Yong Loo Lin School of Medicine (Y.Z., L.T.), National University of Singapore, Singapore; Ocular Surface Research Group (A.V., S.Y., L.T.), Singapore Eye Research Institute; University of Alabama School of Medicine at UAB (D.M.R.), Birmingham, AL; School of Biomedical Engineering (R.U.A., J.H.T.), Ngee Ann Polytechnic, Singapore; Singapore National Eye Center (L.T.); and Duke-NUS Graduate Medical School (L.T.), Singapore.
Cont Lens Anterior Eye 2015 Oct 5;38(5):368-72. Epub 2015 May 5.
Ocular Surface Research Group, Singapore Eye Research Institute, Singapore 168751, Singapore; Department of Cornea and External Eye Disease, Singapore National Eye Center, 11 Third Hospital Avenue, Singapore 168751, Singapore; Office of Clinical, Academic and Faculty Affairs, Duke-NUS Graduate Medical School, Singapore 169857, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, 119228, Singapore.
Dry eye is the most common post-operative complication in patients who undergo laser-assisted in situ keratomileusis and other photorefractive procedures. Epidemiological studies have found that almost all patients experience some form of dry-eye-related discomfort in the post-operative period. This review seeks primarily to identify patient factors, which predispose to this complication, as well as outline the possible interventions clinicians can consider to avoid, prevent and treat this complication. Numerous pre-, intra- and post-operative guidelines are provided. The ideal method of post-laser-assisted in situ keratomileusis dry eye prevention is a meticulous peri-operative management plan, as opposed to post-operative management alone. Newer modalities of photorefractive surgery may have differing effects on the ocular surface.