Yasuo Mori

Yasuo Mori

UNVERIFIED PROFILE

Are you Yasuo Mori?   Register this Author

Register author
Yasuo Mori

Yasuo Mori

Publications by authors named "Yasuo Mori"

Are you Yasuo Mori?   Register this Author

98Publications

1511Reads

-Profile Views

Cnnm4 deficiency suppresses Ca signaling and promotes cell proliferation in the colon epithelia.

Oncogene 2019 May 22;38(20):3962-3969. Epub 2019 Jan 22.

Department of Cellular Regulation, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, 565-0871, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-019-0682-0DOI Listing
May 2019

Impact of , and Polymorphisms on Trough Concentration to Dose Ratio of Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplantation.

Int J Mol Sci 2019 May 15;20(10). Epub 2019 May 15.

Department of Pharmacy, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20102413DOI Listing
May 2019

Safety and Seropositivity after Live Attenuated Vaccine in Adult Patients Receiving Hematopoietic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2019 Apr 6. Epub 2019 Apr 6.

Department of Medicine and Biosystemic Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2019.04.006DOI Listing
April 2019

Pathophysiological Role of TRPM2 in Age-Related Cognitive Impairment in Mice.

Neuroscience 2019 Apr 15;408:204-213. Epub 2019 Apr 15.

Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroscience.2019.04.012DOI Listing
April 2019

Involvement of TRPM2 and TRPM8 in temperature-dependent masking behavior.

Sci Rep 2019 Mar 6;9(1):3706. Epub 2019 Mar 6.

Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41598-019-40067-x
Publisher Site
http://dx.doi.org/10.1038/s41598-019-40067-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403366PMC
March 2019

TRPM2 confers susceptibility to social stress but is essential for behavioral flexibility.

Brain Res 2019 Feb 28;1704:68-77. Epub 2018 Sep 28.

Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00068993183049
Publisher Site
http://dx.doi.org/10.1016/j.brainres.2018.09.031DOI Listing
February 2019

Protective Effects of Duloxetine against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition.

J Pharmacol Exp Ther 2019 Feb 6;368(2):246-254. Epub 2018 Dec 6.

Division of Pharmacology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo, Japan (T.T., S.Y., S.S.); Department of Oral Biology, Graduate School of Dentistry, Tohoku University, Sendai, Japan (N.U., M.W.); and Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan (Y.M.)

View Article

Download full-text PDF

Source
http://jpet.aspetjournals.org/lookup/doi/10.1124/jpet.118.25
Publisher Site
http://dx.doi.org/10.1124/jpet.118.253922DOI Listing
February 2019

Successful rescue transplantation with desensitization procedure after primary graft failure due to donor-specific antibody.

Bone Marrow Transplant 2019 Feb 25. Epub 2019 Feb 25.

Department of Medicine and Biosystemic Science, Kyushu University, Graduate School of Medical Sciences, Fukuoka, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41409-019-0486-4DOI Listing
February 2019

Screening for genes that regulate the differentiation of human megakaryocytic lineage cells.

Proc Natl Acad Sci U S A 2018 10 27;115(40):E9308-E9316. Epub 2018 Aug 27.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1805434115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176640PMC
October 2018

Effect of phase-encoding direction on group analysis of resting-state functional magnetic resonance imaging.

Psychiatry Clin Neurosci 2018 Sep 2;72(9):683-691. Epub 2018 Jul 2.

Department of Psychiatry, Kyoto University, Kyoto, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pcn.12677DOI Listing
September 2018

TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines.

J Neurosci 2018 Sep 10;38(39):8484-8495. Epub 2018 Sep 10.

Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.2203-17.2018DOI Listing
September 2018

Successful treatment of Ph ALL with hematopoietic stem cell transplantation from the same HLA-haploidentical related donor of previous liver transplantation.

Leuk Lymphoma 2018 08 22;59(8):2005-2007. Epub 2017 Nov 22.

a Department of Medicine and Biosystemic Science , Kyushu University Graduate School of Medical Sciences , Fukuoka , Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10428194.2017.1403021DOI Listing
August 2018

Role of transient receptor potential melastatin 2 in surgical inflammation and dysmotility in a mouse model of postoperative ileus.

Am J Physiol Gastrointest Liver Physiol 2018 Jul 22;315(1):G104-G116. Epub 2018 Mar 22.

Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University , Kyoto , Japan.

View Article

Download full-text PDF

Source
https://www.physiology.org/doi/10.1152/ajpgi.00305.2017
Publisher Site
http://dx.doi.org/10.1152/ajpgi.00305.2017DOI Listing
July 2018

TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells.

Cancer Res 2018 May 28;78(10):2680-2690. Epub 2018 Feb 28.

Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Hebrew University Medical School, Jerusalem, Israel.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-17-3614DOI Listing
May 2018

Sensors and regulatory mechanisms of thermal physiology.

Pflugers Arch 2018 05 19;470(5):703-704. Epub 2018 Apr 19.

VIB Centre for Brain & Disease Research, Laboratory of Ion Channel Research, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00424-018-2138-8DOI Listing
May 2018

TRPM2 Channel Aggravates CNS Inflammation and Cognitive Impairment via Activation of Microglia in Chronic Cerebral Hypoperfusion.

J Neurosci 2018 Apr 9;38(14):3520-3533. Epub 2018 Mar 9.

Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, 606-8501, Japan.

View Article

Download full-text PDF

Source
http://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.2451-1
Publisher Site
http://dx.doi.org/10.1523/JNEUROSCI.2451-17.2018DOI Listing
April 2018

TRP channels in oxygen physiology: distinctive functional properties and roles of TRPA1 in O sensing.

Proc Jpn Acad Ser B Phys Biol Sci 2017 ;93(7):464-482

Laboratory of Molecular Biology, Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2183/pjab.93.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713176PMC
March 2018

DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K Channels.

Angew Chem Int Ed Engl 2018 03 1;57(10):2586-2591. Epub 2018 Feb 1.

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyotodaigakukatsura, Nishikyo-ku, Kyoto, 615-8510, Japan.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/anie.201709982
Publisher Site
http://dx.doi.org/10.1002/anie.201709982DOI Listing
March 2018

In vitro and in vivo characterization of modulation of the vacuolar cation channel TRPY1 from Saccharomyces cerevisiae.

FEBS J 2018 03 22;285(6):1146-1161. Epub 2018 Feb 22.

Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, Sendai, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/febs.14399DOI Listing
March 2018

Decreased Brain pH as a Shared Endophenotype of Psychiatric Disorders.

Neuropsychopharmacology 2018 02 4;43(3):459-468. Epub 2017 Aug 4.

Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/npp.2017.167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770757PMC
February 2018

Antiemetic efficacy and safety of granisetron or palonosetron alone and in combination with a corticosteroid for ABVD therapy-induced nausea and vomiting.

J Pharm Health Care Sci 2018 9;4. Epub 2018 Jan 9.

3Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1, Maidashi, Higashi-ku, Fukuoka City, 812-8582 Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40780-017-0097-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761115PMC
January 2018

[Reference guide for adult chronic neutropenia].

Rinsho Ketsueki 2018;59(7):845-857

Department of Hematology, Faculty of Medicine, University of Tsukuba.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11406/rinketsu.59.845DOI Listing
January 2018

Down-regulation of the Wnt/β-catenin signaling pathway by Cacnb4.

Mol Biol Cell 2017 Dec 11;28(25):3699-3708. Epub 2017 Oct 11.

L'institut du thorax, INSER, CNRS, Université de Nantes, 44000 Nantes, France

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.E17-01-0076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706996PMC
December 2017

Mast cell hyperactivity underpins the development of oxygen-induced retinopathy.

J Clin Invest 2017 Nov 9;127(11):3987-4000. Epub 2017 Oct 9.

Cooperative Major in Advanced Health Science, Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI89893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663365PMC
November 2017

Transient receptor potential melastatin 2 channels (TRPM2) mediate neonatal hypoxic-ischemic brain injury in mice.

Exp Neurol 2017 10 29;296:32-40. Epub 2017 Jun 29.

Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Department of Pharmacology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.expneurol.2017.06.023DOI Listing
October 2017

The β subunit of the voltage-gated calcium channel (Cacnb4) regulates the rate of cell proliferation in Chinese Hamster Ovary cells.

Int J Biochem Cell Biol 2017 08 3;89:57-70. Epub 2017 Jun 3.

INSERM UMR1087, LabEx Ion Channels Science and Therapeutics, Institut du Thorax, Nantes, F-44000 France; CNRS, UMR6291, Nantes, F-44000 France; Université de Nantes, Nantes, F-44000 France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biocel.2017.05.032DOI Listing
August 2017

TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy.

JCI Insight 2017 Aug 3;2(15). Epub 2017 Aug 3.

Division of Cardiocirculatory Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Aichi, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/jci.insight.93358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543921PMC
August 2017

Integrative Approach with Electrophysiological and Theoretical Methods Reveals a New Role of S4 Positively Charged Residues in PKD2L1 Channel Voltage-Sensing.

Sci Rep 2017 08 29;7(1):9760. Epub 2017 Aug 29.

Laboratory of Molecular Biology, Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, Kyoto, 615-8510, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-10357-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575081PMC
August 2017

Radiation inhibits salivary gland function by promoting STIM1 cleavage by caspase-3 and loss of SOCE through a TRPM2-dependent pathway.

Sci Signal 2017 Jun 6;10(482). Epub 2017 Jun 6.

Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scisignal.aal4064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798857PMC
June 2017

Mobilization of human immature hematopoietic progenitors through combinatory use of bortezomib and immunomodulatory drugs.

Int J Hematol 2017 Apr 21;105(4):423-432. Epub 2016 Nov 21.

Department of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12185-016-2148-2DOI Listing
April 2017

Lateralization of intrinsic frontoparietal network connectivity and symptoms in schizophrenia.

Psychiatry Res Neuroimaging 2017 Feb 16;260:23-28. Epub 2016 Dec 16.

Department of Psychiatry, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pscychresns.2016.12.007DOI Listing
February 2017

Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes.

Immunology 2017 Jan 30;150(1):64-73. Epub 2016 Sep 30.

Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Higashi-Ku, Fukuoka, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/imm.12667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341505PMC
January 2017

TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis.

Sci Rep 2016 12 19;6:39383. Epub 2016 Dec 19.

Division of Cardiocirculatory Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Aichi 444-8787, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep39383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171702PMC
December 2016

Role of transient receptor potential melastatin 2 (TRPM2) channels in visceral nociception and hypersensitivity.

Exp Neurol 2016 Nov 9;285(Pt A):41-50. Epub 2016 Sep 9.

Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Josai International University, Togane, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.expneurol.2016.09.001DOI Listing
November 2016

TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling.

Sci Rep 2016 11 11;6:37001. Epub 2016 Nov 11.

Division of Cardiocirculatory Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Okazaki, Aichi 444-8787, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep37001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105134PMC
November 2016

Mogamulizumab Treatment Prior to Allogeneic Hematopoietic Stem Cell Transplantation Induces Severe Acute Graft-versus-Host Disease.

Biol Blood Marrow Transplant 2016 09 21;22(9):1608-1614. Epub 2016 May 21.

Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan; Center for Cellular and Molecular Medicine, Kyushu University Graduate School of Medical Science, Fukuoka, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2016.05.017DOI Listing
September 2016

Inhibitory effects of Tyrphostin AG-related compounds on oxidative stress-sensitive transient receptor potential channel activation.

Eur J Pharmacol 2016 Sep 26;786:19-28. Epub 2016 May 26.

Division of Pharmacology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejphar.2016.05.033DOI Listing
September 2016

Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS.

Nat Commun 2016 09 15;7:12840. Epub 2016 Sep 15.

Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimoadachi-cho, Sakyo-ku 606-8501, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms12840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027619PMC
September 2016

Sensing of redox status by TRP channels.

Cell Calcium 2016 08 4;60(2):115-22. Epub 2016 Mar 4.

Laboratory of Molecular Biology, Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan; Laboratory of Environmental Systems Biology, Department of Technology and Ecology, Hall of Global Environmental Studies, Kyoto University, Kyoto 615-8510, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ceca.2016.02.009DOI Listing
August 2016

Deciphering Subtype-Selective Modulations in TRPA1 Biosensor Channels.

Curr Neuropharmacol 2015 ;13(2):266-78

Laboratory of Molecular Biology, Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura Campus, Nishikyoku, Kyoto 615-8510, Japan.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598439PMC
July 2016

Optical control of neuronal firing photoinduced electron transfer in donor-acceptor conjugates.

Chem Sci 2016 May 17;7(5):3331-3337. Epub 2016 Feb 17.

Institute for Integrated Cell-Material Sciences (WPI-iCeMS) , Kyoto University , Sakyo-ku , Kyoto 606-8501 , Japan . Email:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c5sc04135jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006863PMC
May 2016

Identification of human erythroid lineage-committed progenitors.

Rinsho Ketsueki 2016 05;57(5):585-91

Department of Medicine and Biosystemic Science, Kyushu University Faculty of Medicine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11406/rinketsu.57.585DOI Listing
May 2016

Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.

Amino Acids 2016 Apr 2;48(4):1045-58. Epub 2016 Jan 2.

Department of Bio-System Pharmacology, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00726-015-2158-z
Publisher Site
http://dx.doi.org/10.1007/s00726-015-2158-zDOI Listing
April 2016

Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds.

Mol Pharmacol 2016 Mar 5;89(3):348-63. Epub 2016 Jan 5.

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering (S.S., Ma.H., Y.T., H.H., Mi.H., R.R., S.K., M.X.M., Y.M.), and Department of Technology and Ecology, Hall of Global Environmental Studies (S.K., Y.M.), Kyoto University, Kyoto, Japan; Sumitomo Dainippon Pharma Co., Ltd., Osaka, Japan (Y.T., K.H., T.K., J.T., H.N., R.N.); Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Japan (A.N.); Division of Cardiocirculatory Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, Okazaki, Japan (M.N.); and Department of Physiology, School of Medicine, Fukuoka University, Fukuoka, Japan (Y.H., R.I.)

View Article

Download full-text PDF

Source
http://molpharm.aspetjournals.org/content/89/3/348.full.pdf
Web Search
http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.115.10
Publisher Site
http://dx.doi.org/10.1124/mol.115.102863DOI Listing
March 2016

Hypoxia-induced sensitisation of TRPA1 in painful dysesthesia evoked by transient hindlimb ischemia/reperfusion in mice.

Sci Rep 2016 Mar 17;6:23261. Epub 2016 Mar 17.

Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep23261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794653PMC
March 2016

Functional and Structural Divergence in Human TRPV1 Channel Subunits by Oxidative Cysteine Modification.

J Biol Chem 2016 Feb 23;291(8):4197-210. Epub 2015 Dec 23.

From the Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan, Department of Technology and Ecology, Hall of Global Environmental Studies, Kyoto University, Kyoto 615-8510, Japan

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M115.700278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759194PMC
February 2016

Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line.

Front Pharmacol 2016 9;7:19. Epub 2016 Feb 9.

Laboratory of Molecular Biology, Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto UniversityKyoto, Japan; World Premier International Research Initiative-Institute for Integrated Cell-Material Sciences, Kyoto UniversityKyoto, Japan; Laboratory of Environmental Systems Biology, Department of Technology and Ecology, Hall of Global Environmental Studies, Kyoto UniversityKyoto, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphar.2016.00019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746322PMC
February 2016

Redox-sensitive transient receptor potential channels in oxygen sensing and adaptation.

Pflugers Arch 2016 Jan 7;468(1):85-97. Epub 2015 Jul 7.

Department of Biochemistry, Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari-ku, Osaka, 537-8511, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00424-015-1716-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700073PMC
January 2016

TRPC3 amplifies B-cell receptor-induced ERK signalling via protein kinase D-dependent Rap1 activation.

Biochem J 2016 Jan 9;473(2):201-10. Epub 2015 Nov 9.

Laboratory of Molecular Biology, Department of Synthetic and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto University Katsura campus, Nishikyo-ku, Kyoto 615-8510, Japan

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20150596DOI Listing
January 2016

Oxygen physiology: sensors and ion channels.

Pflugers Arch 2016 Jan 21;468(1):1-2. Epub 2015 Nov 21.

Walther-Straub-Institute for Pharmacology and Toxicology, Ludwig-Maximilians University, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00424-015-1762-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700094PMC
January 2016

TRPM2 channels in alveolar epithelial cells mediate bleomycin-induced lung inflammation.

Free Radic Biol Med 2016 Jan 18;90:101-13. Epub 2015 Nov 18.

Division of Physiology and Pathology, Department of Pharmacology, Toxicology and Therapeutics, Showa University School of Pharmacy, Tokyo, Japan; Division of Pharmacology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University, 4-21-2 Nakano, Nakano-ku, Tokyo 164-8530, Japan; Laboratory of Pharmacology, Department of Clinical Pharmacy, Yokohama College of Pharmacy, Yokohama, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2015.11.021DOI Listing
January 2016

A Potent and Site-Selective Agonist of TRPA1.

J Am Chem Soc 2015 Dec 15;137(50):15859-64. Epub 2015 Dec 15.

Molecular Profiling Research Center for Drug Discovery, National Institute for Advanced Industrial Science and Technology , Koto-ku, Tokyo 135-0064, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jacs.5b10162DOI Listing
December 2015

Sensitization of H2O2-induced TRPM2 activation and subsequent interleukin-8 (CXCL8) production by intracellular Fe(2+) in human monocytic U937 cells.

Int J Biochem Cell Biol 2015 Nov 16;68:119-27. Epub 2015 Sep 16.

Laboratory of Pharmacology, Department of Clinical Pharmacy, Yokohama College of Pharmacy, Yokohama 245-0066, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biocel.2015.09.005DOI Listing
November 2015

The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment.

J Neurosci 2015 Nov;35(45):15157-69

Molecular Medicine, Robarts Research Institute, Department of Physiology and Pharmacology, Schulich School of Medicine, and Department of Pharmacology and Therapeutics, College of Medicine, University of Manitoba, Winnipeg, Manitoba R3E 0T6, Canada, Neuroscience Research Group, Kleysen Institute for Advanced Medicine, University of Manitoba, Winnipeg, Manitoba R3E 3J7, Canada, and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.4081-14.2015DOI Listing
November 2015

Rab3 interacting molecule 3 mutations associated with autism alter regulation of voltage-dependent Ca²⁺ channels.

Cell Calcium 2015 Sep 23;58(3):296-306. Epub 2015 Jun 23.

Laboratory of Molecular Biology, Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan; Laboratory of Environmental Systems Biology, Department of Technology and Ecology, Hall of Global Environmental Studies, Kyoto University, Kyoto 615-8510, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ceca.2015.06.007DOI Listing
September 2015

Thermosensitive Ion Channel Activation in Single Neuronal Cells by Using Surface-Engineered Plasmonic Nanoparticles.

Angew Chem Int Ed Engl 2015 Sep 6;54(40):11725-9. Epub 2015 Aug 6.

Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Sakyo-ku, Kyoto 606-8501 (Japan).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201505534DOI Listing
September 2015

Validating subcellular thermal changes revealed by fluorescent thermosensors.

Nat Methods 2015 Sep;12(9):801-2

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nmeth.3548DOI Listing
September 2015

Prospective isolation of human erythroid lineage-committed progenitors.

Proc Natl Acad Sci U S A 2015 Aug 20;112(31):9638-43. Epub 2015 Jul 20.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Biology and Medicine at Stanford University, Stanford, CA 94305

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1512076112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534255PMC
August 2015

Transient receptor potential channel M2 contributes to neointimal hyperplasia in vascular walls.

Biochim Biophys Acta 2015 Jul 6;1852(7):1360-71. Epub 2015 Apr 6.

Li Ka Shing Institute of Health Science and School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China; Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbadis.2015.03.014DOI Listing
July 2015

Comprehensive behavioral analysis of voltage-gated calcium channel beta-anchoring and -regulatory protein knockout mice.

Front Behav Neurosci 2015 16;9:141. Epub 2015 Jun 16.

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University Kyoto, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnbeh.2015.00141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468383PMC
July 2015

Compromised maturation of GABAergic inhibition underlies abnormal network activity in the hippocampus of epileptic Ca2+ channel mutant mice, tottering.

Pflugers Arch 2015 Apr 20;467(4):737-52. Epub 2014 Jun 20.

Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00424-014-1555-6DOI Listing
April 2015

Involvement of TRPM2 in a wide range of inflammatory and neuropathic pain mouse models.

J Pharmacol Sci 2015 Mar 18;127(3):237-43. Epub 2015 Feb 18.

Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jphs.2014.10.003DOI Listing
March 2015

Fluorescent sensors reveal subcellular thermal changes.

Curr Opin Biotechnol 2015 Feb 29;31:57-64. Epub 2014 Aug 29.

World Premier International Research Initiative-Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto 606-8501, Japan; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan; Department of Technology and Ecology, Hall of Global Environmental Studies, Kyoto University, Kyoto 615-8510, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.copbio.2014.07.013DOI Listing
February 2015

[Bone and Calcium Research Update 2015. Basic mechanisms underlying calcium signaling and their biological potentiality].

Clin Calcium 2015 Jan;25(1):47-58

Laboratory of Environmental Systems Biology, Graduate School of Environmental Studies and Laboratory of Molecular Biology, Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering Kyoto University, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/CliCa15014758DOI Listing
January 2015

TRPs as chemosensors (ROS, RNS, RCS, gasotransmitters).

Handb Exp Pharmacol 2014 ;223:767-94

Division of Physiology and Pathology, Department of Pharmacology, Toxicology and Therapeutics, Showa University School of Pharmacy, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-319-05161-1_3DOI Listing
November 2014

Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca(2+) entry.

Eur J Pharmacol 2014 Nov 30;742:22-30. Epub 2014 Aug 30.

Division of Physiology and Pathology, Department of Pharmacology, Toxicology and Therapeutics, Showa University School of Pharmacy, Tokyo 142-8555, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejphar.2014.08.023DOI Listing
November 2014

Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure.

Cardiovasc Res 2014 Oct 5;104(1):183-93. Epub 2014 Aug 5.

Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/cvr/cvu185DOI Listing
October 2014

15-deoxy-?(12,14)-prostaglandin J2 as a potential TRPV1-dependent atopic dermatitis enhancer.

Free Radic Biol Med 2014 Oct 10;75 Suppl 1:S49. Epub 2014 Dec 10.

Nagoya University (Graduate School of Bioagricultural Sciences), Division of Biofunctional Chemistry, Japan;

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08915849140131
Publisher Site
http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.815DOI Listing
October 2014

TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P₂.

Nat Commun 2014 Sep 26;5:4994. Epub 2014 Sep 26.

1] Laboratory of Membrane and Cytoskeleton Dynamics, Institute of Molecular and Cellular Biosciences, University of Tokyo, Tokyo 113-0032, Japan [2] Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, 630-0192, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms5994DOI Listing
September 2014

Transient receptor potential melastatin 2 protects mice against polymicrobial sepsis by enhancing bacterial clearance.

Anesthesiology 2014 Aug;121(2):336-51

From the Department of Anaesthesia, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China (X.Q., K.Z., C.L., J.H., X.F.); and Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan (T.N., Y.M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ALN.0000000000000275DOI Listing
August 2014

Involvement of TRPM2 and L-type Ca²⁺ channels in Ca²⁺ entry and cell death induced by hydrogen peroxide in rat β-cell line RIN-5F.

J Toxicol Sci 2014 Apr;39(2):199-209

Department of Pharmacology, Toxicology and Therapeutics, Division of Physiology and Pathology, Showa University School of Pharmacy.

View Article

Download full-text PDF

Source
April 2014

TRPM2 contributes to LPS/IFNγ-induced production of nitric oxide via the p38/JNK pathway in microglia.

Biochem Biophys Res Commun 2014 Feb 22;444(2):212-7. Epub 2014 Jan 22.

Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2014.01.022DOI Listing
February 2014