Publications

Real-time monitoring of methane oxidation in a simulated landfill cover soil and MiSeq pyrosequencing analysis of the related bacterial community structure.
Waste Manag 2017 May 19. Epub 2017 May 19.
Environmental Microbiology and Ecology Research Center, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Science (CAS), Chongqing 400714, China. Electronic address:

Assessment of relationship on excess arsenic intake from drinking water and cognitive impairment in adults and elders in arsenicosis areas.
Int J Hyg Environ Health 2017 Apr 8;220(2 Pt B):424-430. Epub 2016 Dec 8.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Key lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health, China and Russia Medical Research Center, Harbin Medical University, 157 Baojian Road, Harbin, 150081, China. Electronic address:

Cost-Effectiveness Comparison Between the Response-Guided Therapies and Monotherapies of Nucleos(t)ide Analogues for Chronic Hepatitis B Patients in China.
Clin Drug Investig 2017 Mar;37(3):233-247
Department of Epidemiology and Biostatistics, School of Public Health, Guangdong Pharmaceutical University, No. 283, Jianghai Avenue, Haizhu District, Guangzhou, 510310, Guangdong Province, China.

Matrix Metallopeptidase-2 Gene rs2287074 Polymorphism is Associated with Brick Tea Skeletal Fluorosis in Tibetans and Kazaks, China.
Sci Rep 2017 Jan 12;7:40086. Epub 2017 Jan 12.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin 150081, Heilongjiang Province, China.

Mechanisms Underlying Endothelin-1 Level Elevations Caused by Excessive Fluoride Exposure.
Cell Physiol Biochem 2016 7;40(5):861-873. Epub 2016 Dec 7.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University; Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618504), Harbin, China.

Association between vitamin D receptor gene FokI polymorphism and skeletal fluorosis of the brick-tea type fluorosis: a cross sectional, case control study.
BMJ Open 2016 Nov 10;6(11):e011980. Epub 2016 Nov 10.
Centre for Endemic Disease Control, Chinese Centre for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang, China.

Relationship between fluoride exposure and osteoclast markers during RANKL-induced osteoclast differentiation.
Environ Toxicol Pharmacol 2016 Sep 2;46:241-5. Epub 2016 Aug 2.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618504), Harbin 150081, Heilongjiang Province, China. Electronic address:

Cognitive Impairment and Risk Factors in Elderly People Living in Fluorosis Areas in China.
Biol Trace Elem Res 2016 Jul 25;172(1):53-60. Epub 2015 Nov 25.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618504), China and Russia Medical Research Center, Harbin Medical University, 157 Baojian Road, Harbin, 150081, China.

Role of PTEN-Akt-CREB Signaling Pathway in Nervous System impairment of Rats with Chronic Arsenite Exposure.
Biol Trace Elem Res 2016 Apr 23;170(2):366-72. Epub 2015 Aug 23.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Key Lab of Etiologic Epidemiology of Ministry of Health and Education Bureau of Heilongjiang Province(23618504), Harbin Medical University, 157 Baojian Road, Harbin, 150081, China.

Cost-effectiveness comparison of lamivudine plus adefovir combination treatment and nucleos(t)ide analog monotherapies in Chinese chronic hepatitis B patients.
Drug Des Devel Ther 2016 1;10:897-910. Epub 2016 Mar 1.
Department of Epidemiology and Biostatistics, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, Guangdong, People's Republic of China.

Resveratrol Ameliorates Cardiac Hypertrophy by Down-regulation of miR-155 Through Activation of Breast Cancer Type 1 Susceptibility Protein.
J Am Heart Assoc 2016 Apr 22;5(4). Epub 2016 Apr 22.
Department of Cardiology, The Fourth Hospital of Harbin Medical University, Nangang District Harbin, Heilongjiang, China Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China

A sensitive LC-MS/MS method to quantify methylergonovine in human plasma and its application to a pharmacokinetic study.
J Chromatogr B Analyt Technol Biomed Life Sci 2016 Feb 28;1011:62-8. Epub 2015 Dec 28.
School of Pharmaceutical Sciences of Shandong University, No. 44 West Wenhua Road, Jinan 250012 China; Department of Natural Products Chemistry, Key Lab of Chemical Biology of Ministry of Education, Shandong University, No. 44 West Wenhua Road, Jinan 250012, China. Electronic address:

Intra-individual variation in urinary iodine concentration: effect of statistical correction on population distribution using seasonal three-consecutive-day spot urine in children.
BMJ Open 2016 Feb 26;6(2):e010217. Epub 2016 Feb 26.
Key Laboratory of Etiology and Epidemiology, Education Bureau of Heilongjiang Province and Ministry of Health, Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, People's Republic of China.

Lichen endophyte derived pyridoxatin inactivates Candida growth by interfering with ergosterol biosynthesis.
Biochim Biophys Acta 2015 Sep 8;1850(9):1762-71. Epub 2015 May 8.
Department of Natural Product Chemistry, Key Lab of Chemical Biology of Ministry of Education, Shandong University, No. 44 West Wenhua Road, Jinan City, Shandong Province, China. Electronic address:

Modifying Role of GSTP1 Polymorphism on the Association between Tea Fluoride Exposure and the Brick-Tea Type Fluorosis.
PLoS One 2015 5;10(6):e0128280. Epub 2015 Jun 5.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618504), Harbin 150081, Heilongjiang Province, China.

ent-Kaurane Diterpenoids from Chinese Liverworts and Their Antitumor Activities through Michael Addition As Detected in Situ by a Fluorescence Probe.
J Med Chem 2015 May 21;58(9):3944-56. Epub 2015 Apr 21.
†Department of Natural Products Chemistry, Key Laboratory of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Shandong University, No. 44 West Wenhua Road, Jinan 250012, People's Republic of China.

Iodine deficiency and excess coexist in china and induce thyroid dysfunction and disease: a cross-sectional study.
PLoS One 2014 6;9(11):e111937. Epub 2014 Nov 6.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University; Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618504), Harbin, China.

Effect of high fluoride and high fat on serum lipid levels and oxidative stress in rabbits.
Environ Toxicol Pharmacol 2014 Nov 5;38(3):1000-6. Epub 2014 Nov 5.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, China; Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618504), Harbin, China. Electronic address:

Fluoride decreased osteoclastic bone resorption through the inhibition of NFATc1 gene expression.
Environ Toxicol 2014 May 19;29(5):588-95. Epub 2012 May 19.
Key Laboratory of Etiologic Epidemiology, Ministry of Health (23618104), Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin 150081, Heilongjiang Province, People's Republic of China, >

p38 and extracellular signal-regulated kinases activations have opposite effects on primary-cultured rat cerebellar granule neurons exposed to sodium arsenite.
J Biochem Mol Toxicol 2014 Apr 19;28(4):143-8. Epub 2013 Dec 19.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province and Ministry of Health, Harbin, 150081, People's Republic of China.

Assessment of relationship on excess fluoride intake from drinking water and carotid atherosclerosis development in adults in fluoride endemic areas, China.
Int J Hyg Environ Health 2014 Mar 14;217(2-3):413-20. Epub 2013 Aug 14.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin 150081, China; Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618104), Harbin 150081, China. Electronic address:

Variants in the 5'-upstream region of GPC5 confer risk of lung cancer in never smokers.
Cancer Epidemiol 2014 Feb 20;38(1):66-72. Epub 2014 Jan 20.
Department of Epidemiology and Biostatistics and MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:

Urinary arsenic metabolism in a Western Chinese population exposed to high-dose inorganic arsenic in drinking water: influence of ethnicity and genetic polymorphisms.
Toxicol Appl Pharmacol 2014 Jan 15;274(1):117-23. Epub 2013 Nov 15.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Hei Long Jiang Province & Ministry of Health (23618104), Harbin 150081, China. Electronic address:

Neuroglobin involvement in the course of arsenic toxicity in rat cerebellar granule neurons.
Biol Trace Elem Res 2013 Dec 24;155(3):439-46. Epub 2013 Sep 24.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618104), Harbin Medical University, 157# Baojian Road, Harbin, 150081, People's Republic of China.

Biomarkers of renal toxicity caused by exposure to arsenic in drinking water.
Environ Toxicol Pharmacol 2013 May 19;35(3):495-501. Epub 2013 Feb 19.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of HeiLong Jiang Province & Ministry of Health (23618104), Harbin 150081, China.

A national cross-sectional study on effects of fluoride-safe water supply on the prevalence of fluorosis in China.
BMJ Open 2012 25;2(5). Epub 2012 Sep 25.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University; Key Lab of Etiology and Epidemiology, Education Bureau of Hei Long Jiang Province & Ministry of Health (23618104), Harbin 150081, China.

Changes in serum thioredoxin among individuals chronically exposed to arsenic in drinking water.
Toxicol Appl Pharmacol 2012 Feb 22;259(1):124-32. Epub 2011 Dec 22.
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Hei Long Jiang Province & Ministry of Health (23618104), Harbin 150081, China.

OF