Yasunobu Yoshikai

Yasunobu Yoshikai

UNVERIFIED PROFILE

Are you Yasunobu Yoshikai?   Register this Author

Register author
Yasunobu Yoshikai

Yasunobu Yoshikai

Publications by authors named "Yasunobu Yoshikai"

Are you Yasunobu Yoshikai?   Register this Author

100Publications

-Reads

Interleukin-21 Induces Short-Lived Effector CD8 T Cells but Does Not Inhibit Their Exhaustion after Mycobacterium bovis BCG Infection in Mice.

Infect Immun 2018 Aug 23;86(8). Epub 2018 Jul 23.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

View Article
August 2018

Association of Decreased Percentage of Vδ2Vγ9 γδ T Cells With Disease Severity in Multiple Sclerosis.

Front Immunol 2018 10;9:748. Epub 2018 Apr 10.

Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

View Article
April 2018

Glucocorticoids Drive Diurnal Oscillations in T Cell Distribution and Responses by Inducing Interleukin-7 Receptor and CXCR4.

Immunity 2018 02 27;48(2):286-298.e6. Epub 2018 Jan 27.

Laboratory of Immune Regulation, Department of Virus Research, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. Electronic address:

View Article
February 2018

Serum IgG ACPA-IgM RF immune complexes were detected in rheumatoid arthritis patients positive for IgM ACPA.

Clin Exp Rheumatol 2018 Jul-Aug;36(4):612-618. Epub 2018 Feb 14.

Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan.

View Article
February 2018

In vivo blockade of T cell development reveals alternative pathways for generation of intraepithelial lymphocytes in mice.

Immunol Lett 2017 11 27;191:40-46. Epub 2017 Sep 27.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.

View Article
November 2017

CD5NK1.1 γδ T Cells that Develop in a Bcl11b-Independent Manner Participate in Early Protection against Infection.

Cell Rep 2017 Oct;21(5):1191-1202

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan. Electronic address:

View Article
October 2017

Subtyping of Type 1 Diabetes as Classified by Anti-GAD Antibody, IgE Levels, and Tyrosine kinase 2 (TYK2) Promoter Variant in the Japanese.

EBioMedicine 2017 Sep 12;23:46-51. Epub 2017 Aug 12.

Department of Medical Science and Technology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan; Department of Hepatology, Diabetes and Endocrinology, Faculty of Medicine, Saga University, 5-1-1, Nabeshima, Saga, Japan. Electronic address:

View Article
September 2017

Two Types of Interleukin 17A-Producing γδ T Cells in Protection Against Pulmonary Infection With Klebsiella pneumoniae.

J Infect Dis 2016 Dec 20;214(11):1752-1761. Epub 2016 Sep 20.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka.

View Article
December 2016

C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection.

Immunity 2016 12 22;45(6):1245-1257. Epub 2016 Nov 22.

Division of Molecular Immunology, Research Center for Infectious Diseases, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan; Division of Molecular Immunology, Medical Mycology Research Center, Chiba University, Chiba 260-8673, Japan. Electronic address:

View Article
December 2016

IL-21 inhibits IL-17A-producing γδ T-cell response after infection with Bacillus Calmette-Guérin via induction of apoptosis.

Innate Immun 2016 11 22;22(8):588-597. Epub 2016 Sep 22.

1 Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
November 2016

Interleukin-21 signaling in B cells, but not in T cells, is indispensable for the development of collagen-induced arthritis in mice.

Arthritis Res Ther 2016 08 17;18:188. Epub 2016 Aug 17.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.

View Article
August 2016

IL-21/IL-21R signaling suppresses intestinal inflammation induced by DSS through regulation of Th responses in lamina propria in mice.

Sci Rep 2016 08 22;6:31881. Epub 2016 Aug 22.

Division of Host Defense, Center for Prevention of Infectious Disease, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
August 2016

Recombinant Mycobacterium bovis bacillus Calmette-Guérin expressing Ag85B-IL-7 fusion protein enhances IL-17A-producing innate γδ T cells.

Vaccine 2016 05 11;34(22):2490-5. Epub 2016 Apr 11.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, 3-1-1, Maidaishi, Higashi-ku, Fukuoka 812-8582, Japan. Electronic address:

View Article
May 2016

Requirement of CD30 expression on CD4 T cells in the pathogenesis of experimental autoimmune encephalomyelitis.

J Neuroimmunol 2016 Feb 11;291:39-45. Epub 2015 Dec 11.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan. Electronic address:

View Article
February 2016

An Enhancer of the IL-7 Receptor α-Chain Locus Controls IL-7 Receptor Expression and Maintenance of Peripheral T Cells.

J Immunol 2015 Oct 2;195(7):3129-38. Epub 2015 Sep 2.

Laboratory of Biological Protection, Department of Biological Responses, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan;

View Article
October 2015

IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2(+)Vγ6(+)γδ T cells.

Nat Commun 2015 Jun 25;6:7464. Epub 2015 Jun 25.

1] Laboratory of Molecular Pathogenesis, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan [2] Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0032, Japan [3] Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency, Saitama 332-0012, Japan [4] Division of Experimental Animal Immunology, Center for Animal Disease Models, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba 278-0022, Japan.

View Article
June 2015

Dermal Vγ4(+) γδ T cells possess a migratory potency to the draining lymph nodes and modulate CD8(+) T-cell activity through TNF-α production.

J Invest Dermatol 2015 Apr 10;135(4):1007-1015. Epub 2014 Dec 10.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; PRESTO, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan. Electronic address:

View Article
April 2015

Scavenger receptor for lipoteichoic acid is involved in the potent ability of Lactobacillus plantarum strain L-137 to stimulate production of interleukin-12p40.

Int Immunopharmacol 2015 Apr 16;25(2):321-31. Epub 2015 Feb 16.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan. Electronic address:

View Article
April 2015

Renal cancer treatment with recipient lymphocyte infusion enhanced the antitumor effect of nonmyeloablative allogeneic stem cell transplantation.

Transpl Immunol 2015 Mar 16;32(2):131-9. Epub 2014 Dec 16.

Division of Host Defense, Research Center for Prevention of Infectious Disease, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
March 2015

CD30 ligand is a new therapeutic target for central nervous system autoimmunity.

J Autoimmun 2015 Feb 19;57:14-23. Epub 2014 Dec 19.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan. Electronic address:

View Article
February 2015

A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice.

J Immunol 2015 Jan 26;194(1):243-51. Epub 2014 Nov 26.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan;

View Article
January 2015

IFN-γ-producing and IL-17-producing γδ T cells differentiate at distinct developmental stages in murine fetal thymus.

J Immunol 2014 Mar 31;192(5):2210-8. Epub 2014 Jan 31.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.

View Article
March 2014

Oral administration of bovine milk from cows hyperimmunized with intestinal bacterin stimulates lamina propria T lymphocytes to produce Th1-biased cytokines in mice.

Int J Mol Sci 2014 Mar 28;15(4):5458-71. Epub 2014 Mar 28.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

View Article
March 2014

Identification of independent susceptible and protective HLA alleles in Japanese autoimmune thyroid disease and their epistasis.

J Clin Endocrinol Metab 2014 Feb 27;99(2):E379-83. Epub 2013 Nov 27.

Institute for Advanced Study (S.U., D.O., T.S.), Division of Genome Analysis (K.Y.), Medical Institute of Bioregulation, Department of Medicine and Clinical Science (K.O.), Graduate School of Medicine, and Division of Host Defense (H.Y., A.O., Y.Y.), Medical Institute of Bioregulation, Kyushu University, Kyushu University, Higashi-ku, Fukuoka 812-8582, Japan; Ito Hospital (J.Y.N., Y.K., K.S., K.I.), Shibuya-ku, Tokyo 150-8308, Japan; Department of Diabetes and Metabolic Medicine (M.N., K.I.), National Center for Global Health and Medicine, Shinjuku-ku, Tokyo 16-8655, Japan; Department of Laboratory (K.K.), Japanese Red Cross Tokyo Blood Center, Koto-ku, Tokyo 135-8639, Japan; and Department of Immunogenetics (Y.N.), Graduate School of Medical Sciences, Kumamoto University, Chuo-ku, Kumamoto 860-8556, Japan.

View Article
February 2014

A C-type lectin receptor pathway is responsible for the pathogenesis of acute cyclophosphamide-induced cystitis in mice.

Microbiol Immunol 2013 Dec;57(12):833-41

Division of Host Defense, Medical Institute of Bioregulation; Department of Urology, Graduate School of Medical Science, Kyushu University, Fukuoka.

View Article
December 2013

Type I interferon limits influenza virus-induced acute lung injury by regulation of excessive inflammation in mice.

Antiviral Res 2013 Sep 28;99(3):230-7. Epub 2013 May 28.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

View Article
September 2013

Positive selection of self-antigen-specific CD8+ T cells by hematopoietic cells.

Eur J Immunol 2013 Aug 22;43(8):2033-42. Epub 2013 May 22.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
August 2013

CD4 T cell-intrinsic IL-2 signaling differentially affects Th1 and Th17 development.

J Leukoc Biol 2013 Aug 28;94(2):271-9. Epub 2013 May 28.

Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka 812-8582, Japan.

View Article
August 2013

C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor.

Immunity 2013 May 18;38(5):1050-62. Epub 2013 Apr 18.

Division of Molecular Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.

View Article
May 2013

Naturally occurring PD-1+ memory phenotype CD8 T cells belong to nonconventional CD8 T cells and are cyclophosphamide-sensitive regulatory T cells.

J Immunol 2013 Feb 9;190(4):1560-6. Epub 2013 Jan 9.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.

View Article
February 2013

CD4 T cell-mediated masking effects of the immunogenicity of tumor-associated antigens are qualitatively and quantitatively different depending on the individual antigens.

Fukuoka Igaku Zasshi 2013 Jan;104(1):1-14

Division of Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

View Article
January 2013

Fas-deficient fully allogeneic dendritic cells administered via an intratumoral injection route show efficient antitumor effects in murine models.

Fukuoka Igaku Zasshi 2013 Jan;104(1):15-26

Division of Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

View Article
January 2013

Daily intake of heat-killed Lactobacillus plantarum L-137 enhances type I interferon production in healthy humans and pigs.

Immunopharmacol Immunotoxicol 2012 Dec 2;34(6):937-43. Epub 2012 Apr 2.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Higashi-ku, Fukuoka, Japan.

View Article
December 2012

CD30 ligand/CD30 interaction is involved in pathogenesis of inflammatory bowel disease.

Dig Dis Sci 2012 Aug 27;57(8):2031-7. Epub 2012 Mar 27.

Department of Advanced Molecular and Cell Therapy, Kyushu University Hospital, Fukuoka, Japan.

View Article
August 2012

A reduction of recipient regulatory T cells by cyclophosphamide contributes to an anti-tumor effect of nonmyeloablative allogeneic stem cell transplantation in mice.

Int J Cancer 2012 Jan 25;130(2):365-76. Epub 2011 Apr 25.

Division of Host Defense, Research Center for Prevention of Infectious Disease, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Kyushu, Japan.

View Article
January 2012

Protective role of naturally occurring interleukin-17A-producing γδ T cells in the lung at the early stage of systemic candidiasis in mice.

Infect Immun 2011 Nov 29;79(11):4503-10. Epub 2011 Aug 29.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

View Article
November 2011

The central role of CD30L/CD30 interactions in allergic rhinitis pathogenesis in mice.

Eur J Immunol 2011 Oct 30;41(10):2947-54. Epub 2011 Aug 30.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
October 2011

Innate memory phenotype CD4+ T cells play a role in early protection against infection by Listeria monocytogenes in a CD30L-dependent manner.

Microbiol Immunol 2011 Sep;55(9):645-56

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
September 2011

Preferential accumulation of activated Th1 cells not only in rheumatoid arthritis but also in osteoarthritis joints.

J Rheumatol 2011 Aug 1;38(8):1569-75. Epub 2011 May 1.

Division of Host Defence, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
August 2011

Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells.

Blood 2011 Jul 23;118(3):586-93. Epub 2011 May 23.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Higashi-ku, Fukuoka, Japan.

View Article
July 2011

Functional involvement of dual specificity phosphatase 16 (DUSP16), a c-Jun N-terminal kinase-specific phosphatase, in the regulation of T helper cell differentiation.

J Biol Chem 2011 Jul 25;286(28):24896-905. Epub 2011 May 25.

Department of Oral Biochemistry, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Japan.

View Article
July 2011

[Studies of T cells for better understanding of immunity and allergy].

Nihon Jibiinkoka Gakkai Kaiho 2011 Jun;114(6):539-46

View Article
June 2011

Provision of continuous maturation signaling to dendritic cells by RIG-I-stimulating cytosolic RNA synthesis of Sendai virus.

J Immunol 2011 Feb 27;186(3):1828-39. Epub 2010 Dec 27.

Division of Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

View Article
February 2011

Mechanism of synergistic antitumor effect of sorafenib and interferon-α on treatment of renal cell carcinoma.

J Urol 2010 Dec 28;184(6):2549-56. Epub 2010 Oct 28.

Department of Urology, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan.

View Article
December 2010

CD30 ligand is a target for a novel biological therapy against colitis associated with Th17 responses.

J Immunol 2010 Dec 10;185(12):7671-80. Epub 2010 Nov 10.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
December 2010

CD30 ligand/CD30 plays a critical role in Th17 differentiation in mice.

J Immunol 2010 Aug 16;185(4):2222-30. Epub 2010 Jul 16.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
August 2010

Interleukin-15 is critical in the pathogenesis of influenza a virus-induced acute lung injury.

J Virol 2010 Jun 24;84(11):5574-82. Epub 2010 Mar 24.

Division of Host Defence, Research Center for Prevention of Infectious Diseases, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
June 2010

Lipoteichoic acids on Lactobacillus plantarum cell surfaces correlate with induction of interleukin-12p40 production.

Microbiol Immunol 2010 Mar;54(3):143-51

Food Science Research Center, House Wellness Foods Corporation, 3-20 Imoji, Itami 664-0011, Japan.

View Article
March 2010

Dual specificity phosphatase16 is a negative regulator of c-Jun NH2-terminal kinase activity in T cells.

Microbiol Immunol 2010 Feb;54(2):105-11

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Higashi-ku, Fukuoka, Japan.

View Article
February 2010

Susceptibility of human T-cell leukemia virus type I-infected cells to humanized anti-CD30 monoclonal antibodies in vitro and in vivo.

Cancer Sci 2010 Jan 8;101(1):224-30. Epub 2009 Sep 8.

Division of Host Defense, Research Center for Prevention of Infectious Diseases, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
January 2010

Oral administration of xanthan gum enhances antitumor activity through Toll-like receptor 4.

Int Immunopharmacol 2009 Dec 27;9(13-14):1562-7. Epub 2009 Sep 27.

Division of Host Defense, Research Center for Prevention of Infectious Disease, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.

View Article
December 2009

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle.

J Exp Med 2009 Dec 14;206(13):2879-88. Epub 2009 Dec 14.

Division of Molecular Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.

View Article
December 2009

Protective role of Fas-FasL signaling in lethal infection with herpes simplex virus type 2 in mice.

J Virol 2009 Nov 9;83(22):11777-83. Epub 2009 Sep 9.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
November 2009

Oral administration of heat-killed Lactobacillus plantarum L-137 enhances protection against influenza virus infection by stimulation of type I interferon production in mice.

Int Immunopharmacol 2009 Aug 3;9(9):1122-5. Epub 2009 May 3.

Research Center for Prevention of Infectious Diseases, Medical Institute of Bioregulation, Kyushu University, Maidashi, Higashi-ku, Fukuoka, Japan.

View Article
August 2009

IL-15 protects antigen-specific CD8+ T cell contraction after Mycobacterium bovis bacillus Calmette-Guérin infection.

J Leukoc Biol 2009 Jul 23;86(1):187-94. Epub 2009 Apr 23.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Higashi-ku, Fukuoka, Japan.

View Article
July 2009

IL-15 is critical for the maintenance and innate functions of self-specific CD8(+) T cells.

Eur J Immunol 2009 Jul;39(7):1784-93

Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
July 2009

[Immunological protection against Mycobacterium tuberculosis infection].

Tanpakushitsu Kakusan Koso 2009 Jun;54(8 Suppl):1014-9

View Article
June 2009

Donor CD4 T cells are critical in allogeneic stem cell transplantation against murine solid tumor.

Cancer Res 2009 Jun 2;69(12):5151-8. Epub 2009 Jun 2.

Division of Host Defense, Research Center for Prevention of Infectious Disease, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
June 2009

Allogeneic cell therapy from immunized donors with tumor antigen peptide enhances the antitumor effect after cyclophosphamide-using non-myeloablative allogeneic hematopoietic cell transplantation.

Cancer Sci 2009 Jan 24;100(1):138-43. Epub 2008 Nov 24.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, and Center for Cellular and Molecular Medicine, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

View Article
January 2009

Oncogenesis by retroviruses: old and new paradigms.

Rev Med Virol 2008 Nov-Dec;18(6):387-405

Division of Host Defense, Research Center for Prevention of Infectious Diseases, Medical Institute of Bioregulation, Kyushu University, Higashi-ku, Fukuoka, Japan.

View Article
December 2008

Lipocalin 2-dependent inhibition of mycobacterial growth in alveolar epithelium.

J Immunol 2008 Dec;181(12):8521-7

Department of Microbiology and Immunology, Laboratory of Immune Regulation, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.

View Article
December 2008

Identification of CD25+ gamma delta T cells as fetal thymus-derived naturally occurring IL-17 producers.

J Immunol 2008 Nov;181(9):5940-7

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
November 2008

OX40 costimulatory signals potentiate the memory commitment of effector CD8+ T cells.

J Immunol 2008 Nov;181(9):5990-6001

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan.

View Article
November 2008

A novel role of CD30L/CD30 signaling by T-T cell interaction in Th1 response against mycobacterial infection.

J Immunol 2008 Nov;181(9):6316-27

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
November 2008

Role of the cytokine profiles produced by invariant natural killer T cells in the initial phase of cyclophosphamide-induced tolerance.

Transplantation 2008 Nov;86(9):1301-10

Department of Cardiovascular Surgery, Faculty of Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan.

View Article
November 2008

Immunological protection against mycobacterium tuberculosis infection.

Crit Rev Immunol 2006 ;26(6):515-26

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.

View Article
August 2008

A critical role of CD30 ligand/CD30 in controlling inflammatory bowel diseases in mice.

Gastroenterology 2008 Feb 4;134(2):447-58. Epub 2007 Nov 4.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
February 2008

A regulatory role of interleukin 15 in wound healing and mucosal infection in mice.

J Leukoc Biol 2008 Jan 28;83(1):165-72. Epub 2007 Sep 28.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

View Article
January 2008

Vdelta1+ T cells are crucial for repertoire formation of gammadelta T cells in the lung.

Biochem Biophys Res Commun 2008 Jan 5;365(2):246-51. Epub 2007 Nov 5.

Department of Immunology and Parasitology, Institute of Health Biosciences, The University of Tokushima School of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.

View Article
January 2008

[New molecular mechanisms of virus-mediated carcinogenesis: oncogenic transformation of cells by retroviral structural protein Envelope].

Uirusu 2007 Dec;57(2):159-70

Division of Host Defense, Research Center for Prevention of Infectious Diseases, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

View Article
December 2007

Ceramide inhibits LPS-induced production of IL-5, IL-10, and IL-13 from mast cells.

J Cell Physiol 2007 Oct;213(1):126-36

Division of Host Defense, Center for Neural Disease and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan.

View Article
October 2007

IL-15 exacerbates collagen-induced arthritis with an enhanced CD4+ T cell response to produce IL-17.

Eur J Immunol 2007 Oct;37(10):2744-52

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

View Article
October 2007

In vivo treatment with a nonapeptide thymic hormone, facteur thymique serique (FTS), ameliorates chronic colitis induced by dextran sulphate sodium in mice.

Int Immunopharmacol 2007 Jul 28;7(7):928-36. Epub 2007 Mar 28.

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

View Article
July 2007

Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production.

J Immunol 2007 Apr;178(7):4466-72

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

View Article
April 2007

Tyk2 signaling in host environment plays an important role in contraction of antigen-specific CD8+ T cells following a microbial infection.

J Immunol 2007 Apr;178(7):4482-8

Division of Host Defense and Digital Medicine Initiative, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Japan.

View Article
April 2007

H2-M3-restricted CD8+ T cells induced by peptide-pulsed dendritic cells confer protection against Mycobacterium tuberculosis.

J Immunol 2007 Mar;178(6):3806-13

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.

View Article
March 2007

[Roles of natural memory lymphocytes in host defense mechanisms].

Nihon Rinsho 2007 Feb;65 Suppl 2 Pt. 1:109-12

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University.

View Article
February 2007

Enforced expression of Bcl-2 partially restores cell numbers but not functions of TCRgammadelta intestinal intraepithelial T lymphocytes in IL-15-deficient mice.

J Immunol 2007 Jan;178(2):757-64

Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

View Article
January 2007

Effects of cyclosporin A on the activation of natural killer T cells induced by alpha-galactosylceramide.

Transplantation 2007 Jan;83(2):184-92

Department of Cardiovascular Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

View Article
January 2007

Daily intake of heat-killed Lactobacillus plantarum L-137 augments acquired immunity in healthy adults.

J Nutr 2006 Dec;136(12):3069-73

Research and Development Department, House Wellness Foods, Itami 664-0011, Japan.

View Article
December 2006

Regulatory roles of NKT cells in the induction and maintenance of cyclophosphamide-induced tolerance.

J Immunol 2006 Dec;177(12):8400-9

Department of Cardiovascular Surgery, Department of Pathology, Greaduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

View Article
December 2006