Yassir Younis

Yassir Younis

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Yassir Younis

Yassir Younis

Publications by authors named "Yassir Younis"

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14Publications

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Synthesis and structure-activity-relationship studies of thiazolidinediones as antiplasmodial inhibitors of the Plasmodium falciparum cysteine protease falcipain-2.

Eur J Med Chem 2015 Jan 2;90:507-18. Epub 2014 Dec 2.

Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch 7701, South Africa; South African Medical Research Council, Drug Discovery and Development Unit, University of Cape Town, Rondebosch 7701, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.11.061DOI Listing
January 2015

Cell-based medicinal chemistry optimization of high throughput screening hits for orally active antimalarials. Part 2: hits from SoftFocus kinase and other libraries.

J Med Chem 2013 Oct 30;56(20):7750-4. Epub 2013 Aug 30.

Department of Chemistry, University of Cape Town , Rondebosch 7701, South Africa.

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http://dx.doi.org/10.1021/jm400279yDOI Listing
October 2013

Novel orally active antimalarial thiazoles.

J Med Chem 2011 Nov 11;54(21):7713-9. Epub 2011 Oct 11.

Department of Chemistry, University of Cape Town , Rondebosch 7701, South Africa.

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http://dx.doi.org/10.1021/jm201108kDOI Listing
November 2011

[d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase.

Bioorg Med Chem 2010 Jul 11;18(13):4661-73. Epub 2010 May 11.

Department of Chemistry, University of Cape Town, Rondebosch 7701, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.bmc.2010.05.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964380PMC
July 2010