub 2011 Apr 8.

Laboratory for Biomarker Development, Center for Genomic Medicine, RIKEN, Tsurumiku-Suehirocho1-7-22, Yokohama, Japan.

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http://dx.doi.org/10.1186/1477-5956-9-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090313PMC
April 2011

Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.

Cancer Sci 2011 Jan 28;102(1):245-52. Epub 2010 Sep 28.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2010.01737.xDOI Listing
January 2011

C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.

Genes Chromosomes Cancer 2011 Jan;50(1):13-24

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://doi.wiley.com/10.1002/gcc.20828
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http://dx.doi.org/10.1002/gcc.20828DOI Listing
January 2011

Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis.

Cancer Res 2010 Jul 15;70(13):5337-47. Epub 2010 Jun 15.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-09-4372DOI Listing
July 2010

Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy.

Cancer Res 2010 Jul 15;70(13):5326-36. Epub 2010 Jun 15.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3879DOI Listing
July 2010

Genome-wide association study of pancreatic cancer in Japanese population.

PLoS One 2010 Jul 29;5(7):e11824. Epub 2010 Jul 29.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, Department of Medical Genome Sciences, Graduate School of Frontier Scineces, the University of Tokyo, National Cancer Center Hospital, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011824PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912284PMC
July 2010

A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.

Hum Mol Genet 2010 Jun 26;19(11):2303-12. Epub 2010 Feb 26.

Center for Genomic Medicine, Institute of Physical and Chemical Research, RIKEN, Kanagawa, Japan.

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http://dx.doi.org/10.1093/hmg/ddq091DOI Listing
June 2010

Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.

Hum Mol Genet 2010 May 18;19(10):2079-85. Epub 2010 Feb 18.

Laboratory for Statistical Analysis, Center for Genomic Medicine, Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan.

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http://dx.doi.org/10.1093/hmg/ddq080DOI Listing
May 2010

Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.

Genes Chromosomes Cancer 2010 Apr;49(4):353-67

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1002/gcc.20747DOI Listing
April 2010

Genome-wide association study of hematological and biochemical traits in a Japanese population.

Nat Genet 2010 Mar 7;42(3):210-5. Epub 2010 Feb 7.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, the University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/ng.531DOI Listing
March 2010

Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.

Clin Cancer Res 2010 Jan 22;16(1):226-39. Epub 2009 Dec 22.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-1405DOI Listing
January 2010

Overexpression of the potential kinase serine/ threonine/tyrosine kinase 1 (STYK 1) in castration-resistant prostate cancer.

Cancer Sci 2009 Nov 7;100(11):2109-14. Epub 2009 Jul 7.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://doi.wiley.com/10.1111/j.1349-7006.2009.01277.x
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http://dx.doi.org/10.1111/j.1349-7006.2009.01277.xDOI Listing
November 2009

Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.

J Hum Genet 2009 Oct 21;54(10):564-71. Epub 2009 Aug 21.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/jhg.2009.79DOI Listing
October 2009

Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.

Int J Oncol 2009 Oct;35(4):673-81

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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October 2009

Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.

Cancer Sci 2009 Aug 6;100(8):1468-78. Epub 2009 May 6.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2009.01209.xDOI Listing
August 2009

Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.

Gastroenterology 2009 Jul 8;137(1):188-98, 198.e1-2. Epub 2009 Apr 8.

Department of Molecular Biochemistry and Clinical Investigation, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1053/j.gastro.2009.04.002DOI Listing
July 2009

Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma.

Cancer Sci 2009 Jul 15;100(7):1227-33. Epub 2009 Apr 15.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2009.01165.xDOI Listing
July 2009

Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells.

Oncol Rep 2009 Feb;21(2):305-12

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.

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February 2009

Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression.

Clin Cancer Res 2009 Jan;15(1):256-66

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-08-1672DOI Listing
January 2009

Detection of novel cancer-testis antigen-specific T-cell responses in TIL, regional lymph nodes, and PBL in patients with esophageal squamous cell carcinoma.

Cancer Sci 2008 Jul 30;99(7):1448-54. Epub 2008 Apr 30.

First Department of Surgery, University of Yamanashi, 1110 Shimokato, Chuo-city, Yamanashi 409-3898, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2008.00844.xDOI Listing
July 2008

From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma.

Gen Thorac Cardiovasc Surg 2008 Feb 24;56(2):43-53. Epub 2008 Feb 24.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://link.springer.com/10.1007/s11748-007-0211-x
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http://dx.doi.org/10.1007/s11748-007-0211-xDOI Listing
February 2008

Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer.

Cancer Sci 2007 Dec 18;98(12):1902-13. Epub 2007 Sep 18.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2007.00610.xDOI Listing
December 2007

Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.

Cancer Sci 2007 Nov;98(11):1803-8

1Department of Surgery and Bioengineering, Advanced Clinical Research Center, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://doi.wiley.com/10.1111/j.1349-7006.2007.00603.x
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http://dx.doi.org/10.1111/j.1349-7006.2007.00603.xDOI Listing
November 2007

A novel method for analyzing formalin-fixed paraffin embedded (FFPE) tissue sections by mass spectrometry imaging.

Proc Jpn Acad Ser B Phys Biol Sci 2007 Nov;83(7):205-14

Life Science Laboratory, Shimadzu Corporation, Kyoto 604-8511, Japan . ; Division of Advanced Clinical Proteomics, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan .

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http://dx.doi.org/10.2183/pjab/83.205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859273PMC
November 2007

Activation of KIF4A as a prognostic biomarker and therapeutic target for lung cancer.

Clin Cancer Res 2007 Nov;13(22 Pt 1):6624-31

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-Ward, Tokyo, Japan.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-1328DOI Listing
November 2007

Comparative profiling of serum glycoproteome by sequential purification of glycoproteins and 2-nitrobenzensulfenyl (NBS) stable isotope labeling: a new approach for the novel biomarker discovery for cancer.

J Proteome Res 2007 Sep 18;6(9):3475-83. Epub 2007 Aug 18.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1021/pr070103hDOI Listing
September 2007

Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.

Cancer Res 2007 Sep 6;67(18):8544-53. Epub 2007 Sep 6.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-1307DOI Listing
September 2007

Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis.

Cancer Res 2007 May;67(9):4113-22

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-4705DOI Listing
May 2007

Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.

Mol Cancer Ther 2007 Feb;6(2):542-51

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-Ward, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0659DOI Listing
February 2007

Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.

Clin Cancer Res 2007 Jan;13(2 Pt 1):434-42

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-1297DOI Listing
January 2007