Yanmin Zhang

Yanmin Zhang

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Igfbp3 in grass carp (Ctenopharyngodon idellus): Molecular identification and mRNA expression under glucose, insulin and glucagon.

Comp Biochem Physiol B Biochem Mol Biol 2020 Apr 19;242:110394. Epub 2019 Dec 19.

College of Fisheries, Henan Normal University, Xinxiang 453007, People's Republic of China; College of Fisheries, Engineering Technology Research Center of Henan Province for Aquatic Animal Cultivation, Henan Normal University, Xinxiang 453007, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.cbpb.2019.110394DOI Listing
April 2020

Evodiamine suppresses Notch3 signaling in lung tumorigenesis via direct binding to γ-secretases.

Phytomedicine 2020 Mar 31;68:153176. Epub 2020 Jan 31.

Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2020.153176DOI Listing
March 2020

Integrative strategy to determine residual proteins in cefaclor produced by immobilized penicillin G acylase.

J Pharm Biomed Anal 2020 Mar 4;185:113229. Epub 2020 Mar 4.

Department of Antibiotics, National Institutes for Food and Drug Control, Beijing 102629, China. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2020.113229DOI Listing
March 2020

Shh Overexpression Is Correlated with GRP78 and AR Expression in Primary Prostate Cancer: Clinicopathological Features and Outcomes in a Chinese Cohort.

Cancer Manag Res 2020 3;12:1569-1578. Epub 2020 Mar 3.

Department of Pathology, Jining First People's Hospital, Jining Medical University, Jining 272000, People's Republic of China.

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http://dx.doi.org/10.2147/CMAR.S231218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060775PMC
March 2020

Homoharringtonine suppresses LoVo cell growth by inhibiting EphB4 and the PI3K/AKT and MAPK/EKR1/2 signaling pathways.

Food Chem Toxicol 2020 Feb 11;136:110960. Epub 2019 Nov 11.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, No. 76, Yanta Weststreet, #54, Xi'an, Shaanxi Province, 710061, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2019.110960DOI Listing
February 2020

Sanguinarine disrupts the colocalization and interaction of HIF-1α with tyrosine and serine phosphorylated-STAT3 in breast cancer.

J Cell Mol Med 2020 Feb 17. Epub 2020 Feb 17.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, P.R. China.

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http://dx.doi.org/10.1111/jcmm.15056DOI Listing
February 2020

Molecular cloning of SLC35D3 and analysis of its role during porcine intramuscular preadipocyte differentiation.

BMC Genet 2020 02 22;21(1):20. Epub 2020 Feb 22.

Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Technology, Shandong Agricultural University, 61 Daizong Street, Tai'an, 271018, People's Republic of China.

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http://dx.doi.org/10.1186/s12863-020-0822-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036214PMC
February 2020

HIF-1α/Actl6a/H3K9ac axis is critical for pluripotency and lineage differentiation of human induced pluripotent stem cells.

FASEB J 2020 Feb 28. Epub 2020 Feb 28.

Central Laboratory, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen, China.

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http://dx.doi.org/10.1096/fj.201902829RRDOI Listing
February 2020

[New early gastric cancer marker PRDX4 promote the tumorigenesis and progression of gastric cancer via eliminating ROS].

Sheng Wu Gong Cheng Xue Bao 2020 Feb;36(2):320-331

Institute of Biochemistry and Molecular Biology, Lanzhou University, Lanzhou 730000, Gansu, China.

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http://dx.doi.org/10.13345/j.cjb.190202DOI Listing
February 2020

TPD7 inhibits the growth of cutaneous T cell lymphoma H9 cell through regulating IL-2R signalling pathway.

J Cell Mol Med 2020 Jan 19;24(1):984-995. Epub 2019 Nov 19.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.

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http://dx.doi.org/10.1111/jcmm.14810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933353PMC
January 2020

In Silico Design and Analysis of a Kinase-Focused Combinatorial Library Considering Diversity and Quality.

J Chem Inf Model 2020 Jan 10;60(1):92-107. Epub 2020 Jan 10.

Laboratory of Molecular Design and Drug Discovery, School of Science , China Pharmaceutical University , 639 Longmian Avenue , Nanjing 211198 , China.

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http://dx.doi.org/10.1021/acs.jcim.9b00841DOI Listing
January 2020

Electrodeposited poly(3,4-ethylenedioxythiophene) doped with graphene oxide for the simultaneous voltammetric determination of ascorbic acid, dopamine and uric acid.

Mikrochim Acta 2020 01 4;187(1):94. Epub 2020 Jan 4.

School of Pharmacy, Xi'an Jiaotong University, Xi'an, 710061, China.

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http://dx.doi.org/10.1007/s00604-019-4083-4DOI Listing
January 2020

Discovery of novel coumarin derivatives as potent and orally bioavailable BRD4 inhibitors based on scaffold hopping.

J Enzyme Inhib Med Chem 2019 Dec;34(1):808-817

a Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province , Institute of Materia Medica, Zhejiang Academy of Medical Sciences , Hangzhou , PR China.

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https://www.tandfonline.com/doi/full/10.1080/14756366.2019.1
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http://dx.doi.org/10.1080/14756366.2019.1587417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427567PMC
December 2019

Investigation of Crystal Structures in Structure-Based Virtual Screening for Protein Kinase Inhibitors.

J Chem Inf Model 2019 Dec 15;59(12):5244-5262. Epub 2019 Nov 15.

Laboratory of Molecular Design and Drug Discovery, School of Science , China Pharmaceutical University , 639 Longmian Avenue , Nanjing 211198 , China.

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http://dx.doi.org/10.1021/acs.jcim.9b00684DOI Listing
December 2019

Generation of induced pluripotent stem cells (iPSCs) from an infant with Pompe disease carrying with compound mutations of R608X and E888X in GAA gene.

Stem Cell Res 2019 12 25;41:101621. Epub 2019 Oct 25.

Xi'an Medicine University, Xi'an 710021, China.

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http://dx.doi.org/10.1016/j.scr.2019.101621DOI Listing
December 2019

Direct electrochemistry of glucose oxidase based on one step electrodeposition of reduced graphene oxide incorporating polymerized l-lysine and its application in glucose sensing.

Mater Sci Eng C Mater Biol Appl 2019 Nov 14;104:109880. Epub 2019 Jun 14.

School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China. Electronic address:

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http://dx.doi.org/10.1016/j.msec.2019.109880DOI Listing
November 2019

Investigation of Machine Intelligence in Compound Cell Activity Classification.

Mol Pharm 2019 11 21;16(11):4472-4484. Epub 2019 Oct 21.

Laboratory of Molecular Design and Drug Discovery, School of Science , China Pharmaceutical University , 639 Longmian Avenue , Nanjing 211198 , China.

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http://dx.doi.org/10.1021/acs.molpharmaceut.9b00558DOI Listing
November 2019

Regulation of C-reactive protein conformation in inflammation.

Inflamm Res 2019 Oct 16;68(10):815-823. Epub 2019 Jul 16.

Children's Research Institute, Xi'an Key Laboratory of Children's Health and Diseases, Affiliated Children Hospital, Xi'an Jiaotong University, 69# Xijuyuan Lane, Lianhu District, Xi'an, 710003, Shaanxi, China.

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http://dx.doi.org/10.1007/s00011-019-01269-1DOI Listing
October 2019

HMQ‑T‑F2 suppresses migration of the human cervical cancer HeLa cells by reversing EMT via the PI3K/Akt signaling pathway.

Oncol Rep 2019 Oct 23;42(4):1451-1458. Epub 2019 Jul 23.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.

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http://dx.doi.org/10.3892/or.2019.7245DOI Listing
October 2019

Discovery of potent apoptosis signal-regulating kinase 1 inhibitors via integrated computational strategy and biological evaluation.

J Biomol Struct Dyn 2019 Oct 23:1-12. Epub 2019 Oct 23.

School of Science, China Pharmaceutical University , Nanjing , Jiangsu , China.

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http://dx.doi.org/10.1080/07391102.2019.1680439DOI Listing
October 2019

Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways.

Acta Pharm 2019 Sep;69(3):423-431

School of Pharmacy, Xi'an Jiaotong University, 710061 Xi'an, ShaanxiChina.

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http://dx.doi.org/10.2478/acph-2019-0021DOI Listing
September 2019

Prediction of hERG K+ channel blockage using deep neural networks.

Chem Biol Drug Des 2019 Sep 6;94(5):1973-1985. Epub 2019 Sep 6.

Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, Nanjing, China.

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http://dx.doi.org/10.1111/cbdd.13600DOI Listing
September 2019

In Silico Prediction of Human Intravenous Pharmacokinetic Parameters with Improved Accuracy.

J Chem Inf Model 2019 Sep 26;59(9):3968-3980. Epub 2019 Aug 26.

School of Science , China Pharmaceutical University , 639 Longmian Avenue , Nanjing , Jiangsu 211198 , China.

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http://dx.doi.org/10.1021/acs.jcim.9b00300DOI Listing
September 2019

Detailed insight into the formation of protein corona: Conformational change, stability and aggregation.

Int J Biol Macromol 2019 Aug 4;135:1114-1122. Epub 2019 Jun 4.

Key Laboratory of Green Chemical Media and Reactions, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ijbiomac.2019.06.014DOI Listing
August 2019

A redox sensitivity-based method to quantify both pentameric and monomeric C-reactive protein in a single assay.

J Immunol Methods 2019 Jul 26;470:40-45. Epub 2019 Apr 26.

Children's Research Institute, Xi'an Key Laboratory of Children's Health and Diseases, Affiliated Children Hospital, Xi'an Jiaotong University, Xi'an 710043, Shaanxi, China. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2019.04.009DOI Listing
July 2019

Protein-ligand interaction-guided discovery of novel VEGFR-2 inhibitors.

J Biomol Struct Dyn 2019 Jul 2:1-16. Epub 2019 Jul 2.

a Laboratory of Molecular Design and Drug Discovery, School of Science , China Pharmaceutical University , Nanjing , China.

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http://dx.doi.org/10.1080/07391102.2019.1635915DOI Listing
July 2019

Targeting receptor tyrosine kinase EphB4 in cancer therapy.

Semin Cancer Biol 2019 06 6;56:37-46. Epub 2017 Oct 6.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, No. 76, Yanta West Street, #54, Xi'an, Shaanxi Province 710061, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2017.10.002DOI Listing
June 2019

Combination of SB431542, CHIR99021 and PD0325901 has a synergic effect on abrogating valproic acid‑induced epithelial‑mesenchymal transition and stemness in HeLa, 5637 and SCC‑15 cells.

Oncol Rep 2019 Jun 1;41(6):3545-3554. Epub 2019 Apr 1.

Ultrasound Department, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China.

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http://dx.doi.org/10.3892/or.2019.7088DOI Listing
June 2019

Ultrasound and Redox-Triggered Morphology Transitions of Supramolecular Self-assemblies with pH Responsiveness for Triple-Controlled Release.

Langmuir 2019 Jun 7;35(24):8045-8051. Epub 2019 Jun 7.

MOE Key Laboratory of Material Physics and Chemistry under Extraordinary Conditions, Shanxi Key Laboratory of Macromolecular Science and Technology, School of Science , Northwestern Polytechnical University , Xi'an 710072 , P. R. China.

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http://pubs.acs.org/doi/10.1021/acs.langmuir.9b01153
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http://dx.doi.org/10.1021/acs.langmuir.9b01153DOI Listing
June 2019

A combined drug discovery strategy based on machine learning and molecular docking.

Chem Biol Drug Des 2019 05 7;93(5):685-699. Epub 2019 Mar 7.

Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, Nanjing, China.

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http://dx.doi.org/10.1111/cbdd.13494DOI Listing
May 2019

pH-sensitive doxorubicin-loaded polymeric nanocomplex based on β-cyclodextrin for liver cancer-targeted therapy.

Int J Nanomedicine 2019 21;14:1997-2010. Epub 2019 Mar 21.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China,

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http://dx.doi.org/10.2147/IJN.S193170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433111PMC
May 2019

Dynamic Transcriptome Analysis Reveals Potential Long Non-coding RNAs Governing Postnatal Pineal Development in Pig.

Front Genet 2019 3;10:409. Epub 2019 May 3.

Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Sciences and Engineering, Foshan University, Foshan, China.

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http://dx.doi.org/10.3389/fgene.2019.00409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510172PMC
May 2019

Synergistic effect of berberine and HMQ1611 impairs cell proliferation and migration by regulating Wnt signaling pathway in hepatocellular carcinoma.

Phytother Res 2019 Mar 18;33(3):745-755. Epub 2018 Dec 18.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.

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http://dx.doi.org/10.1002/ptr.6267DOI Listing
March 2019

Effects of melatonin on the synthesis of estradiol and gene expression in pig granulosa cells.

J Pineal Res 2019 Mar 31;66(2):e12546. Epub 2019 Jan 31.

The State Key Laboratory for Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.

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http://dx.doi.org/10.1111/jpi.12546DOI Listing
March 2019

Discovery of potent Pan-Raf inhibitors with increased solubility to overcome drug resistance.

Eur J Med Chem 2019 Feb 16;163:243-255. Epub 2018 Nov 16.

School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, Jiangsu, 211198, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234183099
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http://dx.doi.org/10.1016/j.ejmech.2018.11.033DOI Listing
February 2019

Ephrin type-B receptor 4 affinity chromatography: An effective and rapid method studying the active compounds targeting Ephrin type-B receptor 4.

J Chromatogr A 2019 Feb 4;1586:82-90. Epub 2018 Dec 4.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2018.12.005DOI Listing
February 2019

NRDR inhibits estradiol synthesis and is associated with changes in reproductive traits in pigs.

Mol Reprod Dev 2019 01 23;86(1):63-74. Epub 2018 Nov 23.

The State Key Laboratory for Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.

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http://doi.wiley.com/10.1002/mrd.23080
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http://dx.doi.org/10.1002/mrd.23080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587779PMC
January 2019

HMQ-T-F5 (1-(4-(2-aminoquinazolin-7-yl)phenyl)-3-(2‑bromo‑5- (trifluoromethoxy)phenyl) thiourea) suppress proliferation and migration of human cervical HeLa cells via inhibiting Wnt/β-catenin signaling pathway.

Phytomedicine 2018 Dec 27;51:48-57. Epub 2018 Jun 27.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, No. 76, Yanta West Street, #54, Xi'an 710061, Shaanxi Province, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2018.06.028DOI Listing
December 2018

ADME properties evaluation in drug discovery: in silico prediction of blood-brain partitioning.

Mol Divers 2018 Nov 6;22(4):979-990. Epub 2018 Aug 6.

Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, Jiangsu, People's Republic of China.

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http://link.springer.com/10.1007/s11030-018-9866-8
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http://dx.doi.org/10.1007/s11030-018-9866-8DOI Listing
November 2018

HMQ-T-B10 induces human liver cell apoptosis by competitively targeting EphrinB2 and regulating its pathway.

J Cell Mol Med 2018 11 14;22(11):5231-5243. Epub 2018 Sep 14.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.

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http://dx.doi.org/10.1111/jcmm.13729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201340PMC
November 2018

[Analysis of genotype-phenotype correlation for a novel MYH7-D554Y mutation identified in an ethnic Han Chinese pedigree affected with hypertrophic cardiomyopathy].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2018 Oct;35(5):667-671

Department of Ultrasound, the First Affiliated Hospital of the Air Force Medical University, Xi'an, Shaanxi 710032, China.

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http://dx.doi.org/10.3760/cma.j.issn.1003-9406.2018.05.010DOI Listing
October 2018

Abundant and Rare Microbial Biospheres Respond Differently to Environmental and Spatial Factors in Tibetan Hot Springs.

Front Microbiol 2018 19;9:2096. Epub 2018 Sep 19.

State Key Laboratory of Biocontrol and Guangdong Provincial Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.

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https://www.frontiersin.org/article/10.3389/fmicb.2018.02096
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http://dx.doi.org/10.3389/fmicb.2018.02096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156277PMC
September 2018

Salvianolic acid A ameliorates renal ischemia/reperfusion injury by activating Akt/mTOR/4EBP1 signaling pathway.

Am J Physiol Renal Physiol 2018 08 31;315(2):F254-F262. Epub 2018 Jan 31.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.

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http://dx.doi.org/10.1152/ajprenal.00508.2017DOI Listing
August 2018

A novel biphenyl urea compound, TPD7, stimulates apoptosis through modulating Fas signaling and Bcl-2 family proteins in cervical cancer.

Oncol Rep 2018 Aug 4;40(2):1064-1072. Epub 2018 Jun 4.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.

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http://dx.doi.org/10.3892/or.2018.6472DOI Listing
August 2018

Novel compounds TAD-1822-7-F2 and F5 inhibited HeLa cells growth through the JAK/Stat signaling pathway.

Biomed Pharmacother 2018 Jul 24;103:118-126. Epub 2018 Apr 24.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, No. 76, Yanta Weststreet, #54, Xi'an, Shaanxi Province 710061, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2018.03.174DOI Listing
July 2018

LIN28A inhibits lysosome‑associated membrane glycoprotein 1 protein expression in embryonic stem and bladder cancer cells.

Mol Med Rep 2018 Jul 3;18(1):399-406. Epub 2018 May 3.

Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Shenzhen, Guangdong 518036, P.R. China.

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http://dx.doi.org/10.3892/mmr.2018.8965DOI Listing
July 2018

Wnt/β-catenin signaling pathway is involved in regulating the migration by an effective natural compound brucine in LoVo cells.

Phytomedicine 2018 Jul 10;46:85-92. Epub 2018 Apr 10.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, No. 76, Yanta Weststreet, #54, Xi'an, Shaanxi 710061, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2018.04.019DOI Listing
July 2018

Insight into the key features for ligand binding in Y1230 mutated c-Met kinase domain by molecular dynamics simulations.

J Biomol Struct Dyn 2018 Jun 20;36(8):2015-2031. Epub 2017 Jun 20.

a State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease and Laboratory of Molecular Design and Drug Discovery , China Pharmaceutical University , 24 Tongjiaxiang, Nanjing 210009 , P.R. China.

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https://www.tandfonline.com/doi/full/10.1080/07391102.2017.1
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http://dx.doi.org/10.1080/07391102.2017.1340852DOI Listing
June 2018

Thermostability Improvement of the d-Allulose 3-Epimerase from Dorea sp. CAG317 by Site-Directed Mutagenesis at the Interface Regions.

J Agric Food Chem 2018 Jun 29;66(22):5593-5601. Epub 2018 May 29.

State Key Laboratory of Food Science and Technology , Jiangnan University , Wuxi , Jiangsu 214122 , China.

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http://dx.doi.org/10.1021/acs.jafc.8b01200DOI Listing
June 2018

Application of the CRISPR/Cas9 System to Drug Resistance in Breast Cancer.

Adv Sci (Weinh) 2018 Jun 15;5(6):1700964. Epub 2018 Apr 15.

School of Pharmacy Health Science Center Xi'an Jiaotong University Xi'an Shaanxi Province 710061 P. R. China.

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http://dx.doi.org/10.1002/advs.201700964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010891PMC
June 2018

Endometrioid Endometrial Carcinoma With Spindle Cells-Aberrant p16 and p53 Expression.

Int J Surg Pathol 2018 Jun 1:1066896918781730. Epub 2018 Jun 1.

2 John H. Stroger, Jr. Hospital, Chicago, IL, USA.

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http://dx.doi.org/10.1177/1066896918781730DOI Listing
June 2018

HMQ-T-F2 exert antitumour effects by upregulation of Axin in human cervical HeLa cells.

J Cell Mol Med 2018 05 7;22(5):2955-2959. Epub 2018 Mar 7.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.

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http://dx.doi.org/10.1111/jcmm.13577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908098PMC
May 2018

Percutaneous intramyocardial septal radiofrequency ablation of hypertrophic obstructive cardiomyopathy: a novel minimally invasive treatment for reduction of outflow tract obstruction.

EuroIntervention 2018 04 6;13(18):e2112-e2113. Epub 2018 Apr 6.

Department of Ultrasound, Xijing Hypertrophic Cardiomyopathy Center, Xijing Hospital, Fourth Military Medical University, Xi'an, Shannxi, China.

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http://dx.doi.org/10.4244/EIJ-D-17-00657DOI Listing
April 2018

Arctigenin exerts protective effects against myocardial infarction via regulation of iNOS, COX‑2, ERK1/2 and HO‑1 in rats.

Mol Med Rep 2018 Mar 10;17(3):4839-4845. Epub 2018 Jan 10.

Department of Cardiology, Liaocheng People's Hospital of Shandong, Liaocheng, Shandong 252000, P.R. China.

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http://dx.doi.org/10.3892/mmr.2018.8420DOI Listing
March 2018

Corticotropin-Releasing Hormone Suppresses Synapse Formation in the Hippocampus of Male Rats via Inhibition of CXCL5 Secretion by Glia.

Endocrinology 2018 02;159(2):622-638

Department of Physiology, Second Military Medical University, Shanghai, China.

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http://dx.doi.org/10.1210/en.2017-00336DOI Listing
February 2018

Discovery of Novel Potent VEGFR-2 Inhibitors Exerting Significant Antiproliferative Activity against Cancer Cell Lines.

J Med Chem 2018 01 19;61(1):140-157. Epub 2017 Dec 19.

School of Science, China Pharmaceutical University , 639 Longmian Avenue, Nanjing 211198, China.

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http://dx.doi.org/10.1021/acs.jmedchem.7b01091DOI Listing
January 2018

Inhibition of Human Cancer Cell Growth by Analogues of Antimycin A.

Planta Med 2017 Dec 8;83(18):1377-1383. Epub 2017 Jun 8.

Biodesign Center for BioEnergetics and School of Molecular Sciences, Arizona State University, Tempe, AZ, USA.

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http://dx.doi.org/10.1055/s-0043-112343DOI Listing
December 2017

On-Surface Synthesis of Adenine Oligomers via Ullmann Reaction.

Chemphyschem 2017 Dec 15;18(24):3544-3547. Epub 2017 Nov 15.

Interdisciplinary Materials Research Center, Tongji-Aarhus Joint Research Center for Nanostructures and Functional Nanomaterials, College of Materials Science and Engineering, Tongji University, Caoan Road 4800, Shanghai, 201804, P. R. China.

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http://dx.doi.org/10.1002/cphc.201701009DOI Listing
December 2017

NS1643 enhances ionic currents in a G604S-WT hERG co-expression system associated with long QT syndrome 2.

Clin Exp Pharmacol Physiol 2017 Nov 5;44(11):1125-1133. Epub 2017 Sep 5.

Department of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University, Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University), Ministry of Education, Xi'an, Shaanxi, China.

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http://dx.doi.org/10.1111/1440-1681.12820DOI Listing
November 2017

Novel CD123-aptamer-originated targeted drug trains for selectively delivering cytotoxic agent to tumor cells in acute myeloid leukemia theranostics.

Drug Deliv 2017 Nov;24(1):1216-1229

a Shaanxi Institute of Pediatric Diseases , Xi'an Children's Hospital , Xi'an , Shaanxi , People's Republic of China.

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http://dx.doi.org/10.1080/10717544.2017.1367976DOI Listing
November 2017

Dihydroberberine exhibits synergistic effects with sunitinib on NSCLC NCI-H460 cells by repressing MAP kinase pathways and inflammatory mediators.

J Cell Mol Med 2017 10 26;21(10):2573-2585. Epub 2017 Apr 26.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.

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http://dx.doi.org/10.1111/jcmm.13178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618684PMC
October 2017

Synergistic Effect of TPD7 and Berberine against Leukemia Jurkat Cell Growth through Regulating Ephrin-B2 Signaling.

Phytother Res 2017 Sep 12;31(9):1392-1399. Epub 2017 Jul 12.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, No. 76, Yanta West Street, #54, Xi'an, Shaanxi, China.

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http://dx.doi.org/10.1002/ptr.5866DOI Listing
September 2017

Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.

Mol Med Rep 2017 Aug 6;16(2):1369-1375. Epub 2017 Jun 6.

Translational Medicine Center, Hong‑Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi 710054, P.R. China.

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https://www.spandidos-publications.com/10.3892/mmr.2017.6698
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http://dx.doi.org/10.3892/mmr.2017.6698DOI Listing
August 2017

QSAR modeling and in silico design of small-molecule inhibitors targeting the interaction between E3 ligase VHL and HIF-1α.

Mol Divers 2017 08 8;21(3):719-739. Epub 2017 Jul 8.

Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, China.

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http://dx.doi.org/10.1007/s11030-017-9750-yDOI Listing
August 2017

Improving the Catalytic Behavior of DFA I-Forming Inulin Fructotransferase from Streptomyces davawensis with Site-Directed Mutagenesis.

J Agric Food Chem 2017 Aug 17;65(34):7579-7587. Epub 2017 Aug 17.

State Key Laboratory of Food Science and Technology, Jiangnan University , Wuxi, Jiangsu 214122, China.

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http://dx.doi.org/10.1021/acs.jafc.7b02897DOI Listing
August 2017

[Analysis of genotype and phenotype correlation of MYH7-V878A mutation among ethnic Han Chinese pedigrees affected with hypertrophic cardiomyopathy].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2017 Aug;34(4):514-518

Department of Ultrasonography, the First Affiliated Hospital, the Fourth Military Medical University, Xi'an, Shaanxi 710032, China.

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http://dx.doi.org/10.3760/cma.j.issn.1003-9406.2017.04.010DOI Listing
August 2017

A Rare Case of Thoracoschisis.

J Neonatal Surg 2017 Jul-Sep;6(3):65. Epub 2017 Aug 10.

Department of Surgery, University of Illinois at Chicago, 840 S. Wood Street, Suite 416, Chicago, IL, 60612, USA.

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http://dx.doi.org/10.21699/jns.v6i3.581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593484PMC
August 2017

Potent Pan-Raf and Receptor Tyrosine Kinase Inhibitors Based on a Cyclopropyl Formamide Fragment Overcome Resistance.

J Chem Inf Model 2017 06 19;57(6):1439-1452. Epub 2017 May 19.

School of Basic Science, China Pharmaceutical University , 639 Longmian Avenue, Nanjing, Jiangsu 211198, China.

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http://dx.doi.org/10.1021/acs.jcim.6b00795DOI Listing
June 2017

Determine equilibrium dissociation constant of drug-membrane receptor affinity using the cell membrane chromatography relative standard method.

J Chromatogr A 2017 Jun 27;1503:12-20. Epub 2017 Apr 27.

School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2017.04.053DOI Listing
June 2017

Rational design, synthesis, and biological evaluation of Pan-Raf inhibitors to overcome resistance.

Org Biomol Chem 2017 Apr;15(16):3455-3465

School of Basic Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, Jiangsu 211198, China.

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http://dx.doi.org/10.1039/c7ob00518kDOI Listing
April 2017

Taspine derivative 12k suppressed A549 cell migration through the Wnt/β-catenin and EphrinB2 signaling pathway.

Biomed Pharmacother 2017 Mar 31;87:102-109. Epub 2016 Dec 31.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2016.12.077DOI Listing
March 2017

Berberine inhibits the proliferation and migration of breast cancer ZR-75-30 cells by targeting Ephrin-B2.

Phytomedicine 2017 Feb 22;25:45-51. Epub 2016 Dec 22.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, No. 76, Yanta Weststreet, #54, Xi'an, Shaanxi Province 710061, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2016.12.013DOI Listing
February 2017

Nutrients structure changes impact the competition and succession between diatom and dinoflagellate in the East China Sea.

Sci Total Environ 2017 Jan 14;574:499-508. Epub 2016 Oct 14.

Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, Ocean University of China, 266100, PR China; College of Chemistry and Chemical Engineering, Ocean University of China, 266100, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.scitotenv.2016.09.092DOI Listing
January 2017

Electrodeposited reduced graphene oxide incorporating polymerization of l-lysine on electrode surface and its application in simultaneous electrochemical determination of ascorbic acid, dopamine and uric acid.

Mater Sci Eng C Mater Biol Appl 2017 Jan 31;70(Pt 1):241-249. Epub 2016 Aug 31.

School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China; National-Provincial Joint Engineering Research Center for Natural Vascular Medicine Screening & Analysis, Xi'an 710061, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09284931163105
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http://dx.doi.org/10.1016/j.msec.2016.08.078DOI Listing
January 2017

DNA-affibody nanoparticles for inhibiting breast cancer cells overexpressing HER2.

Chem Commun (Camb) 2017 01;53(3):573-576

Biodesign Center for BioEnergetics, Arizona State University, Tempe 85287, USA.

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http://dx.doi.org/10.1039/c6cc08495hDOI Listing
January 2017

A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway.

Oncol Rep 2016 Sep 21;36(3):1526-34. Epub 2016 Jul 21.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.

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http://dx.doi.org/10.3892/or.2016.4960DOI Listing
September 2016

Identification of Covalent Binding Sites Targeting Cysteines Based on Computational Approaches.

Mol Pharm 2016 09 10;13(9):3106-18. Epub 2016 Aug 10.

Laboratory of Molecular Design and Drug Discovery, School of Science, China Pharmaceutical University , 639 Longmian Avenue, Nanjing 211198, China.

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http://dx.doi.org/10.1021/acs.molpharmaceut.6b00302DOI Listing
September 2016

Mitochondrial Nitroreductase Activity Enables Selective Imaging and Therapeutic Targeting.

J Am Chem Soc 2016 09 7;138(37):12009-12. Epub 2016 Sep 7.

Biodesign Center for BioEnergetics, and School of Molecular Sciences, Arizona State University , Tempe, Arizona 85287, United States.

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http://dx.doi.org/10.1021/jacs.6b06229DOI Listing
September 2016

Functional and mechanistic analysis of telomerase: An antitumor drug target.

Pharmacol Ther 2016 07 23;163:24-47. Epub 2016 Apr 23.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi Province 710061, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2016.03.017DOI Listing
July 2016

Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4.

Cell Rep 2016 07 23;16(2):323-332. Epub 2016 Jun 23.

Department of Pharmacology, University of Illinois College of Medicine, Chicago, IL 60612, USA; Division of Cardiology, Department of Medicine, University of Illinois College of Medicine, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.05.089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945388PMC
July 2016

Targeting epigenetic reader and eraser: Rational design, synthesis and in vitro evaluation of dimethylisoxazoles derivatives as BRD4/HDAC dual inhibitors.

Bioorg Med Chem Lett 2016 06 22;26(12):2931-2935. Epub 2016 Apr 22.

Laboratory of Molecular Design and Drug Discovery, School of Science, 639 Longmian Avenue, Nanjing 211198, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.04.034DOI Listing
June 2016

Selective Functionalization of Antimycin A Through an N-Transacylation Reaction.

Org Lett 2016 05 11;18(10):2395-8. Epub 2016 May 11.

Biodesign Center for BioEnergetics and School of Molecular Sciences, Arizona State University , Tempe, Arizona 85287, United States.

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http://dx.doi.org/10.1021/acs.orglett.6b00882DOI Listing
May 2016

Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways.

Mol Med Rep 2016 Apr 19;13(4):3009-16. Epub 2016 Feb 19.

Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China.

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http://dx.doi.org/10.3892/mmr.2016.4917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805065PMC
April 2016

[The relationship between mRNA level of glucocorticoid receptor α, heat shock protein 90, protein level of macrophage migration inhibitory factor and glucocorticoid resistance in systemic lupus erythematosus].

Zhonghua Nei Ke Za Zhi 2015 Nov;54(11):922-6

Department of Rheumatology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.

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November 2015

[Comparison of relevant indicators of coagulation and fibrinolysis in patients with varying severity of community-acquired pneumonia].

Zhonghua Yi Xue Za Zhi 2015 Jun;95(24):1925-9

Department of Respiratory Medicine, Affiliated Hospital, Chengde Medical College, Chengde 067000, China; Email:

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June 2015