Yang-ja Lee

Yang-ja Lee

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Yang-ja Lee

Yang-ja Lee

Publications by authors named "Yang-ja Lee"

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Drugging SUMOylation for neuroprotection and oncotherapy.

Neural Regen Res 2018 Mar;13(3):415-416

Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health (NINDS/NIH), Bethesda, MD, USA.

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http://dx.doi.org/10.4103/1673-5374.228718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900498PMC
March 2018

SUMOylation in brain ischemia: Patterns, targets, and translational implications.

J Cereb Blood Flow Metab 2018 01 17;38(1):5-16. Epub 2017 Nov 17.

3 Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1177/0271678X17742260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757445PMC
January 2018

Cerebral Ischemia Increases Small Ubiquitin-Like Modifier Conjugation within Human Penumbral Tissue: Radiological-Pathological Correlation.

Front Neurol 2017 12;8:738. Epub 2018 Jan 12.

Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.

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http://dx.doi.org/10.3389/fneur.2017.00738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770374PMC
January 2018

Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels.

Front Mol Neurosci 2018 30;11:22. Epub 2018 Jan 30.

Clinical Investigation Section, Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health (NINDS/NIH), Bethesda, MD, United States.

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http://dx.doi.org/10.3389/fnmol.2018.00022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797618PMC
January 2018

Neural stem cell transplantation in ischemic stroke: A role for preconditioning and cellular engineering.

J Cereb Blood Flow Metab 2017 Jul 17;37(7):2314-2319. Epub 2017 Mar 17.

2 Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health (NINDS/NIH), Bethesda, MD, USA.

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http://dx.doi.org/10.1177/0271678X17700432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531358PMC
July 2017

Global SUMOylation facilitates the multimodal neuroprotection afforded by quercetin against the deleterious effects of oxygen/glucose deprivation and the restoration of oxygen/glucose.

J Neurochem 2016 07 6;138(1):101-16. Epub 2016 Jun 6.

Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health (NINDS/NIH), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1111/jnc.13643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916017PMC
July 2016

Hypophosphorylation of ribosomal protein S6 is a molecular mechanism underlying ischemic tolerance induced by either hibernation or preconditioning.

J Neurochem 2015 Dec 22;135(5):943-57. Epub 2015 Oct 22.

Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1111/jnc.13368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715778PMC
December 2015

Global SUMOylation is a molecular mechanism underlying hypothermia-induced ischemic tolerance.

Front Cell Neurosci 2014 4;8:416. Epub 2014 Dec 4.

Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health Bethesda, MD, USA.

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http://dx.doi.org/10.3389/fncel.2014.00416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255597PMC
December 2014

SUMO and ischemic tolerance.

Neuromolecular Med 2013 Dec 18;15(4):771-81. Epub 2013 Jun 18.

Stroke Branch, National Institute of Neurological Disease and Stroke, National Institutes of Health (NINDS/NIH), Bldg10/Rm5B06, MSC 1401, 10 Center Drive, Bethesda, MD, 20892, USA,

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http://dx.doi.org/10.1007/s12017-013-8239-9DOI Listing
December 2013

Global protein conjugation by ubiquitin-like-modifiers during ischemic stress is regulated by microRNAs and confers robust tolerance to ischemia.

PLoS One 2012 18;7(10):e47787. Epub 2012 Oct 18.

Stroke Branch, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047787PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475703PMC
April 2013

A method for hypothermia-induction and maintenance allows precise body and brain temperature control in mice.

J Neurosci Methods 2013 Feb 19;213(1):1-5. Epub 2012 Nov 19.

Clinical Investigations Section, Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2012.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570728PMC
February 2013

Elevated global SUMOylation in Ubc9 transgenic mice protects their brains against focal cerebral ischemic damage.

PLoS One 2011 7;6(10):e25852. Epub 2011 Oct 7.

Stroke Branch, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025852PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189225PMC
February 2012

SUMOylation participates in induction of ischemic tolerance.

J Neurochem 2009 Apr 5;109(1):257-67. Epub 2009 Feb 5.

Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2009.05957.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692380PMC
April 2009

Protein SUMOylation is massively increased in hibernation torpor and is critical for the cytoprotection provided by ischemic preconditioning and hypothermia in SHSY5Y cells.

J Cereb Blood Flow Metab 2007 May 6;27(5):950-62. Epub 2006 Sep 6.

Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health (NIH), Bethesda, Maryland 20892-4476, USA.

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http://journals.sagepub.com/doi/10.1038/sj.jcbfm.9600395
Publisher Site
http://dx.doi.org/10.1038/sj.jcbfm.9600395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396349PMC
May 2007

Release of OPA1 during apoptosis participates in the rapid and complete release of cytochrome c and subsequent mitochondrial fragmentation.

J Biol Chem 2005 Oct 22;280(42):35742-50. Epub 2005 Aug 22.

Cellular Neurology Unit, Surgical Neurology Branch, NINDS, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1074/jbc.M505970200DOI Listing
October 2005

Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis.

Mol Biol Cell 2004 Nov 8;15(11):5001-11. Epub 2004 Sep 8.

Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.molbiolcell.org/content/15/11/5001.full.pdf
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http://www.molbiolcell.org/cgi/doi/10.1091/mbc.E04-04-0294
Publisher Site
http://dx.doi.org/10.1091/mbc.e04-04-0294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC524759PMC
November 2004

Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers.

EMBO J 2004 May 6;23(10):2146-55. Epub 2004 May 6.

Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1414, USA.

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http://dx.doi.org/10.1038/sj.emboj.7600225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC424420PMC
May 2004

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis.

J Cell Biol 2002 Dec 23;159(6):931-8. Epub 2002 Dec 23.

Biochemistry Section, SNB, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.jcb.org/lookup/doi/10.1083/jcb.200209124
Publisher Site
http://dx.doi.org/10.1083/jcb.200209124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173996PMC
December 2002