Publications by authors named "Yabo Wang"

84 Publications

Trousseau's Syndrome: Be Alert to Short-term Recurrent Cerebral Infarctions and Rapid Death.

J Coll Physicians Surg Pak 2021 Aug;31(8):1009-1010

Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, Shandong, P.R. China.

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http://dx.doi.org/10.29271/jcpsp.2021.08.1009DOI Listing
August 2021

Technical framework for wastewater-based epidemiology of SARS-CoV-2.

Sci Total Environ 2021 Jun 11;791:148271. Epub 2021 Jun 11.

Department of Pharmaceutical & Biological Engineering, School of Chemical Engineering, Sichuan University, Chengdu 610065, China. Electronic address:

Wastewater-based epidemiology (WBE) is expected to become a powerful tool to monitor the dissemination of SARS-CoV-2 at the community level, which has attracted the attention of scholars all over the world. However, there is not yet a standard protocol to guide its implementation. In this paper, we proposed a comprehensive technical and theoretical framework of relative quantification via qPCR for determining the virus abundance in wastewater and estimating the infection ratio in corresponding communities, which is expected to achieve horizontal and vertical comparability of the data using a human-specific biomarker as the internal reference. Critical factors affecting the virus detectability and the estimation of infection ratio include virus concentration methods, lag-period, per capita virus shedding amount, sewage generation rate, temperature-related decay kinetics of virus/biomarker in wastewater, and hydraulic retention time (HRT), etc. Theoretical simulation shows that the main factors affecting the detectability of virus in sewage are per capita virus shedding amount and sewage generation rate. While the decay of SARS-CoV-2 RNA in sewage is a relatively slow process, which may have limited impact on its detection. Under the ideal condition of high per capita virus shedding amount and low sewage generation rate, it is expected to detect a single infected person within 400,000 people.
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http://dx.doi.org/10.1016/j.scitotenv.2021.148271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195746PMC
June 2021

Co-pyrolysis of spent radioactive ion exchange resin and manganese dioxide: Decrease the decomposition temperatures of functional groups.

J Hazard Mater 2021 Jun 1;418:126275. Epub 2021 Jun 1.

Department of Pharmaceutical & Biological Engineering, School of Chemical Engineering, Sichuan University, Chengdu 610065, China. Electronic address:

With the development of the nuclear industry and clean energy, spent radioactive ion exchange resin has become a major concern that needs to be solved urgently. In this study, the mixed resin (sulfonic aid and quaternary ammonium polystyrene beads, 1:2, v/v) is co-pyrolyzed with manganese dioxide in a tube furnace, selecting argon as the reaction atmosphere. Manganese dioxide exhibits unique catalytic and oxidative activity, and a low mass remaining efficiency of 34.14% is obtained under low heating temperature of 300 ℃. The required decomposition temperatures of functional groups and benzene are decreased by approximately 100 ℃, and that of polymer chain is decreased by 130 ℃. The TGA analysis shows the decomposition temperature rule of functional groups and base polymer. The FT-IR spectra and XPS analysis reveal the bridging effects of manganese sulfonate and sulfide group. The SEM diagrams prove that the two processes including depolymerization and reunion could be found in co-pyrolysis. The XRD analysis indicates manganese dioxide undergoes the reduction path of MnO→MnO→MnO, and MnS is formed with the decomposition of manganese sulfonate. The possible mechanism of solid-phase reaction is proposed to explain the promotion of manganese dioxide on co-pyrolysis.
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http://dx.doi.org/10.1016/j.jhazmat.2021.126275DOI Listing
June 2021

Multiple cerebral infarction linked to underlying cancer: a review of Trousseau syndrome-related cerebral infarction.

Br J Hosp Med (Lond) 2021 May 26;82(5):1-7. Epub 2021 May 26.

Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, People's Republic of China.

Trousseau syndrome is a cancer-associated hypercoagulative state leading to venous or arterial thromboembolic events. Cerebral infarction is the most common result of arterial embolism and the pathogenesis is complicated, mainly associated with hypercoagulation and non-bacterial thrombotic endocarditis. On magnetic resonance imaging, multiple lesions are dispersed in more than two territories of the brain, often simultaneously involving the bilateral anterior and posterior circulation. Elevated plasma levels of D-dimer and fibrinogen degradation products may be seen in these patients. There are high rates of short-term recurrence of stroke and sudden death, highlighting the need for early recognition and appropriate treatment of Trousseau syndrome-associated cerebral infarction.
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http://dx.doi.org/10.12968/hmed.2020.0696DOI Listing
May 2021

The risk of ischemic stroke in patients with idiopathic inflammatory myopathies: a systematic review and meta-analysis.

Clin Rheumatol 2021 May 1. Epub 2021 May 1.

Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, No. 5 Donghai Middle Road, Qingdao, Shandong Province, 266071, China.

Objective: Idiopathic inflammatory myopathies (IIM) are a group of chronic rheumatic diseases that can affect multiple systems; the risk of ischemic stroke in patients with IIM remains controversial. We aimed to systematically evaluate the risk of ischemic stroke in IIMs.

Methods: The PubMed, Embase, and Cochrane library were searched for relevant studies. Pooled relative risk (RR) with a 95% confidence interval (CI) was calculated as effect size to evaluate the risk of ischemic stroke in patients with IIM. Random effects model was chosen when I > 50%. We pooled all studies in a first total analysis to assess the risk of ischemic stroke in IIM. Subgroup analyses were conducted based on the subtypes of IIM (dermatomyositis) and country. Sensitivity analysis was performed to identify the heterogeneity sources.

Results: A total of 6 studies with 5,114 IIM cases and 14,516,099 controls were included, and the results demonstrated that IIMs were associated with an increased risk of ischemic stroke (RR = 2.41, 95% CI: 1.31, 4.45). Subgroup analysis indicated that patients with dermatomyositis (DM) had a 49% excess risk of ischemic stroke than controls; Asian patients with IIM had an increased risk of ischemic stroke, although not for American patients.

Conclusion: IIMs, especially patients with DM, are associated with an increased risk of ischemic stroke. Appropriate intervention may be taken into account for patients with IIM, especially when accompanied by other traditional risk factors of ischemic stroke. Key Points • This study evaluated the risk of ischemic stroke in patients with IIMs. • Generally, IIMs are associated with an increased risk of ischemic stroke. • Patients with DM had a 49% excess risk of ischemic stroke than controls. • Subgroup analysis showed that Asian patients with IIMs were at increased risk of ischemic stroke, but not Americans.
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http://dx.doi.org/10.1007/s10067-021-05751-2DOI Listing
May 2021

Significantly boosted oxygen electrocatalysis with cooperation between cobalt and iron porphyrins.

Dalton Trans 2021 Apr;50(15):5120-5123

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710119, China.

Developing electrocatalysts for the oxygen reduction reaction (ORR) and the oxygen evolution reaction (OER) is of great importance. Herein, Co tetrakis(pentafluorophenyl)porphyrin (Co-P) and Fe chloride tetrakis(pentafluorophenyl)porphyrin (Fe-P) were loaded on carbon nanotubes (CNTs) for combining the electrocatalytic advantages of both Co-P and Fe-P. The resultant (Co-P)0.5(Fe-P)[email protected] composite displayed significantly boosted activity for the selective four-electron ORR with a half-wave potential of 0.80 V versus reversible hydrogen electrode (RHE) and for the OER with a potential of 1.65 V versus RHE to obtain 10 mA cm-2 current density in 0.1 M KOH. A Zn-air battery assembled from (Co-P)0.5(Fe-P)[email protected] exhibited a small charge-discharge voltage gap of 0.74 V at 2 mA cm-2, a high power density of 174.5 mW cm-2 and a good rechargeable stability (>120 cycles).
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http://dx.doi.org/10.1039/d1dt00441gDOI Listing
April 2021

LncRNA-MIAT promotes neural cell autophagy and apoptosis in ischemic stroke by up-regulating REDD1.

Brain Res 2021 Jul 18;1763:147436. Epub 2021 Mar 18.

Department of Internal Neurology, Huaihe Hospital of Henan University, Kaifeng 475000, China. Electronic address:

Background: Ischemic stroke (IS) accounts for 80% of stroke incidence, which has an impact on the life quality of patients. Long non-coding RNA (LncRNA), a class of non-coding transcripts greater than 200 nucleotidesin length, has been extensively studied in cerebrovascular diseases. Myocardial infarction associated transcript (MIAT) is highly expressed in nervous system. Therefore this study aims to explore the role of LncRNA MIAT in IS and to clarify its underlying mechanism, providing therapeutic value for the treatment of IS.

Methods: The neurological function of rats was evaluated by neurological deficit score. Triphenyltetrazolium chloride (TTC) staining was used to detect infarct area in brain tissues. Quantitative real-time polymerase chain reaction (qRT-PCR) was performed to examine the expression of MIAT. Western blotting was used to detect the expressions of REDD1, p-mTOR, autophagy-related proteins LC3 and p62, and apoptotic-related proteins Bax, cleaved-caspase3, Bcl-2. Flow cytometry was applied to examine neuronal cell apoptosis. RNA pull-down and RIP assay was used to verify the binding of MIAT and REDD1. The level of REDD1 ubiquitination was detected by ubiquitination and Co-immunoprecipitation (Co-IP) assay.

Results: The expressions of MIAT and REDD1 were increased in IS rats and oxygen-glucose deprivation/reoxygenation (OGD/R)-induced PC12 cell injury. After interference with si-MIAT, the results of flow cytometry showed that the rate of apoptosis was reduced. Western blotting results showed that the expression of LC3II/LC3I, Bax, and cleaved-caspase3 was decreased, while the expression of p-mTOR, p62, and Bcl-2 was increased. RNA pull-down and RIP assay found the binding relationship between MIAT and REDD1, and interference with si-MIAT down-regulated the expression of REDD1. The level of REDD1 ubiquitination was increased and the expression of REDD1 was decreased after interference with si-MIAT in PC12 cells. Co-IP results showed that interference with si-MIAT enhanced the binding ability of CUL4A-DDB1 and REDD1.

Conclusion: Altogether, MIAT promotes autophagy and apoptosis of neural cells and aggravates IS by up-regulating the expression of REDD1.
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http://dx.doi.org/10.1016/j.brainres.2021.147436DOI Listing
July 2021

The complete chloroplast genome sequence of Hu et S.Y. Liang ().

Mitochondrial DNA B Resour 2020 Sep 17;5(3):3363-3365. Epub 2020 Sep 17.

Co-Innovation Center for Sustainable Forestry in Southern China, College of Biology and the Environment, Key Laboratory of State Forestry and Grassland Administration on Subtropical Forest Biodiversity Conservation, Nanjing Forestry University, Nanjing, PR China.

Hu et S.Y. Liang, is one of the few evergreen species of with fragrant flowers. Here, we characterized the complete chloroplast (cp) genome of using next-generation sequencing. The circular complete cp genome of is 158,502 bp in length, containing a large single-copy (LSC) region of 87,817 bp, and a small single-copy (SSC) region of 18,001 bp. It comprises 132 genes, including 8 genes, 37 genes, and 87 protein-coding genes. The GC content of cp genome is 36.93%. The phylogenetic analysis suggests that is a sister species to in .
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http://dx.doi.org/10.1080/23802359.2020.1821822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782962PMC
September 2020

The complete chloroplast genome sequence of (Lindl.) Schott (Fagaceae).

Mitochondrial DNA B Resour 2020 Jul 15;5(3):2848-2849. Epub 2020 Jul 15.

Co-Innovation Center for Sustainable Forestry in Southern China, College of Biology and the Environment, Key Laboratory of State Forestry and Grassland Administration on Subtropical Forest Biodiversity Conservation, Nanjing Forestry University, Nanjing, PR China.

(Lindl.) Schott is one of the National Class II protected plants, and an important species in subtropical evergreen forests in China. The object of this work was to thoroughly explore the complete chloroplast (cp) genome of . using next-generation sequencing. The circular complete cp genome of . is 160,519 bp in length, containing a large single-copy (LSC) region of 90,243 bp, and a small single-copy (SSC) region of 18,976 bp. It comprises 131 genes, including 8 rRNA genes, 37 tRNAs genes, and 85 protein-coding genes. The GC content of cp genome is 36.81%. The phylogenetic analysis suggests that . is a sister species to . in Fagaceae.
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http://dx.doi.org/10.1080/23802359.2020.1790324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781992PMC
July 2020

Circular RNA circ_DROSHA alleviates the neural damage in a cell model of temporal lobe epilepsy through regulating miR-106b-5p/MEF2C axis.

Cell Signal 2021 Apr 25;80:109901. Epub 2020 Dec 25.

Department of Neurology, Huaihe Hospital of Henan University, Kaifeng 475000, Henan, China. Electronic address:

Temporal lobe epilepsy (TLE) is the most prevalent form of acquired epilepsy. Circular RNAs (circRNAs) have recently been highlighted as important regulators in TLE. Nevertheless, the role and mechanism of circRNA Drosha ribonuclease III (circ_DROSHA) in TLE pathogenesis are still unknown. Magnesium-free extracellular solution was used to establish the TLE cell model. The levels of circ_DROSHA, myocyte-specific enhancer factor 2C (MEF2C) and miR-106b-5p were determined by qRT-PCR and western blot. Cell proliferation was detected by the Cell Counting-8 Kit (CCK-8) assay, and cell apoptosis was measured by flow cytometry. Targeted relationships among circ_DROSHA, miR-106b-5p and MEF2C were confirmed by a dual-luciferase reporter or RNA immunoprecipitation (RIP) assay. Our data showed that circ_DROSHA was down-regulated in the serum samples of TLE patients and the TLE cell model. Circ_DROSHA up-regulation alleviated the cytotoxicity of the TLE cell model by enhancing cell proliferation and repressing cell apoptosis. Circ_DROSHA directly bound to miR-106b-5p. Moreover, miR-106b-5p represented a downstream effector of circ_DROSHA function. MEF2C was a direct target of miR-106b-5p, and miR-106b-5p knockdown relieved magnesium-free treatment-induced cell injury by up-regulating MEF2C. Furthermore, circ_DROSHA regulated MEF2C expression via sponging miR-106b-5p. Our study suggested that the enforced expression of circ_DROSHA alleviated the cell damage of the TLE cell model at least in part through the regulation of the miR-106b-5p/MEF2C axis.
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http://dx.doi.org/10.1016/j.cellsig.2020.109901DOI Listing
April 2021

The complete chloroplast genome sequence of Perkins (Styracaceae).

Mitochondrial DNA B Resour 2020 Feb 3;5(1):1029-1030. Epub 2020 Feb 3.

School of Horticulture & Landscape Architecture, Jinling Institute of Technology, Nanjing, China.

The object of this work was to measure the complete chloroplast genome of Perkins for the sake of offering valuable genomic information to promote its conservation. The circular genome of was measured as 157,913 bp in size and contained two inverted repeat (IRa and IRb) regions of 26,040 bp, which were separated by a large single-copy (LSC) region of 87,604 bp and a small single copy (SSC) region of 18,229 bp. A total of 134 genes are encoded, including 89 protein-coding genes, 37 tRNA genes, and 8 rRNA genes. The overall GC content of genome is 36.97%. A phylogenetic tree reconstructed using 36 chloroplast genomes reveals that is most closely related with and
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http://dx.doi.org/10.1080/23802359.2020.1722039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748768PMC
February 2020

The complete chloroplast genome of Perkins (Styracaceae).

Mitochondrial DNA B Resour 2020 Jan 31;5(1):961-962. Epub 2020 Jan 31.

School of Horticulture and Landscape Architecture, Jinling Institute of Technology, Nanjing, China.

In this work, next-generation sequencing was applied to measure the complete chloroplast genome of for the sake of offering valuable genomic information to promote its conservation. The complete chloroplast genome sequence of was measured as 157,501 bp in size. It contains the typical structure and gene content of angiosperm plastome, which includes a large single-copy (LSC), a small single-copy (SSC), and 2 inverted repeat (IR) regions of 87,130 bp, 18,277 bp, and 26,047 bp, respectively. The chloroplast genome has a total of 130 genes including 85 protein-coding genes, 37 tRNA genes, and 8 rRNA genes. Overall, GC contents of the genome were 36.96%. Phylogenetic analysis based on the 29 chloroplast genome measurement demonstrated that is most closely related to Griff.
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http://dx.doi.org/10.1080/23802359.2020.1721375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748644PMC
January 2020

The complete chloroplast genome of Hemsl. (Styracaceae).

Mitochondrial DNA B Resour 2020 Jan 24;5(1):828-829. Epub 2020 Jan 24.

School of Horticulture and Landscape Architecture, Jinling Institute of Technology, Nanjing, China.

Hemsl. is valued for its beauty and fragrance. Here, we characterized the complete chloroplast (cp) genome of . using next-generation sequencing. The circular complete cp genome of was 157,981 bp in length, containing a large single-copy (LSC) region of 87,571 bp, and a small single-copy (SSC) region of 18,316 bp. It comprises 133 genes, including eight rRNA genes, 37 tRNA genes, and 88 protein-coding genes. The GC content of cp genome is 36.95%. A phylogenetic tree reconstructed by 30 chloroplast genomes reveals that is mostly related to Perk.
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http://dx.doi.org/10.1080/23802359.2020.1715890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748495PMC
January 2020

The complete chloroplast genome sequence of (Styracaceae).

Mitochondrial DNA B Resour 2020 Jan 24;5(1):804-805. Epub 2020 Jan 24.

School of Horticulture and Landscape Architecture, Jinling Institute of Technology, Nanjing, China.

is valued for its beauty and fragrance. Here, we characterized the complete chloroplast (cp) genome of using next generation sequencing. The circular complete cp genome of is 158,027 bp in length, containing a large single-copy (LSC) region of 87,641 bp, and a small single-copy (SSC) region of 18,290 bp. It comprises 133 genes, including 8 rRNA genes, 37 tRNAs genes, and 88 protein-coding genes. The GC content of cp genome is 36.95%. The phylogenetic analysis suggests that is a sister species to in Styracaceae.
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http://dx.doi.org/10.1080/23802359.2020.1715861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748421PMC
January 2020

The complete chloroplast genome sequence of Perk. (Styracaceae).

Mitochondrial DNA B Resour 2020 Jan 22;5(1):770-771. Epub 2020 Jan 22.

Co-Innovation Center for Sustainable Forestry in Southern China, College of Biology and the Environment, Key Laboratory of State Forestry and Grassland Administration on Subtropical Forest Biodiversity Conservation, Nanjing Forestry University, Nanjing, China.

Perk., is a nice tree, valued for its beauty and fragrance. Here, we characterized the complete chloroplast (cp) genome of using next-generation sequencing. The circular complete cp genome of is 157,951 bp in length, containing a large single-copy (LSC) region of 87,566 bp and a small single-copy (SSC) region of 18,289 bp. It comprises of 133 genes, including 8 rRNA genes, 37 tRNAs genes, and 88 protein-coding genes. The GC content of cp genome is 36.95%. The phylogenetic analysis suggests that is a sister species to Griffith in Styracaceae.
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http://dx.doi.org/10.1080/23802359.2020.1715869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748754PMC
January 2020

The complete chloroplast genome sequence of (Styracaceae).

Mitochondrial DNA B Resour 2020 Jan 14;5(1):564-565. Epub 2020 Jan 14.

College of Biology and Environment, Nanjing Forestry University, Nanjing, China.

Siebold & Zucc. is a distinct member of the family Styracaceae with fragrant and beautiful flowers. In this study, we determined the complete chloroplast (cp) genome sequence of in an effort to provide genomic resources useful for promoting its conservation. The circular genome of was 157,910 bp in size and contained two inverted repeat (IRa and IRb) regions of 26,051 bp, which were separated by a large single copy (LSC) region of 87,528 bp, and a small single copy (SSC) region of 18,280 bp. A total of 133 genes are encoded, including 88 protein-coding genes, 37 tRNA genes, and eight rRNA genes. The overall GC content of genome is 36.97%. The phylogenetic analysis suggests that is a sister species to and in Styracaceae.
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http://dx.doi.org/10.1080/23802359.2019.1710290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748812PMC
January 2020

The complete chloroplast genome of Perk. (Styracaceae).

Mitochondrial DNA B Resour 2019 Dec 12;5(1):98-99. Epub 2019 Dec 12.

College of Biology and Environment, Nanjing Forestry University, Nanjing, Jiangsu, China.

Perk., a native plant belonging to Styracaceae mainly distributed in the region south of the Yantze River, China, is both a medicinal and landscape plant. Here we studied the complete chloroplast (cp) genome sequence of . by using next-generation sequencing. The whole complete cp genome of . totals 159,424 bp in length, containing a large single-copy (LSC) region of 85,845 bp, and a small single-copy (SSC) region of 18,027 bp 133 genes, including 8 rRNA genes, 37 tRNAs genes, and 88 protein-coding genes constituted the genome. The GC content of is 36.92%. The phylogenetic analysis reveals that . is a sister species to and in .
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http://dx.doi.org/10.1080/23802359.2019.1698351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721051PMC
December 2019

The complete chloroplast genome sequence of (Styracaceae).

Mitochondrial DNA B Resour 2019 Nov 13;4(2):4053-4054. Epub 2019 Nov 13.

College of Biology and Environment, Nanjing Forestry University, Nanjing, China.

Hu (Styracaceae) is a rare endemic tree of Styracaceae in China. In this work, we set forth the complete chloroplast (cp) genome sequence of using next-generation sequencing. The entire cp genome was determined to be 157,196 bp in length. It contained large single-copy (LSC) and small single-copy (SSC) regions of 90,210 bp and 18,4561 bp, respectively, which were separated by a pair of 24,265 bp inverted repeat (IR) regions. The genome contained 128 genes, including 83 protein-coding genes, 37 tRNA genes, and eight rRNA genes. The overall GC content of the genome is 37.19%. Phylogenetic analysis confirmed the traditional family-level Taxonomy of , indicating that is closely related to a sister species to in Styracaceae.
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http://dx.doi.org/10.1080/23802359.2019.1688707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707757PMC
November 2019

The complete chloroplast genome sequence of (Styracaceae).

Mitochondrial DNA B Resour 2019 Nov 14;4(2):4051-4052. Epub 2019 Nov 14.

College of Biology and Environment, Nanjing Forestry University, Nanjing, China.

Champ. ex Benth., also known as the extraordinary aromatic plant of Styracaceae, has been seriously threatened due to human activities. In this study, the complete chloroplast (cp) genome sequence of was determined by applying next-generation sequencing. The entire cp genome was determined to be 157,921 bp in length. It contained large single-copy (LSC) and small single-copy (SSC) regions of 87,524 bp and 18,301 bp, respectively, which were separated by a pair of 26,048 bp inverted repeat (IR) regions. The genome contained 130 genes, including 85 protein-coding genes, 37 tRNA genes, and 8 rRNA genes. The overall GC content of genome is 36.96% and the corresponding values in LSC, SSC, and IR regions are 34.80, 30.27, and 42.92%, respectively. A phylogenetic tree reconstructed by 31 chloroplast genomes reveals that is most related to Griffith.
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http://dx.doi.org/10.1080/23802359.2019.1688705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707729PMC
November 2019

Yeast biomass-induced CoP/biochar composite for sulfonamide antibiotics degradation through peroxymonosulfate activation.

Environ Pollut 2021 Jan 31;268(Pt B):115930. Epub 2020 Oct 31.

School of Chemical Engineering, Sichuan University, Chengdu, 610065, China. Electronic address:

Advanced oxidation processes (AOPs) based on peroxymonosulfate (PMS) activation have attracted increasing attention in recent years for organic pollutants removal. Herein, we put forward a facile method to form cobalt phosphide/carbon composite for PMS activation. Combining impregnation approach with pyrolysis treatment enabled the formation of CoP/biochar composites using baker's yeast and Co as precursors. The as-synthesized products exhibited excellent catalytic activity for sulfamethoxazole (SMX) degradation over the pH range 3.0-9.0 b y activating PMS. For example, 100% of SMX (20 mg L) removal was achieved in 20 min with catalyst dosage of 0.4 g L and PMS loading of 0.4 g L. Near zero Co leaching was observed during catalytic reaction, which remarkably lowered the toxic risk of transition metal ion in water. Meanwhile, the reusability of catalyst could be attained by thermal treatment. SMX degradation intermediates were identified by liquid chromatography-mass spectrometry (LC-MS), which facilitated the proposal of possible SMX degradation pathways. Ecological Structure Activity Relationships (ECOSAR) analysis indicated that SMX degradation intermediates may not pose ecological toxicity to the environment. Further investigation verified that CoP/biochar composites could set off PMS activation not only for the degradation of SMX but also for other sulfonamides. In this study, we not only developed a facile method of utilizing environmental-benign biomass for transition metal phosphide/carbon composite formation, but also achieved highly efficient antibiotic elimination by PMS-based AOP.
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http://dx.doi.org/10.1016/j.envpol.2020.115930DOI Listing
January 2021

Temperature signal recorded in δH and δC values of wood lignin methoxyl groups from a permafrost forest in northeastern China.

Sci Total Environ 2020 Jul 8;727:138558. Epub 2020 Apr 8.

Institute of Earth Sciences, Heidelberg University, Im Neuenheimer Feld 234-236, 69120 Heidelberg, Germany; Heidelberg Center for the Environment HCE, Heidelberg University, D-69120 Heidelberg, Germany.

Stable isotopes in wood lignin methoxyl groups (δH and δC values) have been suggested as valuable complementary paleoclimate proxies. In permafrost forests, tree growth is influenced by multiple factors, however temperature appears to have the strongest impact on tree growth and, therefore, on carbon cycling. To test whether δH and δC values of trees from permafrost regions might record climate parameters, two dominant tree species (Larix gmelinii, larch, and Pinus sylvestris var. mongolica, pine) collected from a permafrost forest in China's Greater Hinggan Mountains, were investigated. The two tree species larch and pine covered time spans of 1940 to 2013 and 1870 to 2013, respectively. Results showed significant correlations of pine and larch δH values and larch δC values with temperatures and in particular with the mean temperature of the growing season from April to August. However, only weak correlations of δH and δC values with moisture conditions, such as precipitation amount and relative humidity were observed. In addition, species specificity in the climate response was most obvious for δC values. Compared to a temperature reconstruction based on tree ring width, pine δH-based reconstruction showed strongest spatial correlations with regional temperature. Therefore, δH values might be a promising proxy to reconstruct growing-season temperatures in permafrost regions.
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http://dx.doi.org/10.1016/j.scitotenv.2020.138558DOI Listing
July 2020

Direct conversion of wet sewage sludge to carbon catalyst for sulfamethoxazole degradation through peroxymonosulfate activation.

Sci Total Environ 2020 Aug 22;728:138853. Epub 2020 Apr 22.

Department of Pharmaceutical & Biological Engineering, School of Chemical Engineering, Sichuan University, Chengdu 610065, China. Electronic address:

The high moisture content of wet sewage sludge generated from wastewater treatment process not only brings high cost of sewage disposal, but also limits its utilization as resource. In this study, an efficient strategy of directly utilizing wet sludge to develop advanced carbocatalyst via a hydrothermal coupled pyrolysis process was proposed. The possible application of as-synthesized carbocatalyst was evaluated by activating peroxymonosulfate (PMS) to degrade a model pollutant of sulfamethoxazole (SMX). Experimental results showed that about 100% of SMX and 59% of total organic carbon (TOC) could be removed within 15 min. Moisture content in wet sludge also affected the performances of as-obtained carbocatalysts. Further studies verified that singlet oxygen (O) dominated SMX degradation, which was generated in the process of PMS activation by CO groups on the surface of carbocatalyst. In the preliminary ecological test, a lower ecotoxicity of SMX degradation solution compared with the original solution was observed. This study demonstrated the feasibility of directly utilizing wet sludge for advanced carbocatalyst fabrication, which provided another solution for wet sludge treatment and utilization.
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http://dx.doi.org/10.1016/j.scitotenv.2020.138853DOI Listing
August 2020

Modified Blalock-Taussig Shunt: A Single-Center Experience and Follow-Up.

Heart Surg Forum 2020 02 25;23(1):E053-E057. Epub 2020 Feb 25.

Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Sichuan, P.R. China.

Background: The modified Blalock-Taussig shunt (MBTS) is used to palliate patients with restrictive pulmonary blood flow in complex cardiac anomalies. We describe the immediate and follow-up results of patients with MBTS in our center.

Methods: Patients who received MBTS (excluding those with hypoplastic left heart syndrome) from May 2008 to December 2018 were retrospectively identified. Hospital records were evaluated to determine patient demographics, diagnoses, and perioperative data. Patients were followed up by echocardiograph to evaluate the patency of the graft until stage II procedure or death.

Results: MBTS was performed in 25 patients by 2 surgeons; 16% were neonates, and 60% had pulmonary atresia and 24% tetralogy of Fallot. The patients' median age was 2.6 months (range 0.2 to 372), and median weight was 5.3 kg (range 1.9 to 45). Preoperative oxygen saturation (SaO2) was 68.7% ± 7.8%. Forty-eight percent of patients received a 3.5-mm graft, and 20% received a concomitant pulmonary arterioplasty with cardiopulmonary bypass. Postoperative SaO2 was 83.2% ± 3.6%, significantly different from preoperative SaO2 (P < .05). Follow-up duration was 1.2 years (range 0.3 to 7.8), with no graft blockage. Three patients died in hospital from cardiorespiratory decompensation after MBTS with concomitant pulmonary arterioplasty. The median age of patients receiving a stage II procedure was 1 year (range 0.4 to 17.4). Actuarial 1-year survival was 79.7% (95% confidence interval 53.1% to 92.2%).

Conclusion: MBTS continues to be valuable for palliation of complicated cyanotic congenital heart disease, yet mortality was considerable with concomitant pulmonary arterioplasty. With effective coagulation, the patency rate of grafts was high.
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http://dx.doi.org/10.1532/hsf.2715DOI Listing
February 2020

Population Structure and Aggressiveness of From Rapeseed () in Chongqing City.

Plant Dis 2020 Apr 17;104(4):1201-1206. Epub 2020 Feb 17.

College of Plant Protection, Southwest University, Chongqing City, 400715, People's Republic of China.

is one of the most devastating fungal plant pathogens of oilseed and is distributed worldwide. In particular, stem rot has always been a serious threat to rapeseed production in Chongqing City, China. In this study, simple sequence repeat (SSR) markers and mycelial compatibility groups (MCGs) were used to characterize the population structure of 90 geographic isolates of collected from rapeseed in nine counties of Chongqing. A total of 52 microsatellite haplotypes were identified, and a few haplotypes were found with high frequency. Gene diversity ranged from 0.1570 to 0.4700 in nine populations. A constructed unweighted pair group with arithmetic mean dendrogram based on Nei genetic distance and a STRUCTURE analysis revealed that the genetic composition of the isolates collected in the five counties located in western Chongqing are different from those collected in the two eastern counties, suggesting that breed lines should be cultivated in both the western and eastern regions to effectively evaluate resistance levels. A total of 47 MCGs were identified, and 72% of the MCGs was represented by single isolates. Seven of 13 MCGs that included at least two isolates contained isolates from only one county. SSR haplotypes were not correlated with MCGs. A subset of 34 isolates were inoculated on rapeseed stems, and the aggressiveness showed variation. This research revealed the population genetic structure and aggressiveness of this pathogen in Chongqing, and the results will help to develop disease management and resistance screening strategies.
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http://dx.doi.org/10.1094/PDIS-07-19-1401-REDOI Listing
April 2020

Molten salt induced nitrogen-doped biochar nanosheets as highly efficient peroxymonosulfate catalyst for organic pollutant degradation.

Environ Pollut 2020 May 23;260:114053. Epub 2020 Jan 23.

Department of Pharmaceutical & Biological Engineering, School of Chemical Engineering, Sichuan University, Chengdu, 610065, PR China. Electronic address:

Advanced oxidation processes based on carbon catalysis is a promising strategy possessing great potential for environmental pollution degradation. Herein, nitrogen-doped biochar nanosheets (NCS-x) were synthesized using a nitrogen-rich biomass (Candida utilis) as sole precursor. The involvement of environmental-friendly molten salt (NaCl and KCl) in pyrolysis process not only facilitated the exfoliation of biochar, but also favored the retention of N element in biochar. When applying as catalyst for peroxymonosulfate activation, the as-obtained NCS-6 exhibited outstanding performance in catalytic degradation of bisphenol A (BPA). A 100% removal efficiency was observed in 6 min with fast reaction kinetic (k = 1.36 min). Based on quenching test and in-situ electron paramagnetic resonance analysis, both radical pathway and non-radical pathway were suggested to be involved in BPA degradation, while singlet oxygen was identified as the dominant reactive oxygen species. Furthermore, the ecotoxicity evaluation using Chlorella vulgaris as ecological indicator indicated that BPA solution after degradation was less toxic than the original solution. It is expected that this green and facile strategy holds great promise for value-added conversion of nitrogen-rich biomass to highly efficient biochar nanosheets for environment remediation.
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http://dx.doi.org/10.1016/j.envpol.2020.114053DOI Listing
May 2020

Surgical removal of part of an occluder to treat iatrogenic coarctation of the aorta: a case report.

BMC Surg 2020 Jan 17;20(1):17. Epub 2020 Jan 17.

Department of Cardiovascular Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, Sichuan, China.

Background: Iatrogenic aortic stenosis is a serious complication and potentially fatal due to erosion of the aortic wall. Timely management is necessary to prevent complications.

Case Presentation: A 2-year-old boy underwent surgery to remove part of an Amplatzer occluder after patent ductus arteriosus (PDA) device embolization in the thoracic aorta. He exhibited moderate to severe obstruction with erosion of the intimal layer of the aorta caused by the device, part of which was retrieved surgically with restructuring of the thoracic aorta segment and occluder remnant. The patient's postoperative course was uneventful.

Conclusions: When possible, retrieving only part of an embolized device can be advocated because it reduces the risk of aortic and pulmonary artery damage.
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http://dx.doi.org/10.1186/s12893-020-0682-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969450PMC
January 2020

Enhanced Cr(VI) removal by waste biomass derived nitrogen/oxygen co-doped microporous biocarbon.

Environ Sci Pollut Res Int 2020 Feb 17;27(5):5433-5445. Epub 2019 Dec 17.

Department of Pharmaceutical & Biological Engineering, School of Chemical Engineering, Sichuan University, No. 24 South Section 1, Yihuan Road, Chengdu, 610065, People's Republic of China.

Herein, kitchen waste hydrolysis residue (KWHR) was utilized as the precursor to fabricate nitrogen/oxygen co-doped microporous biocarbons (NOMBs) with ultrahigh specific surface area via KOH activation. Activation temperature was found to be crucial for heteroatom doping and pore structure construction. Attractively, the obtained NOMB with high surface area (2417 m/g) and microporosity (~ 90%) displayed an outstanding capacity of Cr(VI) removal (526.1 mg/g at pH 2). The kinetics and isotherm studies showed that the adsorption of Cr(VI) onto NOMB was well described by the pseudo-second-order kinetics and Langmuir isotherm. Moreover, it was found that Cr(VI) was partly reduced to Cr(III) during the removal process as the nitrogen/oxygen functionalities and unsaturated carbon bond played crucial roles of electron-donors, which revealed the fact that the removal of Cr(VI) by NOMB was attributed to the coupling of adsorption and reduction reaction. Overall, this study has demonstrated the possibility of preparing microporous biocarbons using KWHR as a renewable material and the resultant NOMB is of great potential to detoxify Cr(VI).
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http://dx.doi.org/10.1007/s11356-019-07330-0DOI Listing
February 2020

Hydrothermal route-enabled synthesis of sludge-derived carbon with oxygen functional groups for bisphenol A degradation through activation of peroxymonosulfate.

J Hazard Mater 2020 04 30;388:121801. Epub 2019 Nov 30.

Department of Pharmaceutical & Biological Engineering, School of Chemical Engineering, Sichuan University, Chengdu 610065, China. Electronic address:

A considerable amount of sewage sludge (SS) is generated from wastewater treatment process, which is hazardous to the environment and in urge to be disposed. In this study, for the first time, we prepared carbocatalyst with abundant surface oxygen functional groups using the hazardous waste of SS as precursor via a facile hydrothermal coupled pyrolysis process. The hydrothermal treatment was found to be crucial for enhancing the oxygen content of sludge carbon (SC), most of which existed as ketonic groups. Catalytic performances of the developed SCs were examined by activating peroxymonosulfate (PMS) to degrade bisphenol A (BPA). Sample with more ketonic group performed better for BPA degradation. Under optimal reaction conditions, 100 % of BPA and 69.53 % of TOC could be removed in 20 min. Singlet oxygen (O) was suggested to be the main reactive oxygen species for degrading BPA and a BPA degradation pathway was proposed. The BPA solution showed decreased bio-toxicity after the oxidation process according to the acute ecotoxicity test. This study demonstrated the importance of surface functional groups on carbocatalyst for advanced oxidation process, which could be induced by a facile hydrothermal treatment. The feasibility of utilizing hazardous SS for advanced carbocatalyst fabrication was also revealed.
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http://dx.doi.org/10.1016/j.jhazmat.2019.121801DOI Listing
April 2020

Treatment with 3-aminobenzamide during ex vivo lung perfusion of damaged rat lungs reduces graft injury and dysfunction after transplantation.

Am J Transplant 2020 04 4;20(4):967-976. Epub 2019 Dec 4.

Service of Adult Intensive Care Medicine, Faculty of Biology and Medicine, University Hospital of Lausanne, Lausanne, Switzerland.

Ex vivo lung perfusion (EVLP) with pharmacological reconditioning may increase donor lung utilization for transplantation (LTx). 3-Aminobenzamide (3-AB), an inhibitor of poly(ADP-ribose) polymerase (PARP), reduces ex vivo lung injury in rat lungs damaged by warm ischemia (WI). Here we determined the effects of 3-AB reconditioning on graft outcome after LTx. Three groups of donor lungs were studied: Control (Ctrl): 1 hour WI + 3 hours cold ischemia (CI) + LTx; EVLP: 1 hour WI + 3 hours EVLP + LTx; EVLP + 3-AB: 1 hour WI + 3 hours EVLP + 3-AB (1 mg mL ) + LTx. Two hours after LTx, we determined lung graft compliance, edema, histology, neutrophil counts in bronchoalveolar lavage (BAL), mRNA levels of adhesion molecules within the graft, as well as concentrations of interleukin-6 and 10 (IL-6, IL-10) in BAL and plasma. 3-AB reconditioning during EVLP improved compliance and reduced lung edema, neutrophil infiltration, and the expression of adhesion molecules within the transplanted lungs. 3-AB also attenuated the IL-6/IL-10 ratio in BAL and plasma, supporting an improved balance between pro- and anti-inflammatory mediators. Thus, 3-AB reconditioning during EVLP of rat lung grafts damaged by WI markedly reduces inflammation, edema, and physiological deterioration after LTx, supporting the use of PARP inhibitors for the rehabilitation of damaged lungs during EVLP.
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http://dx.doi.org/10.1111/ajt.15695DOI Listing
April 2020

The complete chloroplast genome sequence of (Styracaceae).

Mitochondrial DNA B Resour 2019 Oct 21;4(2):3677-3678. Epub 2019 Oct 21.

College of Biology and Environment, Nanjing Forestry University, Nanjing, China.

Handel-Mazzetti is a rare tree, distinct member of the family Styracaceae. In this study, we determined the complete chloroplast (cp) genome sequence of in an effort to provide genomic resources useful for promoting its conservation. The entire cp genome was determined to be 157,165 bp in length. It contains the typical structure and gene content of angiosperm plastome, The plastome contains a large single-copy (LSC) and a small single-copy (SSC) regions of 90,193 and 18,486 bp, respectively, which were separated by a pair of 24,243 bp inverted repeat (IR) regions. The genome contained 130 genes, including 85 protein-coding genes, 37 tRNA genes, and 8 rRNA genes. The GC content of genome is 37.21%. The complete plastome sequence of will provide a useful resource for the conservation genetics of this species as well as for the phylogenetic studies for Styracaceae. Phylogenetic analysis revealed that is closely related to H.S.Lo & D.Fang, but forms an independent evolutionary branch.
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http://dx.doi.org/10.1080/23802359.2019.1677521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707565PMC
October 2019
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