Yaoyong Li

Yaoyong Li

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Yaoyong Li

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Geno2proteo, a Tool for Batch Retrieval of DNA and Protein Sequences from Any Genomic or Protein Regions.

Authors:
Yaoyong Li Elisa Aguilar-Martinez Andrew D Sharrocks

J Integr Bioinform 2019 Jul 13;16(3). Epub 2019 Jul 13.

School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1515/jib-2018-0090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798850PMC
July 2019

Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia.

Authors:
Alba Maiques-Diaz Gary J Spencer James T Lynch Filippo Ciceri Emma L Williams Fabio M R Amaral Daniel H Wiseman William J Harris Yaoyong Li Sudhakar Sahoo James R Hitchin Daniel P Mould Emma E Fairweather Bohdan Waszkowycz Allan M Jordan Duncan L Smith Tim C P Somervaille

Cell Rep 2018 03;22(13):3641-3659

Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester Cancer Research Centre Building, 555 Wilmslow Road, Manchester M20 4GJ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896174PMC
March 2018

EINCR1 is an EGF inducible lincRNA overexpressed in lung adenocarcinomas.

Authors:
Karol Nowicki-Osuch Yaoyong Li Mairi Challinor David T Gerrard Neil A Hanley Andrew D Sharrocks

PLoS One 2017 21;12(7):e0181902. Epub 2017 Jul 21.

School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181902PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521836PMC
September 2017

Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma.

Authors:
Edward Britton Connor Rogerson Shaveta Mehta Yaoyong Li Xiaodun Li Rebecca C Fitzgerald Yeng S Ang Andrew D Sharrocks

PLoS Genet 2017 Aug 31;13(8):e1006879. Epub 2017 Aug 31.

School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

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http://dx.plos.org/10.1371/journal.pgen.1006879
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http://dx.doi.org/10.1371/journal.pgen.1006879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578490PMC
August 2017

Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer.

Authors:
Louise Carter Dominic G Rothwell Barbara Mesquita Christopher Smowton Hui Sun Leong Fabiola Fernandez-Gutierrez Yaoyong Li Deborah J Burt Jenny Antonello Christopher J Morrow Cassandra L Hodgkinson Karen Morris Lynsey Priest Mathew Carter Crispin Miller Andrew Hughes Fiona Blackhall Caroline Dive Ged Brady

Nat Med 2017 01 21;23(1):114-119. Epub 2016 Nov 21.

Clinical and Experimental Pharmacology Group, CRUK Manchester Institute, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1038/nm.4239DOI Listing
January 2017

Jun-Mediated Changes in Cell Adhesion Contribute to Mouse Embryonic Stem Cell Exit from Ground State Pluripotency.

Authors:
Giulia Veluscek Yaoyong Li Shen-Hsi Yang Andrew D Sharrocks

Stem Cells 2016 05 13;34(5):1213-24. Epub 2016 Feb 13.

Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1002/stem.2294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864893PMC
May 2016

Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample.

Authors:
Dominic G Rothwell Nigel Smith Daniel Morris Hui Sun Leong Yaoyong Li Antoine Hollebecque Mahmood Ayub Louise Carter Jenny Antonello Lynsey Franklin Crispin Miller Fiona Blackhall Caroline Dive Ged Brady

Mol Oncol 2016 Apr 19;10(4):566-74. Epub 2015 Nov 19.

Nucleic Acid Biomarker Laboratory, Clinical Experimental Pharmacology Group, CR-UK Manchester Institute, University of Manchester, M20 4BX, UK.

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http://dx.doi.org/10.1016/j.molonc.2015.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834815PMC
April 2016

Epithelial and stromal microRNA signatures of columnar cell hyperplasia linking Let-7c to precancerous and cancerous breast cancer cell proliferation.

Authors:
Sofie Björner Paul A Fitzpatrick Yaoyong Li Craig Allred Anthony Howell Anita Ringberg Håkan Olsson Crispin J Miller Håkan Axelson Göran Landberg

PLoS One 2014 14;9(8):e105099. Epub 2014 Aug 14.

Center for Molecular Pathology, Skåne University Hospital, Department of Laboratory Medicine Malmö, Lund University, Malmö, Sweden; Breakthrough Breast Cancer Research Unit, Institute of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Paterson Institute for Cancer Research, The Christie National Health Service Foundation Trust, Manchester, United Kingdom; Sahlgrenska Cancer Center, Department of Biomedicine, University of Gothenburg, Gothenburg, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105099PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133372PMC
March 2016

Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.

Authors:
Anna A Marusiak Natalie L Stephenson Hayeon Baik Eleanor W Trotter Yaoyong Li Karen Blyth Susan Mason Phil Chapman Lorena A Puto Jon A Read Claire Brassington Hannah K Pollard Chris Phillips Isabelle Green Ross Overman Matthew Collier Ewelina Testoni Crispin J Miller Tony Hunter Owen J Sansom John Brognard

Cancer Res 2016 Feb 4;76(3):724-35. Epub 2015 Dec 4.

Signalling Networks in Cancer Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-15-0701-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740929PMC
February 2016

GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1.

Authors:
Roshana Thambyrajah Milena Mazan Rahima Patel Victoria Moignard Monika Stefanska Elli Marinopoulou Yaoyong Li Christophe Lancrin Thomas Clapes Tarik Möröy Catherine Robin Crispin Miller Shaun Cowley Berthold Göttgens Valerie Kouskoff Georges Lacaud

Nat Cell Biol 2016 Jan 30;18(1):21-32. Epub 2015 Nov 30.

CRUK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.

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http://dx.doi.org/10.1038/ncb3276DOI Listing
January 2016

Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia.

Authors:
Jizhong Liu Ashish Masurekar Suzanne Johnson Sohini Chakraborty John Griffiths Duncan Smith Seema Alexander Clare Dempsey Catriona Parker Stephanie Harrison Yaoyong Li Crispin Miller Yujun Di Zhumur Ghosh Shekhar Krishnan Vaskar Saha

Oncotarget 2015 Dec;6(40):43048-64

Children's Cancer Group, Institute of Cancer Science, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.18632/oncotarget.5528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767490PMC
December 2015

Evaluation and validation of a robust single cell RNA-amplification protocol through transcriptional profiling of enriched lung cancer initiating cells.

Authors:
Dominic G Rothwell Yaoyong Li Mahmood Ayub Catriona Tate Gillian Newton Yvonne Hey Louise Carter Suzanne Faulkner Massimo Moro Stuart Pepper Crispin Miller Fiona Blackhall Giulia Bertolini Luca Roz Caroline Dive Ged Brady

BMC Genomics 2014 Dec 17;15:1129. Epub 2014 Dec 17.

Nucleic Acid Biomarker Laboratory, Clinical & Experimental Pharmacology, CR-UK Manchester Institute, University of Manchester, Manchester M20 4BX, UK.

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http://dx.doi.org/10.1186/1471-2164-15-1129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320548PMC
December 2014

Investigation of radiosensitivity gene signatures in cancer cell lines.

Authors:
John S Hall Rohan Iype Joana Senra Janet Taylor Lucile Armenoult Kenneth Oguejiofor Yaoyong Li Ian Stratford Peter L Stern Mark J O'Connor Crispin J Miller Catharine M L West

PLoS One 2014 22;9(1):e86329. Epub 2014 Jan 22.

Translational Radiobiology Group, The University of Manchester, Manchester, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086329PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899227PMC
November 2014

Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery.

Authors:
Andrew M Hudson Tim Yates Yaoyong Li Eleanor W Trotter Shameem Fawdar Phil Chapman Paul Lorigan Andrew Biankin Crispin J Miller John Brognard

Cancer Res 2014 Nov 25;74(22):6390-6396. Epub 2014 Sep 25.

Signalling Networks in Cancer Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, M20 4BX, UK.

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http://cancerres.aacrjournals.org/content/74/22/6390.full.pd
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-14-1020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247168PMC
November 2014

JNK suppresses tumor formation via a gene-expression program mediated by ATF2.

Authors:
Malgorzata Gozdecka Stephen Lyons Saki Kondo Janet Taylor Yaoyong Li Jacek Walczynski Gerald Thiel Wolfgang Breitwieser Nic Jones

Cell Rep 2014 Nov 13;9(4):1361-74. Epub 2014 Nov 13.

Department of Cell Regulation, CRUK Manchester Institute, Paterson Building, University of Manchester, Manchester M20 4BX, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.10.043DOI Listing
November 2014

RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence.

Authors:
Michael Lie-A-Ling Elli Marinopoulou Yaoyong Li Rahima Patel Monika Stefanska Constanze Bonifer Crispin Miller Valerie Kouskoff Georges Lacaud

Blood 2014 Sep 31;124(11):e11-20. Epub 2014 Jul 31.

Cancer Research UK Stem Cell Biology Group, and.

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http://dx.doi.org/10.1182/blood-2014-04-572958DOI Listing
September 2014

Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer.

Authors:
Cassandra L Hodgkinson Christopher J Morrow Yaoyong Li Robert L Metcalf Dominic G Rothwell Francesca Trapani Radoslaw Polanski Deborah J Burt Kathryn L Simpson Karen Morris Stuart D Pepper Daisuke Nonaka Alastair Greystoke Paul Kelly Becky Bola Matthew G Krebs Jenny Antonello Mahmood Ayub Suzanne Faulkner Lynsey Priest Louise Carter Catriona Tate Crispin J Miller Fiona Blackhall Ged Brady Caroline Dive

Nat Med 2014 Aug 1;20(8):897-903. Epub 2014 Jun 1.

1] Clinical and Experimental Pharmacology Group, Cancer Research UK Manchester Institute, University of Manchester, Manchester, UK. [2].

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http://dx.doi.org/10.1038/nm.3600DOI Listing
August 2014

A global non-coding RNA system modulates fission yeast protein levels in response to stress.

Authors:
Hui Sun Leong Keren Dawson Chris Wirth Yaoyong Li Yvonne Connolly Duncan L Smith Caroline R M Wilkinson Crispin J Miller

Nat Commun 2014 May 23;5:3947. Epub 2014 May 23.

Applied Computational Biology and Bioinformatics Group, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.

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http://dx.doi.org/10.1038/ncomms4947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050258PMC
May 2014

CXCL12 induces lung cancer cell migration by polarized mtDNA redistribution.

Authors:
Jietao Ma Jiahe Zheng Yaoyong Li Shuling Zhang Dongmei Bai Huawei Zou Chengbo Han

Hum Cell 2014 Jan;27(1):22-8

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http://dx.doi.org/10.1007/s13577-013-0077-4DOI Listing
January 2014

Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer.

Authors:
Shameem Fawdar Eleanor W Trotter Yaoyong Li Natalie L Stephenson Franziska Hanke Anna A Marusiak Zoe C Edwards Sara Ientile Bohdan Waszkowycz Crispin J Miller John Brognard

Proc Natl Acad Sci U S A 2013 Jul 8;110(30):12426-31. Epub 2013 Jul 8.

Signalling Networks in Cancer Group, Cancer Research UK, Paterson Institute for Cancer Research, University of Manchester, Manchester M20 4BX, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1305207110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725071PMC
July 2013

Enhanced detection of ubiquitin isopeptides using reductive methylation.

Authors:
Navin Chicooree Yvonne Connolly Chong-Teik Tan Angeliki Malliri Yaoyong Li Duncan L Smith John R Griffiths

J Am Soc Mass Spectrom 2013 Mar 30;24(3):421-30. Epub 2013 Jan 30.

Paterson Institute for Cancer Research, University of Manchester, Manchester, M20 4BX, UK.

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http://dx.doi.org/10.1007/s13361-012-0538-0DOI Listing
March 2013

Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4--the AdAPT method.

Authors:
Mattias Johansson Angus Roberts Dan Chen Yaoyong Li Manon Delahaye-Sourdeix Niraj Aswani Mark A Greenwood Simone Benhamou Pagona Lagiou Ivana Holcátová Lorenzo Richiardi Kristina Kjaerheim Antonio Agudo Xavier Castellsagué Tatiana V Macfarlane Luigi Barzan Cristina Canova Nalin S Thakker David I Conway Ariana Znaor Claire M Healy Wolfgang Ahrens David Zaridze Neonilia Szeszenia-Dabrowska Jolanta Lissowska Eleonóra Fabiánová Ioan Nicolae Mates Vladimir Bencko Lenka Foretova Vladimir Janout Maria Paula Curado Sergio Koifman Ana Menezes Victor Wünsch-Filho Jose Eluf-Neto Paolo Boffetta Silvia Franceschi Rolando Herrero Leticia Fernandez Garrote Renato Talamini Stefania Boccia Pilar Galan Lars Vatten Peter Thomson Diana Zelenika Mark Lathrop Graham Byrnes Hamish Cunningham Paul Brennan Jon Wakefield James D McKay

PLoS One 2012 25;7(5):e36888. Epub 2012 May 25.

Section of Genetics, International Agency for Research on Cancer (IARC), Lyon, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036888PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360735PMC
December 2012

The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells.

Authors:
William J Harris Xu Huang James T Lynch Gary J Spencer James R Hitchin Yaoyong Li Filippo Ciceri Julian G Blaser Brigit F Greystoke Allan M Jordan Crispin J Miller Donald J Ogilvie Tim C P Somervaille

Cancer Cell 2012 Apr 29;21(4):473-87. Epub 2012 Mar 29.

Cancer Research UK Leukaemia Biology Laboratory, Paterson Institute for Cancer Research, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1016/j.ccr.2012.03.014DOI Listing
April 2012

Programmed fluctuations in sense/antisense transcript ratios drive sexual differentiation in S. pombe.

Authors:
Danny A Bitton Agnes Grallert Paul J Scutt Tim Yates Yaoyong Li James R Bradford Yvonne Hey Stuart D Pepper Iain M Hagan Crispin J Miller

Mol Syst Biol 2011 Dec 20;7:559. Epub 2011 Dec 20.

CRUK Applied Computational Biology and Bioinformatics Group, Cancer Research UK, Paterson Institute for Cancer Research, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1038/msb.2011.90DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738847PMC
December 2011

A comparison of massively parallel nucleotide sequencing with oligonucleotide microarrays for global transcription profiling.

Authors:
James R Bradford Yvonne Hey Tim Yates Yaoyong Li Stuart D Pepper Crispin J Miller

BMC Genomics 2010 May 5;11:282. Epub 2010 May 5.

Applied Computational Biology and Bioinformatics, Cancer Research UK, Paterson Institute for Cancer Research, The University of Manchester, Wilmslow Road, Manchester M20 4BX UK.

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http://dx.doi.org/10.1186/1471-2164-11-282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877694PMC
May 2010