Yajing Liu

Yajing Liu

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PET probe with Aggregation Induced Emission characteristics for the specific turn-on of aromatase.

Talanta 2020 Feb 1;208:120412. Epub 2019 Oct 1.

Beijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, China. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2019.120412DOI Listing
February 2020

Periostin reverses high glucose-inhibited osteogenesis of periodontal ligament stem cells via AKT pathway.

Life Sci 2020 Feb 21;242:117184. Epub 2019 Dec 21.

Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China; Department of Dental Implantology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2019.117184DOI Listing
February 2020

Optimization of biaryloxazolidinone as promising antibacterial agents against antibiotic-susceptible and antibiotic-resistant gram-positive bacteria.

Eur J Med Chem 2020 Jan 14;185:111781. Epub 2019 Oct 14.

Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang, 110016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.111781DOI Listing
January 2020

Melatonin promotes the development of immature oocytes from the COH cycle into healthy offspring by protecting mitochondrial function.

J Pineal Res 2020 Jan 28;68(1):e12621. Epub 2019 Nov 28.

Department of Obstetrics and Gynecology, Reproductive Medicine Center, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

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http://dx.doi.org/10.1111/jpi.12621DOI Listing
January 2020

Design, Synthesis and Biological Evaluation of Novel 4-phenoxypyridine Derivatives Containing Semicarbazones Moiety as Potential c-Met Kinase Inhibitors.

Anticancer Agents Med Chem 2020 Jan 1. Epub 2020 Jan 1.

College of Pharmacy, Key Laboratory of New Drug Research and Development of Liaoning Province, Liaoning University, Shenyang 110036. China.

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http://dx.doi.org/10.2174/1871520620666200101143307DOI Listing
January 2020

Synthesis and biological evaluation of [F](2S,4S)4-(3-fluoropropyl) arginine as a tumor imaging agent.

Eur J Med Chem 2019 Dec 22;183:111730. Epub 2019 Sep 22.

Beijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.111730DOI Listing
December 2019

Discovery of 4-piperazinyl-2-aminopyrimidine derivatives as dual inhibitors of JAK2 and FLT3.

Eur J Med Chem 2019 Nov 7;181:111590. Epub 2019 Aug 7.

Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, 110016, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234193072
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http://dx.doi.org/10.1016/j.ejmech.2019.111590DOI Listing
November 2019

An improved preparation of [ F]AV-45 by simplified solid-phase extraction purification.

J Labelled Comp Radiopharm 2019 Nov 7. Epub 2019 Nov 7.

Beijing Institute of Brain Disorders, Capital Medical University, Beijing, P. R. China.

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http://dx.doi.org/10.1002/jlcr.3813DOI Listing
November 2019

Interdisciplinary treatment with implant-supported prostheses for an adolescent with ectodermal dysplasia: A clinical report.

J Prosthet Dent 2019 Nov 18. Epub 2019 Nov 18.

Professor, Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China; Professor, Department of Dental Implantology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.prosdent.2019.07.006DOI Listing
November 2019

Site-directed RNA editing (SDRE): Off-target effects and their countermeasures.

J Genet Genomics 2019 Nov 27. Epub 2019 Nov 27.

School of Life Sciences and Technology, ShanghaiTech University, China; Department of Immunobiology, Yale University School of Medicine, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jgg.2019.11.005DOI Listing
November 2019

Design, synthesis, and biological evaluation of 4-((6,7-dimethoxyquinoline-4-yl)oxy)aniline derivatives as FLT3 inhibitors for the treatment of acute myeloid leukemia.

Bioorg Med Chem Lett 2019 Oct 20;29(19):126630. Epub 2019 Aug 20.

Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.126630DOI Listing
October 2019

High-level expression of lipase from mafic-0601 by codon optimization in and its application in hydrolysis of various oils.

3 Biotech 2019 Oct 4;9(10):354. Epub 2019 Sep 4.

National Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, No.2 Yuanmingyuan West Road, Beijing, 100193 People's Republic of China.

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http://dx.doi.org/10.1007/s13205-019-1891-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726727PMC
October 2019

Biodegradable poly(3-hydroxybutyrate-co-4-hydroxybutyrate) microcapsules for controlled release of trifluralin with improved photostability and herbicidal activity.

Mater Sci Eng C Mater Biol Appl 2019 Sep 16;102:134-141. Epub 2019 Apr 16.

Institute of Plant Protection, Chinese Academy of Agricultural Sciences, No. 2 Yuanmingyuan West Road, Haidian District, Beijing 100193, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.msec.2019.04.050DOI Listing
September 2019

An efficient utilization of chromium-containing vanadium tailings: Extraction of chromium by soda roasting-water leaching and preparation of chromium oxide.

J Environ Manage 2019 Aug 18;244:119-126. Epub 2019 May 18.

School of Metallurgy, Northeastern University, Shenyang, 110819, Liaoning, China; Liaoning Key Laboratory for Recycling Science of Metallurgical Resources, Shenyang, 110819, Liaoning, China.

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http://dx.doi.org/10.1016/j.jenvman.2019.05.037DOI Listing
August 2019

Effects of supplemented culture media from solid-state fermented Isaria cicadae on performance, serum biochemical parameters, serum immune indexes, antioxidant capacity and meat quality of broiler chickens.

Asian-Australas J Anim Sci 2019 Aug 3. Epub 2019 Aug 3.

State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

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http://dx.doi.org/10.5713/ajas.19.0179DOI Listing
August 2019

A multimodal imaging features of the brain in adult-onset neuronal intranuclear inclusion disease.

Neurol Sci 2019 Jul 6;40(7):1495-1497. Epub 2019 Feb 6.

Department of Neurology, Foshan Hospital Affiliated to Sun Yat-sen University, No. 81, Lingnan North Road, Foshan, 528000, Guangdong, China.

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http://dx.doi.org/10.1007/s10072-019-03742-5DOI Listing
July 2019

Multifunctional Magnetic Nanoplatform Eliminates Cancer Stem Cells via Inhibiting the Secretion of Extracellular Heat Shock Protein 90.

Adv Healthc Mater 2019 Jul 10;8(13):e1900160. Epub 2019 Apr 10.

Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding, 071002, P. R. China.

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http://dx.doi.org/10.1002/adhm.201900160DOI Listing
July 2019

Rapid screening of nine unradiolabeled candidate compounds as PET brain imaging agents using cassette-wave microdosing and LC-MS/MS.

J Chromatogr B Analyt Technol Biomed Life Sci 2019 Jul 6;1121:28-38. Epub 2019 May 6.

Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2019.05.006DOI Listing
July 2019

Design, synthesis and biological evaluation of novel aryl-acrylic derivatives as novel indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors.

Bioorg Med Chem 2019 Jul 1;27(14):3135-3144. Epub 2019 Jun 1.

Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.05.048DOI Listing
July 2019

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis.

Nature 2019 07 10;571(7764):275-278. Epub 2019 Jun 10.

Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.1038/s41586-019-1314-0DOI Listing
July 2019

Synthesis and preliminary evaluation of a novel glutamine derivative: (2S,4S)4-[F]FEBGln.

Bioorg Med Chem Lett 2019 May 11;29(9):1047-1050. Epub 2019 Mar 11.

Beijing Institute of Brain Disorders, Capital Medical University, Beijing 100069, China; Department of Radiology, University of Pennsylvania, Philadelphia 19104, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X193014
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http://dx.doi.org/10.1016/j.bmcl.2019.03.012DOI Listing
May 2019

Design, synthesis, and biological evaluation of novel 4-phenoxypyridine derivatives as potential antitumor agents.

Arch Pharm (Weinheim) 2019 May 19;352(5):e1800338. Epub 2019 Mar 19.

Key Laboratory of New Drug Research and Development of Liaoning Province, College of Pharmacy Liaoning University, Shenyang, P. R. China.

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http://dx.doi.org/10.1002/ardp.201800338DOI Listing
May 2019

Discovery of [1,2,4]Triazolo[4,3- a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.

J Med Chem 2019 May 19;62(9):4703-4715. Epub 2019 Apr 19.

Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) , Ministry of Education , 103 Wenhua Road , Shenyang 110016 , PR China.

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http://dx.doi.org/10.1021/acs.jmedchem.9b00312DOI Listing
May 2019

Correction to: A multimodal imaging features of the brain in adult-onset neuronal intranuclear inclusion disease.

Neurol Sci 2019 Apr;40(4):905

Department of Neurology, Foshan Hospital Affiliated to Sun Yat-sen University, No. 81, Lingnan North Road, Foshan, 528000, Guangdong, China.

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http://dx.doi.org/10.1007/s10072-019-03787-6DOI Listing
April 2019

NLRP3 inflammasome plays an important role in caspase-1 activation and IL-1β secretion in macrophages infected with Pasteurella multocida.

Vet Microbiol 2019 Apr 18;231:207-213. Epub 2019 Mar 18.

College of Animal Science and Technology, Southwest University, Chongqing, 400715, China. Electronic address:

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http://dx.doi.org/10.1016/j.vetmic.2019.03.019DOI Listing
April 2019

Aggregation-Induced Absorption Enhancement for Deep Near-Infrared II Photoacoustic Imaging of Brain Gliomas In Vivo.

Adv Sci (Weinh) 2019 Apr 16;6(8):1801615. Epub 2019 Jan 16.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine School of Public Health Xiamen University Xiamen 361102 China.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.2018016
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http://dx.doi.org/10.1002/advs.201801615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469237PMC
April 2019

Metabonomics analysis of kidneys in rats administered with chronic low-dose cadmium by ultra-performance liquid chromatography-mass spectrometry.

J Appl Toxicol 2019 Mar 16;39(3):441-450. Epub 2018 Oct 16.

Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, Heilongjiang, China.

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http://doi.wiley.com/10.1002/jat.3735
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http://dx.doi.org/10.1002/jat.3735DOI Listing
March 2019

In Vivo Ester Hydrolysis as a New Approach in Development of Positron Emission Tomography Tracers for Imaging Hypoxia.

Mol Pharm 2019 03 20;16(3):1156-1166. Epub 2019 Feb 20.

Beijing Institute for Brain Disorders , Capital Medical University , Beijing 100069 , P. R. China.

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http://dx.doi.org/10.1021/acs.molpharmaceut.8b01131DOI Listing
March 2019

Design, synthesis and biological evaluation of novel 7-amino-[1,2,4]triazolo[4,3-f]pteridinone, and 7-aminotetrazolo[1,5-f]pteridinone derivative as potent antitumor agents.

Eur J Med Chem 2019 Feb 10;163:690-709. Epub 2018 Dec 10.

Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, 110016, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.12.009DOI Listing
February 2019

Gemfibrozil reduces lipid accumulation in SMMC-7721 cells via the involvement of PPARα and SREBP1.

Exp Ther Med 2019 Feb 5;17(2):1282-1289. Epub 2018 Dec 5.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, P.R. China.

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http://dx.doi.org/10.3892/etm.2018.7046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327679PMC
February 2019

β-xylosidase and β-mannosidase in combination improved growth performance and altered microbial profiles in weanling pigs fed a corn-soybean meal-based diet.

Asian-Australas J Anim Sci 2019 Feb 14:1734-1744. Epub 2019 Feb 14.

State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

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http://dx.doi.org/10.5713/ajas.18.0873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817776PMC
February 2019

Trivalent Chromium Supplementation Ameliorates Oleic Acid-Induced Hepatic Steatosis in Mice.

Biol Trace Elem Res 2019 Jan 24;187(1):192-201. Epub 2018 May 24.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.

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http://dx.doi.org/10.1007/s12011-018-1368-0DOI Listing
January 2019

miR-323-3p regulates the steroidogenesis and cell apoptosis in polycystic ovary syndrome (PCOS) by targeting IGF-1.

Gene 2019 Jan 6;683:87-100. Epub 2018 Oct 6.

Reproductive Medicine Center, Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Anhui Province Key Laboratory of Reproductive Health and Genetics, Biopreservation and Artificial Organs, Anhui Provincial Engineering Research Center, Anhui Medical University, Hefei, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03781119183103
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http://dx.doi.org/10.1016/j.gene.2018.10.006DOI Listing
January 2019

AMPK activators contribute to maintain naïve pluripotency in mouse embryonic stem cells.

Biochem Biophys Res Commun 2019 01 17;509(1):24-31. Epub 2018 Dec 17.

The Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.11.164DOI Listing
January 2019

Synthesis and Properties of 3-Azido-2,2-bis(azidomethyl)propyl 2-Azidoacetate: A Potential Azido Ester Plasticizer.

Chempluschem 2019 Jan;84(1):107-111

Applied Chemistry, Xi'an Modern Chemistry Research Institute, Zhangbadonglu 168, Xi'an, Shanxi, 710065, P. R. China.

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http://dx.doi.org/10.1002/cplu.201800531DOI Listing
January 2019

Soybean CCA1-like MYB transcription factor GmMYB133 modulates isoflavonoid biosynthesis.

Biochem Biophys Res Commun 2018 12 15;507(1-4):324-329. Epub 2018 Nov 15.

College of Plant Science, Jilin University, Changchun, 130062, Jilin, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X183243
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http://dx.doi.org/10.1016/j.bbrc.2018.11.033DOI Listing
December 2018

Metabonomics analysis of quercetin against the nephrotoxicity of acrylamide in rats.

Food Funct 2018 Nov;9(11):5965-5974

Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, Heilongjiang, China.

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http://xlink.rsc.org/?DOI=C8FO00902C
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http://dx.doi.org/10.1039/c8fo00902cDOI Listing
November 2018

Two-photon fluorescent probe for detection of nitroreductase and hypoxia-specific microenvironment of cancer stem cell.

Anal Chim Acta 2018 Sep 29;1024:177-186. Epub 2018 Mar 29.

Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding, 071002, China; College of Chemistry and Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding, 071002, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00032670183040
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http://dx.doi.org/10.1016/j.aca.2018.03.030DOI Listing
September 2018

Morphology Tuning of Aggregation-Induced Emission Probes by Flash Nanoprecipitation: Shape and Size Effects on in Vivo Imaging.

ACS Appl Mater Interfaces 2018 Aug 18;10(30):25186-25193. Epub 2018 Jul 18.

Engineering Research Center of Materials Chemical Engineering of Xinjiang Bingtuan , Shihezi University , Xinjiang 832000 , P. R. China.

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http://dx.doi.org/10.1021/acsami.8b08159DOI Listing
August 2018

A sequence-activated AND logic dual-channel fluorescent probe for tracking programmable drug release.

Chem Sci 2018 Aug 22;9(29):6176-6182. Epub 2018 Jun 22.

Key Laboratory for Advanced Materials and Institute of Fine Chemicals , Shanghai Key Laboratory of Functional Materials Chemistry , School of Chemistry and Molecular Engineering , East China University of Science and Technology , Shanghai , 200237 , China . Email: ; Email:

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http://dx.doi.org/10.1039/c8sc02079eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062889PMC
August 2018

Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing.

Nat Commun 2018 06 14;9(1):2338. Epub 2018 Jun 14.

School of Life Science and Technology, ShanghaiTech University, 100 Haike Road, Pudong New Area, 201210, Shanghai, China.

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http://dx.doi.org/10.1038/s41467-018-04768-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002399PMC
June 2018

Discovery of selective EGFR modulator to inhibit L858R/T790M double mutants bearing a N-9-Diphenyl-9H-purin-2-amine scaffold.

Bioorg Med Chem 2018 05 17;26(8):1810-1822. Epub 2018 Feb 17.

Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2018.02.029DOI Listing
May 2018

Developing a cassette microdosing approach to enhance the throughput of PET imaging agent screening.

J Pharm Biomed Anal 2018 May 3;154:48-56. Epub 2018 Mar 3.

Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2018.02.063DOI Listing
May 2018

Design, synthesis, and structure-activity relationships of novel imidazo[4,5-c]pyridine derivatives as potent non-nucleoside inhibitors of hepatitis C virus NS5B.

Bioorg Med Chem 2018 05 16;26(9):2621-2631. Epub 2018 Apr 16.

Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2018.04.029DOI Listing
May 2018

Base editing with a Cpf1-cytidine deaminase fusion.

Nat Biotechnol 2018 04 19;36(4):324-327. Epub 2018 Mar 19.

School of Life Science and Technology, ShanghaiTech University, Shanghai, China.

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http://dx.doi.org/10.1038/nbt.4102DOI Listing
April 2018

Palladium-Catalyzed Cyclization Reaction of Oxime Acetates and Aryl Iodides: Syntheses of 2-Imidazolines.

Org Lett 2018 04 19;20(7):2116-2119. Epub 2018 Mar 19.

Key Laboratory of Structure-based Drug Design and Discovery (Shenyang Pharmaceutical University) , Ministry of Education , 103 Wenhua Road, Shenhe District , Shenyang 110016 , People's Republic of China.

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http://dx.doi.org/10.1021/acs.orglett.8b00696DOI Listing
April 2018

Defect-related luminescent bur-like hydroxyapatite microspheres induced apoptosis of MC3T3-E1 cells by lysosomal and mitochondrial pathways.

Sci China Life Sci 2018 04 30;61(4):464-475. Epub 2018 Mar 30.

College of Chemistry & Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding, 071002, China.

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http://dx.doi.org/10.1007/s11427-017-9258-3DOI Listing
April 2018

MiR-30a-5p confers cisplatin resistance by regulating IGF1R expression in melanoma cells.

BMC Cancer 2018 04 11;18(1):404. Epub 2018 Apr 11.

Biomedical Research Institute, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, No. 1120 Lianhua Road, Futian District, Shenzhen, Guangdong province, China.

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http://dx.doi.org/10.1186/s12885-018-4233-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896053PMC
April 2018

Antidiabetic Activity of Ergosterol from Pleurotus Ostreatus in KK-A Mice with Spontaneous Type 2 Diabetes Mellitus.

Mol Nutr Food Res 2018 02 9;62(3). Epub 2018 Jan 9.

School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, China.

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http://dx.doi.org/10.1002/mnfr.201700444DOI Listing
February 2018

Synthesis and biological evaluation of 4,6-diphenyl-2-(1H-pyrrol-1-yl)nicotinonitrile analogues of crolibulin and combretastatin A-4.

Eur J Med Chem 2018 Feb 4;146:185-193. Epub 2018 Feb 4.

Liaoning Cancer Hospital & Institute, 44 Xiaoheyan Road, Dadong District, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.01.052DOI Listing
February 2018

Synthesis and biological evaluation of 4,6-diphenyl-2-(1H-pyrrol-1-yl)nicotinonitrile analogues of crolibulin and combretastatin A-4.

Eur J Med Chem 2018 Feb 4;146:185-193. Epub 2018 Feb 4.

Liaoning Cancer Hospital & Institute, 44 Xiaoheyan Road, Dadong District, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.01.052DOI Listing
February 2018

Anti-tumour effects of polysaccharide extracted from and cell-mediated immunity.

Exp Ther Med 2018 Feb 27;15(2):1694-1701. Epub 2017 Nov 27.

College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, Jilin 130118, P.R. China.

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http://www.spandidos-publications.com/10.3892/etm.2017.5568
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http://dx.doi.org/10.3892/etm.2017.5568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774378PMC
February 2018

Relationship between glycated haemoglobin concentration and erythrocyte survival in type 2 diabetes mellitus determined by a modified carbon monoxide breath test.

J Breath Res 2018 01 9;12(2):026004. Epub 2018 Jan 9.

Department of Endocrinology, Nanshan Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong 518051, People's Republic of China.

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http://dx.doi.org/10.1088/1752-7163/aa9081DOI Listing
January 2018

Epitranscriptomic mA Regulation of Axon Regeneration in the Adult Mammalian Nervous System.

Neuron 2018 01;97(2):313-325.e6

Department of Neuroscience, Mahoney Institute for Neurosciences, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Biochemistry, Cellular, and Molecular Biology Graduate Program, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Cellular and Molecular Medicine Graduate Program, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.12.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777326PMC
January 2018

A Distinct Endocytic Mechanism of Functionalized-Silica Nanoparticles in Breast Cancer Stem Cells.

Sci Rep 2017 11 24;7(1):16236. Epub 2017 Nov 24.

Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding, 071002, People's Republic of China.

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http://dx.doi.org/10.1038/s41598-017-16591-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701218PMC
November 2017

Versatile pH-response Micelles with High Cell-Penetrating Helical Diblock Copolymers for Photoacoustic Imaging Guided Synergistic Chemo-Photothermal Therapy.

Theranostics 2016 13;6(12):2170-2182. Epub 2016 Sep 13.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.7150/thno.16633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135441PMC
October 2017

Highly efficient and precise base editing in discarded human tripronuclear embryos.

Protein Cell 2017 10;8(10):776-779

Department of Reproductive Medicine, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.

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http://dx.doi.org/10.1007/s13238-017-0458-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636751PMC
October 2017

Pneumolysin-Dependent Calpain Activation and Interleukin-1α Secretion in Macrophages Infected with Streptococcus pneumoniae.

Infect Immun 2017 09 18;85(9). Epub 2017 Aug 18.

Division of Immunology and Molecular Biology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan

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http://dx.doi.org/10.1128/IAI.00201-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563559PMC
September 2017

Isolation and characterization of GmMYBJ3, an R2R3-MYB transcription factor that affects isoflavonoids biosynthesis in soybean.

PLoS One 2017 27;12(6):e0179990. Epub 2017 Jun 27.

Jilin Key Laboratory for Crop Genetic Engineering, College of Plant Science, Jilin University, Changchun, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179990PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487076PMC
September 2017

Ferrocene-Based Hyperbranched Polytriazoles: Synthesis by Click Polymerization and Application as Precursors to Nanostructured Magnetoceramics.

Macromol Rapid Commun 2017 Sep 25;38(17). Epub 2017 Jul 25.

Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.1002/marc.201700075DOI Listing
September 2017

GSH-Activated NIR Fluorescent Prodrug for Podophyllotoxin Delivery.

ACS Appl Mater Interfaces 2017 Sep 25;9(35):29496-29504. Epub 2017 Aug 25.

State Key Laboratory of Bioreactor Engineering, Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology , 130 Meilong Road, Shanghai 200237, PR China.

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http://dx.doi.org/10.1021/acsami.7b07091DOI Listing
September 2017

Design, synthesis and biological evaluation of novel 4-phenoxyquinoline derivatives containing 3-oxo-3,4-dihydroquinoxaline moiety as c-Met kinase inhibitors.

Bioorg Med Chem 2017 08 27;25(16):4475-4486. Epub 2017 Jun 27.

Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.06.037DOI Listing
August 2017

Design, synthesis, and biological activity of novel tetrahydropyrazolopyridone derivatives as FXa inhibitors with potent anticoagulant activity.

Bioorg Med Chem 2017 05 29;25(10):2800-2810. Epub 2017 Mar 29.

Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.03.055DOI Listing
May 2017

Semifluorinated Synergistic Nonfouling/Fouling-Release Surface.

ACS Appl Mater Interfaces 2017 May 2;9(19):16517-16523. Epub 2017 May 2.

Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, People's Republic of China.

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http://dx.doi.org/10.1021/acsami.7b03258DOI Listing
May 2017

Near-infrared fluorescent dyes with large Stokes shifts: light generation in BODIPYs undergoing excited state intramolecular proton transfer.

Org Biomol Chem 2017 May;15(19):4072-4076

Department of Chemistry, School of Science, Tianjin University, Tianjin 300072, China.

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http://dx.doi.org/10.1039/c7ob00383hDOI Listing
May 2017

MACC1 mediates chemotherapy sensitivity of 5-FU and cisplatin via regulating MCT1 expression in gastric cancer.

Biochem Biophys Res Commun 2017 04 21;485(3):665-671. Epub 2017 Feb 21.

Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.02.096DOI Listing
April 2017

ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway.

Mol Cancer 2017 04 13;16(1):79. Epub 2017 Apr 13.

Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.1186/s12943-017-0648-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390360PMC
April 2017

Highly specific noninvasive photoacoustic and positron emission tomography of brain plaque with functionalized croconium dye labeled by a radiotracer.

Chem Sci 2017 Apr 13;8(4):2710-2716. Epub 2017 Jan 13.

State Key Laboratory of Molecular Vaccinology , Molecular Diagnosis & Center for Molecular Imaging and Translational Medicine , School of Public Health , Xiamen University , Xiamen 361102 , People's Republic of China . Email: ; Email:

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http://xlink.rsc.org/?DOI=C6SC04798J
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http://dx.doi.org/10.1039/c6sc04798jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399633PMC
April 2017

RAD51 Mediates Resistance of Cancer Stem Cells to PARP Inhibition in Triple-Negative Breast Cancer.

Clin Cancer Res 2017 Jan 29;23(2):514-522. Epub 2016 Dec 29.

Innovation Center for Cell Signaling Network and the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Science and Medical Center, University of Science and Technology of China, Hefei, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1348DOI Listing
January 2017

Design, synthesis and structure-activity relationships of novel 4-phenoxyquinoline derivatives containing 1,2,4-triazolone moiety as c-Met kinase inhibitors.

Eur J Med Chem 2016 Nov 26;123:431-446. Epub 2016 Jul 26.

Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2016.07.059DOI Listing
November 2016

Design, synthesis, and structure-activity relationship of novel and effective apixaban derivatives as FXa inhibitors containing 1,2,4-triazole/pyrrole derivatives as P2 binding element.

Bioorg Med Chem 2016 11 12;24(21):5646-5661. Epub 2016 Sep 12.

Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.09.024DOI Listing
November 2016

A novel inactivated enterovirus 71 vaccine can elicit cross-protective immunity against coxsackievirus A16 in mice.

Vaccine 2016 11 19;34(48):5938-5945. Epub 2016 Oct 19.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science & School of Public Health, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.1016/j.vaccine.2016.10.018DOI Listing
November 2016

A neonatal mouse model for the evaluation of antibodies and vaccines against coxsackievirus A6.

Antiviral Res 2016 10 28;134:50-57. Epub 2016 Aug 28.

National Institutes for Food and Drug Control, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2016.08.025DOI Listing
October 2016

In Situ Ratiometric Quantitative Tracing of Intracellular Leucine Aminopeptidase Activity via an Activatable Near-Infrared Fluorescent Probe.

ACS Appl Mater Interfaces 2016 Oct 3;8(40):26622-26629. Epub 2016 Oct 3.

State Key Laboratory of Fine Chemicals, Dalian University of Technology , Dalian 116024, P. R. China.

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http://dx.doi.org/10.1021/acsami.6b10238DOI Listing
October 2016

ΔNp63α expression induces loss of cell adhesion in triple-negative breast cancer cells.

BMC Cancer 2016 10 10;16(1):782. Epub 2016 Oct 10.

Regional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Zluty kopec 7, Brno, 65653, Czech Republic.

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http://dx.doi.org/10.1186/s12885-016-2808-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057421PMC
October 2016

Rhizobium anhuiense as the predominant microsymbionts of Lathyrus maritimus along the Shandong Peninsula seashore line.

Syst Appl Microbiol 2016 Sep 20;39(6):384-90. Epub 2016 Jul 20.

Key Laboratory of Coastal Biology and Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, 264003 Yantai, China. Electronic address:

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http://dx.doi.org/10.1016/j.syapm.2016.07.001DOI Listing
September 2016

[Analysis of death risk factors for nosocomial infection patients in an ICU: a retrospective review of 864 patients from 2009 to 2015].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2016 Aug;28(8):704-8

Department of Critical Care Medicine, Harrison International Peace Hospital Affiliated to Hebei Medical University, Hengshui 053000, Hebei, China. Corresponding author: Cui Zhaobo, Email:

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http://dx.doi.org/10.3760/cma.j.issn.2095-4352.2016.08.007DOI Listing
August 2016

Photoacoustic Molecular Imaging: From Multiscale Biomedical Applications Towards Early-Stage Theranostics.

Trends Biotechnol 2016 05 26;34(5):420-433. Epub 2016 Feb 26.

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tibtech.2016.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600199PMC
May 2016

Genetic diversity and community structure of rhizobia nodulating Sesbania cannabina in saline-alkaline soils.

Syst Appl Microbiol 2016 May 17;39(3):195-202. Epub 2016 Mar 17.

Key Laboratory of Coastal Biology and Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, 264003 Yantai, China. Electronic address:

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http://dx.doi.org/10.1016/j.syapm.2016.02.004DOI Listing
May 2016

Development of sandwich ELISAs that can distinguish different types of coxsackievirus A16 viral particles.

Appl Microbiol Biotechnol 2016 Mar 15;100(6):2809-15. Epub 2016 Jan 15.

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, Xiamen University, Xiamen, 361102, China.

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http://dx.doi.org/10.1007/s00253-016-7296-zDOI Listing
March 2016

Construction and characterization of an infectious clone of coxsackievirus A6 that showed high virulence in neonatal mice.

Virus Res 2015 Dec 10;210:165-8. Epub 2015 Aug 10.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, Xiamen University, Xiamen 361102, China; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University, Xiamen 361102, China.

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https://linkinghub.elsevier.com/retrieve/pii/S01681702153003
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http://dx.doi.org/10.1016/j.virusres.2015.08.002DOI Listing
December 2015

Synthesis and Anti-Hepatitis B Virus Evaluation of 7-Methoxy-3-heterocyclic quinolin-6-ols.

Arch Pharm (Weinheim) 2015 Nov 5;348(11):776-785. Epub 2015 Oct 5.

Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, P. R. China.

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http://dx.doi.org/10.1002/ardp.201500238DOI Listing
November 2015

Design and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives bearing an imidazolone moiety as c-Met kinase inhibitors.

Bioorg Med Chem 2015 Aug 17;23(15):4410-22. Epub 2015 Jun 17.

Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, Shenyang 110016, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.06.026DOI Listing
August 2015