Publications by authors named "Yann Fichou"

61Publications

Mechanisms of Heparin-Induced Tau Aggregation Revealed by a Single Nanopore.

ACS Sens 2020 04 14;5(4):1158-1167. Epub 2020 Apr 14.

Institut Européen des Membranes, UMR5635 UM ENCSM CNRS, Place Eugène Bataillon, 34095 Montpellier Cedex 5, France.

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http://dx.doi.org/10.1021/acssensors.0c00193DOI Listing
April 2020

Electrostatically Driven Complex Coacervation and Amyloid Aggregation of Tau Are Independent Processes with Overlapping Conditions.

ACS Chem Neurosci 2020 02 4;11(4):615-627. Epub 2020 Feb 4.

Department of Chemistry and Biochemistry , University of California , Santa Barbara , California 93106 , United States.

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http://dx.doi.org/10.1021/acschemneuro.9b00627DOI Listing
February 2020

Tau-Cofactor Complexes as Building Blocks of Tau Fibrils.

Front Neurosci 2019 13;13:1339. Epub 2019 Dec 13.

Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA, United States.

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http://dx.doi.org/10.3389/fnins.2019.01339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923735PMC
December 2019

Publisher Correction: Tauopathies: Protein shapes at the core of chronic traumatic encephalopathy.

Nat Struct Mol Biol 2019 Jun;26(6):526

Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, CA, USA.

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http://dx.doi.org/10.1038/s41594-019-0251-9DOI Listing
June 2019

Protein shapes at the core of chronic traumatic encephalopathy.

Nat Struct Mol Biol 2019 05;26(5):336-338

Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, CA, USA.

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http://www.nature.com/articles/s41594-019-0221-2
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http://dx.doi.org/10.1038/s41594-019-0221-2DOI Listing
May 2019

A novel JK null allele in a Brazilian patient with sickle cell disease (SCD).

Transfusion 2019 07 9;59(7):2459-2460. Epub 2019 Apr 9.

UMR1078 - Etablissement Français du Sang, Inserm, Univ Brest, Brest, France.

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http://dx.doi.org/10.1111/trf.15304DOI Listing
July 2019

Functional analysis of novel RHD variants: splicing disruption is likely to be a common mechanism of variant D phenotype.

Transfusion 2019 04 27;59(4):1367-1375. Epub 2019 Feb 27.

UMR1078 "Génétique, Génomique Fonctionnelle et Biotechnologies", INSERM, EFS, Université de Brest, IBSAM, CHU de Brest, Brest, France.

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http://dx.doi.org/10.1111/trf.15210DOI Listing
April 2019

Cofactors are essential constituents of stable and seeding-active tau fibrils.

Proc Natl Acad Sci U S A 2018 12 11;115(52):13234-13239. Epub 2018 Dec 11.

Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106;

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http://dx.doi.org/10.1073/pnas.1810058115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310788PMC
December 2018

Comprehensive phenotypic and molecular investigation of RhD and RhCE variants in Moroccan blood donors.

Blood Transfus 2019 03 24;17(2):151-156. Epub 2018 Oct 24.

Laboratory of Haematology, Cellular and Genetic Engineering, Faculty of Medicine and Pharmacy Casablanca, Hassan II University of Casablanca, Casablanca, Morocco.

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http://www.bloodtransfusion.it/articolosing.aspx?id=000987
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http://dx.doi.org/10.2450/2018.0153-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476734PMC
March 2019

Correction: Heparin-induced tau filaments are structurally heterogeneous and differ from Alzheimer's disease filaments.

Chem Commun (Camb) 2018 08 20;54(62):8653. Epub 2018 Jul 20.

Department of Chemistry, University of California Santa Babara, Santa Barbara, California 93106, USA.

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http://dx.doi.org/10.1039/c8cc90325eDOI Listing
August 2018

RHD-Positive Alleles among D- C/E+ Individuals from India.

Transfus Med Hemother 2018 May 10;45(3):173-177. Epub 2018 Jan 10.

Institut National de la Santé et de la Recherche Médicale (Inserm), UMR1078, Brest, France.

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http://dx.doi.org/10.1159/000479239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006600PMC
May 2018

Heparin-induced tau filaments are structurally heterogeneous and differ from Alzheimer's disease filaments.

Chem Commun (Camb) 2018 05;54(36):4573-4576

Department of chemistry, University of California Santa Babara, Santa Barbara, California 93106, USA.

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http://dx.doi.org/10.1039/c8cc01355aDOI Listing
May 2018

Molecular basis of weak D expression in the Indian population and report of a novel, predominant variant RHD allele.

Transfusion 2018 06 25;58(6):1540-1549. Epub 2018 Feb 25.

National Institute of Immunohaematology (NIIH), Indian Council of Medical Research (ICMR), KEM Hospital Campus, Parel, Mumbai, India.

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http://dx.doi.org/10.1111/trf.14552DOI Listing
June 2018

Spatially Heterogeneous Surface Water Diffusivity around Structured Protein Surfaces at Equilibrium.

J Am Chem Soc 2017 12 27;139(49):17890-17901. Epub 2017 Nov 27.

Department of Chemistry and Biochemistry, University of California, Santa Barbara , Santa Barbara, California 93106, United States.

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http://dx.doi.org/10.1021/jacs.7b08606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021025PMC
December 2017

Conformation-based assay of tau protein aggregation.

Methods Cell Biol 2017 10;141:89-112. Epub 2017 Aug 10.

University of California Santa Barbara, Santa Barbara, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mcb.2017.06.008DOI Listing
June 2018

First report of Rh individuals in the Indian population and characterization of the underlying molecular mechanisms.

Transfusion 2017 08 3;57(8):1944-1948. Epub 2017 May 3.

Institut National de la Santé et de la Recherche Médicale (Inserm), UMR1078, Brest, France.

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http://dx.doi.org/10.1111/trf.14150DOI Listing
August 2017

A ring-shaped conduit connects the mother cell and forespore during sporulation in Bacillus subtilis.

Proc Natl Acad Sci U S A 2016 10 28;113(41):11585-11590. Epub 2016 Sep 28.

Institut de Biologie Structurale (IBS), Université Grenoble Alpes-Commissariat à l'Energie Atomique et aux Energies Alternatives-CNRS, 38044 Grenoble, France;

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http://dx.doi.org/10.1073/pnas.1609604113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068255PMC
October 2016

Identification of novel variant A alleles within the ABO gene.

Transfusion 2016 05 26;56(5):1244-6. Epub 2016 Feb 26.

Etablissement Français du Sang (EFS)-Région Bretagne, Brest.

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http://dx.doi.org/10.1111/trf.13542DOI Listing
May 2016

Insights into RHCE Molecular Analysis in Samples with Partial D Variants: the Experience of Western France.

Transfus Med Hemother 2015 Nov 23;42(6):372-7. Epub 2015 Jul 23.

French Blood Institute (EFS-Bretagne), Brest, France; National Institute of Health and Medical Research (Inserm, UMR1078), Brest, France; Faculty of Medicine and Health Sciences, University of Western Brittany, Brest, France; Molecular Genetics and Histocompatibility Laboratory, Regional University Hospital (CHRU), Morvan Hospital, Brest, France.

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http://dx.doi.org/10.1159/000382086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698597PMC
November 2015

Molecular Dynamics Simulations of a Powder Model of the Intrinsically Disordered Protein Tau.

J Phys Chem B 2015 Oct 18;119(39):12580-9. Epub 2015 Sep 18.

Department of Chemistry, University of California , Irvine, California 92697-2025, United States.

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http://dx.doi.org/10.1021/acs.jpcb.5b05849DOI Listing
October 2015

Molecular RHD-RHCE Analysis by Multiplex PCR of Short Fluorescent Fragments.

Methods Mol Biol 2015 ;1310:97-104

Etablissement Français du Sang (EFS) - Bretagne, 46 rue Félix Le Dantec, 29218, Brest, France,

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http://dx.doi.org/10.1007/978-1-4939-2690-9_8DOI Listing
February 2016

Hydration water mobility is enhanced around tau amyloid fibers.

Proc Natl Acad Sci U S A 2015 May 27;112(20):6365-70. Epub 2015 Apr 27.

Université Grenoble Alpes, CNRS, and Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Institut de Biologie Structurale, 38044 Grenoble, France;

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http://dx.doi.org/10.1073/pnas.1422824112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443308PMC
May 2015

Extensive functional analyses of RHD splice site variants: Insights into the potential role of splicing in the physiology of Rh.

Transfusion 2015 Jun 21;55(6 Pt 2):1432-43. Epub 2015 Mar 21.

Institut National de la Santé et de la Recherche Médicale (Inserm), UMR1078.

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http://dx.doi.org/10.1111/trf.13083DOI Listing
June 2015

Next-generation sequencing is a credible strategy for blood group genotyping.

Br J Haematol 2014 Nov 19;167(4):554-62. Epub 2014 Aug 19.

Institut National de la Santé et de la Recherche Médicale (INSERM), U1078, Brest, France; Etablissement Français du Sang (EFS) - Bretagne, Brest, France.

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http://dx.doi.org/10.1111/bjh.13084DOI Listing
November 2014

Distribution of Rhesus blood group antigens and weak D alleles in the population of Albania.

Blood Transfus 2014 Oct 12;12(4):565-9. Epub 2014 Jun 12.

French Blood Institute (EFS-Bretagne), Brest, France National Institute of Health and Medical Research (Inserm U1078), Brest, France.

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http://dx.doi.org/10.2450/2014.0240-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212038PMC
October 2014

A missense mutation in the alpha-actinin 1 gene (ACTN1) is the cause of autosomal dominant macrothrombocytopenia in a large French family.

PLoS One 2013 17;8(9):e74728. Epub 2013 Sep 17.

Institut National de la Santé et de la Recherche Médicale (INSERM), U1078, Brest, France ; Faculté de Médecine et des Sciences de la Santé, Université de Bretagne Occidentale (UBO), Brest, France ; Laboratoire de Génétique Moléculaire et d'Histocompatibilité, Centre Hospitalier Universitaire (CHU) Brest, Hôpital Morvan, Brest, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074728PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775762PMC
June 2014

A convenient qualitative and quantitative method to investigate RHD-RHCE hybrid genes.

Transfusion 2013 Nov 3;53(11 Suppl 2):2974-82. Epub 2013 Apr 3.

Etablissement Français du Sang (EFS)-Bretagne, Brest, France; Institut National de la Santé et de la Recherche Médicale (INSERM), U1078, Brest, France; Faculté de Médecine et des Sciences de la Santé, Université de Bretagne Occidentale, Brest, France; Laboratoire de Génétique Moléculaire et d'Histocompatibilité, Centre Hospitalier Régional Universitaire (CHRU), Hôpital Morvan, Brest, France.

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http://doi.wiley.com/10.1111/trf.12179
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http://dx.doi.org/10.1111/trf.12179DOI Listing
November 2013

Weak D caused by a founder deletion in the RHD gene.

Transfusion 2012 Nov 15;52(11):2348-55. Epub 2012 Mar 15.

Etablissement Français du Sang (EFS)-Bretagne, France.

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http://dx.doi.org/10.1111/j.1537-2995.2012.03606.xDOI Listing
November 2012

A FOXG1 mutation in a boy with congenital variant of Rett syndrome.

Neurogenetics 2011 Feb 24;12(1):1-8. Epub 2010 Aug 24.

Institut Cochin, Inserm U1016, UMR8104, Université Paris Descartes, 24 rue du Faubourg St Jacques, 75014, Paris, France.

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http://dx.doi.org/10.1007/s10048-010-0255-4DOI Listing
February 2011

Somatic mosaicism for a CDKL5 mutation as an epileptic encephalopathy in males.

Am J Med Genet A 2010 Aug;152A(8):2110-1

Laboratoire de Biochimie et Biologie Moléculaire, AP-HP, Hôpital Cochin, Paris, France.

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http://dx.doi.org/10.1002/ajmg.a.33037DOI Listing
August 2010

Epileptic encephalopathy in a girl with an interstitial deletion of Xp22 comprising promoter and exon 1 of the CDKL5 gene.

Am J Med Genet B Neuropsychiatr Genet 2010 Jan;153B(1):202-7

Service de Neurologie Pédiatrique, Département de Pédiatrie, Hôpital Necker Enfants Malades, AP-HP, Paris, France.

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http://dx.doi.org/10.1002/ajmg.b.30974DOI Listing
January 2010

The first missense mutation causing Rett syndrome specifically affecting the MeCP2_e1 isoform.

Neurogenetics 2009 Apr 26;10(2):127-33. Epub 2008 Nov 26.

Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France.

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http://dx.doi.org/10.1007/s10048-008-0161-1DOI Listing
April 2009

Annexin V is directly involved in cystic fibrosis transmembrane conductance regulator's chloride channel function.

Biochim Biophys Acta 2007 Oct 11;1772(10):1121-33. Epub 2007 Aug 11.

INSERM, Unité 613, 46 rue Félix le Dantec, BP62025, 29220 Brest, France.

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http://dx.doi.org/10.1016/j.bbadis.2007.06.006DOI Listing
October 2007

Estimating the age of CFTR mutations predominantly found in Brittany (Western France).

J Cyst Fibros 2008 Mar 6;7(2):168-73. Epub 2007 Sep 6.

Inserm, U613, Génétique Moléculaire et Génétique Epidémiologique, Etablissement Français du Sang, 46 rue Félix Le Dantec, BP62025, F-29220, Brest, France.

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http://dx.doi.org/10.1016/j.jcf.2007.07.009DOI Listing
March 2008

The potential of oligonucleotides for therapeutic applications.

Trends Biotechnol 2006 Dec 12;24(12):563-70. Epub 2006 Oct 12.

Inserm U613, Université de Bretagne Occidentale, 46 rue Félix Le Dantec, 29275 Brest Cedex, France.

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http://dx.doi.org/10.1016/j.tibtech.2006.10.003DOI Listing
December 2006

Interaction of dystrophin rod domain with membrane phospholipids. Evidence of a close proximity between tryptophan residues and lipids.

J Biol Chem 2003 Feb 11;278(8):5993-6001. Epub 2002 Dec 11.

Laboratoire de Résonance Magnétique Nucléaire en Biologie et Médecine, Unité Propre de Recherche de l'Enseignement Supérieur EA 2230, Faculté de Médecine, CS 34317, Rennes 35043 cedex, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M207321200
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http://dx.doi.org/10.1074/jbc.M207321200DOI Listing
February 2003