Publications by authors named "Y J Patil"

144 Publications

Isolation and development of a microbial consortium for the treatment of automobile service station wastewater.

J Appl Microbiol 2021 Aug 28. Epub 2021 Aug 28.

Symbiosis Centre for Research and Innovation, Symbiosis International (Deemed University), Pune, India.

Aim: This work aims to investigate the nature of waste being generated by automobile service stations (ASS) and to devise a microbial-based formulation for the treatment of ASS wastewater.

Methods And Results: Analysis of soil and water samples from the vicinity of different ASS in and around the Pune city region (India) revealed the presence of significant amounts of many heavy metals including zinc (Zn) 13.8-175.44 mg kg , nickel (Ni) 0.6-5.5 mg kg and copper (Cu) 8.07-179.2 mg kg as well as oil and grease (O&G). A consortium, consisting of selected members from the ASS soil bacterial isolates, was formulated. The selection of consortium members was based on their ability to degrade hydrocarbons, tolerate heavy metals, and produce biosurfactant and lipase. The developed microbial consortium was capable of reducing the concentration of Ni, manganese (Mn) and chromium (Cr) by 69.25%, 14.63% and 84.93%, respectively, and O&G by 71.8% in the aqueous medium under laboratory conditions.

Conclusions: Wastewater and soil analysis confirmed the presence of a high amount of O&G and metals in and around ASS. The developed microbial consortium holds potential for the treatment of wastewater rich in O&G and heavy metals.

Significance And Impact Of The Study: There is a dearth of scientific studies in India on the wastewater and polluted soils associated with ASS. This work reveals and confirms the hazardous nature of ASS and the need for the development and feasibility of microbial-based technology for the sustainable bioremediation of such sites.
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http://dx.doi.org/10.1111/jam.15257DOI Listing
August 2021

Photoinduced Charge Separation Prompted Intervalence Charge Transfer in a Bis(thienyl)diketopyrrolopyrrole Bridged Donor-TCBD Push-Pull System.

Angew Chem Int Ed Engl 2021 Sep 6;60(37):20518-20527. Epub 2021 Aug 6.

Department of Chemistry, University of North Texas, 1155 Union Circle, #305070, Denton, TX, 76203-5017, USA.

Intervalence charge transfer (IVCT), a phenomenon observed in molecular systems comprised of two redox centers differing in oxidation states by one unit, is reported in a novel, newly synthesized, multi-modular donor-acceptor system comprised of central bis(thienyl)diketopyrrolopyrrole (TDPP) hosting two phenothiazine-tetracyanobutadiene (PTZ-TCBD) entities on the opposite sides. One-electron reduction of TCBD promoted electron exchange between the two TCBD resulting in IVCT transition in the near-infrared region. The stabilization energy, -ΔG and comproportionation equilibrium constant, K calculated from peak potentials of the split reduction waves were found to be 1.06×10  J mol , and 72.3 M , respectively. Further, the IVCT transition was also witnessed during the process of thermodynamically feasible electron transfer upon excitation of the TDPP entity in the system, and served as a diagnostic marker to characterize the electron transfer product. Subsequent transient absorption spectral studies and data analysis by Global and Target analyses revealed occurrence of ultrafast charge separation (k ≈10  s ) owing to the close proximity and good communication between the entities of the multi-modular donor-acceptor system. The role of central TDPP in promoting IVCT is borne out from the present investigation.
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http://dx.doi.org/10.1002/anie.202108293DOI Listing
September 2021

A Report on the Use of Telehealth in Otolaryngology: In the Pre COVID-19 Era.

Telemed J E Health 2021 May 21. Epub 2021 May 21.

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1089/tmj.2021.0049DOI Listing
May 2021

Modified Head and Neck Swallow Scale: Using EORTC-QLQ-H&N35 to Predict Overall Survival.

Laryngoscope 2021 Apr 24. Epub 2021 Apr 24.

Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, U.S.A.

Objectives/hypothesis: Dysphagia is a treatment-related complication of head and neck cancer (HNCA). We demonstrate the predictive value of a modified head and neck swallow scale (m-HNSW) adapted from the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Head and Neck 35 (EORTC-QLQ-H&N35).

Study Design: Retrospective Cohort Study.

Methods: Retrospective, single-center cohort study utilizing a prospectively collected database of HNCA patients in a high-volume tertiary referral center. 736 HNCA patients more than 2 years from completion of treatment were identified. EORTC-QLQ-H&N35 data collected from at least one of three defined episodes of care were used. The m-HNSW uses three questions to form a 9-point dysphagia scale. A Cox proportional hazards model was used to determine the effect of the m-HNSW while controlling for demographics, tumor staging, site, and treatment.

Results: Using data from 3, 6, 12 months from treatment, we analyzed a subset that included 328 patients. Three months after the completion of therapy, the m-HNSW score had a significant association with 1 (HR = 1.24, P = .0005) and 5 year survival (HR = 1.19, P = .0002) after accounting for body mass index. Six (HR = 1.14, P = .014) and 12 month (hazard ratio (HR) = 1.33, P < .0001) scores post completion of therapy predict 5-year survival. An increase of the m-HNSW score by 1 point was associated with an increase in death by 24%, and 19% at 1 and 5 years following therapy.

Conclusions: The m-HNSW is a simple assessment of dysphagia using previously validated EORTC-QLC-H&N35 data that when taken at 3, 6, and 12 months after completion of therapy is predictive of overall survival.

Level Of Evidence: 4 Laryngoscope, 2021.
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http://dx.doi.org/10.1002/lary.29559DOI Listing
April 2021

Genetic Mapping of a new allele, in .

MicroPubl Biol 2021 Apr 8;2021. Epub 2021 Apr 8.

School of Science, Technology, and Mathematics, Ohio Northern University, Ada, OH USA.

Genetic screens provide a mechanism to identify genes involved with different cellular and organismal processes. Using a Flp/FRT screen in the eye we identified mutations that result in alterations and de-regulation of cell growth and division. From this screen a group of undergraduate researchers part of the Fly-CURE consortium mapped and characterized a new allele of the gene ,
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http://dx.doi.org/10.17912/micropub.biology.000383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033417PMC
April 2021
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