Publications by authors named "Yann Abraham"

10 Publications

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Deep immune profiling of patients treated with lenalidomide and dexamethasone with or without daratumumab.

Authors:
Tineke Casneuf Homer C Adams Niels W C J van de Donk Yann Abraham Jaime Bald Greet Vanhoof Koen Van der Borght Tina Smets Brad Foulk Karl C Nielsen Joshua Rusbuldt Amy Axel Andrew Lysaght Hugo Ceulemans Frederik Stevenaert Saad Z Usmani Torben Plesner Herve Avet-Loiseau Inger Nijhof Tuna Mutis Jordan M Schecter Christopher Chiu Nizar J Bahlis

Leukemia 2021 02 26;35(2):573-584. Epub 2020 May 26.

Arnie Charbonneau Cancer Research Institute, University of Calgary, Calgary, AB, Canada.

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February 2021

High-Parameter Mass Cytometry Evaluation of Relapsed/Refractory Multiple Myeloma Patients Treated with Daratumumab Demonstrates Immune Modulation as a Novel Mechanism of Action.

Authors:
Homer C Adams Frederik Stevenaert Jakub Krejcik Koen Van der Borght Tina Smets Jaime Bald Yann Abraham Hugo Ceulemans Christopher Chiu Greet Vanhoof Saad Z Usmani Torben Plesner Sagar Lonial Inger Nijhof Henk M Lokhorst Tuna Mutis Niels W C J van de Donk Amy Kate Sasser Tineke Casneuf

Cytometry A 2019 03 11;95(3):279-289. Epub 2018 Dec 11.

Janssen Research & Development, Beerse, Belgium.

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March 2019

Exploring Glucocorticoid Receptor Agonists Mechanism of Action Through Mass Cytometry and Radial Visualizations.

Authors:
Yann Abraham Bertran Gerrits Marie-Gabrielle Ludwig Michael Rebhan Caroline Gubser Keller

Cytometry B Clin Cytom 2017 01;92(1):42-56

Developmental and Molecular Pathway, Computational Biology, Novartis Institute for Biomedical Research, Novartis Campus, CH-4056 Basel, Switzerland.

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January 2017

Jenkins-CI, an Open-Source Continuous Integration System, as a Scientific Data and Image-Processing Platform.

Authors:
Ioannis K Moutsatsos Imtiaz Hossain Claudia Agarinis Fred Harbinski Yann Abraham Luc Dobler Xian Zhang Christopher J Wilson Jeremy L Jenkins Nicholas Holway John Tallarico Christian N Parker

SLAS Discov 2017 03 13;22(3):238-249. Epub 2016 Dec 13.

3 Developmental and Molecular Pathways, NIBR, Postfach, Basel, Switzerland.

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March 2017

YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.

Authors:
Patricia Marti Claudia Stein Tanja Blumer Yann Abraham Michael T Dill Monika Pikiolek Vanessa Orsini Giorgia Jurisic Philippe Megel Zuzanna Makowska Claudia Agarinis Luigi Tornillo Tewis Bouwmeester Heinz Ruffner Andreas Bauer Christian N Parker Tobias Schmelzle Luigi M Terracciano Markus H Heim Jan S Tchorz

Hepatology 2015 Nov 25;62(5):1497-510. Epub 2015 Aug 25.

Novartis Institutes for Biomedical Research, Developmental and Molecular Pathways, Novartis Pharma AG, Basel, Switzerland.

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November 2015

Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways.

Authors:
Delphine Rispal Sandra Eltschinger Michael Stahl Stefania Vaga Bernd Bodenmiller Yann Abraham Ireos Filipuzzi N Rao Movva Ruedi Aebersold Stephen B Helliwell Robbie Loewith

J Biol Chem 2015 Jun 16;290(24):14963-78. Epub 2015 Apr 16.

From the Department of Molecular Biology and Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, 1211 Geneva, the National Centre for Competence in Research Chemical Biology, 1211 Geneva, Switzerland

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June 2015

Multiparametric Analysis of Screening Data: Growing Beyond the Single Dimension to Infinity and Beyond.

Authors:
Yann Abraham Xian Zhang Christian N Parker

J Biomol Screen 2014 Jun 5;19(5):628-39. Epub 2014 Mar 5.

Novartis Institute for Biomedical Research, Basel, Switzerland.

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June 2014

High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions.

Authors:
Dominic Hoepfner Stephen B Helliwell Heather Sadlish Sven Schuierer Ireos Filipuzzi Sophie Brachat Bhupinder Bhullar Uwe Plikat Yann Abraham Marc Altorfer Thomas Aust Lukas Baeriswyl Raffaele Cerino Lena Chang David Estoppey Juerg Eichenberger Mathias Frederiksen Nicole Hartmann Annika Hohendahl Britta Knapp Philipp Krastel Nicolas Melin Florian Nigsch Edward J Oakeley Virginie Petitjean Frank Petersen Ralph Riedl Esther K Schmitt Frank Staedtler Christian Studer John A Tallarico Stefan Wetzel Mark C Fishman Jeffrey A Porter N Rao Movva

Microbiol Res 2014 Feb-Mar;169(2-3):107-20. Epub 2013 Dec 1.

Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland.

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September 2014

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.

Authors:
Marcus Bantscheff Carsten Hopf Mikhail M Savitski Antje Dittmann Paola Grandi Anne-Marie Michon Judith Schlegl Yann Abraham Isabelle Becher Giovanna Bergamini Markus Boesche Manja Delling Birgit Dümpelfeld Dirk Eberhard Carola Huthmacher Toby Mathieson Daniel Poeckel Valérie Reader Katja Strunk Gavain Sweetman Ulrich Kruse Gitte Neubauer Nigel G Ramsden Gerard Drewes

Nat Biotechnol 2011 Mar 23;29(3):255-65. Epub 2011 Jan 23.

Cellzome AG, Heidelberg, Germany.

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March 2011

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors.

Authors:
Marcus Bantscheff Dirk Eberhard Yann Abraham Sonja Bastuck Markus Boesche Scott Hobson Toby Mathieson Jessica Perrin Manfred Raida Christina Rau Valérie Reader Gavain Sweetman Andreas Bauer Tewis Bouwmeester Carsten Hopf Ulrich Kruse Gitte Neubauer Nigel Ramsden Jens Rick Bernhard Kuster Gerard Drewes

Nat Biotechnol 2007 Sep 26;25(9):1035-44. Epub 2007 Aug 26.

Cellzome AG, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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September 2007